LOCUS       NC_021039.1            22960 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021039.1 Ruminococcus champanellensis 18P13 = JCM 17042, complete
            sequence.
ACCESSION   NC_021039
VERSION     NC_021039.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:45:53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 662781
            Orig. end    :: 685741
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22960
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[672781:675741]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12960
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..22960
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22960
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             203..943
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_606"
                     /sec_met_domain="CbiA (E-value: 3.9e-18, bitscore: 62.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVIAVTSGKGGTGKSSICSGLGYTLAKQGSRTLIIELDFGLRC
                     IDIIFGMQGKIKYDLGDVLHNRVKPLDAVTQVPMASNLNILCAPKDPFASATVEQIVDI
                     CKQIRKYFDYIIIDTGAGINSHVFDIVEQANTILVVTTPDPICVRDAQMMSDEFYNRGN
                     KRQRLIINKVNKRAIGSELVKSLDEIIDTIGVQLIGVIPEDYELVIATGKGQPIPSTAP
                     SLAAFDAIAKRLKGENAPLTVKIK"
     CDS             1013..1417
                     /locus_tag="ctg1_607"
                     /transl_table=11
                     /translation="MNIALIAHDSKKELMIQFCIAYCGILSRHNLCATGTTGKQVSEAT
                     GLHIQRYLSGSQGGDQQICARISCNEIDVLLFFRDPINPKSNEPNDMNLLRLCDVHNVP
                     VATNIATAEALILALERGDLDWREIGNPSL"
     CDS             1541..2848
                     /locus_tag="ctg1_608"
                     /transl_table=11
                     /translation="MALNLKRPNGTEDITPANIHKWYTVEQVARSVAQSYGFREIRIPT
                     FENTELFQRSVGETTDVVQKEMYTVMAKETKFTLRPEGTAGTIRAMLQNGLLNEALPQK
                     VFYLLSCFRHERPQAGRLREFHQFGLEMAGSAEPVADAEVISLAKAVLDTLGLKGIQLY
                     INSIGCPTCRAEYHKALRAYFEARKDQLCDTCLSRLEKNPMRILDCKSPICGELGKDAP
                     VILDYLCEDCKTHFEKLQGYLKAMDIDFSINPKIVRGLDYYTKTVFEFVTTDIGAQGTV
                     CGGGRYDGLIEELGGQHQPALGFAMGIERLLLTMESQGCDFLEPNHCDLYIATMDPEGV
                     SRAMQYANLLRQEGFWVEYDLLGRSFKSQMKYADKIGTSYLLVLGENELTTGNANLKNM
                     KTGEQTPLLLDDSFVDSFTNVAMYGMFDGVMDEISF"
     CDS             2906..4669
                     /locus_tag="ctg1_609"
                     /transl_table=11
                     /translation="MKGLKRTHFCGEVSQIGTEAVVCGFVQKVRNLGTLLFIDLRDRTG
                     VVQLAFNETQQPELFAKAETCRGEYVLMAHGTVKERESINHDMKNGNVELVVDDLRILN
                     KAQTPPFEITSDTKVNEELRLKYRYLDLRRAPLQRNLVMRHQIAKAAREYFYANDFIEI
                     ETPMMMKSTPEGARDYLIPSRVHPGKFYALPQSPQIYKQLLMVAGMDRYIQLARCFRDE
                     DLRADRQPEFTQIDLEMSFVDVEDILQMAEGFVHHVFQQVLGREIPLPLPRLSYAEAMN
                     RFGSDKPDTRYGMEIQDISEYVKDCGFGVFTGAIEAGGSVRAIVAKQAAGTLTRKEIDK
                     LTEMVKGIGAKGLAFIRWVEEKPSCSFGKFVGEDKLHEILQALDCQQGDVVLIVADKNK
                     VTLPVLGALRQTVARKLDLIPEGQFNFLWITQMPFFEWDEDNNCWMAMHHPFTMPEDDC
                     LQYLDSAPEKVIAKAFDLVLNGTELSSGSIRITNYELQQKMFQALGLTDEEIEAKFGFL
                     VEAYRFGAPPHGGMGIGLDRLAMVMLGVDSLRDVTAFPKVQNASELMSACPSAVDKENL
                     DILGIAVTETE"
     CDS             complement(4743..5621)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_610"
                     /sec_met_domain="GHMP_kinases_N (E-value: 4.9e-10,
                     bitscore: 36.7, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREIQVRTPAKVNLTLDVVGKRDDGYHSIESVFQAVGIYDALTLT
                     RVDTPGITLSSTNKYLPCNQKNIAYQAAQLFLKHAHRWDGIHIHIEKHIPSQAGLGGGS
                     SDGAAVIAALNWLLGCRMSLQEQCEIAAQVGADVPFFLTGGTMHVSGMGEILEPLPPMP
                     ALPMVIAKGKAGVSTPEAYRRIDQLTDPVHPDTARVIDFLRNGRYWDAIPECGNLFEAA
                     TNLEEVTQIKQIMMDMGAQCALMTGSGSAVFGIFDTGLMAQKCCNALHAVVLYAVTCKT
                     LKHSIRIVSRS"
     CDS             complement(5618..6799)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_611"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.2e-73, bitscore:
                     244.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIEYEKLLSSTIQQIKPSGIRKFFDLAENMEGVISLGVGEPDFQT
                     PWVVRSTAIQTLEKRRIIYSANAGLLDLRREICNYLNRKQGITYDPKTELIVTVGGSEA
                     IDISIRALINPGDEVLIVEPSFVCYAPIVRLAGGVPVPMATRLEDSFKLTPEILRSHIT
                     PRTKLLVLPFPNNPTGAIMTREELEKIAEVLRGTNILVLSDEIYSELTYGRTHCSIAQI
                     EGMQERTILVNGFSKAFAMTGWRLGYVAAPAPIIKQTVKIHQYTIMCSPTISQYAAIQA
                     LQSCDEDVRRMVDEYNIRRRYLVERFNEIGLPCFNPEGAFYVFPCIRSTGMSSEAFCEA
                     LLNQQKVAVVPGNAFGDSGEGFVRVSYAYSLKHLMMALDRIEAFLASGKAGQI"
     CDS             complement(6796..7275)
                     /locus_tag="ctg1_612"
                     /transl_table=11
                     /translation="MNELLHLLKQNARLSNEELGAMLGITPAEVAAQIKKLEEDGIIKG
                     YSVVLNDELANKDTVTAFIELKVTPKRDCGFEDLAKTVMMYDEVESVSLMSGAYDLAVT
                     VTGSSLKVIALFVAQRLSTIDGVLSTATHFVLKRYKEKGIFIEQEPIDERGMVSP"
     CDS             complement(7294..8136)
                     /locus_tag="ctg1_613"
                     /transl_table=11
                     /translation="MLIDCHNHTHNSPDGENESVLERCARAAELGIGVLAVTDHCEVNR
                     FFSLAHYGVEPNGYDTYDFSRDFELSMQENTAAKAHTPAGVKLLCGIELGQATHELALA
                     EHVYADVRLDFVIGSMHQLPGWDDFAFLDYSKVDAAALFHENLQEIARLASTDTYDVLG
                     HITYALRYMAAAGIHLELAPYREELAEIFRIVIAKGKGIEINTSGLRQAYGDTFPNLEC
                     LKLYRDLGGEILTIGSDAHSNLDLGKGIAQGLDIARAAGFTNIAYFEKHEPQFLKLAD"
     CDS             8324..8593
                     /locus_tag="ctg1_614"
                     /transl_table=11
                     /translation="MRAVVTVIGKDNVGILHQVSGICAEYRANVIEVTQSVLQDLFAMI
                     MLVDISAMTTDFAVLSDRMNQLGEELGLSIHTMHEDIFNSMHRI"
     CDS             8612..9970
                     /locus_tag="ctg1_615"
                     /transl_table=11
                     /translation="MLNVYDILETIRMIQDECLDIRTITMGISLLDCIDPDIDRACEKV
                     YEKITTRAKNLVSVGQQIETEYGIPIINKRISVTPIAMLCGACKGGDPVKFAKALQRAA
                     DACGVNFIGGYSALVQKGFSAGDLELIHSIPEALDVTTNLCSSVNIGSSKAGINMDAVA
                     LMGGIIRQSAELTADRQCVGPSKLVVLCNAPEDNPFMAGAFHGVGEPDCVINVGVSGPG
                     VVRAALAKHPDASINEIADIIKKTAFKITRMGQLVGARASEMLDVPFGIVDLSLAPTPA
                     VGDSVAHILEEIGLECCGTHGTTAALALLNDAVKKGGVMASSNVGGLSGAFIPVSEDAG
                     MIAAAENGTLRLEKLEAMTAVCSVGLDMVVVPGDTPAETISAIIADEAAIGMVNNKTTA
                     VRLIPAIGKKEGDILEFGGLFGSGPIMQINRKSPAKFIARGGRIPAPMHSIKN"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 64.4;
                     E-value: 4.3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_616"
                     /sec_met_domain="Radical_SAM (E-value: 1.9e-24, bitscore:
                     84.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGYLHSLESFGAVDGPGIRFVVFLSGCPLRCLYCHNPDTWEQK
                     QTLCMTPPQVMEKIRSERSFLLRGGVTLSGGEPLMQPAFCEELLTLCRQEGFHTAIDTS
                     GSIPLSQSRHAIDLANMLLLDIKDIDPEDCRTLTGKTNENALATLDHCEQTGKEVWIRH
                     VLVPGYTLNPDKLRRLAEKLSGYRCVKRVELLPYHTMGLYKWEALGIPCKLADTPTPTD
                     DEIAMANGFFTKQKTPAAE"
     CDS             complement(10747..12960)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_617"
                     /sec_met_domain="Gly_radical (E-value: 8e-43, bitscore:
                     142.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.7e-278, bitscore:
                     921.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFKSGIWDKEINLRDFIIQNYTPYEGDDSFLAPPTARTRALWDK
                     VLALLEQERKAGGVLDIDEHTISTITSHKCGYIDKELETIVGLQTDAPLKRAIMPFGGI
                     RMVRNSLAAYGRELPPDVENVFKYRKTHNDGVFDVYTDDMKRARHTGIITGLPDAYGRG
                     RIIGDYRRIPLYGVDRLIEDKIAAKKAHDAEPMYGDTVRNLEEMAEQIKALKELKEMAA
                     GYGFDISRPAENTQEAIQWLYFGYLAAIKEQNGAAMSLGRVSTFLDIYAEQDLKSGTFT
                     EEQIQELVDHFIMKLRMVRFLRTPAYDELFSGDPTWVTESIGGMCEDGRPMVTKMSYRF
                     LHTLVNLGPAPEPNLTVLWSHRLPEPFKKFCARISISTSSIQYENDELMRERFGDDYGI
                     ACCVSAMPIGKQMQFFGARANLAKALLYAINDGRDERYEDRLCQGVGQLSDGPLQFDEV
                     YSKFEYVCEWLTKLYINTLNIIHFMHDKYCYERLQMALHDENIIRTSACGLAGLSVVVD
                     SLSAIKYAKVTPIRNAAGIATDFAIEGDYPKFGNNDPRVDELATMVVERFMKRLSRRRT
                     YRNSIPTMSILTITSNVVYGKKTGSTPDGRKAGEPFAPGANPMHGRDTNGCIASMLSVS
                     KIPYAYAEDGISYTFSIIPDALGKNEEDKENNLVALLDGYTREHGHHMNVNVMNRETLI
                     DAMDHPELYPQLTIRVSGYAVNFIKLTREQQLDVIHRTFHTRM"
     CDS             complement(13148..13636)
                     /locus_tag="ctg1_618"
                     /transl_table=11
                     /translation="MLRRDKINYYLDIAETVLERSTCIRRKFGAIIVKHDEIISTGYVG
                     APRGRKNCNDLNYCTRDKLGVPKGQRYELCRSVHAEQNAILSAARADMIDATLYLACHD
                     ARTDQLDGEVEPCSMCKRLIINAGIKQVIVRQTRDAYKIITVSDWVEQDESLTGSSGY"
     CDS             13731..14588
                     /locus_tag="ctg1_619"
                     /transl_table=11
                     /translation="MENLTNISVVQDLARRHGFHFSKGLGQNFLINPTVCPRIAELGNA
                     RPGFGVLEIGTGFGVLTAELAKRADKVVAVEIDQRLLPVLEETLADFDNVKIVPGDIMK
                     IDVAALLRQEFGGLPVAVCANLPYYITSPILMLLLESRLPLTSITVMVQKEAAQRLCAQ
                     VGTREAGAITVGVHYYGEARQLFPVSRGSFMPAPNVDSAVIRIDLHENPHPEGLDEGFF
                     FRMVKAGFSQRRKTLANSLASLLGIPKQAVYAALEQAGLAPAARIEQLTMEQLFALARI
                     LQSA"
     CDS             14766..16991
                     /locus_tag="ctg1_620"
                     /transl_table=11
                     /translation="MIKERTTERLTRGQAGALLLSGVSAFLLTGARFGEFSSPLQVSLA
                     AVVSPLQGVAVLAGSLFASVTQGTLGDAPVLLCALVMIVLSGFVLPRRTSAGMGALAAA
                     AGLSISAGLFFVIGGIDLADLALYLCMAVLAGVAAYFAAEALTAFRPAAGGYSEPNGCA
                     FGVCFLLVTGALGSAQLWICNLGVIFAGFVLLQGAKRYGIAGGTVCGVLASAGLMLCSR
                     ELGDAAAFLALSGMAAGYFADFHKGAVCLLFLAIQGAGQLLLGTDSAAILLLLNLSAGC
                     LLYLALPVEGILEQWLPEVGGEEAPAGFAAVQMDYLAHALAGVRQNAQQIARMLERNGC
                     RETTAQSVCEQVCRSCSRRLECWEERYEETAEAFRCAAAGDGTELPEALQDCARAQTLL
                     VHMQQAQRQAALHRMLSARLTESQGFLFSQMELTEELLGTAGQRLAVSYSRSMTRKVTQ
                     RLEREGYPVHTAVAYRSAEGRLALELYAFADAAPDGGSVRDCLSDALGMELDYTEGRLA
                     GEEVRICLWERPPYGLAVFAAQSSARDEEPPGDSYDQFSDGRGHQYLVLSDGMGSGRRA
                     SLDARLVLSNFRRLIEMGVSMQTAVGMVNHIMLTKSTEETFATLDIARISQETGETLLV
                     KYGAAPTLIQQGQVVTMYQTPTFPIGIVGRPEAHVTRLRLEDSDVIVLMSDGVEDSEYA
                     FVKQKLLAGGSLQQAAQAICCKAQRSAADGRPDDITVLLAQVRRNTD"
     CDS             17213..19153
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_621"
                     /sec_met_domain="Alpha-amylase (E-value: 4.1e-11, bitscore:
                     40.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPDLQKENEFPLSLFLSGKNCKSYLFFGAHTISSKGTQYHCFRV
                     WAPHARSVSLVGDFNRWDRSQTPMHAIGGGVWECCIPRLEQFAAYKYSIKGRDGKIRMK
                     ADPYGAHYETRPATASKIYESSYEWKDDAWRKAKRQRNIYKSPVNVYEVHFNSWRINPD
                     GSFLDYRTFAKQMIPYLQKMSYTHIEFMPLTEYPYDGSWGYQVTGYFAPTSRFGTPDDF
                     RAMVDAFHAAGIGVILDWVPAHFPKDEHGLFEFDGGCCYEYEDVRKGEHFAWGTKVFDY
                     GRPEVCSFLISSACCWFEEFHVDGLRVDAVASMLYLDYDRPDGQWCPNKNGGRENLEAI
                     DFLRHLNEAVFEKFPDALMIAEESTAWPMVTKPTCDGGLGFNFKWNMGWMNDMLSYMSM
                     DPLFRSGNHDKLTFSFFYCFSENYVLPISHDEVVHGKCSMIGKMSGGYDQKFDSYRAFL
                     GYMMAHPGKKLLFMGQEFAQMKEWDYQHQLDWMLLDYPKHNTMLKYTRKLNRFYAEHPP
                     LWERDDSWDGFSWIANDDYQQSVIAFRRFDDKGEELIVVCNFVPVERREYRIGVPYKGS
                     YKLLFNSDATEFGGSGAAEKAVKSEAIPMHGFDNSIALTLAPLSTMFFKPVPYKKRRST
                     KKSAPSKAAQK"
     CDS             19218..20420
                     /locus_tag="ctg1_622"
                     /transl_table=11
                     /translation="MYIKKECVAMLLAGGQGSRLYALTQDMAKPAVPYGGKYRIIDFPL
                     SNCTNSGIDTVGVLTQYQPLVLNDYIGNGQPWDLDKLHGGVHVLPPYQTNAGASWYEGT
                     ANAIYQNMSFIERYDPEYVIILGGDHIYKMDYSKMLQFHKQHQADSTIAVLDVPMEEAS
                     RFGIMTCDEEGRVVDFTEKPKEPKSTLASMGIYIFTWKKLKQYLIENENANSGSKDFGK
                     DIIPAMLAAGERLFAYAFEGYWKDVGTLDSLWEANMDLLSPSVPLDLYDKEWKIYSRNL
                     NMPPQYIGDKAAVENSMISEGSEINGTVDFSIIFSGAVVEENATVKYSIIMPGTVIKAG
                     AVVEYAIVGEDCVIHENAKIGASPETIENRDEWGIAVVGHKVDVSEGKTVLPKQIISDN
                     L"
     CDS             20433..21557
                     /locus_tag="ctg1_623"
                     /transl_table=11
                     /translation="MSANISVMGLIFASMHDSSIIDLTKLRTMGSVPFGGRYRLIDFPL
                     SNMVNSDIDDVGVITKSNYGSLLDHLGSGREWDLSRKNGGLHLLPPFSHVGTGIYRGRL
                     EALDGVWEYVEHSPAEYVVLSDCDIVTTIDYRPMIRAHIESGADITVAYSKGFYDKDVN
                     QNATLLGIGEDGMVDDVMIDPPMRGTGNLCMNTFVLSKSFLKQLVKEKMSRNQYSFSRD
                     VLQDKAAGYRIAAYEHTGYVARLDSLSSYYEANLALLNPENRNGLFKKSAPIYTKIMDN
                     GPVRFGLESDIQNSLIADGCIIEGKVENCVLFRGVKIGKGTVVKNSVIMQNTSIGSKCS
                     LNCVITDKDVEIVDDRVLTGSQSYPLYISKGAKI"
ORIGIN
        1 tgtgcataat gcacaaagac ggtctgtcga aacaatgtaa ctatacaatt ttttattttt
       61 cccgaaaagg ggctttgaca atcccgataa gtatggtata atatagtatg atatactgtg
      121 taaagaaaga tcaaatccgg ctgtctgcac gcaggcagac atggttactg tgccggcaaa
      181 taggggaaag gaatctgata ctatgtcaaa agtaattgca gttacgtccg gcaaaggcgg
      241 cacgggcaaa tcctccatct gttccggatt ggggtatacc cttgcaaagc agggcagcag
      301 aaccctgatc atcgagctgg atttcggtct gcgctgtatt gatatcattt tcggcatgca
      361 gggcaagatc aagtacgacc tgggggatgt gcttcacaac cgggtaaagc ccctggatgc
      421 tgtaacccag gtgcctatgg caagcaactt gaatattctc tgcgcaccga aggacccctt
      481 tgcaagcgca acggtggagc aaatcgtgga tatctgcaag cagatccgaa aatattttga
      541 ctatatcatc atcgacaccg gtgccggcat caactcccat gtattcgata tcgtggaaca
      601 ggccaacacc attctggttg tgaccacgcc ggatcccatc tgcgtgcggg atgcccagat
      661 gatgtccgat gaattctata accgtggcaa taagcgccag cgcctgatta tcaacaaggt
      721 caacaagcgt gccatcggct cggaactggt aaaaagcctg gacgagatca ttgacaccat
      781 cggcgtgcag ctgatcggcg tgatcccgga ggattacgag ctggtcatcg ccaccggcaa
      841 gggtcagccc atcccctcca ctgcgcccag cctggcggca tttgacgcca ttgccaagcg
      901 gctcaagggc gagaacgcac cgctgaccgt gaaaatcaag taacagtctg ctgccactgt
      961 gcagcggtgt ctgacagcat catcgcaaaa agcggtagaa aggaacggac ttatgaacat
     1021 agcattgatt gcccacgact ccaagaagga actgatgatc cagttctgta ttgcatactg
     1081 cggtatcctg tcccgtcaca acctgtgcgc caccggtacc accggcaagc aggtcagcga
     1141 ggctaccggt ctgcacattc agcgatatct gagcggttcc cagggcggcg atcagcagat
     1201 ctgtgcccgt atttcctgca acgagattga tgtgctcctg tttttccggg atcccatcaa
     1261 tcccaagtcc aacgaaccca acgatatgaa cctgctgcgg ctgtgcgacg tacacaacgt
     1321 accggttgcc accaatattg caaccgcaga ggctttgatc ctggcactgg aacggggcga
     1381 cctggattgg cgtgaaatcg gaaatccctc cctgtaaggc actgctgcgg catatgcagc
     1441 cgttgaattg cccccatgcg gggcaattgc tgttttgtgc ggcactgccc ggacaacacc
     1501 aatacttccc gaaaggagct gcgcagggcg caggaaaatt atggctttga atttaaaacg
     1561 acccaacggc acggaggata ttaccccggc aaacatccac aaatggtaca ccgtagagca
     1621 ggtagcccgc agtgtggcgc agtcctatgg cttccgggaa atccgcatcc ccacctttga
     1681 aaacacggag ctgtttcagc gctctgtggg ggagaccacg gacgtggtgc agaaggaaat
     1741 gtacaccgtc atggcaaagg aaacgaagtt tacactcaga ccggagggca ctgccggcac
     1801 tatccgtgcg atgctgcaaa acgggctgct gaatgaggca ctgccccaga aggtgttcta
     1861 tctgctgtcc tgcttccggc atgaacgacc ccaggcaggc agactccggg aattccacca
     1921 gtttggtctg gaaatggcag gaagtgcaga gcctgttgcg gatgcggagg tcatttccct
     1981 ggcaaaggca gttctggata cgctgggtct gaaggggatc cagctgtaca tcaattccat
     2041 cggctgcccc acctgtcggg cggaatacca caaggcgctg cgggcatact ttgaagcccg
     2101 gaaggatcag ctttgcgaca cctgtctgtc ccgattggag aagaatccca tgcggatcct
     2161 ggactgcaag agccctattt gcggagagct tggaaaggac gctccggtga tcctggatta
     2221 cctgtgtgag gactgcaaga cccactttga aaagctccag ggctatctga aggcgatgga
     2281 cattgatttt tccatcaacc ccaagatcgt ccggggtctg gattattaca caaagaccgt
     2341 gtttgaattc gtcaccaccg acatcggcgc ccagggtacc gtatgcggcg gcggcagata
     2401 tgacggactc atcgaggagc tgggtggaca gcatcagcct gccctgggct ttgcaatggg
     2461 gattgagcgg ctgctgctga ccatggagag ccagggctgt gacttcctgg aacccaatca
     2521 ctgcgatctg tacattgcca ccatggatcc ggaaggggtc agccgtgcca tgcagtatgc
     2581 aaacctgctg cggcaggagg gcttctgggt ggaatatgac ctgctgggtc gcagcttcaa
     2641 gtcccagatg aaatatgcgg acaagatcgg cacctcttat ctgctggtgc tgggtgaaaa
     2701 tgagctgacc acggggaatg caaacctgaa gaatatgaag accggagagc agacgcctct
     2761 cctgctggat gacagctttg tggattcgtt caccaatgtt gctatgtacg gcatgtttga
     2821 cggagtaatg gacgagatat ccttttaatg gaacaacgga aaggagcata gtccgcttgg
     2881 gcgggcgaac aggatgatgg atacaatgaa gggcttgaaa cggacacatt tctgcggaga
     2941 ggtaagccag atcggcacgg aggctgtggt atgcggtttc gtgcagaagg tgcgcaatct
     3001 tggcaccctg ctgtttattg acctgcggga tcgtaccggc gtggtacagc tggcattcaa
     3061 cgaaacccag cagccggagc tgtttgcaaa ggcagagacc tgccggggcg agtatgtgct
     3121 gatggcacac ggtaccgtca aggaacggga gagcatcaac cacgatatga aaaacggcaa
     3181 cgtggaactg gtggtggatg atctgcggat cctgaacaag gcgcagacgc ccccctttga
     3241 gatcacaagc gataccaagg tcaacgagga gctgcggctc aagtaccggt atctggatct
     3301 gcgccgggca cccctgcagc ggaacctggt catgcggcat cagattgcca aggcggcaag
     3361 agagtatttc tacgccaacg attttatcga gatcgagacc cctatgatga tgaaatccac
     3421 cccggagggg gcacgggatt atctgattcc ctcccgggtg catccgggca agttctatgc
     3481 tctgccccag tccccccaaa tctacaagca actgctgatg gttgcaggca tggatcggta
     3541 cattcagctg gcacggtgct tccgggatga ggatctccgg gcggaccggc agccggaatt
     3601 cacccagatc gacctggaaa tgtcctttgt agacgtggag gatatcctcc agatggcgga
     3661 gggctttgta catcatgtgt ttcagcaggt gctgggcaga gagattcccc tgcccctgcc
     3721 ccgtctgtcc tatgcagagg ccatgaaccg gtttggctct gataagccgg atacccgata
     3781 cggtatggag atccaggaca tcagcgaata tgtgaaggac tgcggctttg gggtatttac
     3841 cggtgccatc gaagccgggg gcagcgtccg tgccattgtg gcaaagcagg cggcaggcac
     3901 cctgacccgg aaagagatcg acaagctcac ggaaatggtc aagggcatcg gtgccaaggg
     3961 tctggcattc attcgctggg tggaggaaaa gcccagttgc tccttcggga aatttgtggg
     4021 ggaggacaag ctccatgaga tcctccaggc actggattgc cagcaggggg acgtggtgct
     4081 gatcgtggca gataagaaca aggtgactct gccggtactg ggggcactgc gtcagaccgt
     4141 ggcacggaag ctggatctga tcccggaggg gcagttcaac ttcctgtgga tcacccagat
     4201 gcccttcttc gagtgggatg aggacaacaa ctgctggatg gcaatgcacc accccttcac
     4261 catgccggag gatgactgtc tccagtatct ggacagcgcc ccggaaaagg tcattgccaa
     4321 ggcgtttgac ctggtgctga acggcacgga gctttcctcc ggatccattc gtatcaccaa
     4381 ctacgagctg cagcagaaga tgttccaggc gctgggtctg accgacgagg agatcgaagc
     4441 caagttcggt ttcctggtgg aggcataccg gtttggtgcg ccgcctcacg gtggcatggg
     4501 tatcggtctg gatcgtctgg caatggtgat gctgggcgtg gacagcctgc gggatgtaac
     4561 cgcattcccc aaggtgcaga acgccagcga gctgatgtct gcatgcccct ccgcagtgga
     4621 caaggaaaat ctggatattc tgggcattgc cgtaacggaa acggaataag cccaggcaga
     4681 acgataaaac aagcccggaa gcgatggaaa accgcttccg ggcttttgct tgcttcgatt
     4741 ggttagctgc ggctgacgat gcggatgctg tgcttgaggg tcttgcacgt caccgcatag
     4801 agaactactg catgcagggc gttgcagcat ttctgtgcca tgaggccggt gtcaaaaatg
     4861 ccgaacactg ccgagccgct gccggtcatc aaggcgcatt gcgcccccat gtccatcatg
     4921 atctgcttga tctgggtaac ctcctccagg tttgtggcgg cttcaaacag attgccgcac
     4981 tcgggaatgg catcccaata ccgcccgttc cggaggaagt caatgaccct tgcggtatcc
     5041 ggatgcaccg gatccgtcaa ctggtcgatc cgccggtatg cctccggggt ggacacacct
     5101 gctttgcctt tggcgattac catgggcaga gcaggcatgg gcggcaaagg ctccaggatc
     5161 tctcccatgc cggacacatg catcgtgccg cccgtcagaa agaagggcac gtccgccccc
     5221 acctgtgcgg cgatctcgca ctgctcctgc agggacatgc ggcagcccag cagccagttg
     5281 agagcagcga ttaccgcagc tccatcggag ctgccaccgc ccagacctgc ctgggaggga
     5341 atgtgctttt caatgtgaat gtgaatgcca tcccagcgat gcgcatgctt cagaaacagc
     5401 tgagccgcct ggtaggcgat atttttctga ttgcaaggga gatatttgtt ggtgctggat
     5461 agggtgatgc cgggggtatc cacccgagtc aacgtgagtg catcgtaaat gccaactgcc
     5521 tggaagacgc tttcgatgct gtgatacccg tcatcccgct tgcccaccac atccagagtc
     5581 agatttacct ttgccggggt gcgtacctgg atttctctca tatttgacct gcctttccgg
     5641 aagcaaggaa tgcctcgatc cgatccagtg ccatcatcag atgcttgagg gagtatgcgt
     5701 aggacacccg gacaaagccc tcgccactgt cgccgaatgc gttgccgggc accacagcca
     5761 ccttctgctg gttgagcagt gcctcacaga atgcctcact gctcatgccg gtgctgcgga
     5821 tgcaggggaa tacatagaac gccccctctg gattgaagca ggggagtccg atctcgttga
     5881 accgctccac caggtatcgc cgccggatgt tatactcgtc caccatccgg cgcacgtcct
     5941 cgtcacagct ttgcagtgcc tggatggcag cgtactgact gatggtgggg gagcacataa
     6001 tggtatactg gtgaattttc actgtctgct tgatgatggg tgcgggggca gccacatacc
     6061 ccagccgcca gccggtcatg gcaaacgcct tggagaagcc gttcaccaga atggtgcgct
     6121 cctgcatgcc ctcgatctgg gcgatggagc agtgggttct gccgtaggtc agctccgagt
     6181 agatctcatc ggacagcacc agaatgttgg tgccccggag cacctctgcg attttctcca
     6241 gttcctcccg ggtcatgatg gcaccggtgg gattgttggg gaagggtagt accagcagct
     6301 tggtgcgggg ggtaatatga ctgcggagga tctccggggt cagcttgaag gaatcctcca
     6361 gacgggtggc catgggcacg ggtacgcccc ctgccagccg gacgatggga gcatagcaca
     6421 cgaaggatgg ctccacgatc agaacctcgt cccctggatt gatgagggca cggatggaaa
     6481 tatcaatggc ctcggagccg cccacagtaa cgatcagctc cgttttcgga tcgtatgtaa
     6541 tcccctgttt ccggttcaga taattacaga tctcccggcg cagatccagc agtcccgcat
     6601 tggcactgta aatgatccgg cgcttctcca gggtctggat ggcagtactg cgaactaccc
     6661 aaggggtctg gaaatccggc tcgcccaccc ccagactgat gaccccttcc atgttttccg
     6721 ccagatcgaa gaatttccgg ataccggagg gcttgatctg ctgaatggtg ctggaaagca
     6781 gcttttcgta ttctatcacg gtgaaaccat acccctctcg tcaataggct cctgttcgat
     6841 gaagatgccc ttttccttat agcgtttgag gacgaagtgg gtggcagtgg acagcacccc
     6901 gtcaatggtg gacaggcgct gcgccacgaa cagggcaatc accttcaggc tggagccggt
     6961 tacggtaaca gccaggtcat aggcaccgga catgagggat acgctttcca cctcgtcata
     7021 catcatcacc gtcttggcaa gatcctcaaa gccgcagtcc cgcttgggag tcaccttcag
     7081 ttcaatgaag gcagtcaccg tgtccttgtt ggcaagctca tcgttaagca ctacgctgta
     7141 gcccttgatg atgccgtcct cctccagctt cttgatctgt gccgccacct ctgccggggt
     7201 gattcccagc atggcaccca gctcctcgtt ggacagacgg gcgttctgct tgagcaaatg
     7261 cagtagttcg ttcatgtgat aacctcctgt tcatcaatcc gcaagcttta aaaactgcgg
     7321 ttcgtgtttt tcaaagtagg cgatatttgt aaatccggct gcccgggcaa tgtccagtcc
     7381 ctgggcaatg ccctttccca gatccagatt ggaatgggcg tcggaaccga tggtgaggat
     7441 ttctcccccc agatcccggt acagcttcag acattccaga ttggggaagg tatccccgta
     7501 tgcctgccgc agaccggagg tgttgatctc gatgcccttg cccttggcaa tgacgatccg
     7561 gaagatctcc gccagttcct ccctgtaggg ggcaagctcc aggtgtatcc ctgctgccgc
     7621 catataccgg agggcgtagg tgatatgccc cagcacatcg taggtatcgg tgctggcaag
     7681 ccgggcaatt tcctgcaaat tttcatgaaa cagtgcggca gcatccacct tgctgtaatc
     7741 cagaaaggcg aaatcatccc agccgggtag ctggtgcatg gagccgatga cgaaatccag
     7801 ccgcacgtct gcgtatacat gctccgccag tgcaagctca tgggtggctt gtcccaactc
     7861 aatgccgcac agcagcttca ccccggcggg ggtatgagcc ttggcggcgg tgttctcctg
     7921 catggacagc tcaaagtccc tgctgaaatc gtaggtatca tagccgtttg gctccacgcc
     7981 gtagtgggca aggctgaaga atcggttgac ctcgcagtga tccgtcaccg ccagcacgcc
     8041 gatgcccagc tctgccgccc gggcgcatcg ctccaggacg ctttcgtttt ccccgtccgg
     8101 agaattgtgg gtgtgattgt ggcaatctat cagcatagca tctcatcctt tggtgtgggt
     8161 tttctctatt atatcatata tttgcggaaa ggaaaagtag cagcagaaaa aaattgcacc
     8221 ggggcacgga cgaaaaattg tgcaaagggc tttctttttc cttgggcttg tggtatacta
     8281 atatagaacg tcatgtttga aactgaatct ggaggattta catatgagag cggttgtaac
     8341 tgtaatcggc aaagacaatg taggcattct gcatcaggtc agcggcattt gcgctgagta
     8401 ccgggcaaat gtgatcgagg tgacccagag cgtgctgcag gatctgttcg ctatgatcat
     8461 gctggtggac atttccgcta tgaccacgga ttttgccgtg ctgtctgacc ggatgaacca
     8521 gctgggagaa gaactgggtc tgtccattca caccatgcac gaggacattt ttaattccat
     8581 gcaccggatc tgatgggaaa ggactgctga tatgctgaat gtatacgata ttctcgaaac
     8641 catccgcatg atccaggacg agtgcctgga catccgtacc atcaccatgg gcatttccct
     8701 gctggactgt atcgatccgg acattgaccg tgcctgtgaa aaggtgtatg aaaagatcac
     8761 cacccgggca aagaatctgg tgtccgtggg gcaacagatc gagaccgagt acggcattcc
     8821 catcatcaac aagcggatct ccgtgacccc cattgccatg ctctgcggcg catgcaaggg
     8881 gggcgacccg gtgaagttcg caaaggcatt gcagcgtgcg gcggacgctt gtggggtcaa
     8941 cttcatcggc ggttattccg cactggtgca gaagggcttt tccgccgggg atctggagct
     9001 gatccattcc atcccggagg ctctggatgt gaccacaaat ctttgctcct ccgtcaacat
     9061 cggctccagc aaggcaggca tcaatatgga cgcagttgcc ctgatgggcg gtatcatccg
     9121 ccagtctgcg gagctgactg cggatcggca gtgcgtaggc ccctccaagc tggtggtgct
     9181 gtgcaatgca ccggaggata acccctttat ggctggtgcg ttccacgggg tgggagagcc
     9241 ggactgcgtc atcaacgtgg gtgtatccgg ccccggcgtg gtacgggcag cccttgcaaa
     9301 gcacccggat gccagcatca acgaaatcgc tgatatcatt aaaaagaccg cctttaagat
     9361 cacccggatg ggtcagctgg tgggagcacg ggcttccgaa atgctggatg tgcccttcgg
     9421 catcgtggat ctgtccctgg cacccactcc ggcagtgggg gacagcgttg cccatattct
     9481 ggaggagatc ggtctggagt gctgcggcac ccacggtacc acggcggctc tggcgctgct
     9541 caatgacgca gtgaagaagg gcggcgtaat ggcatcctcc aacgtaggtg gtctgtccgg
     9601 tgctttcatt cccgtgtccg aggatgcagg catgatcgct gccgcagaaa acggcaccct
     9661 gcggctggaa aagctggagg ctatgactgc ggtatgctcc gtgggtctgg acatggttgt
     9721 ggttccgggg gataccccgg cggagactat ttctgccatc atcgcagacg aggctgccat
     9781 cggcatggtg aacaacaaga ccacggcggt gcggctgatc cctgccatcg gcaagaagga
     9841 aggggatatc ctggagtttg gcggtctgtt cggcagcggc cccattatgc agatcaatcg
     9901 gaagtccccg gcaaagttca ttgcccgggg cggcaggatc ccggcgccca tgcacagcat
     9961 caagaactga ttccacatac aaacagaacc cctgctgcgg tcattccgca gcaggggttt
    10021 tctgcttagt aaagaatccg tttgccatgg cgatctcgtc atccgtaggc gtcggggtat
    10081 ccgccagctt gcaggggatc cccagagctt cccacttgta cagccccatg gtatgatagg
    10141 gcagcagctc cacccgtttt acgcatcggt agccggacag cttttccgcc agtcgccgga
    10201 gcttgtccgg attcagggta tagccgggca ccagcacatg ccggatccat acctccttgc
    10261 cggtctgttc gcagtgatcc agagtggcaa gggcgttttc gttggttttt ccggtcagcg
    10321 tccggcaatc ctccgggtca atgtccttga tgtccagcag aagcatgttc gccagatcaa
    10381 tggcatgccg ggactgggac aggggaatgg agccgctggt gtcaatggcg gtgtggaagc
    10441 cctcctgccg gcaaagcgtc agcagctcct cacagaatgc aggctgcatc aaaggctctc
    10501 cgccggaaag ggtcacgcct ccccgcagca gaaagctgcg ctcactgcgg atcttctcca
    10561 ttacctgggg cggcgtcatg cacagagtct gcttctgctc ccaggtatct ggattgtgac
    10621 agtacaggca ccggagggga cagccggaca gaaataccac aaagcggatg ccggggccgt
    10681 ccactgcgcc gaagctttcc agggaatgca gatagccggt ggtcatgggg attcctcctt
    10741 ccgggactac atccgggtgt ggaaggtgcg gtggatcacg tcaagctgct gctcccgggt
    10801 cagcttgatg aagttgaccg catagccgct gacccggatg gtcaactggg gatacagctc
    10861 cggatgatcc attgcatcga tcagcgtctc ccggttcatg acgtttacgt tcatatggtg
    10921 tccgtgctcc cgggtgtagc cgtccagcag ggcaaccagg ttgttttcct tgtcctcctc
    10981 gttcttgccc agtgcgtccg gaatgatgga gaaggtgtag gaaatgccgt cctctgcgta
    11041 ggcatagggg atcttggata cggacagcat ggatgcgatg cagccattgg tgtccctgcc
    11101 gtgcatggga tttgctcccg gtgcgaaggg ctcccctgcc tttctgccat ccggggtgga
    11161 gccggttttc ttgccgtata ctacgttgga ggtaatggtg aggatggaca tggtgggaat
    11221 ggaattccgg taggttctcc ggcgggacag ccgcttcatg aaccgctcca ccaccatggt
    11281 ggcaagctcg tccactctgg gatcgttatt gccgaacttg gggtaatccc cctcaatggc
    11341 aaagtcggtg gcgatgcctg ctgcattccg gatgggggtc accttggcat acttgatggc
    11401 ggacaggctg tccaccacca cggaaagccc tgccagaccg caggcggagg tgcggatgat
    11461 gttctcatcg tggagcgcca tttgcagccg ttcgtagcag tacttgtcgt gcatgaagtg
    11521 aatgatgttc agggtgttga tatacagctt ggtgagccat tcacacacat attcaaactt
    11581 actgtagacc tcatcaaact ggaggggccc atccgacagt tgtcccacac cctggcacag
    11641 ccgatcctcg taccgctcgt ccctgccgtc gttgatggca tacagcagcg ccttcgccag
    11701 gttggctctt gccccgaaga actgcatctg cttgccgatg ggcatggcag atacgcagca
    11761 ggcgatgccg taatcatctc cgaaccgttc ccgcatcagc tcatcgttct cgtactggat
    11821 ggaggaggtg ctgatggaga tccgggcgca gaatttcttg aagggctccg gcagccggtg
    11881 actccacagt accgtcaggt tcggctccgg tgcaggcccc aggtttacca gggtatgcag
    11941 gaaccggtag ctcatcttgg tgaccatggg tctgccgtcc tcacacatgc cgccaatgga
    12001 ttcggtgacc caggtgggat cgccggagaa cagctcatca taggcagggg tacgcaggaa
    12061 ccgtaccatc cgcagcttca taatgaagtg atctaccagc tcctggatct gttcttcggt
    12121 aaaggtaccg cttttcagat cctgctctgc gtagatatcc aggaaggtgg acacccgccc
    12181 cagggacatg gcggcaccgt tctgctcctt aatggctgcc agatagccga agtacagcca
    12241 ctggatggcc tcctgggtgt tctctgccgg ccgggaaatg tcgaagccgt agcctgccgc
    12301 catttcctta agctccttca gcgccttgat ctgttccgcc atttcctcca ggttccgcac
    12361 cgtatccccg tacatgggct ctgcatcatg tgccttcttg gcagcgatct tgtcctcgat
    12421 gagccgatcc accccgtaca gggggatccg ccggtaatcc ccgatgatgc gccctctgcc
    12481 gtatgcgtcc ggcaggccgg tgatgatgcc tgtgtgccgg gcacgcttca tatcgtcggt
    12541 gtacacgtca aataccccat cgttgtgggt cttccggtat ttgaatacgt tttccacatc
    12601 cgggggcagt tctctgccgt aggctgccag ggaattgcgc accatgcgga taccgccgaa
    12661 gggcataatg gcacgcttca gaggtgcgtc cgtctgcaag cccacaatgg tttccagttc
    12721 tttgtcgatg tagccgcatt tgtgggaggt gatggtggaa atggtgtgct cgtcaatatc
    12781 cagcacgcct cctgccttcc gctcctgctc cagcagggcg agcaccttgt cccacagcgc
    12841 cctggtacgg gcagtggggg gcgcaagaaa gctgtcgtcc ccttcatagg gtgtatagtt
    12901 ctggatgata aagtcccgca gattgatctc cttgtcccag atgccgcttt tgaatttcat
    12961 ggcttcctcc ttgttccgtg aaccaaatcc aatatcaata tgttgtgtgg attcaccggg
    13021 aatatacccg aagaagcaca acatttgcta tattcactat agcacacttt caacagtctg
    13081 tcaatgtggc attgctccac aaaaactttg actatccggc gcaaaaatgg tatactatga
    13141 aagaacatca atacccgctg ctgccggtca gggattcgtc ctgctccacc cagtcggaca
    13201 cagtgatgat cttatacgca tcccgggtct gacggacaat cacctgcttg atgccggcgt
    13261 tgatgatgag ccgcttgcac atggagcagg gttccacttc cccgtccagc tgatccgtcc
    13321 gggcatcgtg acaggcaagg tacagggtgg cgtcgatcat gtccgcccgg gcggcggata
    13381 aaatggcgtt ctgctctgca tgcaccgacc ggcacagctc atatcgctgt cccttgggaa
    13441 cgcccagctt gtcccgggtg cagtaattca gatcattgca gttttttctg ccccggggcg
    13501 caccgacgta tccggtggaa atgatctcat catgctttac aataatggca ccgaacttgc
    13561 ggcggatgca ggtgctgcgc tccagtacgg tttcggcaat atccaggtaa taattgattt
    13621 tatcacggcg aagcattgaa taccctcctt atgcatcaat agatacatat agtatagcaa
    13681 agtcgggggc aaaatgcaag attggcttgc aagaaaggac aggttatcat atggagaatc
    13741 tgacgaatat ttcagtggtg caggatctgg cacggcggca cggctttcat ttttccaagg
    13801 ggctggggca gaatttcctc atcaacccta cagtctgccc ccggatcgcc gaattgggca
    13861 acgccagacc cggcttcggg gtgctggaga tcggaacggg ctttggggtg ctgacggcgg
    13921 agcttgcaaa gcgtgcggat aaggtggtgg cagtggagat cgatcagcgg ctgctgccgg
    13981 tgctggagga gaccctggcg gactttgaca acgtgaagat cgtgccaggg gatattatga
    14041 aaattgacgt ggcggcattg ctccggcagg agttcggggg gcttcctgtt gcagtatgcg
    14101 ccaatctgcc ctattatatc acttcaccca ttctgatgct gctgctggaa agccggttgc
    14161 ccctcacctc cattaccgtc atggtgcaga aggaagcggc ccagcggctc tgcgcccagg
    14221 tgggtacccg ggaggcaggg gcgatcacgg tgggagtcca ttactacggg gaagccagac
    14281 aactgttccc tgtatcacgg ggcagcttta tgccggcacc caacgtggac tcggcggtga
    14341 tccgcatcga tctgcacgaa aatccccatc cggaggggct ggatgagggc tttttcttcc
    14401 ggatggtgaa ggcaggcttt tcccagcggc gcaagaccct cgccaacagt cttgcctccc
    14461 tgctggggat cccgaagcag gcggtgtatg ctgccctgga gcaggcaggg cttgcgcctg
    14521 ctgcccggat agagcagctg accatggaac agctgtttgc ccttgcccgg atcctgcaat
    14581 cggcatgatc ttcattgccc cggcatttcc caatggaatg ccgccggaac aaccggaatg
    14641 ctgcaagggc ttgcgacagg attccgcctg cctgccgtgg tatactttct gtatcaaagc
    14701 agcatcgcac aaagagcatg cggtgctgtc gcaatgaaac ggatggagaa agtgggcgga
    14761 tacatatgat caaggaacgt acaaccgagc gtctgacacg gggacaggca ggggcattgc
    14821 tgctgtccgg tgtcagcgct tttttgctga ccggtgcccg gttcggggaa ttttcctccc
    14881 ccttgcaggt ctccctggcg gcggtggtgt cccccctcca gggggtggcg gttctggctg
    14941 ggagcctgtt tgcctccgtg acccagggaa ccctggggga tgcaccggtg ctgctgtgcg
    15001 ccctggtgat gatcgtgctg tccgggtttg tgctgccccg gcggacaagt gccgggatgg
    15061 gcgctctggc ggcggcagcc gggctcagta tttccgccgg attgtttttt gtgatcgggg
    15121 gcatcgacct ggcggatctg gcgctgtatc tgtgcatggc agtgctggct ggagtggcgg
    15181 catactttgc cgcagaggcg ctgactgcct ttcgccctgc cgctggggga tacagcgagc
    15241 cgaacggctg cgccttcggg gtatgctttc tgctggtgac cggggcactg ggatccgccc
    15301 agctttggat ctgtaacctg ggcgtgatct ttgccgggtt tgtgctcttg cagggggcaa
    15361 aacgctatgg cattgccggg ggcaccgtct gcggtgtgct ggcttccgcc ggattgatgc
    15421 tttgcagccg ggaactgggg gacgctgctg cattcctcgc cctgtccggt atggctgccg
    15481 gatactttgc ggattttcat aagggtgctg tatgcctgct gttcctggcg attcagggag
    15541 caggacaact gctgctgggg acggattcag cagccatcct tctgcttctg aatctgtcgg
    15601 caggatgcct tttgtatctg gcactgccgg tggagggaat cctggagcag tggctgccgg
    15661 aggttggggg agaggaagcg cccgccggct ttgcggcggt gcagatggac tacctggcac
    15721 atgcccttgc aggggtgcgg cagaatgctc agcagatcgc ccggatgctg gaacggaacg
    15781 gatgccggga aaccaccgcc cagagcgtgt gtgagcaggt atgccgcagc tgctcccggc
    15841 gattggaatg ctgggaggag cgatacgagg aaacggcgga ggcgttccgg tgtgcggctg
    15901 ccggggatgg cacagagctg ccggaggctt tgcaggactg cgcaagggca cagaccctgc
    15961 tggtacatat gcagcaggca cagcggcagg cggctttgca ccggatgctg tccgcccggc
    16021 tgacggaatc ccagggattt ctcttttccc agatggaact gacggaggaa ctgcttggca
    16081 ctgccggaca gcgactggcg gtatcctaca gccggagcat gacccggaag gtgacccagc
    16141 ggctagaacg ggagggatat ccggtacata ctgcggtggc ataccggtcg gcggagggca
    16201 ggctggcgct ggagctgtac gcctttgcgg atgcggcgcc ggatgggggc tctgtccggg
    16261 actgcttgtc cgatgctttg ggtatggagc tggattatac ggagggcagg cttgccgggg
    16321 aggaggtgcg gatctgtctg tgggagcgtc ctccctatgg tctggcggtg tttgcagccc
    16381 agtcctccgc ccgggatgag gaaccgccgg gggacagcta tgaccagttc agtgacggca
    16441 gggggcatca gtatctggtg ctgtccgatg gcatgggctc cggcaggcgt gcttccctgg
    16501 atgcccggct ggtgctgtcc aacttccggc ggctcattga aatgggagtg tccatgcaga
    16561 cggcggtggg catggtgaat catatcatgc tgaccaagtc cacggaggaa acctttgcca
    16621 ccctggatat tgcccggatc agccaggaaa ccggcgagac cttgctggtg aaatatggag
    16681 cagcccctac tctgatccag cagggacagg tggtgaccat gtaccagacc cccaccttcc
    16741 ccatcggcat cgtgggcagg ccggaggcgc atgtgacccg actccggctg gaggattcgg
    16801 atgtgattgt gctgatgtcc gacggggtgg aggacagcga gtacgccttt gtcaagcaga
    16861 agctgttggc aggaggctcc ctccagcagg ctgcccaagc catctgctgt aaggcacagc
    16921 gcagtgcggc agacggcaga ccggacgata tcacagtgtt gctggcgcag gtcagaagga
    16981 acacggacta agaaggcggc atcagccgcc ttctttatgc cttgcagaat tttgtgaaaa
    17041 atatacgagg agtcaaggcg ttttccacgt gattttttgc gattttgtac aatatgcata
    17101 aaatggacgg ttgattctag gcggagtata tgaacttttt tggatgtgcg cagaaatact
    17161 tgaatccagg gcgggaatct gttaaaatgt aagcataggg gagggtgata ctatgattcc
    17221 ggatctgcaa aaagaaaatg aatttccgct gtctttgttt ttgagcggga aaaattgcaa
    17281 gtcctattta tttttcggcg cacacacgat atccagcaag ggtacacagt atcattgctt
    17341 ccgggtctgg gcgccccatg cccgatccgt ttccctggtg ggagatttca accgctggga
    17401 cagaagtcag acccccatgc acgccatcgg gggcggcgta tgggaatgct gcattccccg
    17461 gctggagcag ttcgctgcct ataaatacag catcaagggc agggacggca agatccgtat
    17521 gaaggcggat ccttacggag cgcattatga gacccggcca gccactgcct ccaagatcta
    17581 cgagagcagc tatgaatgga aggatgatgc ctggcgcaaa gccaagcggc agagaaatat
    17641 ttacaaaagc ccggtgaatg tgtacgaagt acattttaac tcctggcgca tcaatccgga
    17701 cgggagcttt ctggattacc ggacctttgc aaagcagatg atcccgtatc tgcaaaaaat
    17761 gtcttatacc catattgagt tcatgcccct gacggagtat ccctacgacg gctcctgggg
    17821 ctatcaggtc acgggctatt tcgcccccac ctcccggttt ggtacgccgg atgatttccg
    17881 tgccatggtg gatgcgttcc atgctgccgg catcggggtg atcctggact gggtaccggc
    17941 gcacttcccc aaggatgaac acggcttgtt cgagtttgac ggtggatgct gctacgaata
    18001 cgaggacgtg cgcaaggggg agcatttcgc ctggggcacc aaggtgttcg attacggcag
    18061 gccggaggtg tgctccttcc tgatctccag cgcatgttgc tggtttgagg aatttcacgt
    18121 agatggtctc cgggtggatg cggtggcatc catgctgtac ctggattatg accggccgga
    18181 tggtcagtgg tgccccaaca agaacggggg cagggagaat ttagaggcaa ttgattttct
    18241 gcggcatctg aatgaagcgg tgtttgaaaa gttcccggat gcgttgatga tcgccgagga
    18301 atccaccgcc tggcccatgg tcaccaagcc cacctgcgac gggggtctgg ggtttaactt
    18361 taaatggaat atgggctgga tgaacgatat gctcagctat atgtccatgg atcctctgtt
    18421 ccgctccggc aaccacgata agctgacctt ctcgttcttc tactgttttt ccgaaaatta
    18481 cgtgctgccc atttcccacg atgaagtggt gcatggcaaa tgctccatga tcggcaagat
    18541 gagcggcggc tacgatcaaa aattcgactc ctaccgggcg tttcttggct atatgatggc
    18601 gcatccgggc aagaagcttc tctttatggg acaggagttt gcccagatga aggagtggga
    18661 ttaccagcac cagctggact ggatgcttct ggattacccc aagcacaaca ccatgctcaa
    18721 gtacacccgg aaattgaatc ggttttatgc ggagcatccg cccctgtggg agcgggacga
    18781 ctcctgggat ggattcagct ggatcgccaa tgacgattat cagcaaagcg tcattgcctt
    18841 ccgccggttt gacgacaagg gtgaggagct gatcgtggtg tgcaactttg tgccggtgga
    18901 gcggcgggaa taccggatcg gtgtgcccta taagggcagc tataagctgc tgttcaattc
    18961 ggacgccacg gaattcggcg gctccggcgc agcagaaaaa gccgtcaaat ccgaagccat
    19021 ccccatgcat ggctttgaca acagcattgc gctgacgctg gcacccttgt ccaccatgtt
    19081 cttcaagccg gtgccgtata aaaaacgcag atcgactaag aaatccgcac cgtccaaagc
    19141 ggcgcagaaa tagaagtttt accaacgaat gcagagagga gtggattttt cccttccgga
    19201 aaaatcgagt atgaattatg tacattaaaa aagaatgtgt agcaatgctc ctggcgggcg
    19261 gacaaggcag ccgcttgtat gcgctgaccc aggatatggc aaagccggct gtaccctatg
    19321 gcggcaagta ccggatcatt gattttcccc tttccaactg caccaattcc ggcatcgata
    19381 cggtgggcgt gctgacccag taccagcccc tggtgctgaa cgactacatc ggcaacggac
    19441 agccctggga tctggataag ctgcacggcg gcgtacatgt gctgccccct taccagacca
    19501 atgcaggggc atcctggtac gagggtactg ccaacgccat ctaccagaat atgagcttta
    19561 tcgagcgcta tgacccggag tatgtgatca ttctgggcgg cgatcacatt tacaagatgg
    19621 attactccaa gatgctccag ttccacaagc agcatcaggc ggacagcacc atcgccgttc
    19681 tggacgttcc catggaggag gcttcccggt tcggcatcat gacctgcgat gaggaaggca
    19741 gagttgtgga ctttacggaa aagcccaagg aacccaagtc cacgctggca tccatgggta
    19801 tctacatctt cacctggaag aagctcaagc agtatctgat cgaaaacgag aatgcaaact
    19861 ccggctccaa ggatttcggt aaggatatca tccctgcaat gctggcagca ggggagcggc
    19921 tgttcgctta tgccttcgag ggctactgga aggacgtggg gacgctggac agcctgtggg
    19981 aggcaaatat ggatctgctg agtcccagcg tgcctctgga tctgtatgat aaggagtgga
    20041 agatctactc ccggaacctg aatatgcccc ctcagtacat cggggacaag gcggcggttg
    20101 aaaattccat gatctccgaa ggcagcgaga tcaacggcac cgtggacttt tccatcatct
    20161 tctccggcgc tgtggtagag gagaacgcta ccgtcaagta cagcatcatc atgcccggca
    20221 cggtcatcaa ggcaggtgct gtggtggaat acgccatcgt aggtgaggac tgcgtgatcc
    20281 acgagaacgc taagatcggc gcaagtccgg agaccatcga gaaccgtgac gaatggggca
    20341 ttgcagtcgt aggtcacaag gtggatgttt ccgaaggaaa aaccgtactg cccaagcaga
    20401 ttatatctga caacctgtaa ggagatgtga ctatgagtgc aaatattagc gtaatgggat
    20461 tgatttttgc aagtatgcac gattcctcca tcattgatct gaccaagctc cgcaccatgg
    20521 gctccgtgcc ctttggggga cggtaccggc tgatcgactt ccccctgtcc aatatggtca
    20581 attccgacat tgacgacgtg ggagtcatca caaaatccaa ctacggttcc ctgctggatc
    20641 accttggctc cggccgtgag tgggatcttt ccagaaagaa cggcggtctg catctgctgc
    20701 ctcccttcag ccatgttggc accggtattt accggggcag actggaagcc ctggacggag
    20761 tgtgggagta tgtagagcat tctccggcag aatatgtggt gctgtccgac tgcgacattg
    20821 tgaccaccat cgactaccgg cccatgatcc gtgcgcacat cgaaagcggt gcggatatta
    20881 ccgtagcata ctccaagggc ttctacgata aggacgtgaa ccagaacgcc actctcctgg
    20941 gcatcgggga ggacggcatg gtggacgatg ttatgatcga tccgcccatg cggggcaccg
    21001 gcaacctgtg tatgaacacc tttgtgttga gcaaatcctt cctcaagcag ctggtcaagg
    21061 agaaaatgag ccggaatcag tacagcttca gccgggacgt gctgcaggac aaggcggcag
    21121 gctaccggat cgccgcttat gagcatacgg gctatgttgc ccggctggac agcctgtcca
    21181 gctactatga ggcgaatctg gcactgctga atccggaaaa ccggaacggt ttgtttaaga
    21241 aatccgcccc catctacaca aagatcatgg acaacggccc ggttcggttc ggtctggagt
    21301 ccgacatcca gaactccttg attgcggatg gctgtatcat cgagggaaag gtggaaaact
    21361 gcgtactgtt ccggggcgtg aagatcggta agggcaccgt ggtcaaaaac agcgtcatca
    21421 tgcagaacac ctccatcggc agcaagtgca gcctgaactg cgtgatcacc gacaaggacg
    21481 tggaaatcgt ggatgaccgg gtactgaccg gttcccagag ctatccgttg tatatcagca
    21541 agggtgcgaa gatttaattg caggagggat gatccgtatg aatattttgt ttgcagccag
    21601 tgaggcattg ccctatgtag cgtccggcgg tctggcggat gttgccggct ctctgccctc
    21661 cgctattgtg aaaaagggac atgactgtcg ggtcgtgatc cctctgtaca agtccatttc
    21721 tgcggaaatg cgtgcttctc tgacctttct gaccaatatt accgtggacg tttcctggcg
    21781 gaagcagtac tgcggcattt tcaccggcat ttacaagggt gtgacctatt attttatcga
    21841 caatgagtac tacttcggca gagacggcat ctacggcttc tatgacgact gcgagcggtt
    21901 tgtattctac agccgtgcag tgctggaaat gatccgctgt atcgacttca agccggacat
    21961 cattcacgcc aacgactggc aggctgccat gatcccggtg tactaccaga ttttctacnn
    22021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    22921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
//
