LOCUS       c00049_NZ_AUJE..       10592 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AUJE01000053.1 Selenomonas ruminantium subsp. ruminantium ATCC
            12561 G598DRAFT_scaffold00049.49_C, whole genome shotgun sequence.
ACCESSION   NZ_AUJE01000053
VERSION     NZ_AUJE01000053
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:54:11
            Original ID  :: NZ_AUJE01000053.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10592
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..651
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="PVEPTPTTPETPTPVEPTPTTPDTPTPVEPTPTTPETPTPVEPTP
                     TTPETPTPVEPTPTTPETPTPVEPTPTTPETPTPVEPTPTTPETPTPVEPTPTTPERPT
                     PAEQPAAAPTPAEQVQEDLGKAGVSIREMEEVTNSSRPNVQSDATSRQENRVQNDMERT
                     ENGYREAGNTENGGVTTDFGGNGMMRIENQGINPPNSMKSEDVAEQQEKKNKK"
     protocluster    1..10592
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4173:5592](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4174..5592
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10592
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10592
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             855..2135
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MKRRTFIAGGLGALGLLAGGIFWAKGTLYRKAANSMRQLTGDLDA
                     QFLRQVITTDSAHSRMLMWQAESPLVNPGIEYRIKGQEDARIVAAKQDFFTDDGVENNQ
                     YTAELTDLTADTEYEYRVAAEGAAGAWHSLHTAGEGDFQCLIFPDSQSSDYSDWEQLAQ
                     NAAQRNPQAAFFINMGDIVDNGEDHTQWQAWFHGVNGIIDRIPFVPLMGNHETYNLNWK
                     VRLPEAYLKYFAVPDNGSANFGRYYYSYDYGDVHFIVLNSQWDETEEFKPGLRDEQVAW
                     LRQDAAASRKKWKIVLVHKDVLQYRIHNRPERKEGISDVGEVFMPLFDELDIDLVFSAH
                     LHTYRNRGHIQNFQRSAKGPLYILTGVAGNVRYPGLWIDHKLDEVVAPQPETDNYLTMD
                     VKGDEITVRCFLPDGKEIDSAVVQKNH"
     PFAM_domain     1008..1259
                     /aSDomain="Pur_ac_phosph_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16656.7"
                     /description="Purple acid Phosphatase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_2_0001"
                     /evalue="1.80E-10"
                     /label="ctg49_2"
                     /locus_tag="ctg49_2"
                     /protein_end="135"
                     /protein_start="51"
                     /score="41.4"
                     /tool="antismash"
                     /translation="ITTDSAHSRMLMWQAESPLVNPGIEYRIKGQEDARIVAAKQDFFT
                     DDGVENNQYTAELTDLTADTEYEYRVAAEGAAGAWHSLH"
     PFAM_domain     1281..1886
                     /aSDomain="Metallophos"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00149.30"
                     /description="Calcineurin-like phosphoesterase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_2_0002"
                     /evalue="4.70E-17"
                     /label="ctg49_2"
                     /locus_tag="ctg49_2"
                     /protein_end="344"
                     /protein_start="142"
                     /score="63.3"
                     /tool="antismash"
                     /translation="QCLIFPDSQSSDYSDWEQLAQNAAQRNPQAAFFINMGDIVDNGED
                     HTQWQAWFHGVNGIIDRIPFVPLMGNHETYNLNWKVRLPEAYLKYFAVPDNGSANFGRY
                     YYSYDYGDVHFIVLNSQWDETEEFKPGLRDEQVAWLRQDAAASRKKWKIVLVHKDVLQY
                     RIHNRPERKEGISDVGEVFMPLFDELDIDLVFSAHLHTY"
     PFAM_domain     2368..2550
                     /aSDomain="IF3_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05198.18"
                     /description="Translation initiation factor IF-3,
                     N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_3_0003"
                     /evalue="1.30E-28"
                     /label="ctg49_3"
                     /locus_tag="ctg49_3"
                     /protein_end="61"
                     /protein_start="0"
                     /score="99.2"
                     /tool="antismash"
                     /translation="VRVTSAEGEQLGIMATRDALRLAEEQHLDLVEIAPKAKPPVCRIM
                     DFGKYRYEQQKREKEA"
     aSDomain        2368..2829
                     /aSDomain="TIGR00168"
                     /aSTool="tigrfam"
                     /description="infC: translation initiation factor IF-3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg49_3_0001"
                     /evalue="9.20E-65"
                     /identifier="TIGR00168"
                     /label="ctg49_3"
                     /locus_tag="ctg49_3"
                     /protein_end="154"
                     /protein_start="0"
                     /score="215.3"
                     /tool="antismash"
                     /translation="VRVTSAEGEQLGIMATRDALRLAEEQHLDLVEIAPKAKPPVCRIM
                     DFGKYRYEQQKREKEAKKKQKVINIKEVKLRPNIEQHDFDVKLKNALRFVEEGNKVKVT
                     IMFRGRELSHPELGKTVLGRVAEALGDRVSIERNAKLEGKNMTMIVAPKV"
     CDS             2368..2871
                     /locus_tag="ctg49_3"
                     /transl_table=11
                     /translation="VRVTSAEGEQLGIMATRDALRLAEEQHLDLVEIAPKAKPPVCRIM
                     DFGKYRYEQQKREKEAKKKQKVINIKEVKLRPNIEQHDFDVKLKNALRFVEEGNKVKVT
                     IMFRGRELSHPELGKTVLGRVAEALGDRVSIERNAKLEGKNMTMIVAPKVQKASKPKQP
                     AQES"
     PFAM_domain     2569..2826
                     /aSDomain="IF3_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00707.24"
                     /description="Translation initiation factor IF-3,
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_3_0004"
                     /evalue="1.50E-35"
                     /label="ctg49_3"
                     /locus_tag="ctg49_3"
                     /protein_end="153"
                     /protein_start="67"
                     /score="121.1"
                     /tool="antismash"
                     /translation="INIKEVKLRPNIEQHDFDVKLKNALRFVEEGNKVKVTIMFRGREL
                     SHPELGKTVLGRVAEALGDRVSIERNAKLEGKNMTMIVAPK"
     CDS             2903..3103
                     /locus_tag="ctg49_4"
                     /transl_table=11
                     /translation="MPKIKTRRAAAKRFTMTGSGENFKRNKAFKSHILEKKSPKRKRNL
                     RKAAMVTAADFGRVKRMLPYA"
     PFAM_domain     2906..3091
                     /aSDomain="Ribosomal_L35p"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01632.21"
                     /description="Ribosomal protein L35"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_4_0005"
                     /evalue="3.60E-25"
                     /label="ctg49_4"
                     /locus_tag="ctg49_4"
                     /protein_end="63"
                     /protein_start="1"
                     /score="88.3"
                     /tool="antismash"
                     /translation="PKIKTRRAAAKRFTMTGSGENFKRNKAFKSHILEKKSPKRKRNLR
                     KAAMVTAADFGRVKRML"
     aSDomain        2906..3097
                     /aSDomain="TIGR00001"
                     /aSTool="tigrfam"
                     /description="rpmI_bact: ribosomal protein bL35"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg49_4_0002"
                     /evalue="1.20E-26"
                     /identifier="TIGR00001"
                     /label="ctg49_4"
                     /locus_tag="ctg49_4"
                     /protein_end="65"
                     /protein_start="1"
                     /score="90.8"
                     /tool="antismash"
                     /translation="PKIKTRRAAAKRFTMTGSGENFKRNKAFKSHILEKKSPKRKRNLR
                     KAAMVTAADFGRVKRMLPY"
     aSDomain        3153..3494
                     /aSDomain="TIGR01032"
                     /aSTool="tigrfam"
                     /description="rplT_bact: ribosomal protein bL20"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg49_5_0003"
                     /evalue="7.90E-46"
                     /identifier="TIGR01032"
                     /label="ctg49_5"
                     /locus_tag="ctg49_5"
                     /protein_end="114"
                     /protein_start="0"
                     /score="153.0"
                     /tool="antismash"
                     /translation="MPRVKVGVTAHRRHKKILKLAKGYKGSKSKQFKKANETVMKALYY
                     ARRDRRAKKGNFRRLWIARINAAARVNGISYSRLVCGLTKAGVEVNRKMLADLAISDEK
                     AFAQLVAVAK"
     CDS             3153..3506
                     /locus_tag="ctg49_5"
                     /transl_table=11
                     /translation="MPRVKVGVTAHRRHKKILKLAKGYKGSKSKQFKKANETVMKALYY
                     ARRDRRAKKGNFRRLWIARINAAARVNGISYSRLVCGLTKAGVEVNRKMLADLAISDEK
                     AFAQLVAVAKENL"
     PFAM_domain     3159..3479
                     /aSDomain="Ribosomal_L20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00453.20"
                     /description="Ribosomal protein L20"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_5_0006"
                     /evalue="1.80E-44"
                     /label="ctg49_5"
                     /locus_tag="ctg49_5"
                     /protein_end="109"
                     /protein_start="2"
                     /score="150.3"
                     /tool="antismash"
                     /translation="RVKVGVTAHRRHKKILKLAKGYKGSKSKQFKKANETVMKALYYAR
                     RDRRAKKGNFRRLWIARINAAARVNGISYSRLVCGLTKAGVEVNRKMLADLAISDEKAF
                     AQL"
     CDS             4174..5592
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_6"
                     /sec_met_domain="TIGR03651 (E-value: 1.4e-06, bitscore:
                     18.3, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEALCIGLALLGLMYFAYRGWSIILIAPFFAGLAALASMFDILPV
                     YSELYMTRLAEYVKTYYPVFLFGAVFAKLMEKGGLASAIAGKIVDVLGEKRAILAVLMG
                     CGALTYGGLSVFVVAFVMYPFGAVVFKKADIPKRLLPAALWVGIFSFAMVSLPGTPQIQ
                     NIIPSSYFQTSTWAAPGIGLFASILFLLIGWGWIGHRAKLLQSRGEGYGEHESDGKKKR
                     HPKINIPWYWAMVPLLMVIVINVILSNPFGWEWGFHWNEDSLAAFVPLKLTLLASHVGK
                     VSAIWSISVALILSSIVAAYIGRKRLKVTDGFLPTVNYAALSSGSAALNVASGYAFGCV
                     ITAMPGFAPVTEWLVGIAASFGPLLSAVITTNIMCGITGSASGGLTIALSALGDQWAAM
                     AITAGIPLEVLHRIVAVASVGIDPVPHCGALVTLLAICGLTHNESYFDIAVIMGMKFLV
                     PFLCIIFYMLTGIC"
     CDS             complement(5649..6779)
                     /locus_tag="ctg49_7"
                     /transl_table=11
                     /translation="MGVQANGTSIAGLSKKEAHKFFTDTAAKKLQRKAAVLTYKERNFQ
                     IDPADINLHGNVDEAVETAYNIGRDGTPIENIINQMRYAIFGATVTMDASFDEQLLNSK
                     LQQIKTAIDTPPKNGSVTLLADGSIRKTPAVTGLSLEIEPLAAELAPDFKTFNLTVKKE
                     LSPAEQLPFVQDNDLASMDGILGSYTTRFYPGDRGDNIGLAASHLQGALIRSGATLSFN
                     DTVGPRTREAGYKNAGVIIYGEHAVDVGGGVCQVSSTLYNAILLAGLTPVERTGHFASS
                     SYVPAGRDATVADGLIDFVFRNPLPHPVYLTVANSGSALTVYVLGTKADLAGKSIALVT
                     EGSSMRPSLYRLWKQNGQVIEREFLHTDAYEPLKNT"
     PFAM_domain     complement(5808..6191)
                     /aSDomain="VanW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04294.15"
                     /description="VanW like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_7_0008"
                     /evalue="6.20E-44"
                     /label="ctg49_7"
                     /locus_tag="ctg49_7"
                     /protein_end="324"
                     /protein_start="196"
                     /score="148.8"
                     /tool="antismash"
                     /translation="RGDNIGLAASHLQGALIRSGATLSFNDTVGPRTREAGYKNAGVII
                     YGEHAVDVGGGVCQVSSTLYNAILLAGLTPVERTGHFASSSYVPAGRDATVADGLIDFV
                     FRNPLPHPVYLTVANSGSALTVYV"
     PFAM_domain     complement(6333..6647)
                     /aSDomain="PG_binding_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12229.10"
                     /description="Putative peptidoglycan binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_7_0007"
                     /evalue="4.40E-17"
                     /label="ctg49_7"
                     /locus_tag="ctg49_7"
                     /protein_end="149"
                     /protein_start="44"
                     /score="62.5"
                     /tool="antismash"
                     /translation="QIDPADINLHGNVDEAVETAYNIGRDGTPIENIINQMRYAIFGAT
                     VTMDASFDEQLLNSKLQQIKTAIDTPPKNGSVTLLADGSIRKTPAVTGLSLEIEPLAAE
                     L"
     CDS             7122..7403
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MIKPLGERVVIEVAEGDVKTASGIVLPDTAKEKPQKGTVVAVGTG
                     KLLENGERAAMEVKAGDTVVFSKYSGSEVKVDDKEYLIVRESDILAIL"
     PFAM_domain     7125..7397
                     /aSDomain="Cpn10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00166.23"
                     /description="Chaperonin 10 Kd subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_8_0009"
                     /evalue="2.50E-36"
                     /label="ctg49_8"
                     /locus_tag="ctg49_8"
                     /protein_end="92"
                     /protein_start="1"
                     /score="123.7"
                     /tool="antismash"
                     /translation="IKPLGERVVIEVAEGDVKTASGIVLPDTAKEKPQKGTVVAVGTGK
                     LLENGERAAMEVKAGDTVVFSKYSGSEVKVDDKEYLIVRESDILAI"
     CDS             7431..9059
                     /gene_functions="other (smcogs) SMCOG1299:chaperonin GroEL
                     (Score: 843.6; E-value: 8.1e-256)"
                     /gene_kind="other"
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MAKQILFDEEARRALGRGVDALANAVKVTLGPKGRNVVLEKKFGA
                     PTITNDGVTIARDIELEDPFENMGAQLVKEVATKTNDIAGDGTTTATLLAQAMIREGMR
                     NVVAGANPMIIKKGIDKAVAALVDEIQSKAKTIESKADIAQVATISSANEETGELIAEA
                     MEKVGKDGVITVEESKSMATNLSVVEGMQFDRGYISPYLVTDTDKMEAVLDDPYILITD
                     RKISAIADILPILEQVVKQGKQLAVIAEDVDGEALTTIVVNKLRGTFKALAVKAPGFGD
                     RRKAMLEDIAILTGGTVISEELGRKLDSVTLEDLGRARQIRSTKEETTIVDGVGDKDAI
                     AARVAQIKKQIAETTSDFDKEKLQERLAKLAGGVAVIEIGAATEVEMKDKKYRIEDALN
                     ATRAAVEEGIVAGGGTTFIDILPALDKINVEGDEKVGVNIVRRAIEEPVRQIADNAGLE
                     GSVVVEAVKKAGDGIGFNALKNEYVDMIKAGIVDPAKVTRSALQNAASIASMVLTTETL
                     VADKPEEKPAMPAGGAPGMGMPGMM"
     aSDomain        7434..9002
                     /aSDomain="TIGR02348"
                     /aSTool="tigrfam"
                     /description="GroEL: chaperonin GroL"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg49_9_0004"
                     /evalue="3.50E-256"
                     /identifier="TIGR02348"
                     /label="ctg49_9"
                     /locus_tag="ctg49_9"
                     /protein_end="524"
                     /protein_start="1"
                     /score="848.7"
                     /tool="antismash"
                     /translation="AKQILFDEEARRALGRGVDALANAVKVTLGPKGRNVVLEKKFGAP
                     TITNDGVTIARDIELEDPFENMGAQLVKEVATKTNDIAGDGTTTATLLAQAMIREGMRN
                     VVAGANPMIIKKGIDKAVAALVDEIQSKAKTIESKADIAQVATISSANEETGELIAEAM
                     EKVGKDGVITVEESKSMATNLSVVEGMQFDRGYISPYLVTDTDKMEAVLDDPYILITDR
                     KISAIADILPILEQVVKQGKQLAVIAEDVDGEALTTIVVNKLRGTFKALAVKAPGFGDR
                     RKAMLEDIAILTGGTVISEELGRKLDSVTLEDLGRARQIRSTKEETTIVDGVGDKDAIA
                     ARVAQIKKQIAETTSDFDKEKLQERLAKLAGGVAVIEIGAATEVEMKDKKYRIEDALNA
                     TRAAVEEGIVAGGGTTFIDILPALDKINVEGDEKVGVNIVRRAIEEPVRQIADNAGLEG
                     SVVVEAVKKAGDGIGFNALKNEYVDMIKAGIVDPAKVTRSALQNAASIASMVLTTETLV
                     ADKPEE"
     PFAM_domain     7494..8993
                     /aSDomain="Cpn60_TCP1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00118.26"
                     /description="TCP-1/cpn60 chaperonin family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_9_0010"
                     /evalue="3.80E-96"
                     /label="ctg49_9"
                     /locus_tag="ctg49_9"
                     /protein_end="521"
                     /protein_start="21"
                     /score="322.7"
                     /tool="antismash"
                     /translation="LANAVKVTLGPKGRNVVLEKKFGAPTITNDGVTIARDIELEDPFE
                     NMGAQLVKEVATKTNDIAGDGTTTATLLAQAMIREGMRNVVAGANPMIIKKGIDKAVAA
                     LVDEIQSKAKTIESKADIAQVATISSANEETGELIAEAMEKVGKDGVITVEESKSMATN
                     LSVVEGMQFDRGYISPYLVTDTDKMEAVLDDPYILITDRKISAIADILPILEQVVKQGK
                     QLAVIAEDVDGEALTTIVVNKLRGTFKALAVKAPGFGDRRKAMLEDIAILTGGTVISEE
                     LGRKLDSVTLEDLGRARQIRSTKEETTIVDGVGDKDAIAARVAQIKKQIAETTSDFDKE
                     KLQERLAKLAGGVAVIEIGAATEVEMKDKKYRIEDALNATRAAVEEGIVAGGGTTFIDI
                     LPALDKINVEGDEKVGVNIVRRAIEEPVRQIADNAGLEGSVVVEAVKKAGDGIGFNALK
                     NEYVDMIKAGIVDPAKVTRSALQNAASIASMVLTTETLVADK"
ORIGIN
        1 ccggtagagc cgacgccgac cacgccggaa acgccgactc cggtagagcc gacgccgacc
       61 acgccggaca cgccgacccc ggtagaaccg acgccgacca cgccggaaac gccgaccccg
      121 gtagaaccga cgccgactac gccggaaacg ccgaccccgg tagagccgac gccgaccacg
      181 ccggaaacgc cgactccggt agagccgacg ccgaccacgc cggaaacgcc gaccccggta
      241 gaaccgacgc cgaccacgcc ggaaacgccg accccggtag aaccgacgcc gaccacgccg
      301 gaaaggccga ctccggcaga acagccagca gcggctccga ctcctgcaga gcaggttcag
      361 gaagacctcg gcaaagctgg cgtcagcatt cgggagatgg aggaagtgac caattcctcc
      421 cgtcccaatg tgcaaagtga tgcaacttcc agacaggaaa accgggttca gaacgatatg
      481 gaacgtacag aaaatggcta tcgcgaagca ggtaacacag aaaatggagg cgtgacaaca
      541 gactttgggg gaaacggcat gatgcgcatt gaaaaccaag gcattaatcc gcccaactcc
      601 atgaaaagcg aagacgtggc cgaacagcag gaaaagaaaa acaaaaaata agcatagcgg
      661 atatcgtttc gtagactaaa agcaaaaaga tgagagccct tgatagaaat atcgggggct
      721 atttttatgc gcaaaaaaag aagagcctcc ggtaacataa tccgtctgac gcaatgaatg
      781 atgaaaatgt tgttcttgac ttaaagtcga ctccaagtgc taaaataaag aaaaatatgg
      841 aagtggaggc aaatatgaag cgtagaacat ttattgcggg tggtcttggt gcattgggcc
      901 tgctggccgg cggcatcttt tgggccaaag gaacattata ccgcaaggcg gccaacagta
      961 tgcggcagct gaccggtgat ttggatgcgc agtttttgcg gcaggtaatt acgacagaca
     1021 gcgcccacag ccgcatgctg atgtggcagg cggaaagccc attggttaat ccgggcatag
     1081 aatatcgtat taaagggcag gaagatgccc ggattgttgc cgcaaaacag gattttttca
     1141 ccgatgatgg tgtggagaat aatcaatata cagccgaatt gacggattta acagccgata
     1201 ccgagtatga ataccgcgtg gctgccgaag gggcagcagg ggcatggcat tctttgcata
     1261 ctgcgggaga gggggatttc caatgtctga ttttcccgga ttcccagtcc agcgattaca
     1321 gcgattggga acagctggcg caaaatgcag cacagcgtaa tccgcaggcg gcctttttca
     1381 tcaatatggg tgatattgtg gacaatgggg aagatcatac gcagtggcag gcctggtttc
     1441 acggcgtgaa cggcataatt gaccggattc ccttcgtgcc gttgatgggt aaccatgaaa
     1501 cctacaatct gaattggaag gtgcgcctgc cggaggccta tttgaagtat tttgccgttc
     1561 cggataatgg cagcgcaaac tttggccggt attattattc ctatgactat ggtgatgtac
     1621 attttatcgt gctgaacagt cagtgggacg aaacggagga attcaagccg ggcctgcggg
     1681 acgagcaggt ggcctggctg cggcaggacg ctgcggccag ccggaagaag tggaagattg
     1741 tgctggtgca taaggatgtt ttgcaatacc gcatccataa ccgtccggag cgcaaggaag
     1801 ggatatccga tgtgggcgaa gtctttatgc cgctgtttga tgaattggac atcgaccttg
     1861 tcttttcggc ccatttgcat acttaccgca accggggcca tatccagaac ttccagcgca
     1921 gcgcgaaggg gccgctgtat atccttaccg gtgtggcggg gaatgtgcgc tatcccggct
     1981 tgtggattga ccataagctc gatgaagtcg ttgcaccgca gccggaaacg gataactacc
     2041 tgaccatgga tgtaaagggc gatgaaatca ccgtccgctg cttcctgcca gacggcaagg
     2101 aaattgattc ggcggttgtg caaaaaaatc attgacaacc gtgcattcac tatgataaac
     2161 taatcaagtc gtgaacaaga agaagccacc gcttctcacc tgatggccgc atgtgaaggt
     2221 cagttgggtt tatagctttg agtttttgaa aggtggcttt gtgccgcctt tttcttgttt
     2281 ggataagaga tgtagacttt aagcaggagg tgttttacta ttagcaaaga atctttacgc
     2341 atcaatgagg aaattcgcat ccgtgaagtg cgtgtgacca gcgccgaagg cgaacagctg
     2401 ggcatcatgg caacccgtga cgcgctgcgt ctggccgaag aacagcatct tgacctcgtc
     2461 gagattgcgc cgaaggcaaa gccgccggtg tgccgcatca tggacttcgg taagtaccgc
     2521 tatgaacagc agaagcggga aaaggaagcg aagaagaagc agaaggttat taacatcaaa
     2581 gaagttaagc ttcgccccaa cattgaacaa cacgattttg acgtcaagtt gaagaacgca
     2641 cttcgtttcg tagaggaagg gaacaaggtc aaagtgacca tcatgttccg tggccgtgag
     2701 ctttcccatc cggaactggg caaaactgtc ctgggccgtg tggcagaagc cctgggcgac
     2761 cgtgtttcca ttgaacgcaa tgccaaactt gaaggaaaaa atatgacgat gattgttgca
     2821 ccgaaagtgc agaaagcatc gaagcccaaa cagcctgcac aggaatcctg agtgcaaagg
     2881 ctaatttaag gaggaaaatg taatgccaaa gattaagact cgcagagcag cagctaaacg
     2941 cttcaccatg actggtagcg gtgaaaactt caaacgcaac aaggctttca agagccatat
     3001 cctggagaag aagtctccga agcgtaaacg taacctgcgc aaagccgcta tggttactgc
     3061 cgctgatttc ggccgcgtaa agagaatgct cccgtacgca taattttttc gtaaatgact
     3121 cgtttatttt gattttttag gaggatgaaa ccatgccaag agtaaaagta ggcgtgactg
     3181 cacatagacg tcataagaaa atcctgaagc tcgctaaggg ttacaaaggt tccaagagca
     3241 aacagttcaa gaaagctaac gagaccgtaa tgaaggctct ctactacgct cgtcgtgacc
     3301 gtcgtgcgaa gaagggcaac ttccgtcgtc tctggattgc tcgtatcaac gctgctgcac
     3361 gtgtaaacgg catttcctac agccgtctcg tttgcggtct gaccaaggct ggcgttgaag
     3421 taaaccgcaa gatgctggct gacctggcca tctccgatga aaaggctttc gctcagctcg
     3481 ttgctgttgc taaagaaaac ctctaatttc aggtttatag cgaacgtgaa gacagttcct
     3541 gcgggggctg tctttttctc atgcaaaaat tatttattgc gttgacaata aagaaaattt
     3601 atgctaatat acatacagta aacgaaagca caatcgaata ttggttgggt caggtgtcat
     3661 agacttaata gggaagccgg tataagccgg cgcggtcccg ccactgtaac agcgagttta
     3721 tctgcatagt tatgtcactg gaggtttcct ctgggaaggc gcagataaat gatgaactgg
     3781 agccaggaga actgcctgat taacaatcgc cgttaagagc ctgatggctc tttggacctg
     3841 cgagtgatgg ggatggagat ttatcggtac tgaaaagttt ttagagcctg gtttagtgtg
     3901 ggtattttcg agtagcgtaa ataagctctt ccctgcgcgg gaggagctat tattttgccc
     3961 gtttcgtcga aaagtttttc ctgttagttt tctgacaggg agaaatgctc atacatttca
     4021 ttcagttcta tggattgtct gcgttcatgc agcagctccg atacgctata tcggagctta
     4081 tttttttctt tccatttaca taggggacgt tgttcccaag actatcaggg attgtggata
     4141 gtataaattc tacgagggga gtctttggac accatggaag cactttgtat tgggttagca
     4201 cttttaggac ttatgtattt tgcctaccgc ggctggtcaa tcatcctgat tgcacccttc
     4261 tttgcgggat tggcagcact ggccagtatg tttgatattc tgcctgtata cagcgaactg
     4321 tatatgacga ggctcgcgga atatgtgaag acatattatc cggtattcct gtttggtgcg
     4381 gtatttgcaa aattgatgga aaaaggtggg ctggcctcag cgattgccgg taagattgtg
     4441 gacgttttag gggaaaaacg ggcaatcctg gcggtgctca tggggtgcgg tgcattgaca
     4501 tatggcggtt tgtctgtatt tgtcgtggcc tttgttatgt atccgtttgg cgcggtagtc
     4561 tttaagaaag cggatattcc caaaagactg ctgcccgcgg ccttgtgggt aggtattttc
     4621 tcttttgcga tggtttccct tcctggaaca ccgcaaattc agaatattat tccgtcctct
     4681 tattttcaga caagtacctg ggcggctccg ggcatcggct tatttgcttc aatcttgttc
     4741 ctgctgattg gctggggctg gattggccat cgggcaaagc tcctgcagtc ccgtggagag
     4801 ggctacgggg agcatgaaag tgatggaaag aagaaacgtc atccgaaaat caacattcct
     4861 tggtattggg caatggtgcc gttgcttatg gttattgtga ttaacgtgat tctgtccaat
     4921 ccgtttggtt gggaatgggg ctttcattgg aatgaggaca gcttagcggc ttttgtgcca
     4981 ttgaagctga cgcttttagc ctcgcatgtc ggcaaggtat cggcaatttg gtccattagc
     5041 gtggcactta ttctcagcag tattgtggca gcgtatattg gccgcaaacg gctgaaggtt
     5101 acggatggtt ttctgccgac ggtcaactat gcggcgcttt cctctgggtc tgcggcgctg
     5161 aacgttgctt ccggctatgc tttcggctgc gttattacgg ctatgccagg gtttgccccg
     5221 gtgacagaat ggctggttgg cattgccgca tctttcgggc cgctgctctc ggcggttatc
     5281 accaccaaca tcatgtgcgg cattacggga tcggcatctg gcggtctgac cattgccctg
     5341 tcggcattgg gcgaccagtg ggcggcgatg gcgattaccg cggggattcc tctggaagtc
     5401 ttgcaccgta tcgtagccgt ggcttcggtt ggtattgacc cggttccgca ttgcggcgct
     5461 ttggtaacac ttctcgccat ctgcggactt acgcacaatg aatcctactt cgatattgcc
     5521 gtgattatgg gcatgaagtt cttggtgccg ttcctgtgca ttatcttcta tatgctgacg
     5581 ggcatctgtt aaagcataat aaaaaatccg gtatatccct tgacgggata taccggattt
     5641 ttttattatc aggtgttttt taagggttcg taagcgtcgg tgtggagaaa ttcccgttcg
     5701 atgacctggc cgttttgttt ccatagtcgg taaagggaag gtcgcatgga acttccttcc
     5761 gtgacgaggg caatgctctt gccagccagg tcggccttgg tgcccagtac ataaaccgtc
     5821 agggcgctgc cgctgttggc aacggtgagg tagaccggat ggggcagagg attgcggaaa
     5881 acgaagtcga taaggccatc agctacagtg gcatctcgtc cggcagggac ataggaggac
     5941 gaagcaaaat gtcctgtgcg ttccacaggg gtcaggcccg ccagtaaaat ggcgttgtag
     6001 agggtggaac tgacctgaca gacgccgcct cctacatcaa cagcgtgttc tccatagatg
     6061 atgacaccgg cgtttttata gccggcttcg cgtgtgcgag gtcctacggt atcgttgaag
     6121 gacaaggtgg caccgctgcg gatcaatgct ccttgtaaat gactggcggc aagacctata
     6181 ttatcgccac gatctccagg atagaaacgg gtcgtatagg agcctaaaat gccatccatg
     6241 gaagcaaggt cattgtcctg tacaaagggg agctgttcag cgggagacag ctcttttttt
     6301 acggttagat taaaggtttt gaaatccggt gccagttcgg cggcaagtgg ctcaatctcc
     6361 aagcttagtc cggttacggc tggtgtttta cggatactgc catcagccag cagggtgaca
     6421 ctgccgtttt tgggtggagt atcgatggcg gtttttattt gctgcagttt gctgttgagg
     6481 agttgttcgt caaagctggc atccatggtg accgttgcgc caaagatagc ataacgcatc
     6541 tgattgatga tgttttcaat aggtgttccg tcccgtccga tattataagc cgtttccaca
     6601 gcctcatcca cattgccatg aaggtttata tcggcagggt caatctggaa attgcgttcc
     6661 ttataagtga ggacagctgc cttacgctgt aattttttgg ctgctgtgtc tgtaaagaac
     6721 ttatgggctt cttttttgct caagccggca atcgaggtgc cattagcctg tacacccata
     6781 acaatccggt ccttgttgct gacggtaacg gatacacagc cggcaaccaa tacgactgct
     6841 atggcagtga ctgtggttat ggctgcgatt ttgcttagag ccatgttgga aagattcata
     6901 atgaaaagac actccctgtt gaagatttga agtaccgctt ccattatact ttttttaggg
     6961 acggggtgca acgtgagttg actttgtttt tttgactttt ttactataac agcttgacat
     7021 tttgactaaa aaaaggtagt ataagaactg tgcttagcac tcggcattaa tgagtgctaa
     7081 caaactaacg acgtatttca taatatagga ggaagatacc tatgattaag ccattgggcg
     7141 aaagagttgt catcgaagtt gctgaaggcg atgtaaagac cgccagcggg attgtactgc
     7201 cggacacggc taaagaaaag ccccagaagg gcacggttgt agctgtaggt acgggcaaac
     7261 ttctggaaaa cggtgagcgc gctgctatgg aagtaaaagc tggcgacacg gttgttttct
     7321 ccaagtactc cggttccgaa gttaaagttg atgataagga atacctgatt gtccgcgaaa
     7381 gcgatattct ggcaattctc taataagcgt attttctgga ggtaatataa atggctaaac
     7441 agattctgtt tgacgaagaa gctcgccgcg ctctgggccg cggtgttgat gcactggcta
     7501 acgccgtaaa agtaaccctt ggccctaaag gccgcaacgt tgtgctcgaa aagaaattcg
     7561 gcgctccgac catcaccaac gatggtgtaa cgattgctcg cgacatcgaa ctcgaagatc
     7621 cgttcgaaaa catgggcgct cagctcgtta aagaagttgc taccaagacc aacgatatcg
     7681 ctggtgatgg tacgacgacg gcaacgctcc tcgcacaggc tatgattcgt gaaggtatgc
     7741 gcaacgttgt tgctggcgca aacccgatga tcatcaaaaa gggtatcgac aaggctgtag
     7801 ctgctctggt tgacgaaatc cagtccaagg ctaagacgat tgaaagcaag gctgacatcg
     7861 ctcaggttgc tacgatttct tccgctaacg aagaaacggg cgaactcatc gcggaagcta
     7921 tggaaaaagt tggtaaagac ggcgttatca ccgttgaaga atccaagtcc atggccacga
     7981 acctctccgt tgtagaaggt atgcagttcg accgcggcta catctccccg tacctcgtaa
     8041 cggatacgga caagatggaa gctgttctcg atgacccgta catcctgatc acggatcgca
     8101 agatttccgc tatcgcagat atcctgccga ttctggaaca ggttgtaaaa cagggcaagc
     8161 agctggctgt tatcgctgaa gatgttgacg gcgaagctct gacgaccatc gtggtcaaca
     8221 agctccgcgg caccttcaag gctctggctg tgaaggctcc tggcttcggt gaccgccgca
     8281 aggctatgct cgaagatatc gctatcctca cgggtggtac ggttatcagc gaagaactgg
     8341 gccgcaaact cgacagcgta accctcgaag acctcggccg cgctcgtcag attcgttcca
     8401 cgaaggaaga aaccacgatt gttgatggtg taggcgataa ggacgctatc gcagctcgcg
     8461 tagcacagat taagaagcag attgcggaaa cgacttctga cttcgacaag gaaaaactgc
     8521 aggaacgtct ggctaaactg gctggcggcg ttgctgttat cgaaatcggt gctgctaccg
     8581 aagttgaaat gaaggacaag aaataccgca tcgaagatgc cctcaacgca actcgcgctg
     8641 ctgttgaaga aggtatcgta gctggtggtg gcacgacctt catcgacatt ctgccggcac
     8701 tcgacaaaat caacgtggaa ggcgacgaaa aggttggcgt aaacatcgtt cgccgtgcta
     8761 tcgaagaacc ggttcgtcag attgcggaca acgctggtct cgaaggttct gtagttgttg
     8821 aagcagtgaa gaaggctggc gacggcatcg gcttcaacgc tctcaagaac gaatacgttg
     8881 acatgatcaa agctggtatc gttgacccgg ctaaggttac gcgctccgct ctgcagaacg
     8941 ctgcttccat cgcttccatg gttctgacca cggaaacgct ggttgctgac aagccggaag
     9001 aaaaaccggc tatgccggct ggcggtgctc cgggcatggg catgccgggc atgatgtaat
     9061 cacatctcca taaagcataa gaccttcccc tgcgggggaa ggttttttgt tgcaggaatt
     9121 gcatgtaaac tgtagaataa taatcggata tttgatttaa taacaggaga aatgtgatga
     9181 atttaaaacg aagtctgcaa acttttgtgg ttatgggagc cgtatgggca tgttcgctga
     9241 cgtttgctca ggcagcggat aagattttgt ttatccccca tgacaatcgg ccgatttctg
     9301 ctgaggaaac ggcggacgtc gtgcgcaagg cgggctatga tgttgttatg ccgccagaag
     9361 aaatgctgag cagcggttat gaccgttttg gtgatacaga ggcgctatgg aagtggacgc
     9421 aggaaaacct gccgggggcg aaagcggcga tgatttctgc cgacagcatg atttatggcg
     9481 gtttggtgcc ctcccgcaag catgaggagc ctgaggaaaa gctgctgaat agagcgcagc
     9541 ggctggcgga tttacagaag gaaaacccgc agctgaaact ctatgtcttt gcgtcattga
     9601 tgcgtacgcc aaaatccggt gcggccgccg gcgtggagga accggaatac tacagaacat
     9661 acggagccga tattttccgc cggtctggat tgctcgataa gcaggaaact acgccattga
     9721 atccgcatga gaagcaggaa ctgtccaagt tggaagccgc tataccgcag gagatctggc
     9781 aggactggaa aaatcggcgg gataaaaatg tccatgtaag caagaagctt attgatatgg
     9841 caagagctgg cgaactatcc tatctggtta tcggcaagga cgataacgcg ccgttatccc
     9901 agacgcatag ggaggcgagg gaattaaatg cctatgcaca ggggatttcg cccacgagat
     9961 ttcagctgtt ggcagggatt gacgagtttg gtttgctgtt gatgaccaga gccgttaatg
    10021 atatggaaaa tgtgattccg ttcgtctata ccgaatatgc gccgggaaaa ggctatgata
    10081 ccgtaccaag ctattccgat gccaaaatcg gcgattcggt aaaggcggcc atccgtgtgg
    10141 ctggcggtgt gccagtgaat aactccgacc gggcggattt aattcttttg gtcaatacca
    10201 atgccaatgg agcaaccggc gagtcctgga atatgcagga gggaaataag ctgttcccgg
    10261 ccaataatgg caaatggcgg gaaaatacgc aagctatggt gcaaaaagtc aatgactatg
    10321 tgtacctgcg ccgcaatatc gcattggcgg atattgcctt tgccaatggc gccgataatg
    10381 cgctgatgga agccttgcag caaagaaatc tgctttaccg tctgcgcgcg tattccggct
    10441 ggaataccgc cacgaacagc acaggctttg cgctggctac agggatgctt tccagccgca
    10501 tgagtgatga tgactgcgac aagctattga gtatgcgttt cctcgatgat tggggctatc
    10561 agtccaatgt gcgcgggcag gtcggtgcgt tg
//
