GCF_900240005.1_BStabCH16_genomic - 14 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_LR025742.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	terpene	271,736	292,569
Region 1.2	NRPS	595,050	649,692	ornibactin	NRP	100%
Region 1.3	T1PKS	1,784,912	1,832,552
Region 1.4	arylpolyene	3,031,710	3,072,921	APE Vf	Other	10%

NZ_LR025743.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	phosphonate	269,197	310,882	phosphinothricintripeptide	NRP	6%
Region 2.2	terpene	469,948	490,481	N-acyloxyacyl glutamine	Other	50%
Region 2.3	hserlactone	1,188,406	1,209,014
Region 2.4	NRPS	1,602,245	1,652,107	pyochelin	NRP	100%
Region 2.5	terpene	2,361,702	2,385,721

NZ_LR025744.1

Region	Type	From	To
Region 3.1	NRPS	73,626	117,609
Region 3.2	terpene	422,792	444,855
Region 3.3	butyrolactone	756,318	767,373
Region 3.4	RiPP-like	921,978	932,793
Region 3.5	nucleoside	1,204,102	1,225,403

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	terpene	271,736	292,569
Region 1.2	NRPS	595,050	649,692	ornibactin	NRP	100%
Region 1.3	T1PKS	1,784,912	1,832,552
Region 1.4	arylpolyene	3,031,710	3,072,921	APE Vf	Other	10%
Region 2.1	phosphonate	269,197	310,882	phosphinothricintripeptide	NRP	6%
Region 2.2	terpene	469,948	490,481	N-acyloxyacyl glutamine	Other	50%
Region 2.3	hserlactone	1,188,406	1,209,014
Region 2.4	NRPS	1,602,245	1,652,107	pyochelin	NRP	100%
Region 2.5	terpene	2,361,702	2,385,721
Region 3.1	NRPS	73,626	117,609
Region 3.2	terpene	422,792	444,855
Region 3.3	butyrolactone	756,318	767,373
Region 3.4	RiPP-like	921,978	932,793
Region 3.5	nucleoside	1,204,102	1,225,403

No secondary metabolite regions were found in these records:: NZ_LR025745.1

Compact view

NZ_LR025742.1 - Region 1 - terpene

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Location: 271,736 - 292,569 nt. (total: 20,834 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000928.1	0.16	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.16	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001120.1	0.14	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000527.1	0.12	RiPP	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000515.1	0.10	RiPP	geobacillin I	Geobacillus thermodenitrificans NG80-2
BGC0001727.1	0.09	RiPP	paenilan	Paenibacillus polymyxa E681
BGC0000897.1	0.09	Other	dehydrophos	Streptomyces luridus
BGC0000842.1	0.09	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0000668.1	0.08	Terpene, Alkaloid	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830
BGC0001701.1	0.08	RiPP	nisin O	Blautia obeum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000928.1	0.47	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.47	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001120.1	0.44	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000527.1	0.39	RiPP	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000515.1	0.35	RiPP	geobacillin I	Geobacillus thermodenitrificans NG80-2
BGC0001727.1	0.34	RiPP	paenilan	Paenibacillus polymyxa E681
BGC0000897.1	0.33	Other	dehydrophos	Streptomyces luridus
BGC0000842.1	0.32	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0000668.1	0.32	Terpene, Alkaloid	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830
BGC0001701.1	0.30	RiPP	nisin O	Blautia obeum

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025742.1 - Region 2 - NRPS

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Location: 595,050 - 649,692 nt. (total: 54,643 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001721.1	0.73	NRP	ornibactin	Burkholderia cepacia
BGC0000426.1	0.36	NRP	sevadicin	Paenibacillus larvae
BGC0000389.1	0.35	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001479.1	0.34	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000427.1	0.33	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000901.1	0.33	Other	ferrichrome	Aspergillus niger
BGC0001249.1	0.32	NRP	dimethylcoprogen	Alternaria alternata
BGC0000351.1	0.31	NRP	exochelin	Mycolicibacterium smegmatis
BGC0000900.1	0.31	Other	ferrichrome	Aspergillus oryzae
BGC0000348.1	0.31	NRP	ergovaline	Epichloe festucae var. lolii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001721.1	0.90	NRP	ornibactin	Burkholderia cepacia
BGC0000426.1	0.69	NRP	sevadicin	Paenibacillus larvae
BGC0000389.1	0.68	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001479.1	0.67	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000427.1	0.66	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000901.1	0.66	Other	ferrichrome	Aspergillus niger
BGC0001249.1	0.65	NRP	dimethylcoprogen	Alternaria alternata
BGC0000351.1	0.65	NRP	exochelin	Mycolicibacterium smegmatis
BGC0000900.1	0.64	Other	ferrichrome	Aspergillus oryzae
BGC0000348.1	0.64	NRP	ergovaline	Epichloe festucae var. lolii

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 595049 - 649692:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - D-asp - ser) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_567

Search NORINE for peptide: strict or relaxed

AMP-binding (518..923): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGeYTGgitK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

ctg1_568

Search NORINE for peptide: strict or relaxed

AMP-binding (14..417): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAeAaGGisK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

AMP-binding (1084..1487): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (2612..3026): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHVSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

NZ_LR025742.1 - Region 3 - T1PKS

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Location: 1,784,912 - 1,832,552 nt. (total: 47,641 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.32	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001124.1	0.29	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001749.1	0.28	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0000046.1	0.27	Polyketide	depudecin	Alternaria brassicicola
BGC0001067.1	0.26	Polyketide, Terpene	fumagillin, β-trans-bergamotene, fumagillol	Aspergillus fumigatus Af293
BGC0001697.1	0.26	Polyketide	neurosporin A	Neurospora crassa OR74A
BGC0001504.1	0.25	Polyketide	amycomicin	Amycolatopsis sp. AA4
BGC0001340.1	0.24	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0001913.1	0.24	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001205.1	0.23	Polyketide	communesin A, communesin B, communesin C, communesin D, communesin E, communesin G, communesin H	Penicillium expansum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.65	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001124.1	0.62	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001749.1	0.62	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0000046.1	0.60	Polyketide	depudecin	Alternaria brassicicola
BGC0001067.1	0.60	Polyketide, Terpene	fumagillin, β-trans-bergamotene, fumagillol	Aspergillus fumigatus Af293
BGC0001697.1	0.60	Polyketide	neurosporin A	Neurospora crassa OR74A
BGC0001504.1	0.59	Polyketide	amycomicin	Amycolatopsis sp. AA4
BGC0001340.1	0.58	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0001913.1	0.57	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001205.1	0.56	Polyketide	communesin A, communesin B, communesin C, communesin D, communesin E, communesin G, communesin H	Penicillium expansum

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 1784911 - 1832552:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1704

PKS_AT (538..845): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 111.8
Malonyl-CoA: 96.5
Methoxymalonyl-CoA: 89.5
Ethylmalonyl-CoA: 77.4
Propionyl-CoA: 51.5
Isobutyryl-CoA: 46.5
inactive: 40.5
2-Methylbutyryl-CoA: 33.8
trans-1,2-CPDA: 33.6
CHC-CoA: 32.5
fatty_acid: 28.6
Benzoyl-CoA: 27.2
3-Methylbutyryl-CoA: 22.5
Acetyl-CoA: 11.9

NZ_LR025742.1 - Region 4 - arylpolyene

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Location: 3,031,710 - 3,072,921 nt. (total: 41,212 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

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MIBiG comparison

KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001444.1	0.30	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.30	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000632.1	0.26	Terpene, Saccharide	brasilicardin A	Nocardia terpenica
BGC0000866.1	0.25	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000228.1	0.24	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.24	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001723.1	0.24	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000886.1	0.23	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0001897.1	0.22	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000194.1	0.22	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001444.1	0.63	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.63	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000632.1	0.59	Terpene, Saccharide	brasilicardin A	Nocardia terpenica
BGC0000866.1	0.58	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000228.1	0.58	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.58	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001723.1	0.57	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000886.1	0.56	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0001897.1	0.55	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000194.1	0.55	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025743.1 - Region 1 - phosphonate

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Location: 269,197 - 310,882 nt. (total: 41,686 nt) Show pHMM detection rules used

phosphonate: phosphonates

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MIBiG comparison

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.28	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.23	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.19	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0001739.1	0.18	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0001475.1	0.17	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0001440.1	0.16	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001895.1	0.16	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0002036.1	0.16	Other	dehydrofosmidomycin	Streptomyces lavendulae
BGC0000937.1	0.16	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000897.1	0.15	Other	dehydrophos	Streptomyces luridus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.62	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.57	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.50	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0001739.1	0.50	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0001475.1	0.47	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0001440.1	0.47	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001895.1	0.46	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0002036.1	0.46	Other	dehydrofosmidomycin	Streptomyces lavendulae
BGC0000937.1	0.46	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000897.1	0.46	Other	dehydrophos	Streptomyces luridus

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025743.1 - Region 2 - terpene

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Location: 469,948 - 490,481 nt. (total: 20,534 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

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resistance

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.35	Terpene	carotenoid	Myxococcus xanthus
BGC0001684.1	0.28	Other	N-acyloxyacyl glutamine	Klebsiella variicola
BGC0001077.1	0.24	Terpene, Polyketide	alkyl-O-dihydrogeranyl-methoxyhydroquinones	Actinoplanes missouriensis 431
BGC0000634.1	0.21	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0001928.1	0.19	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0000932.1	0.18	Other	tropodithietic acid	Phaeobacter inhibens DSM 17395
BGC0001362.1	0.18	Other	tropodithietic acid	Phaeobacter inhibens DSM 17395
BGC0000563.1	0.17	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0001364.1	0.17	RiPP	cinnamycin B	Actinomadura atramentaria DSM 43919
BGC0001660.1	0.17	RiPP	mathermycin	Marinactinospora thermotolerans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.68	Terpene	carotenoid	Myxococcus xanthus
BGC0001684.1	0.61	Other	N-acyloxyacyl glutamine	Klebsiella variicola
BGC0001077.1	0.57	Terpene, Polyketide	alkyl-O-dihydrogeranyl-methoxyhydroquinones	Actinoplanes missouriensis 431
BGC0000634.1	0.54	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0001928.1	0.51	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0000932.1	0.50	Other	tropodithietic acid	Phaeobacter inhibens DSM 17395
BGC0001362.1	0.50	Other	tropodithietic acid	Phaeobacter inhibens DSM 17395
BGC0000563.1	0.48	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0001364.1	0.48	RiPP	cinnamycin B	Actinomadura atramentaria DSM 43919
BGC0001660.1	0.48	RiPP	mathermycin	Marinactinospora thermotolerans

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025743.1 - Region 3 - hserlactone

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Location: 1,188,406 - 1,209,014 nt. (total: 20,609 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

additional biosynthetic genes

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001973.1	0.19	Other	fervenulin	Streptomyces hiroshimensis
BGC0001972.1	0.19	Other	toxoflavin, fervenulin	Streptomyces hiroshimensis
BGC0000929.1	0.18	Other	xanthothricin	Burkholderia glumae
BGC0001959.1	0.18	Other	taylorflavin A, taylorflavin B	Streptomyces hiroshimensis
BGC0001897.1	0.16	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001120.1	0.15	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000703.1	0.14	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0001149.1	0.12	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0002007.1	0.11	Terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina
BGC0001480.1	0.10	Other	tundrenone	Methylobacter tundripaludum 21/22

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001973.1	0.51	Other	fervenulin	Streptomyces hiroshimensis
BGC0001972.1	0.51	Other	toxoflavin, fervenulin	Streptomyces hiroshimensis
BGC0000929.1	0.50	Other	xanthothricin	Burkholderia glumae
BGC0001959.1	0.50	Other	taylorflavin A, taylorflavin B	Streptomyces hiroshimensis
BGC0001897.1	0.46	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001120.1	0.45	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000703.1	0.43	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0001149.1	0.39	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0002007.1	0.38	Terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina
BGC0001480.1	0.36	Other	tundrenone	Methylobacter tundripaludum 21/22

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025743.1 - Region 4 - NRPS

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Location: 1,602,245 - 1,652,107 nt. (total: 49,863 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000412.1	0.46	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0001050.1	0.30	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001343.1	0.28	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000351.1	0.28	NRP	exochelin	Mycolicibacterium smegmatis
BGC0001538.1	0.26	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001444.1	0.26	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000843.1	0.24	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0000855.1	0.23	Other	ectoine	Methylomicrobium kenyense
BGC0000352.1	0.23	NRP	fimsbactin A	Acinetobacter sp. ADP1
BGC0000852.1	0.23	Other	ectoine	Sporosarcina pasteurii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000412.1	0.76	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0001050.1	0.63	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001343.1	0.62	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000351.1	0.62	NRP	exochelin	Mycolicibacterium smegmatis
BGC0001538.1	0.59	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001444.1	0.59	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000843.1	0.57	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0000855.1	0.56	Other	ectoine	Methylomicrobium kenyense
BGC0000352.1	0.56	NRP	fimsbactin A	Acinetobacter sp. ADP1
BGC0000852.1	0.56	Other	ectoine	Sporosarcina pasteurii

Similar known gene clusters

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 1602244 - 1652107:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg2_1450

Search NORINE for peptide: strict or relaxed

AMP-binding (523..920): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg2_1451

Search NORINE for peptide: strict or relaxed

AMP-binding (573..963): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg2_1453

Search NORINE for peptide: strict or relaxed

AMP-binding (42..447): sal

NRPSPredictor2: sal

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: TLPAQGVICK
Nearest Stachelhaus code:: sal
Stachelhaus code match:: 100% (strong)

NZ_LR025743.1 - Region 5 - terpene

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Location: 2,361,702 - 2,385,721 nt. (total: 24,020 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.29	Terpene	carotenoid	Myxococcus xanthus
BGC0000630.1	0.24	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000640.1	0.24	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000656.1	0.23	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000646.1	0.21	Terpene	β-carotein	uncultured bacterium
BGC0000643.1	0.20	Terpene	carotenoid	Brevundimonas vesicularis
BGC0000634.1	0.20	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000635.1	0.18	Terpene	carotenoid	Paracoccus sp. N81106
BGC0000642.1	0.18	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000641.1	0.17	Terpene	carotenoid	Enterobacteriaceae bacterium DC416

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.62	Terpene	carotenoid	Myxococcus xanthus
BGC0000630.1	0.57	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000640.1	0.57	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000656.1	0.56	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000646.1	0.54	Terpene	β-carotein	uncultured bacterium
BGC0000643.1	0.52	Terpene	carotenoid	Brevundimonas vesicularis
BGC0000634.1	0.52	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000635.1	0.50	Terpene	carotenoid	Paracoccus sp. N81106
BGC0000642.1	0.49	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000641.1	0.49	Terpene	carotenoid	Enterobacteriaceae bacterium DC416

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025744.1 - Region 1 - NRPS

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Location: 73,626 - 117,609 nt. (total: 43,984 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Pfam domains

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Detailed domain annotation

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.32	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001890.1	0.27	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0000417.1	0.27	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001844.1	0.24	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001909.1	0.24	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001758.1	0.24	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.24	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1	0.24	NRP	ambactin	Xenorhabdus miraniensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.65	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001890.1	0.60	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0000417.1	0.60	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001132.1	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001844.1	0.57	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001909.1	0.57	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001758.1	0.57	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.57	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1	0.57	NRP	ambactin	Xenorhabdus miraniensis

Similar known gene clusters

No matches found.

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 73625 - 117609:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal) + (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg3_87

PKS_AT (1..281): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 84.4
Methoxymalonyl-CoA: 58.2
Methylmalonyl-CoA: 51.5
Ethylmalonyl-CoA: 46.4
inactive: 40.8
Propionyl-CoA: 15.5
Isobutyryl-CoA: 15.5
Acetyl-CoA: 15.0
fatty_acid: 13.1
trans-1,2-CPDA: 10.0
CHC-CoA: 9.3
2-Methylbutyryl-CoA: 7.0
Benzoyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg3_89

Search NORINE for peptide: strict or relaxed

AMP-binding (502..909): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DmYHLGLmdK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 70% (weak)

NZ_LR025744.1 - Region 2 - terpene

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Location: 422,792 - 444,855 nt. (total: 22,064 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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resistance

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MIBiG comparison

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001120.1	0.22	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000783.1	0.17	Saccharide	O-antigen	Xanthomonas oryzae pv. oryzae
BGC0000780.1	0.17	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0001736.1	0.14	NRP	pepteridine A, pepteridine B	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000686.1	0.13	Terpene	helvolic acid	Aspergillus fumigatus Af293
BGC0000663.1	0.10	Terpene	hopene	Streptomyces coelicolor A3(2)
BGC0000934.1	0.08	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0001149.1	0.08	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0000926.1	0.08	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000221.1	0.07	Polyketide	erdacin	uncultured soil bacterium V167

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001120.1	0.55	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000783.1	0.49	Saccharide	O-antigen	Xanthomonas oryzae pv. oryzae
BGC0000780.1	0.48	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0001736.1	0.43	NRP	pepteridine A, pepteridine B	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000686.1	0.41	Terpene	helvolic acid	Aspergillus fumigatus Af293
BGC0000663.1	0.35	Terpene	hopene	Streptomyces coelicolor A3(2)
BGC0000934.1	0.31	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0001149.1	0.31	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0000926.1	0.30	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000221.1	0.29	Polyketide	erdacin	uncultured soil bacterium V167

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025744.1 - Region 3 - butyrolactone

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Location: 756,318 - 767,373 nt. (total: 11,056 nt) Show pHMM detection rules used

butyrolactone: AfsA

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000846.1	0.28	Other	tabtoxin	Pseudomonas syringae
BGC0000885.1	0.26	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000937.1	0.22	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001739.1	0.22	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0001538.1	0.20	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001374.1	0.19	Other	thienodolin	Streptomyces albogriseolus
BGC0000231.1	0.16	Polyketide	griseusin	Streptomyces griseus
BGC0000845.1	0.15	Other (Non-NRP beta-lactam)	clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0000509.1	0.15	RiPP	epilancin 15x	Staphylococcus epidermidis
BGC0001917.1	0.15	Polyketide	5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals	Streptomyces nigrescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000846.1	0.61	Other	tabtoxin	Pseudomonas syringae
BGC0000885.1	0.59	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000937.1	0.55	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001739.1	0.55	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0001538.1	0.52	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001374.1	0.51	Other	thienodolin	Streptomyces albogriseolus
BGC0000231.1	0.47	Polyketide	griseusin	Streptomyces griseus
BGC0000845.1	0.46	Other (Non-NRP beta-lactam)	clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0000509.1	0.45	RiPP	epilancin 15x	Staphylococcus epidermidis
BGC0001917.1	0.44	Polyketide	5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals	Streptomyces nigrescens

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025744.1 - Region 4 - RiPP-like

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Location: 921,978 - 932,793 nt. (total: 10,816 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001882.1	0.18	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0001521.1	0.17	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000255.1	0.08	Polyketide	pederin	Uncultured bacterium
BGC0001122.1	0.07	NRP, Polyketide	dihydroisoflavipucine, isoflavipucine	Aspergillus terreus NIH2624
BGC0001650.1	0.07	NRP	Le-pyrrolopyrazines	Lysobacter enzymogenes
BGC0001281.1	0.05	Polyketide	ustilagic acid	Ustilago maydis 521
BGC0001591.1	0.05	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.05	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000700.1	0.05	Saccharide	istamycin	Streptomyces tenjimariensis
BGC0001195.1	0.05	NRP, Polyketide	nocardiopsin A, nocardiopsin B, nocardiopsin C, nocardiopsin D	Nocardiopsis sp. CMB-M0232

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001882.1	0.50	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0001521.1	0.49	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000255.1	0.30	Polyketide	pederin	Uncultured bacterium
BGC0001122.1	0.28	NRP, Polyketide	dihydroisoflavipucine, isoflavipucine	Aspergillus terreus NIH2624
BGC0001650.1	0.27	NRP	Le-pyrrolopyrazines	Lysobacter enzymogenes
BGC0001281.1	0.23	Polyketide	ustilagic acid	Ustilago maydis 521
BGC0001591.1	0.23	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.23	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000700.1	0.23	Saccharide	istamycin	Streptomyces tenjimariensis
BGC0001195.1	0.22	NRP, Polyketide	nocardiopsin A, nocardiopsin B, nocardiopsin C, nocardiopsin D	Nocardiopsis sp. CMB-M0232

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_LR025744.1 - Region 5 - nucleoside

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Location: 1,204,102 - 1,225,403 nt. (total: 21,302 nt) Show pHMM detection rules used

nucleoside: (LipM or LipV or LipU or ToyB or TunD or pur6 or pur10 or nikJ or nikO or truD)

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Analysis type:

Reference	nucleoside	Similarity score	Type	Compound(s)	Organism
BGC0000877.1		0.10	Other	polyoxin A, polyoxin H	Streptomyces cacaoi subsp. asoensis

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0000877.1		0.36	Other	polyoxin A, polyoxin H	Streptomyces cacaoi subsp. asoensis

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Detailed Pfam domain annotation

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