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Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
1.8

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP040441.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 307,878 | 318,243 |
Region 2 | lanthipeptide-class-ii | 508,091 | 535,043 | haloduracin β / haloduracin α | RiPP:Lanthipeptide | 100%
Region 3 | T3PKS | 686,265 | 727,362 | 7-deoxypactamycin | Polyketide:Iterative type I + Saccharide:Hybrid/tailoring | 3%
Region 4 | ectoine | 995,854 | 1,006,243 | ectoine | Other | 66%
Region 5 | betalactone | 1,303,691 | 1,332,079 | fengycin | NRP | 46%
Region 6 | arylpolyene | 1,967,991 | 2,010,147 |
Region 7 | siderophore | 2,731,860 | 2,748,517 |
Region 8 | cyclic-lactone-autoinducer | 3,605,154 | 3,625,850 |

NZ_CP040441.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 307,878 - 318,243 nt. (total: 10,366 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000487.1 |  | 0.17 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000554.1 |  | 0.17 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000551.1 |  | 0.16 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0001639.1 |  | 0.15 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000513.1 |  | 0.15 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000519.1 |  | 0.15 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000616.1 |  | 0.15 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000501.1 |  | 0.15 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0001120.1 |  | 0.14 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000916.1 |  | 0.14 | Other | molybdenum cofactor | Staphylococcus carnosus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000487.1 |  | 0.48 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000554.1 |  | 0.48 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000551.1 |  | 0.46 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0001639.1 |  | 0.46 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000513.1 |  | 0.46 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000519.1 |  | 0.46 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000501.1 |  | 0.45 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0001120.1 |  | 0.44 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000916.1 |  | 0.44 | Other | molybdenum cofactor | Staphylococcus carnosus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040441.1 - Region 2 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 508,091 - 535,043 nt. (total: 26,953 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000517.1 |  | 1.00 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000525.1 |  | 0.35 | RiPP | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0000499.1 |  | 0.27 | RiPP | butyrivibriocin OR79 | Butyrivibrio fibrisolvens
BGC0001576.1 |  | 0.26 | RiPP | divamide A | Prochloron didemni
BGC0000554.1 |  | 0.25 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001229.1 |  | 0.24 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0001660.1 |  | 0.24 | RiPP | mathermycin | Marinactinospora thermotolerans
BGC0000563.1 |  | 0.24 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000523.1 |  | 0.24 | RiPP | lactocin S | Lactobacillus sakei
BGC0000501.1 |  | 0.22 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000517.1 |  | 1.00 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000525.1 |  | 0.68 | RiPP | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0000499.1 |  | 0.60 | RiPP | butyrivibriocin OR79 | Butyrivibrio fibrisolvens
BGC0001576.1 |  | 0.59 | RiPP | divamide A | Prochloron didemni
BGC0000554.1 |  | 0.58 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001229.1 |  | 0.58 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0001660.1 |  | 0.58 | RiPP | mathermycin | Marinactinospora thermotolerans
BGC0000563.1 |  | 0.57 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000523.1 |  | 0.57 | RiPP | lactocin S | Lactobacillus sakei
BGC0000501.1 |  | 0.54 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.

#### Lanthipeptide(s) for ctg1_490 - Putative Class II

ctg1_491 leader / core peptide
  MVNSKDLRNPEFRKAQGLQFVDEVNEKELSSLAGS - GDVHAQDhb DhbWPCADhbVGVDhaVALCPDhb DhbKC Dhb DhaQC
ctg1_492 leader / core peptide
  MTNLLKEWKMPLERTHNNSNPAGDIFQELEDQDILAG - VNGACAWYNIDha CRLGNKGAYC DhbLDhbVECMPDha CN

#### Lanthipeptide(s) for ctg1_493 - Putative Class II

ctg1_491 leader / core peptide
  MVNSKDLRNPEFRKAQGLQFVDEVNEKELSSLAGS - GDVHAQDhb DhbWPCADhbVGVDhaVALCPDhb DhbKC Dhb DhaQC
ctg1_492 leader / core peptide
  MTNLLKEWKMPLERTHNNSNPAGDIFQELEDQDILAG - VNGACAWYNIDha CRLGNKGAYC DhbLDhbVECMPDha CN
allorf_0531409_0531498 leader / core peptide
  VSSSTFPSTSFAA - RDhbAC DhaPGFVDhaRQHEQH

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_491 - Class II
  Cleavage pHMM score: 1.00
  RODEO score: 0
  Monoisotopic mass: 2919.4 Da
  Molecular weight: 2921.3 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2939.3 Da N = 1
    2957.4 Da N = 2
    2975.4 Da N = 3
    2993.4 Da N = 4
ctg1_492 - Class II
  Cleavage pHMM score: 0.40
  RODEO score: 0
  Monoisotopic mass: 3368.5 Da
  Molecular weight: 3370.9 Da
  Number of bridges: 4
ctg1_491 - Class II
  Cleavage pHMM score: 1.00
  RODEO score: 0
  Monoisotopic mass: 2919.4 Da
  Molecular weight: 2921.3 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2939.3 Da N = 1
    2957.4 Da N = 2
    2975.4 Da N = 3
    2993.4 Da N = 4
ctg1_492 - Class II
  Cleavage pHMM score: 0.40
  RODEO score: 0
  Monoisotopic mass: 3368.5 Da
  Molecular weight: 3370.9 Da
  Number of bridges: 4
allorf_0531409_0531498 - Class II
  Cleavage pHMM score: -6.20
  RODEO score: 0
  Monoisotopic mass: 1784.9 Da
  Molecular weight: 1785.9 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1803.9 Da N = 1
    1822.0 Da N = 2

NZ_CP040441.1 - Region 3 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 686,265 - 727,362 nt. (total: 41,098 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.35 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1 |  | 0.33 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001962.1 |  | 0.33 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001310.1 |  | 0.26 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0000937.1 |  | 0.22 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001831.1 |  | 0.22 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000494.1 |  | 0.19 | RiPP | uberolysin | Streptococcus uberis
BGC0000772.1 |  | 0.15 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus
BGC0001808.1 |  | 0.14 | Other | toyocamycin | Streptomyces diastatochromogenes

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.68 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1 |  | 0.66 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001962.1 |  | 0.66 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001310.1 |  | 0.59 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0000937.1 |  | 0.55 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001831.1 |  | 0.55 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000494.1 |  | 0.52 | RiPP | uberolysin | Streptococcus uberis
BGC0000772.1 |  | 0.46 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0001783.1 |  | 0.44 | Other | streptonigrin | Streptomyces flocculus
BGC0001808.1 |  | 0.44 | Other | toyocamycin | Streptomyces diastatochromogenes

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040441.1 - Region 4 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 995,854 - 1,006,243 nt. (total: 10,390 nt) Show pHMM detection rules used
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000858.1 |  | 0.42 | Other | ectoine | Methylobacter marinus
BGC0000852.1 |  | 0.41 | Other | ectoine | Sporosarcina pasteurii
BGC0000855.1 |  | 0.41 | Other | ectoine | Methylomicrobium kenyense
BGC0000859.1 |  | 0.33 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000853.1 |  | 0.33 | Other | ectoine | Streptomyces anulatus
BGC0000856.1 |  | 0.33 | Other | ectoine | Methylophaga thalassica
BGC0000854.1 |  | 0.33 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.31 | Other | ectoine | Methylophaga alcalica
BGC0000860.1 |  | 0.29 | Other | ectoine | Methylarcula marina
BGC0000895.1 |  | 0.14 | Other | citrulline | Lactobacillus plantarum subsp. plantarum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000858.1 |  | 0.73 | Other | ectoine | Methylobacter marinus
BGC0000852.1 |  | 0.72 | Other | ectoine | Sporosarcina pasteurii
BGC0000855.1 |  | 0.72 | Other | ectoine | Methylomicrobium kenyense
BGC0000859.1 |  | 0.67 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000853.1 |  | 0.66 | Other | ectoine | Streptomyces anulatus
BGC0000856.1 |  | 0.66 | Other | ectoine | Methylophaga thalassica
BGC0000854.1 |  | 0.66 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.64 | Other | ectoine | Methylophaga alcalica
BGC0000860.1 |  | 0.63 | Other | ectoine | Methylarcula marina
BGC0000895.1 |  | 0.43 | Other | citrulline | Lactobacillus plantarum subsp. plantarum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040441.1 - Region 5 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,303,691 - 1,332,079 nt. (total: 28,389 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001778.1 |  | 0.27 | Other | showdomycin | Streptomyces showdoensis
BGC0000891.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0001465.1 |  | 0.22 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0000890.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000234.1 |  | 0.21 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000649.1 |  | 0.21 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000258.1 |  | 0.20 | Polyketide | prodigiosin | Serratia sp.
BGC0000938.1 |  | 0.19 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000259.1 |  | 0.19 | Polyketide | prodigiosin | Serratia marcescens
BGC0001440.1 |  | 0.19 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001778.1 |  | 0.60 | Other | showdomycin | Streptomyces showdoensis
BGC0000891.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0001465.1 |  | 0.55 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0000890.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000234.1 |  | 0.54 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000649.1 |  | 0.53 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000258.1 |  | 0.52 | Polyketide | prodigiosin | Serratia sp.
BGC0000938.1 |  | 0.51 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000259.1 |  | 0.51 | Polyketide | prodigiosin | Serratia marcescens
BGC0001440.1 |  | 0.50 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040441.1 - Region 6 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,967,991 - 2,010,147 nt. (total: 42,157 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001535.1 |  | 0.22 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0002012.1 |  | 0.22 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0002000.1 |  | 0.22 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001897.1 |  | 0.21 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000839.1 |  | 0.20 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001534.1 |  | 0.19 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0000838.1 |  | 0.19 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000271.1 |  | 0.18 | Polyketide | spore pigment | Streptomyces avermitilis
BGC0001730.1 |  | 0.18 | Polyketide | paramagnetoquinone 1, paramagnetoquinone 2 | Actinoallomurus sp.
BGC0000235.1 |  | 0.18 | Polyketide | kiamycin | Streptomyces sp. W007

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001535.1 |  | 0.55 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0002012.1 |  | 0.55 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0002000.1 |  | 0.55 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001897.1 |  | 0.54 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000839.1 |  | 0.52 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001534.1 |  | 0.51 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0000838.1 |  | 0.50 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000271.1 |  | 0.50 | Polyketide | spore pigment | Streptomyces avermitilis
BGC0001730.1 |  | 0.50 | Polyketide | paramagnetoquinone 1, paramagnetoquinone 2 | Actinoallomurus sp.
BGC0000235.1 |  | 0.49 | Polyketide | kiamycin | Streptomyces sp. W007

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040441.1 - Region 7 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,731,860 - 2,748,517 nt. (total: 16,658 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000942.1 |  | 0.30 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001572.1 |  | 0.27 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001478.1 |  | 0.27 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000853.1 |  | 0.26 | Other | ectoine | Streptomyces anulatus
BGC0000941.1 |  | 0.25 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000855.1 |  | 0.25 | Other | ectoine | Methylomicrobium kenyense
BGC0000859.1 |  | 0.25 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000852.1 |  | 0.25 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  | 0.25 | Other | ectoine | Methylobacter marinus
BGC0000856.1 |  | 0.25 | Other | ectoine | Methylophaga thalassica

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000942.1 |  | 0.63 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001572.1 |  | 0.61 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001478.1 |  | 0.61 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000853.1 |  | 0.59 | Other | ectoine | Streptomyces anulatus
BGC0000941.1 |  | 0.59 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000855.1 |  | 0.59 | Other | ectoine | Methylomicrobium kenyense
BGC0000859.1 |  | 0.59 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000852.1 |  | 0.58 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  | 0.58 | Other | ectoine | Methylobacter marinus
BGC0000856.1 |  | 0.58 | Other | ectoine | Methylophaga thalassica

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040441.1 - Region 8 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,605,154 - 3,625,850 nt. (total: 20,697 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.26 | RiPP | circularin A | Clostridium beijerinckii
BGC0000487.1 |  | 0.17 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000544.1 |  | 0.17 | RiPP | planosporicin | Planomonospora alba
BGC0000554.1 |  | 0.17 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000571.1 |  | 0.16 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000517.1 |  | 0.16 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000552.1 |  | 0.16 | RiPP | SmbA, SmbB | Streptococcus mutans
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000513.1 |  | 0.16 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000519.1 |  | 0.16 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.60 | RiPP | circularin A | Clostridium beijerinckii
BGC0000487.1 |  | 0.48 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000544.1 |  | 0.48 | RiPP | planosporicin | Planomonospora alba
BGC0000554.1 |  | 0.48 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000571.1 |  | 0.47 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000517.1 |  | 0.47 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000552.1 |  | 0.47 | RiPP | SmbA, SmbB | Streptococcus mutans
BGC0001210.1 |  | 0.47 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000513.1 |  | 0.47 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000519.1 |  | 0.47 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names