LOCUS       NZ_CP020399.1          10816 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP020399.1 Burkholderia multivorans strain FDAARGOS_246 plasmid
            unnamed, complete sequence.
ACCESSION   NZ_CP020399
VERSION     NZ_CP020399.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:21:53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 354715
            Orig. end    :: 365531
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10816
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[359715:360531](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5816
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10816
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10816
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1616..1864)
                     /locus_tag="ctg3_300"
                     /transl_table=11
                     /translation="MQIEQTYRRLDISAPLSPLPANRAIAAVDVSTDDAERVADPGTGR
                     CLQIRRWVEALDAAQLTVVVGACKVAIDHDAHDVDDA"
     CDS             complement(1900..2355)
                     /locus_tag="ctg3_301"
                     /transl_table=11
                     /translation="MSKQLIVAVFGSADLARRAANDFDALSEKNEGFTIDNGVVVERDA
                     AGKLAVLDAQARPFRGGAIGAIAGALLGLLAGPLGVVTGFAAGAGAGVLADAAGSALLD
                     GRFVESVAATLAPASAAVILEAKEATPFSVDNVVTGFGGKVMRHALG"
     PFAM_domain     complement(1906..2166)
                     /aSDomain="DUF1269"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06897.14"
                     /description="Protein of unknown function (DUF1269)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_301_0024"
                     /evalue="2.40E-10"
                     /label="ctg3_301"
                     /locus_tag="ctg3_301"
                     /protein_end="150"
                     /protein_start="63"
                     /score="40.7"
                     /tool="antismash"
                     /translation="IGAIAGALLGLLAGPLGVVTGFAAGAGAGVLADAAGSALLDGRFV
                     ESVAATLAPASAAVILEAKEATPFSVDNVVTGFGGKVMRHAL"
     CDS             complement(2455..2646)
                     /locus_tag="ctg3_302"
                     /transl_table=11
                     /translation="MTTNANDFARAIDLQHAAEQAYRQARAAHDAAGAQPEPAAAMQAA
                     AARAYVDAARARERATGI"
     CDS             complement(2721..3173)
                     /locus_tag="ctg3_303"
                     /transl_table=11
                     /translation="MLNTSTVACSPAERIRRRFGHFLHAAELAGLIVIGLATAFAMAQE
                     AWKVVLAGEVSLTDLLLMFLYLEVLAMDVRYLRLGRLPVRFPLFIAMTSLARDLILRGA
                     TDSPARMLMTTFGIVLLALGVLILSFGQHRYPAEVGDVEDDVRASR"
     PFAM_domain     complement(2781..3092)
                     /aSDomain="PsiE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06146.14"
                     /description="Phosphate-starvation-inducible E family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_303_0025"
                     /evalue="7.10E-15"
                     /label="ctg3_303"
                     /locus_tag="ctg3_303"
                     /protein_end="131"
                     /protein_start="27"
                     /score="55.4"
                     /tool="antismash"
                     /translation="LAGLIVIGLATAFAMAQEAWKVVLAGEVSLTDLLLMFLYLEVLAM
                     DVRYLRLGRLPVRFPLFIAMTSLARDLILRGATDSPARMLMTTFGIVLLALGVLILSFG
                     "
     CDS             complement(3205..3534)
                     /gene_functions="regulatory (smcogs) SMCOG1031:LysR family
                     transcriptional regulator (Score: 66.3; E-value: 4.9e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_304"
                     /transl_table=11
                     /translation="MNLLEAMRIYVAVVEHGGLPGAASELKLAAAHVSDRIDGLERYLG
                     CRLLLRCADDGIACTDAGIAFHQCCVRTLSAVDDATADAGIRPPDAHVAEARRAAPHAL
                     HAARR"
     PFAM_domain     complement(3346..3525)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_304_0026"
                     /evalue="4.00E-12"
                     /label="ctg3_304"
                     /locus_tag="ctg3_304"
                     /protein_end="63"
                     /protein_start="3"
                     /score="46.0"
                     /tool="antismash"
                     /translation="LEAMRIYVAVVEHGGLPGAASELKLAAAHVSDRIDGLERYLGCRL
                     LLRCADDGIACTDAG"
     CDS             3964..5004
                     /locus_tag="ctg3_305"
                     /transl_table=11
                     /translation="METRPPLSQAVHSPITRSAIFLVATINPGDAHADTIRSWCGDIAA
                     LVRSVGKRVPGGNLSCVCGFGSDAWDALFGAPRPAALHPFREFGAGQRVAIATPGDILL
                     HIRADAMDLCFELATQLLAALGDAVTVVDEVHGFRNFDQRAMIGFVDGTENPEGRDAVD
                     FTVIGDEDAPFAGGSYVIVQKYLHDMAGWNALPVETQERIIGRTKLSDIELAPDVKPSS
                     SHSSLTTLDENGKEVKILRDNMPFGRPGAGEFGTYFIGYARSPAPIEQMLENMFVGRPP
                     GNYDRLLDFSRAVTGSLFFVPSADLLDALPDRAAPVEAAEAAPSSNEPHRDGSLKIGSL
                     KGVKSV"
     PFAM_domain     3988..4878
                     /aSDomain="Dyp_perox"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04261.14"
                     /description="Dyp-type peroxidase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_305_0027"
                     /evalue="3.40E-91"
                     /label="ctg3_305"
                     /locus_tag="ctg3_305"
                     /protein_end="305"
                     /protein_start="8"
                     /score="305.8"
                     /tool="antismash"
                     /translation="QAVHSPITRSAIFLVATINPGDAHADTIRSWCGDIAALVRSVGKR
                     VPGGNLSCVCGFGSDAWDALFGAPRPAALHPFREFGAGQRVAIATPGDILLHIRADAMD
                     LCFELATQLLAALGDAVTVVDEVHGFRNFDQRAMIGFVDGTENPEGRDAVDFTVIGDED
                     APFAGGSYVIVQKYLHDMAGWNALPVETQERIIGRTKLSDIELAPDVKPSSSHSSLTTL
                     DENGKEVKILRDNMPFGRPGAGEFGTYFIGYARSPAPIEQMLENMFVGRPPGNYDRLLD
                     FSRAVTGSLFFVPSAD"
     aSDomain        3991..4878
                     /aSDomain="TIGR01413"
                     /aSTool="tigrfam"
                     /description="Dyp_perox_fam: Dyp-type peroxidase family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_305_0007"
                     /evalue="3.60E-87"
                     /identifier="TIGR01413"
                     /label="ctg3_305"
                     /locus_tag="ctg3_305"
                     /protein_end="305"
                     /protein_start="9"
                     /score="290.6"
                     /tool="antismash"
                     /translation="AVHSPITRSAIFLVATINPGDAHADTIRSWCGDIAALVRSVGKRV
                     PGGNLSCVCGFGSDAWDALFGAPRPAALHPFREFGAGQRVAIATPGDILLHIRADAMDL
                     CFELATQLLAALGDAVTVVDEVHGFRNFDQRAMIGFVDGTENPEGRDAVDFTVIGDEDA
                     PFAGGSYVIVQKYLHDMAGWNALPVETQERIIGRTKLSDIELAPDVKPSSSHSSLTTLD
                     ENGKEVKILRDNMPFGRPGAGEFGTYFIGYARSPAPIEQMLENMFVGRPPGNYDRLLDF
                     SRAVTGSLFFVPSAD"
     PFAM_domain     5001..5753
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_306_0028"
                     /evalue="5.30E-95"
                     /label="ctg3_306"
                     /locus_tag="ctg3_306"
                     /protein_end="251"
                     /protein_start="0"
                     /score="317.6"
                     /tool="antismash"
                     /translation="MNNLHRELAPISSAAWEQIEEEVARTFKRSVAGRRVVDVEGPKGP
                     ELSAVGTGHLRDVAAPREHVDARLREVRTIVELTVPFELDRAAIDSVERGARDADWQAA
                     KEAAQRLAFAEDSAIFDGYPAAGIVGIREGTSNRKLTLPSDVGAYPDAISDALEALRLA
                     GVDGPYSVLLGADAYTALSEARDQGYPVIEHIKRIVSGEIVWAPAISGGCVLSTRGGDY
                     ELHLGEDVSIGYASHTDKVVRLYLRETLT"
     CDS             5001..5816
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_306"
                     /sec_met_domain="Linocin_M18 (E-value: 4.2e-96, bitscore:
                     315.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLHRELAPISSAAWEQIEEEVARTFKRSVAGRRVVDVEGPKGP
                     ELSAVGTGHLRDVAAPREHVDARLREVRTIVELTVPFELDRAAIDSVERGARDADWQAA
                     KEAAQRLAFAEDSAIFDGYPAAGIVGIREGTSNRKLTLPSDVGAYPDAISDALEALRLA
                     GVDGPYSVLLGADAYTALSEARDQGYPVIEHIKRIVSGEIVWAPAISGGCVLSTRGGDY
                     ELHLGEDVSIGYASHTDKVVRLYLRETLTFLMLTSEASVAVAPAAGTAA"
     CDS             5919..6188
                     /locus_tag="ctg3_307"
                     /transl_table=11
                     /translation="MSDTNDAMQKLQAAVDGLKQTVDANAGSRAAEVAVLFTVVSLMLA
                     ELPPDTRNLIEDSFSVWADGLSDAALSASVKQIARQRLAMTFDA"
     CDS             6228..6872
                     /locus_tag="ctg3_308"
                     /transl_table=11
                     /translation="MQAALFVAACAAHSGCAARAPAPDTPATAAAARRRALALALRFPA
                     RIVRPAPPPGALRAEVAARAARAAWRRLSPRPAPRPPVRSCARASVLLAARVRAHARVQ
                     FADGPTRNCVLDGLRRFAILNAVEVEPRAPRSARVRGAERRRRLPRRALRDGTGAERAP
                     PRRAACRGQHVPLPPRIGTSPFDPLSLTGARPPCPHFATSVTPGPPLRAPP"
     CDS             6815..9667
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     998.2; E-value: 5.1e-302)"
                     /gene_kind="other"
                     /locus_tag="ctg3_309"
                     /transl_table=11
                     /translation="MPALCDICHARPAVARATVMQDGERKTISICDYHFRQLMRHQSML
                     NPFDSLLGGGPSSLFGGLGEASPLAAEIPRESVDPTDAFSEQTLELLQRAAEKAHELRR
                     NELDTEHLLYALADTDVCAALLKELKLSPQDIKAYIDEHAHTGNADPDQSLEKLSISPR
                     VKKAVQYAFQASRDLGHSYIGPEHLLIGLASVPDSIAGTLLKKYGVTPEALRQKVVKVV
                     GKGAEDGRVDTPTGTPNLDKFGRDLTALARQGKLDPVLGRAQEIENAIEVLARRKKNNP
                     VLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRGKRLVEVNINSMVAGAKYRGEFEERAKQ
                     LIDEVTAKQDELILFIDELHTIVGAGQGGGEGGLDIANVLKPALARGELSLIGATTLNE
                     YQKYIEKDAALERRFQPVFVPEPSVEQTIVILRGLRDSLEAHHQVTFSDDAFVAAAEFA
                     DRYITSRFLPDKAIDLIDQAAARVRIGATSRPVDIQEDEAQIAQLKREQDYATSRKRFD
                     EAKQFEERINAKQKALDEKMEAWQRKTGSETLEVTVESVAEVVSRLTGIPVSELTQEER
                     QKLLKMEEQLRERVVGQNDAVVAVSDAVRLSRAGLGQTHRPIATFLFLGPTGVGKTELA
                     KALAESVFGDEQAIIRIDMSEYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVI
                     LLDEIEKAHPDVYNVLLQVFDDGRLTDGKGRVVDFSNTIIIATSNLGAAIIMDNLTQPE
                     AARKTDKAIREELMQVLKGHFRPEFLNRIDEVIVFHALSKENIRSIVQIQLDRVVRTAA
                     AQDIQLVMGESLIEHLTEAGYQPEFGARELKRQVRQTIETRLAKEILADALKSGDRVEV
                     DYDKGRGEVTFNKLAPDEAKDAKAAKQAGNGSAKGNGSAAAADGRPDGEAGASDGAPAE
                     VPPPAKKSGKKSSGAKKDAP"
     PFAM_domain     7097..7240
                     /aSDomain="Clp_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02861.22"
                     /description="Clp amino terminal domain, pathogenicity
                     island component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_309_0029"
                     /evalue="4.80E-06"
                     /label="ctg3_309"
                     /locus_tag="ctg3_309"
                     /protein_end="142"
                     /protein_start="94"
                     /score="26.7"
                     /tool="antismash"
                     /translation="AAEKAHELRRNELDTEHLLYALADTDVCAALLKELKLSPQDIKAY
                     IDE"
     PFAM_domain     7325..7483
                     /aSDomain="Clp_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02861.22"
                     /description="Clp amino terminal domain, pathogenicity
                     island component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_309_0030"
                     /evalue="5.80E-16"
                     /label="ctg3_309"
                     /locus_tag="ctg3_309"
                     /protein_end="223"
                     /protein_start="170"
                     /score="58.5"
                     /tool="antismash"
                     /translation="AFQASRDLGHSYIGPEHLLIGLASVPDSIAGTLLKKYGVTPEALR
                     QKVVKVVG"
     PFAM_domain     7658..8059
                     /aSDomain="AAA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00004.31"
                     /description="ATPase family associated with various
                     cellular activities (AAA)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_309_0031"
                     /evalue="3.30E-14"
                     /label="ctg3_309"
                     /locus_tag="ctg3_309"
                     /protein_end="415"
                     /protein_start="281"
                     /score="53.5"
                     /tool="antismash"
                     /translation="VLIGEPGVGKTAIVEGLAQRIVNGDVPEVLRGKRLVEVNINSMVA
                     GAKYRGEFEERAKQLIDEVTAKQDELILFIDELHTIVGAGQGGGEGGLDIANVLKPALA
                     RGELSLIGATTLNEYQKYIEKDAALERRFQ"
     PFAM_domain     8081..8383
                     /aSDomain="AAA_lid_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17871.3"
                     /description="AAA lid domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_309_0032"
                     /evalue="1.40E-30"
                     /label="ctg3_309"
                     /locus_tag="ctg3_309"
                     /protein_end="523"
                     /protein_start="422"
                     /score="105.4"
                     /tool="antismash"
                     /translation="SVEQTIVILRGLRDSLEAHHQVTFSDDAFVAAAEFADRYITSRFL
                     PDKAIDLIDQAAARVRIGATSRPVDIQEDEAQIAQLKREQDYATSRKRFDEAKQFE"
     PFAM_domain     8660..9169
                     /aSDomain="AAA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07724.16"
                     /description="AAA domain (Cdc48 subfamily)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_309_0033"
                     /evalue="1.90E-54"
                     /label="ctg3_309"
                     /locus_tag="ctg3_309"
                     /protein_end="785"
                     /protein_start="615"
                     /score="184.4"
                     /tool="antismash"
                     /translation="RPIATFLFLGPTGVGKTELAKALAESVFGDEQAIIRIDMSEYMER
                     HAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVYNVLLQVFDDGRL
                     TDGKGRVVDFSNTIIIATSNLGAAIIMDNLTQPEAARKTDKAIREELMQVLKGHFRPEF
                     LNRIDEV"
     PFAM_domain     9185..9427
                     /aSDomain="ClpB_D2-small"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10431.11"
                     /description="C-terminal, D2-small domain, of ClpB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_309_0034"
                     /evalue="4.10E-20"
                     /label="ctg3_309"
                     /locus_tag="ctg3_309"
                     /protein_end="871"
                     /protein_start="790"
                     /score="71.7"
                     /tool="antismash"
                     /translation="LSKENIRSIVQIQLDRVVRTAAAQDIQLVMGESLIEHLTEAGYQP
                     EFGARELKRQVRQTIETRLAKEILADALKSGDRVEV"
ORIGIN
        1 gagaacatgt agccgggccc gatcgtgatg ccttcgtcga gcgcgagctg atacagccgc
       61 atcgcgtcga cttgcgcggg caactcgatc cacaacacgt agccgcccgc cgggctcgag
      121 atgcgcgtgc cttccggaaa gaaacgcgac accatcgcgc gcatcaggtt cgcctgctgc
      181 gcataggcct tgcgcaagcg ccgcaggtga tgctcgtagc cgtcgcgttc gagaaactcg
      241 gcaatcgcga gttgcggcag cgacggtgtt gcgagcgtgt tcaggaattt gagtttctcg
      301 acctgttcac gatagcgccc cggcagcgcc catccgatcc ggtacgcggc cgtcaggctc
      361 ttcgagaacg acgagcaatg caagacgatg ccttcccggt cgaacgattt gagcgcgctc
      421 ggatgcgcat tgccgaaata cagttcgttg tacacgccgt tttcgatcag cggcatgttc
      481 acgcgcgtcg cgaattcgac cagctcgcgc ttgcgctcgt ccggcatctg aaagcccaac
      541 gggttctgga agttcggcat caccatgcac gcggcgatcg gctgcgattt cgcgatcgcc
      601 gccagcgccg cgatgtcgat gccgtattcc ggatgcgtcg caacctcgat cgccttcatc
      661 cccagtcgct cgatcgcatg cagcatcgcg tagaacgtcg gcgactccac ggcaatcgtg
      721 tcgcccggtt tcgcgaccgc ctgcagacag agattgatcg cctccgtcgc gcccaccgtc
      781 acgatgatct cgttcggatc gaccgacatg ccgttttcga ggtagcgccg tgcgatctgc
      841 cggatcagcc gcggatggcc gggcggcagc ccgtcggtca cgccccacag cgacttgtcg
      901 cgcccggccg catacgcgta gcggttcagc ttctcgaacg gaaacaggct cgggtccgga
      961 tacggcgagc cgagcggcac cgcgtcgtcc gtgccgatcg agcgcagcgt cgacagcacg
     1021 agccggctca cgtcgaccga cgacgaaatc gcgatcggct tcgacggacg cagttcgcgt
     1081 accggcgcat gcgcgtcgtc gcggcgcagg ttcacgaagt agcccgactg cggccgactt
     1141 tcgagcaacc cgcggctttc gagcagcagg tacgcatgca gcacggtcgt gatgctgatc
     1201 cgatgctgct ggcttgcctg ccgcaccgac ggcacacgat cgccgtgccg gtacacgcct
     1261 tgccgaatga gtctctcgat gtcgttcgca aacttctcgt agagcttcat ccgcctcgcc
     1321 tcgtcggcga tgatcggacg ggccccgcgt cggcgcgcgg cgcgcgcctg catcgtcgca
     1381 cgaggccgga aagccgcgca cggcccgcgg catgcgggct cgggcatcgt ccagtaccgt
     1441 aagtgaaggc gggtagcaat gcggattcca tcgtgacaag gatcggcatc ctactgcgtc
     1501 aattcggcga atgtaagtga cagtttcgcg ggccgacgcg aatttcatcg ggtgtaatga
     1561 acagatcggc gcaccgcgcg acgccttcgt tgccgcgcga tgcgcacgcg tgcgctcacg
     1621 cgtcgtcgac gtcgtgcgcg tcgtggtcga tcgcgacctt gcatgcgccg acgacgaccg
     1681 tcagctgcgc cgcgtcgagc gcttcgaccc atcggcgaat ctgcaggcac cggccggtgc
     1741 cgggatcggc gacgcgttcg gcatcgtcgg tgctcacgtc gacggccgcg atcgcgcggt
     1801 tggccggcag cggcgacagc ggcgccgaga tgtccaagcg ccggtatgtc tgttcgatct
     1861 gcatcgcttc ctcgcgatcg gcatgcatcg acgccgtgct cagccgagcg cgtggcgcat
     1921 caccttgccg ccgaatcccg tcacgacgtt gtcgaccgag aacggcgtcg cctccttcgc
     1981 ctcgagaatc acggcggcgc tggcgggtgc gagcgtcgcc gcgaccgatt cgacgaagcg
     2041 gccgtcgagc agcgcgctgc ccgccgcatc ggcgagcacg cccgcgcccg caccggcggc
     2101 gaagcctgtc acgacgccca gcgggcccgc gagcaggccg agcagcgcgc cggcgatcgc
     2161 gccgatcgcg ccgccgcgaa acggccgcgc ctgggcgtcg agcaccgcga gcttgccggc
     2221 cgcatcgcgt tcgacgacga caccgttgtc gatcgtgaat ccttcgttct tctccgacaa
     2281 cgcgtcgaaa tcgttcgccg cgcgtcgggc caggtccgcg ctgccgaata cggcaacgat
     2341 cagttgcttg ctcatccgat ccccctcgtt tgcaaggcgc gccccgccgc ggcgcgacgg
     2401 ttcggcgcgg gcgcttgccg gccggcgcga agcagccgcg cggccggcgt gcgttcagat
     2461 gccggttgcg cgttcgcggg cgcgtgcggc atcgacatac gcacgtgcgg ccgcggcctg
     2521 catcgccgca gccggttcag gctgcgcgcc ggccgcgtcg tgcgcagcgc gcgcctgccg
     2581 gtacgcctgc tcggccgcgt gctgcaagtc gatcgcgcgc gcgaagtcgt tcgcgttcgt
     2641 cgtcatgcgt gagcctccgt cgtgcgcgtc gcgccgcgac gccgtgccgt ttgccaaccg
     2701 aaagcttgcg cgtgcgtcga tcaccggctc gcacgcacat cgtcctcgac gtcgccgact
     2761 tcggccggat accggtgctg gccgaaactg aggatcagca cgccgagcgc gagcagcacg
     2821 atgccgaacg tcgtcatcag catccgcgcg gggctgtcgg tcgcgccgcg caggatcagg
     2881 tcgcgcgcga gcgacgtcat cgcgatgaac agcggaaagc gcaccggtag gcggccgagc
     2941 cgcagatagc gcacgtccat cgcgagcact tcgagataca ggaacatcag cagcaggtcg
     3001 gtcagcgaca cctcgcccgc gagcacgacc ttccacgcct cctgcgccat cgcgaacgcc
     3061 gtcgcgaggc cgatcacgat cagccccgcg agttcggccg catggagaaa atggccgaag
     3121 cggcggcgaa tgcgctcggc gggcgaacag gcgacggtgg acgtattcag catgtttcgt
     3181 gattcgatgg aaaacgcgcg cagctcagcg acgcgccgca tgcagcgcgt gcggcgcagc
     3241 gcggcgcgcc tcggcgacgt gtgcgtcggg cggccggatg ccggcatcgg ccgtcgcatc
     3301 gtcgacggcc gacagcgtgc gaacgcaaca ctgatgaaac gcgatgccgg catcggtgca
     3361 tgcgatgccg tcatcggcgc agcgcaacag cagacggcag ccgagatagc gttcgaggcc
     3421 gtcgatccgg tcgctcacgt gcgcggcggc gagcttcagt tcggacgccg caccgggcag
     3481 tccgccgtgc tcgaccaccg caacatagat gcgcatcgct tcaagcagat tcatcgtcgt
     3541 gctcctcgtc ggcggccgag cgaacccaat ctactgcacg ccacctgcac aaacaagagc
     3601 acagccgcgc gtgcggcagg agtacagccg cgcatcggca cgatggattc ggtgcatggt
     3661 ttgcgcattc gcaggacaga tcggcgatac gtgttccaaa gactcgccga agctgctaga
     3721 ttgcaggctc gaccgcgcga tgcgaagcga acgtcgcgca ccgggcgcat gcgccgcgcc
     3781 cgcgtgcatc gcttttccgc atgcgcggcg attgcgccgc attgcgcgtt gcgaccgtac
     3841 gcagcgcgtt tcatccgcat gtcatacaag agaacagtcg catgaccgag ttcatccgtt
     3901 tccgttcgcg cgccgcggca gccgcgcgcc gtccttcccg acatgactga ccggcaggcc
     3961 gcgatggaaa cacgtccccc gctctcccag gccgtccaca gtccgatcac gcgcagcgcg
     4021 atctttctcg tcgcgacgat caatcccggc gacgcgcatg ccgacacgat ccgctcgtgg
     4081 tgcggcgaca tcgccgcgct tgtgcgctcg gtcggcaagc gcgtgccggg cggcaacctg
     4141 tcgtgcgtct gcggcttcgg ctcggacgca tgggacgcgc tgttcggcgc accgcgtccc
     4201 gcggcattgc atccgttccg cgaattcggc gccggccagc gcgtcgcgat cgcgacgccc
     4261 ggcgacatcc tgctgcacat tcgcgccgat gcgatggacc tctgcttcga gctcgcgacg
     4321 caactgctcg ccgcgctcgg cgatgcggtg accgtcgtcg acgaagtgca cggctttcgc
     4381 aacttcgacc agcgcgcgat gatcggcttc gtcgacggca ccgagaatcc ggaaggccgc
     4441 gatgcggtcg acttcacggt gatcggcgac gaggatgcgc cgttcgccgg cggcagctac
     4501 gtcatcgtgc agaagtacct gcacgacatg gccggctgga acgcgctgcc ggtcgagacg
     4561 caggagcgca tcatcggccg cacgaagctg tccgacatcg agctggcgcc ggacgtgaag
     4621 ccgtcgtcgt cgcacagctc gctgacgacg ctcgacgaga acggcaagga agtgaagatc
     4681 ctgcgcgaca acatgccgtt cggccggccg ggcgccggag aattcggcac ttatttcatc
     4741 ggctatgcgc gctcgccggc accgatcgag cagatgctcg agaatatgtt cgtcggccgc
     4801 ccgccgggca actacgaccg gctgctcgat ttcagccgcg cggttaccgg ctcgctgttc
     4861 ttcgtgccgt cggccgacct gctcgacgcg ctgcccgacc gcgccgcacc cgtcgaggcc
     4921 gcggaggccg ccccgtcatc gaacgagccg caccgcgacg gctcgctgaa aatcggatcg
     4981 ctcaaaggag tcaaaagcgt atgaacaatc tgcaccgcga actcgcgccg atctccagcg
     5041 ccgcctggga gcaaatcgag gaagaagtcg cgcgcacctt caagcgttcg gtggccggcc
     5101 gccgcgtggt cgacgtcgaa ggcccgaagg ggcccgaact ctcggccgtc ggcaccgggc
     5161 acctgcgcga cgtcgcggcg ccgcgcgagc acgtcgatgc gcggctgcgc gaggtgcgca
     5221 cgatcgtcga gctgacggtg ccgttcgaac tcgaccgcgc cgcgatcgac agcgtcgagc
     5281 gcggtgcacg cgacgccgac tggcaggcgg ccaaggaagc cgcgcagcga ctcgcgttcg
     5341 cggaagacag cgcgatcttc gacggctatc cggccgccgg catcgtcggg atccgcgaag
     5401 gcacgtcgaa ccgcaagctc acgctgccga gcgacgtcgg cgcctatccg gacgccatca
     5461 gcgatgcgct cgaggcgctg cgcctcgcgg gcgtcgacgg cccgtactcg gtgctgctcg
     5521 gcgccgacgc ctataccgcg ctcagcgagg cgcgcgatca gggctatccg gtcatcgagc
     5581 acatcaagcg gatcgtcagc ggcgagatcg tctgggcgcc ggcgatcagc ggcggctgcg
     5641 tgctgtcgac gcgcggcggc gattacgagc ttcatctcgg cgaagacgtg tcgatcggct
     5701 atgcgagcca caccgacaag gtcgttcgcc tgtatctgcg cgaaaccttg acgttcctga
     5761 tgctgacgag cgaagcgtcg gtcgcggtcg cgccggctgc cggcacggcc gcctgatgcg
     5821 ccgcccgcgc gcgatgccgg cccggcgtcg cgcgctttgc ggccgcaccg cggccgcccg
     5881 ttcgtcgccg atcgaaccca tcccgcatgg agggaatcat gagcgatacg aatgatgcaa
     5941 tgcagaagct gcaagccgcc gtcgacgggc tgaagcaaac cgtcgacgcc aacgccggca
     6001 gccgggccgc cgaggtcgcc gtgctgttca ccgtcgtgtc gctgatgctg gccgaactgc
     6061 cgcccgacac gcgcaatctg atcgaagatt ccttttccgt atgggccgac ggtctgtcgg
     6121 acgccgcgtt gtccgcgagc gtcaagcaga tcgcgcgaca gcggctcgcg atgacgttcg
     6181 acgcgtgacg ccgccgcgtc gcgcgcgagc gccggccggc tcgcgccatg caagccgccc
     6241 tcttcgtcgc cgcttgcgcg gcgcacagcg gttgcgccgc ccgcgcgccc gcccctgaca
     6301 caccggccac cgcagccgcc gcgcgccgtc gcgcgctcgc gctcgcgctg cggtttcccg
     6361 cgcgcatcgt ccgccccgca ccgccgcccg gcgcgttgcg cgccgaggtc gcggcacgcg
     6421 ccgcacgcgc cgcctggcgc cgcctttccc ctcgtcctgc gccgcgcccg cccgtgcgga
     6481 gctgcgcacg cgcgtctgta ctcctcgcgg cccgcgttcg cgcgcatgcg agggtgcaat
     6541 ttgccgacgg accgacacgg aactgtgtct tggatggctt gcggcgattc gctattttga
     6601 acgcagtcga agtcgagccg cgggctccac gaagcgcgcg cgtacgcggt gccgaacgcc
     6661 gtcgccggct gccgcgtcgc gcgctgcgcg acggtacggg cgccgagcgc gcgccgccgc
     6721 gccgcgccgc gtgtcgcggt cagcacgttc cgttgccgcc acgcatcggg acgtcgccct
     6781 tcgatccact ttcattgaca ggagccagac caccatgccc gcactttgcg acatctgtca
     6841 cgcccggccc gccgttgcgc gcgccaccgt gatgcaggac ggcgaacgca agacgatctc
     6901 gatctgcgac tatcacttcc ggcagctgat gcgccatcag agcatgctga atccgttcga
     6961 ctcgctgctc ggcggcggtc cgtcgtcgct gttcggcggc ctcggcgaag catcgccgct
     7021 cgccgcggaa atcccgcgcg aatcggtcga tccgaccgac gcgttcagcg agcagacgct
     7081 cgagctgctg cagcgcgcgg ccgagaaggc acacgagctg cgccgcaacg aactcgacac
     7141 cgaacacctg ctgtacgcgc tcgccgacac cgacgtatgc gcggcactgc tgaaggaact
     7201 gaagctgtcg ccgcaggaca tcaaggccta catcgacgaa catgcgcaca ccggcaacgc
     7261 cgatccggac cagtcgctcg agaagctgtc gatctcgccg cgcgtgaaaa aggccgtgca
     7321 gtacgcgttc caggcgtcgc gcgatctcgg ccattcgtac atcgggcccg agcatctgct
     7381 gatcgggctc gcatcggtgc cggacagcat cgccggcacg ctgctgaaga aatacggcgt
     7441 gacgcccgag gcgctgcgcc agaaggtcgt gaaggtcgtg ggcaagggcg ccgaagacgg
     7501 ccgcgtcgac acgccgaccg gcacgccgaa tctcgacaag ttcggccgcg acctgaccgc
     7561 gcttgcacgc cagggcaagc tcgaccccgt gctcggccgc gcgcaggaaa tcgaaaacgc
     7621 gatcgaggtg ctcgcgcgcc gcaagaagaa caaccccgtg ctgatcggcg agccgggcgt
     7681 cggcaagacg gcgatcgtcg aagggctcgc gcagcggatc gtcaatggcg acgtaccgga
     7741 agtgctgcgc ggcaagcgcc tcgtcgaggt caacatcaat tcgatggtcg ccggcgcgaa
     7801 atatcgcggc gagttcgagg agcgcgcgaa gcagctgatc gacgaggtca ccgcgaagca
     7861 ggacgaactg atcctgttca tcgacgagct gcatacgatc gtcggcgcgg ggcaaggcgg
     7921 cggcgaaggc gggctcgaca tcgccaacgt gctgaagccg gcactcgcgc gcggcgagct
     7981 gagcctgatc ggcgcgacga cgctgaacga ataccagaag tacatcgaga aggatgcggc
     8041 gctcgagcgg cgcttccagc ccgtattcgt gccggagccg agcgtcgagc agacgatcgt
     8101 gatcctgcgc ggtctgcgcg acagcctcga agcgcaccac caggtcacgt tctccgacga
     8161 cgcgttcgtc gccgccgccg aattcgcgga ccgctacatc acgtcgcgct ttctgcccga
     8221 caaggcgatc gacctgatcg atcaggcggc cgcgcgcgtg cggatcggcg cgacctcgcg
     8281 cccggtcgac atccaggaag acgaagcgca gatcgcgcag ctcaagcgcg agcaggacta
     8341 cgcgacctcg cgcaagcgct tcgacgaggc gaagcagttc gaagaacgga tcaacgcgaa
     8401 acagaaggcg ctcgacgaga agatggaagc gtggcagcgc aagaccggct ccgagacgct
     8461 cgaggtcacg gtcgaatcgg tcgccgaggt cgtctcgcgc ctgaccggca ttccggtgtc
     8521 cgaactcacg caggaagagc gtcagaagct gctgaagatg gaagagcagc tgcgcgagcg
     8581 cgtggtcgga cagaacgacg cggtggtcgc ggtcagcgat gcggtgcgcc tgtcgcgcgc
     8641 ggggctcggt cagacgcatc ggccgatcgc gacgtttctg ttcctcgggc cgaccggcgt
     8701 cggcaagacc gagctcgcga aggcgctcgc cgaaagcgtg ttcggcgacg agcaggcgat
     8761 catccggatc gacatgtccg aatacatgga gcggcacgcg gtcgcacggc tgatcggcgc
     8821 gccgcccggc tacgtcggct acgacgaagg cggtcagctg accgagcgcg tgcggcgccg
     8881 cccgtacagc gtgatcctgc tcgacgagat cgagaaggcg catccggacg tctacaacgt
     8941 gctgctgcag gtgttcgacg acggccggct caccgacggc aagggacgcg tcgtcgactt
     9001 cagcaacacg atcatcatcg cgacgagcaa cctcggcgcg gcgatcatca tggacaacct
     9061 cacgcagccg gaagccgcgc gcaagaccga caaggcgatc cgcgaagaac tgatgcaggt
     9121 gctgaagggc cacttccgcc ccgagttcct gaaccggatc gacgaagtga tcgtgttcca
     9181 tgcgctgtcg aaggagaaca tccgctcgat cgtgcagatc cagctcgatc gcgtcgtacg
     9241 caccgcggcc gcgcaggaca tccagctcgt gatgggcgaa tcgctgatcg agcatctgac
     9301 cgaagcgggc tatcagccgg aattcggcgc gcgcgaactg aagcgtcagg tgcggcagac
     9361 gatcgagacg cggctcgcga aggaaatcct cgcggacgcg ctgaaatccg gcgatcgcgt
     9421 cgaggtcgac tacgacaagg gccgcggcga agtgacgttc aacaagctgg cgccggacga
     9481 ggcgaaggat gcgaaggccg ccaagcaggc cggcaacggc agcgcgaagg gcaacggcag
     9541 tgccgctgcc gccgacggcc ggcccgacgg cgaggccggc gcgagcgacg gcgcgccggc
     9601 cgaggtgccg ccgcccgcga agaagtccgg caagaaatcg tccggcgcga agaaggacgc
     9661 gccgtgaggc cccggccggt tgcgcggcgg cacgtcgccg cgcgcgccgg ccgccgatga
     9721 acccgcgcgg cccgacatcg gggcgcgcat gagcgtctgc gtccgccggg cgcagacgtc
     9781 cccgccgtcg cacggcgcaa cccgggctgc ccgcacggcg gcgcagctga tggagaatca
     9841 catgacaaat cgacgcgaag tgccaggcat caggaagtac gacgggcccg ccggcggttg
     9901 gggcgcgctt cgcgcgacag ccgaggccgt ccgcacgcag atggagacca tcgaggcacc
     9961 gatcacgctg atgcgcacca accagccgga cggcttcgac tgtcccggct gcgcgtggcc
    10021 ggacaaggag cacaagtcga cgttccagtt ctgcgagaac ggcgcgaaag ccgtcacgtg
    10081 ggaagcgacg accaagcgcg tgacgcccga gttcttcgcg gcgaatacgg tttcctcgct
    10141 gctgcgcatg tcggactacg agctcgagaa catgggtcgg ctcacgcatc cgctcgtcta
    10201 cgatcgcgcg accgacacgt tccgcgcggt cgaatgggac gacgcgttcg cgcgcatcgg
    10261 cgaagtgctg cgcgcgctgc cgcccgagca gatcgagttc tatacgtcgg gccgtgcctc
    10321 gaacgaggcc gcgtacctgt atcagctgtt cgcgcgcgaa ctcggcacga acaacttccc
    10381 cgactgctcg aacatgtgcc acgagccgac gagcgtcggg ctgccgcagt cgatcggcat
    10441 cggcaagggc accgtgtcgc tcgaggattt cgaccggtgc gagctgatca tctcgatcgg
    10501 ccacaatccc ggcacgaacc atccgcggat gatgggcacg ctgcacgaat gcgcgcgccg
    10561 ccacgtgccg atcatcgtgt tcaatccgct gcgcgagcgc gcgctcgaac gcttcgccga
    10621 tccgcaggac atgatcgaga tggcgtcgtt cggttcgacg cggatcgcat cgacgtacta
    10681 tcaggtcgat gcgggcggcg acgcggccgc gctgaagggc atcatgaagg cgctgctgca
    10741 gctcgaggcc gagcgcggcg acgtgctcga tcgcgcgttc atcgcgcagc acaccgaagg
    10801 cttcgacgca ttcgcg
//
