GCF_020554845.1_ASM2055484v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00001_NZ_JAJC.. (original name was: NZ_JAJCIA010000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	betalactone	156,832	189,571

c00006_NZ_JAJC.. (original name was: NZ_JAJCIA010000014.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	ranthipeptide	25,999	47,593

c00027_NZ_JAJC.. (original name was: NZ_JAJCIA010000033.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 27.1	NRPS	6,946	46,084	dipeptide aldehydes	NRP	23%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	betalactone	156,832	189,571
Region 6.1	ranthipeptide	25,999	47,593
Region 27.1	NRPS	6,946	46,084	dipeptide aldehydes	NRP	23%

No secondary metabolite regions were found in these records:: c00002_NZ_JAJC.. (original name was: NZ_JAJCIA010000010.1); c00003_NZ_JAJC.. (original name was: NZ_JAJCIA010000011.1); c00004_NZ_JAJC.. (original name was: NZ_JAJCIA010000012.1); c00005_NZ_JAJC.. (original name was: NZ_JAJCIA010000013.1); c00007_NZ_JAJC.. (original name was: NZ_JAJCIA010000015.1); c00008_NZ_JAJC.. (original name was: NZ_JAJCIA010000016.1); c00009_NZ_JAJC.. (original name was: NZ_JAJCIA010000017.1); c00010_NZ_JAJC.. (original name was: NZ_JAJCIA010000018.1); c00011_NZ_JAJC.. (original name was: NZ_JAJCIA010000019.1); c00012_NZ_JAJC.. (original name was: NZ_JAJCIA010000002.1); c00013_NZ_JAJC.. (original name was: NZ_JAJCIA010000020.1); c00014_NZ_JAJC.. (original name was: NZ_JAJCIA010000021.1); c00015_NZ_JAJC.. (original name was: NZ_JAJCIA010000022.1); c00016_NZ_JAJC.. (original name was: NZ_JAJCIA010000023.1); c00017_NZ_JAJC.. (original name was: NZ_JAJCIA010000024.1); c00018_NZ_JAJC.. (original name was: NZ_JAJCIA010000025.1); c00019_NZ_JAJC.. (original name was: NZ_JAJCIA010000026.1); c00020_NZ_JAJC.. (original name was: NZ_JAJCIA010000027.1); c00021_NZ_JAJC.. (original name was: NZ_JAJCIA010000028.1); c00022_NZ_JAJC.. (original name was: NZ_JAJCIA010000029.1); c00023_NZ_JAJC.. (original name was: NZ_JAJCIA010000003.1); c00024_NZ_JAJC.. (original name was: NZ_JAJCIA010000030.1); c00025_NZ_JAJC.. (original name was: NZ_JAJCIA010000031.1); c00026_NZ_JAJC.. (original name was: NZ_JAJCIA010000032.1); c00028_NZ_JAJC.. (original name was: NZ_JAJCIA010000034.1); c00029_NZ_JAJC.. (original name was: NZ_JAJCIA010000035.1); c00030_NZ_JAJC.. (original name was: NZ_JAJCIA010000036.1); c00031_NZ_JAJC.. (original name was: NZ_JAJCIA010000037.1); c00032_NZ_JAJC.. (original name was: NZ_JAJCIA010000038.1); c00033_NZ_JAJC.. (original name was: NZ_JAJCIA010000039.1); c00034_NZ_JAJC.. (original name was: NZ_JAJCIA010000004.1); c00035_NZ_JAJC.. (original name was: NZ_JAJCIA010000040.1); c00036_NZ_JAJC.. (original name was: NZ_JAJCIA010000041.1); c00037_NZ_JAJC.. (original name was: NZ_JAJCIA010000042.1); c00038_NZ_JAJC.. (original name was: NZ_JAJCIA010000043.1); c00039_NZ_JAJC.. (original name was: NZ_JAJCIA010000044.1); c00040_NZ_JAJC.. (original name was: NZ_JAJCIA010000045.1); c00041_NZ_JAJC.. (original name was: NZ_JAJCIA010000046.1); c00042_NZ_JAJC.. (original name was: NZ_JAJCIA010000047.1); c00043_NZ_JAJC.. (original name was: NZ_JAJCIA010000048.1); c00044_NZ_JAJC.. (original name was: NZ_JAJCIA010000049.1); c00045_NZ_JAJC.. (original name was: NZ_JAJCIA010000005.1); c00046_NZ_JAJC.. (original name was: NZ_JAJCIA010000050.1); c00047_NZ_JAJC.. (original name was: NZ_JAJCIA010000051.1); c00048_NZ_JAJC.. (original name was: NZ_JAJCIA010000052.1); c00049_NZ_JAJC.. (original name was: NZ_JAJCIA010000053.1); c00050_NZ_JAJC.. (original name was: NZ_JAJCIA010000054.1); c00051_NZ_JAJC.. (original name was: NZ_JAJCIA010000055.1); c00052_NZ_JAJC.. (original name was: NZ_JAJCIA010000056.1); c00053_NZ_JAJC.. (original name was: NZ_JAJCIA010000057.1); c00054_NZ_JAJC.. (original name was: NZ_JAJCIA010000058.1); c00055_NZ_JAJC.. (original name was: NZ_JAJCIA010000059.1); c00056_NZ_JAJC.. (original name was: NZ_JAJCIA010000006.1); c00057_NZ_JAJC.. (original name was: NZ_JAJCIA010000060.1); c00058_NZ_JAJC.. (original name was: NZ_JAJCIA010000061.1); c00059_NZ_JAJC.. (original name was: NZ_JAJCIA010000062.1); c00060_NZ_JAJC.. (original name was: NZ_JAJCIA010000063.1); c00061_NZ_JAJC.. (original name was: NZ_JAJCIA010000064.1); c00062_NZ_JAJC.. (original name was: NZ_JAJCIA010000065.1); c00063_NZ_JAJC.. (original name was: NZ_JAJCIA010000066.1); c00064_NZ_JAJC.. (original name was: NZ_JAJCIA010000067.1); c00065_NZ_JAJC.. (original name was: NZ_JAJCIA010000068.1); c00066_NZ_JAJC.. (original name was: NZ_JAJCIA010000069.1); c00067_NZ_JAJC.. (original name was: NZ_JAJCIA010000007.1); c00068_NZ_JAJC.. (original name was: NZ_JAJCIA010000070.1); c00069_NZ_JAJC.. (original name was: NZ_JAJCIA010000071.1); c00070_NZ_JAJC.. (original name was: NZ_JAJCIA010000072.1); c00071_NZ_JAJC.. (original name was: NZ_JAJCIA010000073.1); c00072_NZ_JAJC.. (original name was: NZ_JAJCIA010000074.1); c00073_NZ_JAJC.. (original name was: NZ_JAJCIA010000075.1); c00074_NZ_JAJC.. (original name was: NZ_JAJCIA010000076.1); c00075_NZ_JAJC.. (original name was: NZ_JAJCIA010000077.1); c00076_NZ_JAJC.. (original name was: NZ_JAJCIA010000078.1); c00077_NZ_JAJC.. (original name was: NZ_JAJCIA010000079.1); c00078_NZ_JAJC.. (original name was: NZ_JAJCIA010000008.1); c00079_NZ_JAJC.. (original name was: NZ_JAJCIA010000080.1); c00080_NZ_JAJC.. (original name was: NZ_JAJCIA010000081.1); c00081_NZ_JAJC.. (original name was: NZ_JAJCIA010000082.1); c00082_NZ_JAJC.. (original name was: NZ_JAJCIA010000083.1); c00083_NZ_JAJC.. (original name was: NZ_JAJCIA010000084.1); c00084_NZ_JAJC.. (original name was: NZ_JAJCIA010000085.1); c00085_NZ_JAJC.. (original name was: NZ_JAJCIA010000086.1); c00086_NZ_JAJC.. (original name was: NZ_JAJCIA010000087.1); c00087_NZ_JAJC.. (original name was: NZ_JAJCIA010000088.1); c00088_NZ_JAJC.. (original name was: NZ_JAJCIA010000009.1)

Compact view

c00001_NZ_JAJC.. - Region 1 - betalactone

Download region GenBank file

Download region SVG

Location: 156,832 - 189,571 nt. (total: 32,740 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.21	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.20	NRP	indigoidine	Streptomyces chromofuscus
BGC0000504.1	0.19	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000543.1	0.18	RiPP	pep5	Staphylococcus epidermidis
BGC0001407.1	0.18	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001641.1	0.18	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1	0.17	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.17	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1	0.17	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.1	0.17	NRP	xenematide	Xenorhabdus nematophila AN6/1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.53	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.52	NRP	indigoidine	Streptomyces chromofuscus
BGC0000504.1	0.51	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000543.1	0.50	RiPP	pep5	Staphylococcus epidermidis
BGC0001407.1	0.50	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001641.1	0.49	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1	0.49	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.49	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1	0.49	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.1	0.49	NRP	xenematide	Xenorhabdus nematophila AN6/1

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00006_NZ_JAJC.. - Region 1 - ranthipeptide

Download region GenBank file

Download region SVG

Location: 25,999 - 47,593 nt. (total: 21,595 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001387.1	0.17	Other	nucleocidin	Streptomyces calvus
BGC0001120.1	0.13	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000807.1	0.08	Saccharide	phosphonoglycans	Stackebrandtia nassauensis DSM 44728
BGC0001895.1	0.05	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001591.1	0.05	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.05	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001751.1	0.03	NRP, Polyketide	pyxipyrrolone A, pyxipyrrolone B	Pyxidicoccus sp. MCy9557
BGC0000413.1	0.03	NRP	pyoverdin	Pseudomonas protegens Pf-5

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001387.1	0.48	Other	nucleocidin	Streptomyces calvus
BGC0001120.1	0.42	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000807.1	0.32	Saccharide	phosphonoglycans	Stackebrandtia nassauensis DSM 44728
BGC0001895.1	0.23	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001591.1	0.23	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.23	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001751.1	0.16	NRP, Polyketide	pyxipyrrolone A, pyxipyrrolone B	Pyxidicoccus sp. MCy9557
BGC0000413.1	0.15	NRP	pyoverdin	Pseudomonas protegens Pf-5

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00027_NZ_JAJC.. - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 6,946 - 46,084 nt. (total: 39,139 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000410.1	0.29	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001575.1	0.27	NRP	dipeptide aldehydes	Ruminococcus sp. 5_1_39BFAA
BGC0000308.1	0.26	NRP	aureusimine	Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001699.1	0.25	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001686.1	0.21	NRP	N-octanoyl-Met-Phe-H	Clostridium sp. CAG:567
BGC0000949.1	0.21	NRP	A-500359 A, A-500359 B	Streptomyces griseus
BGC0001479.1	0.21	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000334.1	0.21	NRP	cyclosporine	Tolypocladium inflatum NRRL8044
BGC0001615.1	0.21	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001825.1	0.21	NRP	xenematide	Xenorhabdus nematophila AN6/1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000410.1	0.62	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001575.1	0.61	NRP	dipeptide aldehydes	Ruminococcus sp. 5_1_39BFAA
BGC0000308.1	0.59	NRP	aureusimine	Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001699.1	0.58	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001686.1	0.54	NRP	N-octanoyl-Met-Phe-H	Clostridium sp. CAG:567
BGC0000949.1	0.54	NRP	A-500359 A, A-500359 B	Streptomyces griseus
BGC0001479.1	0.54	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000334.1	0.53	NRP	cyclosporine	Tolypocladium inflatum NRRL8044
BGC0001615.1	0.53	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001825.1	0.53	NRP	xenematide	Xenorhabdus nematophila AN6/1

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 6945 - 46084:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg27_28

Search NORINE for peptide: strict or relaxed

AMP-binding (20..419): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLtdgGIsK
Nearest Stachelhaus code:: aeo
Stachelhaus code match:: 60% (weak)

AMP-binding (1033..1421): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAmfsGAIfK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 60% (weak)

AMP-binding (2028..2419): X

NRPSPredictor2: phe, trp, phg, tyr, bht

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAiTTGgVsK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 70% (weak)