LOCUS       NZ_CP089331.1          10813 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP089331.1 Eggerthella lenta strain APC055-529-1D chromosome,
            complete genome.
ACCESSION   NZ_CP089331
VERSION     NZ_CP089331.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:04:05
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3295665
            Orig. end    :: 3306478
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3300665:3301478](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             335..1948
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 108.9; E-value: 5.7e-33)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2833"
                     /transl_table=11
                     /translation="MGHGVPMARVRGAERLDALRARWHHASLKTSFMVYMLGFLLLALV
                     MSTVTAGMFSGLQHRVIADAYEISGLYLYDAHNRTLVPARAVDIDENGSSVFVQTVRGE
                     MTEMPLTDLSSLVEITDASDYQYSPGTAYLYGSANDDALSVETPEAPDQTELTPAELPA
                     YDAKARDRFDAWLAANPDSPYTSFFDGDSQDGNTVGLLTSAVGYYVNTPPSEEAQALSS
                     ALELLTFLMFPLWFGLCIFAAARRFFGKRLQPGFDVLDRAASNIAEQNLEFSVSYDRDD
                     ELGHLASSFEAMRASLAESQRALWRTAEERKRLNAAFAHDLRTPLTILKGKIELLDAHV
                     QSGNVPADRLTASVASLAAQVERLERYVAAMSGLQKLEDRAVVARPTRFDSVAGMVEDA
                     GTGLAAHADRTFALSVSARCDRERPELCVDQAIVGEVAENLLNNAMRYASSQVDARLDV
                     RDGALVLMVEDDGPGFSNAALERGCAPFFSEVPSAEHFGLGLNIASLMCEKHGGGVTLE
                     NREGGGARVVARFSLDFCAE"
     PFAM_domain     1265..1468
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2833_0018"
                     /evalue="9.20E-08"
                     /label="ctg1_2833"
                     /locus_tag="ctg1_2833"
                     /protein_end="378"
                     /protein_start="310"
                     /score="32.1"
                     /tool="antismash"
                     /translation="RKRLNAAFAHDLRTPLTILKGKIELLDAHVQSGNVPADRLTASVA
                     SLAAQVERLERYVAAMSGLQKLE"
     PFAM_domain     1634..1930
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2833_0019"
                     /evalue="3.70E-11"
                     /label="ctg1_2833"
                     /locus_tag="ctg1_2833"
                     /protein_end="532"
                     /protein_start="433"
                     /score="43.6"
                     /tool="antismash"
                     /translation="GEVAENLLNNAMRYASSQVDARLDVRDGALVLMVEDDGPGFSNAA
                     LERGCAPFFSEVPSAEHFGLGLNIASLMCEKHGGGVTLENREGGGARVVARFSL"
     CDS             2017..2835
                     /locus_tag="ctg1_2834"
                     /transl_table=11
                     /translation="MEDTAPLRTSTVTLPPLPRTHGNAPDNATIATDRRSLLKKRAAVI
                     VGLLALTAGLAGFCVLYGPELLAFVADAPRFRAWVDETGWISRIVFVLANMAQVVFAFL
                     PGEPLELGAGYAFGFWEGTLWCLVASALGTAAVMALVRAFGIRIVGLFFSPDKITSMRW
                     LRDSRRFEMLLFLCFLIPGTPKDLLTYVAGLGSSSIGRIVAITTVGRIPSIVSSTLAAG
                     AFGDGNYLGAALVIALTAVLAAAGVIAYRQLAKRSDAAEDAASSADAMGA"
     PFAM_domain     2326..2661
                     /aSDomain="SNARE_assoc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09335.13"
                     /description="SNARE associated Golgi protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2834_0020"
                     /evalue="1.30E-12"
                     /label="ctg1_2834"
                     /locus_tag="ctg1_2834"
                     /protein_end="215"
                     /protein_start="103"
                     /score="48.3"
                     /tool="antismash"
                     /translation="LPGEPLELGAGYAFGFWEGTLWCLVASALGTAAVMALVRAFGIRI
                     VGLFFSPDKITSMRWLRDSRRFEMLLFLCFLIPGTPKDLLTYVAGLGSSSIGRIVAITT
                     VGRIPSIV"
     CDS             2962..4224
                     /locus_tag="ctg1_2835"
                     /transl_table=11
                     /translation="VSIGYASKTLAAPGARMQSVVQRLATPDRLAQAIDGNLRALDAAL
                     DYQAKNGIHLFRISSDVIPFGSSPVNALDWMRDFEPHLAALGRKARRHGIRLSMHPGQY
                     TVLNSPDADVVERAKLDLAYHAAFLDALGMDASGKIVLHVGGAYGDKPRALERFANAYA
                     TLPLAVRRRLVIENDDRLFTAQDVLALSRATGAPMVFDTLHHELNREPDAPDWRALLDE
                     AAATWKPEDGAQKMHYAQQAPGRRPGSHTDTIELAPFLAFYRSLAEHRTDSSFGMPDIM
                     LEVKDKNLSAIKCILCTSEHGRFSRLEREWARYKYAVLEHDQAAYLALRALLKDKRTWP
                     TVPFYEIVERALAAPVEPGSFRNAAQHVWGYVAPHATAREHAAFERLLEHDDRPAAKRK
                     LHALAEKYDQPYLLESYYFVL"
     aSDomain        3007..3828
                     /aSDomain="TIGR00629"
                     /aSTool="tigrfam"
                     /description="uvde: UV damage endonuclease UvdE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2835_0008"
                     /evalue="2.90E-51"
                     /identifier="TIGR00629"
                     /label="ctg1_2835"
                     /locus_tag="ctg1_2835"
                     /protein_end="289"
                     /protein_start="15"
                     /score="172.7"
                     /tool="antismash"
                     /translation="RMQSVVQRLATPDRLAQAIDGNLRALDAALDYQAKNGIHLFRISS
                     DVIPFGSSPVNALDWMRDFEPHLAALGRKARRHGIRLSMHPGQYTVLNSPDADVVERAK
                     LDLAYHAAFLDALGMDASGKIVLHVGGAYGDKPRALERFANAYATLPLAVRRRLVIEND
                     DRLFTAQDVLALSRATGAPMVFDTLHHELNREPDAPDWRALLDEAAATWKPEDGAQKMH
                     YAQQAPGRRPGSHTDTIELAPFLAFYRSLAEHRTDSSFGMPDIMLEVKDKNL"
     PFAM_domain     3040..3747
                     /aSDomain="UvdE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03851.16"
                     /description="UV-endonuclease UvdE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2835_0021"
                     /evalue="1.30E-60"
                     /label="ctg1_2835"
                     /locus_tag="ctg1_2835"
                     /protein_end="262"
                     /protein_start="26"
                     /score="205.1"
                     /tool="antismash"
                     /translation="PDRLAQAIDGNLRALDAALDYQAKNGIHLFRISSDVIPFGSSPVN
                     ALDWMRDFEPHLAALGRKARRHGIRLSMHPGQYTVLNSPDADVVERAKLDLAYHAAFLD
                     ALGMDASGKIVLHVGGAYGDKPRALERFANAYATLPLAVRRRLVIENDDRLFTAQDVLA
                     LSRATGAPMVFDTLHHELNREPDAPDWRALLDEAAATWKPEDGAQKMHYAQQAPGRRPG
                     SHTDTIELAPFLAF"
     PFAM_domain     3904..4215
                     /aSDomain="DUF1722"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08349.13"
                     /description="Protein of unknown function (DUF1722)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2835_0022"
                     /evalue="1.30E-14"
                     /label="ctg1_2835"
                     /locus_tag="ctg1_2835"
                     /protein_end="418"
                     /protein_start="314"
                     /score="54.5"
                     /tool="antismash"
                     /translation="KYAVLEHDQAAYLALRALLKDKRTWPTVPFYEIVERALAAPVEPG
                     SFRNAAQHVWGYVAPHATAREHAAFERLLEHDDRPAAKRKLHALAEKYDQPYLLESYYF
                     "
     CDS             4540..4911
                     /locus_tag="ctg1_2836"
                     /transl_table=11
                     /translation="MPSFPNPFAGNVDRKMTNTELMQALRIDIAGELEAIFLYDAHYQA
                     TDDPAAKAVLADIRDEEKAHMGELITLMRHLDPTETEFFLEGEGEVQEKLAELGIKTDG
                     EIAPAPAEPAPAPTVGDLS"
     PFAM_domain     4603..4764
                     /aSDomain="COQ7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03232.15"
                     /description="Ubiquinone biosynthesis protein COQ7"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2836_0023"
                     /evalue="1.90E-06"
                     /label="ctg1_2836"
                     /locus_tag="ctg1_2836"
                     /protein_end="75"
                     /protein_start="21"
                     /score="27.8"
                     /tool="antismash"
                     /translation="MQALRIDIAGELEAIFLYDAHYQATDDPAAKAVLADIRDEEKAHM
                     GELITLMRH"
     PFAM_domain     5001..5768
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2837_0024"
                     /evalue="5.30E-80"
                     /label="ctg1_2837"
                     /locus_tag="ctg1_2837"
                     /protein_end="256"
                     /protein_start="0"
                     /score="268.5"
                     /tool="antismash"
                     /translation="MDYLARESADLSDGLWNRIDETVIGTARAQLTCRRFLKVFGPLGA
                     GVTTVAVDGVNKEEVLEDGIGRIVGRTQLELPLFYEDFTLLSRDMEYAAQTGYPLDLSV
                     AIAAAKKASRREDDLILNGSKALGTDGLLTVKGSSKIKKSDWSQGENSFADITAGVAQL
                     AKTGYLGRYALVVSPDLFLDLQRLQPNTGLLEIDRIKKLIGDNVYMTSVMGPGKAVLVC
                     AEPEYLDLAIGLDLSVGYLELADFNHTFRIMETA"
     CDS             5001..5813
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2837"
                     /sec_met_domain="Linocin_M18 (E-value: 4.6e-81, bitscore:
                     269.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLARESADLSDGLWNRIDETVIGTARAQLTCRRFLKVFGPLGA
                     GVTTVAVDGVNKEEVLEDGIGRIVGRTQLELPLFYEDFTLLSRDMEYAAQTGYPLDLSV
                     AIAAAKKASRREDDLILNGSKALGTDGLLTVKGSSKIKKSDWSQGENSFADITAGVAQL
                     AKTGYLGRYALVVSPDLFLDLQRLQPNTGLLEIDRIKKLIGDNVYMTSVMGPGKAVLVC
                     AEPEYLDLAIGLDLSVGYLELADFNHTFRIMETAALRVKDPAAIVVFA"
     CDS             5986..7197
                     /locus_tag="ctg1_2838"
                     /transl_table=11
                     /translation="MAYRDLRKIFHGYPKTYATEYESRFNSDQSHKVGFDVSGSPAFFV
                     MTPEIYQAAIDAAKIDKEIYQLILSLPGKAIQSYRESNLIDEIVITNEIEGVRSTRREI
                     GDVLERLEENDKRGRFHGLVQKYQMLSREEDIAICTCADVRSIYDDLVLDEVARDNPDH
                     VPDGTLFRKGPVSVCDATGIPIHKGMEPESKITLCLEKALDILNDTDIEPIARVSLFHF
                     LFGYIHPFYDGNGRTNRFISSYVLSKEYEPLIGFRLSYAVKQDIEKYYRGYTVCEHPLN
                     KGDLTPFVIAFSEIIVSAMESMRNSLRELRNMLEEGERMAEIVFAKDEKAIEIASVLVT
                     AALFAFNGITMAELTYTFDASRQTMYKKLAPFKERGVLVAQKEGRKTYYRMDLDALRRL
                     ADQQ"
     PFAM_domain     6487..6723
                     /aSDomain="Fic"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02661.20"
                     /description="Fic/DOC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2838_0025"
                     /evalue="1.00E-11"
                     /label="ctg1_2838"
                     /locus_tag="ctg1_2838"
                     /protein_end="246"
                     /protein_start="167"
                     /score="45.7"
                     /tool="antismash"
                     /translation="TLFRKGPVSVCDATGIPIHKGMEPESKITLCLEKALDILNDTDIE
                     PIARVSLFHFLFGYIHPFYDGNGRTNRFISSYVL"
     CDS             complement(7218..8942)
                     /locus_tag="ctg1_2839"
                     /transl_table=11
                     /translation="VATLKEVAQVAVEARRDKGSGSGRRLREIERILRQHRVLSGLTPE
                     KATSLLEDLGPTFVKMGQIAANRSDVIPPAYADAFKRLRADVPPMPFSTVLATIEESLG
                     HPWRETFSCIEEKPLGSASIAQVHRARIAPHAVGDAGAGTGAAAVPLPADAPKAGSYVA
                     IKVRRPHVVEQMTQDLALIRQAVALVGLTRATDGIKLSLDDLVTELERTTRQELDFCVE
                     QHNLVRFRQFLDDQPGVESPRPYPHLSSDDVLVMDFVEGPMINDVPALRAMGLDPAKLG
                     QRLAESFVTQIVDNGFFHADPHPGNILVRGDDIVWIDLGMVGQLSALERALIGRMFRAV
                     AENDPYALMEALLGAVRSEGPVNHGRLLSQLGNLLVSYTTVNLADINVGSALMDVFGVL
                     QTQNLALPPSFTLLARGMVTIEGVLVDIAPDTSVIDIIAAHVKRRERTWEAFETKAREF
                     VSTAATSAQAAVRLPTQASHTLDMIDRGQVRVGADLGIPIDAIAALYSVSGTVAMALIS
                     AGLFIGSSLLATTNMHPQFLGVPLLGVLGYVGAFVLGAYVVWRNLVIRHRQKNEEKL"
     PFAM_domain     complement(7893..8696)
                     /aSDomain="ABC1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03109.18"
                     /description="ABC1 atypical kinase-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2839_0026"
                     /evalue="2.10E-57"
                     /label="ctg1_2839"
                     /locus_tag="ctg1_2839"
                     /protein_end="350"
                     /protein_start="82"
                     /score="194.1"
                     /tool="antismash"
                     /translation="LRADVPPMPFSTVLATIEESLGHPWRETFSCIEEKPLGSASIAQV
                     HRARIAPHAVGDAGAGTGAAAVPLPADAPKAGSYVAIKVRRPHVVEQMTQDLALIRQAV
                     ALVGLTRATDGIKLSLDDLVTELERTTRQELDFCVEQHNLVRFRQFLDDQPGVESPRPY
                     PHLSSDDVLVMDFVEGPMINDVPALRAMGLDPAKLGQRLAESFVTQIVDNGFFHADPHP
                     GNILVRGDDIVWIDLGMVGQLSALERALIGRMFRAVAENDPYALME"
ORIGIN
        1 tagccgtgct gggagcgcgc gtgaaggcgc atcttgcccg cgacaaccgc cagcacgtgc
       61 gcgccgaagt acgcttcgac ggcgacatcg ccatcgacta ccgctcgcgc accgtgacag
      121 cggccggacg gccggtggag ctgacgcggc gcgagttcga catcgtcgca ttcctgtcga
      181 agcatcccgg ccaagtgttc gatcgcgacc gcatccacga gcgcgtaggc ggttgggaaa
      241 acgagagcga ttcgcaggtg gtgaccgagc acatccggcg catccgcaag aagctggccg
      301 cagcgggcgc cgaacccgac ccggtggaaa cggtatgggg catggggtac cgatggcgcg
      361 cgtaaggggc gccgaacgcc tcgacgcctt gcgggcgcgt tggcaccacg cgtcgctcaa
      421 aacgtcgttc atggtgtaca tgctggggtt cttgctgctg gcgctggtga tgtccacggt
      481 gacggccggg atgttcagcg gattgcagca ccgggtgatc gcagacgcgt acgaaatctc
      541 ggggctctac ctctacgatg cgcacaaccg gacgctcgtt cccgcgcgcg ccgtggatat
      601 cgacgagaac ggcagcagcg tgttcgttca aaccgtgcgc ggcgagatga ccgagatgcc
      661 gctgacagac ttgtcgtcgc tcgtggagat cactgacgcg agcgattacc agtactcgcc
      721 ggggacggcg tatctgtatg gttccgccaa cgacgacgca ctcagcgtcg aaacgcccga
      781 agcgcccgac caaaccgagc tcacgcccgc cgagctgccc gcctatgacg cgaaagcgcg
      841 cgatcggttc gatgcctggc tggctgccaa ccctgatagc ccctacacgt cgttcttcga
      901 cggagacagc caggacggca acaccgtcgg actgctcact tccgcagtgg gttactacgt
      961 gaacacgccc ccatcggagg aggcgcaggc gctgtcctcg gcactcgagc tgctaacgtt
     1021 cctcatgttc ccactgtggt tcggcctatg catcttcgca gcggcgcggc gcttcttcgg
     1081 caagcgcctc caacctggat tcgatgtgct cgaccgagca gcgtccaaca tcgccgagca
     1141 gaacctcgag ttctccgtgt cgtacgatcg agatgacgag ctgggccatc tagcttcgtc
     1201 gttcgaagcc atgcgcgcct cgttggccga atcgcagcgc gcgctgtggc gcacggccga
     1261 ggagcgcaag cgcctgaacg ccgcgttcgc gcacgacctg cgcacgccgc tcaccatcct
     1321 caagggcaag atcgagctgc tggacgcgca cgtgcagtcc ggcaacgtgc ccgccgatcg
     1381 cctgacggcc tccgtcgcct cgctggccgc gcaggtggaa cgccttgagc gctacgtcgc
     1441 cgctatgagc gggctgcaaa agctggaaga ccgcgccgtc gttgcgcgcc cgaccaggtt
     1501 cgacagcgtg gcgggcatgg tggaggacgc cggaacgggg cttgctgcgc acgccgaccg
     1561 gaccttcgcg ctgtcggtga gcgcacgttg cgaccgcgag cggccagagc tatgcgtgga
     1621 tcaggccatc gtgggcgagg tggccgagaa cctgctgaac aacgccatgc gctatgcgtc
     1681 gtcccaagtg gacgctcgcc tcgacgtgcg tgacggcgcg ctggttctca tggtggaaga
     1741 cgacgggccg ggcttttcga acgccgcgct cgaacgcggt tgcgcgccct tcttcagcga
     1801 ggtgccctcg gcagagcatt tcggcctggg gctgaacatc gcgtcgctca tgtgcgagaa
     1861 gcacggcggc ggcgtaacgc tggagaaccg cgagggggga ggcgcgcgcg tggtcgcgcg
     1921 attctccctg gatttctgcg ccgagtagac agtcggtaga tatttgctcc gtaccatcgg
     1981 aagcgtaccg aacgcacccg agaaacggag catcccatgg aagacaccgc cccgctgcga
     2041 acttcgaccg tcaccctgcc cccgcttcct cgtacgcatg gcaacgctcc cgataacgcg
     2101 acgatcgcga cggaccggcg ttccctgctg aagaagcgcg ctgccgtgat cgtcgggctg
     2161 ctggccctga cggcggggct cgcagggttc tgcgtcctct acgggccgga gctgcttgcc
     2221 ttcgttgccg acgctccgcg cttccgcgcc tgggtggacg aaaccggctg gatcagccgc
     2281 atcgtgttcg tgctggccaa catggcgcag gtcgtgttcg cgttcctgcc cggcgaaccg
     2341 cttgagctgg gagcgggcta cgcgttcggc ttctgggaag gcacgctgtg gtgcctcgtg
     2401 gccagcgcct tgggaaccgc ggcggtcatg gcgctcgtcc gcgcattcgg aatccgcatc
     2461 gtcggcttgt tcttctcgcc cgacaagatc acgtcgatgc gctggctgcg cgactcccga
     2521 cgtttcgaaa tgctgctgtt cctgtgcttt ctcattcccg ggacgccgaa agacctgctc
     2581 acctatgtgg ccggactggg atctagctcc atcggacgca tcgtggccat caccacggta
     2641 ggtcgcatcc cctccatcgt ctcgtccacg ctggcggcgg gcgcgttcgg cgacggcaat
     2701 tacctggggg cggcgctcgt gatcgcactg acggcggtgc tggccgcggc gggcgtgata
     2761 gcgtaccggc agctggcgaa gcgcagcgac gcggccgagg atgcggcctc tagcgctgac
     2821 gcaatgggag cctaggcgcg cgccgagcgc cactccgtca cgggatcgtg ctccggcggt
     2881 gacctgggcg catcccgctt ccctccgcac gcgcgtaaga tgagccatcg tagcgcggaa
     2941 accggatcga agggaggcgt cgtgagcatc gggtacgcat cgaagacgct ggcagcgccc
     3001 ggcgcgcgca tgcaatcggt ggtgcagcgg ctggcgacgc ccgaccgcct ggcgcaggcg
     3061 atcgacggca acctgcgcgc gctggacgcc gccctcgact accaggcgaa aaacggcatc
     3121 cacctgttcc gcatcagctc ggacgtgatc cccttcgggt cgagccccgt gaacgcgctc
     3181 gattggatgc gcgacttcga gccgcatctg gccgcgctcg ggcgcaaggc gcggcgccat
     3241 ggcatccggc tgagcatgca ccccggccag tacaccgtgt tgaactcgcc cgatgccgac
     3301 gtggtggagc gggcgaagct cgacctggca taccacgcgg cgttcctcga cgcgctcggg
     3361 atggatgcga gcggaaagat cgtgctgcac gtgggcggcg cgtacggcga caagcctcgc
     3421 gcgctcgagc ggttcgccaa cgcgtacgcg acgctgcccc tcgcggtgcg ccgacggctc
     3481 gtcatcgaga acgacgaccg gctgttcacc gcccaggacg tgttggcgct cagccgtgca
     3541 accggagcgc ccatggtgtt cgacacgctg catcacgagc tgaaccgcga gcccgacgcg
     3601 ccggactggc gagcgctgtt ggacgaggcg gccgccacct ggaagcccga ggacggcgcg
     3661 cagaagatgc actacgcgca gcaagcccct ggtcgcaggc cgggcagcca caccgacacc
     3721 atcgagcttg cgccctttct cgcgttctac cgatcgctcg cagagcatcg gaccgacagc
     3781 tccttcggca tgcccgacat catgctggaa gtgaaggaca agaacctctc cgccatcaaa
     3841 tgcatcctct gcaccagcga gcacggccgc ttcagccggc tcgaacgcga atgggcgcgc
     3901 tacaagtacg ccgtgctcga acacgaccag gcagcctacc tcgccctgcg ggcgctgctc
     3961 aaggacaagc gcacgtggcc gaccgttccg ttctacgaga tagtcgaacg cgcgctggcc
     4021 gcacctgtgg aaccgggatc gttccgcaac gccgcgcagc acgtatgggg ctacgtggcg
     4081 ccgcacgcca ccgcgcgcga gcacgcggcg ttcgagcgcc ttctggagca cgacgatcgc
     4141 cccgccgcga agcgcaagct gcacgccctc gccgagaagt acgaccagcc ttacctgttg
     4201 gagtcctact acttcgtgct gtagccttct ttcgacttgc gcttgcgagg atgttttacg
     4261 cgaagcatcg gacgacgccc cttcgtcgtg ccctgacggc gatgcgaggc cccgcccttt
     4321 cctcagccgc agcgaacaag ggcgcttgag cgcttcgctc gcttgggcaa acaccgccga
     4381 gtaggttcgt ttataacgtg tagttattga gaataattat caataataat ggtatcgtta
     4441 catttcaatc ctgattatcg gagtatcata tcgggcagag agaagacctg aaccaccgcc
     4501 gatcacggcg gcgcgacgaa catgaaagag agggatcgta tgcccagttt ccccaatccg
     4561 tttgcaggca acgtcgaccg caagatgacg aacaccgagc tcatgcaggc gctccgtatc
     4621 gacatcgcgg gcgagcttga agccatcttc ctgtacgacg cccactatca ggcaaccgac
     4681 gacccggccg ccaaggccgt gctggccgac atccgcgacg aggagaaggc ccacatgggc
     4741 gagctcatca cgctgatgcg ccacctcgac cccacggaga cggagttctt cctggaaggc
     4801 gaaggcgaag tgcaggagaa gctggccgag ctgggcatca agaccgacgg cgaaatcgcc
     4861 ccggcgcccg cggagcccgc tcccgccccc accgtcggcg acctttccta acgcaaccga
     4921 cttccggcgc gcagccgccg acgaatgttt cacgtgcaac attcgtacgt gctgccgcct
     4981 tctcaagaaa ggagtccctc atggactatc tcgctcgcga atcggccgac ctttcggacg
     5041 gcctgtggaa ccgcatcgac gaaaccgtta tcggcaccgc ccgcgcccag ctgacctgcc
     5101 gtcgattcct caaggtgttc ggcccgctgg gcgccggcgt gaccaccgta gccgtcgacg
     5161 gcgtgaacaa ggaagaggtg cttgaggacg gcatcggccg catcgtcggc cgcacgcagc
     5221 tcgagctgcc gctgttctac gaggacttca ccctgctcag ccgcgacatg gagtatgccg
     5281 cgcagaccgg ctacccgctg gatctgtccg tggccatcgc cgccgccaag aaggcgtcgc
     5341 gccgcgagga cgacctcatc ctcaacggca gcaaggcgct gggcaccgac ggcttgctca
     5401 cggtgaaagg gtcgtcgaaa atcaagaaga gcgactggtc gcagggcgaa aacagcttcg
     5461 ccgatatcac cgccggcgtc gcccagctag ccaagaccgg ctacttgggc cgctacgcgc
     5521 tcgtggtgtc gcccgacctg ttcctcgact tgcagcgcct gcagccgaac accggtctgc
     5581 tggagatcga ccgcatcaag aagctcatcg gcgacaacgt gtacatgacc agcgtcatgg
     5641 gtcccggcaa ggccgtgctc gtgtgcgccg agcccgagta cctggatctt gccatcggcc
     5701 tggatctgtc ggttggctac ctggagctcg cggacttcaa ccacacgttc cgtatcatgg
     5761 aaacagccgc cctccgcgtg aaggaccccg ccgccatcgt ggtattcgcg taacgccgag
     5821 cgcgtccata aagcatttga gagcggcctg catttgatgc gggtcgctcg tttttgttgt
     5881 cacgttaact cattccgctg ttttacctat aatagagtta aatttgtagt ataattttaa
     5941 ctctattaga gtaaatcgat cgaatcgagt taaagaaggc tacacatggc gtatcgtgat
     6001 ctaagaaaaa tcttccacgg ttatcccaag acgtacgcta ccgaatacga gtccaggttc
     6061 aattccgacc agtcgcataa agtcggtttc gacgtatccg ggagccctgc gtttttcgtc
     6121 atgactccag agatctacca ggcggcaatc gatgctgcaa aaatcgacaa agagatctac
     6181 cagctcattc tctctttgcc tgggaaagcg atacaaagct atcgggagtc gaaccttatc
     6241 gatgaaatcg ttatcaccaa cgaaatcgaa ggcgtacgat ctacaaggcg cgaaatcgga
     6301 gacgtcctcg aacgactgga agaaaacgac aaacgtggac gcttccacgg tcttgttcaa
     6361 aaataccaaa tgctgagccg cgaggaagac atcgcaatct gcacctgcgc agatgtcaga
     6421 agcatatacg acgacttggt cttggacgag gttgcacgcg acaatccgga tcacgttccc
     6481 gacggaaccc tcttcagaaa aggccctgta tcagtatgcg acgccaccgg tatccccatt
     6541 cacaagggaa tggagccaga atcgaagatc actctttgcc ttgagaaagc gctcgatatt
     6601 ctgaatgata cggatatcga acctatcgct cgcgtatcgc tgttccactt tcttttcggc
     6661 tacatccacc ccttttacga cggaaacggc agaacaaaca gatttatcag cagttatgtt
     6721 ttgtcgaaag agtacgagcc attgattgga ttccggcttt cttatgccgt aaagcaggac
     6781 attgagaaat actatagagg gtacaccgtc tgcgaacacc ccttgaacaa gggcgatctg
     6841 accccgttcg tgatagcatt ttcggaaata atcgtttccg ccatggaaag catgcgcaat
     6901 tccctgaggg agctccgaaa catgctcgaa gagggcgaga ggatggcgga gatcgtgttc
     6961 gcaaaagacg agaaggccat cgaaatcgcc agcgttcttg tgacagctgc gctgttcgcc
     7021 ttcaacggga tcaccatggc ggaactcacc tacacgttcg acgcatcaag gcagactatg
     7081 tacaagaagc tcgctccctt caaagaacgc ggtgtgctcg tcgcgcaaaa agaaggacgt
     7141 aaaacgtact atcggatgga cttggatgcc ctcaggcgcc tcgccgatca gcagtagcag
     7201 agtagagttg cagctcgcta cagcttctcc tcgttctttt gcctgtggcg gatgacgagg
     7261 ttgcgccaca ccacgtaggc accgaggacg aacgcgccca cgtagcccaa cacgcccagc
     7321 aggggcacgc ccagaaactg cgggtgcatg ttcgtggtag caagcaggct cgatccgatg
     7381 aacagcccgg cggagatgag cgccatagcc accgtcccgc tgacggagta gagcgcggcg
     7441 atggcgtcga tcgggatgcc gaggtcggcg ccgacgcgaa cctggccgcg atcgatcatg
     7501 tcgagcgtgt gcgatgcctg ggtgggcaag cgcaccgcgg cctgcgcgga cgtcgccgcg
     7561 gtcgagacga actcgcgcgc cttggtttcg aacgcctccc aggtgcgctc gcggcgcttc
     7621 acgtgggcgg cgatgatgtc gatgacgctg gtgtcgggcg cgatgtccac cagcacgccc
     7681 tcgatggtga ccatgccgcg cgccagcagg gtgaacgaag gcggcagcgc caggttctgc
     7741 gtctgcagca cgccgaacac gtccatcagc gccgagccca cgttgatgtc ggccaggttc
     7801 accgtggtgt acgagaccag caggttgccc agctggctga gcagccgccc gtggttgacc
     7861 ggcccctccg agcgcacggc gcccagcagc gcttccatca gcgcatacgg atcgttctcg
     7921 gccacagcgc ggaacatgcg cccgatcagc gcgcgctcga gcgccgacag ctggcccacc
     7981 atccccaaat cgatccacac gatgtcgtcg ccgcgcacga ggatgttgcc cggatgcggg
     8041 tcggcatgga agaacccgtt gtccacgatc tgcgtcacga agctctcggc caggcgctgg
     8101 cccagcttcg ccggatcaag gcccatagcg cgcagggcgg gaacgtcgtt gatcatgggg
     8161 ccctcgacga agtccatgac cagcacgtcg tcggaactga ggtgcggata cgggcgcggg
     8221 ctttccactc ccggctgatc gtcgagaaac tggcggaacc gcacgagatt gtgctgctcg
     8281 acgcagaagt caagctcctg gcgcgtcgtg cgctccagct cggtgaccag gtcgtccagc
     8341 gacagcttga tgccgtcggt tgcacgggtg agccctacga gcgcaaccgc ctggcggatg
     8401 agcgcgagat cctgcgtcat ctgctccacc acgtgcggtc gacgcacctt gatggccacg
     8461 tacgaccccg ccttcggagc gtcggcaggc aacgggaccg ccgcggcgcc ggtgcccgct
     8521 cccgcatcgc caaccgcatg cggcgcgatg cgcgcccggt gcacttgggc gatggacgcc
     8581 gatccgagcg gcttctcctc gatgcacgag aacgtttccc gccacggatg ccccagcgat
     8641 tcctcgatgg tggcgagcac cgtggagaac ggcatgggcg gcacgtcggc gcgcagccgc
     8701 ttgaacgcgt cggcgtacgc gggcgggatg acgtcgctgc ggttcgccgc gatctgtccc
     8761 atcttcacga acgtcggccc caagtcctca agcaagctgg tcgccttttc cggcgtgagg
     8821 cccgacagca cgcgatgctg ccgcaggatg cgctcgatct cgcgcaggcg cctccccgac
     8881 cccgaccctt tgtcgcgtcg cgcctccacg gccacctgcg ccacttcctt gagcgtggcc
     8941 acgccgcacc tcctcgtctc gcctgttcaa cctacattcg acagcccagc gtaccatggc
     9001 accatgcggc gagtgcaccg gttgcccagc ggttatcgga cggatgccga gccggaggaa
     9061 gacgggcgga aacgcacgcc gccccggcct gcgcagaccg gggcggttga agggggcgcg
     9121 acgcggaggg aggggagaga acgcgtgcgc cccgtcggat tggatgatcg gtcgagcggc
     9181 cggcatgcgg gcgatcccgc atgccgggcc gacgccattg ccgcttacgc gtcgatcgtc
     9241 tcgacggcgt actgcccggc cagacggccg ccgcagtagg cgcacataag cgagtagcct
     9301 tcgtagtcgc agtacggggc gctcatcagc gtgccgttgt cggcgccggc cacgtacagg
     9361 ccggggatgg ccacgccctc gccgtcgatt gcttgcagac ggtcgttcgt gcggatgccg
     9421 ccgatggtca cccatgcgct gggctcatac tggaatgcgt agaacgggcc ggtggtcacg
     9481 ggctgcagga agcaagccgg cttgtagaac tgctcgtcgt tgccgtcggc gcagtagccg
     9541 ttgtactcgt ccagcgtctc gaccagctcg ggcgcgtcga tggcctgggc cagcgcctcg
     9601 atggtgtcgg ccttgaaagc ccagccggcg ctcacggcat catcgatgct gccctgcacg
     9661 ttctccagcg gcttgtcctt gagcgtcatc atgccggtgc gccagttcac ctcgtcggcg
     9721 ccgcacagcg tccacgcgtc cttgccggaa ttcaaaccgt ccacgtacgc ctggtcgacc
     9781 accgcgtagt acttgccgcc gaccagcgag atggccccgc ccagcgccag cggcagattc
     9841 gcgaacttgc cctcgttcga gaagcggcgg ccctggttgt tcaccagcag cgtgccgtag
     9901 atgccgatgg tgaacgcggc gctcttgcgg tcgtacaggc cgtcggcttt ctggttggag
     9961 ccggtgaact cgttgcccgc gatgccccac tgcgtggaca gctgaccgcc cgcagcctgc
    10021 accatgtcga tgccctcgcc cacggacagc acgttgccca gcgggttcac gaaggtgccg
    10081 aacttctcgc gcatcatgtc gacgttgccc aggaaaccgc ccgtggccac gatgacggcc
    10141 ttcgccttca cgtcggtcac gccgtcgccc tcgcactgca cacccgtgca tgcgccgtct
    10201 tccatgatga ggcgcttgcc cgccgtgttg aacaggaact cgcccccctt gctttccacg
    10261 aactcttgga ggggcttcat gcgatcctcg cccttggcct gcgtcttcga gtccttcggg
    10321 tcgctctgga agttggcgcg cacggacgca tgccctgcgc cgtagttgtc gggacgcagg
    10381 ccggtaggca cgccgaagtc gtcggtgaac tggtcgaccg tctcgccgga gatggcgacg
    10441 gctgccttga cggccgcagc gttcgtggac cagtgcgcgt actccataat atggttgaag
    10501 gcttcctcca ccgtgaactc gacgccggct tcctgctgca gcttcgagcc caccatgaac
    10561 gggccgcccg ccagcgagcc gttggccacg cccacgttac cgcccttctc gatgacgacg
    10621 acgctcttgc cggcgcgcac ggcttcgacc gcggcccaca tgcccgcgcc gcccgcgccc
    10681 acgatggcga tgtcgcattc cttcgtctga tcggcggtct gcatcgcgga agctgcgtcg
    10741 tcggtcgcgc ccttcgcgtc ggcgttcgcg ctgcttgacg cttgcggggc gcatccggca
    10801 agcgcggccg cgc
//
