LOCUS       NZ_CP021395.1          21181 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP021395.1 Bordetella hinzii strain SV2 chromosome, complete
            genome.
ACCESSION   NZ_CP021395
VERSION     NZ_CP021395.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:38:39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3139023
            Orig. end    :: 3160204
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..198)
                     /locus_tag="ctg1_2900"
                     /transl_table=11
                     /translation="MEATVINLNNTTRLTDELERQLMLQAMEEQFRPHPLRALAHGLRK
                     LGHGIKALFGKTDSAAHTAA"
     protocluster    1..21181
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3148419:3150928]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9397..11905
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..21181
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21181
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="11"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(420..2009)
                     /locus_tag="ctg1_2901"
                     /transl_table=11
                     /translation="MSQDENDRPRKTLTIKAKPAPAKDEQSDRPSRKRSGARARQAAQI
                     ERAQQAHKRPGDPPPRTPETEAGYAERPAQRRKPLPYASAERGTRSRGDDGAGENRRRS
                     GMGVVRAEPAPDWDDVFAAEDAPVSDTPQAQRRPRHPGRQAETFRCYAPCPQGLEEALT
                     AEMQALGFDDAQAGRAGCAFSTDWSGIQRANLYSRLATRILVQVGQGDLDHEDDLLDLA
                     YSVPWERWFGPEDTLRVDTSAIKSPVHSLQYCNLRVKDGICDRLRDREGARPSIDTVRP
                     DARVQLFMEGTHATLYLDTSGESLFKRGWRLDKGEAPLRENLAAGMLALAGWDPAAPLV
                     DPFCGSGTILIEAAWIALGVPPGISRPFGFERMRQHDARRWRDLKDDARSRIRTQLDTP
                     IVGYDIDERAIEFARANAERAWLTDETIRFEVGDARHIQAPASEGWIVTNPPYGERMEI
                     ADEFWREWSACLKRQFAGWQAHVISSDMKLPQRMRLKPVRRIPLHNGSLDCRLFAFELV
                     PAGYRDGAGGTV"
     CDS             complement(2037..2465)
                     /locus_tag="ctg1_2902"
                     /transl_table=11
                     /translation="MGMLWVKTFHIVFIASWFAGLFYLPRIFVNLAQQSDPAIQACLLG
                     MARRLYRFMTILAVPAILLGLWLYVGYRIGVGPGNGWMHAKLFLVLLLIGYHHACGVML
                     RKFEQGRNTRSHKFYRWFNEVPVLLLVVVVALVVLKPF"
     CDS             complement(2518..3963)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2903"
                     /sec_met_domain="MmgE_PrpD (E-value: 1.3e-165, bitscore:
                     549.2, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSASPPSARPDQVLADIADYVIGDDIQSPLAFETARNCLIDTLGC
                     GLEALEYPACKKLLGPIVPGTVVPNGAKVPGTSFQLDPVQAAFNIGAMIRWLDFNDTWL
                     AAEWGHPSDNLGGILATADWLSRSAVAAGKPALTMRDVLTAMIKAHEIQGCLALENAFN
                     KVGLDHVVLVKVATTAVVARMLGLSRDEIINAVSLAWVDGQSLRTYRHAPNTGSRKSWA
                     AGDATSRGVRLALIARTGEMGYPTVLTAKTWGFYDVLFKGQPFRFQRPYGSYVMENVLF
                     KISYPAEFHAQTAVECAMQIHQQLKATGRSAQDIRRITIRTHEACLRIIDKQGPLTNPA
                     DRDHCIQYMVAVPVLFGRLTAADYEDSAAADPRIDALRARILCIEDPAFTRDYHDPDKR
                     SIANALTVEFNDGSRLDEVVCEYPVGHKRRRAEGKPLLEAKFRRNLARMLPARQQQRIL
                     DVSLDPQRLEAMPVHEYVDLYVI"
     CDS             complement(4020..5210)
                     /locus_tag="ctg1_2904"
                     /transl_table=11
                     /translation="MSTSQKKAAPAPAQTEEKAGFKPKKSVALSGVVAGNTALCTVGRT
                     GNDLHYRGYDILDFADAAEFEEIAHLLVHGKLPNKAELKAYKEKLRSLRGLPAQLQTAL
                     ESLPAASHPMDVMRTAVSVLGCVLPEKDDHNTPGARDIADRLMANLGSALLYWYHYSHN
                     GRIIDVQTDDDSIGGHFLHLLHGQKPSDDWVRAMHTSLILYAEHEFNASTFTGRVIAGT
                     GSDMYSAITGAIGALRGPKHGGANEVAFEVQKRYDSPDEAEADIRRRVENKEVIIGFGH
                     PVYTISDPRNKVIKEVARKLSKKAGSTKMFDIAERLETVMWDIKKMFPNLDWFSAVSYH
                     MMGVPTAMFTPLFVIARTAGWSAHIIEQRIDNKIIRPTANYTGPENLKFVPLEKRK"
     CDS             complement(5284..6177)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2905"
                     /sec_met_domain="PEP_mutase (E-value: 2.7e-53, bitscore:
                     178.9, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRPDSPGALFRRALAQEQPLQIIGAINANHALLAKRAGYRAIYL
                     SGGGVAAGSLGLPDLGINTLDDVLTDVRRITDVCDLPLLVDIDTGFGPSAFNIGRTVKS
                     LIKFGAAACHIEDQVGAKRCGHRPGKEIVSTEEMADRVKAAADARTDSDFYLIARTDAI
                     ASHGVDAAIERALACVEAGADAIFAEAAYDLATYRRFVDAVKVPVLANITEFGKTPLFT
                     VEELKSAGVGMVLYPLSAFRAMNKAAEAVYEAIRRDGHQKNVLDLMQTRDELYDRIGYH
                     AFESQLDSLFAKDKSK"
     CDS             complement(6386..7375)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ldh_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ldh_1_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2906"
                     /sec_met_domain="Ldh_1_C (E-value: 4.6e-31, bitscore:
                     106.0, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ldh_1_N (E-value: 2.8e-39, bitscore:
                     132.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKPAMRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIP
                     DEKAQKALKGVIMELEDCAFPLLQEVTAHSDPKTAFKDADVALLVGARPRGPGMERKDL
                     LTVNAQIFTAQGRALNEVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDH
                     NRALSQLAAKSGKAVAGIEKLVVWGNHSPTMYPDYRFATVDGQPLAKLINDETWNRDVF
                     IPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGIPSDGSYGIPEGI
                     IYGFPVTTANGEYTMIKDLEVDAFSRERMDFTLKELLEERDGIKDLLK"
     CDS             7696..8475
                     /locus_tag="ctg1_2907"
                     /transl_table=11
                     /translation="MADPRPDSPLRTRTARQAGEGAAFSPLYRQIKDLLVQSLERGEWK
                     PGELIPSEIDLAARFQVSQGTVRKAVDELAAEHMLLRRQGKGTFVATHHEARVRYRFLR
                     LAPDEAGEGGRAENHVLECRRIRAPAEIARALELRAGETVVSIRRQLAMNHAPVIIDDI
                     WVPGAAFRGLTLDLLKANRVPLYGLFESEFGVSMVRADEKIRAVAASEEVAALLHVTPG
                     TPLLQVDRISYTYGDRPMEVRRGLYLTDHYHYRNSLN"
     CDS             8597..9010
                     /locus_tag="ctg1_2908"
                     /transl_table=11
                     /translation="MSDSAAKPRPQFRNISVPQILSYRLPLAGKLSILHRVSGALLFLC
                     LPLVIVPLFAASVTSPESFAQVAQYAANPLVKLVLLVLIWGYLHHFCAGIRYLVLDLHI
                     GIDKASSRKSAAAVFAVSLVLTLVFALKLFGVL"
     CDS             9010..9393
                     /locus_tag="ctg1_2909"
                     /transl_table=11
                     /translation="MQDTKNFGPKRLVVGAHYGTVDFIAQRLTAIIMAVYTLVLIIGLL
                     VMPAYTYENWKALFTFHVFALPLGQILASLAFFALAWHAWIGVRDIWMDYVRPVGVRLL
                     LQVLTILWLVGTVVYFAQIIWRI"
     CDS             9397..11175
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 394.2; E-value:
                     2.6e-120)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2910"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.9e-118,
                     bitscore: 394.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-38, bitscore:
                     130.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVAVMNSLPRRQFDVVVVGAGGAGMRCSLQLSQAGLSVAVLSKVF
                     PTRSHTVAAQGGVSASLGNMSEDNWYWHMYDTVKGSDWLGDQDAIEFMCREAPNAVYEL
                     EHFGMPFDRNPDGTIYQRPFGGHTANFGEKPVQRACAAADRTGHALLHTLYQRNVAART
                     KFFVEWMALDLLRNEEGDVVGVTALEMETGDIYILEAKTTVLATGGAGRIWAASTNAFI
                     NTGDGLGMAARAGIPLQDMEFWQFHPTGVAGAGVLITEGVRGEGGILLNKDGERFMERY
                     APTLKDLAPRDFVSRSMDQEIKEGRGCGPDGSYVVLKLDHLGADVINKRLPSIREIAIK
                     FGNVDPIKEPIPVVPTIHYQMGGIPANYHGQVLERVNGENKIVNGLYAIGECAAVSVHG
                     ANRLGTNSLLDLIVFGRATGNHIVNSHPERQHAHKPVPKEAVDFSMDRVNKLESRTSGE
                     KTQDVANAIRMSMQRHCGVFRTLDLLNEGVQQIEDLAKVAGSIYFKDKSKVFNTARVEA
                     LELANMTEVARATIKSAANRTESRGAHALNDFPNRDDENWLKHTLWYSEGSRLDYKPVQ
                     MKPLTVESFPPKARTF"
     CDS             11189..11905
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 115.8; E-value: 3e-36)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2911"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-34, bitscore: 115.8,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 2.6e-10, bitscore: 38.7,
                     seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKRIVKFEIYRYDPDKDERPYMQKLEVELQPTDKMLLDALVRI
                     KNDVDDSLALRRSCREGVCGSDAMNINGKNGLACTTNLRELKEPIVLKPLPGLPVIRDL
                     IVDMTHFFNQYHSVSPFLINDTPPPERERLQSPEAREELDGLYECILCACCSTSCPSFW
                     WNPDKFVGPAGLLQAYRFIADSRDEATGRRLDNLEDPYRLFRCHTIMNCVDVCPKGLNP
                     TKAIGKIKELMVRRTV"
     CDS             11931..12191
                     /locus_tag="ctg1_2912"
                     /transl_table=11
                     /translation="MSKLTELQRARLRWRARRGLLENDLIITRYLDANELQLTDEDVSA
                     LTQLFELGDNDLLDLLLARKEPEGALDTPRLRAIIAQMREL"
     CDS             12212..13513
                     /locus_tag="ctg1_2913"
                     /transl_table=11
                     /translation="MNLSDKKATLSLSDGSAPIELPVYKGTLGPDVIDIRKLYGQTGMF
                     TYDPGFMSTAATSSGITYIDGDKGELLYRGYPIEQLAVNCDFLDICYLILNGDLPNGEQ
                     KTDFDSQVTHHTMVNEQLHFFLRGFRRDAHPMAVLTGLVGALSAFYHDSTDITNAQHRH
                     ISAIRLIAKMPTLVAMAYKYSQGQPFIYPQNDLSYTGNFLRMMFATPCEEYKVNEVVER
                     ALDRIFILHADHEQNASTSTVRLCGSSGTNPFAAIAAGVACLWGPAHGGANEACLQMLE
                     ELQANGGVAKVGEFMEKVKDKNSGVRLMGFGHRVYKNYDPRAKLMQETCKEVLGALGLE
                     NDPLFKLAMELERIALEDDYFVQRKLYPNVDFYSGIVQRAIGIPTSLFTAIFALARTVG
                     WIAQWNEMLSDPDYKIGRPRQLYTGSVVRNVPKR"
     CDS             complement(13611..14483)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 36)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2914"
                     /sec_met_domain="LysR_substrate (E-value: 7.8e-39,
                     bitscore: 131.2, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.6e-20, bitscore: 70.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPSPLLVAELKSFYAVARCGSVTKAAAQLGVSQPTVTGQLRQLES
                     RYGIELFYRQGRSLRLSDAGHRLMPLVEQLMLQESEIEFRLRDACELREGNLRIGATGP
                     FYIMDTVRRYNERYPGIELQLTIGNSQSMLQALHEYRIEIATSSYATEDKHLYRRTIAA
                     DPLRVVVHREHPLADRASVSLADLRPYTLLLREPGSMTRQLTEQALAEAGVTPATILEI
                     GSRESIRQAVLCNLGLSLIPAREAPAHPQLAALELSGTRIMMHEYLYCLRERQPVQLIA
                     RFLELAPQT"
     misc_feature    complement(14364..14366)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="gutsmash"
     CDS             14638..15714
                     /locus_tag="ctg1_2915"
                     /transl_table=11
                     /translation="MSLADDTFLSVRNLGKRYGGHTALADVSLDICAGELVCLLGPSGC
                     GKTTLLRAIAGLDPQDSGSIVLSGRDISRAAPAERDYGILFQSYALFPNLTVAQNVAYG
                     LSGQRAHRQRVAARVEEMLDLVGLSGAAGQYPGQLSGGQQQRVALARALAPAPSLLLLD
                     EPMSALDARVRTHLRAELRALQRRLAITTLMVTHDQDEAMEMADRIAVMNGGRIEQFGT
                     PRELYRRPATAFIADFVGEANWLGYERIDAGHVRVGRQVLEVNEAPAAERGRLFLRPEA
                     IRLAESGGLPSANTFLAEVQDGVFLGSNYRLTLRIDGMPGQVLQAIVPPQAGDALLDQY
                     AAGRCWVELPRDALRSYA"
     CDS             15692..17452
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 36.1; E-value: 1.8e-11)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2916"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.8e-12, bitscore:
                     44.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYVPTLEAPAAVSAGKPSPERLQVPARRRLPGWIGRWAALAGQG
                     SYALALVICLALPLAAILARAAMGEQGGLALMRDIVLQSDFLAMVGRSLAVGLTTAAVV
                     VPCAYCYAYGLTRTLMPFKGLLRMLALLPLLAPSLLPGIALIYLLGNQGLLKTWTGGAT
                     IYGFWGIVAGEVFYTFPHALMILVTGLTLADGRLYDAARAMGAGPLRTFLTVTLPGTRY
                     AVFSACCLVFTLAVTDFGVPKVVGGDYNVLAVEAYKAVVGQQNFSKGAAIGLMLLIPAV
                     LTFLLDRRLRTRQGAGLTGRSQRYAPGRHGARDLSFLLAGGCIALMLAALVGVAVWASF
                     IRMWPYNLSLSLRSYDFDNMDGGGWLAWRNSLTLAALTAVIGTALVFGGAWMIEKLPAR
                     GVARPLRGLVSLLALTPMAVPGLVLGLGYIFFFNSPLNPLGGLYGTMALLVICTVVHFY
                     TSAHLTAVTALGALDPEFEAASAALKVPALLTFWRVTLPMCLPAVLATARYLFVSAMTT
                     VSAVVFLYSPSTVLAAVAVLNMDDAGFIGPAAAMCTVIMASSAVVSLLLHGASRALLRR
                     TQDWRMAPRD"
     CDS             17482..18297
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2917"
                     /sec_met_domain="HAD_2 (E-value: 1.4e-10, bitscore: 39.6,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALPTRLEAVIFDWAGTLVDFGSFAPTRVFVEAFAQFGVSLSLE
                     QARGPMGLGKWDHIRALCNEPDIAQQYRQRFGVLPDDAAVTAIYERFLPMQREKVAQYS
                     DVIPGAPDVLRELRARGLKIGSCSGYPASVMDRVLERARAGGIEIETVVASDEVPRARP
                     APGMALKSAVALGIDDVAGCVKVDDTGVGVEEGRRAGMWSVGLLLSGNAAGLGLDAYRS
                     LDEAGRAAARERARQAFAAAEPHYFIDTVAGLPGVLSDISARLARGERP"
     CDS             18328..19359
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 62.5; E-value: 2.2e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2918"
                     /sec_met_domain="SBP_bac_1 (E-value: 1.6e-17, bitscore:
                     62.5, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEFHLLARRAVGLLALAAAPVMAQQTTLTVYTALEADQIKAYQA
                     AFEREYPDIKIQWVRDSTGIITAKLLAEKNNPKADVIWGLAGTSLGLMDKEGMLEPYAP
                     KGLDQISPQMRDAKPVPAWVGMDAFAAAICFNTVEAKKQNLPEPKSWQDLTRPEYAGKI
                     VMPNPASSGTGFLDVSAWLQIFGEDKGWAFMDALHKNIGSYTHSGSKPCNLAASGEFPI
                     GVSFDYRAAKLKADGAPVQPIFPSEGLGWEVEATAIVRGTKNADAARKVADFSASRAAN
                     ELYKANFAVLAIPSVATSNPNLPTDLASRMIKNDFVWAATQRDRIIAEWTKRYDSKSEP
                     KKK"
     CDS             19419..20546
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2919"
                     /sec_met_domain="DAO (E-value: 5.7e-35, bitscore: 119.5,
                     seeds: 522, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDFDAVVVGGGMLGMAHAWACARRGLSVAVVERARQAHGATIRN
                     FGQVLVTGQAPGEMAGLARQTRALWLQLAGQAGFHVRANGCLVLARNAHERDVLEEFAS
                     ERLQTEGYAAQLLSGRELGAFYGGRLDHHCAALRGSDDLQIYSREALPAITRHLAEDMG
                     VRVIHGTLARRAEGGEVHTTAGNLRARHVFVCPGHDYLTLWPELFAPLDLEVSRLQMLR
                     AAFAGQAFSLDMPLLTGLSCVHYGAFSDLPSAQRLRALFEARSPFLMREGIHLLISPTP
                     YGELIVGDSHRYGADAPPFNDEAIDDALLALAQQALGARLRVLERWQGVYGAHGPAPYS
                     VMRADAQTTVAVMHSGVGMTVGLAIGERAVADVLG"
     CDS             complement(20567..21181)
                     /locus_tag="ctg1_2920"
                     /transl_table=11
                     /translation="MPSFLLIASAHFLALLSPGPDFFLVARSALAAGWRTASGACLGIA
                     LANGLFIVLAFGGVSSLRDGGLLLRGLQAAGGAYLVYLGLLFLRHAGRTPLDGQGKAAG
                     SWWRALGMGLFSGVLNPKNALFYASLATLLAPGLSPGRQAAYGLWMFGVVLGWDLLVAV
                     LISRPRVLRRFGRMLPWLERACGLILGAMGAGLLASLALAF"
ORIGIN
        1 tcaggcggcg gtgtgcgcgg ccgagtcggt cttgccaaac agcgccttga tgccgtggcc
       61 cagcttgcgc aggccatggg ccagggcgcg caggggatgc ggacggaatt gttcttccat
      121 cgcttgcagc atcagttggc gttcaagttc gtcggtcagg cgggtggtgt tgttcaggtt
      181 gatcacggta gcctccattg ggctgacttg ttgtgtgtct agggttaacc cgaattatag
      241 ggtttaccct agaccaatgc aagccttgcc gtgcttctgt gcaacatgcg ccttcctggt
      301 gctgataatg ccccaattcg gcgccgctgt ggcccaccca ggcaccttaa tgttgcggca
      361 ttgcagcagt tttacaactt gcgggcgcag ccgcgccgcc cataccccgc caaatccgtc
      421 taaaccgtgc cgccggcgcc atcgcggtag cccgccggca ccagttcgaa ggcaaacagg
      481 cggcagtcca gcgaaccatt gtgcagcggg atgcggcgca ccggcttgag gcgcatgcgc
      541 tgcggcagct tcatgtcgct ggatatcaca tgggcctgcc agccggcaaa ctggcgcttc
      601 aggcaggctg accattcgcg ccagaactcg tcggcgatct ccatgcgctc gccgtagggc
      661 gggttggtga cgatccagcc ttcgctggcc ggggcctgga tgtggcgcgc atcgccgacc
      721 tcgaagcgga tggtctcgtc ggtcaaccag gctcgctcgg cgttggcgcg cgcgaactcg
      781 atggcgcgct cgtcgatgtc atagccgacg atgggcgtat ccagctgggt gcggatgcgc
      841 gagcgggcgt cgtccttgag atcgcgccag cggcgcgcat cgtgctggcg catgcgctcg
      901 aagccgaagg gacgcgagat gccgggcggc acgcccagcg cgatccacgc ggcttcgatc
      961 aggatggtgc cgctgccgca gaagggatcg accagcggcg cggccgggtc ccagcccgcc
     1021 agcgccagca tgccggcggc caggttctcg cgcaagggcg cttcgccctt gtccaggcgc
     1081 cagccgcgct tgaacaggga ttcgcccgag gtgtccaggt agagcgtggc gtgcgtgcct
     1141 tccatgaaga gctgcacccg ggcatcgggc cgcacggtgt cgatgctggg acgcgcgccc
     1201 tcgcgatcgc gcaggcggtc gcagatgccg tctttgacgc gcagattgca gtattgcagg
     1261 ctgtggaccg ggctcttgat ggccgaggtg tccacccgca gggtgtcctc gggcccgaac
     1321 cagcgctccc atggcacgct gtaggccagg tcgagcaggt cgtcctcgtg gtcgagatcg
     1381 ccctggccca cctgcaccag gatgcgggtg gccagccggg aatagaggtt ggcgcgctgg
     1441 atgccggacc agtcggtgct gaaggcgcag cccgcgcggc cggcctgggc gtcatcaaag
     1501 cccagcgcct gcatttccgc ggtcagcgcc tcttccagcc cctgggggca gggggcgtag
     1561 cagcggaagg tctcggcctg gcggcccgga tggcgcggcc ggcgctgggc ctggggcgtg
     1621 tcgctgacgg gtgcgtcctc cgccgcgaaa acatcatccc agtccggcgc cggctcggcg
     1681 cgcaccacgc ccatgccgct gcggcgccgg ttttcccccg ccccgtcatc gccgcgcgag
     1741 cgcgtgccgc gctcggccga agcatagggc aggggcttgc gccgctgggc cgggcgttcg
     1801 gcatagccgg cctcggtctc gggcgtgcgc ggcggcgggt cgccggggcg cttgtgggcc
     1861 tgctgggcgc gttcgatctg cgcggcctgg cgtgcccgcg cgccgctgcg cttgcgggag
     1921 gggcggtcgc tctgctcgtc cttggcaggg gcgggcttgg ctttgatcgt cagcgtcttg
     1981 cgcgggcggt cgttttcatc ttgggacata cgggaaggcc ttggtcggct aggcaatcaa
     2041 aatggcttga ggacgacgag cgccaccacc accacgagca gcaagacggg aacctcgttg
     2101 aaccagcgat aaaacttgtg cgagcgcgtg ttgcgcccct gttcgaactt gcgcagcatc
     2161 acaccgcagg cgtgatggta gccgatgagc aaaagcacca ggaaaagctt ggcatgcatc
     2221 cagccgttgc ccggaccgac gccaatgcga tagccgacat agagccacag gcccagcaga
     2281 atggcaggca cggcgaggat ggtcatgaag cggtagaggc ggcgtgccat gcccagcaga
     2341 caggcctgga tggcggggtc ggattgctgc gccaggttca cgaagatgcg tggcaggtag
     2401 aacagccccg cgaaccacga agcaatgaag acgatgtgaa aagtcttgac ccaaagcatg
     2461 cccatggtgc gcgtccttat tcgaaaacac gccattgtag gcgacagaaa agcggagtca
     2521 gatcacatag aggtcgacat attcatgcac cggcatggct tccagccgct gcgggtcgag
     2581 cgagacgtcc aggatgcgct gctgctggcg cgcgggcagc atgcgcgcca ggttgcggcg
     2641 gaatttcgct tccagcaggg gcttgccttc ggcgcggcgg cgcttgtggc cgacgggata
     2701 ctcgcagacg acctcatcga gccggctgcc gtcattgaac tccacggtca gggcattagc
     2761 gatcgagcgt ttgtcggggt cgtggtagtc gcgggtgaaa gccgggtctt cgatgcacag
     2821 gatgcgcgcc cgcagcgcat cgatgcgggg gtcggcggcc gccgaatcct cgtagtcggc
     2881 ggccgtgagc cgtccgaaga gcaccggcac ggccaccatg tactggatgc agtggtcgcg
     2941 gtcggcggga ttggtgagcg gcccttgctt gtcgatgatg cgcaggcagg cctcgtgcgt
     3001 gcgtatcgtg atacgccgga tatcctgggc cgagcggccc gtggccttga gctgttggtg
     3061 gatctgcatg gcacattcca ccgcggtctg ggcgtggaac tcggccgggt acgagatctt
     3121 gaacaggacg ttttccatca cgtagctgcc atagggccgc tggaagcgga agggctggcc
     3181 cttgaacagc acgtcgtaaa agccccaggt cttggccgtc agcacggtgg ggtagcccat
     3241 ttcgcccgtt ctggcgatga gtgccagccg gacgccgcgg ctggtggcgt cgcccgccgc
     3301 ccagctcttg cggctgcctg tgttgggggc gtggcggtag gtccgcaggc tctgtccatc
     3361 cacccacgcc agggagacgg cattgatgat ttcatcgcgc gacaggccca gcatccgcgc
     3421 caccacggcc gtggtggcga ccttgaccag cacgacgtga tccagcccta ctttgttgaa
     3481 ggcgttttcc agcgccaggc aaccctggat ttcgtgcgcc ttgatcatgg cggtaagcac
     3541 gtcacgcatg gtcagggccg gcttgccggc cgccacggcg ctgcgcgaga gccaatcggc
     3601 ggtggccagg atcccgccca gattgtccga cggatggccc cattcggctg ccagccaggt
     3661 gtcgttgaaa tccagccagc ggatcatggc gccgatattg aaggccgcct ggacgggatc
     3721 gagctggaac gaggtgccgg gcaccttggc gccgttgggc acgaccgtgc ccggcacgat
     3781 ggggccaagc agctttttgc aggcggggta ttcgagcgcc tcgaggccgc agcccagggt
     3841 gtcgatcagg cagttgcggg ccgtttcgaa ggccagcggg ctttggatgt catcgccgat
     3901 gacatagtcg gcgatgtcgg ccaggacctg gtccgggcgg gccgagggag gggaagcgga
     3961 catagaagcg taacccccta tgcatgggcg gggccggatg gccccgccgg atcaaggact
     4021 tacttgcgct tttcgagcgg gacgaacttc aggttctccg gaccggtgta gttggcggtg
     4081 ggccggatga tcttgttgtc gatgcgctgc tcgatgatgt gggccgacca gcccgccgtg
     4141 cgcgcgatca cgaacagcgg cgtgaacatg gcggtgggca cgcccatcat gtgatagctc
     4201 acagccgaga accagtcaag gttggggaac atcttcttga tgtcccacat gacggtctcc
     4261 aggcgctcgg cgatgtcgaa catcttggtg ctgcccgctt tcttggacag cttgcgggcg
     4321 acttccttga tgaccttgtt gcgcgggtcg gaaatggtgt agaccgggtg gccaaagccg
     4381 atgatcactt ccttgttctc gacgcggcgg cggatgtcgg cctcggcttc gtcgggcgag
     4441 tcgtagcgct tctggacttc gaaggccact tcgttggcgc cgccgtgctt ggggccgcgc
     4501 agcgcgccga tggcgccggt gatggccgaa tacatgtcgg aacccgtgcc ggcgatcacg
     4561 cggccggtga aggtcgaggc attgaactcg tgctcggcgt acaggatgag cgaggtgtgc
     4621 atggcgcgca cccagtcatc gctgggtttc tggccatgca gcaggtgcag gaagtggccg
     4681 ccgatgctgt cgtcatcggt ctgcacatcg atgatgcggc cgttgtggct gtagtggtac
     4741 cagtagagca gggccgagcc cagattggcc atcaggcggt cggcgatatc gcgcgcaccc
     4801 ggggtgttgt ggtcatcctt ctcgggcagc acgcagccca gcacggatac ggcggtgcgc
     4861 atcacgtcca tggggtggct ggccgcgggc agcgactcca gcgcggtctg cagctgcgcc
     4921 ggcagcccgc gcagcgaacg cagcttctct ttgtaggcct tcagttcggc cttgttgggc
     4981 agtttgccgt gcaccagcag gtgagcgatc tcttcgaact cggctgcgtc ggcgaaatcc
     5041 aggatgtcat agccgcggta gtgcaggtcg ttgcccgtgc ggcccacggt acacagcgcg
     5101 gtgttgcccg cgaccacgcc cgacagggcc accgatttct tgggcttgaa gccggccttt
     5161 tcttcggttt gcgccggggc gggcgcagcc tttttctgcg aggtgctcat gtctctcgtt
     5221 ctccttccga tgggaataga cacagacgga gccggcccgg ccggatggac gggccagcgc
     5281 gcattacttc gacttgtcct tggcaaacag cgaatccagc tgcgactcga aggcgtggta
     5341 tccgatacgg tcgtagagtt cgtcgcgggt ctgcatcagg tccagcacat tcttctggtg
     5401 gccgtcgcgg cggatggctt catagacggc ttcggcggcc ttgttcatcg cgcggaaggc
     5461 cgacagcgga tagaggacca tgcccacgcc ggcgctcttg agttcctcga ccgtgaacag
     5521 cggcgtcttg ccgaattcgg tgatgttggc gaggaccggt actttcacgg cgtcgacgaa
     5581 gcggcggtag gtggccaggt cgtaggcggc ctcggcgaag atggcatcgg caccagcctc
     5641 gacgcaggcc agggcgcgct cgatggcggc gtccacgcca tgcgaggcga tggcgtccgt
     5701 gcgcgcgatc aggtagaagt cgctgtcggt gcgcgcatcg gcggccgcct tgacgcggtc
     5761 ggccatctcc tcggtgctga cgatttcctt gcccgggcgg tggccgcagc gcttggcgcc
     5821 gacctggtcc tcgatatggc aggcggccgc gccgaacttg atcaggctct tgaccgtgcg
     5881 gccgatattg aaggccgagg ggccgaagcc ggtgtcgatg tccaccagca ggggcaggtc
     5941 gcagacgtcc gtgatgcggc gcacatcggt gagcacgtca tcaagggtgt tgatgccgag
     6001 gtcgggcagg cccagggagc ccgccgccac gccgccgccg gaaagataga tcgcgcggta
     6061 gccggcgcgc ttggccagca gggcgtgatt ggcgttgatg gcgccgatga tctgcagcgg
     6121 ctgctcttgg gccagcgcgc ggcgaaagag ggcgccggga gagtcgggtc tggacatgtt
     6181 tggggtctcc gagtgatgtt gtggcctgcc tcgcggggcc aggcggcttc tttttgtgca
     6241 agggggcggc tttggccaca ccctagcggc gtccggaaaa taactctgtc cccttggcga
     6301 caatcgaaag agacacactg atgctccggc acaggctcct ggaaattggg cccgcgcaag
     6361 cgggcccaat ccggaacagg ctgaattact tcagcaggtc tttgatgccg tcacgctctt
     6421 cgagcagttc cttcagcgtg aagtccatgc gctcgcggga gaaggcgtcg acttccagat
     6481 ccttgatcat ggtgtattcg ccgttggccg tggtgacggg gaaaccatag atgatgcctt
     6541 cggggatgcc gtaggagccg tccgagggga tgcccatggt gacccacttg ccattgctgc
     6601 ccaggaccca gtcgcggacg tggtcgatgg cggcgttggc ggccgacgcg gccgaggaca
     6661 ggccacgggc ttcgatgatg gcggcgccgc gcttgcccac ggtggggatg aacacgtcgc
     6721 ggttccaggt ttcgtcgttg atcagcttgg ccagcggctg gccgtcaacg gtggcgaagc
     6781 gatagtccgg gtacatcgtg ggcgagtggt tgccccagac gaccagtttc tcgatgccgg
     6841 ccacggcctt gccggacttg gcggccagtt gcgacagggc gcggttgtgg tccaggcgca
     6901 gcatggcggt gaagttcttg gcgggcaggt ccggcgccga cttcatggcg atgtaggcgt
     6961 tggtgttggc cgggttgccg accaccagca ccttgacgtt gcggctggcc acttcgttca
     7021 gggcgcggcc ctgggcggtg aagatctggg cgttgacggt cagcaggtcc ttgcgctcca
     7081 tgccggggcc gcgcggacgg gcgccgacca gcagggccac gtcggcgtcc ttgaaggcgg
     7141 tcttcggatc gctgtgggcg gtgacttcct gcagcagcgg gaaggcgcag tcttcgagct
     7201 ccatgatcac gcccttgagc gccttctggg ccttctcgtc ggggatttcg agcagttgca
     7261 ggatgaccgg ctggtccttg ccgagcattt cgccggaggc gatgcggaac agcagggcgt
     7321 aaccaatttg gccggcggcg ccggtgacgg cgactcgcat ggcgggctta gacatgtatg
     7381 ttctccaaat atggacgggc gagatgaatc gcgccagaca gtgtaatcct tggagcccgc
     7441 cgaactcggt ctggcacggc gctccgacag cccgaaatcc tagatcgaat ttacccctgc
     7501 gtcaatttat cttatatctt atataagaca taagacgttg gacataatgg gcgggcttgt
     7561 gccacaataa tgcgtttgcc cgacaccggg ccagcccgca ttcgcgctgt cggcctccaa
     7621 gcaggcaggt cctagcgtaa cgcttcgggt ccgtccccgg caggccgggc aaatatgaag
     7681 aattcaagac gatccatggc agatccccgg cccgactctc cgctacgtac ccgcactgcc
     7741 cggcaggcgg gcgagggcgc ggctttcagt ccgctgtatc gccagatcaa ggatctgctg
     7801 gtccagagcc tcgagcgagg cgaatggaaa cccggcgaac tcatcccctc cgaaatcgat
     7861 ctcgccgccc gcttccaggt aagccagggc acggtgcgca aggctgtcga cgaattggcc
     7921 gccgagcaca tgctgctgcg ccgccagggc aagggcacct tcgtggccac gcatcacgag
     7981 gcccgtgtgc gctaccgctt tctgcgcctg gcgcccgacg aggccggcga gggcgggcgg
     8041 gccgaaaacc acgtcctgga atgccggcgg atcagagctc cggccgagat cgcccgcgcc
     8101 ctggagctgc gggccggcga aaccgtggtt tccatccggc ggcagctggc catgaaccac
     8161 gcgccggtca tcatcgacga tatctgggtg cccggcgcgg cgttccgcgg cctgacgctg
     8221 gacctgctca aggccaaccg ggtgccgctc tacggcttgt tcgaatccga gttcggcgtc
     8281 agcatggtcc gtgccgacga aaaaatccgt gccgtggcgg cctccgaaga ggttgccgcg
     8341 ttgctgcacg ttacgccggg tacaccgctt ctgcaggtgg accgcatttc gtacacctat
     8401 ggcgacaggc ccatggaagt gcgccgcggg ctgtacctta ccgatcacta tcactaccgc
     8461 aatagtttga attgatgagc tttttcccta cgatttgata cgaacccgct ctctgagcga
     8521 aaatagcttg tttgcccatt tgggcaatgg cgtttccgcc gtcacgattc cctagttccg
     8581 aaacaccgag gccgtcatgt ccgactcagc tgccaagccg cgtccacagt ttcgcaatat
     8641 cagcgttccg caaatcctca gttaccgcct gcccctggcc ggcaaactgt ccatcctgca
     8701 tcgcgtcagc ggcgccttgc tctttctctg tctgcccttg gtcatcgtgc cgctgttcgc
     8761 ggctagcgtg acctcgccgg aaagctttgc gcaagtggcc caatatgcgg ccaatcccct
     8821 ggtcaagctc gtgctcctgg tgttgatctg gggctatctg catcacttct gtgccggcat
     8881 ccgctacctg gtccttgatc tgcacatcgg catcgacaag gcttcgagcc gcaagagcgc
     8941 cgcggccgtg ttcgcggtca gcctggtcct gaccctggtg ttcgctctca aattgttcgg
     9001 agtcctgtaa tgcaagacac caagaacttc ggccccaagc gcctcgtcgt cggcgcgcac
     9061 tacggcacgg tggatttcat cgcccagcgc ctgacggcca tcatcatggc cgtctacacc
     9121 ctggtgctga tcatcggcct gctggtcatg ccggcctaca cctatgaaaa ctggaaggcc
     9181 ctgttcacct tccatgtgtt cgctcttccc ctgggccaga tcctggcctc gctcgctttc
     9241 tttgcgctgg cctggcatgc ctggatcggc gtgcgcgaca tctggatgga ttatgtacgg
     9301 ccggtgggtg ttcgcctgct gctgcaagtg ctgaccatcc tctggctcgt tggcacggtc
     9361 gtgtacttcg cgcaaatcat ctggagaatc taagccgtgg tcgctgtcat gaattcattg
     9421 ccgcgccgcc aatttgacgt ggtggtcgtg ggcgccggcg gagccggcat gcgctgttcg
     9481 ctgcaactgt cccaggcggg actgtcggtg gcggtcctgt ccaaagtgtt ccccacgcgc
     9541 tcgcacaccg ttgccgcgca gggcggcgtg agcgcctcgc tgggcaacat gagcgaagac
     9601 aactggtact ggcacatgta tgacaccgtc aaggggtcgg actggctggg cgaccaggat
     9661 gccatcgagt tcatgtgccg cgaagcgccc aatgccgtct acgagctgga gcacttcggc
     9721 atgccgtttg accgcaatcc ggacggcacc atctaccagc gccccttcgg cggccatacc
     9781 gccaacttcg gcgagaagcc cgtgcagcgc gcctgtgccg cggccgaccg gaccggccac
     9841 gccctgctgc acacgctcta ccagcgcaac gtcgccgccc gcacgaagtt cttcgtcgag
     9901 tggatggccc tggacctgct gcgcaacgaa gagggcgatg tcgtgggcgt gaccgccctg
     9961 gaaatggaaa ccggcgacat ctacatcctc gaagccaaga ccacggtgct ggccaccggc
    10021 ggcgccggcc gcatctgggc ggcctcgacc aacgccttca tcaacaccgg tgacggcctg
    10081 ggcatggcgg cgcgcgcggg tatcccgctg caggacatgg agttctggca attccacccc
    10141 accggcgtgg ccggcgcggg cgtgctgatc acggaaggcg tgcgcggcga aggcggcatc
    10201 ctgctgaaca aggacggcga gcgcttcatg gagcgttatg cgcccaccct gaaggacctg
    10261 gcgccgcgcg acttcgtgtc gcgctcgatg gaccaggaaa tcaaggaagg ccgcggctgc
    10321 ggtccggacg gcagctatgt ggtgctcaag ctcgatcacc tcggtgccga cgtgatcaac
    10381 aagcgcctgc cgtccatccg tgaaatcgcc atcaagttcg gcaacgtcga tcccatcaag
    10441 gaaccgatcc ctgtcgtgcc gaccatccac tatcagatgg gcggcattcc ggccaactac
    10501 catggccagg tgctcgagcg cgtcaacggc gagaacaaga tcgtcaacgg tctatacgcc
    10561 atcggcgaat gcgccgcggt gtcggtgcac ggcgccaacc gcctgggcac caactcgctg
    10621 ctggacctga tcgtgttcgg ccgcgccacg ggcaaccaca tcgtcaactc gcatcccgag
    10681 cgccagcacg cccacaagcc ggtgcccaag gaagccgtcg acttctcgat ggaccgcgtc
    10741 aacaagctgg aatcgcgcac ctccggggaa aagacccagg acgtggccaa cgccatccgc
    10801 atgtcgatgc agcgtcactg cggcgtgttc cgcacgctgg acctgctcaa cgaaggcgtc
    10861 cagcagatcg aagacctggc caaggtggcc ggcagcatct acttcaagga caagtccaag
    10921 gtgttcaaca ccgcccgcgt cgaggcgctg gagctggcca acatgaccga agtggcccgc
    10981 gccaccatca agtcggccgc caaccgcacc gaaagccgtg gcgcgcacgc cctgaacgac
    11041 ttcccgaacc gcgacgacga aaactggctc aagcacacgc tctggtattc cgaaggcagc
    11101 cgcctggact acaagccggt tcagatgaag cctctgacgg tcgaatcctt cccgcccaag
    11161 gcccgtactt tctaagcagg atgccggtat gagcaccaaa cgaatcgtta aattcgaaat
    11221 ctaccgctac gatccggaca aggacgagcg tccctatatg cagaagctgg aagtcgagct
    11281 ccagccgacc gacaagatgc tgctcgatgc gctggtgcgc atcaagaacg acgtcgacga
    11341 cagcctggcc ctgcgccggt catgccgcga gggtgtctgc ggctccgacg ccatgaacat
    11401 caatggcaag aacggcctgg cctgcacgac caacctgcgc gaactgaagg aacccatcgt
    11461 cctgaagccg ctgcccggcc tgcccgtgat ccgcgacctg atcgtggaca tgacgcactt
    11521 cttcaaccag taccactcgg tcagtccctt cctgatcaac gacacgccgc cgcccgagcg
    11581 cgagcgcctg cagtcgccgg aagcgcgtga agagctggac ggcctgtacg agtgcattct
    11641 gtgcgcctgc tgctcgacct cctgcccctc gttctggtgg aatccggaca agttcgtcgg
    11701 ccccgccggc ctgctgcaag cctaccgctt catcgccgac agccgcgacg aagccaccgg
    11761 ccgccgtctg gacaacctgg aagacccgta ccgcctgttc cgctgccaca cgatcatgaa
    11821 ctgtgtcgac gtctgtccca agggactgaa cccgaccaag gcgatcggca agatcaagga
    11881 actgatggtc cggcgtacgg tctagtgctt attagtatcg aaggccttca atgagcaagc
    11941 tcacggaact gcaaagggct cggctacgct ggcgtgcgcg ccgtggcttg ctcgagaatg
    12001 acctcatcat cacccggtac ctggatgcca atgaactcca gcttaccgac gaagacgtat
    12061 cggcgctgac gcagctcttc gagcttggag ataatgatct gctcgatctg ctgctggcgc
    12121 gcaaggagcc ggagggggca ttggacaccc cgaggctgcg cgccatcatt gcccagatgc
    12181 gagagctctg attcattacg aggaaacagc gatgaacctg tctgacaaaa aagccactct
    12241 atccctatcg gatggcagcg cacctatcga actcccggtg tacaagggca ccctcggccc
    12301 ggatgtcatc gacatccgca agctgtatgg ccagacgggc atgttcacct atgaccccgg
    12361 cttcatgtcg accgccgcga cttcctcggg catcacttat atcgacggcg acaagggcga
    12421 gctgctgtat cgcggctatc cgatcgaaca gctggccgtc aactgcgact tcctcgacat
    12481 ctgctacctg atcctgaacg gcgacctgcc caacggtgaa cagaagaccg acttcgactc
    12541 gcaagtgacc catcacacga tggtcaacga gcagctgcat ttcttcctgc gcggcttccg
    12601 ccgcgatgcc cacccgatgg ccgtgctgac cggcctggtg ggcgcgctgt cggccttcta
    12661 tcacgattcc accgacatca ccaacgccca gcatcgccac atctccgcga tccgcctgat
    12721 cgccaagatg ccgacgctgg tcgccatggc gtacaagtat tcgcaaggcc agcccttcat
    12781 ctatccgcag aacgacctgt cgtacaccgg caacttcctg cgcatgatgt tcgccacgcc
    12841 gtgcgaagaa tacaaggtca acgaagtggt cgagcgcgcg ctggaccgca tcttcatcct
    12901 gcacgccgat cacgagcaga acgcctcgac ctcgaccgtg cgcctgtgcg gctcctcggg
    12961 caccaacccc tttgccgcca tcgccgccgg cgtggcgtgc ctgtggggtc cggcccatgg
    13021 cggcgccaac gaagcctgcc tgcagatgct cgaagaactg caagccaacg gcggcgtggc
    13081 caaggtcggc gagttcatgg aaaaggtcaa ggacaagaac tcgggcgtgc gcctgatggg
    13141 ctttggccac cgcgtctaca agaactacga cccgcgggcc aagctgatgc aggaaacctg
    13201 caaggaagtg ctgggtgccc tgggcctgga aaacgacccg ctgttcaagc tggccatgga
    13261 gctggagcgc atcgctctcg aggacgacta tttcgtgcag cgtaagctct accccaacgt
    13321 ggacttctac tcgggcatcg tgcagcgcgc catcggcatc ccgacctcgc tgttcacggc
    13381 catcttcgcg ctggcccgca cggtgggctg gatcgcccag tggaacgaaa tgctgtccga
    13441 tcccgattac aagatcggcc gtccgcgcca gctctacacc ggctcagtcg tgcgcaacgt
    13501 cccgaagcgc tgatcgcagt ccccggccgc ctgccgcagg cggccggcgc ggtgcccggc
    13561 ccaggccggg cttttttttt gggcaggcgg tccgggcggc ggcgtcccgc ctaggtttgc
    13621 ggcgccagct ccaggaagcg tgcgatcagc tgcacgggct ggcgctcgcg caggcaatag
    13681 agatactcat gcatcatgat gcgcgtgccc gagagctcca gcgcggccag ttgaggatgg
    13741 gcgggcgcct cgcgggccgg tatcaggctc agacccagat tgcacaacac ggcctggcgg
    13801 atggattcgc ggctgccgat ttcgagtatc gtggcgggcg tcacgccggc ctcggccagg
    13861 gcctgctcgg tcaattgccg ggtcatggag ccgggctcgc gcagcagcag ggtatagggc
    13921 cgcagatcgg ccagcgagac cgaggcgcgg tcggccagcg gatgttcgcg gtgcaccacc
    13981 acgcgcaagg ggtcggcggc gatcgtgcgc cggtagagat gcttgtcctc cgtggcgtag
    14041 gaggaggtcg cgatctcgat gcgatattcg tgcagggcct gcagcatgct ttgcgaattg
    14101 cctatggtca gctgcagttc tatgccaggg tagcgctcgt tgtagcgcct gaccgtgtcc
    14161 atgatgtaga aggggccggt ggcgccgatg cgcagattgc cttcgcgcag ttcgcaagca
    14221 tcgcgcaggc ggaattcaat ctcgctttcc tggagcatca gctgttcgac cagcggcatg
    14281 agccggtggc cggcatccga caggcgcaat gagcggccct ggcgataaaa gagttcgata
    14341 ccgtagcggg attcaagctg gcgtaattgg cctgtcacgg tgggctggct tactcccagc
    14401 tgcgcggccg ccttggtgac ggatccgcag cgggcgacgg cataaaagga tttgagttcg
    14461 gcgacgagca aaggcgatgg cacgcgcgcg gcgtgtccga agtggcggca aggtaggcca
    14521 gtagaccaaa atattttgat gatttcatta ctgcatttgc gcgaactgtc atagacagtc
    14581 catgcaagct cccgatactg gcggccaggc aagaaaccgc atcagtaggg aggggtaatg
    14641 agcctagccg acgacacatt tctgtcggtg cgcaatctcg ggaagcgcta tggcggccat
    14701 accgcgctcg cggatgtgtc gctggatata tgcgccgggg aactggtctg cctgctgggc
    14761 ccatcgggct gcggcaagac cacgttgctg cgcgccattg ccggcctgga tccccaggat
    14821 agcggcagca tcgtcctgtc cggccgtgat atctcgcgcg ccgcgccggc cgagcgcgac
    14881 tacggcatcc tgttccagtc ctatgcgctg tttcccaact tgaccgtcgc gcagaacgtc
    14941 gcctatggcc tgagcggcca gcgcgcccat cgccagcgcg tcgctgcgcg cgtggaggaa
    15001 atgctggacc tggtcgggct gagcggcgcg gccggccaat accccgggca gttgtccggc
    15061 ggccagcagc aacgtgtggc gctggcgcgc gctctggcgc cggcgccgtc gctgttgttg
    15121 ctggatgagc ccatgtcggc gctggacgcc cgggtgcgca cgcatctgcg cgccgagctg
    15181 cgcgcgctgc agcgccggct ggccatcacc acgctcatgg tgactcacga ccaggacgag
    15241 gccatggaga tggccgaccg tatcgcggtc atgaacggcg ggcgcatcga acagttcggc
    15301 acaccgcgcg aactgtatcg ccgcccggcc acggctttca tcgccgactt cgtgggcgag
    15361 gccaactggc tgggttatga gcgcatcgat gccggccatg tgcgcgtcgg ccgtcaggtg
    15421 ctggaagtga acgaagcgcc ggccgctgag cgcggacgtc tgttcttgcg gcccgaagcc
    15481 atacgcctgg ccgaatccgg cgggctgcct tcggccaata cctttcttgc cgaggtgcag
    15541 gatggggtat tcctgggcag caactatcgc ctgaccctgc gcatcgacgg gatgcccgga
    15601 caggtcttgc aggccatcgt cccgccgcag gcgggcgatg cgctgctgga tcaatacgct
    15661 gccggccggt gctgggtgga gctgccgcgt gatgcgctac gttcctacgc ttgaagcccc
    15721 ggccgcggtg tcggcgggca agccctcgcc cgaacgcctt caggtgcccg cccggcgccg
    15781 cctgcccggc tggataggcc gttgggccgc cctggccggc cagggcagct atgccctggc
    15841 gctggtgatc tgcctggcct tgcccctggc ggccatcctg gcgcgcgcgg ccatgggcga
    15901 gcagggcggc ctggccctca tgcgcgacat cgtgctgcag agcgacttcc tggccatggt
    15961 ggggcgcagc ctggcggtag gcttgacgac cgccgccgtg gtcgtgccct gcgcctattg
    16021 ctatgcctac ggcctgacgc gcacgctcat gcccttcaag ggcctgttgc gcatgctggc
    16081 gctcttgccg ctgctggcgc cttcgctgct gccgggcatc gcgctcatct atctattggg
    16141 caaccaaggc ctgctcaaga cctggacggg cggcgccacc atctatggtt tctggggcat
    16201 cgtggccggc gaggtgtttt acacctttcc gcatgcgctg atgatcctgg tcacgggact
    16261 gacgctggcc gacggccgtc tgtatgacgc ggcgcgcgcc atgggggcgg gacccttgcg
    16321 cacctttctg acggtgacct tgcccggcac gcgctacgcc gtgttttcgg catgctgcct
    16381 ggtcttcacc ctggcggtga cggacttcgg cgtgcccaag gtggtggggg gcgattacaa
    16441 cgtgctggcc gtggaggcct acaaggccgt agtcggccaa cagaacttct ccaaaggcgc
    16501 ggccatcggc ctgatgctgc tgatcccggc ggtgctcacc ttcttgctgg accgccgcct
    16561 gcgcacccgc cagggcgccg gcctgacggg ccggtcgcag cgctatgcgc ccggccggca
    16621 cggcgcgcgc gacctgtcct tcctgctggc cggcggatgc atcgcgctga tgctggcggc
    16681 gctggtgggc gtggcggtct gggcctcctt catcaggatg tggccctaca acctgtcgct
    16741 gtcgctgcgc tcctatgact tcgacaatat ggatggcggc ggttggctgg cctggcgcaa
    16801 cagcctcacg ctggcggcgt tgaccgccgt catcggcact gccctggttt tcggcggcgc
    16861 ctggatgata gagaaactgc cggcgcgcgg cgtggcccgc ccgctgcgcg gcctggtcag
    16921 cctgctggcg ctcacgccga tggccgtgcc cgggctggtg ctgggcctgg gctacatctt
    16981 ctttttcaac agtccgctca atccgctggg cggcctgtac ggcaccatgg ccctgctggt
    17041 catctgtacg gtggtgcatt tctacaccag tgcgcacctg acagccgtga ccgcgctggg
    17101 cgcgctggac ccggagttcg aggcggcctc ggcggcgctg aaggtgcccg cgctgctgac
    17161 cttctggcgc gtgacgctgc ccatgtgcct gcctgccgtg ctcgccacgg cgcgctacct
    17221 cttcgtgtcg gccatgacca ccgtctcggc cgtggtcttt ctctacagcc cttcaacggt
    17281 cctggcggcc gtggctgtgc tcaatatgga cgacgccggc ttcatcggcc cggcggccgc
    17341 catgtgcacc gtgatcatgg ccagttccgc cgtggtgtcg ctgctgctgc atggcgccag
    17401 ccgcgcgctg ctgcgacgca cgcaggattg gcgcatggcc ccgcgcgatt gaactccttt
    17461 tttgcttacc ttggatatgc catgaacgct cttcctactc gtcttgaggc ggtcatcttc
    17521 gactgggccg gaacgctggt cgacttcggc tcttttgctc ccacgcgggt gtttgtcgag
    17581 gccttcgcgc agtttggcgt ctcgctcagc ctggagcagg cgcgcggccc catgggcctg
    17641 ggcaagtggg accacatccg tgccctatgc aacgagccgg acatcgcgca acagtatcgg
    17701 cagcgcttcg gcgtgctgcc cgacgacgcc gcggtcaccg ccatctacga gcgtttcctg
    17761 ccgatgcagc gggagaaggt cgcccagtac tcggatgtga tccctggcgc gccggatgtc
    17821 ttgcgcgagc tgcgcgcacg cggcctgaag atcggatcct gctcgggcta tccggcgtcg
    17881 gtgatggacc gggtgctgga gcgcgcccgt gccggcggca tcgagatcga aacggtcgtg
    17941 gccagcgacg aggtgccgcg cgcgcgtccc gcacccggca tggcgctcaa gagcgccgtc
    18001 gccctgggca tcgatgatgt ggccggctgc gtcaaagtcg atgacaccgg cgtaggtgtc
    18061 gaggagggcc ggcgcgccgg aatgtggtcg gtggggctgc tgctgtcggg caacgccgcc
    18121 ggcctcggcc tggatgccta ccggtcgctg gacgaggcgg gccgcgccgc ggcccgcgag
    18181 cgcgcgcgcc aggccttcgc cgccgccgaa ccgcactatt tcatcgatac cgtggccggg
    18241 ctgcccggcg tgctgagcga tatctcggcc cgcctggcgc gcggcgaacg gccctgagtt
    18301 tcccctgccc tctaccggag ttgaaccatg cctgaatttc acctgctcgc gcgccgcgcc
    18361 gtcggcctgc tggccctggc cgccgcgccc gtgatggcgc agcagaccac gctgaccgtc
    18421 tacaccgccc tcgaagccga ccagatcaag gcctaccagg ccgccttcga gcgcgagtat
    18481 cccgacatca agatccagtg ggtgcgcgac tccaccggca tcatcaccgc caagttgctg
    18541 gccgagaaga acaatcccaa ggccgacgta atctgggggt tggccggcac ctcgctgggc
    18601 ctgatggaca aggaagggat gctggaaccc tatgcgccca aaggcctgga tcagatctcg
    18661 ccgcagatgc gcgatgccaa gcccgtgccc gcctgggtgg gcatggacgc cttcgccgcg
    18721 gcgatctgct tcaataccgt ggaggccaag aagcagaatc tgccggagcc caagtcctgg
    18781 caggacctca cccgtcccga gtatgccggc aagatcgtga tgcccaatcc cgcctcttcg
    18841 ggcacgggct ttctggacgt cagcgcctgg ctgcagatct tcggcgaaga caagggctgg
    18901 gcgttcatgg acgctttgca caagaacatc ggcagctaca cgcattcggg ttccaagcct
    18961 tgcaacctgg cggcttcggg cgagttcccc atcggcgtgt cctttgatta ccgcgccgcc
    19021 aagctcaagg ccgacggcgc tccggtccag cccatctttc cctccgaggg gctgggctgg
    19081 gaagtggagg ctaccgccat cgtgcgcggc accaagaatg ccgacgcggc gcgcaaggtg
    19141 gcggatttct cggccagccg cgccgccaat gaactgtaca aggccaattt cgccgtgctg
    19201 gccattcctt cggtagcgac ctccaatccc aatctgccga ccgacctggc ttcgcgcatg
    19261 atcaagaacg atttcgtgtg ggccgccacg cagcgcgacc gcatcatcgc cgagtggacc
    19321 aagcgctacg acagcaagtc cgagccgaag aagaagtaag tcagccgtgg cgggcgcggc
    19381 cggggacgcg cccgcccatg tcgatacggg atattgcaat gagagatttt gatgccgtcg
    19441 tcgtcggcgg cggaatgctg gggatggccc atgcctgggc ttgcgcccgc cgcggcctgt
    19501 ccgtggcggt ggtcgaacgc gcccgccagg cacatggcgc caccatccgc aacttcggcc
    19561 aggtcctggt gaccggccag gcgcccggcg aaatggccgg cctggcgcgc cagacacgcg
    19621 ccttgtggct gcagctcgcc gggcaggcgg gttttcatgt gcgggccaac ggctgcctgg
    19681 tgctggcccg caacgcgcac gagcgcgacg tgctggaaga gttcgccagc gagcgcctgc
    19741 agactgaagg ctatgcggcc cagttgctca gtggccgcga actcggcgcc ttctatggcg
    19801 gccgcctgga tcatcattgc gcggccctgc gcggcagcga cgatctgcag atctattcgc
    19861 gcgaggcctt gcccgccatc acgcgccacc tggccgaaga catgggcgtg cgggtcatcc
    19921 atggcacgct ggcgcgccgc gccgagggcg gcgaggtcca taccaccgcg gggaatctgc
    19981 gcgcgcgcca tgttttcgtc tgcccgggac acgattacct gacactatgg ccggaactgt
    20041 tcgcccccct ggacctggag gtctcgcgcc tgcagatgct gcgcgcggcg tttgccggac
    20101 aggctttcag cctcgacatg ccgctattga cggggctgtc ctgcgtgcac tatggcgcgt
    20161 tttcggacct gcccagcgcg caacgcctgc gagcgctctt cgaggcgcgc agccccttcc
    20221 tgatgcgcga gggcattcat ctgcttatca gccccacgcc ttatggcgaa ttgatcgtgg
    20281 gcgattcgca tcgctacggc gcggacgcgc cgcccttcaa tgacgaggcg atcgacgatg
    20341 cgctcctggc gctggcccag caggcgctgg gcgcccgcct gcgggtgttg gagcgctggc
    20401 agggcgtcta tggcgcccat ggcccggcgc cttactccgt catgcgggcc gatgcgcaga
    20461 ccacggtggc ggtcatgcat tcaggcgtgg gcatgacggt aggcttggcc atcggcgagc
    20521 gggcagtggc ggatgtgctg ggctgagcgc gcccggggcg cggcaatcag aaggcgaggg
    20581 ccaggctcgc cagcaagccc gcgcccatgg cacccagaat cagcccgcag gcacgctcca
    20641 gccagggcag catccggccg aagcggcgca gcacccgcgg ccggctgatc aggaccgcca
    20701 ccagcaggtc ccagcccagc accacgccaa acatccacag gccgtaggca gcctggcggc
    20761 ccggcgaaag gccgggcgcc aggagcgtgg ccaggctggc atagaagagc gcgttcttgg
    20821 ggttcaacac gcccgagaac aagcccatgc cgagcgcgcg ccaccacgag cccgcggcct
    20881 tgccctggcc gtccagcggc gtgcgtccgg cgtggcgcag gaaaagcagg ccgaggtaga
    20941 ccagataggc gccgccggcg gcctgcaggc cccgcaacag caagccgccg tcgcgcaggc
    21001 tggatacgcc cccgaacgcc agcacgatga acagcccatt ggccagggcg atgcccaggc
    21061 aggcgccgct ggccgtgcgc cagccggcgg ccagcgcgct gcgcgccacc aggaagaaat
    21121 cgggacccgg cgagagcaag gccaggaaat gggcagaggc aatgagcagg aaggaaggca
    21181 t
//
