Select genomic region:
Overview
1.1
1.2
2.1
2.2
2.3
2.4
2.5
2.6
2.7
3.1
3.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP020397.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS | 1,818,140 | 1,872,785 | ornibactin | NRP | 100%
Region 1.2 | terpene | 2,124,890 | 2,145,723 |

NZ_CP020398.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | terpene | 311,282 | 333,230 |
Region 2.2 | NRPS-like | 745,903 | 788,890 |
Region 2.3 | RiPP-like,hserlactone | 1,210,248 | 1,233,104 |
Region 2.4 | ectoine | 1,335,417 | 1,345,815 |
Region 2.5 | terpene | 1,628,214 | 1,649,269 |
Region 2.6 | arylpolyene | 1,708,180 | 1,753,058 | APE Vf | Other | 35%
Region 2.7 | phosphonate | 1,786,696 | 1,828,384 | phosphinothricintripeptide | NRP | 6%

NZ_CP020399.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | redox-cofactor | 137,489 | 159,624 | lankacidin C | NRP + Polyketide | 13%
Region 3.2 | RiPP-like | 354,716 | 365,531 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS | 1,818,140 | 1,872,785 | ornibactin | NRP | 100%
Region 1.2 | terpene | 2,124,890 | 2,145,723 |
Region 2.1 | terpene | 311,282 | 333,230 |
Region 2.2 | NRPS-like | 745,903 | 788,890 |
Region 2.3 | RiPP-like,hserlactone | 1,210,248 | 1,233,104 |
Region 2.4 | ectoine | 1,335,417 | 1,345,815 |
Region 2.5 | terpene | 1,628,214 | 1,649,269 |
Region 2.6 | arylpolyene | 1,708,180 | 1,753,058 | APE Vf | Other | 35%
Region 2.7 | phosphonate | 1,786,696 | 1,828,384 | phosphinothricintripeptide | NRP | 6%
Region 3.1 | redox-cofactor | 137,489 | 159,624 | lankacidin C | NRP + Polyketide | 13%
Region 3.2 | RiPP-like | 354,716 | 365,531 |

Compact view
NZ_CP020397.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,818,140 - 1,872,785 nt. (total: 54,646 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001721.1 |  | 0.66 | NRP | ornibactin | Burkholderia cepacia
BGC0000426.1 |  | 0.37 | NRP | sevadicin | Paenibacillus larvae
BGC0000389.1 |  | 0.35 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001479.1 |  | 0.33 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0000427.1 |  | 0.33 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0000901.1 |  | 0.33 | Other | ferrichrome | Aspergillus niger
BGC0000351.1 |  | 0.31 | NRP | exochelin | Mycolicibacterium smegmatis
BGC0001249.1 |  | 0.31 | NRP | dimethylcoprogen | Alternaria alternata
BGC0000348.1 |  | 0.31 | NRP | ergovaline | Epichloe festucae var. lolii
BGC0000410.1 |  | 0.31 | NRP | pseudomonine | Pseudomonas fluorescens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001721.1 |  | 0.87 | NRP | ornibactin | Burkholderia cepacia
BGC0000426.1 |  | 0.69 | NRP | sevadicin | Paenibacillus larvae
BGC0000389.1 |  | 0.68 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001479.1 |  | 0.67 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0000427.1 |  | 0.66 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0000901.1 |  | 0.66 | Other | ferrichrome | Aspergillus niger
BGC0000351.1 |  | 0.65 | NRP | exochelin | Mycolicibacterium smegmatis
BGC0001249.1 |  | 0.64 | NRP | dimethylcoprogen | Alternaria alternata
BGC0000348.1 |  | 0.64 | NRP | ergovaline | Epichloe festucae var. lolii
BGC0000410.1 |  | 0.64 | NRP | pseudomonine | Pseudomonas fluorescens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 1818139 - 1872785:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X - D-asp - ser) + (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1672: X - asp - ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (13..422): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAeAaGGisK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      60% (weak)
  AMP-binding (1085..1488): asp
  NRPSPredictor2: asp
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      asp, asn
    Single AA prediction:
      asp
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLTKVGHVGK
    Nearest Stachelhaus code:
      asp
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2614..3026): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHVSLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
ctg1_1673: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (518..923): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DGeYTGgitK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      60% (weak)

NZ_CP020397.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,124,890 - 2,145,723 nt. (total: 20,834 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000928.1 |  | 0.16 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.16 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0001227.1 |  | 0.13 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000527.1 |  | 0.12 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000515.1 |  | 0.10 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0000897.1 |  | 0.09 | Other | dehydrophos | Streptomyces luridus
BGC0001727.1 |  | 0.09 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000842.1 |  | 0.09 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus
BGC0000668.1 |  | 0.08 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001701.1 |  | 0.08 | RiPP | nisin O | Blautia obeum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000928.1 |  | 0.47 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.47 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0001227.1 |  | 0.42 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000527.1 |  | 0.39 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000515.1 |  | 0.35 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0000897.1 |  | 0.34 | Other | dehydrophos | Streptomyces luridus
BGC0001727.1 |  | 0.34 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000842.1 |  | 0.32 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus
BGC0000668.1 |  | 0.32 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0001701.1 |  | 0.30 | RiPP | nisin O | Blautia obeum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP020398.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 311,282 - 333,230 nt. (total: 21,949 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.28 | Terpene | carotenoid | Myxococcus xanthus
BGC0000630.1 |  | 0.24 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000656.1 |  | 0.24 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000640.1 |  | 0.23 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000646.1 |  | 0.21 | Terpene | β-carotein | uncultured bacterium
BGC0000643.1 |  | 0.20 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.20 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000635.1 |  | 0.18 | Terpene | carotenoid | Paracoccus sp. N81106
BGC0000642.1 |  | 0.18 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0000641.1 |  | 0.18 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.61 | Terpene | carotenoid | Myxococcus xanthus
BGC0000630.1 |  | 0.58 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000656.1 |  | 0.57 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000640.1 |  | 0.57 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000646.1 |  | 0.54 | Terpene | β-carotein | uncultured bacterium
BGC0000643.1 |  | 0.53 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.52 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000635.1 |  | 0.50 | Terpene | carotenoid | Paracoccus sp. N81106
BGC0000642.1 |  | 0.50 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0000641.1 |  | 0.49 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP020398.1 - Region 2 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 745,903 - 788,890 nt. (total: 42,988 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001900.1 |  | 0.34 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001168.1 |  | 0.33 | NRP | livipeptin | Streptomyces lividans 1326
BGC0001599.1 |  | 0.29 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001399.1 |  | 0.26 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000375.1 |  | 0.22 | NRP | indigoidine | Streptomyces chromofuscus
BGC0000343.1 |  | 0.22 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001591.1 |  | 0.22 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.22 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000427.1 |  | 0.21 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001964.1 |  | 0.21 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Cystobacterineae bacterium

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001900.1 |  | 0.67 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001168.1 |  | 0.66 | NRP | livipeptin | Streptomyces lividans 1326
BGC0001599.1 |  | 0.62 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001399.1 |  | 0.59 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000375.1 |  | 0.55 | NRP | indigoidine | Streptomyces chromofuscus
BGC0000343.1 |  | 0.54 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001591.1 |  | 0.54 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.54 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000427.1 |  | 0.54 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001964.1 |  | 0.54 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Cystobacterineae bacterium

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 745902 - 788890:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg2_652: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (14..404): X
  NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DiWfFafIfK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      50% (weak)

NZ_CP020398.1 - Region 3 - RiPP-like,hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,210,248 - 1,233,104 nt. (total: 22,857 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000817.1 |  |  | 0.16 | Alkaloid | methylarcyriarubin | uncultured bacterium
BGC0001964.1 |  |  | 0.16 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Cystobacterineae bacterium
BGC0001897.1 |  |  | 0.16 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000703.1 |  |  | 0.15 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001120.1 |  |  | 0.15 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000595.1 |  |  | 0.14 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  |  | 0.14 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000597.1 |  |  | 0.14 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0000993.1 |  |  | 0.12 | NRP, Polyketide | FR901228 | Chromobacterium violaceum
BGC0001343.1 |  |  | 0.11 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000817.1 |  | 0.47 | Alkaloid | methylarcyriarubin | uncultured bacterium
BGC0001897.1 |  | 0.46 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000703.1 |  | 0.45 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001120.1 |  | 0.45 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000595.1 |  | 0.44 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  | 0.44 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000597.1 |  | 0.44 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0001343.1 |  | 0.38 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001437.1 |  | 0.35 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.35 | NRP | obafluorin | Pseudomonas fluorescens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP020398.1 - Region 4 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 1,335,417 - 1,345,815 nt. (total: 10,399 nt) Show pHMM detection rules used
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000860.1 |  | 0.28 | Other | ectoine | Methylarcula marina
BGC0000859.1 |  | 0.27 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000858.1 |  | 0.27 | Other | ectoine | Methylobacter marinus
BGC0000854.1 |  | 0.27 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.27 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.27 | Other | ectoine | Methylomicrobium kenyense
BGC0000856.1 |  | 0.27 | Other | ectoine | Methylophaga thalassica
BGC0000853.1 |  | 0.27 | Other | ectoine | Streptomyces anulatus
BGC0000852.1 |  | 0.26 | Other | ectoine | Sporosarcina pasteurii
BGC0001526.1 |  | 0.17 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000860.1 |  | 0.61 | Other | ectoine | Methylarcula marina
BGC0000859.1 |  | 0.61 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000858.1 |  | 0.61 | Other | ectoine | Methylobacter marinus
BGC0000854.1 |  | 0.61 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.60 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.60 | Other | ectoine | Methylomicrobium kenyense
BGC0000856.1 |  | 0.60 | Other | ectoine | Methylophaga thalassica
BGC0000853.1 |  | 0.60 | Other | ectoine | Streptomyces anulatus
BGC0000852.1 |  | 0.59 | Other | ectoine | Sporosarcina pasteurii
BGC0001526.1 |  | 0.48 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP020398.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 1,628,214 - 1,649,269 nt. (total: 21,056 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.36 | Terpene | carotenoid | Myxococcus xanthus
BGC0001077.1 |  | 0.24 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431
BGC0001928.1 |  | 0.19 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000252.1 |  | 0.18 | Polyketide | nonactin | Streptomyces griseus subsp. griseus
BGC0001120.1 |  | 0.16 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001985.1 |  | 0.14 | Other | pyrazomycin | Streptomyces candidus
BGC0001625.1 |  | 0.14 | Polyketide | isofuranonaphthoquinone | Streptomyces sp. CB01883
BGC0001605.1 |  | 0.14 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001314.1 |  | 0.13 | Terpene | tirucalla | Arabidopsis thaliana
BGC0001190.1 |  | 0.13 | Polyketide | fusaric acid | Fusarium verticillioides 7600

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.69 | Terpene | carotenoid | Myxococcus xanthus
BGC0001077.1 |  | 0.57 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431
BGC0001928.1 |  | 0.51 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000252.1 |  | 0.49 | Polyketide | nonactin | Streptomyces griseus subsp. griseus
BGC0001120.1 |  | 0.46 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001985.1 |  | 0.43 | Other | pyrazomycin | Streptomyces candidus
BGC0001625.1 |  | 0.43 | Polyketide | isofuranonaphthoquinone | Streptomyces sp. CB01883
BGC0001605.1 |  | 0.42 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001314.1 |  | 0.41 | Terpene | tirucalla | Arabidopsis thaliana
BGC0001190.1 |  | 0.41 | Polyketide | fusaric acid | Fusarium verticillioides 7600

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP020398.1 - Region 6 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 1,708,180 - 1,753,058 nt. (total: 44,879 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.28 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.27 | Other | APE Ec | Escherichia coli CFT073
BGC0001075.1 |  | 0.25 | Terpene, Polyketide | aurachin RE | Rhodococcus erythropolis
BGC0000231.1 |  | 0.24 | Polyketide | griseusin | Streptomyces griseus
BGC0001596.1 |  | 0.24 | Polyketide | fluostatins M-Q | Streptomyces albus
BGC0001904.1 |  | 0.24 | Polyketide | fluostatin | Micromonospora rosaria
BGC0000891.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000890.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0001465.1 |  | 0.22 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0001343.1 |  | 0.22 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.61 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.60 | Other | APE Ec | Escherichia coli CFT073
BGC0001075.1 |  | 0.59 | Terpene, Polyketide | aurachin RE | Rhodococcus erythropolis
BGC0000231.1 |  | 0.58 | Polyketide | griseusin | Streptomyces griseus
BGC0001596.1 |  | 0.57 | Polyketide | fluostatins M-Q | Streptomyces albus
BGC0001904.1 |  | 0.57 | Polyketide | fluostatin | Micromonospora rosaria
BGC0000891.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000890.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0001465.1 |  | 0.55 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0001343.1 |  | 0.55 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP020398.1 - Region 7 - phosphonate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 1,786,696 - 1,828,384 nt. (total: 41,689 nt) Show pHMM detection rules used
phosphonate: phosphonates

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | phosphonate | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000904.1 |  | 0.23 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001859.1 |  | 0.23 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0001475.1 |  | 0.17 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0001739.1 |  | 0.16 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0002036.1 |  | 0.16 | Other | dehydrofosmidomycin | Streptomyces lavendulae
BGC0000937.1 |  | 0.15 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001928.1 |  | 0.15 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000897.1 |  | 0.14 | Other | dehydrophos | Streptomyces luridus
BGC0001411.1 |  | 0.12 | Saccharide | polysaccharide B | Bacteroides fragilis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000904.1 |  | 0.57 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001859.1 |  | 0.56 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0001475.1 |  | 0.48 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0001739.1 |  | 0.47 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0002036.1 |  | 0.46 | Other | dehydrofosmidomycin | Streptomyces lavendulae
BGC0000937.1 |  | 0.45 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001928.1 |  | 0.44 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000703.1 |  | 0.43 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000897.1 |  | 0.43 | Other | dehydrophos | Streptomyces luridus
BGC0001411.1 |  | 0.40 | Saccharide | polysaccharide B | Bacteroides fragilis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP020399.1 - Region 1 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 137,489 - 159,624 nt. (total: 22,136 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001201.1 |  | 0.22 | Terpene | eremophilene | Sorangium cellulosum So ce56
BGC0001645.1 |  | 0.21 | RiPP | lagmysin | Streptomyces sp. NRRL S-118
BGC0001634.1 |  | 0.20 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0001496.1 |  | 0.20 | RiPP | actinokineosin | Actinokineospora spheciospongiae
BGC0001655.1 |  | 0.20 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0001551.1 |  | 0.20 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0001550.1 |  | 0.20 | RiPP | citrulassin D | Streptomyces katrae
BGC0001176.1 |  | 0.19 | RiPP | streptomonomicin | Streptomonospora alba
BGC0001549.1 |  | 0.19 | RiPP | citrulassin B | Streptomyces aurantiacus JA 4570
BGC0001356.1 |  | 0.18 | RiPP | paeninodin | Paenibacillus dendritiformis C454

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001201.1 |  | 0.55 | Terpene | eremophilene | Sorangium cellulosum So ce56
BGC0001645.1 |  | 0.54 | RiPP | lagmysin | Streptomyces sp. NRRL S-118
BGC0001634.1 |  | 0.52 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0001496.1 |  | 0.52 | RiPP | actinokineosin | Actinokineospora spheciospongiae
BGC0001655.1 |  | 0.52 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0001551.1 |  | 0.52 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0001550.1 |  | 0.52 | RiPP | citrulassin D | Streptomyces katrae
BGC0001176.1 |  | 0.52 | RiPP | streptomonomicin | Streptomonospora alba
BGC0001549.1 |  | 0.51 | RiPP | citrulassin B | Streptomyces aurantiacus JA 4570
BGC0001356.1 |  | 0.50 | RiPP | paeninodin | Paenibacillus dendritiformis C454

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
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NZ_CP020399.1 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
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Location: 354,716 - 365,531 nt. (total: 10,816 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001882.1 |  | 0.18 | Polyketide | chrysoxanthone A, chrysoxanthone B, chrysoxanthone C | Penicillium rubens Wisconsin 54-1255
BGC0001521.1 |  | 0.18 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0001122.1 |  | 0.04 | NRP, Polyketide | dihydroisoflavipucine, isoflavipucine | Aspergillus terreus NIH2624
BGC0001591.1 |  | 0.03 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.03 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001281.1 |  | 0.03 | Polyketide | ustilagic acid | Ustilago maydis 521
BGC0000700.1 |  | 0.03 | Saccharide | istamycin | Streptomyces tenjimariensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001882.1 |  | 0.50 | Polyketide | chrysoxanthone A, chrysoxanthone B, chrysoxanthone C | Penicillium rubens Wisconsin 54-1255
BGC0001521.1 |  | 0.49 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0001122.1 |  | 0.20 | NRP, Polyketide | dihydroisoflavipucine, isoflavipucine | Aspergillus terreus NIH2624
BGC0001591.1 |  | 0.16 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.16 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001281.1 |  | 0.16 | Polyketide | ustilagic acid | Ustilago maydis 521
BGC0000700.1 |  | 0.16 | Saccharide | istamycin | Streptomyces tenjimariensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

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Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
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