LOCUS       NC_013740.1            21631 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_013740.1 Acidaminococcus fermentans DSM 20731, complete sequence.
ACCESSION   NC_013740
VERSION     NC_013740.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:23:39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 625052
            Orig. end    :: 646683
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21631
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[635052:636683]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11631
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21631
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21631
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             187..642
                     /locus_tag="ctg1_537"
                     /transl_table=11
                     /translation="MMTKKLVAYFSASGVTAAKAKKLAEVVGADLYEIAPKDRYTNADL
                     NWTNKKARSTVEMNDPASRPELKENGLDLTGYDTVYIGFPIWWYTAPHIIRSFLEQNKL
                     TGVDIVLFATSGGSSISKAYRDLRKAYPKLNITNGVLLNGSISGNLA"
     PFAM_domain     196..636
                     /aSDomain="Flavodoxin_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12682.9"
                     /description="Flavodoxin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_537_0001"
                     /evalue="4.60E-47"
                     /label="ctg1_537"
                     /locus_tag="ctg1_537"
                     /protein_end="150"
                     /protein_start="3"
                     /score="159.7"
                     /tool="antismash"
                     /translation="KKLVAYFSASGVTAAKAKKLAEVVGADLYEIAPKDRYTNADLNWT
                     NKKARSTVEMNDPASRPELKENGLDLTGYDTVYIGFPIWWYTAPHIIRSFLEQNKLTGV
                     DIVLFATSGGSSISKAYRDLRKAYPKLNITNGVLLNGSISGNL"
     CDS             707..1825
                     /locus_tag="ctg1_538"
                     /transl_table=11
                     /translation="MDRREFLKISGLGALALVLSSCGFSKQTASSAQLTGGGSSATGKE
                     KVAGTGGDKYIPPEQRQGNESVVYFTRDLSAAGLLKIYETIAGNMTGRVGIKLHTGEPH
                     GPNIIPRPWVKQLMEAKLPNARIVETNTYYGGARYTTEEHRKTLAVNGWDFAPVDILDE
                     EGTTMLPVKGGKWFTEMSVGSHLLNYDSLLVLTHFKGHTMGGFGGSDKNIGIGCADGRI
                     GKKMIHSGEGGSQWGIDKEEFMERLTESSKATADHFGNHIAYINVLRNMSVSCDCEGTG
                     AQPVVTPNIGILASTDILAADQASVDLVYALPEKDRHALVERMESRHGLRQLSYMKELG
                     MGCDRYVLLDLDHGSQPLTLADAVKDVKPFEG"
     PFAM_domain     986..1627
                     /aSDomain="DUF362"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04015.14"
                     /description="Domain of unknown function (DUF362)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_538_0002"
                     /evalue="3.70E-36"
                     /label="ctg1_538"
                     /locus_tag="ctg1_538"
                     /protein_end="307"
                     /protein_start="93"
                     /score="125.2"
                     /tool="antismash"
                     /translation="VGIKLHTGEPHGPNIIPRPWVKQLMEAKLPNARIVETNTYYGGAR
                     YTTEEHRKTLAVNGWDFAPVDILDEEGTTMLPVKGGKWFTEMSVGSHLLNYDSLLVLTH
                     FKGHTMGGFGGSDKNIGIGCADGRIGKKMIHSGEGGSQWGIDKEEFMERLTESSKATAD
                     HFGNHIAYINVLRNMSVSCDCEGTGAQPVVTPNIGILASTDILAADQASVD"
     CDS             1969..2406
                     /locus_tag="ctg1_539"
                     /transl_table=11
                     /translation="MDERLKQFAGFALALVMTTCMGIHYGEAAVMENETKKPVKIVQTA
                     GRDVLGEFAPEFARYNDDILFGEVWSANDKLSLHDRSIVTVSALISQGITDSSLKYHIT
                     SARNNGVTKEEMVQIITQLGFYAGWPKAWAAFRLAKEVYEA"
     PFAM_domain     2131..2391
                     /aSDomain="CMD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02627.22"
                     /description="Carboxymuconolactone decarboxylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_539_0003"
                     /evalue="5.20E-20"
                     /label="ctg1_539"
                     /locus_tag="ctg1_539"
                     /protein_end="141"
                     /protein_start="54"
                     /score="71.4"
                     /tool="antismash"
                     /translation="PEFARYNDDILFGEVWSANDKLSLHDRSIVTVSALISQGITDSSL
                     KYHITSARNNGVTKEEMVQIITQLGFYAGWPKAWAAFRLAKE"
     CDS             2507..2710
                     /locus_tag="ctg1_540"
                     /transl_table=11
                     /translation="MDEKLRENLEAAGCPDEVIRKVQQMEGTQQQTLELRKYRRCLLEK
                     VHREQERLTNLDYLLYQLEKQA"
     CDS             complement(2790..3683)
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 145.2; E-value: 4e-44)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_541"
                     /transl_table=11
                     /translation="MEIRTLKYFLAVAREQNMTEAANLLFVTQPTLSRQMADLEKELGK
                     KLFIRSNRSTTLTEEGMHLRQRAEEILALVEQTKSEIKDEDLNLTGCIRIGAGITYLVH
                     YLTDTFADLRKENPHLTIEMLTGNADIIQEKLEHGLLDFGLFIQPFNVENYNYLELPGK
                     NRLGIVTSIHSPWAKLDAVTPENILGIPLMTSSRHNNRSFDLEGWSKGKISVEKLNIVG
                     TMDLSCNTNPLVFQQVANLLCLDRLEHHESPELKFIPLEPAYEVSSLVAWKKYRLLSHS
                     SQVFLERLKEKVNPEK"
     PFAM_domain     complement(2808..3416)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_541_0005"
                     /evalue="2.20E-14"
                     /label="ctg1_541"
                     /locus_tag="ctg1_541"
                     /protein_end="292"
                     /protein_start="89"
                     /score="53.5"
                     /tool="antismash"
                     /translation="TGCIRIGAGITYLVHYLTDTFADLRKENPHLTIEMLTGNADIIQE
                     KLEHGLLDFGLFIQPFNVENYNYLELPGKNRLGIVTSIHSPWAKLDAVTPENILGIPLM
                     TSSRHNNRSFDLEGWSKGKISVEKLNIVGTMDLSCNTNPLVFQQVANLLCLDRLEHHES
                     PELKFIPLEPAYEVSSLVAWKKYRLLSHSSQVFLERLKEK"
     PFAM_domain     complement(3501..3677)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_541_0004"
                     /evalue="7.10E-21"
                     /label="ctg1_541"
                     /locus_tag="ctg1_541"
                     /protein_end="61"
                     /protein_start="2"
                     /score="74.0"
                     /tool="antismash"
                     /translation="IRTLKYFLAVAREQNMTEAANLLFVTQPTLSRQMADLEKELGKKL
                     FIRSNRSTTLTEEG"
     CDS             3860..4105
                     /locus_tag="ctg1_542"
                     /transl_table=11
                     /translation="VDLVDKLKEYSVLTDEEYKALLQTEDPLLRDKLFRGVQEAMNYVF
                     HRRVYFQGVLEFSNHGSIINVGVLWTLLFTRPLVLR"
     CDS             5001..5810
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 189; E-value: 1.9e-57)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_543"
                     /transl_table=11
                     /translation="MSLKMIAMDLDGTLLDEEKNIAPEDAAAVKDAVAAGYYVTLATGR
                     MYRSALPYAQELRLTHPLVVYNGALIRDPGTGENLGQWPLPLDVAQSVLDDLLGWGIYV
                     QAYVDDTLWAPRDCEEVRFYSRFSRVPYEVKTEAIRHLPQAPHKLLVISDQVRTLRPEL
                     EEKYRGKIKIVSSSKGFLEVTAPGTNKWHALQALAAREGIREEEILCVGDSDNDLEMIS
                     HAGFGVAMGNASDPVREAARVVTAPNTRNGVARIIRTILTRQVEVPV"
     aSDomain        5013..5690
                     /aSDomain="TIGR01484"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IIB: HAD hydrolase, family IIB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_543_0002"
                     /evalue="2.50E-24"
                     /identifier="TIGR01484"
                     /label="ctg1_543"
                     /locus_tag="ctg1_543"
                     /protein_end="230"
                     /protein_start="4"
                     /score="84.5"
                     /tool="antismash"
                     /translation="MIAMDLDGTLLDEEKNIAPEDAAAVKDAVAAGYYVTLATGRMYRS
                     ALPYAQELRLTHPLVVYNGALIRDPGTGENLGQWPLPLDVAQSVLDDLLGWGIYVQAYV
                     DDTLWAPRDCEEVRFYSRFSRVPYEVKTEAIRHLPQAPHKLLVISDQVRTLRPELEEKY
                     RGKIKIVSSSKGFLEVTAPGTNKWHALQALAAREGIREEEILCVGDSDNDLEMISHAGF
                     GVAM"
     aSDomain        5013..5771
                     /aSDomain="TIGR00099"
                     /aSTool="tigrfam"
                     /description="Cof-subfamily: Cof-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_543_0001"
                     /evalue="2.00E-53"
                     /identifier="TIGR00099"
                     /label="ctg1_543"
                     /locus_tag="ctg1_543"
                     /protein_end="257"
                     /protein_start="4"
                     /score="179.6"
                     /tool="antismash"
                     /translation="MIAMDLDGTLLDEEKNIAPEDAAAVKDAVAAGYYVTLATGRMYRS
                     ALPYAQELRLTHPLVVYNGALIRDPGTGENLGQWPLPLDVAQSVLDDLLGWGIYVQAYV
                     DDTLWAPRDCEEVRFYSRFSRVPYEVKTEAIRHLPQAPHKLLVISDQVRTLRPELEEKY
                     RGKIKIVSSSKGFLEVTAPGTNKWHALQALAAREGIREEEILCVGDSDNDLEMISHAGF
                     GVAMGNASDPVREAARVVTAPNTRNGVARII"
     PFAM_domain     5016..5771
                     /aSDomain="Hydrolase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08282.14"
                     /description="haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_543_0006"
                     /evalue="3.20E-57"
                     /label="ctg1_543"
                     /locus_tag="ctg1_543"
                     /protein_end="257"
                     /protein_start="5"
                     /score="194.3"
                     /tool="antismash"
                     /translation="IAMDLDGTLLDEEKNIAPEDAAAVKDAVAAGYYVTLATGRMYRSA
                     LPYAQELRLTHPLVVYNGALIRDPGTGENLGQWPLPLDVAQSVLDDLLGWGIYVQAYVD
                     DTLWAPRDCEEVRFYSRFSRVPYEVKTEAIRHLPQAPHKLLVISDQVRTLRPELEEKYR
                     GKIKIVSSSKGFLEVTAPGTNKWHALQALAAREGIREEEILCVGDSDNDLEMISHAGFG
                     VAMGNASDPVREAARVVTAPNTRNGVARII"
     CDS             5892..6752
                     /locus_tag="ctg1_544"
                     /transl_table=11
                     /translation="MARTLLITGMSGAGKTQVMRTLEDLGYFCVDNLPPTFIPKFIELC
                     LQNKNGGAQLALVVDIRGGKFFKDLNRVLDQLNQSSVPYELVFLDADDATLIRRYKETR
                     RRHPLAGKNGLSADIARERDILSQIRQRATTIIDTSRTTTKELRQKIVQLFGKGGELPP
                     MNIVVQSFGFKYGIPLDCDMVFDVRFLPNPFYIPELKNLCGNDQPVMDYIQEKPVTGEF
                     EEKLFSLIQFLLPQYVQEGKSQLMIGVGCTGGRHRSVFIANALGRFIEKCGYGVQVIHR
                     DLIKK"
     PFAM_domain     5904..6746
                     /aSDomain="ATP_bind_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03668.17"
                     /description="P-loop ATPase protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_544_0007"
                     /evalue="2.90E-100"
                     /label="ctg1_544"
                     /locus_tag="ctg1_544"
                     /protein_end="285"
                     /protein_start="4"
                     /score="335.3"
                     /tool="antismash"
                     /translation="LLITGMSGAGKTQVMRTLEDLGYFCVDNLPPTFIPKFIELCLQNK
                     NGGAQLALVVDIRGGKFFKDLNRVLDQLNQSSVPYELVFLDADDATLIRRYKETRRRHP
                     LAGKNGLSADIARERDILSQIRQRATTIIDTSRTTTKELRQKIVQLFGKGGELPPMNIV
                     VQSFGFKYGIPLDCDMVFDVRFLPNPFYIPELKNLCGNDQPVMDYIQEKPVTGEFEEKL
                     FSLIQFLLPQYVQEGKSQLMIGVGCTGGRHRSVFIANALGRFIEKCGYGVQVIHRDLIK
                     "
     CDS             6763..8136
                     /locus_tag="ctg1_545"
                     /transl_table=11
                     /translation="MKWIKWLYPGLNLKRWLFLFALGAVLACVGVTLIFNYQFVGLLEA
                     LVLQFISSVGGEYYQSTITGLGAFSVVLGILCMCLGATHVIKTIINAVMPGEKESLREL
                     IFTQQKLDKGPSVVVIGGGTGLSVLLRGIKLITNNCTAVVTTADDGGSSGRLRKELGIL
                     PPGDMRNCLVALSDTEPLMEKVMQYRFKSSALSGHNLGNLFIAAMSDVEGGDMEKGIAA
                     TCEILKVRGHVWPNTTDNIQLKAKMDDGSTVVGESSITASPHKIVQLMTEPENPRASQR
                     AVDAILKADAIILGPGSLYTSVLASLIVPGIRDAVIRSKAVKIYVCNVMTQPGETDGYG
                     AYEHVRALIRHMGCQCLDYVVVNEQKASPDILAKYEKEGAMPVSPDVEKIEQLGIDCVP
                     AKLLNDSDLVRHNPLKLAKTIIALIYRLKLFGKGIRFFDYFFARQTMQELRKHARKEH"
     PFAM_domain     7111..7968
                     /aSDomain="CofD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01933.20"
                     /description="2-phospho-L-lactate transferase CofD"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_545_0008"
                     /evalue="1.90E-104"
                     /label="ctg1_545"
                     /locus_tag="ctg1_545"
                     /protein_end="402"
                     /protein_start="116"
                     /score="349.1"
                     /tool="antismash"
                     /translation="VVVIGGGTGLSVLLRGIKLITNNCTAVVTTADDGGSSGRLRKELG
                     ILPPGDMRNCLVALSDTEPLMEKVMQYRFKSSALSGHNLGNLFIAAMSDVEGGDMEKGI
                     AATCEILKVRGHVWPNTTDNIQLKAKMDDGSTVVGESSITASPHKIVQLMTEPENPRAS
                     QRAVDAILKADAIILGPGSLYTSVLASLIVPGIRDAVIRSKAVKIYVCNVMTQPGETDG
                     YGAYEHVRALIRHMGCQCLDYVVVNEQKASPDILAKYEKEGAMPVSPDVEKIEQLGIDC
                     VPAKL"
     aSDomain        7111..8031
                     /aSDomain="TIGR01826"
                     /aSTool="tigrfam"
                     /description="CofD_related: conserved hypothetical protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_545_0003"
                     /evalue="2.20E-114"
                     /identifier="TIGR01826"
                     /label="ctg1_545"
                     /locus_tag="ctg1_545"
                     /protein_end="423"
                     /protein_start="116"
                     /score="380.1"
                     /tool="antismash"
                     /translation="VVVIGGGTGLSVLLRGIKLITNNCTAVVTTADDGGSSGRLRKELG
                     ILPPGDMRNCLVALSDTEPLMEKVMQYRFKSSALSGHNLGNLFIAAMSDVEGGDMEKGI
                     AATCEILKVRGHVWPNTTDNIQLKAKMDDGSTVVGESSITASPHKIVQLMTEPENPRAS
                     QRAVDAILKADAIILGPGSLYTSVLASLIVPGIRDAVIRSKAVKIYVCNVMTQPGETDG
                     YGAYEHVRALIRHMGCQCLDYVVVNEQKASPDILAKYEKEGAMPVSPDVEKIEQLGIDC
                     VPAKLLNDSDLVRHNPLKLAKTIIAL"
     CDS             8139..9068
                     /locus_tag="ctg1_546"
                     /transl_table=11
                     /translation="MSFSHDVKNEIARSEGENHDCEKAELFGLLRISGAVSLSGRKVGI
                     HFTTENAALARRVLRLLKNNFPVQTEVIVTRSRRLKKNNRYQVHVIPSDEARTALSRLH
                     LLSPLEEAGSALLKKEGEKRAFLRGVFLAGGSVNKPISDYHLELICDSLDMGQFIQKIM
                     KGFSLPARIVDRKNSYIVYLKEGNAIAGFLSLIGASNSYLEFENVRVLKDMRNKVNRQV
                     NCETANLNKVVQAAVRQLNAIRVIEETVGLSTLPEPLQEAARLRRDHQDLSVGELAALT
                     EDNVGKSGFNHRLKKLEQLAEKLKDGEQ"
     aSDomain        8151..9044
                     /aSDomain="TIGR00647"
                     /aSTool="tigrfam"
                     /description="DNA_bind_WhiA: DNA-binding protein WhiA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_546_0004"
                     /evalue="2.60E-90"
                     /identifier="TIGR00647"
                     /label="ctg1_546"
                     /locus_tag="ctg1_546"
                     /protein_end="302"
                     /protein_start="4"
                     /score="300.8"
                     /tool="antismash"
                     /translation="HDVKNEIARSEGENHDCEKAELFGLLRISGAVSLSGRKVGIHFTT
                     ENAALARRVLRLLKNNFPVQTEVIVTRSRRLKKNNRYQVHVIPSDEARTALSRLHLLSP
                     LEEAGSALLKKEGEKRAFLRGVFLAGGSVNKPISDYHLELICDSLDMGQFIQKIMKGFS
                     LPARIVDRKNSYIVYLKEGNAIAGFLSLIGASNSYLEFENVRVLKDMRNKVNRQVNCET
                     ANLNKVVQAAVRQLNAIRVIEETVGLSTLPEPLQEAARLRRDHQDLSVGELAALTEDNV
                     GKSGFNHRLKKLEQLAE"
     PFAM_domain     8196..8453
                     /aSDomain="WhiA_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10298.11"
                     /description="WhiA N-terminal LAGLIDADG-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_546_0009"
                     /evalue="1.90E-24"
                     /label="ctg1_546"
                     /locus_tag="ctg1_546"
                     /protein_end="105"
                     /protein_start="19"
                     /score="85.6"
                     /tool="antismash"
                     /translation="DCEKAELFGLLRISGAVSLSGRKVGIHFTTENAALARRVLRLLKN
                     NFPVQTEVIVTRSRRLKKNNRYQVHVIPSDEARTALSRLHL"
     PFAM_domain     8508..8783
                     /aSDomain="LAGLIDADG_WhiA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14527.8"
                     /description="WhiA LAGLIDADG-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_546_0010"
                     /evalue="1.10E-32"
                     /label="ctg1_546"
                     /locus_tag="ctg1_546"
                     /protein_end="215"
                     /protein_start="123"
                     /score="112.1"
                     /tool="antismash"
                     /translation="RAFLRGVFLAGGSVNKPISDYHLELICDSLDMGQFIQKIMKGFSL
                     PARIVDRKNSYIVYLKEGNAIAGFLSLIGASNSYLEFENVRVLKDMR"
     PFAM_domain     8790..9041
                     /aSDomain="HTH_WhiA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02650.16"
                     /description="WhiA C-terminal HTH domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_546_0011"
                     /evalue="3.30E-31"
                     /label="ctg1_546"
                     /locus_tag="ctg1_546"
                     /protein_end="301"
                     /protein_start="217"
                     /score="107.6"
                     /tool="antismash"
                     /translation="VNRQVNCETANLNKVVQAAVRQLNAIRVIEETVGLSTLPEPLQEA
                     ARLRRDHQDLSVGELAALTEDNVGKSGFNHRLKKLEQLA"
     CDS             9065..9916
                     /locus_tag="ctg1_547"
                     /transl_table=11
                     /translation="MKKLIIFLAIVAALAGFAYGGYEYVKRDFPRFCEETVPIFAYHRV
                     EPGHDDPYTMPPEQFDEQMKYLKEQGWKTMTLAEYVKGRKEGRKFHKECVLIFDDGYLD
                     NLTYAAPILKKYGFVGNMYMAVKYEGWPGYLDWNQEHELLKYGWALGSHTFNHKPLQSL
                     TPEQVDYELTSSMQHMRGIYNPPEGLTFSYPNGSASDAIAAQVKKAGYIAGVDGRVGVN
                     TDKVDLMRLRRVNVFQNKPENLGCFQYDLKRAQIQSYIDQTGLDTDWLIHKYYELKGKL
                     HL"
     PFAM_domain     9338..9697
                     /aSDomain="Polysacc_deac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01522.23"
                     /description="Polysaccharide deacetylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_547_0012"
                     /evalue="1.40E-18"
                     /label="ctg1_547"
                     /locus_tag="ctg1_547"
                     /protein_end="211"
                     /protein_start="91"
                     /score="67.1"
                     /tool="antismash"
                     /translation="KECVLIFDDGYLDNLTYAAPILKKYGFVGNMYMAVKYEGWPGYLD
                     WNQEHELLKYGWALGSHTFNHKPLQSLTPEQVDYELTSSMQHMRGIYNPPEGLTFSYPN
                     GSASDAIAAQVKKAGY"
     CDS             10001..10147
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_548"
                     /sec_met_domain="TIGR03973 (E-value: 8.2e-26, bitscore:
                     86.6, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 8.5e-25, bitscore: 83.4,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAKRIKTVNKEMLKKTLRTGGCGECPASCQSACKTSCTVGNQVC
                     EKA"
     aSDomain        10010..10138
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_548_0005"
                     /evalue="1.80E-25"
                     /identifier="TIGR03973"
                     /label="ctg1_548"
                     /locus_tag="ctg1_548"
                     /protein_end="46"
                     /protein_start="3"
                     /score="86.6"
                     /tool="antismash"
                     /translation="KRIKTVNKEMLKKTLRTGGCGECPASCQSACKTSCTVGNQVCE"
     PFAM_domain     10010..10141
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_548_0013"
                     /evalue="7.70E-24"
                     /label="ctg1_548"
                     /locus_tag="ctg1_548"
                     /protein_end="47"
                     /protein_start="3"
                     /score="83.4"
                     /tool="antismash"
                     /translation="KRIKTVNKEMLKKTLRTGGCGECPASCQSACKTSCTVGNQVCEK"
     CDS             10225..11631
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_549"
                     /sec_met_domain="PF04055 (E-value: 1.3e-13, bitscore: 48.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-13, bitscore: 47.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.1e-21, bitscore:
                     73.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.5e-06, bitscore: 24.8,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 9.3e-22,
                     bitscore: 74.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LIHRMHLDDNYVVLDVNSGAVHIIDAMIYDILGFYDGTNAEATKA
                     HFAGKYPAEDVAEALDELQELQKAGLLFSPDFPVPDTFSDEPVLKSLCLHVAHDCNLRC
                     GYCFADTGDFGGHRALMSKEVARKAIEFAIAGSKQRHNLELDLFGGEPLMNMPVVKYIV
                     DYVRQREKETGKNIKLTLTTNGTLLTDEIVKYLNDNRVMLVLSLDGSKKTHDNMRPYPG
                     HVGSYDAAVKGFRKVIESRHGKNYYLRGTYTHYNTHFCDDVLAMLDVGSEISMEPVVGT
                     TEPWVLTEEDWPTLDKEYEKLARAYLARKRAGEAFDFFHFNVALDNGPCVAKRLAGCGA
                     GHEYFAITPEGDIYPCHQFVGREKYKMGTLDTGIVKKDMVQYFRHMHVMKKEDCRTCWA
                     RFFCSGGCHANADLANGTIEKPYAYGCRIQKKRLEMAIILQALLTEDVKEGGADHRPVI
                     DNFKFQVEKK"
     aSDomain        10228..11547
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_549_0006"
                     /evalue="9.70E-175"
                     /identifier="TIGR03974"
                     /label="ctg1_549"
                     /locus_tag="ctg1_549"
                     /protein_end="441"
                     /protein_start="1"
                     /score="579.7"
                     /tool="antismash"
                     /translation="IHRMHLDDNYVVLDVNSGAVHIIDAMIYDILGFYDGTNAEATKAH
                     FAGKYPAEDVAEALDELQELQKAGLLFSPDFPVPDTFSDEPVLKSLCLHVAHDCNLRCG
                     YCFADTGDFGGHRALMSKEVARKAIEFAIAGSKQRHNLELDLFGGEPLMNMPVVKYIVD
                     YVRQREKETGKNIKLTLTTNGTLLTDEIVKYLNDNRVMLVLSLDGSKKTHDNMRPYPGH
                     VGSYDAAVKGFRKVIESRHGKNYYLRGTYTHYNTHFCDDVLAMLDVGSEISMEPVVGTT
                     EPWVLTEEDWPTLDKEYEKLARAYLARKRAGEAFDFFHFNVALDNGPCVAKRLAGCGAG
                     HEYFAITPEGDIYPCHQFVGREKYKMGTLDTGIVKKDMVQYFRHMHVMKKEDCRTCWAR
                     FFCSGGCHANADLANGTIEKPYAYGCRIQKKRLEMAIILQA"
     PFAM_domain     10501..10860
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_549_0014"
                     /evalue="8.60E-13"
                     /label="ctg1_549"
                     /locus_tag="ctg1_549"
                     /protein_end="212"
                     /protein_start="92"
                     /score="49.0"
                     /tool="antismash"
                     /translation="CLHVAHDCNLRCGYCFADTGDFGGHRALMSKEVARKAIEFAIAGS
                     KQRHNLELDLFGGEPLMNMPVVKYIVDYVRQREKETGKNIKLTLTTNGTLLTDEIVKYL
                     NDNRVMLVLSLDGSKK"
     PFAM_domain     11236..11418
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_549_0015"
                     /evalue="2.50E-05"
                     /label="ctg1_549"
                     /locus_tag="ctg1_549"
                     /protein_end="398"
                     /protein_start="337"
                     /score="24.7"
                     /tool="antismash"
                     /translation="CGAGHEYFAITPEGDIYPCHQFVGREKYKMGTLDTGIVKKDMVQY
                     FRHMHVMKKEDCRTCW"
     aSDomain        11236..11502
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_549_0007"
                     /evalue="4.50E-21"
                     /identifier="TIGR04085"
                     /label="ctg1_549"
                     /locus_tag="ctg1_549"
                     /protein_end="426"
                     /protein_start="337"
                     /score="73.1"
                     /tool="antismash"
                     /translation="CGAGHEYFAITPEGDIYPCHQFVGREKYKMGTLDTGIVKKDMVQY
                     FRHMHVMKKEDCRTCWARFFCSGGCHANADLANGTIEKPYAYGC"
     CDS             17541..18329
                     /NRPS_PKS="Domain: ECH (12-254). E-value: 6.4e-73. Score:
                     236.9. Matches aSDomain: nrpspksdomains_ctg1_550_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 264.3; E-value:
                     1.4e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_550"
                     /transl_table=11
                     /translation="MVNFRNLLLTVQDDGVAVITINRPDILNALDLQTLRELKGCIEEI
                     RRDSRVKAVILQGAGDKAFVAGSDLMAMSRMTAHEAMAFSRFGHEVFNAIENLPMAVIG
                     AIHGYCLGGGLGLALACDFRYASTTAKFGQPEVKYGIIPGFGGSQTLARLIGQGRAKEM
                     IYTGDLIDAQEAYRIGLVNRVLPGEQLMETCEAVCRKIMEKGPIAIGSAKDAINRGLSM
                     DLASGLSYEAQVFGNCFATLDQTEGMKAFLEKRKPVFLGK"
     aSDomain        17577..18302
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_550_ECH.1"
                     /evalue="6.40E-73"
                     /label="ctg1_550_ECH.1"
                     /locus_tag="ctg1_550"
                     /protein_end="254"
                     /protein_start="12"
                     /score="236.9"
                     /tool="antismash"
                     /translation="DDGVAVITINRPDILNALDLQTLRELKGCIEEIRRDSRVKAVILQ
                     GAGDKAFVAGSDLMAMSRMTAHEAMAFSRFGHEVFNAIENLPMAVIGAIHGYCLGGGLG
                     LALACDFRYASTTAKFGQPEVKYGIIPGFGGSQTLARLIGQGRAKEMIYTGDLIDAQEA
                     YRIGLVNRVLPGEQLMETCEAVCRKIMEKGPIAIGSAKDAINRGLSMDLASGLSYEAQV
                     FGNCFATLDQTEGMKAFLEK"
     PFAM_domain     17577..18320
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_550_0016"
                     /evalue="5.00E-74"
                     /label="ctg1_550"
                     /locus_tag="ctg1_550"
                     /protein_end="260"
                     /protein_start="12"
                     /score="248.9"
                     /tool="antismash"
                     /translation="DDGVAVITINRPDILNALDLQTLRELKGCIEEIRRDSRVKAVILQ
                     GAGDKAFVAGSDLMAMSRMTAHEAMAFSRFGHEVFNAIENLPMAVIGAIHGYCLGGGLG
                     LALACDFRYASTTAKFGQPEVKYGIIPGFGGSQTLARLIGQGRAKEMIYTGDLIDAQEA
                     YRIGLVNRVLPGEQLMETCEAVCRKIMEKGPIAIGSAKDAINRGLSMDLASGLSYEAQV
                     FGNCFATLDQTEGMKAFLEKRKPVFL"
     CDS             complement(18537..19055)
                     /locus_tag="ctg1_551"
                     /transl_table=11
                     /translation="MKKSLFFPLLIVSLLSVPSLLFAQEAGSGAEKPAVSVANNTKTAT
                     PSGTVSQEVLPTPPSEDAAAWTLVGGNSSYEVYYDTRSLQYDEKTGIITIWNKWVQKGA
                     VGTGRTILLQSKYDVRLRVVSDLVQYTYNGLGQETGREKVADQSWYPLSPNTLGMELCQ
                     ALKGYLLNQ"
     CDS             19169..20776
                     /locus_tag="ctg1_552"
                     /transl_table=11
                     /translation="MKITFLGADKIVTGSCHLLEVNGKKILLDCGMFQGPKLIRDLNRK
                     PFSFNPGEIDAVILSHAHIDHSGLLPRLIKEGFKGFIHCTPVTEELCQILLPDCGHIQE
                     SDAEIATRKGLRAGKSAVEPLYTADDAYLALKHFITHDYDEDVELYPGITFRFRVAGHI
                     LGSALVNLMIEENGKKTKLIFTGDVGQPNVPILDDPHQISGADFIITESTYGNRIHEQI
                     DREKELCDVMKDALSRGGNVIIPAFAVGRTQVMLYYFQKLMNSGQLPVVPIMVDSPMAI
                     KATQVMLYNPEEYDEEARTIFQKQKGRLIDMPNVKYTETPAESRAINDMPSPMIIISAS
                     GMADAGRVLHHLKHNLWRKDSSVIFAGYQAEGSLGRRLIDGAKKVKIMGEDIVVGAKIY
                     NLSGFSAHADRDQMLALYKGMQQKPKAFFVVHGEYDAASAFAHLLNTELGTATYIPNFG
                     DAAIIDGTDWRIEETRVITSEPAIQNMRDYLRNFEKDYLAYKGRLEQLITHDPRRIPDI
                     RAKMEKIRKYIDDVMKTL"
     PFAM_domain     19205..19765
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_552_0017"
                     /evalue="1.40E-13"
                     /label="ctg1_552"
                     /locus_tag="ctg1_552"
                     /protein_end="199"
                     /protein_start="12"
                     /score="51.4"
                     /tool="antismash"
                     /translation="TGSCHLLEVNGKKILLDCGMFQGPKLIRDLNRKPFSFNPGEIDAV
                     ILSHAHIDHSGLLPRLIKEGFKGFIHCTPVTEELCQILLPDCGHIQESDAEIATRKGLR
                     AGKSAVEPLYTADDAYLALKHFITHDYDEDVELYPGITFRFRVAGHILGSALVNLMIEE
                     NGKKTKLIFTGDVGQPNVPILDDP"
     PFAM_domain     19922..20302
                     /aSDomain="Beta-Casp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10996.10"
                     /description="Beta-Casp domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_552_0018"
                     /evalue="8.30E-26"
                     /label="ctg1_552"
                     /locus_tag="ctg1_552"
                     /protein_end="378"
                     /protein_start="251"
                     /score="90.6"
                     /tool="antismash"
                     /translation="TQVMLYYFQKLMNSGQLPVVPIMVDSPMAIKATQVMLYNPEEYDE
                     EARTIFQKQKGRLIDMPNVKYTETPAESRAINDMPSPMIIISASGMADAGRVLHHLKHN
                     LWRKDSSVIFAGYQAEGSLGRRL"
     PFAM_domain     20342..20533
                     /aSDomain="RMMBL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07521.14"
                     /description="Zn-dependent metallo-hydrolase RNA
                     specificity domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_552_0019"
                     /evalue="1.20E-14"
                     /label="ctg1_552"
                     /locus_tag="ctg1_552"
                     /protein_end="455"
                     /protein_start="391"
                     /score="54.1"
                     /tool="antismash"
                     /translation="IVVGAKIYNLSGFSAHADRDQMLALYKGMQQKPKAFFVVHGEYDA
                     ASAFAHLLNTELGTATYIP"
ORIGIN
        1 tgtaagcgat agaaggagga atgcatgatg atgacggcgg cagcgaccct ggaatcctgg
       61 aaagaaaaac aactgattta aaaaaaagga tactcttttt ctatggcaac gtatcggcaa
      121 taagcattta acattgtgcc aaggatttgg tatgctggaa ccggaagaat cctggaggag
      181 gaattcatga tgacgaagaa actggttgcc tatttttctg ccagcggggt tacagccgcc
      241 aaggcgaaga aactggctga agtggtgggg gcggacctgt acgaaatcgc tcccaaagat
      301 agatatacga acgcggacct gaactggacg aacaaaaagg cccggagcac ggtggaaatg
      361 aacgatcccg ccagccgtcc ggaactgaag gaaaacgggc tggatctgac ggggtatgac
      421 acggtttaca tcggcttccc catctggtgg tacacggcgc cccacatcat ccgcagcttc
      481 ctggaacaga acaagctgac cggcgtggac atcgtattgt tcgccaccag cggcggcagc
      541 agtatttcca aggcgtaccg ggacctgcgc aaggcctacc cgaaactgaa catcacgaac
      601 ggggtgctgc tgaacggctc catttctgga aacctggcgt aagaatagga gatgtggatt
      661 aatttcacag ctccgttttc ggcatttttg aaaaggagga tcccttatgg accgcagaga
      721 atttttgaag atctccggac tgggggcact ggccctggtc ctgagtagct gtggcttttc
      781 aaaacagacg gcttcttcgg cacagctgac gggaggcggc agctccgcca ccggcaagga
      841 aaaagtggcc ggtacgggcg gtgacaaata catcccgccg gaacaacggc agggcaatga
      901 atccgtggtg tacttcaccc gggacttgtc agcggctggc ctgctgaaga tttatgagac
      961 cattgccggc aacatgaccg gcagggtggg catcaagctg catacgggcg agccccatgg
     1021 ccccaacatc attccccggc cctgggtgaa gcagctcatg gaagcgaagc tgcccaatgc
     1081 cagaatcgtg gagacgaata cctattacgg cggagcccgg tacaccacgg aagaacaccg
     1141 gaagaccctg gccgtgaacg gctgggattt cgcgccggtg gatatcctgg acgaagaggg
     1201 gaccaccatg ctgcccgtca agggaggcaa atggttcacg gagatgtccg tgggttccca
     1261 tctgctgaac tacgattccc tgctggtgct gacccatttc aagggccata ccatgggcgg
     1321 cttcggcggc tccgacaaga atatcggcat cggttgtgcc gacggccgca tcggcaagaa
     1381 gatgatccat tccggcgagg gcggcagcca gtggggcatc gataaggaag aattcatgga
     1441 acggctgacg gaatcatcca aggccacggc ggaccatttc ggcaatcaca tcgcctacat
     1501 caatgtgctg cgcaacatgt ccgtatcctg cgactgcgaa gggaccgggg cccagcccgt
     1561 ggtgacgccc aacatcggta tcctggcgtc cacggacatc ctggcggccg atcaggcttc
     1621 cgtagacctg gtctatgccc tgccggaaaa agatcgccac gccctggtgg aacggatgga
     1681 aagccgccac ggcctgcgcc agctgagcta catgaaggaa ctgggcatgg gctgcgaccg
     1741 gtatgtgctg ctggacctgg accatggcag ccagcccctg accctggcgg atgcggtgaa
     1801 ggacgtgaag ccctttgagg ggtaaaacag ctgataagag gtatgatttt tcacatcccc
     1861 ctttttccat acgtttttcc tatttccatg gatgaacgat aagcatttaa catggctctc
     1921 cagatttgct atgatacacc caagagagaa cccgaaggag gaatcatgat ggacgaacgc
     1981 ttgaaacaat ttgctggctt cgcgctggcc ctggtcatga cgacttgcat gggcatacat
     2041 tatggggagg cagcagtcat ggaaaatgaa acgaagaaac cggtcaaaat cgtgcaaacc
     2101 gcaggcagag acgtgctggg ggaattcgcc ccggaatttg cccgctacaa cgatgacatc
     2161 ctgttcggtg aagtgtggag cgccaatgac aaactgagcc tgcacgaccg cagcatcgtt
     2221 accgtatccg ctctgatctc tcagggcatc acggacagtt ctctgaaata ccacattacg
     2281 tccgccagga acaacggcgt gaccaaggaa gaaatggtcc agatcatcac acagctgggc
     2341 ttctacgccg gctggcccaa agcctgggca gcattccggc tggccaagga agtgtacgaa
     2401 gcttgaggca gtcactagtc tctagtcact agtcaccagc cgaaggagaa aatttgccac
     2461 aggcaaattt tgaagaaaag aacaagatca agatgaggta acaggtatgg acgagaaact
     2521 tcgtgagaat ctggaggctg ccgggtgccc ggatgaggtc atccggaaag tccagcagat
     2581 ggaggggaca cagcagcaga ccctggagct gcggaaatac cggcgctgcc tgctggaaaa
     2641 ggtgcaccgg gaacaggaac ggctgacgaa cctggattat ctgctgtacc agttggagaa
     2701 gcaagcttga aacagtctcg agtcagtagt cactagtctc tagccaaagg aaagaacctg
     2761 ccctggaaac aggacaggtt cttttgatat tatttttctg gattgacttt ctccttcagt
     2821 cgttccagga atacctggct ggaatggctg agcaggcggt actttttcca ggccaccagg
     2881 ctggagactt cgtaggccgg ctccagaggg atgaatttca attccgggga ttcgtggtgc
     2941 tccagccggt ccaggcacag caagttggcc acctgctgga agaccagggg attggtgttg
     3001 caggaaaggt ccatggtgcc cacgatgttc agcttctcta cagagatctt gcccttggac
     3061 cagccttcta ggtcgaagga ccggttgttg tgccgggagg aggtcatgag ggggattccc
     3121 agaatgtttt ccggggtgac ggcatccagc tttgcccagg ggctgtggat gctggtgacg
     3181 atgcccagcc ggttcttgcc cggcagctcc agataattgt agttttccac gttgaagggc
     3241 tggatgaaca ggccgaaatc cagcaggccg tgttccagct tttcctggat gatatcggcg
     3301 ttgccggtga gcatttcgat ggtcaggtgg ggattctcct tgcgcaggtc ggcgaaggta
     3361 tccgtcagat agtggaccag ataggtgatg ccggccccga tgcggatgca gccggtcagg
     3421 ttcagatctt catccttaat ctcgcttttc gtctgttcca ccagggccag gatttcttcg
     3481 gcccgctggc gtaggtgcat cccttcttcg gtgagggtgg tgctgcggtt gctgcggatg
     3541 aacagtttct tgcccagttc cttttccagg tcggccatct ggcgggacag ggtaggctgg
     3601 gtgacgaaca gcaaattggc agcttcggtc atgttctgtt cccgggccac cgccaggaaa
     3661 tatttcaggg tgcggatttc cataaggacg ctcctttcac tgggcatgta tggcaagcaa
     3721 gatattatgc aaaatattta taccataaga ataataagaa atcgtaggaa tgtcaatatt
     3781 tggaggtgtg gacaaggccg gcagttaggc tttataataa atatatctaa ctgacgcatc
     3841 gaaaggacgg gtgggcattg tggatctggt ggacaagctg aaggaatatt ccgtactcac
     3901 ggacgaggag tataaggccc tgctccagac ggaggaccct ctgctgcggg ataaactgtt
     3961 ccggggcgtc caggaggcca tgaactatgt gttccaccgc agggtgtact tccagggcgt
     4021 gctggaattc agcaaccacg gttctataat aaatgttggg gtcttgtgga cactcctgtt
     4081 cacaagaccc cttgtcttac ggtaaaataa agacatatct aagctacatt tcacctcaac
     4141 caccacgaag aactgaaagg agaatagata tgtctttctt tcattttatc gaaaaaagct
     4201 tccattggga agagggttcc ataaaagaat ttgaaaaatt gggatccagc cacctccttt
     4261 acgtggaatt cacttctaca gcttctcgtt gcccctactg tcatcataaa attctccata
     4321 gtaaggacta tcgggaccca aaagtcctct tagggcactg gaacacccat cctgtttctg
     4381 ctattgttca taaaagaaga tttttttgcc cttgctgcca taagacattt tatgaaaaaa
     4441 ttcctggcgt cgagcattac cagcggcgtt ctaacgatat aaagaacagt atcatccaag
     4501 cctgttctga actggcgagc tttaaagcca ttgccagaag ccatggtgtc tctgtttcca
     4561 ccgtaagaat tacagagagc ctatgcctta aaagaggcat tctttaaggt attttctatg
     4621 aaagaacggt ctgctgttgc ttcattctta tctcgttggt tatcattagt cgaagaaagt
     4681 ggggttgaag aattcaagag tgttataaag acgttcactg attggaagac agagattttg
     4741 gaaggattga gtcaagcgta ttcgaatggt tttacggaag gaatgaacaa taagattaag
     4801 gtgttaaaga gagtagcatt tggttttcgc aactttgaac gattccgttc tcggatttta
     4861 ctgctttcga tggtgaaatt aaaataaaaa cagacgtgag caaaaatcgc tcacgtccgt
     4921 atgtggtaga tgaattggag cttaccccaa catttgacaa agaacccttt tttgttggaa
     4981 aacccgaagg aggaaaatgc atgtccctga agatgattgc catggatctg gatggcaccc
     5041 tgctggatga agaaaagaat attgctccgg aagatgcggc tgcagtcaag gatgcagtgg
     5101 ctgccggata ctatgtgacc ctggccaccg gccggatgta ccggtcggcc ctgccttacg
     5161 ctcaggaact gaggctgacc catcccctgg tggtctacaa cggagccctg atccgggatc
     5221 ccggaaccgg agagaacctg ggccagtggc ccctgcccct ggatgtggcc cagtccgtgc
     5281 tggatgacct gctgggatgg ggcatctatg tccaggccta tgtggatgac accctgtggg
     5341 ctccccggga ctgtgaggaa gtccggttct attcccggtt ttcccgggtg ccttatgaag
     5401 taaagacgga agccatccgt catctgcccc aggctcccca caaactgctg gtgatttccg
     5461 atcaggtcag gaccctgcgg ccggaactgg aagagaagta tagagggaag atcaaaatcg
     5521 tcagctcttc caaagggttc ctggaagtga cggcccccgg caccaacaaa tggcatgccc
     5581 tccaggccct ggctgcccgg gaaggcatcc gggaagaaga aatcctctgt gtgggggatt
     5641 cggacaatga tctggaaatg atttcccacg ccggtttcgg ggtggccatg ggcaacgcca
     5701 gcgatccggt gcgggaggcg gcccgggtgg tgacggcgcc caatacccgg aacggagtgg
     5761 cccggatcat ccggaccatc ctgacccggc aggtggaagt gcccgtctga aggaatgcac
     5821 cgggacttta cacagacttt ttttccattg tataataaaa acgttctata cttttcaggg
     5881 ggtggatgca aatggcgaga acgttactga ttacagggat gtccggggcg gggaagacgc
     5941 aggtcatgcg gaccctggaa gatctgggct atttttgcgt ggacaatctt cctcctacct
     6001 ttattcccaa attcattgaa ctgtgcctgc agaacaagaa cggcggggct cagctggctc
     6061 tggtggtgga tatccggggc ggcaaattct tcaaggatct gaaccgggtc ctggaccagc
     6121 tgaaccagag cagcgtacct tacgaactgg tcttcctgga tgcggatgat gccaccctga
     6181 tccgtcggta caaggaaacc cgccggcgcc acccgctggc ggggaaaaac gggctcagtg
     6241 cggatattgc ccgggaacgg gacatcctga gccagatccg gcagagggcc accaccatca
     6301 tcgacacctc ccggaccacc accaaggaat tgcggcagaa aattgtccag ctcttcggca
     6361 agggcggcga actgcccccc atgaacattg tggtccagtc tttcgggttc aaatatggga
     6421 tccccctgga ttgcgacatg gtctttgatg tgcggttcct gcccaatcct ttctacatcc
     6481 cggaactgaa aaacctgtgc ggcaacgacc agccggtgat ggactacatc caggaaaagc
     6541 cggtgacagg ggaattcgag gagaagctgt tcagcctgat ccagttcctg ctgccccagt
     6601 atgtccagga agggaaaagc cagctgatga tcggcgtggg ctgcaccggc ggccggcacc
     6661 ggagtgtgtt cattgccaat gccctgggcc ggttcattga aaaatgcggg tacggggtgc
     6721 aggtcatcca tagggatttg ataaagaaat aggtgaatgc gtatgaaatg gattaagtgg
     6781 ttgtacccgg ggctgaacct gaagcgctgg ctctttcttt ttgcgctggg cgcggtactg
     6841 gcctgtgtgg gagtcacttt aatcttcaat tatcagtttg tagggctcct ggaagccctg
     6901 gtgctgcagt tcatcagttc cgtgggagga gagtattacc agtccaccat taccgggctg
     6961 ggagccttca gtgtggtcct ggggatcctg tgcatgtgcc tgggggccac ccatgtgatc
     7021 aagaccatta tcaatgcggt gatgcccgga gaaaaggaat cccttcggga gctgatcttt
     7081 acccagcaga agctggacaa gggacccagc gtggtggtca tcggcggcgg gacgggactt
     7141 tccgtactgc tccggggcat caagctcatt accaacaact gtacggctgt ggtgaccacc
     7201 gcagacgacg gcggatcttc cggacggctg cggaaagaac tgggaatcct gcctcccggg
     7261 gatatgcgga actgcctggt ggccctgtcc gatacggaac cgctgatgga aaaagtcatg
     7321 cagtaccggt tcaaaagcag tgccctcagc ggccataacc tgggcaacct gttcattgcc
     7381 gccatgagtg atgtggaagg cggggacatg gaaaagggca tcgctgccac ctgcgagatc
     7441 ctgaaagtgc ggggccatgt atggccaaac accacggaca atatccagct gaaggccaaa
     7501 atggacgacg gcagcaccgt ggtgggggaa agctccatta ccgcttcgcc ccataaaatc
     7561 gtccagctga tgacggaacc ggaaaatccc cgggcgtccc agcgggccgt ggatgccatc
     7621 ctgaaggccg atgccatcat cctggggccc ggcagcctgt ataccagcgt gctggccagt
     7681 ctgatcgtgc ccggcatccg ggatgcagtg atccggtcca aggccgtgaa gatctacgtg
     7741 tgcaatgtga tgacccagcc cggggaaacc gatggctatg gggcctatga gcatgtgagg
     7801 gccctgatcc ggcacatggg ctgtcagtgc ctggactatg tggtggtcaa cgagcagaag
     7861 gcctctccgg atatcctggc caagtacgaa aaagaagggg ccatgcccgt ttctccggat
     7921 gtggagaaaa tcgaacagct gggaatcgac tgtgtaccgg ccaaactgct gaatgacagc
     7981 gacctggtcc ggcacaatcc cctgaagctg gccaagacca tcattgccct gatttaccgg
     8041 ctgaagctgt tcggcaaggg catccggttc ttcgactatt tcttcgcccg gcagaccatg
     8101 caggaactgc ggaagcatgc caggaaggag cactgaccat gtccttttcc catgatgtga
     8161 aaaatgaaat cgcacggtca gaaggggaga accatgactg tgaaaaagcg gagctgttcg
     8221 ggctgctgcg gatcagcggg gcggtttccc tcagcggacg gaaagtgggg atccatttca
     8281 ccacggaaaa cgcggccctg gcaagacggg tgctgcggct gctgaaaaac aattttcccg
     8341 tgcagacgga agtcatcgtc acccggagcc gccgtctgaa aaagaacaat cggtaccagg
     8401 tccatgtgat cccttccgat gaggcaagga ctgccctgag ccggctccat ctcctttctc
     8461 ctctggagga ggcgggcagc gccctgctga aaaaagaagg ggaaaagaga gcctttctcc
     8521 ggggggtatt cctggccggg ggctcggtga acaagcccat cagcgattac catctggaac
     8581 tgatctgtga cagcctggac atggggcagt ttatccagaa aatcatgaag ggcttcagcc
     8641 ttccggcccg gatcgtggac cggaaaaact cctatatcgt atatctgaag gaaggcaacg
     8701 ccattgccgg gttcctgtcc ctgatcggag ccagcaattc ctacctggaa tttgaaaatg
     8761 tccgggtgct gaaagatatg cggaacaagg tgaaccggca ggtcaactgt gaaaccgcca
     8821 acctgaacaa ggtggtccag gcggcggtgc ggcagctgaa tgccatacgg gtcattgaag
     8881 aaacagtggg gctcagcacc ctgccggaac cgctccagga ggcagccaga ctccggagag
     8941 accatcagga cctgtctgtg ggagaactgg cggccctgac agaagacaat gtgggaaaat
     9001 ccggcttcaa tcaccggttg aagaaactgg aacagctggc ggaaaaactg aaggatgggg
     9061 agcaatgaaa aaactgatta ttttcttggc gattgtggca gctctggccg ggtttgccta
     9121 tgggggctat gaatatgtaa aacgggattt tccccgtttc tgtgaggaaa ccgtgccgat
     9181 ctttgcctac catcgggtag agccggggca tgatgaccct tataccatgc ctccggaaca
     9241 gttcgatgag cagatgaaat atctgaaaga acagggctgg aagaccatga ccctggcgga
     9301 atatgtcaag ggccggaagg aaggacggaa gtttcacaag gaatgtgtcc tgatctttga
     9361 tgacggctac ctggacaacc tgacctatgc ggcccccatc ctgaaaaaat acggctttgt
     9421 ggggaacatg tacatggccg tgaagtatga aggctggccc ggctatctgg actggaacca
     9481 ggaacatgaa ctgctgaagt acggctgggc cctggggtcc cataccttca accacaagcc
     9541 cctccagtcc ctgacaccgg aacaggtgga ctatgaactg accagctcca tgcagcatat
     9601 gcggggcatc tacaatccgc cggaaggact caccttctcc tatcccaacg gatctgccag
     9661 cgacgccatt gcggcccagg taaaaaaagc cggctatatt gccggggtgg acggccgtgt
     9721 gggggtgaac acggacaaag tggatctgat gcggctgcgc cgggtaaatg tgttccagaa
     9781 caaaccggaa aacctgggct gcttccagta tgatctgaaa cgggcccaga tccagagcta
     9841 catcgaccag accggattgg atacggactg gctcatccac aaatattacg aactgaaagg
     9901 caaactccat ctgtaagaaa gatagaaacg gttgaaagac ttgcgttctt tctgaaaaac
     9961 agataaaatg gatagtaaac aagaagatag ggaggaatcg atgatggcaa aaagaatcaa
    10021 gactgtgaat aaagaaatgc tgaaaaagac cctgagaacc ggcggctgcg gcgaatgccc
    10081 ggcatcctgc cagtctgcct gcaaaacttc ctgcacggta ggcaaccagg tttgcgaaaa
    10141 agcataattt atattatgcg cggaagctcc ctgcatgcgc agggagctat tttcttgtaa
    10201 tcaataagaa gggcggacag aaatttgatc catagaatgc atctggacga caattacgtg
    10261 gtccttgacg tgaacagcgg cgccgtgcac attatcgacg ccatgattta tgatattctg
    10321 ggcttttacg acggcaccaa cgccgaagcg accaaagccc attttgccgg caaatacccg
    10381 gcggaagacg tggctgaagc cctggacgaa ctccaggaac tgcagaaggc cggtctgctg
    10441 ttttctccgg actttccggt gccggatacc ttttccgatg aaccggtgct gaaatccctg
    10501 tgcctccatg tggcccacga ctgcaacctg cggtgcggct actgctttgc agataccggg
    10561 gacttcgggg gccatcgggc tctcatgagc aaggaagtgg cccggaaggc catcgaattt
    10621 gccattgccg gcagcaaaca gcggcacaac ctggaactgg acctgttcgg cggagaacct
    10681 ctgatgaaca tgcccgtggt gaagtacatt gtggactatg tgcgccagcg ggaaaaagaa
    10741 accgggaaga acatcaaact gaccctgacc accaacggca ccctgctcac cgatgaaatc
    10801 gtgaagtatc tcaacgacaa ccgggtgatg ctggtgcttt ccctggacgg cagcaaaaag
    10861 acccatgaca acatgcgtcc ctatccgggc catgtagggt cctatgatgc agctgtgaaa
    10921 ggcttccgga aggtcatcga atcccgtcac ggaaagaact actacctgcg gggcacctat
    10981 acccattaca acacccattt ctgcgatgac gtattggcca tgctggacgt gggatccgaa
    11041 atttccatgg aaccggtggt gggcaccacg gaaccctggg tgctgacgga agaagactgg
    11101 cccaccctgg acaaggaata cgagaaactg gcccgggcct atctggccag gaaaagggcg
    11161 ggagaagctt ttgacttctt ccacttcaac gtggccctgg acaacggtcc ctgcgtggcc
    11221 aaacgactgg caggctgcgg tgccggtcat gaatatttcg ccattactcc cgaaggggac
    11281 atttatccct gccatcagtt tgtgggccgg gaaaaataca agatggggac cctggatacg
    11341 ggcattgtga aaaaggacat ggtccagtat ttccgtcaca tgcacgtgat gaaaaaagaa
    11401 gactgccgga cctgctgggc acggttcttc tgcagcggcg gctgccatgc caatgcggat
    11461 ctggccaatg gcaccattga aaaaccctat gcctacgggt gccggatcca gaagaaacgg
    11521 ctggaaatgg ccatcatcct ccaggctctg ctgacagagg acgtgaagga aggcggggca
    11581 gaccaccgtc ccgtcatcga caacttcaaa ttccaggtgg agaagaagta aatcagcttg
    11641 tcaacggtca gttgtctacg gtcagcggcc gcaggaaggg attggcaaag gagcctttgc
    11701 caatcccttc caattttttt agaaaacata gttgacaaaa atctactccc gtgatattat
    11761 aatcaagccg ccgatgagcg acaaggttag aaccctgaaa actgaatatt gttgacagat
    11821 gtgcgggtca agtcaccttt acggtgatga gatcgagtca cctggatgac aaccaggtta
    11881 aaaaatcaaa gctagttttt caagagccaa gcggctcttc aaaatactct attttggaga
    11941 gtttgatcct ggctcaggac gaacgctggc ggcgtgctta acacatgcaa gtcgaacgga
    12001 gaactttctt cggaatgttc ttagtggcga acgggtgagt aacgcgtagg caacctgccc
    12061 tctggttggg gacaacattc cgaaagggat gctaataccg aatgagatcc tctttccgca
    12121 tggagagagg atgaaagatg gcctctactt gtaagctatc gccagaagat gggcctgcgt
    12181 ctgattagct tgtaggtgag gtaacggctc acctaggcga tgatcagtag ccggtctgag
    12241 aggatgaacg gccacattgg gactgagaca cggcccaaac tcctacggga ggcagcagtg
    12301 gggaatcttc cgcaatggac gaaagtctga cggagcaacg ccgcgtgagt gatgaaggcc
    12361 ttcgggttgt aaaactctgt tgtcagggac gaaagcaccg atctataata cattttggtg
    12421 ttgacggtac ctgacgagga agccacggct aactacgtgc cagcagccgc ggtaatacgt
    12481 aggtggcaag cgttgtccgg aattattggg cgtaaagagc atgtaggcgg gcttttaagt
    12541 ccgacgtgaa aatgcggggc ttaaccccgt atggcgttgg atactggaag tcttgagtgc
    12601 aggagaggaa aggggaattc ccagtgtagc ggtgaaatgc gtagatattg ggaggaacac
    12661 cagtggcgaa ggcgcctttc tggactgtgt ctgacgctga gatgcgaaag ccagggtagc
    12721 aaacgggatt agataccccg gtagtcctgg ccgtaaacga tgggtactag gtgtaggagg
    12781 tatcgacccc ttctgtgccg gagttaacgc aataagtacc ccgcctgggg actacgatcg
    12841 caagattgaa actcaaagga attgacgggg gcccgcacaa gcggtggagt atgtggttta
    12901 attcgacgca acgcgaagaa ccttaccaag gcttgacatt gagtgaaaga cccagagatg
    12961 ggttcccttc ttcggaagca cgaaaacagg tggtgcatgg ctgtcgtcag ctcgtgtcgt
    13021 gagatgttgg gttaagtccc gcaacgagcg caacccttat cctatgttac cagcacgcaa
    13081 tggtggggac tcataggaga ctgccaggga taacctggag gaaggcgggg atgacgtcaa
    13141 gtcatcatgc cccttatgtc ttgggctaca cacgtactac aatggtcggc aacaaagggc
    13201 agcgaagccg cgaggcggag ccaatcccag aaacccgacc ccagttcgga tcgcaggctg
    13261 caacccgcct gcgtgaagtt ggaatcgcta gtaatcgcag gtcagcatac tgcggtgaat
    13321 acgttcccgg gccttgtaca caccgcccgt cacaccacga aagttggtaa cacccgaagc
    13381 cggtgagata accttttagg agtcagctgt ctaaggtggg gccgatgatt ggggtgaagt
    13441 cgtaacaagg tagccgttcg agaacgagcg gctggatcac ctcctttcta tggagaaccg
    13501 aaggagtcca aggactcact tctattctcg tcgacgcaca tctgtcaaaa caatatttgg
    13561 ttttgagggt tttaccctca ggcaatccat gggcctatag ctcagctggt tagagcgcac
    13621 gcctgataag cgtgaggtca gaggtccgag tcctcttagg cccaccaatt tttgaattga
    13681 aatggattgt tgaaatagtt ttcatctgtt cttctgaaca gctgaaatat agcgggggcg
    13741 tagctcagct gggagagcac ctgccttgca agcagggggt caggagttcg attctcctcg
    13801 tctccaccac atgaaccttg aaaacttcat agaagagaca aaacaaagtc ttggacattg
    13861 tgatgaatgt ctaagcacct ctgatctaaa tgcgaattta gaaacgagta acgagaatac
    13921 cagggaacgt aagttcctta gtaaactgaa ccagaaaatt gcaaagagaa attgctctga
    13981 tccgcgaagc gaggaagaga gccatcggag actatactcc agtatgtcga gggtggcgaa
    14041 cgacgagcga caaaggagcg gacaatttat cgaagcaatt ttaagtcaag ctactaaggg
    14101 catacggtga atgccttggc actaagagcc gatgaaggac gtggtaagct gcgaaaagct
    14161 acggggagcc gcaagcaggc tttgatccgt aggtgtccga atgggggaac ccaccatccg
    14221 tcatgggatg gtatccttcg ggaagggaac ccggtgaact gaaacatcta agtagccgga
    14281 ggaagagaaa tcaaacgaga tgcccacagt agcggcgagc gaagagggca gagcctaaac
    14341 cagagagctt cggctccctg gggttacgga ctggcataag cgaagtccaa tctagtcgaa
    14401 tcacctggaa aggtgagcca cagaccgtga gagccgggta gattaaagat tgaatgagtg
    14461 gccagtatcc agagtaccgc gaagcacgag gaattttgcg ggaagtcggg gggaccaccc
    14521 tccaaggcta aacacttctt agtgaccgat agcgcatagt accgtgaggg aaaggtgaaa
    14581 agaaccgcgg gagcggagtg aaagagaacc tgaaaccgta tgtctacaag cagtcggagc
    14641 gcaagcgacg gcgtgcctat tgaagaatga gccaacgagt tacgggcgcc agcgaggtta
    14701 agcaggaaat gcggagccgt agggaaaccg agtctgaaaa gggcggatag ttggtgttcg
    14761 tagacccgaa actgtagtga tctacccatg atcaggttga agcacgggta aaatcgtgtg
    14821 gaggaccgaa ccggtgagtg ttgaaaaact ttcggatgaa tcgtgggtag cggtgaaatt
    14881 ccaatcgaac gcagagatag ctggttctcc tcgaaatagc tttagggcta gcctcaggca
    14941 gtaagcatag gcggtagagc actgatcggg atagggactg taatggttac cgaaccctgt
    15001 caaactacga atggttatgc tgcagagcct gggagtcaga ctacgagaga taagtcccgt
    15061 tgtcaaaagg gaaacagccc agaccatcag ctaaggtccc caatgccata ctaagtggaa
    15121 aaggatgtgg ggtctcataa acaaccagga tgttggctca gaagcagcca ccatttaaag
    15181 agtgcgtaat agctcactgg tcgagaggcc ctgcgccgaa gattcccggg gctaaagtat
    15241 ggaaccgaag ctatggatgc atacgtaggt atgcgtggta gaggagcgtt cccatcgggt
    15301 tgaagtcgtc ctggaaggga cggtggactg gtgggaagtg agaatgttgg catgagtagc
    15361 gaaaagaatg gtgagaatcc attccaccga aagcataagg attcctgagc aacgatcgtc
    15421 gtctcagggt aagtcgggac ctaatccgag gcaaagagcg taggagatgg acaactggtt
    15481 gatattccag taccggcagt gatcgtttga acgaaggagt gacgcaggaa ggcaggtccg
    15541 cacgagattg gtagatcgtg tgcaagcgtg taggctggtt accaggcaaa tccggtaact
    15601 gaggctgagg cgtgatgcgg agggaacttg ttcccgaagg gattgagcct acgctgccga
    15661 gaaaagcttc tagtgagaaa gctgccgccc gtaccgtaaa ccgacacagg tatgcgggga
    15721 gagaatccta aggtgcgcgg gagaaccctc gttaaggaac tcggcaaaat gtacccgtaa
    15781 cttcgggata agggtagcca caaaggtgaa gggacttgct cccggagccc ggtgtggtcg
    15841 cagagaagag gcccaagcga ctgttaacca gaaacacagg tgcctgcgaa agagaaatct
    15901 gaagtatagg tgctgacacc tgcccagtgc tggaaggtta aagaaggatg tccgggttcg
    15961 acccaaagca ttcgactgaa gccccagtga acggcggccg taactataac ggtcctaagg
    16021 tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggtgtaacg atttgggcac
    16081 tgtctcaacg agggacccgg tgaaattgaa atacctgtga agatgcaggt tacccgcgac
    16141 tggacagaaa gaccccatgg agctttactg taacctaata ttgggttctg atacttgatg
    16201 cacaggatag gtgggaggca tggaaggcag tcctctggga ttgccggagc cgacgttggg
    16261 ataccaccct tcaattatcg ggattctaac cgagcgagta acgatcgccg ggacagtgtt
    16321 aggcgggcag tttgactggg gcggtcgcct cccaaagagt aacggaggcg cccaaaggtt
    16381 ccctcagcgc ggacggaaac cgcgcgcgga gtgtaaagac agaagggagc ttgactgcga
    16441 gccaaacacg gcgagcaggt acgaaagtag ggcttagtga tccggtggca tccaagtgga
    16501 agggccatcg ctcaacggat aaaagctacc ctggggataa caggctaatc tctcccaaga
    16561 gtccatatcg acggggaggt ttggcacctc gatgtcggct catcacatcc tggggctgaa
    16621 gtcggtccca agggctgggc tgttcgccca ttaaagtggt acgtgagctg ggttcagaac
    16681 gtcgtgagac agttcggtcc ctatccatcg cgggcgcaag agatttgaag ggggctgctc
    16741 ctagtacgag aggaccggag tggacggacc gctggtgtac caattatccc gccaggggta
    16801 cagttgggta gctacgtccg gaacggataa acgctgaaag catctaagcg tgaaaccatc
    16861 cttaagatga gatctctcac agcgtaagct ggtaagacac ctggaagatt accaggttga
    16921 taggcagggt gtggaagcgt agtaatatgt taagctgacc tgtactaata tgtcgagggc
    16981 ttgacttaag tgagtcgcct accgcgaagc ggctgaggca tacgaaataa aagagcaagt
    17041 gagcgaaaga agctcgtaac gttacgtccg aaagaacgta tatgtctctt catgaagttt
    17101 tgagggctca tgccttcagt aacataatcc ggtggcgata gctaagggga tccacctgtt
    17161 cccatgccga acacagcagt taagccctta tacgccgaaa gtactcgact ggaaacggtc
    17221 cgggaggata gggagctgcc ggttaagaaa attccgcatc tgatggatgc ggaatttttt
    17281 gtcaacggtc agctgtcact cggacccgta ggggctgcac gccgggcagc ccgtctggat
    17341 gccgattgcc gatgcacagg gcggggcacc gggcctgcgc ctcctacgga tcagggcact
    17401 tcaaaatcaa ccggaaccgc aggggctgtt gaccgttgac cgctgaccgg ggctgtgaat
    17461 tcccctccct ctttcccctt gccaaaaccg gctttaataa gatacaatat tctaaaaaat
    17521 ccaactttta ggaggcgact atggttaact tcagaaatct tttgctgacg gtccaggatg
    17581 acggggtggc tgtcatcacc atcaaccgtc cggacatcct caacgcgctg gatctccaaa
    17641 ccctgcggga gctgaaaggg tgcatcgaag aaatccgacg ggattcccgg gtaaaggcag
    17701 tgatcctcca gggggccggg gacaaggcct ttgtggccgg gtcggatctg atggccatga
    17761 gccggatgac ggcccatgag gccatggctt tttcccggtt cggccatgaa gtgttcaatg
    17821 ccatcgaaaa tctgcccatg gccgttatcg gggccatcca cgggtattgt ctgggtgggg
    17881 gcctgggact ggccctggcc tgtgatttcc ggtatgcgtc caccacggcc aaattcggac
    17941 agccggaagt gaagtacggg atcatccccg gttttggggg ttcccagacc ctggcccggc
    18001 tcatcgggca gggacgggcc aaggaaatga tctataccgg ggatctgatt gatgcccagg
    18061 aggcttaccg gatcggtctg gtgaaccggg tgctgccggg agaacagctg atggaaacct
    18121 gtgaagccgt gtgccggaag atcatggaaa aggggcccat tgccatcggc tccgccaagg
    18181 atgccatcaa ccggggcctg tccatggacc tggcttccgg tctcagctac gaggcccagg
    18241 ttttcggcaa ctgcttcgcc accctggacc agacagaagg gatgaaagcg tttttggaaa
    18301 aacgtaaacc ggtgttttta gggaaatgaa agaggggctg ttgcataggc aacagctccg
    18361 tcaactggca gttgactatg tgtgctgcgg ggcgccgggc ctgcgccccc tacggtttct
    18421 actgttcaaa atcaatttgt aaaattgatt tccaacggct gctgacagct gaccgttgac
    18481 agctgaccgt tgacagaaaa gggagtgctg cacagaacgt gcagcacccc cttttttcac
    18541 tgattcagca gatacccttt cagcgcctgg cacagttcca tgcccagggt gttggggctc
    18601 aggggatacc aggactggtc agccactttt tcccgtcccg tttcctgtcc cagcccgttg
    18661 taggtgtact ggaccagatc ggacaccacc cgcagacgca catcgtattt actttgaagc
    18721 aggatggttc ttcccgtgcc cacggctccc ttctgcaccc atttgttcca gatggtgatg
    18781 atcccggtct tttcgtcgta ctggaggctc cgggtatcgt aatacacctc atagctgctg
    18841 ttgccgccca ctagggtcca ggcagccgca tcttccgagg gaggagtggg gaggacctcc
    18901 tgggaaacag tcccagaggg tgtagcggtt tttgtattat ttgcaacaga aactgccggt
    18961 ttttccgcac cggacccggc ttcctgagca aaaagcaggg atggcaccga cagcagagaa
    19021 acaatcaata gaggaaaaaa tagagacttt ttcataacgt acaccctttc tggtcaatcc
    19081 atggaactat tgtaccacat cgtgccgtac tataggtact ttccctgaaa gagtcaggca
    19141 aaaacttttg aacaaggagg gatccttcat gaaaatcacc ttcctgggcg cggataaaat
    19201 cgttaccggg tcctgtcacc tgctggaagt caacggaaaa aagatcctgc tggactgcgg
    19261 aatgttccag ggccccaaac tgatccggga cctgaaccgc aagccttttt ccttcaatcc
    19321 gggcgaaatt gacgcggtga tcctgagcca tgcccatatc gaccacagcg gcctgctgcc
    19381 ccggctgatc aaggaagggt tcaagggctt catccactgc acgccggtta ccgaagaatt
    19441 gtgtcagatc ctgctgccgg actgcgggca catccaggaa tccgatgcgg aaatcgccac
    19501 ccggaaaggg ctccgggccg ggaaatctgc cgtggaaccc ctgtatacgg cggatgatgc
    19561 ctatctggcc ctgaagcatt tcattaccca cgactatgat gaagatgtgg aactgtaccc
    19621 ggggatcacc ttccgcttcc gggtggccgg ccatatcctg ggcagcgccc tggtgaacct
    19681 gatgattgaa gaaaacggga agaagaccaa gctgatcttc accggggatg tgggccagcc
    19741 caatgtaccc atcctggatg atccccatca gatttccggt gcggatttca tcatcaccga
    19801 atccacctac gggaaccgga tccatgaaca gatcgaccgg gaaaaggaac tgtgtgatgt
    19861 gatgaaggac gccctgagcc gggggggcaa cgtgatcatc cccgcttttg ccgtagggcg
    19921 tacccaggtg atgctctact acttccagaa gctcatgaac agcggccagc tgccggtggt
    19981 ccccattatg gtggacagcc ccatggccat caaggccacc caggtgatgc tgtacaatcc
    20041 ggaggaatat gatgaggaag cccggaccat cttccagaaa cagaagggcc gtctcatcga
    20101 catgcccaat gtgaaataca cggaaacccc ggcggaatcc cgggccatca acgacatgcc
    20161 cagccccatg atcatcatct ccgccagcgg catggccgat gccggccggg tgctccacca
    20221 tctgaaacac aacctgtggc ggaaggacag ctcggtgatc ttcgccgggt atcaggcgga
    20281 aggcagcctg ggccgccggc tcatcgacgg ggccaaaaaa gtcaagatca tgggcgaaga
    20341 cattgtggtg ggcgccaaga tctacaacct gtccggtttc tccgcccatg cggaccggga
    20401 tcagatgctg gccctgtaca aggggatgca gcagaagccc aaagccttct tcgtggtcca
    20461 tggggaatac gatgcggcca gcgcctttgc ccatctgctg aacacggaac tgggcactgc
    20521 cacctacatc cccaacttcg gagatgcggc catcatcgac ggcactgact ggcggattga
    20581 ggaaaccagg gtgatcacca gcgaaccggc catccagaac atgcgggatt atctgcggaa
    20641 ctttgaaaag gattacctgg cctacaaggg ccgtctggaa cagctcatta cccatgatcc
    20701 ccggcggatt cccgatatcc gggccaagat ggaaaaaatc cgcaaataca ttgacgatgt
    20761 gatgaaaact ctctgacaga tatttgacat ctgaaaggga aaagaatata ataggaaagt
    20821 cgaaatgatg cagtttactt tgaggatgct tcctgacaag catcctcttg atttatctgg
    20881 aaataagagg ggattgggct tttatgatta gaaacgattt gcgtaacatt gccatcatcg
    20941 ctcacgtcga ccacggtaag actaccctgg tggacgccat gctgaaacag agcggtgtat
    21001 tccgtgccaa ccagcaggtg caggaacggg tcatggactc caacgatcag gaaagagaac
    21061 gtggaatcac catcctggcc aagaacactt ccgttatgca tgatggctgc aaaatcaaca
    21121 tcctggatac tccgggccac gccgatttcg gcggcgaagt ggaacgggtg ctgaacatgg
    21181 tggacggcgt tctgctgctg gtagacgctt atgaaggccc catgccccag accaaatacg
    21241 tgctgcggaa agcactggaa catcacctga aaccggtggt ggtcatcaac aagatcgacc
    21301 gtccggatca gcgggtggaa gaagtggtgg atgaagtcct ggatctgttc atcgaactga
    21361 acgccaacga cgaccagctg gacttcccgg tggtttatgc ctccgccaag aagggtgttg
    21421 ccaagctgtc catggacgac gaaagcgaca acctggaacc cctgttccgc accattatcg
    21481 acagcattcc cgctcctgat gtggacgtgg acgctcccct gcagatgctg gtgaacaccc
    21541 tggaccacga tgactatgtg ggccggatcg tggtgggccg tgtggtccgc ggcaccatca
    21601 aaaacggaca gaacgtgtgc ctgatgcacg a
//
