LOCUS       c00012_NZ_JHYF..       14646 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHYF01000015.1 Alkaliphilus transvaalensis ATCC 700919
            T335DRAFT_scaffold00012.12_C, whole genome shotgun sequence.
ACCESSION   NZ_JHYF01000015
VERSION     NZ_JHYF01000015
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:31:14
            Original ID  :: NZ_JHYF01000015.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 145296
            Orig. end    :: 159942
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14646
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[155296:159941]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14645
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
     cand_cluster    1..14646
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /kind="single"
                     /product="Glycine_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14646
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_reductase"
                     /region_number="1"
                     /rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /tool="gutsmash"
     CDS             complement(106..1044)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_146"
                     /sec_met_domain="Acetyltransf_10 (E-value: 4.7e-10,
                     bitscore: 32.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKITSETMHDFAEKIEYGKKHFIPMLPFVRIPYHNFDKYKTFSE
                     KGIYLIDYVDDEYCLYHLYHLTPGDDTLRATLILPSNWNKRFEIIEKSIPNLKEWFLRE
                     DDSKKFIIQSLEYGEIEYFPTLSHYLIPTIIKNGFNPKYRMYMKLEDGETETEPTPIVN
                     LLNSSLRVVNFSEEMLEDVIDFYYRNESTKNYQYFTNCTFEEFIEMFKQEFTTTYSKFI
                     LDAQGKIVAGILPTRENDKIWIDNFTVHPAYSNSNVGEYLLNQALKKILKDQPNETICI
                     YLNRDCYEAVEACEKNGFTSFEFWTDMILEK"
     CDS             complement(1218..2321)
                     /locus_tag="ctg12_147"
                     /transl_table=11
                     /translation="MDKTHLENQLKDFFKKAIQKDKNIKNAFMLIHSDKYNLHLNMAEG
                     TTEGVASVPNQPFHIASIGKLFTSVLTSILVEKNEIFFDDSISLYLDEELLKGLHIYKG
                     IDYTDQIKIKHLMNHTSGLNDYFEDTPKNGKSMLQMIEDDPYRSWKPREIILWSKSNLK
                     THFPPGRGFHYSDTGYHLLGLILEKITKMPLAEAMDYYIFSPLEMHHSYLASHSEPKKK
                     SAISVADVYMKGVNAKDFSILKDDYAGGGIVAPAEDLLKFMKALVHHKLIKEETFEKMK
                     DWAGFFNLFFIGIDYGYGLMNFKTIPLVMPSKYNVWGNAGSIGSFMFYHPLTDSYFIGS
                     LNNFRYHRKGIRLMFKAIDILLKKAPS"
     CDS             complement(2365..2934)
                     /locus_tag="ctg12_148"
                     /transl_table=11
                     /translation="MAPKKKFSKEAIINTGFEIAKIEGINSITIRKVAEKLGSSIAPIY
                     VNFNNIDELIEEVIKKVYQISHQIYLEENTGSPFRDIGVASLRFAKEYSLLFKDMMMNS
                     NQYMKNYDEDMGEFLIEEMRKDPELADFSDMELQTILLKMRIFQTGLSVMVANNLLPQN
                     ITENYIKRLLDDTARDIVYSTASKIK"
     CDS             3148..3846
                     /locus_tag="ctg12_149"
                     /transl_table=11
                     /translation="MFGSSISQLTVELTIGFFALFVVTKITRKSQINQITPFDFISAIV
                     LGELLGNAIYDEKVRIWTIMYALALWGILMVFIEKITQKLRRTRKLLEGEPAIIIRNGQ
                     IDYNVIKKEKLDINELLSLLRQKDAFSIREIEFAILEQSGNISVLKKSKYESATIEDLN
                     LQEHPVYLPITLILDGEIIKNNLYAIGHDENWLFNQIRKAGEKNIENIFYADWKQDEGI
                     HVVPRNNSQK"
     CDS             complement(3934..4689)
                     /locus_tag="ctg12_150"
                     /transl_table=11
                     /translation="MDMVKGKIHHLYHSGFAVETENYFLIFDYYMDEVEDNNQVRSLEK
                     GVINPDLLKHKKNVIVFVSHNHGDHFNPVIFNWQEVNPDITYILGDDCIVPSNIRNIYV
                     MRTNQSLELQLHNLVKVKTYGTTDRGVSFLVEVDHLSIYHGGDLNWWHWKSFTPEAQLK
                     EEEDFKKEVNQITESIDIAFVPVDPRLEEYYYLGGEYFAHTIKPKLLIPMHFASNFKIT
                     EEFANKVSNISVPTIVLKERGQVIEYIKA"
     CDS             complement(4783..5598)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AdoMet_dc"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_151"
                     /sec_met_domain="AdoMet_dc (E-value: 4e-33, bitscore:
                     107.3, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVKPLKKLKLYGFNNLTKTLSFNMYDICYAKTVEDRKNYIEYID
                     EQYNAERLTNILTNVANIIGANVLNIAKQDYDPQGASVTMLVSEGLVTSEHTPDHESEA
                     PGPLPDGVVAHLDKSHITVHTYPESHPDEGISTFRADIDVSTCGHISPLKALNYLIHSF
                     DSDIMYVDYRVRGFTRDVTGKKFFIDHKINSIQNYIASETRNRYQMIDVNVYQENIFHT
                     KMILKEFDLDNYLFGINKKDLLPGEKKKIKQRLKKEMAEIFYGRNIPKV"
     CDS             5969..6439
                     /locus_tag="ctg12_152"
                     /transl_table=11
                     /translation="MKMKEQLVKPFLKALQDILNQITGMSMEIIDTNNNADKCFTKDVA
                     IMIGITGQLEGQTIINLDETLAKVIASNMMGGMTVTELDEISKSAVAELGNMVLGNAAI
                     QLSNEGCIIDITPPTLVTKEVNYQVIENQPIVSTVLQNNFGEIEMNLALKVK"
     CDS             6720..7190
                     /locus_tag="ctg12_153"
                     /transl_table=11
                     /translation="MPLNIILFEPEIPQNTGNIARTCVITDTVLHIIGPMGFSLDEKHV
                     KRAGLDYWELLDLRYYDNYEAFLEANPEALIYYCETRTQNIYTDVSYPENCYIMFGKET
                     TGIPKKILEDNLETCIRIPMLQNEKARSLNLSNTVAIVVYEVLRQWRYPNMI"
     CDS             8178..8579
                     /locus_tag="ctg12_154"
                     /transl_table=11
                     /translation="MICKKVTIITNNSNVCGKYDKKYQINYTDGTLLDVLKITRDKIHD
                     GYKLLSHPLSGSVKPNETVYKSVIVSNEKGNLDIESLMFIESAIETAEKFINMKQPPSW
                     NNEILSDFREIDCTLIDSAIESMETYSKI"
     CDS             8620..9573
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_155"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.6e-53, bitscore:
                     172.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIYDVVIIGAGPAGLSAGLYAARAKMSALILEKSKTGGQIAST
                     EEVANYPGSIENASGPSLVARMVEQCKEFGAEMEKDTIVSVKFDEKIKVLVGEKNTYYA
                     RSVIAAPGASPRLLDVPGEKEFTGKGVSYCATCDADFFTDFEVFVVGGGDSAVEEAIFM
                     TRFARKVTIVHRRDELSAAKSIQEKAFKNPKIDFMWDTVITEIKGDGVVEAITLKNVKT
                     GETTEHQAHEDDGTFGIFVFVGYLPQTGIFKDLLDMDKAGYFITDDNMKTNIPGVFAAG
                     DCRVKSLRQVVTAVSDGAIAAVQAEKYVENNFHDEA"
     CDS             9623..9940
                     /locus_tag="ctg12_156"
                     /transl_table=11
                     /translation="MLAVDKDTFEAEVLQAEGYVLVDFWSDGCEPCKALMPDIEALEEQ
                     YGSQIKFVKLNTTQARRLAIKEKVLGLPTISMYKDGSKIEEVTKEDANKGNIEAMIKKY
                     L"
     CDS             10001..11287
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: Glycine_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_157"
                     /sec_met_domain="Glycine_reductase (E-value: 1.6e-247,
                     bitscore: 813.9, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRLELGKIFINDVQFADTTKVENGVLYINKEEMIQVIGGDEHIKS
                     IDIELAHPGEEVRITPVKDVIEPRVKVEGPGGIFPGVLSKVDTVGSGRTHALKNVAVVT
                     AGKIVGFQEGIIDMTGPGAEYTPFSQLHNVVVIAEPIDGLKQYDHEAAVRMIGFKAAEY
                     LGKVAKDLQPDEVKVYETEPIFESAQKYPNLPKIGYVYMLQTQGLLHDTYVYGVDAKKI
                     VPTLLYPTEIMDGAIISGNCVSACDKNPTYVHLNNGIIEELYEQHGKEINFVGVIITNE
                     NVYLADKERSSNWTAKLCRYLGLDGVIVSQEGFGNPDTDLIMNCKKIEREGIKTVIVTD
                     EYAGRDGASQSLADADASANAVVTNGNANETIILPPMKKVIGTTKFVDVIAGGFDGSLR
                     PDGSIEVEIQAITGATNETGFVKLTAKGY"
     CDS             11342..11473
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_158"
                     /sec_met_domain="GRDA (E-value: 1.3e-20, bitscore: 67.1,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIFDGKKIIIIGDRDGIPGPAIEECLKTTGAEVLFSATECFV"
     CDS             11489..11812
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_159"
                     /sec_met_domain="GRDA (E-value: 1.6e-51, bitscore: 167.4,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLENQKRVKDYTEKFGAENVIVILGAAEAESAGLAAETVTAGDP
                     TFAGPLAGVQLGLKVLHAVEGEFKENVDATVFDDQIGMMEMVLDVDAISEEMTNIRNEF
                     SKY"
     CDS             11883..12932
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_160"
                     /sec_met_domain="GRDB (E-value: 3.6e-179, bitscore: 588.7,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKRIVHYINQFFAGIGGEEKADIKPEVREGVVGPGMAINTAMK
                     DDAEIVATIICGDSYFNENVEEAKATIIDMVKEYNPDLFIAGPAFNAGRYGVACGTIAK
                     TVADELQIPVLSGMYIENPGADMFKKSIYITQTGDSAAAMRKAVPDMTALALKLIRGEE
                     VGSPAEDKYIPRGIRKNYFAQERGSKRAVNMLLKKLKGEEFVTEYPMPDFDRVEPMPAV
                     KDLAKAKIALVTSGGIVPKNNPDRIESSSASKYGEYDISSFDNLTEADHETAHGGYDPV
                     YANIDPDRVLPVDVLRDLEKEGVIGELYKYFYTTVGNGTSVANSKAFAAEFAKKLVADG
                     VQAVILTST"
     CDS             12960..13190
                     /locus_tag="ctg12_161"
                     /transl_table=11
                     /translation="MVKEVERAGIPVVHICTVVPISLTVGANRIVPAIAIPHPLGNPAL
                     DANEEKNLRRKIVMKSLEALTTEVDGQTVFE"
     CDS             13374..14645
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_162"
                     /sec_met_domain="ACP_syn_III (E-value: 9.9e-10, bitscore:
                     31.6, seeds: 136, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYSVVKGGGYVLIHTPDMITHNGTTQTTERLVNPDSEYLKKLPN
                     YYRSFEEVISYPPNQAYIGTIKPEDLRNYEMPWYKQKVEGATRTGKHGEIMPQDEFIAL
                     IKMVDVFDLVKLDKEFTGMVKPKMEAHPLMTAELVAKLKDGDDLADIEKFINEEHAEAL
                     YHNDKIVGCVKRAHDIDPNLNAHVIFENLVVKASGVLAFQHLLDKNNVDVTTIDYVIEC
                     SEEACGDMNQRGGGNFAKAIAETVGAVNATGSDTRGFCAAPTHALIEAAALVQSGVFEN
                     VVIVAGGATAKLGMNGKDHIKKEIPVLEDVLGGFAVLISKNDGVHPVLRTDLVGRHKVG
                     TGSAPQNVITALITEPLDKGGLKITDVDKYSVEMQNPDITKPAGAGDVPEANYKMIAAL
                     GVKRGELERTAVNSFVEKHGMPGWA"
ORIGIN
        1 caccttgaac ataattttgt atttctttga ggagttcagg agggagaata tcttttgcgt
       61 ttttataatt caatagagaa ccccctttat agataatagt ctaacttact tttctagaat
      121 catatctgtc caaaattcga aagaagtgaa cccatttttt tcgcatgctt caacagcttc
      181 ataacaatct cgattgaggt agatacaaat tgtctcatta ggttgatctt taagtatttt
      241 tttcagggct tgatttagca gatattctcc aacattacta ttactatagg ctggatgcac
      301 tgtaaaatta tcgatccata tcttatcatt ttctcgggta ggtaggattc cagcaacaat
      361 tttcccttgg gcatccagga taaatttaga gtaagtagta gtaaattctt gcttaaacat
      421 ttcgataaat tcttcaaagg tgcaattagt gaagtattga taatttttag ttgattcatt
      481 tctgtaataa aaatctatta catcttctaa catttcttct gaaaaattta ctacccttag
      541 acttgaattt agaagattta caattggagt aggttctgtt tctgtttcac catcttctaa
      601 cttcatatac atccgatact tagggttaaa accattttta ataattgtag gaattaaata
      661 gtgagaaagg gttgggaaat actcaatttc accatattca agggattgaa tgataaattt
      721 tttcgaatca tcttcacgta aaaaccactc tttaagatta ggaatggact tttcaataat
      781 ttcaaatcgc ttattccagt ttgatggtaa gattagtgta gcccttaatg tatcatcccc
      841 tggagttaaa tgatataaat gatagagaca atactcatca tctacatagt caataagata
      901 tatccccttt tcactaaagg tcttgtattt atcaaagtta tgatagggga ttctaacaaa
      961 gggtaacata gggataaagt gctttttacc atattcaatt ttttctgcaa aatcatgcat
     1021 tgtttccgaa gtaattttta acataattac acctccattg attatttata aataaaatat
     1081 atataaattg taataaaatg ctgtatcttt attttcccat agaacagcta gaaaaaaaag
     1141 gtaaaaaaca agtgtaattg ttttttacca atttaaattt aattatagat gattgtatat
     1201 tttcattaga tgttgtttta agatggggcc ttcttaagaa gaatatcaat tgccttaaac
     1261 attaagcgta tgccttttct atgataacgg aagttattta agcttccaat aaaataggag
     1321 tctgttaaag ggtgataaaa cataaaagaa cctattgaac cggcattacc ccagacatta
     1381 tattttgagg gcatgactaa agggattgtt ttgaagttca ttaatccata accataatcg
     1441 ataccaataa agaacaagtt gaagaagcct gcccaatctt tcatcttttc aaaagtttct
     1501 tccttaataa gtttgtgatg gactaatgcc ttcataaatt ttagtaaatc ttctgcaggg
     1561 gctacaatac ctccacctgc atagtcatcc tttagaatgc taaaatcctt tgcattgacc
     1621 cccttcatat agacatctgc tactgaaata gcactttttt tctttggttc tgaatgactt
     1681 gctagatagg aatggtgcat ttccagaggg ctaaagatat aatagtccat agcttctgct
     1741 aaaggcatct tcgtaatttt ttctaggatt aaacccagta gatgatatcc tgtatcagag
     1801 tagtgaaagc ctcttccggg agggaaatga gtttttaaat ttgattttga ccagagaata
     1861 atctcccgtg gcttccaact tcgatatgga tcatcttcaa tcatttgaag cattgatttc
     1921 ccatttttcg gtgtatcctc aaaataatca tttaatccag aggtatggtt cattaaatgc
     1981 tttattttta tttgatcagt ataatctatg cctttatata tatgcagacc ttttagtagt
     2041 tcttcatcta gatagaggga aatagaatca tcgaagaaaa tttcattttt ttcaactaga
     2101 atgctagtaa gaacagatgt aaaaagcttt ccgatactgg caatgtgaaa aggttggttc
     2161 ggtacagagg ctaccccttc tgtggtacct tctgccatgt ttaggtgaag gttatattta
     2221 tcagaatgaa taagcataaa ggcatttttt atatttttat ctttttgaat tgctttttta
     2281 aagaagtcct taagttggtt ttcaagatga gttttatcca ttaaaatccc tccaatttaa
     2341 actaaaattt aaatgaatac ccattcattt tatttttgaa gctgtagagt agacaatatc
     2401 tcttgcggta tcatctaaaa gtcttttaat gtagttttcg gttatgtttt gtggcaaaag
     2461 attatttgct accattactg aaagtccagt ttgaaagatt cgcatcttaa gaagaatagt
     2521 ctgtagctcc atatcggaaa aatctgcaag ttcagggtct tttctcatct cttcaatcag
     2581 aaattctccc atgtcttcat cataattttt catgtattga ttgctattca tcatcatgtc
     2641 tttaaacagg agactatatt cctttgcaaa cctcaagctg gctacaccga tatcacggaa
     2701 ggggctacct gtattttctt ctaaatatat ttgatgactg atttgatata ctttttttat
     2761 aacttcttct attaattcat cgatattatt aaaattgacg taaatggggg cgatagaact
     2821 tccaagtttt tcagccactt ttctaatagt aatactatta atcccttcta ttttagcaat
     2881 ttcaaagcct gtattaatta ttgcttcttt agaaaatttc tttttcggtg ccatacacat
     2941 cctcctaaag caagtataat gtttgatata taacgtttga tacgtattaa ttatagagca
     3001 tatggaaaat aaaagcaata gcatacaata aaaaaacagg gatctgattc ttcaaattag
     3061 aaattgagac cactgtctat attcaacaaa ataggagata atacaaaaat agaaaaccaa
     3121 ctaagtaaat tataagtagg tgaaactatg tttgggtcat caatttctca attgacagta
     3181 gaactaacga taggtttttt tgctttattt gttgttacta agattacaag aaaatcacaa
     3241 ataaatcaga ttaccccctt tgatttcata tcagctattg ttcttggaga actgctgggt
     3301 aacgcaattt atgatgaaaa ggttagaata tggactatta tgtatgcctt agctctttgg
     3361 ggaattttaa tggtttttat tgaaaaaata acacaaaaat taagaagaac aaggaaatta
     3421 ttagaaggag aaccagcgat tattattaga aatggacaaa ttgattataa cgttataaaa
     3481 aaagaaaaat tagatattaa tgaattgtta agtctattaa ggcaaaagga tgccttttcg
     3541 attcgagaaa tagagtttgc aattttggaa cagagtggga atattagtgt attaaaaaaa
     3601 tctaaatatg aaagtgctac tattgaagat ttaaatctac aagaacatcc tgtatatctg
     3661 ccaattacct taatcctcga tggagagatc ataaaaaata atttatatgc catagggcat
     3721 gacgaaaatt ggttattcaa tcaaattcgt aaagcaggag agaaaaatat agaaaacatt
     3781 ttctatgcag attggaaaca agatgaaggt atccatgttg tacctcgaaa taattctcaa
     3841 aaataatctt aatctaaact aaatttgata tgaccaattt aaaaatatag ctccctttac
     3901 gttacttcat tattcataaa gggagcagct ttattatgct tttatatatt cgattacttg
     3961 accacgttcc tttaaaacga tggtaggaac tgaaatatta gaaactttgt tagcaaattc
     4021 ttcagtaatt ttaaaattac ttgcaaagtg catgggaatc aatagctttg gttttatggt
     4081 atgggcaaaa tattcgccac ctaaatagta atattcctct aaacgtgggt cgacggggac
     4141 aaaggctata tcgatagact cagtaatttg attaacctct tttttgaaat cttcttcttc
     4201 tttaagctga gcttctgggg taaaactttt ccaatgccac caattaagat cgcccccatg
     4261 ataaatactt aaatgatcaa cttccactag aaaggataca cctctgtcgg tggtaccata
     4321 ggttttaacc ttaactaagt tatgtaactg taattctaat gattgattgg tccgcatcac
     4381 ataaatatta cgaatgttag aaggaacaat acagtcatct cctaatatat aagtaatatc
     4441 tggatttact tcttgccagt taaaaattac aggattaaag tgatcaccat gattatggga
     4501 aacaaaaacg ataacatttt tcttatgttt tagcaaatct ggattaataa cacccttttc
     4561 aagacttcta acttgattat tatcctcaac ttcatccatg taataatcaa aaattagaaa
     4621 gtaattctca gtttctacag caaagccact atgataaaga tggtggattt ttcctttaac
     4681 catatccatt agattacctc ctacaattag ttatagtata atgataccag aaattcagta
     4741 aaaataaaca aaaggttaca gattgattct gtaaccttta aattaaacct tgggtatatt
     4801 tcttccgtag aagatttctg ccatttcttt ctttaatctt tgcttaattt ttttcttttc
     4861 accaggaaga aggtctttct tattaatacc gaaaagatag ttgtctaagt caaactcttt
     4921 aagaatcatt ttcgtatgga aaatattttc ttgatataca tttacatcta tcatttggta
     4981 cctatttcta gtttcactag caatatagtt ctgaatagaa ttaattttat gatcaataaa
     5041 gaacttttta ccagttacgt ctctagtaaa gcctcttact ctgtaatcaa catacataat
     5101 atcagagtca aagctgtgaa ttagatagtt taaagccttc aacggtgaaa tgtgaccaca
     5161 tgtagacaca tcgatatctg ctctaaaagt actaattcct tcatccggat gactttctgg
     5221 ataggtatga acagtaatgt gacttttatc aagatgagca accacaccat ctggtaatgg
     5281 accaggagct tcactttcgt gatcaggcgt atgctcagat gttaccagac cttcagaaac
     5341 tagcattgtt acactggcac cctgtgggtc ataatcttgt ttagcaatat ttaatacgtt
     5401 agcaccaata atgttagcta cattagtaag aatattagtt aatctttctg cattatattg
     5461 ttcatcaata tattcaatat aatttttacg gtcttccaca gttttagcat aacagatatc
     5521 atacatatta aaacttaagg tttttgttaa gttattaaat ccatatagtt ttagtttttt
     5581 caacggttta acatccatct tttatttagc aacctccttt gtgtttatct attttaacaa
     5641 ataataatat tatttattat tccttgcgaa ttcaattata aacctcttag agaaatatat
     5701 caagtagtta gaataacata atgaaaatta tattaataat taatgtttat tagataaaat
     5761 tatcaagtaa aattgggagg ataataccta ttactgccaa ttcctctgat atacagcctt
     5821 tttatcaact tcaaattcag ttacagaact taagtgaaaa ggaaaaattg aatgaaaatt
     5881 gtcactcttt acggaaaaat agcaaaaaaa gtcatagata aatctaaatt tatgatataa
     5941 tcacaatagg ataaatcatg gaggtataat gaagatgaaa gaacaactag tcaaaccatt
     6001 cttaaaagcg ttacaagaca tattaaatca aataaccgga atgtctatgg agattataga
     6061 tacaaataat aatgcagata agtgctttac aaaggatgta gcaataatga tcggtattac
     6121 tggacagtta gaagggcaga ccatcattaa tttagatgaa acacttgcaa aggtcattgc
     6181 ttcaaacatg atgggaggta tgactgtaac agaactagac gaaatatcta aaagtgctgt
     6241 tgctgaacta ggtaatatgg tattagggaa tgcagccatt caattgtcta atgaaggatg
     6301 tatcattgac ataacacctc caacgttagt aacgaaagaa gttaattatc aagttataga
     6361 aaaccaacca attgtttcaa cagttctaca aaacaatttt ggagaaattg aaatgaattt
     6421 agctttaaag gtaaaataaa aataatttat tatgggcata aatatctgag gaaattgcat
     6481 catactatca atatgaattt atataggctt tatacaaata tgaaatataa tatattcttc
     6541 attgaataat aaatactaag gttttcattt tgaattaata taaattaata taaatttaaa
     6601 atcaattatg caatctcttg ttctaaatag aattctataa taaggaaact cttataataa
     6661 aatgagattt tcagtaactt tgttagataa gcgtaaatag tagctggagg tagaagaata
     6721 tgccattgaa tattatattg tttgaaccag aaatcccaca aaacacagga aatatagcga
     6781 gaacttgtgt aattacagac accgtattac atattatagg accgatgggc ttctctctag
     6841 atgaaaaaca tgtaaaaaga gcaggactag attactggga gttgttggac cttaggtatt
     6901 atgacaacta cgaagccttc ttagaagcta atccagaggc tttgatctat tattgtgaaa
     6961 cgagaaccca gaatatttat acagatgttt cttatccaga aaattgctat attatgtttg
     7021 gaaaagaaac gacgggtatc ccgaaaaaaa ttctagagga caatctagag acttgcatta
     7081 gaattccaat gctacaaaat gaaaaagcca gatcattaaa cttatcaaat actgtagcca
     7141 ttgtagttta tgaagtatta cgtcaatgga gatatccaaa tatgatttaa gaattgagga
     7201 aattgcacaa ttaataaaag acagatatta atagaaaata aaaaatcttt tcccactggg
     7261 gggacagggg ttttaatatt gtatagaagc aaaataaatt tattaagaat taataaggta
     7321 tcatgcaatt tccttaataa aatgaaaaat ataatttaga tcagtataaa gaataagtta
     7381 cctctaaata tttagacatt gggtaacttt ttttatgcac tcaattattt tttaaactgt
     7441 atttgatttt ttatagtaca taggaaacta tggtctttta atgattataa tcgtcataat
     7501 tttctgtaat gtatttcaac acaagcctac cactaaattt tgcgtaggaa ggctttgttc
     7561 ttgagttcaa ttattattat ttttattatt atgaatttca atagtagcct acaggtctat
     7621 agataagctt ttataaagat cctaaggaat tgtccataaa aaaataaata aataactcac
     7681 aaaaattagg tatatcaata aaaagcataa ataaataaat gcagaattat gataaaaaaa
     7741 taacaaaaaa tacttgctaa tattattccc ctgtaatata atgaaattaa ctaataaatg
     7801 gaataaaaaa tgttttataa taatagttat ttattaataa aacttaataa attaactgaa
     7861 tgatagatgc gggagagact cataatcctt gttggattga gcgccgaagg aagaagctaa
     7921 aaaaagccac tttttagtga acatctcagg caaaaggacc gtgtttggac agtactctgg
     7981 aaagcgggag caccgaagga gcaacttcta tagatactct ggtatattga ggatctgtag
     8041 aaagaatctc tcaggttaaa taaacagaga taactatgca ataggcgttg tcatagttat
     8101 cttttttgta tttttgttag atttaaatag tttgagatag atcacaaatg gatatattta
     8161 taaacggggt gtaaaatatg atttgtaaaa aagtgacgat tattactaac aatagcaatg
     8221 tttgtggaaa atatgacaaa aaatatcaaa ttaactatac agatggtact ttattagatg
     8281 ttttaaaaat aacaagagat aagattcatg atggttataa attattaagt caccccctat
     8341 caggtagtgt taaaccaaat gaaactgttt ataaaagtgt aatagtttct aatgaaaagg
     8401 ggaatctaga tattgaatca ctaatgttca tagaatctgc catagaaaca gctgaaaagt
     8461 ttattaatat gaagcaacca cctagttgga ataatgaaat tttgtcagat tttagagaaa
     8521 ttgattgcac cctaattgat agtgctattg aaagtatgga aacttatagt aaaatataat
     8581 agtacctaaa caatacaaaa gcaaggagtg aatgatttca tggaaaaaat ttatgacgta
     8641 gtaattattg gggcaggccc tgctggttta tcagctggat tatatgcagc tagagcaaaa
     8701 atgtcagcct taattttaga aaaatctaaa actggaggtc aaattgcatc aacagaagag
     8761 gtagcaaatt accctggttc aattgaaaat gcttcaggac cttctctagt agcaagaatg
     8821 gtagagcaat gtaaggaatt tggcgcggaa atggaaaaag atactattgt ttctgttaaa
     8881 ttcgatgaaa aaatcaaggt actagttgga gaaaaaaata catactatgc taggtcagtg
     8941 atagcagcac caggtgctag ccctagatta ttagatgttc caggtgagaa agagtttact
     9001 ggtaaaggtg tatcctattg tgcaacttgc gatgccgact tctttacaga ttttgaagtc
     9061 ttcgtagttg gaggtggaga ttcagcagtt gaagaagcaa tttttatgac tagatttgct
     9121 cgtaaagtta caatcgttca tcgaagagat gaattatcag ctgcaaagtc tattcaagaa
     9181 aaggctttta agaaccctaa aattgatttt atgtgggata cagtaattac agaaataaaa
     9241 ggagatgggg ttgttgaggc cattaccctt aaaaatgtta agacaggtga aacaacagaa
     9301 catcaagccc atgaagatga tggtactttt ggaatctttg tatttgttgg ttatctccca
     9361 caaacaggaa tctttaaaga tctgttagat atggataaag caggatactt tatcacagat
     9421 gataacatga agacaaatat tcctggcgtc tttgcagcag gagactgtag agtaaagtct
     9481 ctaagacagg tggtaactgc agtatcagat ggtgctattg cagcagttca agcagaaaag
     9541 tatgttgaaa ataattttca tgacgaagcg taatcaattt tataatatat gaatttgctt
     9601 tatatttaag gaggtgaaga ggatgttagc agttgacaaa gatacttttg aagcagaagt
     9661 tttgcaggca gaaggatatg tgttagtaga cttttggagt gatggatgcg aaccttgtaa
     9721 agcattaatg ccagatattg aggcattaga agagcaatat ggaagtcaaa ttaagtttgt
     9781 aaagcttaac acaactcaag caagaagact tgctattaaa gagaaggtgt taggtcttcc
     9841 gacaatctcc atgtacaaag atggaagtaa gattgaagaa gttactaaag aagatgcaaa
     9901 caaaggaaac attgaggcaa tgattaaaaa atacttataa tttaatattg ggccttttgt
     9961 aataaaaagg ccctttgata aataaaggga ggtgaagctt gtgcgattag aattaggtaa
    10021 aatctttata aatgatgtac aattcgctga cactacgaaa gtagagaatg gcgtgctata
    10081 cattaataaa gaagaaatga ttcaagtaat tggtggagat gagcacatta aaagtattga
    10141 cattgaatta gctcatccag gtgaagaagt tagaataaca cctgtaaagg atgttatcga
    10201 gccaagggta aaggttgaag gaccaggagg gattttccca ggagtattaa gtaaagttga
    10261 tactgttggt agtggtcgca cacatgcatt aaaaaatgtt gcggttgtta cagctggtaa
    10321 aattgttggt ttccaagagg gaatcatcga tatgactggc ccaggagcag aatatacacc
    10381 cttctcacaa ttacacaatg tagtggtaat tgcagaacct attgatggtt taaaacaata
    10441 tgaccatgaa gcagctgtaa gaatgattgg ctttaaagca gctgaatacc ttggaaaagt
    10501 tgctaaagat cttcaaccag atgaagtaaa ggtttatgaa actgaaccaa tcttcgaatc
    10561 tgctcagaag tatcctaatc ttccaaagat tggatacgtt tatatgcttc aaacacaagg
    10621 acttcttcat gacacctatg tatatggggt agatgcaaag aaaattgtac caactttatt
    10681 atacccaaca gaaattatgg atggggcaat tattagtggt aactgtgttt ctgcttgcga
    10741 taagaaccca acctatgttc acttaaataa tgggattata gaagaacttt atgaacaaca
    10801 tggtaaagaa attaactttg ttggtgtaat catcacaaat gaaaacgttt atcttgctga
    10861 caaagaaaga tcttctaact ggacagctaa actttgcaga tatttagggc tagatggagt
    10921 tattgtatcc caagaaggat ttggtaatcc agacacagac ttaatcatga actgcaaaaa
    10981 gattgaaaga gaaggcatta aaactgttat cgttacagat gaatatgctg gaagagacgg
    11041 tgcttctcaa tcattagctg atgcagatgc aagcgcaaat gccgttgtta caaatggtaa
    11101 tgcaaatgaa accatcatct tacctccaat gaaaaaggtt attgggacta caaagtttgt
    11161 agatgtaatt gctggtggat tcgatggcag tttaagacct gatggtagca ttgaagtaga
    11221 aattcaagcc atcacaggag ctaccaatga gacaggcttt gtaaaattaa cagcaaaagg
    11281 atactaataa ttagataatt ggtaaaaatg ataaatagaa aaatatgaaa ggatggtcaa
    11341 gatgtctata tttgatggaa agaaaattat catcattggc gatagagatg gaattccagg
    11401 tccagctatc gaagaatgtc taaagacaac tggggcagaa gtattattct ctgcaacaga
    11461 atgttttgtc tgaaccgctg caggcgcgat ggacctagaa aaccaaaaga gagttaagga
    11521 ttatactgag aagttcggtg cagaaaatgt tatcgtaatc cttggtgcag ctgaagctga
    11581 atctgctgga ttagcggcag aaactgttac agcaggagat cctacttttg caggtccttt
    11641 agcgggagtc cagttaggac ttaaagtatt acatgcagta gaaggtgaat ttaaagaaaa
    11701 tgtagatgct actgtatttg atgatcaaat cggtatgatg gaaatggtac ttgatgtaga
    11761 tgctatttct gaagaaatga cgaatattag aaatgaattt agtaaatact aattagttag
    11821 gctttacttt attaataaat taacgacaat ttccgcgtat aaatttggag aggggggaaa
    11881 ttatgagcaa aaaaagaatc gttcattata tcaaccaatt ctttgctgga atcggtggag
    11941 aagaaaaggc tgatattaaa cctgaagtaa gagaaggcgt tgttggacca ggtatggcga
    12001 ttaatactgc catgaaggat gatgctgaaa tcgtagcaac catcatttgt ggagactctt
    12061 atttcaatga aaatgtagaa gaagctaagg ctacaatcat tgatatggtg aaagaatata
    12121 atcctgactt gtttatagca ggtccagctt ttaatgctgg tcgttacgga gtagcctgcg
    12181 gtacaattgc taaaactgta gcagacgaat tacaaattcc cgtattatct ggtatgtata
    12241 tagaaaatcc aggggcggat atgtttaaaa agagtatcta cattacccaa acaggagatt
    12301 cagcagctgc tatgagaaaa gctgtcccag atatgacggc tcttgctctt aaattaatta
    12361 gaggtgaaga agtaggttca ccagcagagg acaaatatat tccaagagga attagaaaaa
    12421 attactttgc tcaagaaaga ggttcaaaaa gagctgttaa tatgttatta aagaagctta
    12481 agggtgaaga atttgttaca gaatatccta tgccagattt tgatagagta gaaccaatgc
    12541 cagctgttaa agatttagct aaggcaaaaa ttgctcttgt tacctctggt ggtattgtac
    12601 caaagaataa cccagacaga atcgaatctt ctagtgcttc taaatatgga gaatacgata
    12661 tttctagttt cgataactta acagaagctg atcatgaaac tgcccatggt ggatatgatc
    12721 cagtttatgc taatatcgac ccagatagag tactacccgt tgatgtttta agagatcttg
    12781 aaaaggaagg cgtaattgga gaattgtata agtacttcta cacgacagta ggaaacggta
    12841 catctgttgc caattctaaa gccttcgcag cagaatttgc taaaaaatta gtagcagatg
    12901 gtgttcaagc agttatcctt acctccacct gaggtacctg tacacgttgc ggtgcaacga
    12961 tggtaaagga agttgaaaga gcaggtattc ctgtagtaca catttgtaca gtagtaccaa
    13021 tttctttaac agtaggagct aacagaattg ttcctgcaat agcaattcca catccattag
    13081 gaaatcctgc attggatgct aatgaagaaa agaatttaag aagaaaaatt gttatgaagt
    13141 ctttagaggc tttaacaact gaagtagacg gtcaaactgt atttgaatag aatatgggtg
    13201 ccggttgtta ggagcaaccg gcatttattc tatctccgat aggaaaatta tgtagaataa
    13261 ttgaatcagt cataatttcc tagtcctttg attttagcta ttttaaatag taaaagaggt
    13321 aaacagtcaa acattaagta taaggatgtt taaattattt ggaggtgaat cttatggcat
    13381 attcagtagt aaagggtgga ggatacgttt taatccatac accagatatg attacccata
    13441 acggaacaac acagacaacc gaaagattag ttaatccaga ttcagaatat cttaaaaagt
    13501 tacctaatta ctatcgttca tttgaagaag taattagcta tccgccaaac caagcgtata
    13561 ttggaactat aaagcctgaa gatttaagaa actatgaaat gccttggtat aagcaaaagg
    13621 tagaaggggc aactagaact ggtaagcatg gtgaaattat gccacaggat gaatttattg
    13681 ccctaattaa aatggtggat gtttttgact tagttaaact agataaagaa tttactggga
    13741 tggttaagcc taaaatggaa gcccatccat taatgactgc agaattagtg gctaagttaa
    13801 aagatggaga tgatttagca gatatcgaaa aatttattaa tgaagaacat gcagaggccc
    13861 tataccacaa tgataaaata gttggttgtg tgaagagagc ccatgatata gatccaaact
    13921 taaatgccca tgttattttt gagaacttag tggttaaggc atcaggagtc cttgccttcc
    13981 aacatttatt agataaaaac aacgttgatg ttacaacaat tgattatgtt atagagtgtt
    14041 cagaagaagc ctgcggagat atgaaccaaa gaggtggtgg aaacttcgca aaggcaattg
    14101 cagaaacagt aggtgctgtt aatgcaacag gttctgatac aagaggtttc tgtgcagcac
    14161 caacccacgc tttaattgaa gcagcagcat tagtacaatc gggcgtattt gaaaatgtag
    14221 taatcgtagc cggtggagcg acagcaaaac ttggtatgaa tggaaaagat catattaaga
    14281 aagagatacc agtactagaa gatgtactag gtggatttgc tgtactaatt agtaaaaatg
    14341 atggcgtaca cccagtttta agaacagatc tggtaggaag acataaggtt ggaacaggat
    14401 cagcaccaca aaacgtaatt acagcattaa ttacagagcc actagataaa ggtggtttaa
    14461 agattactga tgtagataag tactcagtag aaatgcaaaa cccagacatc actaagccag
    14521 caggagcagg agatgtacca gaggctaact ataaaatgat tgcagcccta ggggttaaga
    14581 ggggtgaatt agaaagaaca gcagtaaatt ctttcgttga aaagcatggt atgccaggtt
    14641 gggcac
//
