LOCUS       c00001_NZ_MUXT..       10921 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_MUXT01000001.1 Moraxella canis strain CCUG 8415A
            8415T_ctg_0000001, whole genome shotgun sequence.
ACCESSION   NZ_MUXT01000001
VERSION     NZ_MUXT01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:10:24
            Original ID  :: NZ_MUXT01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 405441
            Orig. end    :: 416362
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10921
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[410441:411362](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5921)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10921
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10921
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(180..1289)
                     /locus_tag="ctg1_370"
                     /transl_table=11
                     /translation="MKTTLKQLRQTQANPAVSIFVKTHRTHPENEQDAIALKNQLKIAE
                     DRITEEYDKRTADAILANITAQTDELDHNYNLDMLAIFATDSSAEVLRLPFDAKERVII
                     GNKFATRDLMRDLSEAVNYYVLVVTSENARLLVGVNNVLVKEVIGSSPRQENQDELSFP
                     IKNTTLPTGSKSDRTGSSDDHSYLKEFMNRVDKSLQRIHNASPLPVILVGDSRTLGFYE
                     QVCDNPSIILGKVDNLPHLKDGSAQEIIDGVQELVEDKRKTRYENAQGELEKARNEKMV
                     RTDLQQIYRSAVEGNAVMLLVRQGHSVPATIDEQNATLLVAENASDEGVNDDAVAEIIE
                     LVDHNGGEVVFVPRDQMSEKEPIALITRY"
     PFAM_domain     complement(402..926)
                     /aSDomain="baeRF_family3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18845.3"
                     /description="Bacterial archaeo-eukaryotic release factor
                     family 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_370_0033"
                     /evalue="1.20E-32"
                     /label="ctg1_370"
                     /locus_tag="ctg1_370"
                     /protein_end="296"
                     /protein_start="121"
                     /score="113.7"
                     /tool="antismash"
                     /translation="NYYVLVVTSENARLLVGVNNVLVKEVIGSSPRQENQDELSFPIKN
                     TTLPTGSKSDRTGSSDDHSYLKEFMNRVDKSLQRIHNASPLPVILVGDSRTLGFYEQVC
                     DNPSIILGKVDNLPHLKDGSAQEIIDGVQELVEDKRKTRYENAQGELEKARNEKMVRTD
                     LQQIYRSAVEGN"
     CDS             complement(1668..2633)
                     /locus_tag="ctg1_371"
                     /transl_table=11
                     /translation="MKKTAILLVNLGTPDAPTPDAVRRYLREFLSDTRVIEIPKVIWQV
                     ILNCFVLTTRPKRVAHAYQSVWMDGGSPLLVILKNQAKDLQDLLAQQGIDIPVHPATTY
                     GNPSVKSVMTDLMSQGVESFIILPLFPQYSATSTAAAFDKIAKLLLNTRNVPDLNFIKD
                     YHDHPDYIEALAQSVERYWAEHGRADKLLMSFHGIPKPYADKGDPYPEQCRTTAVLLAD
                     RLGLPMDAWAISFQSRFGAQEWLKPYTDELLAEWGASGLSVQVMSPAFSADCLETLEEL
                     AVENRDNFLEAGGRAYDYIPALNTDPLHIQMMANVIKKYL"
     aSDomain        complement(1671..2633)
                     /aSDomain="TIGR00109"
                     /aSTool="tigrfam"
                     /description="hemH: ferrochelatase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_371_0008"
                     /evalue="8.20E-97"
                     /identifier="TIGR00109"
                     /label="ctg1_371"
                     /locus_tag="ctg1_371"
                     /protein_end="321"
                     /protein_start="0"
                     /score="322.4"
                     /tool="antismash"
                     /translation="MKKTAILLVNLGTPDAPTPDAVRRYLREFLSDTRVIEIPKVIWQV
                     ILNCFVLTTRPKRVAHAYQSVWMDGGSPLLVILKNQAKDLQDLLAQQGIDIPVHPATTY
                     GNPSVKSVMTDLMSQGVESFIILPLFPQYSATSTAAAFDKIAKLLLNTRNVPDLNFIKD
                     YHDHPDYIEALAQSVERYWAEHGRADKLLMSFHGIPKPYADKGDPYPEQCRTTAVLLAD
                     RLGLPMDAWAISFQSRFGAQEWLKPYTDELLAEWGASGLSVQVMSPAFSADCLETLEEL
                     AVENRDNFLEAGGRAYDYIPALNTDPLHIQMMANVIKKYL"
     PFAM_domain     complement(1677..2627)
                     /aSDomain="Ferrochelatase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00762.21"
                     /description="Ferrochelatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_371_0034"
                     /evalue="3.90E-107"
                     /label="ctg1_371"
                     /locus_tag="ctg1_371"
                     /protein_end="319"
                     /protein_start="2"
                     /score="358.1"
                     /tool="antismash"
                     /translation="KTAILLVNLGTPDAPTPDAVRRYLREFLSDTRVIEIPKVIWQVIL
                     NCFVLTTRPKRVAHAYQSVWMDGGSPLLVILKNQAKDLQDLLAQQGIDIPVHPATTYGN
                     PSVKSVMTDLMSQGVESFIILPLFPQYSATSTAAAFDKIAKLLLNTRNVPDLNFIKDYH
                     DHPDYIEALAQSVERYWAEHGRADKLLMSFHGIPKPYADKGDPYPEQCRTTAVLLADRL
                     GLPMDAWAISFQSRFGAQEWLKPYTDELLAEWGASGLSVQVMSPAFSADCLETLEELAV
                     ENRDNFLEAGGRAYDYIPALNTDPLHIQMMANVIKK"
     CDS             complement(3011..3604)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 105.6;
                     E-value: 3.8e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_372"
                     /transl_table=11
                     /translation="MADINTIIDDDVIAELYIPMYRFAYNQLGDEQCARDVVQEALMNA
                     LKYADSFQGRSALKSWLFAILKNKISDHIRQTQKYIPLSDFSNDEQDDASFLEYLFDAN
                     GHWYADSQIQALSQTLENPADCVEQDDFWAVLELCLDNLPKEQARAFLMKEYIELDTEV
                     ICQELNISRQNYYVLMHRARLRLQTCLSIKWLDC"
     aSDomain        complement(3017..3583)
                     /aSDomain="TIGR02943"
                     /aSTool="tigrfam"
                     /description="Sig70_famx1: RNA polymerase sigma-70 factor,
                     TIGR02943 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_372_0009"
                     /evalue="1.20E-59"
                     /identifier="TIGR02943"
                     /label="ctg1_372"
                     /locus_tag="ctg1_372"
                     /protein_end="196"
                     /protein_start="7"
                     /score="199.3"
                     /tool="antismash"
                     /translation="IDDDVIAELYIPMYRFAYNQLGDEQCARDVVQEALMNALKYADSF
                     QGRSALKSWLFAILKNKISDHIRQTQKYIPLSDFSNDEQDDASFLEYLFDANGHWYADS
                     QIQALSQTLENPADCVEQDDFWAVLELCLDNLPKEQARAFLMKEYIELDTEVICQELNI
                     SRQNYYVLMHRARLRLQTCLSIKWLD"
     aSDomain        complement(3035..3571)
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_372_0010"
                     /evalue="1.00E-24"
                     /identifier="TIGR02937"
                     /label="ctg1_372"
                     /locus_tag="ctg1_372"
                     /protein_end="190"
                     /protein_start="11"
                     /score="85.0"
                     /tool="antismash"
                     /translation="VIAELYIPMYRFAYNQLGDEQCARDVVQEALMNALKYADSFQGRS
                     ALKSWLFAILKNKISDHIRQTQKYIPLSDFSNDEQDDASFLEYLFDANGHWYADSQIQA
                     LSQTLENPADCVEQDDFWAVLELCLDNLPKEQARAFLMKEYIELDTEVICQELNISRQN
                     YYVLMHRARLRLQTCL"
     PFAM_domain     complement(3047..3199)
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_372_0036"
                     /evalue="7.90E-09"
                     /label="ctg1_372"
                     /locus_tag="ctg1_372"
                     /protein_end="186"
                     /protein_start="135"
                     /score="35.2"
                     /tool="antismash"
                     /translation="LELCLDNLPKEQARAFLMKEYIELDTEVICQELNISRQNYYVLMH
                     RARLRL"
     PFAM_domain     complement(3368..3559)
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_372_0035"
                     /evalue="4.50E-13"
                     /label="ctg1_372"
                     /locus_tag="ctg1_372"
                     /protein_end="79"
                     /protein_start="15"
                     /score="48.9"
                     /tool="antismash"
                     /translation="LYIPMYRFAYNQLGDEQCARDVVQEALMNALKYADSFQGRSALKS
                     WLFAILKNKISDHIRQTQK"
     CDS             complement(3608..4252)
                     /locus_tag="ctg1_373"
                     /transl_table=11
                     /translation="MNKIMNLYLAVAQLLPKLDFFVLLALRLYLAPIFIVAGWQKLTQF
                     DSMVSWFGDVSWGLGLPFAPLWVILVIFAELIGGAALLFGVLTRWFALMLSMTMMVAIV
                     KVHLKNGWYAITPTDPTTNISQLFSYLPEGQSSLQNSLAAGERLAKANEILQSQGDFEW
                     LTQTGNFVILNNGVEFGVTYLIMLLVLLVFGAGRYLSVDDWFYRLIFIKKR"
     PFAM_domain     complement(3932..4186)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_373_0037"
                     /evalue="3.60E-20"
                     /label="ctg1_373"
                     /locus_tag="ctg1_373"
                     /protein_end="107"
                     /protein_start="22"
                     /score="72.4"
                     /tool="antismash"
                     /translation="LLALRLYLAPIFIVAGWQKLTQFDSMVSWFGDVSWGLGLPFAPLW
                     VILVIFAELIGGAALLFGVLTRWFALMLSMTMMVAIVKVH"
     CDS             complement(4249..4995)
                     /locus_tag="ctg1_374"
                     /transl_table=11
                     /translation="MKAPNLKHFQQDFGDYIRKQAHESCDTIPKRVGELYQTLIFRAVA
                     GFVNQCFPVCRKIIDEPVWHRLLLSFIKQGDMSSPYFSEINKQFVDYLDEDIITAFDLH
                     PCVAELAHYEWIELYVDNLPNIPPKLFLEEDNRQIFINSTLQVLKYSWEVHQIGSEYLP
                     TKPQDTFVLVYRSLDEGYQTAFMQINIVSFIVLTFIQETDKVYPSPADLIVDIVNYFGL
                     KADLMDQTEELFRTLFDAQVMIEIKR"
     PFAM_domain     complement(4717..4971)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_374_0038"
                     /evalue="6.00E-14"
                     /label="ctg1_374"
                     /locus_tag="ctg1_374"
                     /protein_end="93"
                     /protein_start="8"
                     /score="52.1"
                     /tool="antismash"
                     /translation="FQQDFGDYIRKQAHESCDTIPKRVGELYQTLIFRAVAGFVNQCFP
                     VCRKIIDEPVWHRLLLSFIKQGDMSSPYFSEINKQFVDYL"
     CDS             complement(5001..5921)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_375"
                     /sec_met_domain="DUF692 (E-value: 1.6e-98, bitscore: 323.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIKQVKSQSVVPMGAGMGFRREMMAQMDGRYSLSHEIDFFEVS
                     PENWMNSQGVMGGRFDALLRSYSERFDFVCHGLSLSIGGTRQLDVQHVKNIKQFMQRHE
                     IELFTEHLAWCGDSKGYLYDLLPMPCTSEAVTWVADRISQVQDILGRQIGLENASYYYR
                     PKESEMSDCEFITAVIEEADCLLHLDVNNIFVNSQNFGFDAQEYLHQLPLERVCYLHVA
                     GHYADHDGLIIDTHGESVVNQVWALLESTYDEIYQRTAKTADMIPTCLERDFNFPSLEQ
                     LIDEVNHIRWLQSAQVENLSKTKTI"
     PFAM_domain     complement(5046..5876)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_375_0039"
                     /evalue="4.20E-93"
                     /label="ctg1_375"
                     /locus_tag="ctg1_375"
                     /protein_end="292"
                     /protein_start="15"
                     /score="311.5"
                     /tool="antismash"
                     /translation="GAGMGFRREMMAQMDGRYSLSHEIDFFEVSPENWMNSQGVMGGRF
                     DALLRSYSERFDFVCHGLSLSIGGTRQLDVQHVKNIKQFMQRHEIELFTEHLAWCGDSK
                     GYLYDLLPMPCTSEAVTWVADRISQVQDILGRQIGLENASYYYRPKESEMSDCEFITAV
                     IEEADCLLHLDVNNIFVNSQNFGFDAQEYLHQLPLERVCYLHVAGHYADHDGLIIDTHG
                     ESVVNQVWALLESTYDEIYQRTAKTADMIPTCLERDFNFPSLEQLIDEVNHIRWL"
     CDS             complement(6003..6326)
                     /locus_tag="ctg1_376"
                     /transl_table=11
                     /translation="MSNSKQITGLAVATLLATGLVACKSEAMPKPQAKSMEQGYQNSTK
                     PMGGMMTKDAEGKCGEGKCAATPTPASKNANANCGASAEKMGSANCGASANKNANANCG
                     ASK"
     CDS             6516..8057
                     /locus_tag="ctg1_377"
                     /transl_table=11
                     /translation="MKYLSKNVSTKTQQSLIALMIGAAVLTACSEPNRTAQQNSSEPSQ
                     AINTDSAKGYHVHEVALGDMVVGEMTAPQRGLIVLPSTKADTKYPLVIISHLRAPNCSG
                     GEFAYPCPEGQTELRFDQGMQYLAEHLADSGYAVIVPDYSVVFSGDMVTEPYDQAALWR
                     ETIQAFMTHIQQSPQMSSLVDFERVGLFAHSRSGNMLDAAHALFGEKLKGVLTYGPSPD
                     TYDIAEISAAPVDVPYLSILGDLDKDVDQAVNQWIGHWISTPRQTPATVATVPGFGHNY
                     INRALSSAKIDERIGCDVLDCPDANAHEQLVMQTAAQWFDATLKGAKTTLPIKAADALP
                     TTLADHEVSWLAATPKAISTVNFDDFKPFQGSEVTLCRYEDPMNPFQPKDACPRPELGV
                     ITTMTYIAQFSQAAADTAVKGAQGLAVHLSPWGSQTKPTNVTITLHADDGQQLALPIAA
                     DHPAIKSRLTEFDNGVYQLSTVRLPLPAEWQNHTITHLTITTDGNKIEVRSVDFY"
     CDS             complement(8263..8460)
                     /locus_tag="ctg1_378"
                     /transl_table=11
                     /translation="MSNITPEYTRRAIKKYEERLVKKIVTFSVDADADILTAIDADDTP
                     FTALALSLLYKHYGIEQPKG"
     CDS             complement(8712..8885)
                     /locus_tag="ctg1_379"
                     /transl_table=11
                     /translation="MSQPKKPARKQKSVVFHKEKDQALIQAVQNDQSVAFSALMRQLLR
                     EHYQLSDSQKYS"
     CDS             complement(8938..9051)
                     /locus_tag="ctg1_380"
                     /transl_table=11
                     /translation="MQTTVDGLILLGGVAVPLLLVRHVAWIQNIWIKNGKR"
     CDS             9197..10261
                     /locus_tag="ctg1_381"
                     /transl_table=11
                     /translation="MTVQTFTPDTRPAPKKAVQGEKLRGYDKVARIPIKVIPSVDTLKK
                     PDWIRVKLSSPAEVERIKSTLRKQKLYTVCEEAACPNLPQCFGDGTATFMIMGDICTRR
                     CPFCEVAHGRPNPLDKDEPRHTAETILGLGLKYAVITSVDRDDLKDGGAGHFVEVINES
                     KALSPNCLIEILVPDFRGREQVALDLLTETAPDVFNHNIETVLRLYKAFRPGSDYQHSL
                     NLLKDYKARRPDVATKCGFMVGLGETEEEVYALLDDLKAHDVDIVTIGQYLAPSKNHAP
                     VDRYVHPDEFARYTEYGKKLGFFNIWANPMVRSSYFADRQYYGEDCPPPARSAKALAEE
                     KLAKAQNGEKTGCF"
     PFAM_domain     9317..9436
                     /aSDomain="LIAS_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16881.7"
                     /description="N-terminal domain of lipoyl synthase of
                     Radical_SAM family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_381_0040"
                     /evalue="1.80E-06"
                     /label="ctg1_381"
                     /locus_tag="ctg1_381"
                     /protein_end="80"
                     /protein_start="40"
                     /score="28.4"
                     /tool="antismash"
                     /translation="DTLKKPDWIRVKLSSPAEVERIKSTLRKQKLYTVCEEAAC"
     aSDomain        9317..10156
                     /aSDomain="TIGR00510"
                     /aSTool="tigrfam"
                     /description="lipA: lipoyl synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_381_0011"
                     /evalue="4.50E-116"
                     /identifier="TIGR00510"
                     /label="ctg1_381"
                     /locus_tag="ctg1_381"
                     /protein_end="320"
                     /protein_start="40"
                     /score="385.3"
                     /tool="antismash"
                     /translation="DTLKKPDWIRVKLSSPAEVERIKSTLRKQKLYTVCEEAACPNLPQ
                     CFGDGTATFMIMGDICTRRCPFCEVAHGRPNPLDKDEPRHTAETILGLGLKYAVITSVD
                     RDDLKDGGAGHFVEVINESKALSPNCLIEILVPDFRGREQVALDLLTETAPDVFNHNIE
                     TVLRLYKAFRPGSDYQHSLNLLKDYKARRPDVATKCGFMVGLGETEEEVYALLDDLKAH
                     DVDIVTIGQYLAPSKNHAPVDRYVHPDEFARYTEYGKKLGFFNIWANPMVRSSYFADR"
     PFAM_domain     9488..9973
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_381_0041"
                     /evalue="1.30E-09"
                     /label="ctg1_381"
                     /locus_tag="ctg1_381"
                     /protein_end="259"
                     /protein_start="97"
                     /score="38.7"
                     /tool="antismash"
                     /translation="GDICTRRCPFCEVAHGRPNPLDKDEPRHTAETILGLGLKYAVITS
                     VDRDDLKDGGAGHFVEVINESKALSPNCLIEILVPDFRGREQVALDLLTETAPDVFNHN
                     IETVLRLYKAFRPGSDYQHSLNLLKDYKARRPDVATKCGFMVGLGETEEEVYALLDDL"
ORIGIN
        1 gcaatgcgtc caagccaaac gctcaatcaa gcacttgagc tacttaaata aagacaagcc
       61 taaaaaaata tcccaaacct ttgggatatt ttttatttag tcttcctaaa ataaaaaacc
      121 acgcctatct tgataggcgt ggttttttag tcattgatct aatcaatgaa tccaatcaat
      181 tagtagcgag taatcaatgc gattggctct ttttcgctca tctgatcacg cggtacaaac
      241 acaacttcac caccattatg atcaaccaat tcaatgattt ctgccaccgc atcatcattc
      301 acgccttcat ctgaagcatt ctcagcgacc aacaaagttg cattttgttc atcaatcgtc
      361 gcaggcacgc tatgaccttg gcgaaccaat agcatcacgg cattgccttc aactgcagag
      421 cgatagattt gctgaagatc cgtgcgtacc attttttcgt ttcgcgcttt ttcaagttcg
      481 ccttgagcat tttcgtaacg agttttgcgc ttatcttcaa ccaattcttg aacaccgtca
      541 atgatttctt gggcgctgcc atctttgaga tgtggcaagt tatcaacctt acccaaaatg
      601 attgatggat tatcacacac ttgctcataa aaacccaatg tacgcgaatc accgaccaaa
      661 atcacaggca gtggcgatgc gttatgaata cgctgcaagc tcttatcgac gcgattcata
      721 aactctttta aatagctgtg atcgtctgac gatcctgtgc gatccgattt actgcctgtt
      781 ggtagcgtag tgtttttgat tgggaaagac agctcatctt gattttcttg gcgcggactg
      841 ctgccaatga cttctttaac caacacatta ttgacaccga caagcaagcg ggcgttttcg
      901 ctagtcacaa ccagcacata gtaatttacc gcttctgaca gatcacgcat cagatcgcgc
      961 gtcgcaaatt tattaccgat gatcacgcgc tctttggcgt caaaaggcag gcgaagcact
     1021 tcggcgctag aatctgtcgc aaaaatcgcc aacatatcca aattatagtt atgatcaagc
     1081 tcatcagttt gggcagtgat gttagctaag atggcatcag ccgtgcgttt gtcatattct
     1141 tccgtgatac gatcttcagc aatttttaac tgatttttta aagcgatggc atcttgctca
     1201 ttttcaggat gcgtgcgatg ggtcttaaca aagatactga ccgcaggatt ggcttgggtt
     1261 tgtcttaatt gctttagtgt cgttttcatg tatttctcct ataaattttt ccgttcatca
     1321 ctcatcgctt tatttgctga ttaattctaa aaacttagtt ataaatttca taaattgata
     1381 taagttcatg aattaacaga tcaaattgtg atgtgatgat ttgagtataa caactctctc
     1441 ccagcctgcg taggcgattt tgtgcgcttt ttgcccttga tgcgttattt tatgttagtt
     1501 tcttaccccc atgaaacact gtgtacctta ggggtgatca aggtaagata ttagttaaat
     1561 tttttaaatg atcaaaccac ttaaccatgg ctaaatttta ctcgtaaaaa tccccaaaac
     1621 caacaggctt tggggaacta gcaagttttc gtaattcatc tttgaactta taaatatttt
     1681 ttaatcacat ttgccatcat ctgaatgtgc agcggatccg tatttaatgc aggaatatag
     1741 tcataagctc gcccccctgc ctctaagaaa ttatccctat tttcaacggc aagctcttcg
     1801 agcgtctcaa ggcagtcagc agaaaatgct ggactcataa cctgcacaga aagccctgac
     1861 gcaccccact cagcaagcag ctcgtcagtg tatggcttta gccattcttg ggcaccaaaa
     1921 cgcgactgga aactgatcgc ccatgcatcc atcggcaaac ctaagcgatc tgctaacaaa
     1981 actgccgtgg ttcgacattg ttcaggatat ggatcgcctt tatctgcata gggcttgggg
     2041 ataccatgaa aactcatcaa aagcttatca gcgcgcccat gctccgccca gtagcgctca
     2101 acagactgcg ccaatgcttc gatataatca ggatgatcgt ggtaatcctt gataaagttt
     2161 aggtcaggta catttctggt gtttaatagt agcttggcaa ttttatcaaa ggcggcagcc
     2221 gttgaagtgg ctgaatactg cggaaaaagc ggcaaaataa tgaaagactc cacgccctgc
     2281 gacatcaaat ccgtcatcac cgatttgaca gaaggattgc cataagtggt tgcaggatgg
     2341 acaggtatat caatgccctg ctgggcaaga agatcctgta ggtctttagc ttgatttttg
     2401 agtatcacca ataacggtga gccgccgtcc atccacacac tttgataggc gtgggcgaca
     2461 cgcttaggtc tggtcgtcag cacaaagcaa tttaaaatca cctgccaaat cactttgggg
     2521 atttcgatca cgcgcgtatc gctcaaaaat tcacgcaaat aacgacgcac cgcgtcaggc
     2581 gttggggcat ctggcgtacc caaattaacc aggagtatgg ctgttttttt cataaggcaa
     2641 aacaaattaa gcaaagtttg attttatcat ttttttaata aaaaatctca gccaaactta
     2701 ggatttatca ttaactttat caatcatagc ttttggatgt tttggttggt gcgcttgtct
     2761 gatcgagtga tgctgtcttt gtgattgagg ttttaccagc tctatgatga cgcacaagct
     2821 gcctaatcag ttggttgttt tgctcaaatg tccgacactt tttacaaatc atcaaatgtg
     2881 tcttaaccgc caatttttct gaggcgctca atgattcttc atatgagcgg ctaatcagct
     2941 ctgttgtttt ttggcaattt gccataaatt ttatcataaa tttaagcact ttattaaaat
     3001 cttggagcaa ctaacagtct agccatttga tcgacaaaca ggtctgtagt ctcaatctgg
     3061 cacgatgcat gagcacataa taattctgac gactgatgtt taattcttgg cagataacct
     3121 ctgtgtcaag ctcaatatac tctttcatca aaaacgcgcg agcctgctct ttgggtaaat
     3181 tatccaaaca caactcaagc accgcccaaa aatcatcttg ctcgacacaa tcagcagggt
     3241 tttccaaggt ttggcttagt gcttgaattt ggctatcagc gtaccaatgc ccattggcat
     3301 caaacaaata ttcaagaaat gaagcatcat cttgctcatc atttgaaaag tcggataaag
     3361 gtatgtattt ttgggtttgg cgaatatgat cactgatctt attttttaag atggcaaaca
     3421 gccaactttt taatgccgat ctgccctgaa agctgtcggc gtattttaaa gcattcatca
     3481 aagcttcttg taccacatct cgtgcgcact gctcatcgcc caattgatta taggcaaacc
     3541 gatacatggg tatataaagc tcagcaatga catcgtcatc aattatcgta ttgatatcag
     3601 ccatgattta tcttttctta ataaaaatca gacgataaaa ccaatcatcc acgctcaaat
     3661 aacgccctgc gccaaacacc aataacacca gtagcatgat caaataagta acaccaaatt
     3721 ctacgccatt attaagtatg acaaaattcc ctgtttgagt cagccactca aaatcaccct
     3781 gagattgtaa aatttcattg gcttttgcca gtcgctcgcc agcagcaagc gaattttgta
     3841 aacttgattg accttcaggc aggtaagaaa acagctgaga gatgttcgtt gtagggtctg
     3901 tgggcgtaat ggcgtaccat ccgtttttca aatgcacctt aacaattgca accatcatgg
     3961 tcattgacaa catcaaggca aaccaccgag ttaacacacc aaataataat gctgcaccgc
     4021 cgatcaattc tgcaaaaatc accaaaataa cccaaagggg cgcaaatggc aatccaagcc
     4081 cccatgacac atccccaaac catgagacca tactatcaaa ctgcgtcaat ttttgccaac
     4141 ctgccacaat aaaaataggt gctagatata aacgcagcgc caataaaaca aaaaaatcaa
     4201 gcttcggcag cagctgagcg acagccagat ataaattcat tatcttattc atcgtttaat
     4261 ctcaatcatg acttgagcgt caaataaagt tcggaataat tcctcagtct gatccatcaa
     4321 atcagcctta agcccaaaat aattcacaat atcgacaatc aaatcagctg ggcttggata
     4381 caccttatca gtctcttgga taaaagttaa tacaataaag ctgacgatat ttatctgcat
     4441 aaaagccgtc tgataaccct catctaagga gcgatatacc aacacaaagg tatcttgtgg
     4501 ctttgtcggc aaatactcac taccaatttg atgaacctcc caagaatact ttaagacttg
     4561 taaggtgctg ttgataaaaa tctgccgatt atcctcttcc aaaaaaagct tcggcgggat
     4621 gttgggcaaa ttatcaacat atagctctat ccattcatag tgagcaagct ctgcaacgca
     4681 cggatgaaga tcaaacgcag tgataatatc ctcatccaaa taatccacaa actgcttatt
     4741 aatttcacta aaatacgggc tggacatatc gccttgcttt ataaaagaca ataaaagcct
     4801 atgccaaact ggctcatcaa tgatcttgcg acaaacagga aagcattgat tgacaaaacc
     4861 tgccactgca cgaaaaatca aagtttggta aagctctccg acgcgctttg ggatagtgtc
     4921 acagctttca tgggcttgct tgcgaatata gtcgccaaaa tcttgttgga aatgttttaa
     4981 atttggtgct ttcataccga tcaaatggtc ttagttttag ataaattttc cacttgggca
     5041 gattgtagcc agcggatatg attcacttcg tctatcagtt gctcgaggct tggaaagtta
     5101 aaatctcgct ccagacaagt tggaatcata tcagcagttt ttgcggtacg ctgataaatc
     5161 tcatcataag tagattcaag caatgcccat acttgattaa caacactttc accatgcgtg
     5221 tcaataatca atccatcatg atcagcataa tgaccagcga catgcaaata acagactctc
     5281 tccaaaggca gctggtgtag atattcctgc gcatcaaaac caaaattttg gctattaaca
     5341 aaaatattat taacatctaa gtgtagcaaa cagtcagctt cttcaatcac cgctgtgata
     5401 aattcacaat cggacatttc actttctttt gggcgataat aataagatgc gttttctaag
     5461 ccaatttgcc gaccaagaat atcttgcact tgactaatcc tgtcagctac ccatgtaacc
     5521 gcctcagatg tgcaaggcat aggtagtaag tcatacaaat atcccttgga atcgccacac
     5581 cacgccaaat gctcagtaaa taactcaatc tcatgacgct gcataaactg cttaatattt
     5641 ttgacatgct gaacatccag ctgtcttgta ccgcctatgg ataacgacaa cccatggcag
     5701 acaaaatcaa aacgctcact ataagagcga agcaaggcat caaatctccc gcccatgaca
     5761 ccttgtgaat tcatccaatt ttcaggtgaa acctcaaaaa aatcaatctc atgggataat
     5821 gagtagcgcc catccatctg cgccatcatc tcacgtcgaa accccatgcc agcgcccatc
     5881 ggcacgactg actgactttt gacctgcttg atcgttgaca tgatttacac ccatcaatct
     5941 tatgtcatac cactttacga tgataaagca ttgcgtcttt atcatcgtaa atctcggttt
     6001 atttacttag aagcaccaca attggcgttg gcatttttat ttgcgctggc accacagttg
     6061 gcactaccca ttttctcagc gcttgcgcca caattggcat tggcgttttt gcttgctggg
     6121 gtgggagtgg cggcgcattt accttcgccg catttacctt cggcatcttt ggtcatcatg
     6181 ccgcccatcg gttttgtgct attttgatag ccttgctcca ttgattttgc ttgcggcttg
     6241 ggcatggctt ctgatttgca agccaccaat ccagttgcaa gtaatgtcgc aacagccagc
     6301 ccagtaattt gctttgaatt tgacataaca ttctcctttt gaataaaaac tcaatcatca
     6361 tcacagcatc acaaaaccat ttgtgacacc tattagacac atctcaatcc caaattctta
     6421 cacaaatttt taaaaaattg cgttatcatt ttcatcccct atgaatgctc atctaagcta
     6481 taataagtgc ttaaaatcat tgatgtggtc atcttatgaa atatttatca aaaaacgtat
     6541 caaccaaaac ccagcaatca ctcatcgcct taatgatcgg ggcggcggta ttaacggctt
     6601 gttctgagcc taatcgcacg gcgcagcaaa acagctccga gcccagtcaa gccattaaca
     6661 cggatagcgc caaaggctat catgtccatg aagtggcttt gggtgacatg gttgttggtg
     6721 agatgaccgc tccacagcgc ggcttgattg tcctgcccag cacaaaagcc gataccaaat
     6781 atcccttggt gatcatcagt catctgcgtg cgccgaattg cagtggtggt gagtttgctt
     6841 atccttgccc cgaaggtcag actgagctgc gctttgacca aggcatgcag tatctggcag
     6901 agcatctggc agactcaggc tatgcggtga ttgtgcctga ttatagcgtt gtgtttagtg
     6961 gagatatggt gacagagcct tatgaccaag ccgcattatg gcgtgaaact atccaagcat
     7021 tcatgactca catacagcag tcgccacaaa tgagtagctt ggtggatttt gagcgtgtgg
     7081 gcttgtttgc gcattctcgc tcaggcaata tgctagatgc tgcccatgcg ctttttggcg
     7141 aaaaactcaa aggcgtgctg acctatggtc catcgccaga tacctatgat atcgccgaga
     7201 tctctgctgc gcctgtggat gtgccttatc tgtcgatctt aggtgatctt gacaaagatg
     7261 tcgatcaagc cgtcaatcag tggattgggc actggatcag cacaccacgc cagacgccag
     7321 ccaccgttgc cacggtgcca gggtttggtc ataactatat caaccgtgcg ctcagctcag
     7381 caaagattga tgagcgcatc ggctgtgatg tgctagattg tcctgatgcc aatgcccacg
     7441 aacagctggt gatgcaaacc gccgctcagt ggtttgatgc caccttaaaa ggcgccaaga
     7501 ccactttacc catcaaggca gcagacgcac ttcccaccac attagccgat catgaagtca
     7561 gctggcttgc cgccacacca aaagcgatca gcaccgtcaa ttttgatgac ttcaaacctt
     7621 ttcaaggcag cgaagtgacg ctctgtcgct acgaagatcc gatgaatcca tttcagccaa
     7681 aagatgcctg cccacgacca gagcttggtg tgataaccac gatgacttat atcgcacaat
     7741 ttagccaagc tgctgcggac acggcggtca aaggtgcaca aggtttggcg gttcatctgt
     7801 cgccatgggg cagccagacc aagcccacca atgtgacgat aaccctacat gctgacgacg
     7861 gtcagcagct ggcactgccc atcgctgcag atcatcctgc catcaaaagc cgcttaaccg
     7921 aatttgacaa tggcgtctat cagctatcca ccgtacgcct gcccctaccg gctgagtggc
     7981 aaaatcacac aatcacccat ctcaccatca cgaccgacgg gaacaagatc gaagttcgca
     8041 gtgtggattt ttattgatac taaaaatagc ctggcattga gtcaggcttt tataggataa
     8101 atgtgacaaa cggtgattgg catgtcgatg cgattatcct aatccgcgga atgtggatga
     8161 tttagaaaat ttatttatca agcatacctt ttctgtggtc agggcgtcgg tgagcgttta
     8221 gagcgcgttt atcggtttac tggtttaaat gctaaaaaat catcatccct taggctgctc
     8281 gatgccataa tgcttgtata gtagcgacaa agctagcgcc gtgaatggtg tatcatccgc
     8341 atcaatggcg gtcagaatat cagcatctgc atcaacagag aaggtgacaa tttttttaac
     8401 caacctttct tcatattttt tgatggctcg tctggtgtat tctggggtaa tattgctcat
     8461 ggtttatttt tcctaatttg acaattaact tccattattc ttaagataag aggattcttc
     8521 ctaacagacg gtcaccgacc gcaagaatat ttttactgcc attaatacct ctatcatgcg
     8581 gtatgccatg ctttgtacag atccattctc ttattgccaa acctgctctc cctttcggat
     8641 taccatacct atcgccacag cacgaacaag tttgggcagt gtatttctca atagattttt
     8701 agcaagtcaa attatgaata tttttgacta tctgaaagtt gataatgctc tctgagcagt
     8761 tggcgcatca atgcactaaa agcaacagat tgatcatttt gcactgcttg aattaatgct
     8821 tgatctttct ctttatgaaa aaccacactt ttttgtttgc gcgctggttt ctttggttgg
     8881 ctcatgataa tatcctcatt caaaattcaa tacattatat aataaagaat atgctatcta
     8941 ccgtttaccg ttcttaatcc aaatattttg aatccatgcc acatgccgca caagcagcaa
     9001 aggcaccgcc acccctccca acagaattaa gccatctacg gtcgtttgca ttggcaccct
     9061 ctaaatctat cccatacaat ccaatattag cataagattt ttcacaataa aagaattctt
     9121 gcattttgtt atttatgcca atttggcgta taataagatg atttttgcag aatttttatg
     9181 atatttagga taagccatga ctgtccaaac ctttaccccc gatactcgtc ctgcacccaa
     9241 aaaagcggtg caaggcgaga aactgcgcgg ctatgataaa gtcgctcgca ttcccatcaa
     9301 agttatccca agcgtcgaca ctctcaaaaa acccgactgg attcgcgtga agctctcaag
     9361 tcctgccgaa gttgagcgca tcaaatccac gctacgcaaa caaaagctct acaccgtttg
     9421 cgaagaagcc gcctgcccaa acctgccaca gtgctttggt gatggtacag cgacttttat
     9481 gattatgggt gatatctgta ctcgtcgctg cccgttttgt gaagtggcgc acggtcgccc
     9541 aaatcctttg gataaagacg agccgcgcca tactgccgag accattttag gcttggggct
     9601 aaaatatgcc gtcatcactt cggtggacag agatgacctc aaagacggcg gtgcaggtca
     9661 ctttgtggaa gtgatcaatg aatccaaagc actaagcccc aattgcttga ttgagatttt
     9721 ggtgcctgac ttccgcgggc gcgagcaggt tgcgcttgat ttattgaccg aaactgcgcc
     9781 agatgtattt aatcataata tcgaaaccgt gctgcgtctt tataaagcgt ttcgacctgg
     9841 ctctgactat cagcactcac tgaatctact caaagactac aaagcccgcc gtcctgatgt
     9901 cgcgaccaaa tgcggcttta tggtgggtct tggcgaaacc gaagaagaag tgtacgcact
     9961 gcttgacgac ctaaaagcac atgatgttga catcgtcacc atcggtcaat atcttgcccc
    10021 aagtaaaaac catgcccccg tggacagata tgtgcatcct gatgagtttg cgcgctacac
    10081 cgaatacggt aagaaattgg gcttttttaa catctgggca aacccaatgg tgcgctcaag
    10141 ctactttgcc gatcgtcaat attatggcga agactgcccg ccgccagctc gcagcgccaa
    10201 agcacttgcc gaagaaaaac tggccaaagc tcaaaacggt gagaaaactg gctgtttttg
    10261 atcgcgctga gattatccct gttaaagtgg cgtataacat aaagctttac gccacatatt
    10321 ttaagacata tggcttgttg gcggctgatc agtgatgcgc tcacttggca gtttgacctt
    10381 ggccatgttt aattttttat ccaaaaccac taccatgact caaaccatcc tttcatccaa
    10441 cggcatccac cgcctacacc atactttttt tgtaccaaaa ggtgagatca aatccaccct
    10501 gcttatcgta catggcatga ctgagcatgg cggccgatat gcgagatttg cccaattttt
    10561 ggcagatcat ggcgtactgg tggcgacata tgatcagctt gggcatggtc agacggtcaa
    10621 agataagtat gagcttgggt attttgatga caagcatcct gtgcaagcgc tgtcaaaaga
    10681 tgtcatcatc atggcagata agctcaaaga gcacgcgcca tcagtgccgc attttatcat
    10741 gggtcattcg atgggctcgt ttatcgtgcg ttcggtgctc attcatcaca gcacgcgatt
    10801 tgatggcgtg ctattgatgg gtacagcgga taattttggt cttttaagcc gtaccactta
    10861 tgcagcgctt agcctactca acaaactctc ccccaagcag gtcaatcaac acgccgctga
    10921 g
//
