LOCUS       NC_005090.1            10801 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_005090.1 Wolinella succinogenes DSM 1740, complete sequence.
ACCESSION   NC_005090
VERSION     NC_005090.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:54:54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 279872
            Orig. end    :: 290673
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10801
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[284872:285673](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5801
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10801
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10801
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(638..1792)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 255.9; E-value: 6.2e-78)"
                     /gene_kind="other"
                     /locus_tag="ctg1_266"
                     /transl_table=11
                     /translation="MSRKRKSYSAEFKTRVVLELLGGEETVAQIASKYEITPKSLIDWK
                     KQFLENASLVFDVGSATKAYKDEIEELKTENDALAKKLGKTTIERDWAVGKLKSLGLSN
                     KKDLVTPKLKNLSMARQCEIIDLNRSTLYYEPKPISDNDLKIMKRIDEIYTDISSTYGY
                     RFMHRQLLEDGFSIGVNKVNKLMNTMGIQAIFPKKKRHTSIKNYKHKIYPYLLRELEIN
                     RANQVWSGDITYIPIKGGFVYLCAIIDWHSKTILSWKISTTMDTSLVTDVLKEAIEKYD
                     IPVIFNSDQGSQYTSHEHTELLKKHNIQISMNGKGRSIDNIAIERFFRTLKYDEIYINE
                     YSSISDLRFKVSRYINFYNHNRFHSALNYQKPMNVYLEGLKNVA"
     PFAM_domain     complement(842..1126)
                     /aSDomain="rve"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00665.28"
                     /description="Integrase core domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_266_0003"
                     /evalue="1.70E-25"
                     /label="ctg1_266"
                     /locus_tag="ctg1_266"
                     /protein_end="317"
                     /protein_start="222"
                     /score="89.4"
                     /tool="antismash"
                     /translation="RANQVWSGDITYIPIKGGFVYLCAIIDWHSKTILSWKISTTMDTS
                     LVTDVLKEAIEKYDIPVIFNSDQGSQYTSHEHTELLKKHNIQISMNGKGR"
     PFAM_domain     complement(1196..1369)
                     /aSDomain="HTH_21"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13276.8"
                     /description="HTH-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_266_0002"
                     /evalue="2.20E-11"
                     /label="ctg1_266"
                     /locus_tag="ctg1_266"
                     /protein_end="199"
                     /protein_start="141"
                     /score="43.8"
                     /tool="antismash"
                     /translation="NDLKIMKRIDEIYTDISSTYGYRFMHRQLLEDGFSIGVNKVNKLM
                     NTMGIQAIFPKKK"
     PFAM_domain     complement(1565..1786)
                     /aSDomain="HTH_Tnp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01527.22"
                     /description="Transposase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_266_0001"
                     /evalue="7.40E-11"
                     /label="ctg1_266"
                     /locus_tag="ctg1_266"
                     /protein_end="76"
                     /protein_start="2"
                     /score="42.3"
                     /tool="antismash"
                     /translation="RKRKSYSAEFKTRVVLELLGGEETVAQIASKYEITPKSLIDWKKQ
                     FLENASLVFDVGSATKAYKDEIEELKTEN"
     CDS             1902..2447
                     /locus_tag="ctg1_267"
                     /transl_table=11
                     /translation="MLRESMQNLSQGANEQAASLQESASAIEEMSSSMHNVSDRASEVI
                     KQSEDIKNVITIIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSL
                     GEIEANTNVLVQSINEMSESIKEQAQGISQINEAIAQLDTLTQQNATVADRTDGIAQEV
                     SQTADDLLGIVSKSRFIP"
     PFAM_domain     1998..2405
                     /aSDomain="MCPsignal"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00015.23"
                     /description="Methyl-accepting chemotaxis protein (MCP)
                     signalling domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_267_0004"
                     /evalue="3.40E-36"
                     /label="ctg1_267"
                     /locus_tag="ctg1_267"
                     /protein_end="168"
                     /protein_start="32"
                     /score="124.7"
                     /tool="antismash"
                     /translation="SMHNVSDRASEVIKQSEDIKNVITIIRDIADQTNLLALNAAIEAA
                     RAGEHGRGFAVVADEVRKLAERTQKSLGEIEANTNVLVQSINEMSESIKEQAQGISQIN
                     EAIAQLDTLTQQNATVADRTDGIAQEVSQTAD"
     CDS             2588..4552
                     /locus_tag="ctg1_268"
                     /transl_table=11
                     /translation="MEQYEQFSRFMPAILGYRDQFISLNSQLKKTTLTGKISSLETAEN
                     LFAYMETTQQKFSELQRRLLDALVEQNLHRVSDLLGNTAQVSIDILVRNLFERTADVGF
                     LAMDEDIIDFLLRPDTQAEQRASLEHRLFEYAQKYTVYQEILVLDAELFCVAHLDANNK
                     PISKTSSFGARVLDSKEAFEEFFGVDSLYGEGESALFYGSPIRQEGRVIGALVLVFDFA
                     GEMKRIYNKLQEGSLGVNYALLDERGRIISSLNESLLPVGSNAPCSLSEKLGTITLKNR
                     EYFILCAKSRGYQGYGGPKDWCALSLWRVDELRRLEFRRSVEAKLEEDIEDSPLVGASL
                     ASIINEAQEIYEDLNDVVINGEIIASKTHSYALNAILDRIRAISHHINALCIHSITELL
                     ESIESASHENLRFYSGLAMDILDRNLYERANDCRWWALHTHFRHTLAKESPTAEEIERF
                     GEILCAIHSLYTVYYNLFVFDASGKILASSHPNEQDKIGKFLPRETLKAVLACKNPQEY
                     HLSSFESSPFYREEPTFVYYGAIFPLLGGKPVGGIGIVFDSTPQFHAMLEDSLPRDEKG
                     EAIEGVFGCFVDQAGKIIAKTQGGEVPPLEGVFEAIKGEGRAEKILYPDGGEQLFGIRR
                     SGGYREYKSGLYAAMFRKV"
     CDS             4624..4998
                     /locus_tag="ctg1_269"
                     /transl_table=11
                     /translation="MVHEGAKEAAERLPEEVVDYHRIIQSTIEELEAVDLYNQRAAATK
                     DPAVRAIMEHNRDEEIEHAVMGLEWLRRHSPVWDETMRALLFKEGEIISHEQAFTGKTG
                     EVASALGSNGLNIGSLKKGK"
     aSDomain        4642..4986
                     /aSDomain="TIGR04535"
                     /aSTool="tigrfam"
                     /description="ferrit_encaps: ferritin-like protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_269_0001"
                     /evalue="2.60E-42"
                     /identifier="TIGR04535"
                     /label="ctg1_269"
                     /locus_tag="ctg1_269"
                     /protein_end="121"
                     /protein_start="6"
                     /score="141.4"
                     /tool="antismash"
                     /translation="KEAAERLPEEVVDYHRIIQSTIEELEAVDLYNQRAAATKDPAVRA
                     IMEHNRDEEIEHAVMGLEWLRRHSPVWDETMRALLFKEGEIISHEQAFTGKTGEVASAL
                     GSNGLNIGSLK"
     PFAM_domain     5001..5756
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_270_0005"
                     /evalue="4.00E-76"
                     /label="ctg1_270"
                     /locus_tag="ctg1_270"
                     /protein_end="252"
                     /protein_start="0"
                     /score="255.8"
                     /tool="antismash"
                     /translation="MDILRRENAQFPASIWSAIEKEAGLVFGKHLTGRKVVDFKGGLGI
                     GFSSLPTGRVISSKEKLGEASVGVRMNTPVIELKIPFSFPESEVEAILREANAFDISSI
                     EKAAKKVCVAENELVFYGLKKEGIEGLIPSIPHKPIKAKGDEILPAVAEGIKELVNSEI
                     EGPYALLIQPQYFGKLFGVAGNSGYPLTLKLAELLQGNNIIVAPALKSGALLVSLRGGD
                     YELYSGMDIGVGYSEKKSTNHELFFFETLT"
     CDS             5001..5801
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_270"
                     /sec_met_domain="Linocin_M18 (E-value: 2.5e-70, bitscore:
                     233.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDILRRENAQFPASIWSAIEKEAGLVFGKHLTGRKVVDFKGGLGI
                     GFSSLPTGRVISSKEKLGEASVGVRMNTPVIELKIPFSFPESEVEAILREANAFDISSI
                     EKAAKKVCVAENELVFYGLKKEGIEGLIPSIPHKPIKAKGDEILPAVAEGIKELVNSEI
                     EGPYALLIQPQYFGKLFGVAGNSGYPLTLKLAELLQGNNIIVAPALKSGALLVSLRGGD
                     YELYSGMDIGVGYSEKKSTNHELFFFETLTFRINTPEASIAIEW"
     CDS             5900..6886
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 60.9; E-value: 1.9e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_271"
                     /transl_table=11
                     /translation="MKPPIKIDYRASIDITKKITHPFSREVYMGKMKEELGEGSGIWYD
                     MGHGIALAVREFVPRQEMVIFEQSDVAGAVFIFNLGSDLRFVFKDQKEHLLKKNRFLVG
                     LASTQFYVETPFSSGQVWSTLTTAMKQELFLELATPIKNIQEHLKEASKHSYSIFQDRS
                     IDPKQLELLRYLQKRDSYEETLESIHLESKATELIHYTIERMARALDDSSLSALEEGWL
                     SSLERAREIILQDYHNPHLSIKEIAYRSAINECYLKRDFKKHYGMTILEMIQKRRLEVA
                     KELLHERLTLKEVAQEVGYRHVGHFSKLFSERFGITPSDYKKELRNF"
     PFAM_domain     6638..6868
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_271_0006"
                     /evalue="6.30E-21"
                     /label="ctg1_271"
                     /locus_tag="ctg1_271"
                     /protein_end="323"
                     /protein_start="246"
                     /score="74.5"
                     /tool="antismash"
                     /translation="AYRSAINECYLKRDFKKHYGMTILEMIQKRRLEVAKELLHERLTL
                     KEVAQEVGYRHVGHFSKLFSERFGITPSDYKK"
     CDS             6993..9059
                     /gene_functions="transport (smcogs)
                     SMCOG1051:TonB-dependent siderophore receptor (Score:
                     546.3; E-value: 1.9e-165)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_272"
                     /transl_table=11
                     /translation="MEKGKWFSKLSPSLCALLLAGGVSALAQEEADKLNNVLISEEIPT
                     NYASKEKSAIMRSNIKPDESAKSVQIFNETYMQDTQAQTINDVIKMSSNTTYLGDNNGR
                     ESLFAIRGFSGVPILRDGLSLTNAAPFPEVFNLESIEVLKGPDSLQYGQSSPGGIVNLV
                     VKKPLYETYAQIELETTSNTSYSPKVDLGGALNDSKTLRYRLVALARHDEGFRDSHVNS
                     DRVFIAPTLAYDISDDHTFTLVSEYLDERTPSSFESYVNSKGELVADIKTIMSHPDEKF
                     DKTQKIIGFDLDSRFGTWKSNLKYRYVDYLRDNYNVHIPYAYVEATNQVRRFFATQKYD
                     FTEHALQYTLNKELEIFNLKNKITMGADFGRASTTFTGWMDMGTIYALNLSNLKYEALT
                     DLSDHPSAVTYGNTGEKITTTKKGIFAQDNLYLSENLILSTGVRYSTVKSDTSDKSSAW
                     TPQIGLVYKLTPETSLYANYSESFTPQSATDINGKILDPEEGEGVELGIKQKLFGDRLA
                     LTAAVFKIEKVNVAMPDPINPLKSVASGKQESKGFEFDVSGDITSDWSMAASYGYTSTE
                     DKATNQGKELSGIPKHTANLFTTHYLTAFGLPHFYVGGGVRYLGERYANSTNTIKLDSS
                     LIYSAMVGYRKGNWRGALSVQNITDEVYVESASNSRVSVGTPRTVVATLGYLF"
     PFAM_domain     7179..7469
                     /aSDomain="Plug"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07715.17"
                     /description="TonB-dependent Receptor Plug Domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_272_0007"
                     /evalue="1.50E-14"
                     /label="ctg1_272"
                     /locus_tag="ctg1_272"
                     /protein_end="159"
                     /protein_start="62"
                     /score="54.6"
                     /tool="antismash"
                     /translation="DESAKSVQIFNETYMQDTQAQTINDVIKMSSNTTYLGDNNGRESL
                     FAIRGFSGVPILRDGLSLTNAAPFPEVFNLESIEVLKGPDSLQYGQSSPGGI"
     aSDomain        7185..9056
                     /aSDomain="TIGR01783"
                     /aSTool="tigrfam"
                     /description="TonB-siderophor: TonB-dependent siderophore
                     receptor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_272_0002"
                     /evalue="2.60E-91"
                     /identifier="TIGR01783"
                     /label="ctg1_272"
                     /locus_tag="ctg1_272"
                     /protein_end="688"
                     /protein_start="64"
                     /score="305.2"
                     /tool="antismash"
                     /translation="SAKSVQIFNETYMQDTQAQTINDVIKMSSNTTYLGDNNGRESLFA
                     IRGFSGVPILRDGLSLTNAAPFPEVFNLESIEVLKGPDSLQYGQSSPGGIVNLVVKKPL
                     YETYAQIELETTSNTSYSPKVDLGGALNDSKTLRYRLVALARHDEGFRDSHVNSDRVFI
                     APTLAYDISDDHTFTLVSEYLDERTPSSFESYVNSKGELVADIKTIMSHPDEKFDKTQK
                     IIGFDLDSRFGTWKSNLKYRYVDYLRDNYNVHIPYAYVEATNQVRRFFATQKYDFTEHA
                     LQYTLNKELEIFNLKNKITMGADFGRASTTFTGWMDMGTIYALNLSNLKYEALTDLSDH
                     PSAVTYGNTGEKITTTKKGIFAQDNLYLSENLILSTGVRYSTVKSDTSDKSSAWTPQIG
                     LVYKLTPETSLYANYSESFTPQSATDINGKILDPEEGEGVELGIKQKLFGDRLALTAAV
                     FKIEKVNVAMPDPINPLKSVASGKQESKGFEFDVSGDITSDWSMAASYGYTSTEDKATN
                     QGKELSGIPKHTANLFTTHYLTAFGLPHFYVGGGVRYLGERYANSTNTIKLDSSLIYSA
                     MVGYRKGNWRGALSVQNITDEVYVESASNSRVSVGTPRTVVATLGYLF"
     PFAM_domain     7695..9050
                     /aSDomain="TonB_dep_Rec"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00593.26"
                     /description="TonB dependent receptor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_272_0008"
                     /evalue="3.60E-57"
                     /label="ctg1_272"
                     /locus_tag="ctg1_272"
                     /protein_end="686"
                     /protein_start="234"
                     /score="195.4"
                     /tool="antismash"
                     /translation="ISDDHTFTLVSEYLDERTPSSFESYVNSKGELVADIKTIMSHPDE
                     KFDKTQKIIGFDLDSRFGTWKSNLKYRYVDYLRDNYNVHIPYAYVEATNQVRRFFATQK
                     YDFTEHALQYTLNKELEIFNLKNKITMGADFGRASTTFTGWMDMGTIYALNLSNLKYEA
                     LTDLSDHPSAVTYGNTGEKITTTKKGIFAQDNLYLSENLILSTGVRYSTVKSDTSDKSS
                     AWTPQIGLVYKLTPETSLYANYSESFTPQSATDINGKILDPEEGEGVELGIKQKLFGDR
                     LALTAAVFKIEKVNVAMPDPINPLKSVASGKQESKGFEFDVSGDITSDWSMAASYGYTS
                     TEDKATNQGKELSGIPKHTANLFTTHYLTAFGLPHFYVGGGVRYLGERYANSTNTIKLD
                     SSLIYSAMVGYRKGNWRGALSVQNITDEVYVESASNSRVSVGTPRTVVATLGY"
     CDS             9428..10228
                     /locus_tag="ctg1_273"
                     /transl_table=11
                     /translation="MSRFFSKITSVVLLSLLLVLGVQAATIEVISSGAFYATMEELKPL
                     FEKKTGHEVHLQSGSSMGASETSIPNRLKRGETFDLIILASGQLEKMIADGYATKGSRV
                     DLVHSSIGMMVRKGEPKPDISTQAAFDKALKDAKSIGYSASASGTHLAEKVFPGFGESV
                     TSKTKLIVGDRVATWVGRGDLEIGFQQVSEITPFTGEKGSVDLVGPIPAPYQKVTIFSV
                     GVANGSKEPQAARELVEFLTSKENYSRLMEQGLVPAAMAVETAK"
     PFAM_domain     9509..10189
                     /aSDomain="SBP_bac_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13531.8"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_273_0009"
                     /evalue="1.10E-27"
                     /label="ctg1_273"
                     /locus_tag="ctg1_273"
                     /protein_end="254"
                     /protein_start="27"
                     /score="97.4"
                     /tool="antismash"
                     /translation="EVISSGAFYATMEELKPLFEKKTGHEVHLQSGSSMGASETSIPNR
                     LKRGETFDLIILASGQLEKMIADGYATKGSRVDLVHSSIGMMVRKGEPKPDISTQAAFD
                     KALKDAKSIGYSASASGTHLAEKVFPGFGESVTSKTKLIVGDRVATWVGRGDLEIGFQQ
                     VSEITPFTGEKGSVDLVGPIPAPYQKVTIFSVGVANGSKEPQAARELVEFLTSKENYSR
                     LMEQG"
ORIGIN
        1 actcaaagac caactcaaaa gctttgccct ccttggagcg atatttgtgg tagtggggtt
       61 ggtctcgctc tatcttctgc tcaccaagat gcttaagccc attgagacca ttaaagattc
      121 tttggtaggg ttttttgcct tccttaatca tgaacgaagc agtgtggagc cgatttcgct
      181 gaagcagaat gacgaatttg gggtgatggc ttcgcttatt aatgagaata ttgagaggat
      241 cacccaaagt gttatccagg atcgagaatc ggtagcagaa gcgctcaaaa ccgtggagcg
      301 aatcaaagag ggctatcttg atagagatat tgtctctagc cctgccaacc ctcaactcga
      361 agagctcaaa aaagtgctca atgagatggt ggtggtgcta aggcaaaaag taggcaaaga
      421 tatcaatcgc ctcaacagcg tgatgcagac cttctctaag gtcgatttca cctccaagat
      481 cgagggggcg agctctgatt ttgagcgtgc gctcaaccat atcggcgagg aggtctcggc
      541 agtgcttcga gagaacaccc atgtggctaa tactatactg ccaccatttg tcaagacaac
      601 tttttgagaa ttcatcttcc agcctctagc ctttaattta agcaacgttt ttcaaccctt
      661 ctagataaac attcatgggc ttttgataat ttagtgctga atgaaatcta ttgtgattgt
      721 aaaaattgat atatcttgaa accttaaatc tgagatctga aatagagcta tactcattga
      781 tatagatttc atcatatttt aaagtcctaa aaaatctctc aatggcaata ttatcaatgg
      841 atctgccttt accgttcata gagatttgaa tgttgtgttt cttgagaagt tctgtatgtt
      901 catggctggt atattggcta ccttggtcgg agttgaatat tacaggaatg tcatattttt
      961 caatggcttc ttttaaaaca tctgttacaa gagatgtatc catagttgtt gatattttcc
     1021 atgagagtat cgttttactg tgccaatcaa taatggcgca caaatacacg aaaccaccct
     1081 tgattgggat ataggtaata tctccactcc aaacctgatt ggctctgtta atttcaagct
     1141 ctcgtagtag atatggatag attttatgtt tatagttttt aatggatgtg tgtcgtttct
     1201 tttttggaaa gattgcctgt atccccatag tgttcattag cttattgact ttatttacac
     1261 caattgaaaa tccatcttcc aaaagctgcc tatgcataaa ccgatagcca taggttgagg
     1321 atatatcagt atatatctca tctatccttt tcatgatttt taaatcattg tctgatatgg
     1381 gtttaggttc ataataaagg gttgagcgat ttaaatctat tatttcacat tgtcttgcca
     1441 tggagagatt ctttagcttg ggtgtgacaa gatctttttt atttgataag cccaagctct
     1501 ttagctttcc cactgcccaa tccctctcta tggttgtttt tcctaatttc tttgctagag
     1561 catcattctc tgtttttagc tcttctatct catctttata ggctttagta gccgaaccta
     1621 catcaaatac tagtgatgca ttctctaaaa actgcttttt ccaatcaatg agactttttg
     1681 gtgtaatctc atatttactg gcaatctgtg ctacagtctc ttcgccacct agtaattcta
     1741 agacaactct agttttaaat tctgcactat agctttttct ttttctactc attttttcct
     1801 ctcctaaatc tttagaaaat tctaccattt aggaagataa acctttcaat ttattgtctt
     1861 gaattttagt ggcagtatat accttggaag agaaggcaaa gatgctaagg gaatcgatgc
     1921 aaaatctttc ccaaggagcc aatgagcaag ccgccagcct ccaagagagc gcttcggcaa
     1981 tcgaggagat gagtagctct atgcacaatg tgagcgatcg cgcctctgaa gtgatcaaac
     2041 aatctgaaga tattaagaat gtcatcacta tcatccgcga tatcgctgac cagacgaatc
     2101 ttcttgcgct caatgccgcg attgaggccg ctagagcggg agagcatgga agaggatttg
     2161 ctgtggtggc tgatgaggtg agaaagctcg ctgagcgcac ccaaaagagc cttggtgaaa
     2221 ttgaggccaa cactaatgtt ttggtgcaat ccatcaatga gatgagcgaa agcatcaaag
     2281 aacaagctca gggaatctcc caaatcaacg aggcaatcgc ccagctagat acgctcaccc
     2341 aacaaaatgc caccgtggcc gatcgaaccg atggaattgc ccaggaggtg agccagactg
     2401 ccgatgatct cctgggaatc gtctccaaaa gccgcttcat tccctaaatc tttcctctcc
     2461 aagccttcgg gcttggactg cctctttttt aatcaaatcg tttagccttt ttgtcgctta
     2521 aactttgtat agttgccttg ccattttgaa tctcttcccg ccctctacac agataaaagg
     2581 ggtgaaaatg gaacaatacg agcagttttc tcgcttcatg ccagcgattc ttggctatcg
     2641 agatcagttt atctctctca attcccaact caaaaaaacc acccttactg gcaagatcag
     2701 ctcgctagag acagcggaaa atctcttcgc ctatatggag acaactcaac agaaattctc
     2761 cgagctccaa agacggcttt tggatgcttt agtggagcaa aatcttcatc gagtctccga
     2821 tctcttggga aacacagctc aggtgagtat tgacattctt gtgcgaaatc ttttcgagcg
     2881 gactgcggat gtggggtttt tggcgatgga tgaggatatc atcgatttcc tgttgcgccc
     2941 tgatacacaa gcagagcagc gtgcgagttt ggagcaccga ctctttgaat atgcgcaaaa
     3001 gtacaccgtc tatcaagaga ttcttgtttt ggacgcggag ctattttgtg tagcgcatct
     3061 agacgcaaat aataaaccca tctccaaaac ctcttctttt ggggctaggg tgcttgattc
     3121 taaagaggcg tttgaggagt tttttggagt cgattctctt tatggtgaag gagaatcagc
     3181 tcttttttat ggctctccta ttcgccaaga agggagagtg atcggtgcgc tggtgttggt
     3241 gtttgatttt gcgggggaga tgaaacgaat ctataacaaa ctgcaagagg gctctttggg
     3301 ggtgaactac gctcttttgg atgagagggg tcgtatcatc tcttcgctca acgaatcgct
     3361 actgcctgtg ggatcaaatg ctccttgctc tttgagcgaa aagttaggga ctatcacgct
     3421 caaaaacagg gaatatttca ttctctgtgc caaaagccga ggataccaag ggtatggagg
     3481 gccaaaggat tggtgtgcgc tgagtctttg gagggtggat gagctacgcc gtttagagtt
     3541 tcgtcgaagt gtggaggcga aacttgagga agatattgag gattctcctt tggtgggggc
     3601 ttcgctcgcc tctattatta acgaggcgca agagatttat gaggatttga atgatgtggt
     3661 gatcaacgga gagattatcg cttccaaaac ccacagctac gcgcttaatg cgattcttga
     3721 tcgaatcagg gcgattagtc accacattaa cgcgctatgc attcactcca tcaccgaatt
     3781 gcttgaatcc atcgagagtg cttcgcacga aaatctccga ttctactcag gcttggcgat
     3841 ggatattttg gatcgcaatc tctatgagcg cgctaatgat tgccgatggt gggctctgca
     3901 tacgcacttt cgtcacacgc tcgccaagga atcgcccaca gcagaggaga ttgagcgttt
     3961 tggtgaaata ttgtgcgcaa ttcactcact ctatacggtc tactacaatc tttttgtttt
     4021 tgacgcctca ggcaagattc tcgcctcttc acatccaaat gagcaggaca agatcggcaa
     4081 attcctccct cgtgagacgc tcaaggcggt gctggcttgt aaaaatcccc aagagtatca
     4141 tctctcctct tttgagtctt cgccttttta tagagaagag ccgacctttg tctattatgg
     4201 agcgatcttt cctctcttag gaggcaagcc tgtaggggga attggaatcg tctttgattc
     4261 tacgccgcag tttcacgcga tgcttgaaga ttcgctccct agagacgaga agggagaggc
     4321 aatagaggga gtgtttgggt gctttgtgga tcaagcaggc aaaattattg ccaagacgca
     4381 agggggcgag gttcctcctt tggagggggt gtttgaggcg atcaagggag aggggcgggc
     4441 tgagaagatt ctttaccctg atgggggtga gcagttattt ggaatcaggc gttctggcgg
     4501 ctatcgagag tataaaagcg ggctttatgc ggcgatgttt aggaaggtct agtttgcctt
     4561 ggtatttgag ggaatttgtg ctacgcttta tgaatggata gtttaagaac aaaggagaga
     4621 tagatggtac acgaaggagc caaagaggca gcagagagac tcccagaaga ggtggtggat
     4681 taccatcgaa ttatccaaag cacgattgag gagctagagg cggttgatct ctataatcag
     4741 cgagctgcgg cgaccaaaga tcctgcggtt cgagcgatca tggagcacaa tcgcgatgaa
     4801 gagattgagc acgctgtcat ggggctagag tggcttaggc gtcacagccc tgtatgggat
     4861 gagacgatgc gagccctgct tttcaaagag ggagagatta tcagtcacga acaggccttc
     4921 acgggcaaga cgggcgaggt agcctcagct ttgggatcaa atgggctcaa tattggaagt
     4981 ttaaagaaag gaaaatagtc atggatattc tacgaagaga aaacgcacaa ttccccgcct
     5041 ccatctggag cgctatcgaa aaagaggcag gtttggtttt tggcaagcac ctcacgggtc
     5101 gtaaagtggt cgatttcaaa ggggggttgg gaatcggctt tagctccttg cccacgggtc
     5161 gagtgatctc ctccaaggag aaattaggcg aggcgagtgt gggagtgaga atgaacacac
     5221 ctgtgattga gctaaagatt cctttctcct tccctgagag cgaagtggag gcgattttgc
     5281 gagaggcaaa cgcttttgac atctccagca ttgaaaaggc cgccaagaag gtgtgtgtcg
     5341 ctgagaatga actggtcttt tacggtctta aaaaagaggg catcgaaggt ctcatcccct
     5401 ccatccccca taagcccatc aaagccaagg gcgatgagat actccccgcg gtggctgagg
     5461 gaatcaagga gcttgtcaac tccgagattg aaggtcccta tgcacttctt attcagccgc
     5521 aatattttgg caagctcttt ggggtggcgg gcaactctgg ctatcctctc acgctcaagc
     5581 tcgctgagct tcttcagggc aacaatatta tcgtcgctcc cgcactcaag agcggagcgc
     5641 ttcttgtgag ccttcgaggg ggagattatg agctctacag cgggatggat attggcgtgg
     5701 gctatagcga gaaaaaatca accaaccacg agctattctt ctttgagacg ctcaccttcc
     5761 gtatcaacac ccccgaagcg tctatcgcga tcgagtggta aaccgtcctc ttccttgatt
     5821 cttctcctga ggatttttga gaatccttgg ggggggaatc ggactctttt ctaacctctc
     5881 ttaatgtaga atcattctca tgaaaccacc catcaaaata gactatcgcg cctctatcga
     5941 catcaccaag aagatcactc accccttctc acgagaggtc tatatgggca aaatgaaaga
     6001 ggagttgggt gagggatcgg ggatatggta tgacatgggg catggtatcg ctttggcggt
     6061 gagggagttt gtcccgcgcc aagagatggt gatttttgag cagagcgatg tggcgggtgc
     6121 ggtttttatc tttaacctag gctcggattt gcgctttgtt tttaaggatc aaaaggagca
     6181 tctcctcaaa aagaatcgat tcttggtggg gctagcctcg actcaatttt atgtagagac
     6241 tccattctca tcggggcagg tttggtctac gctcaccact gcgatgaagc aagagctttt
     6301 tttggagctc gctacaccaa tcaaaaatat ccaagagcat ctcaaagagg cctccaagca
     6361 tagttactcc atttttcagg atcgaagcat tgaccccaag cagcttgaac tgttgcgcta
     6421 tctccaaaag agagattctt atgaagagac ccttgagagc atccacctcg aatcaaaagc
     6481 cactgagctc atccactaca ccatcgagcg aatggcaagg gcgcttgatg attcttcatt
     6541 gagtgctttg gaggaggggt ggctctcctc tttggagcga gcaagagaga ttatcctcca
     6601 agactatcac aaccctcatc tctccatcaa agagatcgcc tatcgctcag cgatcaatga
     6661 gtgctacctc aagagagact tcaaaaagca ctacggaatg accattttag agatgattca
     6721 aaagcgtcgc ttggaggttg ctaaggagtt gcttcatgag cgcctcacgc tcaaagaggt
     6781 tgcccaagag gtcggatata ggcatgtggg gcacttcagc aaactcttct ccgagcgctt
     6841 tggaatcacc ccaagtgact ataaaaaaga gctccgaaat ttctagaatt tttcccatta
     6901 gcgcacaaat cttttccttt tggtgactct attaatattg ataatggaaa tcataaatga
     6961 taacatcgcc aaaactttta tggaggatgt ctatggaaaa aggaaaatgg ttctctaagc
     7021 tctctccctc tctctgcgcg ctgcttcttg ctggtggggt gtcagcgctc gctcaagagg
     7081 aggcggataa gctcaacaat gttctaatct cagaagagat tccgaccaac tacgcgagca
     7141 aagagaagtc tgcaattatg agaagcaata tcaagcctga tgagagcgcg aagtcggttc
     7201 agattttcaa cgagacctat atgcaggata ctcaagcgca gaccatcaac gatgtgatca
     7261 aaatgtcctc gaatacaacc tatttgggag ataacaacgg cagagagagc ctctttgcga
     7321 tccgaggctt ttcaggagtc cctatcttgc gcgatggatt gagtctcacc aatgctgcgc
     7381 cctttcctga ggtgtttaac ctcgaatcta tagaggtgct aaaagggccc gattctttgc
     7441 agtatggcca gtcaagcccc ggagggattg tcaatctcgt cgtcaaaaaa cccctctatg
     7501 agacctatgc ccagattgag ctagagacta cttctaacac ctcctatagt cccaaagtcg
     7561 atctaggggg tgcgctcaat gattccaaaa ctttgcgata tagactcgtg gcactcgctc
     7621 gacatgatga aggatttcga gatagtcatg tcaattctga tagggtcttt attgcgccaa
     7681 ctcttgccta tgacattagc gatgaccaca cgttcacgct cgtgagcgaa tatctggacg
     7741 agcgaacccc ctcctctttt gaaagctatg tcaatagcaa gggagagcta gtcgctgata
     7801 tcaagacgat catgtcgcat cctgatgaga agtttgacaa aacacaaaaa atcatcggtt
     7861 ttgatttaga tagccgcttt ggcacatgga agtcgaatct caaatatcga tatgtggact
     7921 atctaagaga taactacaat gtccacatcc cctacgccta tgtagaagcg accaatcaag
     7981 tgaggcgatt ctttgcaacg cagaaatatg acttcaccga gcacgcgctg caatacacgc
     8041 tcaataaaga gctggagatt ttcaatctca aaaacaaaat cacgatgggc gctgactttg
     8101 gccgtgcctc tacgactttc acgggatgga tggatatggg cacaatctat gcgctcaacc
     8161 tctccaatct caaatatgaa gccctcaccg atctctctga ccatccaagc gcggtgacct
     8221 atggaaacac aggagagaag atcaccacca ccaagaaagg aatctttgcg caggacaatc
     8281 tctatctttc agagaatctc atcctcagca caggggtgag atactccacg gtcaaatctg
     8341 acacaagcga taagagtagc gcttggacgc ctcaaattgg gctagtctat aagctcacgc
     8401 ccgaaacctc tctctacgcg aactactccg aatcgttcac gcctcaaagc gccacggata
     8461 tcaacggaaa gattctcgac cctgaggagg gagagggggt ggagcttggg attaagcaaa
     8521 agctttttgg tgacaggcta gcgctcaccg ctgcggtttt taaaatcgaa aaggtcaatg
     8581 tcgcgatgcc cgatcccatc aatcccctca aatcagtggc tagtggcaaa caggagagca
     8641 aagggtttga gtttgatgtg agtggtgata tcacttcaga ttggtctatg gcggcctcct
     8701 atggctacac ttcaacagaa gacaaagcaa ccaatcaagg caaagagctc tcagggattc
     8761 ctaaacacac ggcgaatctc ttcaccacgc actatcttac ggcgtttgga ttgccgcatt
     8821 tttatgtcgg gggtggcgtg cgatatcttg gcgagcgata cgccaatagc accaacacga
     8881 tcaagctcga ttcaagcctc atctatagtg cgatggtcgg atacagaaaa ggaaactgga
     8941 ggggcgcttt gagtgtgcag aatatcaccg atgaggtcta tgtcgagagt gcgagcaact
     9001 caagggtgag cgtgggcaca ccaagaacag tcgtggcgac tctggggtat ctcttttaat
     9061 atcccgccaa cagagccact cctaaaaaac gcccaatacg cctccttagc ttgtttgtaa
     9121 gagcaggaca gggaggccca acaagacaaa tctgcactcc ttagccaaat caatccaaag
     9181 aggatgtgct attcttatat ttaatatatt ttaatttaaa atgaaaaata agatagataa
     9241 aaccctagaa aataggcgat tttttgctaa aaattttaaa aaatgctcat aataaaagac
     9301 ctatagcaat atattaaaag tataatttga cttacaaatg aaagtgtatt aacataaatt
     9361 tgatagcgtt aattacttta ttaattttaa gtatttaatg cgatctattt attttaagga
     9421 tgggtttatg tctagattct tttctaaaat aacatcggtt gtgttattaa gcctgcttct
     9481 tgtattgggt gtgcaagccg ccacgattga agtgatcagt tcgggcgcat tctatgctac
     9541 gatggaggaa ttgaagcctc tttttgagaa aaaaacaggg cacgaagtcc accttcagtc
     9601 tggctcctca atgggtgcgt ctgaaacttc tatacccaat cgcttaaagc gtggagaaac
     9661 atttgatctt atcattttag cgagtggcca gcttgaaaag atgattgccg atggatatgc
     9721 gactaagggt agcagggttg atcttgtcca ctcttcaatt ggcatgatgg ttcgcaaggg
     9781 tgaaccaaaa ccagatatta gcacgcaagc agcttttgat aaagctttaa aagatgcaaa
     9841 atcaattggg tactctgcga gtgccagcgg cacacatctt gctgaaaaag tatttccagg
     9901 ctttggtgag agcgtcacta gcaaaacaaa gctgattgtg ggggatcgtg ttgcaacttg
     9961 ggttgggcgt ggtgatttgg aaataggttt tcagcaagta agcgaaatta caccttttac
    10021 aggggaaaag ggtagcgttg atctcgtggg acccattcct gctccctatc aaaaagtgac
    10081 tattttttct gtcggggttg ctaatggtag caaggagcca caagcagctc gtgagcttgt
    10141 agaatttctc acttcaaagg agaattactc tcgtttgatg gagcaaggat tagttcccgc
    10201 tgcgatggct gtagaaacag caaaataagc cctgttttga tgctgcataa gcccgattcg
    10261 atactggatt gggcttaaaa agttaggtgt tttataggtg tatgaaatta ataaaaatag
    10321 gatggagcac ggctaaataa cgcggaagaa aaaagagaag atgagtggtg gagtgtaggg
    10381 ggatcgaacc cctgacctcg acgctgccag cgtcgcgctc tcccagctga gctaacaccc
    10441 caaaaaccgc caaagcgatt aaagaggcgt aattctacaa gagagaagct taaaaattct
    10501 tagatttttc cttgtttttt gaggtagatc cagccgattc ctccgagcat gactaaaaga
    10561 gccgccatga taaggtggag tgattcttga attagggctt cattttgtcc aataaagtag
    10621 ccaagaagcg tgaggatgat cacccatatc cccgccccaa gccctgtaaa aaagagaaaa
    10681 atgggcagat tcatcctcgc caatcccgca ggaagagaga tgtattgacg caccacgggg
    10741 atgaggcgac cgctaaaggt ggagatatga ccatgcttgt ggaaaaactc ctccatcttt
    10801 c
//
