LOCUS       NZ_AP022547.1          23283 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AP022547.1 Klebsiella michiganensis strain THO-011 chromosome,
            complete genome.
ACCESSION   NZ_AP022547
VERSION     NZ_AP022547.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:24:26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2719518
            Orig. end    :: 2742801
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..105
                     /locus_tag="ctg1_2486"
                     /transl_table=11
                     /translation="MSKQGIRALVYVSLVSAMIWGATGYLLVTAVHVL"
     protocluster    1..23283
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2728583:2733155]"
                     /cutoff="10000"
                     /detection_rule="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /neighbourhood="10000"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9066..13637
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /neighbourhood="10000"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protocluster_number="1"
     cand_cluster    1..23283
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((DmsC and Molybdopterin and minimum(2,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or
                     (NrfD and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdop_Fe4S4, Molydop_binding]) and not (Nitr_red_bet_C
                     or Nitrate_red_del)))"
                     /kind="single"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23283
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Molybdopterin_dependent_oxidoreductase"
                     /region_number="12"
                     /rules="((DmsC and Molybdopterin and minimum(2, [Fer4_11,
                     Fer4_4, Molybdop_Fe4S4, Molydop_binding])) or (NrfD and
                     Molybdopterin and minimum(2, [Fer4_11, Molybdop_Fe4S4,
                     Molydop_binding]) and not (Nitr_red_bet_C or
                     Nitrate_red_del)))"
                     /tool="gutsmash"
     CDS             754..1134
                     /locus_tag="ctg1_2487"
                     /transl_table=11
                     /translation="MMFGGFVVFFRCLCFLSYWFSSGFFVFLSGLSFLGGSRFSFCFFV
                     LFSGLRFLGGSGFSGCFFVLFRSLRFLLSSRFRSGGMVFLVVGRFSGGAVSCSSRRRSR
                     GGGSIGSESNRRQTHCSGNDQS"
     CDS             complement(1321..2808)
                     /locus_tag="ctg1_2488"
                     /transl_table=11
                     /translation="MTENKNYHQLTRTFQRLSRFSHLSAIAGWDMFAMMPPGGSAARGE
                     ALAELGVLQHQILTDKKVGEWLQNALQEELNDVEQANLREMTRQYEQAALLPESLVEAK
                     SLAGSRCEHAWRSQRPANDWQGFAENLRDVVKLSREEAQIRAAAKGGSRYDALLDIFEP
                     DMTSARLDVLFADLKSWLPSLLEKVVEKQSQTPLIEPQGPFPIADQRELGLEAMRVLGF
                     DFDGGRLDISAHPFCGGVPQDVRITTRYNENDLLSALFGVIHETGHARYEQNLPRNWLD
                     QPIALARSTAIHESQSLFFEMQLGRSDAFLQRLLPTVRQYFGEQPAFSHENFIAWNQRV
                     KPGFIRVDADEVSYPAHVILRYEIERALIDGDIEVEDIPALWDEKMQHWLGLSTLGNYR
                     DGCMQDIHWTDGGFGYFPSYTLGAMYAAQLMASARRALPQLESDIANGNFSALFDWLRQ
                     NIWQHGSRFTTSQLIQHATGEDLNSDYFRQHLTSRYL"
     CDS             3109..3201
                     /locus_tag="ctg1_2489"
                     /transl_table=11
                     /translation="MNPFTWLFIALLSVDAVRELLGMSSVLGMW"
     CDS             complement(3237..4487)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 95.4; E-value: 1.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2490"
                     /sec_met_domain="MFS_1 (E-value: 9.3e-28, bitscore: 95.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSRTTTVDTAPANDVSDIIAPQPNQFIKRGTPQFIRVTLALFSAG
                     LATFALLYCVQPILPVLSSEFGVSPASSSISLSISTAMLAVGLLFTGPLSDAIGRKQVM
                     VTALVLASCCSLLSTMMSSWHGILMMRALIGLSLSGVAAVGMTYLSEEIHPSVVAFSMG
                     LYISGNSIGGMSGRLLTGVFTDFFGWRIALAVISGFALAAALMFWRILPESRHFRPTSL
                     RPKSLLINFRLHWRDRGLPLLFLEGFLLMGSFVTLFNYIGYRLMLSPWSLSQAVVGLLS
                     VAYLTGTWSSPKAGAMTVRYGRGPVLLFSTAVMLGGLLLTLFSSLWLIFIGMLLFSAGF
                     FAAHSVASSWIGPRARRARGQASSLYLFSYYLGSSMAGTLGGVFWHNYGWNGVGGFIAL
                     MLLAALLTGACLHKRLK"
     CDS             4606..5499
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     77.3; E-value: 2.2e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2491"
                     /sec_met_domain="LysR_substrate (E-value: 2.7e-46,
                     bitscore: 155.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2e-22, bitscore: 77.3,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIELRHLRYFIAVAEELHFGHAAARLNISQPPLSQQIQILEQQI
                     GARLFARTNRSVSLTEAGRQFLADSRQILSQVDDAAARAARLHHGETGELRIGFTSSAP
                     FIKAVSDTLSTFRRRYPDVHIQTRETNTREQIVPLNEGALDLGLMRNTLLPDTLVWERV
                     LREPLLAMVPRDHPLASKPRVSLRELAREPFVFFDPHVGTGLYDDILGLMRRYDLTPAI
                     TQEVGEAMTIIGLVAAGLGVSILPASFRRVQLLEMCWLPIEEQDAVSEMWLVWSKHHEQ
                     GQAARRFRESLLASAT"
     CDS             5633..6853
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ROK"
                     /gene_functions="other (smcogs) SMCOG1034:Repressor, ORF,
                     Kinase (Score: 168.2; E-value: 9.6e-52)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2492"
                     /sec_met_domain="ROK (E-value: 8.3e-50, bitscore: 168.2,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVADSQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRFAQLAPA
                     SITKIVREMLEAHLVQETEIQEPGSRGRPAVGLMVETEAWHYLSIRISRGEIHLALRDL
                     SSALVVEEQLELALQHVQPFASRLLDQVDQFFIRHQKKLERLTAIAVTMPGIIDTEHGI
                     IHRMPFYEDVKDMPLGEILANHTGVSVYIQHDISAWTMAESLFGASRGARDVIQVVIDH
                     NVGAGVITDGRLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVESVLELAQIR
                     MAKSMSSMLHQQPLSVEWLCQAALQGDLLARDIISGVGNHVGRILAIMVNLFNPQKILI
                     GSPFNLAADILFPAISDCIRQQSLPAYSRHIAVESTQFSNRGTMAGAALVKDALYNGSL
                     LIRLLQG"
     CDS             6981..7676
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2493"
                     /sec_met_domain="CbiA (E-value: 2e-12, bitscore: 45.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKRFFITGTDTAVGKTVVSRALLQALAASGKSVAGYKPVAKGSK
                     ETPDGLRNKDALVLQSVSSLVLPYEAVNPIALSEDESSVAHSCPINYGLLSDGLQRLSG
                     QVEHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIANDG
                     LPLIGWVANRINPGLAHYAEIIEVLSKKLPAPLIGELPYLPRAEQRELSQYIDLSILGE
                     VMAVDRIPA"
     CDS             complement(7629..8876)
                     /locus_tag="ctg1_2494"
                     /transl_table=11
                     /translation="MVIAMLVGVLAALAVALFRHAMTGLESLFLSNDSGSLVNAAESLP
                     PWRRLLTPALGGLAAGALLWLWQRRTLARPRAPTDYMEALETGDGVFDTPASLVKSLAS
                     LLVVTTGSAIGREGAMILLAALAASLFARRFTPKEEWKLWVACGAAAGMASAYHAPLAG
                     SLFIAEILFGTLMLASLGPVVIAAVVALLLTNLLNGDSAPLYHVEFHETLSATHYALML
                     ATALLAGLCGPLFIWLMSYSHRCFVRLRLSPPWQLALGGLIVGLLSLLAPAVWGNGYSV
                     VQSYLLSPPLFSAMIVVFVCKLLAVLASSGSGAPGGVFTPTLFVGLGIGMLFASLTGLW
                     LPDYQAIAIVVGLTGMAAFLAATTHAPIMSTLMICEMTGQYVLLPGLLIASVLASVLSR
                     TLRRDSIYRHHLAEYR"
     CDS             complement(9066..9674)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2495"
                     /sec_met_domain="Nitrate_red_del (E-value: 1.3e-23,
                     bitscore: 81.8, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMQSQDRDAVALSARTLGALFSYAPGSEQAAPLVAALRDGSWQSQ
                     WPWPVANGLAAQFALEDDEPLADAWQRLFIGPWALPAPPWGSVWLDKESVLFGDSTLAL
                     REWMRANGIGLSEQRAEPEDHFGTLLLLAAWLCESGQDEAFNQLLAWHLLPWSGRFLSV
                     FIAGAGNPFYQALGQLAQETLTRWQARLPCAVADKPLYR"
     CDS             complement(9715..10572)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: DmsC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2496"
                     /sec_met_domain="DmsC (E-value: 1.3e-96, bitscore: 321.6,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNGWHEWPLVLFTVLGQSVAGAIIVSGLGWLSLNNNSEARQRLV
                     RCMFFIWLVMGIGFLASIIHLGSPLRAFNSLTRVGASALSNEIASGALFFAVGGVWWLL
                     TFLGKMPAILAKAWLLLTMLLGCLFVLEMTLVYQINTVPTWYNAYTTAAFFLTMVLCGP
                     LFAALLLRVANVPFNGTVFASMSVLALLASLAVVILQNSELAEIRSSVQQASALLPNYG
                     WLQILRLAFLALGLGCWICPLASKKNPRIASLLLGLILVLLGEFIGRGLFYGLHMTVGT
                     AIAG"
     CDS             complement(10574..11191)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Fer4_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Fer4_11"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2497"
                     /sec_met_domain="Fer4_11 (E-value: 2.6e-29, bitscore: 99.6,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.001, bitscore: 17.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQYGFFIDSARCTGCKTCELACKDYKNLTPDVSFRRIYEYAGG
                     DWQEDNGVWQQNVFAYYLSIACNHCEDPACTKVCPSGAMHKRDDGFVVVNEEVCIGCRY
                     CHMACPYGAPQYNAAKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIEELREKHG
                     QLAAVAPLPSAHFTRPSIAIKPNANARPCGDTTGYLANPKEV"
     CDS             complement(11202..13637)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Molybdopterin_dependent_oxidoreductase: Molybdop_Fe4S4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2498"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 6.8e-13,
                     bitscore: 46.7, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 1.1e-96, bitscore:
                     322.7, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 7.7e-28,
                     bitscore: 95.1, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQEHTDGLTRRTLIKSTALGSLALAAGGLSLPFSLTHAAAAVQ
                     EAAHGEERIVWGACSVNCGSRCALRSHVRDDEVVWVETDNTGADIYGDHQVRACLRGRS
                     IRRRINHPDRLNYPMKRVGKRGEGKFVRISWEEALDTIADNLKRIVKEYGNEAVYINYS
                     SGIVGGNMTRSSPTASPVMRLMNCYGGSLNQYGTYSTAQIACAMPYTYGSNDGNSTSDI
                     ENSKLVVMFGNNPAETRMSGGGITYYLEQARERSSARMIVIDPRYTDTAAGREDEWIPI
                     RPGTDAALVAGIAWVLINENLVDQGFLDTYCVGYDEKTLPADAPKNGHYKAYILGQGDD
                     GVAKTPQWASRITGIPVDRIIKLAREIGSTRPAYICQGWGPQRQANGELTSRAIAMLPI
                     LTGNVGINGGNSGARESTYTITIERLPVLTNPVKTAISCFSWTDAIDRGPEMTATRDGV
                     RGKEKLDVPIKFIWNYAGNTIINQHSDINKTHEILQDESKCETIVVIENFMTSSAKYAD
                     ILLPDLMTVEQEDIIPNDYAGNMGYLIFIQPVTSAKFERKPIYWILSEVAKRLGEDVHQ
                     KFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKNMGIYKRKDPNGHFVAYRDFRKDPVA
                     NPLKTPSGKIEIYSSRLADIAAKWQLEKDETISPLPVYASTFEGWDDPLREKFPLQMFG
                     FHYKARTHSSYGNVDVLQAACRQEVWLNPLDAEKRGIKNGDMVRVFNARGELRIPAKVT
                     PRIMPGVSAMGQGAWHDANMNGDRIDRGSCINTLTTHRPSPLAKGNPQHTNLVEIEKV"
     CDS             complement(13786..14037)
                     /locus_tag="ctg1_2499"
                     /transl_table=11
                     /translation="MKLSPWLCAALLLGSTAAFAAPDSCERVKSDIQQKIINNGVPESG
                     FSLTIVPNDQPDQPGAQVVGHCANDTFKIIYTRDSGAQ"
     CDS             14140..14850
                     /locus_tag="ctg1_2500"
                     /transl_table=11
                     /translation="VKKRLLLLLAVGALSACDEKGAPQAFTPEMASFSNEFEFDPLRGP
                     VKAFSQTLYDEHDQVVKWVKGRLSSEGCFDLLAFEDRENKTGAALVLDANYYLDAQSHE
                     KRLRLQGKCQLAEMPSAGVSWETDDNGFVVTARGKESTATYCYDREGYPLGKTTIAKGE
                     QFTVASTPSSDPRKKMDYTAVSTFNDRALGNVSQTCDYDSHDNPVSCELKVVDDSVQPA
                     LTRHYTIKSTIDYY"
     CDS             complement(14844..15404)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2501"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4.8e-15,
                     bitscore: 54.1, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAYHVKLRPLEREDLRFVHQLDNNASVMRYWFEEPYEAFVELS
                     DLYDKHIHDQSERRFVIECDGEKAGLVELVEINHVHRRAEFQIIISPDYQGKGLATRAA
                     KLAMDYGFMVLNLYKLYLIVDKENEKAIHIYRKLGFMVEGELIHEFFINGEYRNTIRMC
                     LFQHQYLAEHKPQGQTLLKPTAQ"
     CDS             complement(15467..15808)
                     /locus_tag="ctg1_2502"
                     /transl_table=11
                     /translation="MNTTLNKRWCLTALLALSAVVFTASSFAKTDKLVIESGDSAQSRQ
                     QAAMEKEQWNDTRTLRQKVNKRAEKEWDKADVAFDAQDNCQKSANVNAYWEPNTLRCLD
                     RRTGRTITP"
     CDS             15945..16271
                     /locus_tag="ctg1_2503"
                     /transl_table=11
                     /translation="MLKTTLLFFATALCEIIGCYLPWLWLKRGATPWLLMPTALALALF
                     VWLLTLHPEASGRVYAAYGGVYVCTALLWLRFIDGVKLSHYDWAGALVALCGMLIIVAG
                     WGRA"
     CDS             16478..17692
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2504"
                     /sec_met_domain="MR_MLE_C (E-value: 6.3e-44, bitscore:
                     148.4, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVAAEVFVTCPGRNFVTLKVTTDDGIVGLGDATLNGRELSVAS
                     YLRDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAIDMALWDIKAKAAGMP
                     LYQLLGGASREGVMVYCHTTGHSIDEVLDDYARHKEMGFKAIRVQCGVPGMKTTYGMAK
                     GKGQAYEPATKGQWPEEQLWSTEKYLDFTPQLFAAVREKFGFNEHLLHDMHHRLTPIEA
                     ARFGKSIEDYRLFWMEDPTPAENQACFRLIRQHTVTPIAVGEVFNSIWDCKQLIEEQLI
                     DYIRTTITHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWVPNFGVQ
                     EYMGYSEQMLEVFPHSWTFDNGYMHPGEKPGLGIEFDEKLAAKYPYEPAYLPVARLEDG
                     TLWNW"
     CDS             17707..18726
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2505"
                     /sec_met_domain="ADH_N (E-value: 1.4e-35, bitscore: 119.7,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.3e-15, bitscore:
                     55.8, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSIVIRQPNELVIEERPIPQPAAGEVRVKIKLAGICGSDSHIYR
                     GHNPFAKYPRVIGHEFFGVIDAIGEGVTDKAIGQRVSVDPVISCGHCYPCSVGKPNVCT
                     SLVVLGVHRDGGFSEYAVVPAKNAWQVPDNVTDRHAVMIEPFTIAANVTGHVSPTDQDI
                     ALVYGAGPMGLTTIQVLKRVYRVKQVIVVDRIDERLEMAQRNGADWVINNSVVPLADTL
                     KAEGVLPTLIIDAACHPSILQEAVTLASPAARIVLMGFSTEPSQVAQQGITGKELSIFS
                     SRLNANKFPVVIKWLEQGLINPEELITHQFAYQHVIDALELFENDRKRCCKVLLTFSQ"
     CDS             18770..20146
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 97.3; E-value: 3e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2506"
                     /sec_met_domain="MFS_1 (E-value: 2.6e-28, bitscore: 97.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVKNERTTSDLIRAAVSGWLGTALEFMDFQLYSLGAALVFHEI
                     FFPEQSAAMALILAMGTYGAGYIARIVGAFIFGKMGDSIGRKKVLFITITMMGICTTLI
                     GVLPTYAQVGILAPVLLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSLVAMGT
                     NCGTLSATAIWAVMFFVLDREQLVAWGWRVPFLASVVVMIFAIWLRLNLKESPVFEKVS
                     EDSVLQKEIATQEGTFSAMLKSKSFWLATGLRFGQAGNSGLLQTFLAGYLVQTLLFDKA
                     IPTDALMISSVIGFITIPFLGWLSDKVGRRLPYIIINISAIILAYPMLSIIVDKSYSAS
                     TIMASLIVIHNIAVLGLFALENITMAEMFGSRNRFTRMAISKEAGGLVAVGFGPVLAGI
                     FCNMTGSWMPIVVMLVCYSIIGLISAILMPEVRDRDLSLLNDAADCAPQNKAVGNGQYI
                     "
     CDS             20381..21844
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mannitol_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2507"
                     /sec_met_domain="Mannitol_dh (E-value: 2.7e-49, bitscore:
                     165.5, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Mannitol_dh_C (E-value: 1.6e-98, bitscore:
                     327.4, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHMLLTANATLPAYDRNRLIPRIVHLGFGAFHRAHQAVYADILA
                     TEHGSDWGYTEVNLIGGEQQIADLQLQDLLYTVAEMSADAWTARIVGVVKEAMHAQVDG
                     LESVLAKMCEPQVAIVSLTITEKGYCHSPASGELQLDHPLIVADLQNPHQPKSAPGVVV
                     EALARRKAAGLPAFSVMSCDNMPENGHVMRNVVCAYARAVDAELAEWIARSVTFPSTMV
                     DRIVPAVTAETLEKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPQWEKAGAELVSDV
                     LPFEEMKLRMLNGSHSFLAWLGYLAGYQHINDCMQDENYRRAARALMLEEQAPTLNVQG
                     VDLARYAGLLIERYSNPALKHRTWQIAMDGSQKLPQRMLDSIRWHLAHGGDFTLLAMGV
                     AAWMRYVSGVDDQGQAIEISDPLLPVIAQTVQNSADGEERVRALLGIEAIFGASLPQES
                     RFVNAVVRAYLSLQQHGAKATVAAWAQAN"
     CDS             22122..22553
                     /locus_tag="ctg1_2508"
                     /transl_table=11
                     /translation="MYKKILLPVDVFEMDLSDKAVRHAEFLASADEGEITLLNVLPNSS
                     SSILRGFAADIRKFEAYMREESEKKMKTISRLFSIPAERIHSRVVFGNVRDEILAVSGN
                     EDFDVIVIGSRKPGISTHLLGSNAESILRHAKIPVLVVR"
     CDS             complement(22597..23283)
                     /locus_tag="ctg1_2509"
                     /transl_table=11
                     /translation="MAAEAQLNPTQPVNQQIYRILRRDIVHCLIPPGTPLSEKEVSVRF
                     DVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISLSQVRNGCFVRQAIECAVVRRAAGM
                     VNDEQLYQLEQNLNQQRTAVERQQLTDFFQLDDEFHQKLSQIADCQLAWDTVENIKATI
                     DRVRYMSLDHVTPPDMMLRQHYDIFQPLVARNPDAVEKAMRLHLQEISESVLLVRQENS
                     DWFSEE"
ORIGIN
        1 atgtctaaac aaggtattcg cgcattggtt tacgtttcgc tggtatcagc aatgatttgg
       61 ggcgcgacgg gctatctgct ggtgacggcg gttcacgttc tttaatccgc gacctcaccg
      121 tggtggaacc aggcatgttt aagcggcggg ctgagcgcgt tttgcggcca gcgccgcccg
      181 ttccggcgtt ttattgatag ctaaatcccc gggcaggccg ccggtgttct cgtcagcaaa
      241 atcttcgtcc cttacatttt ctcagcgcta acgctgccgg caatattgcg tgaaggtgcc
      301 gttgcgcagc aggtggcaac aaagcgtagc gggtgatggc aggtttggtg accgcattaa
      361 gcgaccccaa cgatattctc ttttttccgc agtctattca tatcgccgac ggtatcggct
      421 gctgtctggg gctgttgacg gcggtgtggg tgcgtatcga ccggagcgtg ctttcgcttg
      481 atattctggc ggttcgtcgt tggctaacgg cgcgttacgt caaacgtttg acgacggtct
      541 cggcgacaac ctgtggcagc aataggttta gtaaagaaaa aaacggctgg cgaccagcgc
      601 gcagataatc agcaggatca ggatgagctc aaaacgatag cgccgcagca tggtgctctc
      661 cagaaaaaaa cggcgctgaa gccagcgccg atatcatatc acatcgctta acccgggaga
      721 ttaagcagcc ggttgtgcag ctggtttagc ggtatgatgt ttggtggttt tgtggtgttt
      781 tttcgctgcc tgtgctttct gagctactgg tttagcagcg gcttttttgt gtttcttagc
      841 ggcctgagct ttctgggtgg cagccggttt agcttctgct tttttgtgct ttttagcggc
      901 ctgcgctttc tgggtggcag cgggtttagc ggctgctttt ttgtgctttt tcgcagcctg
      961 cgctttctgc tcagcagccg gtttcgcagc ggcggtatgg tgtttcttgt ggtgggtcgc
     1021 tttagcggtg gtgctgtgag ttgcagcagc cggcgccgga gtcgtggtgg tggcagcatc
     1081 ggcagcgaaa gcaacagaag acagacccat tgcagcggca acgaccagag ctaatacttt
     1141 tttcattctg atatcctcga aaaggtttct tgtttcaacc ccactgcggg gccgttgaaa
     1201 gaactatatg cctgtcttat cgaggtttcc gtgagtgttt ggtatcggcg tgtaaccata
     1261 tgtacaacgc gctgctacaa caatgggaca cggcgtcggg cgcggcccga cgccggtgat
     1321 ttacagataa cgcgaggtaa ggtgctggcg gaaatagtcg ctgttaaggt cttctccggt
     1381 tgcatgctga atcagctgcg aggtggtaaa acggctaccg tgctgccaga tattttgccg
     1441 cagccagtca aacagggcgc tgaagttacc gttggcgata tcgctttcca gctgcggcag
     1501 cgcccgtctg gcggaagcca tcagctgagc ggcgtacatc gcgccaagcg tgtaggaagg
     1561 gaaatagcca aaaccgccgt cggtccagtg gatatcctgc atacagccgt cgcgatagtt
     1621 gccgagggtg gaaagtccca gccagtgctg cattttttca tcccacagcg ccggaatatc
     1681 ctcgacctca atatcgccat caatcagcgc gcgttcaatt tcgtagcgca gaataacgtg
     1741 tgccggatag ctcacttcgt cagcgtcgac gcggataaag cctggcttga cgcgctgatt
     1801 ccatgcgatg aagttttcgt ggctaaaggc cggctgttca ccaaagtact ggcgtaccgt
     1861 tggcagcagg cgctgcagga aggcgtcgct acggccaagc tgcatctcga aaaacaggct
     1921 ttgcgattca tggatcgccg tggagcgggc gagggcaatg ggctgatcga gccagttgcg
     1981 cggcaggttt tgttcatagc gcgcgtggcc ggtttcgtga atgacgccaa acagcgcgct
     2041 gagcaggtcg ttttcgttgt agcgcgtggt gatacggacg tcctggggca cgccgccaca
     2101 gaacgggtgg gcgctgatat ccaggcgtcc gccgtcaaaa tcaaatccca gcacgcgcat
     2161 cgcctccagc cccagctcgc gctggtcggc aatcggaaac ggcccttgag gttcgatgag
     2221 cggcgtttgc gactgctttt caaccacctt ctccagcagc gagggaagcc aggatttcag
     2281 gtccgcgaac agtacgtcaa gacgggcgct ggtcatatcg ggttcaaaaa tatccagcag
     2341 cgcgtcgtag cgggaaccgc cttttgccgc agcccgaatc tgcgcctctt cgcgactcag
     2401 tttgacgacg tcacgcaggt tctcggcaaa accctgccag tcgttcgccg gacgctggct
     2461 acgccaggcg tgctcgcagc ggctacccgc cagcgatttc gcttccacca ggctttccgg
     2521 cagcagcgcc gcctgttcgt actggcgggt catttcgcgc aggttggcct gttccacatc
     2581 atttagctct tcctgaagcg cattctgcag ccattcaccc acttttttat cggtcaggat
     2641 ctgatgctgc aaaacgccaa gctcggccag cgcttcgccg cgggccgcgc tgccgccggg
     2701 gggcatcatg gcgaacatat cccagccggc gatggcggaa agatgcgaga agcgggagag
     2761 tcgctggaag gtgcgggtaa gctgatgata atttttattt tcggtcatgt ttacactctg
     2821 acggtggcaa gtgaacaaaa gctttttcgt gggcctacac tatcgcgatc cgccgatggg
     2881 gtcgagggat gcgggcgctt tcgacataaa tcaccccgac gttaatggga aattgcccac
     2941 agcgtcggct cgcccgctcg acgcaagcat cagcataatg tagtgattaa tcgattgcgt
     3001 attttatgtt tggctcgaaa taatccagat gtgcgtaaag tagcagacgc tttctctgaa
     3061 ctacggctaa acttaatgca ggcacaggcc gccgatgcga ggtggattat gaatccgttt
     3121 acctggctgt ttatagcact gctttccgtc gatgccgtta gagaactgtt gggaatgtcg
     3181 tcggtactgg ggatgtggtg aagagcgtgg cccgtttcag gccacgttaa tctgcgttat
     3241 ttcagtcgct tgtgtaaaca cgcgccggtg agcagcgccg ccagcagcat cagcgcgata
     3301 aacccaccta cgccgttcca gccgtagtta tgccagaata cgccgcctaa cgtccccgcc
     3361 atgctggaac ccagatagta gctgaataaa tagagcgatg acgcctggcc gcgggcacga
     3421 cgcgcgcgcg ggccaatcca gctgctggcc accgagtggg ccgcgaagaa acccgcggaa
     3481 aacagcagca tgccgataaa aatcagccac agcgacgaga acagggtcag cagcaggcca
     3541 ccgagcatca ccgcagtcga gaacagcagc accgggccgc gaccgtagcg aacggtcatg
     3601 gccccggctt tcggcgaact ccaggtaccg gtcaaatagg ccaccgatag caggccaacg
     3661 accgcctggc tgagggacca cggcgaaagc atcaggcggt aaccgatata gttaaacagc
     3721 gtcacgaatg accccattaa caagaaaccc tcaagaaaca gcagcggcag cccgcgatcg
     3781 cgccagtgca ggcggaagtt gatcagcagc gattttggcc gcagcgaggt tggacggaag
     3841 tggcgcgatt ccggcaggat gcgccagaac atcagcgcgg ccgccagcgc gaagccgcta
     3901 atgaccgcca gcgctatccg ccagccgaag aaatcggtaa atacccccgt cagcagacgg
     3961 ccgctcatgc cgccaatgga gtttccgctg atataaagac ccattgagaa cgccaccacg
     4021 ctggggtgaa tctcttcgct cagataggtc atgccgaccg ccgccacgcc gctcagcgac
     4081 aggccgatca gggcgcgcat catcaggatc ccatgccagc tggacatcat cgtcgacagc
     4141 agtgagcagc aggaggctag caccagcgcg gtaaccatca cctgtttgcg gccaatggcg
     4201 tcggacagcg gaccggtaaa cagcaggccg accgccagca tcgccgtgga aatcgacagc
     4261 gagatactgc tgctggccgg tgagacgccg aattcactgg agagcaccgg gaggatcggc
     4321 tggacgcaat aaagcagcgc gaacgtcgcc agtccggcag aaaagagggc gagagtgacg
     4381 cgaataaatt gcggagtacc gcgtttgata aactggtttg gctgaggagc gatgatgtcg
     4441 ctgacgtcgt ttgccggggc ggtgtcaacg gtagttgtac gactcacgga aaaatccttg
     4501 ctgatataca gagagttaag tgaccgcaat ggccacttat tcagggtatg aaaatgtaaa
     4561 tattctgtct aatatattaa taatctcaaa taagacgttt taaatatgaa tattgaactg
     4621 cgccatctgc gctattttat tgccgtggcg gaagagctcc attttggcca tgcggcggcg
     4681 cggttaaata tctctcagcc gccgcttagc cagcagattc aaatccttga acagcaaatt
     4741 ggcgcgcgtc tgtttgctcg tactaatcgc agcgtcagcc tgaccgaagc cggaaggcag
     4801 tttctcgccg atagccggca gatcctctcg caggtcgatg atgctgccgc gcgcgcggct
     4861 cggcttcacc acggcgaaac cggcgagctg cgcattggat ttacctcatc ggcccccttt
     4921 atcaaggcgg tttccgacac gctgtcgacc tttcgccgcc gctatcccga tgtacatatt
     4981 cagacgcggg aaaccaacac gcgcgagcag attgtgccgc tgaacgaggg cgcgctggat
     5041 ctgggactga tgcgtaatac cctgctgccg gataccctgg tctgggaaag agtgctgcgc
     5101 gaaccgctgc tggcgatggt gccccgcgat catccgctgg ccagcaagcc gcgcgtaagc
     5161 ctgcgggaac tggcgcggga gccgttcgtg tttttcgatc cccatgtggg taccgggctg
     5221 tatgacgaca ttctgggctt gatgcgccgc tacgacctga cgccagccat cacccaggag
     5281 gtgggggagg caatgacgat tatcggcctg gtggccgccg ggcttggcgt gtcgatttta
     5341 ccggcgtcct tcaggcgggt ccagctgttg gaaatgtgct ggctgccgat cgaagagcag
     5401 gacgcggtgt cggaaatgtg gctggtgtgg tcgaagcatc acgaacaggg gcaagcggcc
     5461 cggcgttttc gtgaatcgct gcttgccagc gccacatgag acatttagga caaataacgg
     5521 ctaaaaatgt gcggtaaatc acaaggctaa gcaaaaattt gacgagtacc gttgaagtgc
     5581 ttcaccatag ccatcagttt atttcgaagc gcgaaaataa agggagtcaa cggtggtagc
     5641 ggacagtcag ccaggccata tcgatcaaat taagcagacc aacgcgggcg cggtttatcg
     5701 cctgattgat cagcttggcc cggtgtcgcg catcgacctc tcgcgcttcg cgcagctggc
     5761 ccctgccagc atcaccaaaa tcgtccgcga aatgctggaa gcgcatctgg tccaggagac
     5821 ggaaatccag gagccaggga gccggggaag gcctgccgtt ggcttgatgg tggaaaccga
     5881 agcctggcac tacctctcta tccgcatcag ccgcggcgag atccacctcg cgctacggga
     5941 tttaagcagc gcgctggtgg tggaagagca gctggaactg gcgttacagc acgttcagcc
     6001 cttcgcgagc cggctgctcg atcaggttga ccagttcttt attcgtcacc aaaagaagct
     6061 ggagcgttta accgccatcg ccgtcaccat gccggggatc atcgataccg agcacggtat
     6121 catccaccgg atgccgtttt atgaagacgt taaggacatg ccgctgggcg aaatcttagc
     6181 caatcatacc ggcgtatcgg tttacattca gcacgatatc agcgcctgga ccatggctga
     6241 atcgctgttt ggcgcctccc ggggagcgcg agatgtgatt caggtggtga ttgaccataa
     6301 cgttggcgcg ggcgtgatca ccgacggtcg tctgctgcac gcgggcagca gcagtctggt
     6361 cgaaatcggc cacacccagg tcgatccgta tggtaaacgc tgctattgcg gtaaccatgg
     6421 ctgtctggaa accattgcca gcgtggagag cgtgctggaa ctggcgcaga tccgcatggc
     6481 gaagtcgatg agctcaatgc tgcatcagca gccgctgagc gttgaatggc tatgtcaggc
     6541 cgcgctgcag ggggatttac tggcgcggga cattatcagc ggcgtcggga accacgttgg
     6601 acggattctg gcgattatgg ttaacctctt taacccgcag aaaatcctta tcggctctcc
     6661 cttcaatctc gccgcggata ttctgtttcc ggcaatatct gattgtattc gacaacaatc
     6721 gttaccagcc tacagccgac atattgccgt ggaaagcacc cagttttcta accggggaac
     6781 gatggctggc gcggccctgg taaaggatgc cctctataac ggatcgctgc tgatacgact
     6841 gttacagggt taacattttt tcatattcac accaaaaatt gcgctatctc aagctggctt
     6901 ccggcagcat cgcgtagact ttttccacag ttgattattt ctctcccgta tatttcatca
     6961 acataactgt ggggttagtg atgtttaagc gtttcttcat aacaggtact gacaccgctg
     7021 tcggcaagac ggtggtttcc cgtgcgctgt tgcaggcact ggctgccagc ggcaaaagcg
     7081 tcgccgggta caagcctgtg gcgaagggca gtaaagagac gccggacgga ctgcggaaca
     7141 aagatgcgct ggtcttacag agcgtgtcat cgctggtgtt accgtatgaa gctgtcaatc
     7201 ccatcgcgtt aagcgaagat gaaagcagcg tggcgcacag ttgcccgatc aactacggac
     7261 tgctgtcgga tggtctccag cgcctcagcg gccaggttga acatgtggtg gttgaaggta
     7321 ccggcggctg gcgcagcctg atgaacgacc tgcgtccgct ttcggaatgg gtggtgcagg
     7381 aacagctgcc ggtgttaatg gtcgtcggca ttcaggaagg ctgtatcaat catgctctgc
     7441 tgaccgcgca ggcgattgcc aacgacggcc tgccgctgat cggctgggtg gccaaccgga
     7501 ttaacccagg cctggcgcat tatgctgaaa tcatcgaggt gctgagcaaa aagctgccgg
     7561 cgccgctgat cggtgaactg ccttacttac cgcgcgcgga gcagcgtgaa ctgagccagt
     7621 atatcgactt atcgatactc ggcgaggtga tggcggtaga tagaatcccg gcgtaacgtc
     7681 cgcgacagca ccgacgccag tacgctggca atcagtaaac cgggcagtaa aacgtattgt
     7741 ccggtcattt cacaaatcat cagcgtggac ataatcggcg cgtgggtggt ggctgccaga
     7801 aacgccgcca tgccggttaa gccaaccact atcgcgatag cctggtaatc aggtagccat
     7861 agtccggtca ggctggcgaa cagcatgcca atccccagcc caacaaacag cgttggggta
     7921 aaaacgccgc ccggcgcgcc ggaaccgctg ctggccagca cggcgagcag cttgcagaca
     7981 aacaccacaa tcatggcgct gaagagcggc ggcgaaagaa gatagctttg cacaacgcta
     8041 tagccatttc cccagacggc cggcgcgagc agcgacagca gaccgacgat aagtccgccc
     8101 agcgccagct gccacggagg cgacaggcgc agccggacaa agcaccggtg gctatagctc
     8161 atcagccaga taaacagcgg cccgcaaagc ccggccagca gcgccgtcgc cagcatcagc
     8221 gcatagtgcg tcgcgctcag ggtttcgtgg aattcaacgt gatacagcgg agccgaatcg
     8281 ccgttcagca gattggtcag cagcagggcc accaccgcgg caatcaccac cgggccaagc
     8341 gacgccagca tcagggtgcc gaataagatc tcggcgataa acaggctccc ggccagcgga
     8401 gcgtggtaag cgctggccat cccggcggcg gcgccgcagg ctacccatag cttccactct
     8461 tcttttggcg taaagcggcg ggcgaacagc gacgcggcca gcgccgccag caggatcatc
     8521 gccccctcgc gaccgatggc gctgccggtc gtcaccacca gcagagaggc cagcgatttt
     8581 accaggctgg ctggcgtatc aaacacaccg tcgccggtct cgagcgcttc catatagtcg
     8641 gttggtgcac ggggccgcgc aagggtgcgg cgctgccaga gccagagcag ggcgccagcc
     8701 gcaaggccgc caagcgcggg cgtcagcaac cgacgccatg gtggcaacga ctcggcggcg
     8761 ttcaccaggc ttccgctgtc attgctcaga aacaggcttt ccagaccggt catcgcatgg
     8821 cgaaacaggg caaccgcgag cgcggcgagg acgccgacca gcatggcgat aaccatgcgg
     8881 cgaaacataa cctgaacatc aggataagcg tgaagacgat gcatcagcga attcggttaa
     8941 cggggaatgg ggcttatttt taccgggaat aagcatagac gcaaaagcga taagtgcgaa
     9001 agaggctaaa ggtgacgttg tcactaaatg cgttatgccc ggcgggcggg cataacgtca
     9061 gggcattagc ggtagagcgg cttatccgcg accgcgcagg gcagccgcgc ctgccatcgc
     9121 gtcagcgttt cttgcgccag ctgaccaaga gcctgataaa aagggtttcc cgccccggca
     9181 ataaacacgc tcagaaagcg gcccgaccac gggagaagat gccaggccag aagctggtta
     9241 aatgcctcat cctgaccgga ttcacaaagc caggccgcca gcagcagcag cgtaccgaag
     9301 tggtcttccg gttcagcgcg ttgctcagac aaaccgatgc cgttagcccg catccactcg
     9361 cgcagcgcca gcgtagagtc gccaaacagc acgctttctt tatccagcca gacggagccc
     9421 cacggcggcg caggcagcgc ccacgggccg atgaacagcc gctgccaggc gtccgccagc
     9481 ggttcatcgt cttcgagagc gaactgcgcc gccaggccgt tcgcgaccgg ccagggccac
     9541 tgactttgcc agctgccgtc gcgcagggcg gcaaccagcg gagcagcctg ctcgctgccc
     9601 ggagcatagg agaacaatgc ccccagcgta cgggcgctga gtgcgacggc atcgcggtct
     9661 tgcgattgca tcatatctat tccttactgc agagggtgcc gcggcaccca ttcattaacc
     9721 ggcaatcgcc gtaccgacgg tcatatgtag gccataaaac aggccgcgac cgataaactc
     9781 gccgagtaat accagtatca gtccgagcag caggctggcg atgcgcgggt ttttcttact
     9841 tgccaacggg cagatccagc agccaaggcc cagcgccaaa aatgctaaac gcaggatttg
     9901 tagccagccg tagtttggca gcagggcgct ggcctgctgc acggaactgc ggatctccgc
     9961 cagttcgctg ttctgcaaaa tgaccacggc caggcttgcc agcagcgcga ggacgctcat
    10021 cgacgcgaag accgtgccgt taaaaggcac gttggctacc cgcagcagca gggcggcgaa
    10081 aagcggcccg cacagcacca tcgtcaggaa gaaggcggcg gtggtgtagg cattatacca
    10141 ggtcggcacg gtattaattt gatagaccag ggtcatctcc aggacgaaca ggcagccgag
    10201 cagcatggtg agcagaagcc aggccttggc caggattgcc ggcattttgc cgagaaacgt
    10261 cagcaaccac cacactcctc cgacggcgaa aaacagcgcg ccgctggcga tttcattact
    10321 taacgccgat gcgccgaccc gggtaagaga gttaaatgcc cgcagcggcg agccgaggtg
    10381 gataatcgac gccagaaagc caatccccat gaccagccag ataaaaaaca tgcagcgcac
    10441 caggcgctgc cgggcttcgg agttattatt cagcgaaagc cagccgagcc cgctgacgat
    10501 tatcgcccct gcaacgcttt gccccagcac cgtaaacagc accagcggcc attcatgcca
    10561 tccatttccc attttacacc tccttcggat tggccagata gccggtggta tcaccgcacg
    10621 gacgcgcgtt ggcgttcggt ttgatcgcga tactcggcct ggtgaagtgc gcggacggca
    10681 gcggggcgac ggcggcaagc tgaccgtgct tttcgcgcag ttcttcgatg ggaccaaagt
    10741 cgagcgcccg cagcgggcag gactcgacgc aaatcggctt tttaccctcg gcgacccggt
    10801 catagcagcc gtcgcatttg gtcatatggc cctttgccgc gttgtactgc ggcgcgccgt
    10861 acgggcaggc catatggcag tagcgacagc cgatgcatac ctcttcgttc accaccacaa
    10921 agccgtcatc gcgcttgtgc atggcgccgc tggggcacac ttttgtgcag gccgggtctt
    10981 cgcagtggtt gcaggcgatg gacaggtaat aggcgaagac gttttgctgc cacacgccgt
    11041 tgtcctcctg ccagtcgccg cccgcgtatt cgtagatgcg gcgaaagctt acgtcaggcg
    11101 tgaggttttt ataatccttg caggccagct cgcaggtttt acagccggtg cagcgggcgg
    11161 aatcgataaa aaatccatac tgagcgctca tggtttactc cttaaacctt ctcgatttcg
    11221 accagattgg tgtgctgcgg attgccttta gccagcggcg aaggacggtg cgtcgtcagc
    11281 gtattaatac aggagccgcg atcgatacga tcgccattca tgttggcgtc atgccaggcg
    11341 ccctggccca tcgccgacac gccgggcatg atgcgcgggg tcaccttagc cggaatgcgc
    11401 agctcgccgc gggcgttgaa tacgcgcacc atatcgccgt tcttaatccc gcgcttttcg
    11461 gcgtccagcg gatttagcca cacctcctga cgacaggccg cctgcaggac atccacgttg
    11521 ccgtagctgg agtgggtacg tgctttatag tggaagccga acatttgcag cgggaatttc
    11581 tcgcgcagag gatcgtccca tccttcgaaa gtagaagcgt ataccggtaa tggactgatg
    11641 gtttcgtctt tttccagctg ccatttggcg gcgatatccg ccagacggct ggagtagatc
    11701 tcgattttac ccgacggtgt ttttagcgga ttggcgaccg ggtctttgcg gaagtcgcgg
    11761 taggccacaa agtgaccgtt ggggtcttta cgtttgtaaa ttcccatatt tttcagttca
    11821 tcgtagctcg ggagcgccgg gtctttcgcc agcatcttcg cgtacaaatg ctgcagccac
    11881 tgctcctggg tacggccttc ggtaaacttc tggtggacat cctcgccaag ccgttttgcc
    11941 acttcgctga ggatccagta gataggtttg cgctcgaatt tagcggaggt aactggctga
    12001 ataaagatga gatagcccat attgccggcg tagtcgttgg gaataatgtc ttcctgctcg
    12061 acggtcatca ggtccggcag caggatatcg gcgtatttgg ccgaggaggt cataaagttt
    12121 tcgataacca cgatcgtctc gcacttgctt tcgtcctgca ggatctcgtg ggtcttattg
    12181 atatcggagt gctggttaat gatggtattg ccggcgtagt tccagatgaa tttaatcggc
    12241 acgtccagct tctctttccc tcgaacgccg tcgcgggtgg cggtcatctc cgggccgcga
    12301 tcgatggcgt cggtccagct aaagcaggag atggcggttt tgaccgggtt ggtcagtacc
    12361 ggcaggcgtt caatggtgat ggtataggtg gattcgcggg cgccgctgtt gccgccgtta
    12421 atgccgacgt tgccggtcaa aataggcagc atggcgatcg cccgggaggt cagctcgccg
    12481 ttagcctggc gctgtggtcc ccatccctgg caaatgtaag ccggcctggt gctgccgatt
    12541 tcccgggcca gcttgatgat gcggtcgacg ggaatgccgg tgatccgcga ggcccattgc
    12601 ggcgttttcg ccacgccgtc atcgccctgt ccaagaatat acgctttgta atgcccgttc
    12661 ttcggggcat ctgccggcag cgttttttca tcgtagccga cgcagtacgt atcaaggaac
    12721 ccctgatcga ccagattttc attaatcagc acccaggcga tgcccgccac cagcgcggcg
    12781 tcggtgccgg ggcgaatcgg gatccactca tcctcccgcc cggcggcggt gtccgtgtag
    12841 cgcgggtcga taacgatcat ccgcgcactg gagcgctcgc gcgcctgttc taaataataa
    12901 gtaataccgc cgccgctcat gcgggtttcc gccgggttat tgccgaacat caccaccagc
    12961 ttgctgtttt cgatatcgga ggtgctgttg ccgtcattgc tgccgtaggt gtagggcatg
    13021 gcgcaggcaa tttgcgcggt actgtaggtc ccgtactggt ttaacgaacc gccgtagcag
    13081 ttcatcaggc gcataaccgg tgaggcggtg ggcgacgatc gcgtcatatt gccgccgaca
    13141 atcccggagg agtagttaat ataaaccgct tcgttgccat actctttgac gatgcgtttg
    13201 agattgtcgg cgatcgtatc cagcgcctcc tcccagctaa tgcggacaaa cttgccttcg
    13261 ccgcgtttgc cgacgcgctt catgggatag ttaaggcggt cgggatgatt aatgcggcgg
    13321 cggatggatc ggccgcgcag gcaggcgcgc acctggtgat cgccataaat atccgcgccg
    13381 gtattgtcgg tttcgaccca gacgacttca tcgtcacgca cgtgtgaacg cagggcgcag
    13441 cggctgccgc agttgaccga acaggcgccc cagacgatac gctcctcgcc gtgagcggct
    13501 tcttgcaccg cggcagcggc gtgagtcagg ctgaaaggca gcgataaacc gccggcggcg
    13561 agagccagcg agccaagggc ggttgatttg attagcgttc gacgggtaag gccgtcggta
    13621 tgttcctggt tagacattgc tcactccatg attttgttat aatggcgtaa tgccaacgcc
    13681 ttcgtaaggt cggcgtggag agtgaggaat catacttaaa atggagtaga gagatcttat
    13741 ccctggtcaa ccgagggata agacttctcc agacattcgg cgaggttact gcgcaccgct
    13801 gtcgcgggta tagatgattt taaaggtgtc gttggcgcag tggccgacaa cctgtgcgcc
    13861 gggctgatcg ggctggtcgt tcgggactat cgtcaggctg aagcccgatt ccgggacgcc
    13921 gttgttgatg attttttgct gaatatcgct ttttacccgc tcgcaggaat ccggcgccgc
    13981 gaaagcagct gtcgaaccca gcagcagagc cgcacatagc cagggtgata gtttcatcat
    14041 aaactcctta ttaacgttat ccagatttaa gcatagcaga agtggtgtaa acaattgtat
    14101 ttgctaatat gattgaacta tgcacaaaag gaatcgcgcg tgaaaaaacg gttgttgctg
    14161 ttactggctg tcggggctct tagcgcctgc gatgaaaagg gcgcgccgca ggccttcacc
    14221 ccggaaatgg ccagcttttc taacgaattt gagttcgatc cgctgcgcgg gccggtgaaa
    14281 gcgtttagcc agacgctgta tgacgaacac gatcaagtgg tgaagtgggt taaagggcgt
    14341 ttatccagcg aaggatgctt tgacctgctg gcatttgagg atcgggagaa taaaaccggc
    14401 gcggcgttgg tgctggacgc taactactac ctggatgcgc aaagccacga aaagcgcctg
    14461 cgtttacaag gcaaatgtca gctggcggaa atgccctcgg cgggggtctc ctgggaaacc
    14521 gatgataacg ggtttgtcgt caccgctcgc ggcaaggaga gtacagcgac gtactgctac
    14581 gatagagaag gctatccgct gggcaaaacc accatagcca aaggtgaaca atttacggtg
    14641 gcctcaacgc cgtcatccga tccgcgcaaa aaaatggact acaccgcagt gagcaccttc
    14701 aatgaccgcg cgctgggcaa cgtaagccag acctgcgatt acgacagtca cgacaacccg
    14761 gtaagctgcg agcttaaggt tgtcgacgac agcgtgcagc ctgcgttaac ccgccactac
    14821 accatcaaaa gcactattga ctattactga gccgtcggtt tcagcagcgt ctggccctgc
    14881 ggtttatgct cggccagata ctggtgctgg aacaggcaca tgcggatggt attgcggtat
    14941 tcgccgttaa taaagaattc atgaatcagc tcgccttcca ccataaatcc gagcttgcgg
    15001 tagatgtgga tcgctttttc attttcttta tcgacgatga ggtagagctt atacaggttg
    15061 agcaccataa agccgtaatc catcgcgagc ttagcggcgc gggtggccag acctttcccc
    15121 tgataatcgg gagagataat gatctgaaac tcggcgcggc ggtgcacgtg gttgatttca
    15181 accagctcaa ccagtccggc cttttcgccg tcgcattcaa tgacaaagcg gcgttcgctc
    15241 tgatcgtgaa tgtgtttgtc gtacaggtcg gaaagctcaa caaaggcttc atagggctct
    15301 tcaaaccagt agcgcataac gctggcgttg ttgtcgagct ggtggacaaa gcgaaggtct
    15361 tcgcgctcaa gcgggcggag tttgacgtga taagcgtcag tcatgggagt acctgtgtgt
    15421 tatagcgaag ttttggtgat tgtggcgccc gtgcgggcgc cattcattac ggggtaatgg
    15481 tgcgaccggt gcggcggtca aggcagcgca gggtgttagg ctcccagtac gcgttgacgt
    15541 tcgcgctctt ctggcagttg tcctgggcgt caaaagccac gtcggcttta tcccactctt
    15601 tttcggcgcg cttgttgacc ttctggcgta aagtgcgggt gtcattccac tgctcttttt
    15661 ccatggcggc ctgctggcgg ctctgggcgc tgtcgccgga ttcgatgacc agcttgtccg
    15721 ttttggcgaa tgacgatgcg gtaaagacca ccgcgctcag cgccagtagg gcagtcaggc
    15781 accagcgttt gttcagtgtt gtgttcatca cgatttcctt taagcgattc ccttggattg
    15841 agtttactac atctcctttc gacggcatac ccgacaaaac agagtaaacg acggccatta
    15901 ttgcgtagaa tgcgttaacg cttgttcaac ttacgacgct ttgcatgtta aaaaccacgc
    15961 tgcttttctt tgctaccgcc ctgtgcgaaa tcattggctg ctatttaccc tggctctggt
    16021 taaaacgcgg ggcgacgccc tggctgctga tgccgacggc cctggcgctg gcgctttttg
    16081 tctggcttct gacgctgcac cccgaggcca gcggacgggt ttatgccgct tacggtgggg
    16141 tatacgtgtg tactgcgctg ctgtggctgc gctttatcga tggcgtcaaa ctcagccact
    16201 atgattgggc cggcgcgctg gttgcgctgt gcggcatgct gattattgtg gccggctggg
    16261 gacgcgcata gccttcttat actgagtgag ccgggccagg tgatgctgtc ccggcccatc
    16321 tcttcctgcc ttctcgctcg ctttctctgt tcacgccgct tttatccccg atgagatact
    16381 gtgatctgcc gcgtcttttt cgatcgttat acttgtatgg tagtaggtct gatggtttac
    16441 ttttacccac taaccgcaca gaagtaagga atgagaaatg aagatcgttg ccgctgaagt
    16501 tttcgtcacc tgtccgggac gcaacttcgt cacccttaaa gtcaccaccg atgacgggat
    16561 cgtcgggtta ggtgacgcga cgctaaacgg tcgcgagctg tccgttgcgt cctatctgcg
    16621 ggatcatctc tgtccgcagc tgattggccg cgacgcgcat cgcatcgaag atatctggca
    16681 gtttttctac aagggcgcct actggcgtcg tggtccggtc acgatgtcgg cgatttccgc
    16741 tatcgatatg gcgctctggg atatcaaggc gaaagccgca ggcatgccgc tctaccagct
    16801 gctgggcggg gcttcgcgcg aaggcgtgat ggtctactgc cacaccacgg gtcactccat
    16861 cgatgaagtg ctggatgact acgcgcgcca caaagagatg gggtttaaag cgattcgcgt
    16921 ccagtgcggc gtgccgggga tgaaaaccac ctacgggatg gcgaaaggta aaggacaggc
    16981 ctacgagccg gcaaccaaag gccagtggcc ggaagagcag ctgtggtcta ccgagaagta
    17041 tctcgatttt acgccacagc tgtttgccgc cgtacgcgaa aaatttggct ttaacgagca
    17101 tctgctgcac gacatgcatc atcgcctgac gccgattgaa gcggcgcgtt ttggtaagag
    17161 tattgaagat taccgcctgt tctggatgga ggatccgacc ccggcggaga atcaggcgtg
    17221 tttccgttta attcgtcagc ataccgtcac gccgattgcc gtcggagagg tgttcaacag
    17281 catctgggat tgtaaacagc tgattgaaga gcagttgatt gactatatcc gcaccaccat
    17341 tacccacgca ggcgggatta cggggatgcg tcggatcgcc gattttgcct cgctttatca
    17401 ggtacgcacc ggttcacacg ggccgtccga tctttctccg gtctgcatgg cggccgcgct
    17461 gcacttcgac ctgtgggtgc cgaattttgg cgtccaggaa tatatgggct attccgaaca
    17521 gatgctggaa gtcttcccgc acagctggac gtttgataac ggctatatgc atccgggtga
    17581 aaaaccgggg ctgggaattg agttcgatga aaaactggcc gcgaaatacc cctatgaacc
    17641 ggcctatttg cctgtagcgc gtctggaaga cggcacgttg tggaactggt aaagaaggaa
    17701 gtcaaaatga aaagtatcgt gattcgccag cccaacgaac tggtgattga agagcgtccg
    17761 atcccgcagc ctgccgcggg cgaagtgcgg gtaaaaatta agctggcggg gatatgcggt
    17821 tccgatagcc atatttatcg cggccacaat ccgtttgcca aatacccgcg cgttattggc
    17881 catgaatttt ttggcgttat cgacgccatc ggagaagggg ttaccgacaa agccatcggc
    17941 cagcgggtca gcgttgatcc ggtcatcagc tgcggccatt gctatccttg ctcggtgggc
    18001 aaaccaaacg tctgcacctc tttggtggtg ctcggcgtgc atcgggatgg cggctttagc
    18061 gagtacgcgg tggtgccggc gaaaaatgcc tggcaggttc cggacaacgt gacggacaga
    18121 catgcggtga tgattgagcc tttcactatc gcggccaacg ttaccgggca cgtttcgcca
    18181 accgatcagg atatcgcgct ggtctacggc gccgggccaa tgggcctgac gaccattcag
    18241 gtgctgaagc gggtgtatcg cgttaagcag gtcatcgtgg tggatcgcat tgatgaacgc
    18301 ctggagatgg cccagcgtaa cggcgcggat tgggtgatta acaacagcgt cgtgcctctg
    18361 gcggatacgc tgaaggcgga gggggtacta ccgacgctga ttatcgatgc ggcctgtcat
    18421 ccctcgattc tacaagaggc ggtcaccctg gcttctccgg cggcgagaat tgttttaatg
    18481 ggattctcga cggagccttc gcaggttgca cagcagggta ttaccggcaa agagctctct
    18541 attttctcgt cgcgtcttaa cgccaataaa ttcccggtgg tcataaagtg gctggaacaa
    18601 ggcttaatta acccggagga gctgattact catcaatttg cttatcaaca tgttatcgat
    18661 gcactggagc tttttgaaaa tgacaggaaa cgttgctgta aggttttatt aaccttcagc
    18721 caataacaac aggtgcggac tctgtattct acaattagag ataatcatta tgactaccgt
    18781 aaaaaatgag agaaccactt ccgatctcat tcgtgcagcc gtatctggtt ggttaggcac
    18841 ggcactggag tttatggatt tccaactcta ttcccttggc gcagcgctgg tattccatga
    18901 gatttttttc ccggagcaat ccgccgccat ggcgctgatt ctggcaatgg gaacctacgg
    18961 cgcgggctat attgcgcgga tcgtcggcgc ctttattttt ggtaaaatgg gcgacagtat
    19021 tgggcgcaag aaggttctgt ttattaccat caccatgatg gggatctgta ccacgcttat
    19081 tggcgtgctg ccaacctatg cccaggtcgg tattttagcg ccggtattgc ttgtgacttt
    19141 acgtattatt caggggttgg gtgccggggc cgaaatatca ggtgcgggta ccatgctggc
    19201 ggaatatgcg ccgaaaggta agcgtggaat tatctcttca ctggtggcta tgggcaccaa
    19261 ctgcggtacg ttaagcgcca cggctatctg ggcggtgatg ttcttcgtgc tggaccgtga
    19321 acagctcgtc gcgtggggat ggcgagtgcc gttcctggcc agcgtagtgg tgatgatctt
    19381 tgccatctgg ctgcgtctca atctgaaaga gagcccggtt tttgagaaag tgagcgaaga
    19441 cagcgtcctg cagaaagaga tagcgaccca ggaaggaacc tttagcgcca tgctgaaaag
    19501 taagtccttc tggctggcga cgggtctgcg cttcggacag gcgggaaatt caggattgtt
    19561 gcaaactttc ctcgcgggct atctggtaca aacattactg tttgataaag ctatccctac
    19621 cgatgcgtta atgattagct ctgttatcgg ctttattacc atcccattcc ttgggtggct
    19681 gtcagataaa gtggggcgtc gcttacccta tattattatt aatatttcag ccattattct
    19741 ggcgtacccc atgctgtcga ttattgtgga taagagctat agcgcgagca ccatcatggc
    19801 gtcactgatc gtcattcata atatcgcggt attgggtctg tttgcgctgg aaaacatcac
    19861 catggcggaa atgttcggtt cacgtaatcg ctttacccgc atggcaattt caaaagaggc
    19921 ggggggatta gtcgccgtag gctttggccc ggtgctggcc ggtattttct gcaatatgac
    19981 cggttcctgg atgcccattg ttgtgatgct ggtgtgctac tccatcattg gcttaatttc
    20041 cgccattctg atgcctgaag tgcgtgaccg cgatctgagc ttgctgaatg acgccgcaga
    20101 ctgcgcgccg caaaataaag cggtgggtaa cgggcagtat atttaaaaaa cacaaactcc
    20161 gcaccgaatg atgatcgccg taaataacat tctgccgggc cattagcccg gcattttcac
    20221 tcttttattc ccagaaatac cgaaagtata actcgtccgt cttcttgtat ggtagttgat
    20281 aaaagtcaaa gatatcatac caattgcatg agatggttta tttcaccagc cggttcccac
    20341 ttaccgtggg gatccagaaa tcataagtat gagagccacc atggaacata tgctattaac
    20401 agcgaacgcc acgctgccag cttacgatcg caaccgtctt attccgcgca tcgttcattt
    20461 gggctttggc gcatttcatc gcgctcacca ggcggtatat gccgatattc tggcgacaga
    20521 acacggcagc gactggggct ataccgaagt gaacctgatc ggtggcgagc agcaaatcgc
    20581 cgatctgcaa ctgcaggatt tactttacac cgtcgccgaa atgtcggcgg atgcctggac
    20641 cgcccgcatt gttggcgtgg tcaaagaggc gatgcatgcc caggtcgatg gtctggaaag
    20701 cgtgctggca aaaatgtgcg agcctcaggt cgctattgtg tcattgacca ttaccgaaaa
    20761 aggctactgc cactcgccgg ccagcggtga actgcagtta gatcacccgt tgattgttgc
    20821 cgatttgcaa aaccctcatc aaccgaaatc cgcgccgggc gtggtggtag aagcgctggc
    20881 acgccgcaag gcggcaggtc tgccggcttt cagcgtgatg tcctgcgaca atatgccgga
    20941 aaacggtcac gtcatgcgta atgtcgtctg cgcctatgcc cgcgccgtcg atgccgaatt
    21001 agccgagtgg attgcgcgca gtgtcacttt cccttctacc atggttgacc gcatcgtacc
    21061 ggcggtgacg gccgaaacgc tggagaaaat tgaacagctc accggcgttc gcgacccggc
    21121 cggcgtcgcc tgcgaaccgt ttcgtcagtg ggtcattgaa gacaactttg tcgccggtcg
    21181 tccgcagtgg gaaaaagccg gcgctgagct ggtgtcggac gtgctgccct ttgaagagat
    21241 gaagctgcgc atgctgaacg gcagccactc gtttcttgcc tggctgggct atctggcggg
    21301 ataccagcat attaatgact gtatgcagga cgaaaactac cgtcgcgccg cgcgtgcgct
    21361 gatgctggag gagcaggcgc cgacgctgaa cgtgcagggt gtggatctgg cacgctatgc
    21421 cggtctgctg atcgagcgct atagcaaccc ggcgctgaag caccgcacct ggcagatagc
    21481 gatggacggc agtcagaaac tgccgcagcg gatgctggat tcgattcgct ggcacctggc
    21541 gcatggcggc gactttacgc tgttggcaat gggcgtcgcg gcctggatgc gctatgtcag
    21601 cggggtggat gaccaggggc aggcgattga aatctccgat cctttactac cggtgattgc
    21661 gcaaaccgta cagaatagcg cagacggcga agaacgcgtg cgcgcgctgc tgggtattga
    21721 ggctattttc ggtgccagcc tgccccagga gagccgtttc gtgaacgcgg tggttcgcgc
    21781 ttatttatcc ctgcagcagc acggcgcaaa agcgaccgta gcggcctggg ctcaggcaaa
    21841 ctaatttatt tcacccgcgt gccgccggtc ccggcggcat tgccctcatg ctttatccct
    21901 gaacgctttt cccgccagaa atatatttcg cgtcaggcgc aatctttgat ccagatcgtt
    21961 gaatatacat aactttatct aacaacagtt aagtataaat aactgatgtt tattttaatg
    22021 aattaaatat ttatctgggt gattattcat tctcctggtg aagtaaatat ggcatgatga
    22081 gttaacttac taagtttcct cagaaaaaag gagaacggac tatgtacaaa aaaattttgc
    22141 tgcccgtaga cgtttttgaa atggatttaa gtgacaaagc ggttcgccat gctgagtttt
    22201 tagcatcagc ggatgaaggg gagattacgc tgctcaacgt tctgccgaac agcagcagct
    22261 caattttacg cggttttgcg gccgatatac gtaagtttga ggcctatatg cgtgaggaat
    22321 cggagaaaaa gatgaagaca atatcccgtc tgttctccat tcccgccgag cggattcatt
    22381 ccagagtggt ctttggcaac gtgcgcgatg aaattctggc ggtgagcggc aatgaggatt
    22441 ttgacgttat cgttattggt tcccgcaagc cgggtatatc cactcatctt cttggttcaa
    22501 acgctgagtc gattttacgt cacgctaaaa taccggttct ggttgtcagg taagtcaatt
    22561 tctcgcggca gataacctgt tctgccgcaa ctcgttttat tcctcgctga accagtcgct
    22621 gttttcctga cgaacaagca gcacggactc gctaatttct tgcagatgca ggcgcatggc
    22681 tttttcaacc gcatccggat tgcgggcgac cagcggctgg aaaatatcat agtgctgacg
    22741 cagcatcata tcgggtgggg tcacatgatc gaggctcata tagcgcaccc ggtcaatggt
    22801 ggctttaata ttctcgacgg tatcccaggc gagctggcag tcggcgattt gcgagagctt
    22861 ctggtgaaat tcgtcatcca gctggaaaaa atccgttaac tgctgccgct ccaccgccgt
    22921 acgctgctga ttgagatttt gctcaagctg gtagagctgt tcatcattca ccattcctgc
    22981 ggcgcgtcgc accacggcgc attcgatggc ctggcggaca aaacagccgt tacgcacctg
    23041 cgagagcgag attttattca catagctgcc gcgctgcgga cggatctgaa ttaagccatt
    23101 ttcagccagt ttgataaaag cttcgcgtac cggttgccgg gaaacgtcaa agcgcacgga
    23161 gacttctttt tccgaaagag gggtgcctgg cgggatcaga caatggacga tatcccgacg
    23221 caggatacga taaatttgct gattaacggg ctgtgtcgga ttcagttgtg cttctgcggc
    23281 cat
//
