LOCUS       NZ_HF545617.1          22201 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_HF545617.1 Ruminococcus bicirculans (ex Wegman et al. 2014)
            strain 80/3 chromosome II, complete sequence.
ACCESSION   NZ_HF545617
VERSION     NZ_HF545617.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:40:07
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22201
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..990
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="VIISSVIMISFVAFAPQESAKTYVNVITASAADLMTKPVLIKRQA
                     YSNKIEAGVKNLTSFSSKTTFEVYVNGRYVRKYTWQALKKDNYINITNDGKLYLKASTK
                     YKVTVKAVNGSAKSESSVLNVKTAAKTYYYIDKNVQLYSFKNGRFKKSSKTKASVAVSG
                     TLTTDKNKRVAGQSKNIGGANYVLINEGDHKGKYVKVGKGVKRTPERKARIKTAVDYAA
                     SMNGGRYVWGGTKYKATDCCGLTMQAYRKAGVNMYNSVYSQAKMGKAVSLKNIEAGDLI
                     ICNNYGHVAMYIGGGKIVHAMSTYYGIRIQPLANIKYCGKINTIRRIL"
     protocluster    1..22201
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8578:12201]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8579..12201
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..22201
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22201
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1032..1193
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MAESNRAEHQHKVEETPSRAILRHNKLSNNCIGKFSNVNVGAGAL
                     DSPILFAR"
     CDS             1447..2250
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MLKCLSVAGSDCSGGAGIQADLKAFSANETFGMSVITSVVAENTT
                     RVLSVFNVPVEEIQKQIDAVFEDIHVDAVKLGMLPTAEIISAVADKLNEYKPSIIVCDP
                     VMVATSGDALSEGGTVSTMREKLFPIVTLLTPNIPEAEAISGLEIKNENYMEKAARIIM
                     DMGVKNVLVKGGHLTGDAVDYLCTPEGVHKLACKRVDSPNTHGTGCTLSSAITANLAHG
                     MDMLSAVTKAKNYITEAIEKSFTVGKGHSPVNHFYDYYDLKGTVL"
     CDS             2247..3560
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MRNYKTQMEAAKKGIVTPEMETVAKKENMDVNELMALVAAGQVAI
                     PANVNHTALSAEGIGKGLKTKINVNLGISGDAKNYDIEMQKVDMAIKFGAEAIMDLSNY
                     GKTNTFRKELVAKSPAMIGTVPMYDAIGYLDKDLLEISAQDFLKVVKAHAEEGVDFMTI
                     HAGINRRAIEAFRREGRKMNIVSRGGSLLFAWMMMTGNENPFFEYYDEVLEILREYDVT
                     ISLGDALRPGCLADASDAAQISELIELGNLTKRAWEKDVQVMVEGPGHMAMNEIAANMI
                     MEKKICHGAPFYVLGPLVTDIAPGYDHITSAIGGAIAAASGADFLCYVTPAEHLRLPDV
                     DDVKEGIIASKIAAHAADIAKGVKGARDIDDKMAAARHKMDWDEMFEIALDGEKARRFF
                     EQTPPADRHTCSMCGKMCAVRTTNMILEGKEVKFCSEK"
     CDS             3882..4403
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MKKTNIHKLVFAAVLVALAVVGSLISFPIGASKCAPVQHLVNIIG
                     AVFLGPAWAVGVGFTAALLRNLLGLGSLLAFPGSMVGAFVAGMLYKYIKKLPAAYVGEL
                     FGTSVLGGLLAYPVARFLVGAPAAAITVYILPFFVSCAGGTVLAIVIVTALKKAKVFDN
                     FLGFSKEVRA"
     CDS             4403..5221
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MGTIIESCAKAADKVRDICPLVHCITNYVTVNDVANCILAIGASP
                     IMADDIAEAADITSISKALVINMGTLNARTVESMVAAGKKANELGVPVVFDPVGAGASN
                     FRNETAKRILENVKISILRGNLSEMSYLAGLEVSTKGVDTSEADEKNDPVSVAKKTAAK
                     YNCVAAITGAVDTITDGKRVARISNGHPYLSKVTGTGCMTTGLVGSFAGACDDMYTAAV
                     TGIASMGIAGEFAYENAGEIGSGSFHISIIDAISKMNSQVFAAKAKIEEV"
     CDS             5362..5832
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_7"
                     /sec_met_domain="Acetyltransf_1 (E-value: 7e-16, bitscore:
                     53.9, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVRFACEKDIPQMNSLLYQVERVHQQGRPDLFKEGAKKYTDNEL
                     KDMLKDKTKPIFAAVDENDVMKGYAFCVFQEHKGDNVLTDIKTLYIDDLCVDENCRGQH
                     IGSVLYEAVKKFAKEQGCYNVTLNVWECNPSARKFYEKAGLKPYKTGMEVIL"
     CDS             5855..6496
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MDKSKIDYTLYLCTDRGLMSCETIEQSVEEGVKGGCTVIQLREKD
                     CTSREFYELAVRVKKITDKYNVPLIINDRLDIAQAVDCAGVHLGQSDMPCAVARKILGE
                     DKIIGISAATLEEAKKAQVDGADYLGVGAMYATNTKTDARAVTKEQLVEIRAAVDIPIV
                     IIGGVNQKTVPNFKGMGIDGAAVVSAVVSQPDIEKAAKDLRELCEDCFGR"
     CDS             6695..8113
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MKKTKIVCTIGPSTDDENIMRELMKNGMDVARFNFSHSDHSVHKA
                     RFETVCKLREELGVNIATLLDTKGPEVRLKNFKDHKPVTIKDGDTFTLTTREVEGDETI
                     CSITFPQLPKDVSVGTRILINDGNIELKATRVDNTDIVCEVIHGGVVSDHKGINVPDVN
                     LSMPYISDADMADLEFGAKMGFDYIAASFVRTGADVIYLRKFTQSLGWFNPRIIAKIEN
                     AQGVANIDEILDAADGIMVARGDMGVEIPFEQIPAIQKELIRKAYNAGKNVITATQMLE
                     SMITNARPTRAEITDVANAIYDGSSAIMLSGETAAGKYPVEAVKTMSLIAETTEKDIDY
                     ISRFKKRADERNSSITDAISHATVTTAHDLNAVAILTVTKGGTTARTLSKFRPNCPIIA
                     LTTDDTTYHQLSLSWGIRAGVIEEKTNTDELIRHALERSVELGYLKKGDLVVITAGVPL
                     GMSGTTNLLKVERA"
     CDS             8579..10657
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_10"
                     /sec_met_domain="Gly_radical (E-value: 1.2e-13, bitscore:
                     46.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.3e-287, bitscore:
                     948.1, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERQFYDEWEGFKPGRWSNTSINLRDFIQKNFTPYDGDDSFLTGP
                     TEATTKLWEQVMELSKKEREAGGVLDMDTKIVSTITSHGPGYLNKDLEKIVGFQTDKPF
                     KRSLQPFGGIRMAMNACEQNGYTVDPEVVKIFTEYRKTHNQGVFDAYTPEMKLARHAAI
                     ITGLPDAYGRGRIIGDYRRVALYGIDYLVEDKKDQLATSLVRMTSKNIRLREELSEQIR
                     ALGELKKLGEIYGYDISRPAKNAKEAIQWLYFGYLAAVKEQNGAAMSLGRTSTFIDIYI
                     KRDMDRGILTEQEAQELVDHFIMKLRLVKFARTPEYNSLFSGDPTWVTESIGGVSIDGV
                     PMVTKTSFRYLHTLENLGPAPEPNMTVLWSTKLPLNFKKFCAKTSIKTSAIQYENDDLM
                     RVTHGDDYAIACCVSSMRIGKEMQFFGARANLAKCLLYAINGGVDERLKIQVGPKYRPV
                     TGDYLDYDDVMAKYDDMMEWLAGLYVNTLNVIHYMHDKYSYERVQMALHDRDVKRYFAT
                     GIAGLSVVADSLSAIKYAKVKCIRDEDGIVTDYEVEGDFPKYGNNDERVDKIAVDLVRT
                     FMDKIRKHHTYRDGVPTMSILTITSNVVYGKKTGSTPDGRKIGVPLAPGANPMHGRDTH
                     GASASLSSVAKLPFRHAQDGISNTFSIIPDALGKDDKVFMGDLDIESIAKELNEDGV"
     CDS             10647..10874
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MGFNVKKDEDEAQVNELVDVIDRLMMGGQGHLTIDIDETEEGLNV
                     KTYSTSDCGGDGKTACCQPTEEDAVDRDED"
     CDS             10950..11201
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_12"
                     /sec_met_domain="Gly_radical (E-value: 2.4e-26, bitscore:
                     87.7, seeds: 99, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANFEPTEAQIDNLIGLLDGYAEKGGHHLNVNVLNRETLLDAQAH
                     PEKYPQLTIRVSGYAVNFVKLTKEQQDDVISRTFHKSL"
     CDS             11458..12201
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 80.6;
                     E-value: 4.3e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_13"
                     /sec_met_domain="Radical_SAM (E-value: 7.6e-34, bitscore:
                     112.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGFIHSTESFGTVDGPGIRFVIFFQGCPMRCLYCHNPDTWKIGT
                     GTKRTVESLLAEYDSVKEFMKNGGITCTGGEPLVQIDFVTELFEKAKEKGIHTCLDSSG
                     ITFTPDSTEKFERLCKCTDLVMLDIKHIDREEHKKLTGHYNDNILAFAKFLSEYGVPIW
                     IRHVVVPGITDKEEYLFRLGEFISQLKTLKALDVLPYHTMGKVKYEQLGIDYPLGDTPP
                     LDKEDAVKARDVIMRGLKAALKKRK"
     CDS             12463..12960
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MPKNLFQEIVFTVLMVFVMVYAMICYNIALNMGGMSNAVFLKAFH
                     ELVIMAPIAFVLDFFAVGKIAKKKAFSIVDVRKDNPFHLVLAISVISVIFMCPLMSLAA
                     TLLFKDAGREVIAVWLETTVMNFPMALCWQLFFAGPIVRFVFGLIFREREQKSEAVSAA
                     AE"
     CDS             13109..14188
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_15"
                     /sec_met_domain="GATase (E-value: 3.7e-48, bitscore: 159.1,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQKAYLILENGTIFEGKSFGAAGEAIGEIVFTTAMTGYLETLTDP
                     SYYGQIVVQTFPLIGNYGVIPEDFESECPHVKAYIVRDWCQEPSNFRCEGDLDTFLKQH
                     NIVGLYGIDTRQLTKIVRESGVMNGKIVPEGSSFGLTDLKNYTIVEAVKNTTCSEEKTF
                     EPEGEVKRKVVLYDFGAKHNIGRELVKRGCEVTVVPAYTKAERIKELAPDGIMLSNGPG
                     DPAENVEIIEELKKLSEMKIPTFGICLGHQLLALAHGAMTHKLKYGHRGANQPAENTET
                     GRVYITSQNHGYAVENDSLPEGEAKVLYVNANDGTCEGIRYLNEPAFSVQFHPEACGGP
                     HDTDFLFDEFIELIDTNKK"
     CDS             14510..18565
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CPSase_L_D2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_16"
                     /sec_met_domain="CPSase_L_D2 (E-value: 1.1e-77, bitscore:
                     255.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPLNKDIKRVLVIGSGPIVIGQAAEFDYAGTQACRALKQEGLEVI
                     LINSNPATIMTDNAMADKIYIEPLTLETVKRVIKKERPDSLLSTLGGQTGLTLSMQLAK
                     EGFLDKYNVKLLGANPETIDKAEDRQMFKDTMESIGQPCIPSKVVNTVEDAVDFANQPG
                     IGYPLIIRPAFTLGGTGGGIVNDEEELKEITRNGLYLSPITQVLVEKCIAGWKEIEFEV
                     MRDAKGNVITVCSMENFDPVGVHTGDSIVIAPAVTLADKEYQMLRSAALKIIDTLKVEG
                     GCNCQFALNPDSFEYAVIEVNPRVSRSSALASKATGYPIAKVAAQIAIGYTLDEIKNAV
                     TGKTYACFEPALDYVVVKLPKWPFDKFVYAKRELGTQMKATGEVMAIGSTFEQAIMKAV
                     RGAEIGHDCLISPKMLDLDDKTIHDRLSDCTDERLFVVYEALRRGVSVDEIHSISKIDE
                     WFLYKLCKLIDMEKTLKNDFNEETYLEAKKIGYTDKVIEKITGKKIEKPVHAVFKMVDT
                     CAAEFAAMTPYFYSTYDNEDEASEFIANRGHDRKTVIVFGSGPIRIGQGIEFDYASVHC
                     VWALKEKGYDVVIVNNNPETVSTDFDTADRLYFEPLTDEDVMNIIRVEKPVGVVVAFGG
                     QTAIKLTKHMAEHGVNILGTPPDAIDAAEDRERFDELLEQLKIKRPQGFTVMTCDEALE
                     VANKIHYPVLMRPSYVLGGQNMIIAFNDDDIKEYMAIILDQGIENPVLIDKYLMGTELE
                     IDAICDGEDILIPGIMEHIERTGIHSGDSIAVYPAWNVSDSLINRIIECSKKLAIALNT
                     KGLVNIQYIAYHDEIYVIEVNPRSSRTIPYISKVTGVPMVDLATKCMLGEKLKDMGYGT
                     GLYRNSPYVAVKVPVFSFEKLIGVDNHLGPEMKSTGEVLAVSNSLEESLYKGLTAAGYK
                     LGKKGGVFITVRDSDKGEIPQTAKMFADLGFKIYATNGTAKVLHEHGIDAEVVAKIHEN
                     EDNNTLTLIESGKIAYVISTSSKGRIPTRDSVKIRRKTVEWNIPCLTSIDTANAIAASI
                     RSKYTESTTEIVDINNMRTEKQTFEFTKMQGCGNDYIYFNCFDQRIDNPEGLALNLSDR
                     HFGIGGDGVILICRSKVADAKMRMFNLDGSEGKMCGNGIRCVAKFMRDNGIVDKDEMTI
                     ETLSGIMTVSLIRHYGEVSGATVNMGKAILAPHLVPVELEPDENGRVVDRKVNIAGNDY
                     NITCVSMGNPHAVVFMNNVDSLDIDKVGPEFEHDKIFPERVNAEFIKVIDDHTLKMRVW
                     ERGSGETWACGTGACAAAVAAVLNGFCKKDEEISVILKGGTLKIRYTDEAVYLTGDAVT
                     VFSGHIVM"
     CDS             18696..19901
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_17"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-40, bitscore:
                     134.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSINENFLKLEKNYLFINIAKKVKAFTEAHPEADIIRMGIGDVT
                     QPIAKCVVEAMKKGADEMGVKETFKGYEDSGAGYDFLKEAVAGYYKSFGVDIPADDIRI
                     NDGAKSDCGNIVDIFGDDNVVLITDPAYPVYVDTNLMNGRKVIYADSNEENNFAAMPDE
                     NVKCDIIYLCSPNNPTGSVYTKEQLKVWIDYAKKNNAIIIYDSAYEAFITEKDVPRSIF
                     AVEGAKECAIEMCSLSKTAGFTGMRCGYTVIPHELVVKASDGSEVSIAQLWGRREGSKF
                     NGVSYPVQCAAAAVFTEEGQKQTRANIEYYQNNAKVMASTLDELGIKYTGGKNSPYIWL
                     KCPNNMGSWEFFDYLLENANVVGTPGAGFGKNGEGWFRLTAFGDKDRTVEAMERIKKLL
                     SK"
     CDS             complement(20183..21001)
                     /locus_tag="ctg2_18"
                     /transl_table=11
                     /translation="MYKQIYPVIGDEKNLPFYVVGLGLESWQFPIKRADGYEYPQIFLS
                     RSGEGEVIINGETTKIPPDTVFYIPPFCPHEYHALSDAWYLDWIAFSGSQVIPLLEQWK
                     LNKFTAIQGVDMDRLRRIITRIYYTLKSDKLYGNHYASAQLYDFLIEYRKIADNRLSSF
                     YTAQSVALADVLQYIEEHYPEQIKLNELAKIAGVSEQHLCRLFKKNFQLRPMEYLAQVR
                     VQHAKDLLVYSNKTIGEISDETGFQDGSYFSVVFKRYENMTPGEYRRIKV"
     CDS             complement(21067..21423)
                     /locus_tag="ctg2_19"
                     /transl_table=11
                     /translation="MDYLWAFLIGGLFCAIGQVLMDFTKLTPARILVAYVTGGVLLGAL
                     GLYKPLIDLSGCGATVPLTGFGYLLYNGVREQIDKIGFLGIFTGGLTASAAGITAAMTF
                     AFIFSLFFKSSAKE"
ORIGIN
        1 gtgataattt catcagttat aatgataagc tttgtggcat ttgcaccgca ggaatccgct
       61 aagacttatg tgaatgttat aacagcttct gccgctgact tgatgacaaa acctgttttg
      121 ataaaaagac aagcgtattc aaacaaaata gaagcaggag taaaaaatct caccagcttt
      181 tcatcaaaga ctacatttga ggtctatgta aacggacgct atgtaagaaa atatacatgg
      241 caggcactta aaaaggataa ctatataaat ataaccaatg acggcaagct ttatcttaaa
      301 gcttccacaa aatataaagt caccgtcaaa gcggtaaacg gcagtgccaa gtcagagtca
      361 tcggtcctca acgtaaagac agcagcaaaa acatactatt atatagataa aaacgttcag
      421 ctttatagct ttaaaaacgg taggttcaag aaatcctcaa aaacaaaagc ctctgtggct
      481 gtgtcgggta ctctcactac cgataaaaat aagcgtgtgg caggtcagag caagaatatc
      541 ggcggagcaa attatgtcct tatcaatgaa ggcgatcata agggtaagta cgtcaaggta
      601 ggaaaaggtg tgaagcgtac acctgagaga aaagcaagaa taaaaacagc cgttgattat
      661 gccgcaagca tgaacggcgg aagatatgtc tggggcggaa caaagtataa ggcaacggac
      721 tgctgtggat tgacaatgca agcctataga aaagccggtg ttaatatgta taacagcgta
      781 tattcgcagg cgaaaatggg aaaagcagtg tctttgaaga atatagaagc aggagacctg
      841 ataatctgta ataactatgg ccatgtagca atgtatatag gcggtggaaa aatagtccat
      901 gctatgagta catattatgg gatcagaata cagcctcttg caaatatcaa gtattgcgga
      961 aagataaaca ctatcaggag aatactgtag taagtgagga gcagagctaa gtgaggagtg
     1021 aggagtgagg aatggcggag tcaaaccgag ctgaacacca acacaaagta gaggaaacac
     1081 cgagcagagc gatcttgcgg cataacaaac tgtcgaataa ctgtatcggc aaattttcaa
     1141 atgtaaatgt aggggctggc gccctcgaca gcccgatttt gtttgctcga taatacttgc
     1201 gatatctaca caatttttcc ttgacaatct cgctgaccag tgttataata aaaaagcaga
     1261 aaaactgcga aaaaatcgaa taaagtttgc agggggaccc aagcaaaaag ctgggttgag
     1321 aaggtaaaac ctgacccttt gaacctgttg gtcaatacca gtgtaggaag caatttgtgt
     1381 aaattttacc tcctgcattg tcaggaggtt ttttgtttcc ccttttccat aagaaaggaa
     1441 taaagtatgt taaaatgttt gtcagtggca ggctcggatt gctccggtgg cgcaggtata
     1501 caagccgacc ttaaagcctt cagcgctaat gaaactttcg gcatgagcgt tattacctct
     1561 gtcgtcgctg aaaatactac ccgtgtgctg tctgttttca acgtacccgt tgaggagata
     1621 caaaaacaga tagacgcagt gtttgaggat atccacgtcg atgccgtaaa actcggtatg
     1681 ctcccaactg ccgaaattat ttcagcagtt gcggataagc ttaatgagta taaaccaagt
     1741 attatcgtct gcgatcccgt catggtcgct acaagcggcg acgctctctc tgagggcgga
     1801 actgtttcca ccatgaggga aaagctcttt cctatagtta cgctccttac accgaatatc
     1861 cccgaagccg aagctatctc aggcttggag ataaagaatg aaaactatat ggaaaaagcc
     1921 gcaaggataa taatggatat gggcgtaaaa aacgtcctcg tcaaaggcgg tcatctcact
     1981 ggcgacgctg tggattatct ctgtacccca gagggtgttc ataagcttgc ctgcaagcgt
     2041 gttgattcgc ctaataccca tggcactggc tgtactttgt catctgccat aactgcaaac
     2101 cttgcccacg gtatggatat gctctccgct gtaacaaagg cgaaaaacta tatcaccgag
     2161 gcaatagaaa aatcattcac agtgggcaaa ggacatagcc ccgttaatca cttttatgac
     2221 tattacgatt tgaaaggaac tgttctatga gaaattataa aactcaaatg gaagccgcta
     2281 aaaagggtat cgttacccct gaaatggaaa cagtggctaa gaaagaaaat atggacgtaa
     2341 acgagcttat ggctcttgtt gcagcaggtc aggtggcgat ccctgccaac gtaaaccata
     2401 ctgctctctc tgccgagggt atcggtaaag gtcttaaaac taagataaac gtaaatctcg
     2461 gtatctcagg ggacgctaag aattatgaca ttgagatgca gaaagtggat atggctatca
     2521 agttcggcgc tgaagctatc atggatctgt caaactacgg caagaccaat acattcagaa
     2581 aagagctagt agcaaaatcg cctgccatga taggcactgt tcctatgtat gacgctatcg
     2641 gctaccttga taaagacctc cttgagatat cagctcagga ctttcttaaa gtagtaaaag
     2701 cccatgcaga agagggcgtt gactttatga ctatccacgc aggtatcaac agacgtgcaa
     2761 tcgaagcttt cagacgtgag ggaagaaaaa tgaatatcgt ttcccgtggc ggttcactgc
     2821 tcttcgcatg gatgatgatg acaggcaatg aaaacccatt cttcgagtat tatgacgagg
     2881 tgcttgaaat actcagagag tatgacgtta ctatctcact tggcgacgca ctccgcccgg
     2941 gatgtcttgc agacgcctcc gacgccgctc agatctccga acttatcgag cttggcaacc
     3001 tcacaaagag agcgtgggaa aaggacgttc aggtaatggt agagggtccg ggtcatatgg
     3061 caatgaacga gatcgccgca aatatgataa tggaaaagaa gatatgccat ggtgcacctt
     3121 tctatgtact tggacctctg gtaacagata tcgctcctgg ctatgaccat atcacatcag
     3181 ctatcggcgg agcaatagcc gcagcaagcg gtgcagactt cctctgctat gttacccctg
     3241 ccgagcatct cagacttcct gacgttgacg acgttaagga gggcattatc gccagcaaga
     3301 tagcagccca tgctgcagat atcgcaaagg gcgtaaaggg tgcaagagat atagacgata
     3361 aaatggcggc ggcacgtcac aaaatggatt gggacgaaat gttcgagata gcacttgacg
     3421 gtgaaaaggc aagaagattc tttgagcaga ccccacctgc cgacagacat acctgctcaa
     3481 tgtgcggcaa gatgtgtgcc gttagaacaa caaacatgat actcgagggc aaagaggtga
     3541 aattctgctc agagaagtag aaaactcgat gtaggggcga acagcattcg cccgcatgat
     3601 ataaaaattg aatgtcagct cggcagttgt gcgaaaaatc ggacaattac atgagagcag
     3661 atataaaaag aatgtaatgt gcaagaggag cgtcttgcga actttttcat aaaaagtatt
     3721 cagcgaggga acccgtgttt cggggtgaga gggtgcaatg gagcaccgac cgaaaataat
     3781 ttacgtcaga tcgtgagcgg atagcatagc cgcggtctgt gcgccgctgg ataacttgct
     3841 ctttttcgtt cggcggtgcg atacgatatg gaggaataaa aatgaaaaag acaaacattc
     3901 acaaattggt attcgcagca gtattggtag cccttgcagt ggtaggctcg ctcatctcgt
     3961 tccctatcgg cgcttcaaag tgcgcacctg ttcagcacct tgtaaacata atcggtgcag
     4021 ttttccttgg acctgcgtgg gcagtgggcg ttggcttcac agccgcactt ctcagaaatc
     4081 ttctgggact tggctctctc cttgcgttcc caggctcaat ggttggcgca ttcgttgcag
     4141 gtatgcttta taagtacata aagaagctcc ctgccgctta tgtcggcgag cttttcggca
     4201 cgtcagtcct cggtggactt ctggcatacc ctgttgcaag atttctcgtt ggcgcaccag
     4261 ctgcagcaat aacagtatat atcctgcctt tctttgtaag ctgtgcaggc ggtacagttc
     4321 ttgctatcgt tatcgttaca gctcttaaaa aggcaaaagt atttgataat ttccttggct
     4381 tctcaaagga ggtaagagca taatgggcac tataattgaa agctgtgcga aagcagcaga
     4441 caaggtaaga gatatatgcc ctttggtgca ttgtatcaca aattatgtta ctgtaaatga
     4501 cgttgcaaac tgcattctcg ccattggcgc ttcacctatc atggcagacg atatcgcaga
     4561 agcagcagat ataacttcta tctcaaaggc tctcgttata aacatgggta ctctcaatgc
     4621 aagaacggtc gagtcaatgg tagctgctgg aaagaaagcc aacgagcttg gcgttcctgt
     4681 ggtttttgac ccggttggag caggcgcatc aaatttcaga aatgaaactg caaagcgtat
     4741 acttgaaaat gtgaaaataa gcatactcag aggaaatctt tctgaaatgt catatcttgc
     4801 aggactagaa gtttccacaa agggtgttga cacctcggaa gctgacgaga aaaacgaccc
     4861 tgtttccgtt gcgaaaaaaa cagccgctaa gtataactgc gttgcagcta tcacaggtgc
     4921 ggtggataca ataacagacg gaaaaagagt cgcaaggata tcaaacggtc acccatatct
     4981 ttcaaaggta acaggcacag gctgtatgac aacaggactt gtaggctcat ttgcaggtgc
     5041 ttgcgacgat atgtataccg ccgctgtaac aggcattgca agcatgggca tagcaggcga
     5101 gttcgcatat gaaaatgctg gagagatagg ctcaggaagc ttccatattt ctatcattga
     5161 cgcaatcagc aaaatgaata gtcaggtatt tgcggctaag gctaagatag aagaagttta
     5221 gtattgcaat atttcagatc tagtggtatc atatcaatgt gatgccacta aattttatgt
     5281 ggtgatgttg cttgcagggg cgaacagtgt tcgtccgttt gcattgcata ttatactttt
     5341 tcatacaaag gagaatgaaa aatgaccgta agatttgctt gtgaaaagga tataccgcaa
     5401 atgaacagcc tgctctatca ggtagagaga gttcatcagc agggcagacc tgaccttttt
     5461 aaagagggtg cgaaaaagta tactgataac gagcttaaag atatgctcaa ggataaaact
     5521 aagcctatat ttgccgcagt tgatgaaaat gatgtgatga agggctacgc tttttgtgtg
     5581 tttcaggagc ataagggcga caatgttctc acggatataa agactttgta tatcgacgat
     5641 ctgtgcgttg atgaaaattg cagaggtcag catatcggct cggtgcttta cgaggcggtg
     5701 aagaaattcg ctaaggagca gggctgttat aatgttactc tcaacgtgtg ggagtgtaat
     5761 ccatcggcaa gaaaatttta cgaaaaagca gggctgaagc catacaagac aggtatggaa
     5821 gttattttat gataaaagat aagagggtaa aaaaatggac aaatcgaaaa ttgactacac
     5881 gctttatctc tgcactgacc gtggacttat gtcctgcgaa actatcgagc agtcggtaga
     5941 ggagggcgta aaaggcggct gtacagttat ccagctaaga gaaaaggact gcacttcaag
     6001 agagttctat gagcttgcag ttagagtaaa aaagataacg gacaaataca atgtgccgct
     6061 tatcatcaac gacagactgg atatcgcaca ggctgttgac tgtgcaggcg ttcatctggg
     6121 acagagcgat atgccatgtg cagttgcaag aaaaatcctc ggtgaggaca agataatagg
     6181 tatttctgcg gcaactcttg aagaagctaa aaaagcacag gtagacggtg cagattacct
     6241 tggcgttggt gcaatgtatg ccaccaacac aaagacagac gcaagagctg tcacaaagga
     6301 acaacttgta gaaataagag ccgctgtgga tattcctatc gtaataatag gcggagttaa
     6361 tcaaaaaact gtgccgaact ttaagggtat gggtattgac ggcgctgcgg tagtttctgc
     6421 ggtggtttct cagcctgata ttgaaaaggc ggcaaaggat cttcgtgagc tttgcgagga
     6481 ttgcttcgga agataagatg ttcaacgggc ggttattaag atcgtccgtt ttttgttttg
     6541 aaaaatgtat gattttgttt ttcgatttta cacaaattat acattgtgct attgacgatt
     6601 aagttaaaat cggttataat aaatgaaaaa gctttgtttt tttggattaa aacgctaatg
     6661 cgttgaaata gtaatgtatg ttaggagagt aaaaatgaaa aaaactaaga tcgtatgcac
     6721 tatcggacct tccacagatg acgaaaacat tatgcgtgag cttatgaaaa acggcatgga
     6781 cgttgcgaga ttcaatttct cacactctga ccacagtgtt cataaggctc gttttgaaac
     6841 tgtatgcaag ctaagggaag aacttggcgt taatattgca actcttcttg atacaaaagg
     6901 acctgaggta agacttaaaa actttaagga tcacaagcct gttactatca aggacggcga
     6961 tacattcaca cttaccacaa gagaagtgga gggtgatgaa actatctgct ctatcacatt
     7021 cccacagctt ccaaaggacg tttctgtagg cactagaata cttattaatg acggaaatat
     7081 cgagctgaaa gctaccagag ttgacaacac cgatatcgtc tgcgaagtta tccacggcgg
     7141 agttgtttcc gaccacaagg gtatcaacgt tcctgacgta aacctttcta tgccttatat
     7201 ctctgacgct gatatggctg accttgaatt tggcgcaaaa atgggatttg actatatcgc
     7261 agcttcattc gtaagaacag gcgctgacgt tatttatctt agaaaattta cccagagcct
     7321 tggctggttc aatcctagaa ttatcgctaa gatagaaaac gctcagggtg ttgccaacat
     7381 cgacgagatc cttgacgctg ctgacggaat aatggtagca agaggagata tgggcgttga
     7441 gatacctttc gagcagatac ctgctataca gaaagagctt atcagaaaag cctacaacgc
     7501 aggcaagaac gttatcacag caactcagat gctggagtct atgataacaa acgcacgtcc
     7561 tacaagagcc gagataaccg acgttgcaaa cgctatatat gacggctcgt ctgctataat
     7621 gctttcaggg gaaactgccg caggtaaata tcctgttgag gctgtcaaga ctatgagcct
     7681 tatcgcagaa acgaccgaaa aggatatcga ctatatctca cgtttcaaga aaagagcaga
     7741 tgagagaaat tcatctatca ctgacgctat ctcacacgct actgttacaa ctgcccatga
     7801 ccttaatgct gtagcgatcc tgacagttac aaagggcgga acaacagcaa gaacgctttc
     7861 aaaattccgt ccgaactgtc ctataatcgc acttacaact gacgatacaa catatcatca
     7921 gctcagcctt tcatggggta tcagagcagg cgttatcgaa gagaaaacaa acactgacga
     7981 actcatcaga cacgctctgg agcgttctgt ggagcttggc tatctgaaga agggcgacct
     8041 tgtcgttatt acagcaggag taccgcttgg aatgagcgga acgacaaatc tgctcaaagt
     8101 cgagagagcg tagtttttaa gtgaggagtg aggagtgagg aatggcagcg ccataccgag
     8161 caaatcacca acccaaagta aaaacatcca cgagtgaagc gagcaaaatg tctgcggaga
     8221 gagccttaat aggaacaagc ttactaagcg gtgcagaaaa gcaatagaag aattgcaaaa
     8281 aaatcaatta caaagcggtg tggagtggaa tactctgcac cgcttttgtt gcaaaaaatg
     8341 tttgagcttt ttgtaggcga tcactttttt attcaaataa ttttccgtga attgggtaac
     8401 cgattctaac atatgaaaga agtatggcgt aagagtaata tttctgaatg tgacttgact
     8461 ttgattttga agtatgttat tattttaaca tacgagcggt agtattatta ataggtatgc
     8521 aatactgaat attgaggtaa tatgtgctgc ccgaaatctt atgtcaggag agtataaaat
     8581 ggaaagacag ttttatgacg aatgggaagg ctttaagccc ggcagatggt caaacacttc
     8641 tatcaatctt cgtgatttta tccagaagaa cttcacacca tatgacggtg acgacagctt
     8701 ccttacaggc cctacagaag caactactaa gctctgggaa caggtaatgg agctttcaaa
     8761 gaaggagaga gaagccggcg gtgttctcga tatggacact aagatcgttt ctactatcac
     8821 ctcacacggc cctggttacc ttaacaagga tcttgaaaag atcgttggtt tccagactga
     8881 caagcctttc aagcgttctc ttcagccttt cggcggtatc agaatggcta tgaatgcttg
     8941 cgagcagaac ggctacacag ttgatcctga agttgtaaag atctttactg aatatagaaa
     9001 aactcacaat cagggcgttt ttgacgctta cacacctgag atgaagcttg ccagacacgc
     9061 tgctatcatc acaggtcttc cagacgctta cggcagagga agaatcatag gcgactacag
     9121 aagagttgct ctttatggta tagactatct cgttgaggac aagaaggatc agcttgctac
     9181 ttcactggta agaatgactt ctaagaacat cagactcaga gaagagcttt ctgagcagat
     9241 cagagccctt ggcgaactca agaagcttgg cgagatctac ggctacgata tctctcgtcc
     9301 tgctaagaac gctaaggaag ctatccagtg gctgtacttc ggctaccttg ctgctgttaa
     9361 ggagcagaac ggtgctgcta tgtcacttgg cagaacttct acatttattg atatatacat
     9421 caagagagat atggacagag gtatcctcac agagcaggag gctcaggagc ttgttgacca
     9481 cttcatcatg aagctcagac ttgttaagtt cgctagaaca cctgagtata actcactgtt
     9541 ctcaggcgac ccaacttggg taacagagtc tatcggcggt gtttctatcg acggcgttcc
     9601 aatggtaaca aagacttcat tcagatatct ccacacactt gagaaccttg gtcctgcacc
     9661 agagccaaac atgacagttc tgtggagcac aaagcttcct ttaaacttca agaagttctg
     9721 tgctaagact tctatcaaga cttctgctat ccagtacgag aacgacgacc ttatgagagt
     9781 tacacacggc gatgactacg ctatcgcttg ctgtgtatct tcaatgagga tcggtaagga
     9841 aatgcagttc ttcggtgcaa gagctaacct tgctaagtgc ttgctttatg ctatcaacgg
     9901 cggtgttgac gaaagactta agatacaggt tggtcctaag tatcgtccag ttacaggcga
     9961 ttacctcgat tatgatgatg taatggctaa gtatgacgat atgatggagt ggctggctgg
    10021 tctgtatgta aatacactga acgttatcca ctatatgcac gacaagtatt cttatgagag
    10081 agttcagatg gctcttcatg acagagatgt taagagatac ttcgctactg gtatcgctgg
    10141 tctgtcagtt gttgctgact cactttctgc tatcaagtac gctaaggtaa agtgcatcag
    10201 agatgaggac ggaatcgtta cagattacga agttgagggc gatttcccta agtatggcaa
    10261 caacgacgag agagttgaca agatcgcagt tgacctcgtt agaacattta tggacaagat
    10321 cagaaagcac cacacataca gagatggtgt tcctacaatg tctatcctta ctatcacatc
    10381 taacgttgtt tatggtaaga agactggttc tacacctgac ggaagaaaga tcggtgtgcc
    10441 tcttgctcct ggtgctaacc caatgcacgg cagagatact cacggtgcat ctgcatcact
    10501 ttcttcagtt gctaagctgc cattcagaca cgctcaggac ggtatctcaa acacattctc
    10561 tatcattcct gacgctcttg gcaaggacga caaggtattc atgggcgacc ttgatatcga
    10621 aagcatagct aaggagctta acgaagatgg ggtttaatgt taaaaaggac gaggacgagg
    10681 ctcaggtaaa cgagcttgtt gacgtcattg acagacttat gatgggcggt cagggtcatc
    10741 ttacgataga cattgacgaa actgaagaag gtctgaacgt taaaacttac agcacttccg
    10801 attgtggcgg tgacggcaag acggcttgct gtcagcctac agaagaggac gctgttgaca
    10861 gagatgaaga ttaactccct attttagaaa acggcggagg ttcgttttcc acttgttttc
    10921 cataaatact aagaaaggaa tgtaatacaa tggcaaactt tgaaccaaca gaggcacaga
    10981 tagacaacct tatcggactt cttgacggat atgctgaaaa aggcggtcat caccttaatg
    11041 taaatgtact taacagagaa actcttctgg acgctcaggc tcaccctgag aagtatccac
    11101 agctcactat cagagtttca ggctacgctg taaattttgt aaaacttact aaggagcagc
    11161 aggacgacgt tatttcaaga acgttccaca agagccttta atttgagctt tgccgcatag
    11221 aatgagtttc tttgcggata atatgcacac gggcggtcgg cgtcgtctta catggaacat
    11281 cttgttttat gtggatgaga gctgccgctc gtttgttact ttttgtggat aggtgtgcgg
    11341 tgatataaat ttgtgagcga gcagaaacgg gacgtcgagg gcgccgtccc ctacagaatg
    11401 gtttgtgcag gctgaacggg cgtgcgttta tgtgaaataa aaaaggaggg atatcccatg
    11461 gagggattta tacattctac ggaaagcttt ggtacggtgg acggaccggg gataaggttt
    11521 gttattttct ttcagggctg tcctatgcgg tgtctttact gccacaatcc tgatacttgg
    11581 aagataggca ctggtacaaa gaggacggtt gaaagtctgc tggcggaata tgactcggta
    11641 aaagagttca tgaaaaacgg cggaattacc tgcacgggcg gtgagcctct ggtacaaata
    11701 gactttgtta cggagctttt tgaaaaggct aaggaaaagg ggatacacac ttgtcttgac
    11761 agctcgggca tcacttttac gcctgacagc acggaaaagt ttgaaaggct ttgcaaatgc
    11821 actgaccttg ttatgctgga tatcaagcat attgaccgtg aggaacacaa gaagcttacg
    11881 gggcattaca atgacaacat tcttgcgttt gcaaagtttt tgtcggagta tggtgtgcct
    11941 atatggatac gtcatgttgt tgtgccgggt atcacggaca aggaagaata tcttttcagg
    12001 ctgggtgagt ttatctcaca gctcaagact ttgaaagcgc ttgacgttct gccttaccac
    12061 actatgggca aggtgaagta tgagcagcta ggtatagatt atcctcttgg tgacacgccg
    12121 cctcttgaca aggaggacgc tgttaaggcg agagatgtta tcatgagagg gcttaaagcg
    12181 gcgttgaaaa agagaaaata gtattttaga cgagtggact tcggtctgct cgtttttttg
    12241 tgtaaaagta tatatttttc tcgacaagtt tttgaaaata ttctgcatat ttggataatt
    12301 gacggcaggc ttaaaatatg gtaaaataaa taagtaagga atacagcaat agaatattgt
    12361 taggacaggt ttatattgga aacgcacatt ctctgaatga taacgaacaa cacagcgtct
    12421 gcgaaagggc tgtaggtttg atatcataag gaggattttt ttatgccaaa gaatttgttt
    12481 caggagatag tttttacggt gctgatggtg tttgtgatgg tatacgccat gatatgctac
    12541 aacattgcac tcaacatggg cggaatgtca aatgccgtat ttctcaaggc ttttcacgag
    12601 cttgtgataa tggctccgat agcttttgtt cttgactttt ttgctgtggg aaagatagca
    12661 aagaaaaagg ctttcagcat tgttgatgtg agaaaggata atccttttca tcttgtgctt
    12721 gccatatctg ttatctctgt tatttttatg tgcccactca tgagccttgc ggctacgctg
    12781 ctttttaagg acgcaggcag ggaagttatt gcggtatggt tagaaacaac ggttatgaat
    12841 tttcctatgg ctctttgctg gcagcttttc tttgcaggcc ctatagtgag gtttgttttc
    12901 ggacttattt tcagagagcg tgaacagaaa agcgaggctg tatctgcagc tgcggaataa
    12961 ggtttttacg agtggacttc agtctgctcg ttttttattt tacactgaaa aataaaaact
    13021 aaaaaaagtg ttaaaagcct ttacaaaggc aggcggttgt gttataatag taatcgtaaa
    13081 aatttgcgtg aaaaaggagg agcttatagt gcagaaggcg tatctgattt tggagaacgg
    13141 tactattttc gagggtaaaa gtttcggcgc agctggcgaa gctattggcg aaattgtttt
    13201 tactacggct atgacaggct atctcgaaac acttactgac cctagttact acggacagat
    13261 agttgttcag acatttccgt taattggtaa ctatggtgtt attcctgagg attttgaaag
    13321 tgaatgtcct catgttaaag cttatattgt tagagattgg tgtcaagagc ctagcaactt
    13381 ccgttgtgag ggtgatcttg acactttttt aaagcagcat aacatcgttg gtctttacgg
    13441 tatcgacact cgtcagctca caaaaatagt tcgtgagtcg ggtgttatga acggaaagat
    13501 cgttcctgag ggttcaagct tcggcttgac agatctgaag aactacacga tagttgaggc
    13561 tgtaaagaac acgacttgct cggaggaaaa gacattcgag cctgagggag aggtcaagag
    13621 aaaggtagtg ctttacgatt ttggtgcaaa gcacaacatt ggaagagagc ttgttaagag
    13681 gggctgtgag gtaactgtcg ttcctgcata cacaaaggca gagaggataa aggagcttgc
    13741 acctgacggc ataatgcttt caaatggtcc tggagatcct gcggagaatg tggagataat
    13801 cgaggagctt aaaaagcttt ctgagatgaa gatacctact tttggaattt gtttgggtca
    13861 tcagcttttg gcgcttgcac atggtgcgat gacacacaag ctgaagtatg gtcacagagg
    13921 tgcgaaccag cctgctgaga acactgaaac aggcagagtt tacataacat cacagaacca
    13981 tggatatgca gtagaaaacg attcgctccc tgagggtgaa gcaaaggtgc tttatgtaaa
    14041 tgccaatgac ggcacttgtg agggtatcag atatctcaac gagcctgcat tttctgtaca
    14101 gttccaccca gaggcttgtg gtggtccgca tgatactgac ttcttgtttg atgagtttat
    14161 tgagctcatt gacactaaca agaagtaagc tctgattttt tgaagtatag aaattattga
    14221 tctcagtttc tgcaacagta ggggcgaaca gtgttcgccc gtggctgacg gaatgtgttt
    14281 gatatgacta ttgtagtgtt cattattcga gcggctttta tatggggcgg tcgtgatagt
    14341 gaacgggcga acgctgttcg cccctacatt atgttttact gaggtcgtta agctttaaca
    14401 cagagggctg ctgggtgcgg ttttcgagag tgtgagaagg gataactcct cactcctcac
    14461 tcctcacttt cagtgtttcc ctaaactttt cagaaaggat tgaatttaag tgcctttaaa
    14521 taaagatata aagcgagttc tcgttatcgg ctcgggtcct atcgttatcg gtcaggccgc
    14581 tgagtttgac tatgcaggta cacaggcttg ccgtgcgctc aagcaggagg gtctggaggt
    14641 tattcttata aactctaacc ctgctactat catgacggac aatgctatgg ctgacaagat
    14701 atacattgag ccgcttactc ttgaaactgt taagagagtt atcaaaaaag aacgccctga
    14761 cagcctgctt tctacccttg gcggtcagac gggtcttacg ctttctatgc agcttgctaa
    14821 ggagggattc cttgacaagt ataatgttaa gcttcttggt gctaaccctg aaactatcga
    14881 taaggctgag gacagacaga tgttcaagga cactatggag tctatcggtc agccatgtat
    14941 cccttcaaag gtcgttaata ctgttgagga cgctgtagac ttcgctaatc agcctggtat
    15001 cggttatcct cttatcatca gacctgcttt tacacttggc ggtacaggcg gcggtatagt
    15061 taatgatgaa gaagaactga aagagatcac aagaaatggt ctttatcttt cacctatcac
    15121 tcaggtgctt gttgagaaat gtatcgcagg ctggaaagag atagagttcg aggtaatgag
    15181 agacgctaag ggcaacgtta tcacggtttg ctcaatggag aactttgacc ctgttggtgt
    15241 tcacacaggc gactctatcg ttatcgctcc tgctgttacg ctggctgata aggaatatca
    15301 gatgctccgt tctgcggctt tgaagataat cgatactctt aaagtagagg gtggctgtaa
    15361 ctgtcagttc gctcttaacc ctgatagctt cgagtatgct gttatcgagg taaaccctag
    15421 agtttcacgt tcttccgcac ttgcttctaa ggcgaccggt tatcctatcg ctaaggtcgc
    15481 agctcagata gctataggat atactcttga cgagataaag aatgctgtaa caggcaagac
    15541 ttatgcttgc tttgagcctg cccttgacta tgttgttgtt aagctcccta agtggccttt
    15601 cgacaagttc gtttatgcta agcgtgagct tggtacacag atgaaggcta ctggtgaagt
    15661 tatggcaatc ggctcaactt ttgagcaggc tataatgaag gctgtaagag gagctgagat
    15721 aggtcatgac tgccttatct cacctaagat gcttgacctt gatgacaaga ctatccatga
    15781 cagactttct gactgcacag acgaaagact tttcgttgta tacgaggctc tcagacgtgg
    15841 cgtttctgtt gatgagatac acagcatctc taagatagac gagtggtttc tctacaagct
    15901 ctgcaagctt atcgacatgg aaaagacact caaaaatgac ttcaacgagg aaacttatct
    15961 tgaagctaag aagataggct atactgataa ggtcattgag aagataaccg gcaagaagat
    16021 agaaaagcct gttcatgctg tatttaaaat ggttgatacc tgtgcggctg agtttgcggc
    16081 tatgacacct tacttctact caacatatga caacgaggac gaggcaagcg agttcattgc
    16141 aaacagaggt catgacagaa agactgttat agtattcggt tcaggtccta tcagaatagg
    16201 tcagggtatc gagttcgact atgcgtctgt tcactgcgta tgggctttga aagaaaaggg
    16261 atatgacgtt gttatcgtaa acaacaaccc tgagacagtt tcaactgact ttgatactgc
    16321 tgacagactt tatttcgagc ctcttaccga cgaggacgtt atgaacatca tcagagttga
    16381 gaagcctgtc ggcgttgttg tggcattcgg cggacagact gctatcaagc ttacaaagca
    16441 tatggctgaa catggtgtaa acattcttgg tactcctcct gacgctatcg acgctgctga
    16501 ggacagagag agatttgacg agctgcttga acagctgaaa ataaagagac ctcagggctt
    16561 cactgttatg acttgtgacg aggctcttga agttgcaaat aagatacatt atcctgttct
    16621 tatgagacct tcttacgttc tcggcggaca gaacatgata atcgcattca acgatgacga
    16681 tatcaaggaa tacatggcta tcattctcga ccagggaata gagaaccctg tacttataga
    16741 caagtatctt atgggcactg agcttgagat agacgctatc tgtgacggcg aggatattct
    16801 tatccctggt atcatggagc atatcgagag aacaggtatc cactcaggcg actctattgc
    16861 ggtttatcct gcatggaatg tttctgacag cttgataaac agaattatcg aatgctcaaa
    16921 gaagcttgct atcgcactta acacaaaggg tcttgtaaat attcagtata ttgcatacca
    16981 tgacgagata tatgttatcg aggtaaaccc acgttcttca agaactatcc cttatatctc
    17041 taaggtaacg ggcgttccta tggtagacct tgcaactaag tgtatgctgg gcgaaaagct
    17101 caaggacatg ggctacggca ctggccttta cagaaattca ccatatgttg ccgttaaagt
    17161 tcctgtattc tcattcgaga agcttatcgg cgttgacaac caccttggac ctgagatgaa
    17221 gtcaacaggt gaggtgcttg cagtttctaa ttctcttgaa gagtcactgt ataagggtct
    17281 tactgctgcg ggctacaagc ttggcaagaa gggcggagta ttcatcactg tcagagattc
    17341 tgacaagggc gagataccac agacagctaa gatgttcgct gaccttggat ttaagatata
    17401 cgctacaaac ggcactgcta aggtgcttca cgagcacggc attgacgctg aggtagtggc
    17461 aaagatacac gagaacgagg acaacaacac tctcacactt atcgagagcg gaaagatagc
    17521 ttatgttatc tcaacttctt caaagggaag aatacctaca agagattctg ttaagataag
    17581 aagaaagact gttgagtgga acattccttg tctgacttct atcgacactg caaacgctat
    17641 tgcggcatct atcagaagta aatacactga gtcaactact gagatagttg atatcaacaa
    17701 catgagaact gaaaagcaga catttgagtt cactaagatg cagggctgcg gcaatgacta
    17761 catctacttc aactgctttg accagagaat agacaatcct gagggcctgg cactcaatct
    17821 gtctgacaga cacttcggta tcggcggtga cggtgttatc cttatctgcc gttcaaaggt
    17881 cgcagacgct aagatgagaa tgttcaatct tgacggttct gaaggcaaga tgtgcggaaa
    17941 cggtatcaga tgcgttgcta agttcatgag agataacggc attgttgaca aggacgaaat
    18001 gactatcgaa acactttcgg gtatcatgac agtttcactt atccgtcact acggtgaggt
    18061 aagcggtgct actgtaaaca tgggcaaggc tattcttgct cctcaccttg ttcctgttga
    18121 acttgagcct gacgagaacg gcagggtagt tgacagaaag gtgaacattg caggaaatga
    18181 ctacaacatc acctgcgttt caatgggcaa cccacacgct gttgtattca tgaacaatgt
    18241 tgacagcctt gacattgaca aggtaggtcc tgagttcgag catgacaaga tattccctga
    18301 gagagtgaac gctgagttta tcaaggtgat cgatgaccac acactcaaga tgagagtatg
    18361 ggagagaggc tccggcgaaa cttgggcttg cggcaccggt gcttgtgcag cagcagttgc
    18421 ggctgttctt aacggattct gcaaaaagga cgaggagata tctgttatac ttaagggagg
    18481 cactcttaag ataagataca cagacgaggc tgtatatctt acaggcgacg ctgtaacagt
    18541 attttcaggt cacatcgtaa tgtaaatttc gcagcggaca ctgcgttaaa aaagcggcag
    18601 ccgcagagcg ttttgaatgt gctttgcggc tgtgtgcgtt ttataagttt gacccgtgaa
    18661 acttcgggtc gcaaaaatga aaaggagttg gaattatgcc aagtataaac gaaaattttc
    18721 tcaagctgga aaagaattat ctttttataa acattgccaa gaaggtaaag gccttcactg
    18781 aggcacaccc tgaggctgac attatcagaa tgggtatcgg cgacgttact cagcctatcg
    18841 caaagtgcgt tgttgaggca atgaaaaagg gcgctgacga aatgggcgtc aaggaaacat
    18901 tcaagggcta tgaggacagc ggtgcaggat atgacttcct gaaagaggct gttgcaggct
    18961 actacaagag cttcggtgtt gacattcctg ctgacgatat caggataaac gacggtgcaa
    19021 agtctgactg cggaaacatt gttgacattt tcggtgacga caatgtagtg cttatcacag
    19081 accctgcata tcctgtttat gttgacacga accttatgaa cggcagaaag gtaatttatg
    19141 ctgattcaaa cgaggagaac aactttgcgg caatgcctga cgagaacgta aagtgcgaca
    19201 ttatttatct ttgctcacct aacaatccaa cgggttctgt ttacactaag gagcagctta
    19261 aagtttggat agactatgca aagaagaaca acgctatcat catttatgat tctgcatacg
    19321 aggcattcat tacagaaaag gacgtaccaa gaagtatttt tgctgttgag ggtgcaaagg
    19381 aatgtgctat cgagatgtgc tcactttcaa agacagcagg cttcacaggt atgagatgcg
    19441 gatatacagt tatcccacac gagcttgttg ttaaggcatc tgacggcagc gaagtttcta
    19501 tcgctcagct ttggggcaga cgtgaaggct caaagttcaa cggtgtatca tatcctgttc
    19561 agtgtgctgc tgcggctgta ttcactgagg agggtcagaa gcagacaaga gcaaacattg
    19621 aatactatca gaacaacgca aaggtaatgg cttccacact tgacgagctt ggtattaagt
    19681 acacaggcgg caagaactcg ccatacatct ggctgaaatg ccctaacaac atgggttctt
    19741 gggagttctt tgattatctt cttgagaatg caaatgttgt tggcacacct ggcgcaggtt
    19801 ttggcaagaa tggcgaaggc tggttcagac ttactgcttt tggtgataag gacagaactg
    19861 ttgaggctat ggagagaata aagaagctgc tttctaagta gtgaggagtt aggaattatt
    19921 cttgctttta ctctgatatt ctcggatagg ttttatatga ttttaaaagg gcggttttga
    19981 ccgctctttt ttttgttcgc aaattctacc gtcgcaaaat cgcttcgctc tttgcgtggt
    20041 ggggttgtaa aatgagatag taaaagcggt gcagattttt tactccgaca ccgctttgtt
    20101 atttgcttta gtttgtgttt cttctacttg gtagtggctc tttgctaggt ttggctatgc
    20161 caatcctcac tcctcactta gcctacacct ttattcttcg atactctccc ggagtcatat
    20221 tttcataccg tttgaatacc acggagaaat aagatccgtc ctgaaagccc gtttcatctg
    20281 atatctcgcc tatggtcttg ttggaataca caagcagatc ctttgcgtgc tgtaccctta
    20341 cttgcgcaag atactccata ggtctgagct gaaaattttt cttaaaaagt ctgcataagt
    20401 gctgctcgga tactcctgcg atttttgcaa gctcgttaag ctttatttgc tccggataat
    20461 gctcttcaat atactgcaat acgtctgcca gggcaacaga ttgtgcggta taaaatgacg
    20521 agagcctgtt atcagctatt ttacgatatt ctataagaaa gtcgtaaagc tgtgctgaag
    20581 cgtaatgatt gccataaagc ttatcacttt tcagagtata atagatgcgt gttatgatac
    20641 ggcgtaatct gtccatatct accccttgaa tggcggtgaa cttattaagc ttccactgct
    20701 ccaagagggg aatgacctgt gagccggaaa aggctatcca atccagatac cacgcatcgc
    20761 ttagcgcatg atactcatga ggacagaatg gggggatata gaaaacagta tcgggcggta
    20821 tttttgtggt ttctccgttt attatgacct cgccctcccc tgagcgtgac aaaaatattt
    20881 gtgggtactc gtagccatct gcacgtttta ttggaaactg ccagctttca agtcccagac
    20941 ctaccacata aaagggcagg tttttttcgt cgcctatgac gggatatatc tgtttgtaca
    21001 ttattctgca cccccaattt acatatcttt ataataccac tgggtttggg gtttgtcaag
    21061 ataaaactat tcttttgccg agcttttaaa gaaaagcgaa aagataaagg cgaatgtcat
    21121 ggctgcagtt atgcctgcgg cggaggcggt aagtccccct gtgaaaatgc ctaggaagcc
    21181 tattttatct atctgttcac ggacaccgtt atagagaaga tagccgaagc ccgtgagagg
    21241 gacagttgcg ccacagcctg agaggtctat aagtggctta taaagtccca gcgcacctag
    21301 aagcacgccg cctgtgacgt atgccaccag tattcgtgcg ggggtcagtt ttgtgaagtc
    21361 cataagcacc tgtcctatgg cacaaaaaag acctcctata agaaaagccc atagatagtc
    21421 cattagtttg ctcctttcat atctttttcc cctgacagcc acacgagatg tgagatagag
    21481 gggatagatt ccccttgctg atttactgtt ggtgacatta gcgcacccgt ggcagcaaag
    21541 aggatatttt ttatttcacc tgcacggagc ttcgggagaa aatagccgca cagaacgctt
    21601 cctgcacagc cacagccgct tccccctgcg tggatatcct gctcgtcaaa gtcatagagc
    21661 atcataccgc aatctttatg attgtcacgg atatttatat tttcacgctc gaaaagctca
    21721 cagagaatac ggcttccaac tttgccaagg tcgcctgtga cgatataatc gaagtcggag
    21781 ggggtcatgc ctgtgtcggt gaaaaatgtg cttatggtgg aaaaggctgc aggtgccatg
    21841 gctgcaccca tgttgttggc gtcgctcacg cccaagtcaa ctatttttcc gatagtacag
    21901 cccctgatgt aggggggctt gtccgagggg gcaaccacca atgagcctga ggctgtggct
    21961 gtccactgag atgtgggagt acgctgtcca ccgtagttga ggggaaagcg gtactgtctt
    22021 tcagcggtgc agaagtggga agatgtgacc gccattgctt tttttgccag gtcgttgtca
    22081 acgaaaagag aggcgaggag aagtccctcc gccatggtgg agcaggctcc gtaaatgccg
    22141 agaaagggca tttcaaaggc tcttactcca taggtagtgc cgacacactg atttagcagg
    22201 t
//
