LOCUS       NZ_CP020398.1          10399 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP020398.1 Burkholderia multivorans strain FDAARGOS_246
            chromosome 2, complete sequence.
ACCESSION   NZ_CP020398
VERSION     NZ_CP020398.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:21:53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1335416
            Orig. end    :: 1345815
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10399
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[1340416:1340815](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5399
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     cand_cluster    1..10399
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10399
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="4"
                     /rules="ectoine_synt"
                     /tool="antismash"
     CDS             1134..1976
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091:glutamine-binding lipoprotein glnH (Score: 125.9;
                     E-value: 2.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_1143"
                     /transl_table=11
                     /translation="MSGQSSLRRFLRGALVPLAFAASLASAAPLQTVKPGTLLIGSDLT
                     YPPYAYLDGGKPAGFDAEFSRMLATHLKLEPVFLDTRFPDLILGMKARRFDVVASALYV
                     TPDRVKQVDFVPYLKTGASLLVAKGSAYRPKTPDELCGKRVGSIKGASWTPKLRAISTD
                     TCKPAGRGEIAILEFPTSPEATSALMSKAVDVQIEDAAVAQGIPKQTNGRVEPSSTTLL
                     YPIVIGLGVTKGDGGLQHALEGALNDAKRSGEYGSLVKKYGLQEPTAADVAAALGTAK"
     PFAM_domain     1248..1922
                     /aSDomain="SBP_bac_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00497.22"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1143_0112"
                     /evalue="2.60E-40"
                     /label="ctg2_1143"
                     /locus_tag="ctg2_1143"
                     /protein_end="263"
                     /protein_start="38"
                     /score="138.3"
                     /tool="antismash"
                     /translation="LIGSDLTYPPYAYLDGGKPAGFDAEFSRMLATHLKLEPVFLDTRF
                     PDLILGMKARRFDVVASALYVTPDRVKQVDFVPYLKTGASLLVAKGSAYRPKTPDELCG
                     KRVGSIKGASWTPKLRAISTDTCKPAGRGEIAILEFPTSPEATSALMSKAVDVQIEDAA
                     VAQGIPKQTNGRVEPSSTTLLYPIVIGLGVTKGDGGLQHALEGALNDAKRSGEYGSLVK
                     KYG"
     CDS             2071..3573
                     /gene_functions="transport (smcogs) SMCOG1096:polar amino
                     acid ABC transporter, inner membrane (Score: 187; E-value:
                     6.2e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_1144"
                     /transl_table=11
                     /translation="MQFDWHYALQLLWDKDFWRACVVVVKLSVSVWVFGVLLGFPVALA
                     RQSHQPALKRAAAAYIWFFRSLPLLVLLVFIYNLPQVFPATSTVLSDPFTAGLIAMVLS
                     ETAYFAEIHRGGILSVPRGQLEAGRALGIRFTGIQRMIVMPQAIRIALPALANEFITIV
                     KLTSLVSVISLAEILLVGQRLYTQNFLVFETMLAVAFYYVLIVTVFSRLLGYLERHLDV
                     SRRTAAQPAPASEALPLSAAAAAPRPRATAEFALRLKGIQQRYGRHEVLKDIHLDVAPG
                     QVVSIIGPSGSGKTSLIRTINGLAPLNAGEIELYGAPFIRAAGAHPPRVPNDRLLDIGM
                     VFQSFNLFPHRTALQNVMMAPCYHRQADTDAIRVQALSLLSKVGMLEHANKYPHQLSGG
                     QQQRVAIARALATRPSIMLFDEPTSALDPELVGEVLKVVETLAKEGMTMIIVTHEMNFA
                     FKVSDRIVFMENGRILYDVPPERIRASGDARVKDFLRHVHFA"
     aSDomain        2116..2415
                     /aSDomain="TIGR01726"
                     /aSTool="tigrfam"
                     /description="HEQRo_perm_3TM: amino ABC transporter,
                     permease protein, 3-TM region, His/Glu/Gln/Arg/opine
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_1144_0029"
                     /evalue="6.80E-21"
                     /identifier="TIGR01726"
                     /label="ctg2_1144"
                     /locus_tag="ctg2_1144"
                     /protein_end="115"
                     /protein_start="15"
                     /score="72.6"
                     /tool="antismash"
                     /translation="DFWRACVVVVKLSVSVWVFGVLLGFPVALARQSHQPALKRAAAAY
                     IWFFRSLPLLVLLVFIYNLPQVFPATSTVLSDPFTAGLIAMVLSETAYFAEIHRG"
     PFAM_domain     2173..2730
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1144_0113"
                     /evalue="1.90E-17"
                     /label="ctg2_1144"
                     /locus_tag="ctg2_1144"
                     /protein_end="220"
                     /protein_start="34"
                     /score="63.7"
                     /tool="antismash"
                     /translation="GVLLGFPVALARQSHQPALKRAAAAYIWFFRSLPLLVLLVFIYNL
                     PQVFPATSTVLSDPFTAGLIAMVLSETAYFAEIHRGGILSVPRGQLEAGRALGIRFTGI
                     QRMIVMPQAIRIALPALANEFITIVKLTSLVSVISLAEILLVGQRLYTQNFLVFETMLA
                     VAFYYVLIVTVFSRLLGYLERHL"
     PFAM_domain     2881..3342
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1144_0114"
                     /evalue="3.50E-30"
                     /label="ctg2_1144"
                     /locus_tag="ctg2_1144"
                     /protein_end="424"
                     /protein_start="270"
                     /score="105.4"
                     /tool="antismash"
                     /translation="LKDIHLDVAPGQVVSIIGPSGSGKTSLIRTINGLAPLNAGEIELY
                     GAPFIRAAGAHPPRVPNDRLLDIGMVFQSFNLFPHRTALQNVMMAPCYHRQADTDAIRV
                     QALSLLSKVGMLEHANKYPHQLSGGQQQRVAIARALATRPSIMLFDEPTS"
     CDS             3593..4939
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105:amidase (Score: 298.9; E-value: 1.2e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_1145"
                     /transl_table=11
                     /translation="MNGFDFPHDERRDARPCVDRLRACIARAAAHPDDIGTAWLARRDA
                     AALAEAHEWDRRARHGGAAPLAGAVLTVKACFDCEGWVTHAGSRVLADDPPARTDAAVV
                     AALRRAGAVLIAQTAMTEFAYGALGVNRTYGTPATPLDAHRERVAGGSSSGAAVSIALG
                     VADLSVGSDTSGSARIPAAFCGVAGFKPSRGRYPDAGMQFLSTTFDVPGLIAATAARCR
                     DADAALHGRAIGAAAPMPARIGDLHFVVPERFATDDTDAAVAQAFDAWLSRLSACGARI
                     ERKRLDCIVEAGAAAREGGIIAAEAFSLHRARLAACADRYDPLVAARITAGEQVRAHDY
                     AAALVRLRALADSYDAALGEADAVLTPTVPMLPPRMPELADTAVYLAQNARAFRLTEFA
                     NRLDLPSISVPADRRRNRPIGLLMTGRRGGDASLLDAAVRVEHALDACR"
     PFAM_domain     3653..4894
                     /aSDomain="Amidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01425.23"
                     /description="Amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1145_0115"
                     /evalue="8.30E-70"
                     /label="ctg2_1145"
                     /locus_tag="ctg2_1145"
                     /protein_end="434"
                     /protein_start="20"
                     /score="236.1"
                     /tool="antismash"
                     /translation="LRACIARAAAHPDDIGTAWLARRDAAALAEAHEWDRRARHGGAAP
                     LAGAVLTVKACFDCEGWVTHAGSRVLADDPPARTDAAVVAALRRAGAVLIAQTAMTEFA
                     YGALGVNRTYGTPATPLDAHRERVAGGSSSGAAVSIALGVADLSVGSDTSGSARIPAAF
                     CGVAGFKPSRGRYPDAGMQFLSTTFDVPGLIAATAARCRDADAALHGRAIGAAAPMPAR
                     IGDLHFVVPERFATDDTDAAVAQAFDAWLSRLSACGARIERKRLDCIVEAGAAAREGGI
                     IAAEAFSLHRARLAACADRYDPLVAARITAGEQVRAHDYAAALVRLRALADSYDAALGE
                     ADAVLTPTVPMLPPRMPELADTAVYLAQNARAFRLTEFANRLDLPSISVPADRRRNRPI
                     GLLMTGRRGGDASLL"
     PFAM_domain     5001..5378
                     /aSDomain="Ectoine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06339.14"
                     /description="Ectoine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1146_0116"
                     /evalue="1.80E-53"
                     /label="ctg2_1146"
                     /locus_tag="ctg2_1146"
                     /protein_end="126"
                     /protein_start="0"
                     /score="180.2"
                     /tool="antismash"
                     /translation="MIVVRSADIAHTERHASGPGWDSKRMIVKQDGVGYSVHETRVHEG
                     AELHLHYKHHFETNYCVAGEGEVVDTATGDVHRITPGTVYALNRNDAHILRATRGDLHL
                     VCVFNPPLTGRETHREDGSYAL"
     CDS             5001..5399
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1146"
                     /sec_met_domain="ectoine_synt (E-value: 4.4e-40, bitscore:
                     133.6, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVVRSADIAHTERHASGPGWDSKRMIVKQDGVGYSVHETRVHEG
                     AELHLHYKHHFETNYCVAGEGEVVDTATGDVHRITPGTVYALNRNDAHILRATRGDLHL
                     VCVFNPPLTGRETHREDGSYALPAGDDV"
     CDS             complement(5466..6140)
                     /gene_functions="regulatory (smcogs) SMCOG1071:GntR family
                     transcriptional regulator (Score: 126.8; E-value: 1.8e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_1147"
                     /transl_table=11
                     /translation="MASEKARGQSVADRISHQLREHIISGKLPPGTALIEMDLAAEYGT
                     SRNSLREVLHQLGREGLVTFVRHKGVVVRTLNRQDVRDLYVARRTLELHALNTAELAQP
                     VLLDKMQSAIRAAERELAKENWQAVGTHSLRFHQHIVALQKSALLDEFFRTISAQLRLV
                     FASDPDEKRVQTPDWIEREYRIYDLLTQNRRSEAVTVLARYLDDSERMLVDAIRRTHRD
                     AA"
     PFAM_domain     complement(5523..5894)
                     /aSDomain="FCD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07729.14"
                     /description="FCD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1147_0118"
                     /evalue="4.30E-11"
                     /label="ctg2_1147"
                     /locus_tag="ctg2_1147"
                     /protein_end="206"
                     /protein_start="82"
                     /score="43.4"
                     /tool="antismash"
                     /translation="DLYVARRTLELHALNTAELAQPVLLDKMQSAIRAAERELAKENWQ
                     AVGTHSLRFHQHIVALQKSALLDEFFRTISAQLRLVFASDPDEKRVQTPDWIEREYRIY
                     DLLTQNRRSEAVTVLARYLD"
     PFAM_domain     complement(5922..6107)
                     /aSDomain="GntR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00392.23"
                     /description="Bacterial regulatory proteins, gntR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1147_0117"
                     /evalue="2.20E-16"
                     /label="ctg2_1147"
                     /locus_tag="ctg2_1147"
                     /protein_end="73"
                     /protein_start="11"
                     /score="59.3"
                     /tool="antismash"
                     /translation="ADRISHQLREHIISGKLPPGTALIEMDLAAEYGTSRNSLREVLHQ
                     LGREGLVTFVRHKGVVV"
     CDS             complement(6214..7074)
                     /locus_tag="ctg2_1148"
                     /transl_table=11
                     /translation="MSSYPAAYQVTKGSVLNVDKSFYAAIAQRRDARERIESHVVPIRS
                     GFAWTVPAGHVFRIVTLEGPQVADLNMWNLHNPRERMWASRTRQLQAAHVTTFDRLWST
                     LPYLRPMATITDDTLADYGVDGDGGRVHDLLGTRCDPYVNKLLTGEDFHFHCHSNLVRA
                     VAPYGLTEFDVHDVLNVFQCTGLNDDDKYFMKACPAKPGDYLEFFAEIDLLCAMSTCPG
                     GDLSVPMWGPDARDPIDVCRPLGVEIYRLDSSLLAGWSSPAVAPYRGQHGMQPPQASWQ
                     HDGTA"
     PFAM_domain     complement(6433..6957)
                     /aSDomain="DUF1989"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09347.12"
                     /description="Domain of unknown function (DUF1989)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1148_0119"
                     /evalue="9.90E-68"
                     /label="ctg2_1148"
                     /locus_tag="ctg2_1148"
                     /protein_end="214"
                     /protein_start="39"
                     /score="227.1"
                     /tool="antismash"
                     /translation="VVPIRSGFAWTVPAGHVFRIVTLEGPQVADLNMWNLHNPRERMWA
                     SRTRQLQAAHVTTFDRLWSTLPYLRPMATITDDTLADYGVDGDGGRVHDLLGTRCDPYV
                     NKLLTGEDFHFHCHSNLVRAVAPYGLTEFDVHDVLNVFQCTGLNDDDKYFMKACPAKPG
                     DYLEFFAEIDLL"
     CDS             complement(7346..7870)
                     /locus_tag="ctg2_1149"
                     /transl_table=11
                     /translation="MRFRSYMAAGALALMPVLALAGQAATAPAAQPMFVNVNGQAVPVK
                     AETRVVQTAAGPMKVSTWSWHSPNGSASFEMQTSTGGMPPAAALRQIQAAELQMRAAQA
                     QMIAMQQQMMALQHVALANAFAMPMPQPVAFAMPMWAMPEPVVVLVPAQPPAKRPAAPA
                     VPAARGPQVSI"
     CDS             8211..9458
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 97.3; E-value:
                     1.2e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_1150"
                     /transl_table=11
                     /translation="MNPTLASARESNSPRFLLFLICLFASAGQLAIDIYVPALPDMARS
                     FATTPQAIQSSVSGYMAAYALGQLIFGPIADAYGRKRVLAFGLVIYTIGCLLSLGAPNL
                     ETFVLARCLQGFGIATTNLLAKAIITDSFSGQALMHAFTYMSIAWGLAPIVAPVIGAHL
                     QTWFGWRACLVFLLVYSLVMWALLWRYRETLPKPVHLEPRTLIANAGKVLASPVFQSCF
                     LAQGLCYSILLVFNIVGPFMVQNTLHQPPTFFGYLALGIGLMYFLGGLSNRIHGRGLPS
                     AEQRLRIGARAMACAAVAMLVLALTVGLRVWTLATPVLVMGFCAGAMYPTLMAKGNSLF
                     PHIAGLTSAILGCALLLVSSAMMGLAGFVSVQVLTPLALFFVALSFVVVWMVTKLLRYL
                     TQQQAATVACGSGETA"
     PFAM_domain     8271..9260
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1150_0120"
                     /evalue="1.40E-39"
                     /label="ctg2_1150"
                     /locus_tag="ctg2_1150"
                     /protein_end="350"
                     /protein_start="20"
                     /score="136.1"
                     /tool="antismash"
                     /translation="ICLFASAGQLAIDIYVPALPDMARSFATTPQAIQSSVSGYMAAYA
                     LGQLIFGPIADAYGRKRVLAFGLVIYTIGCLLSLGAPNLETFVLARCLQGFGIATTNLL
                     AKAIITDSFSGQALMHAFTYMSIAWGLAPIVAPVIGAHLQTWFGWRACLVFLLVYSLVM
                     WALLWRYRETLPKPVHLEPRTLIANAGKVLASPVFQSCFLAQGLCYSILLVFNIVGPFM
                     VQNTLHQPPTFFGYLALGIGLMYFLGGLSNRIHGRGLPSAEQRLRIGARAMACAAVAML
                     VLALTVGLRVWTLATPVLVMGFCAGAMYPTLMAKGNSLFPHIAGLTSAI"
     CDS             complement(9472..10161)
                     /locus_tag="ctg2_1151"
                     /transl_table=11
                     /translation="MNPLALRFIRSALSTGCAAALTTLAACNGDACFGLDVCFNDGTQP
                     VAVSGTAATGHALASAPVTVSCAQGSATTLTDGGGHYRVTVDATLPCVIAVTSGGTTLH
                     SLAYAGGTFNTTPETELLLVYLAAQLGTNTAGLIGNFQGTARYRQAMGSADAVQAAQSA
                     VVANLQQQYTVTLSTPTFLTTPFTVGQPGVDGDLDALAKAGAIDSTGMPAAAAVALLTQ
                     SGAAHPL"
ORIGIN
        1 cctcacggtg aaggagattc cgatcacgtc gcagaaccgg attccgctgc tgcagaacgg
       61 cacgatcgac ttcgaatgcg gatcgacgac gaacacgctc gaacggcaga agcaggccgc
      121 gttctcgaac agcatctttc tgtacggcat ccgcttcagc acgcggaagg actcgggcgt
      181 gaaggacttc ccggacctcg cgggcaagac ggtcgcgacg acggcgggca cgtcggacga
      241 gcggctgctg cgcaagctga acgaggagaa ggggatgaac atgacgatca tcagcgcgaa
      301 ggatcatgcg gaagcgttca tgaacgtgac gaccggccgc gccgtcgcgt tcgtgatgga
      361 cgagccgctg ctgtacggcg agatcgcgaa ggatcgcaat ccgggcgcct atacggtgac
      421 cggcacgccg ctgatgcacg agaactacgc gtgcatgatg cgcaaggacg atccggcgtt
      481 caagcgcgtc gtcgacggcg tgatcgcgaa gatgcagaca tccggtgaag cggagaagct
      541 ctacgatcgc tggttcatgc agccgatccc gccgaagggc gtgagcctga actatccgct
      601 gtcgccggag atgaagcagc tcttcaagaa tcctaccgat caggcgcagt actgattcgc
      661 acgcgctcgg cgcgtcgtat cgcatgcgtg cgccgttcgg cacgcacgac gcatgcgtcg
      721 tatgatcggc gaaacatcgc ggccgtccga tgccggtgcg gccgtctcac gatccgttgc
      781 atagcctgca acgcggcgcg cgcagcccgc gcgacgtcgc ttgccgatgc acgtgccgtt
      841 ccctccgcgc gacgcagctg aaccgccgat ccgcgtcgtg ttcacccatc gttgattccc
      901 ttttgttccc acacgcgccc gcacgccgcg cgatcgcatg catgcgcgca cgctccgcat
      961 gcccgcatcg ggtccgggcg taaacccgga ttcagatttc aatttgaact ggtcagaatc
     1021 ggccgaaatt gttcaacaat tttcggcgta aaaacctgcg gagccgcatg gggcggcgcg
     1081 caggcgcagt tgcgagccgt ttgcgcgata gccgaaaaat cgggagtcac gccatgtccg
     1141 gtcagtcttc gcttcgacgt ttccttcgcg gcgcgctcgt gccgctggct ttcgcggctt
     1201 cgctcgcatc ggcggcgccg ctgcagacgg tgaagcccgg cacgctgctg atcggctccg
     1261 atctcaccta tccgccgtac gcctatctcg acggcggcaa gccggccggc ttcgatgccg
     1321 agttctcgcg gatgctcgcg acgcatctga agctcgagcc ggtcttcctc gacacgcgct
     1381 ttcccgatct gattctcggc atgaaggcgc gccgcttcga tgtcgtcgcc tccgcgctgt
     1441 acgtgacgcc cgatcgcgtg aagcaggtcg acttcgtgcc gtacctgaag acgggcgcat
     1501 cgctgctcgt cgcgaagggc agcgcgtatc ggccgaaaac gcccgacgaa ctctgcggca
     1561 agcgcgtcgg ctcgatcaag ggcgcgtcgt ggacgccgaa gctgcgcgcg atctcgaccg
     1621 acacctgcaa gccggcgggc cgcggcgaaa tcgcgatcct cgaatttccg acgtcgccgg
     1681 aggcgacgtc cgcgctgatg tcgaaggccg tcgacgtgca gatcgaggac gcggccgtcg
     1741 cgcagggcat tccgaagcag acgaacgggc gtgtcgagcc gagctccacg acgctgctgt
     1801 atccgatcgt gatcggcctc ggcgtgacga agggcgacgg cgggctgcag cacgcgctcg
     1861 aaggtgcgct gaacgacgcg aagcgcagcg gcgaatacgg cagtctcgtg aagaagtacg
     1921 ggctgcagga gccgacggcc gccgacgtcg cggccgcgct cggcaccgcg aagtagccgc
     1981 acgcgttcgc gcgtacgccg cagcggcggc cgttcgcctc gcgcgatgcg cgggcggccg
     2041 ctttcccttc cgccggttga ggagtctccg atgcagttcg attggcacta tgcgttgcag
     2101 ctgttgtggg acaaggattt ctggcgcgca tgcgtcgtcg tcgtgaagct cagcgtgtcg
     2161 gtgtgggtgt tcggcgtgct gctcggcttt ccggtcgcgc tggcgcggca gtcgcatcag
     2221 ccggcgctca aacgcgctgc ggccgcttat atctggttct tccggagcct gccgctgctc
     2281 gtactgctcg tgttcatcta caacctgccg caggtgtttc ccgcgaccag caccgtgctg
     2341 tccgatccgt tcacggccgg cctgatcgcg atggtgctca gcgagacggc gtatttcgcg
     2401 gagatccatc gcggcggcat tctgtcggtg ccgcgcgggc agctcgaggc cggccgtgcg
     2461 ctcggcatcc gcttcaccgg catccagcgc atgatcgtga tgccacaggc gatccgcatc
     2521 gcgctgccgg cgctcgcgaa cgagttcatc acgatcgtga agctcacttc gctcgtgtcg
     2581 gtgatttcgc tcgccgagat tctgctcgtc ggccaacggc tgtacacgca gaacttcctc
     2641 gtgttcgaaa cgatgctggc cgtcgcgttc tactacgtgc tgatcgtcac ggtattcagc
     2701 cgtttgctcg gctatctcga acggcatctc gacgtcagcc gccgcacggc ggcgcagccg
     2761 gcgccggcga gtgaggcgct gccgctgtcg gcagcggccg ccgcgccacg gccgcgtgcg
     2821 accgccgagt tcgcactgcg gctcaagggc atccagcagc gctacggccg ccatgaagtg
     2881 ctgaaggaca ttcatctcga cgtcgcgccc gggcaagtcg tgtcgatcat cgggccgtcg
     2941 gggtccggca agacgtcgct gatccgcacg atcaatgggc tggcgccgct gaacgcgggc
     3001 gagatcgagc tgtacggcgc gccgttcatt cgtgcggcgg gcgcgcatcc gccgcgcgtg
     3061 ccgaacgacc gcctcctcga tatcggcatg gtgttccaga gcttcaacct gtttccgcat
     3121 cgcaccgcgc tgcagaacgt gatgatggcg ccgtgctatc accgccaggc cgataccgat
     3181 gcgatccgcg tgcaggcgct gtcgctgttg tcgaaggtcg ggatgctcga gcatgcgaac
     3241 aagtatccgc accagctgtc gggcggccag cagcagcgcg tcgcgattgc gcgtgcgctc
     3301 gcgacgcgcc cgtcgatcat gttgttcgac gagccgacgt cggcgctcga tccggagctg
     3361 gtcggcgaag tactgaaagt cgtcgagacg ctcgcgaagg aagggatgac gatgatcatc
     3421 gtcacgcacg aaatgaactt cgcgttcaag gtgtccgacc gcatcgtctt catggagaac
     3481 ggccgcatcc tctacgacgt gccgcccgag cgcatacggg cgagcggcga cgcacgcgtg
     3541 aaggattttc tgcggcatgt tcacttcgca tgatgggacg cgaggctcac gcatgaacgg
     3601 cttcgatttt ccgcacgacg aacggcgcga cgcgcgcccc tgcgtcgacc ggttgcgcgc
     3661 atgcattgcc cgtgcggccg cgcatccgga cgacatcggc accgcatggc tggcgcgtcg
     3721 cgacgcggcg gcgctcgccg aggcgcacga atgggaccgg cgcgcgcgtc acggcggcgc
     3781 cgcgccgctg gccggtgcgg tgctgacggt gaaggcgtgt ttcgactgcg aaggctgggt
     3841 cacgcatgca ggctcgcgcg tactcgccga cgatccgccg gcgcgcaccg acgcggcagt
     3901 ggtcgcggcg ctgcgacgcg ccggcgccgt gctcattgcg cagaccgcga tgacggagtt
     3961 cgcgtacggc gcgctcggcg tgaaccgcac ctacggcacg ccggcgacgc cgctcgacgc
     4021 gcatcgcgag cgcgtggcag gcgggtcgag ctcgggcgcc gcggtgtcga tcgcgctggg
     4081 cgtcgccgat ctgtcggtcg gctcggacac gagcggatcg gctcgcattc cggccgcatt
     4141 ctgcggcgtg gcggggttca agccctcgcg cggccgctat cccgatgcgg gcatgcaatt
     4201 cctgtcgacg acgttcgacg tgccaggcct gatcgccgcg acggccgcgc gatgccgcga
     4261 tgcggacgcc gcgctgcacg gccgtgcgat tggtgcggct gcgcctatgc ctgcgcgaat
     4321 cggcgacctg catttcgtcg tgccggaacg cttcgcgacc gacgacaccg atgcagcggt
     4381 cgcgcaggcg ttcgacgcgt ggctgtcgcg gctatccgcg tgcggcgcgc gcatcgagcg
     4441 caagcggctc gattgcatcg tcgaggccgg tgcggctgcg cgcgagggcg gcatcatcgc
     4501 ggccgaggcg ttcagtctgc atcgcgcgcg gctcgcggcg tgcgcggatc gctacgaccc
     4561 gctcgtcgcc gcacgcatca ctgcgggcga gcaggtgcgt gcgcacgact atgcggctgc
     4621 gctggtgcgt ctgcgcgcac tggccgactc gtacgacgcg gcgctcggcg aagcggacgc
     4681 ggtgctcacg ccgacggtgc cgatgctgcc gccgcgtatg cccgagctgg ccgacaccgc
     4741 cgtctatctc gcgcagaatg cgcgcgcatt ccggctcacc gagttcgcga accggctcga
     4801 tctgccgagc atcagcgtgc cggcggaccg ccggcggaac aggccgatcg ggctgctgat
     4861 gaccggacgc cgcggcggcg atgcaagcct gctcgatgcg gcagtgcgcg tcgaacacgc
     4921 gctggacgca tgcagatgaa ccgtttcccg tcggcggggc acgccctgcc gtttttcatc
     4981 gtcaccattc cgaggtgctc atgatcgtcg taagatcggc cgacattgcc cacaccgaac
     5041 gccacgcaag cgggcctggt tgggacagca agcggatgat cgtcaagcag gacggcgtcg
     5101 gctattccgt tcacgaaacg cgcgtgcacg aaggcgcgga gctgcatctg cattacaagc
     5161 atcacttcga gaccaactat tgcgtcgcag gcgaagggga ggtggtcgat acggcaaccg
     5221 gcgacgtgca ccgcatcacg ccgggcacgg tctacgcgct gaaccggaac gacgcgcaca
     5281 ttctgcgcgc gacgcgcggc gatctgcatc tggtctgcgt gttcaatccg ccgctgacgg
     5341 ggcgcgaaac gcatcgcgaa gacggcagct atgcgctgcc ggccggcgac gacgtgtaag
     5401 gctggcccgc cgtcgtcgca tgcgtgccgc atcgcgcggc atgcatgcgg cgtgcgctgc
     5461 gtgcgctacg cggcgtcgcg atgggtgcgg cggatcgcgt cgacgagcat gcgctcggaa
     5521 tcgtcgagat agcgtgcgag caccgtcacg gcttcgcttc ggcggttctg cgtgagcaga
     5581 tcgtagatgc ggtattcgcg ttcgatccag tcgggcgtct gcacgcgttt ctcgtcggga
     5641 tcggacgcga acacgagacg cagctgcgca gagatcgtcc ggaagaattc gtcgagcagc
     5701 gcggacttct gcagcgcgac gatatgctga tgaaaccgca ggctatgcgt gccgacggcc
     5761 tgccagttct ctttcgcgag ttcgcgctcg gccgcgcgga tcgccgattg catcttgtcg
     5821 agcagcaccg gttgcgcaag ctcggccgta ttgagcgcat gcagttcgag cgtgcggcgc
     5881 gcgacgtaca gatcgcgtac gtcctggcga ttgagcgtgc gcacgaccac gcccttgtgc
     5941 cgcacgaacg tgacgagccc ctcgcggcca agctgatgca ggacttcgcg aagcgaattg
     6001 cgcgacgtgc cgtattcggc ggcgaggtcc atctcgatca gcgcggtgcc gggcggcagc
     6061 ttgccgctga tgatgtgctc gcgcaattga tggctgatcc ggtcggcgac cgattgtcct
     6121 ctcgcttttt cgcttgccat gctgtccgtt cgctcctgtc cgatcgccgc cggcgtggcc
     6181 ggccggcggc gtttcgccat tctacgggct ttgtcacgcc gtgccgtcgt gctgccagct
     6241 cgcctgcggc ggctgcatcc cgtgctggcc gcgatacggc gcgacggccg gcgacgacca
     6301 gcctgcgagc aggctcgaat cgagccggta gatctcgacg ccgagcggcc ggcacacgtc
     6361 gatcggatcg cgtgcgtcgg gcccccacat cggcacggac agatcgccgc ccgggcacgt
     6421 cgacatcgca cacaacagat cgatctcggc gaagaactcc agatagtcgc ccggtttcgc
     6481 cgggcaggct ttcatgaagt atttgtcgtc gtcgttcagg cccgtgcact ggaacacgtt
     6541 cagcacgtcg tgcacgtcga attcggtcag cccgtacggc gcaaccgcgc gcacgaggtt
     6601 cgagtggcag tggaaatgga agtcctcgcc ggtcagcagc ttgttgacgt acggatcgca
     6661 gcgtgtgccg agcaggtcgt gcacacggcc gccgtcgccg tcgacgccgt agtcggcgag
     6721 cgtgtcgtcg gtgatcgtcg ccatcgggcg cagatacggc agcgtcgacc acaggcgatc
     6781 gaacgtcgtc acgtgcgccg cctgcaactg acgcgtgcgc gacgcccaca tccgctcgcg
     6841 cggattgtgc aggttccaca tgttcagatc ggcgacctgc ggcccctcga gcgtgacgat
     6901 ccggaacacg tggccggccg ggaccgtcca ggcgaacccg ctgcggatcg gcacgacgtg
     6961 cgattcgatg cgctcgcgcg cgtcgcgacg ctgcgcgatc gcggcataga acgatttgtc
     7021 gacgttcagg acggagcctt tggtgacctg gtaagcggcg ggatagctgg acatgacgcg
     7081 ttgctctcga cgaaggtggc ggatacgggc ggtcggccgg aagcctttgc agtggccggt
     7141 caggcgtcaa ttcggatggt ggattgttca acaatccgtt ggcgctgcga ggagtatagg
     7201 cggagggcgg ggccgcgtgt caaccggcgg aaagtaccga gaagtaccgc gcgcggcgcg
     7261 ggcgtgcagg cgcgctcgct gcgggaggag ataaaaaaac cgccggcacg cgccggcggt
     7321 tctggcatgc gatgcgtacg cagtgtcaga tgctgacctg cgggccgcgc gcggccggca
     7381 cggcgggtgc agccgggcgt ttcgcgggcg gctgcgccgg cacgagcacg acgaccggct
     7441 cgggcatcgc ccacatcggc atcgcgaagg cgaccggctg cggcatcggc atcgcgaacg
     7501 catttgcgag cgcgacatgc tggagcgcca tcatctgctg ctgcatcgcg atcatctgcg
     7561 cctgggcggc acgcatctgc agctcggcgg cctggatttg ccgcagcgcg gcggccggcg
     7621 gcatgccgcc ggtcgaggtc tgcatctcga agctcgcact gccgttcggg ctatgccagc
     7681 tccaggtgct gaccttcatc ggaccggcgg ccgtttgcac gacgcgcgtc tcggccttca
     7741 cgggcacggc ttgcccgttc acattgacga acatcggttg cgcggcgggg gccgttgctg
     7801 cctgaccggc cagagcgagg accggcatca gtgccagcgc gcccgccgcc atgtacgaac
     7861 ggaatcgcat agttgtttct ccatcgagcg aaactgatcg aatgacattc cacttcatcg
     7921 tgcggctcgc gcagcgagcc accgtgacta tgcgtcggca agcttaagtc agaattaaaa
     7981 atcgggacag gcgccgagcc gcggcggcat ggcggggcgc aagggctgcg ggcggggcga
     8041 tgcacgcacg gccggccgcc gcaatccggg ttcaaccgca ccggtgccag ggagaatcgc
     8101 atcgtgccgc gcaacaacag gcacaatacg cacccacgcg ccgcgcacac gtgttcgcat
     8161 ttcgaacgac gtggcgatgc gtcgccgccg ttcgaatcgt tcccgtcctc atgaatccca
     8221 cactcgcttc cgcgcgcgag tcgaactcgc cgcgcttcct gctgttcctg atctgcctgt
     8281 tcgcttccgc cggccagctc gcgatcgaca tctacgtgcc cgcgctgccc gacatggcac
     8341 gctcgttcgc gacgacgccg caggcgatcc agtcgagcgt gtcgggctac atggccgcgt
     8401 atgcgctcgg tcagctgatc ttcggcccga tcgccgacgc gtacggccgc aagcgcgtgc
     8461 tcgcgttcgg tctcgtcatc tatacgatcg gctgcctgct gtcgctcggc gcgccgaacc
     8521 tcgagacctt cgtgctcgcg cgctgtctgc agggcttcgg gatcgcgacg acgaacctgc
     8581 tcgcgaaggc gatcatcacc gattcgttct cggggcaggc gctgatgcac gcgttcacct
     8641 acatgtcgat cgcgtggggg ctcgcgccga tcgtcgcgcc ggtgatcggc gcgcatctgc
     8701 agacctggtt cggctggcgc gcgtgcctcg tgttcctgct cgtgtattcg ctcgtgatgt
     8761 gggcgctgct gtggcgctac cgggagacct tgccgaagcc cgttcatctc gagccgcgca
     8821 cgctgatcgc gaatgcgggc aaggtgctgg cgagcccggt attccagagc tgcttcctcg
     8881 cgcaaggcct gtgctacagc atcctgctcg tgttcaacat cgtcggaccg ttcatggtgc
     8941 agaacacgct gcaccagccg ccgacgttct tcggctatct cgcgctcggc atcgggctga
     9001 tgtatttcct cggcggcctg tcgaaccgga ttcacggacg cggcctgccg agcgccgagc
     9061 agcggttgcg catcggcgca cgcgcgatgg cgtgcgcggc cgtcgcgatg ctcgtgctcg
     9121 cgctgaccgt cggcctgcgc gtctggacgc tcgcgacgcc ggtgctcgtg atgggcttct
     9181 gcgcaggcgc gatgtatccg acgctgatgg ccaagggcaa ttcgctgttc ccgcatatcg
     9241 cggggctcac cagcgcgatt ctcggctgcg cgctgctgct cgtgtcgtcc gcgatgatgg
     9301 ggctcgccgg cttcgtctcg gtgcaggtgc tgacgccgct cgcgctgttc ttcgtcgcgc
     9361 tgtcgttcgt cgtcgtctgg atggtgacga agctgctgcg ctatctgacg cagcagcagg
     9421 ccgcgaccgt cgcatgcggg agcggcgaga ccgcgtaagc gcgcgcagcg ttcacagggg
     9481 atgcgccgcg ccggactgcg tcagcagcgc aacggccgcc gcagccggca tcccggtcga
     9541 gtcgatcgcg ccggcctttg cgagcgcgtc gagatcgccg tcgacgcccg gttgaccgac
     9601 cgtgaacggc gtcgtcagga acgtcggtgt cgagagcgtg acggtgtatt gctgctgcag
     9661 attcgcgacc actgccgatt gcgcggcctg caccgcgtcc gcgctgccca tcgcctgccg
     9721 atagcgtgcg gtgccctgga aattgccgat caggccggcc gtattcgtgc cgagctgcgc
     9781 ggccaggtag acgagcagca attccgtttc gggcgtcgtg ttgaaggtgc cgcccgcata
     9841 ggcgagggaa tgcagcgtcg tgccgcccga cgtcacggcg atcacgcagg gcagcgtcgc
     9901 gtcgacggtg acgcggtagt ggccgccgcc gtcggtcagc gtcgtcgccg agccttgcgc
     9961 gcaactgacg gtgaccggtg cgctggcgag cgcatggccg gtcgcggccg tgcccgacac
    10021 cgcgacgggc tgcgtgccgt cgttgaagca gacgtcgagg ccgaagcacg cgtcgccgtt
    10081 gcaggccgcg agcgtcgtca gcgcggcagc gcagccggtg ctcagcgcgg agcggatgaa
    10141 gcgcagggcg agagggttca tggtcgcgga cgctcgggga aaggggcagc cggagtgggg
    10201 cgcgcgtggc gccgctccta ttctatgtcc gggatgtgcg cgacgcttgt ctgtcttggc
    10261 ggcgacgcgc gatgcggcgt caggtaaccg aagcaagcgg cactgccgcc cacgccggca
    10321 cccggcttcg gcgcgcggcg cgcgaatgag ggatgaccaa aaaactcggc ggcggcgcgc
    10381 aatgcagcgt cgggcaacg
//
