LOCUS       NC_014376.1            21674 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014376.1 [Clostridium] saccharolyticum WM1, complete sequence.
ACCESSION   NC_014376
VERSION     NC_014376.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:21:46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 660315
            Orig. end    :: 681989
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21674
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[670315:671989]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11674
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21674
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21674
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             241..1215
                     /locus_tag="ctg1_586"
                     /transl_table=11
                     /translation="MELKHKVERIIKDGIWEAPEIPDGIPHGDMPGDKVEIGEVHRKKA
                     NIIFPQLLFKLSEVLKECESEKVVVTVCGGSGVGKSEIASLLSYYFNHLGIGSYTLSGD
                     NYPHRIPKYNDGERLHIFRESAIKAMVKDGTFNEERFKIIHRLQQVQDDANAVHTKKYS
                     WYKSYLLGGREGLKNYLGTEKEIAFGEIEEILTQFKNGKEEIWLKRMGRDDTELWYGKV
                     DFSGIHVMIIEWTHGNSDNYQGVDIPILLNSTPQETLAHRRARNRDGATDSPFTAMVLE
                     LEQEMLEAQAPKARIILSKSGEILTYEQYCRQMEESRGGGHEQ"
     CDS             1205..2908
                     /locus_tag="ctg1_587"
                     /transl_table=11
                     /translation="MNSKEDKFSVDYGVMLNAYPDSMGGTLSQITDFLKRPELAEVFRS
                     FYILPSIFNTDLDRGFSVIDYGLNERMADRKDLEAFKDLGIDLKLDFILNHSSVLSKEF
                     QDILKNGEKSRYRDFFIDWNKFWEGYGTMTEEGYIQPDEALIKDMFFRKPGLPILMVRL
                     PDGKNVPYWNTFYQEVQYKRLDQWDLMQAAEIQYAAAEDLARIVNQELQEGKKPSEIEF
                     ESYEKYRDCVVELLESGRRYLGQMDLNIRSPLVWEYYDNTLKTLSEYGAKIVRLDAFAY
                     APKAPGERNFLNDPGTWDLLQKVQDLADQYHLQLLPEIHSGYGEKTYELLAGKGYMTYD
                     FFLPGLIIHALESGSGEYLTGWAKELKVKKIKVVNMLGCHDGIPLLDLKGLIPDEEIEG
                     LIKTIVGRGGFVKNLHGQKNVYYQVNATYYSALGEDDKKMLLSRALQLFMPGKPQVWYL
                     DLFAGKNDYEAVKKAGAAGHKEVNRTNLSLVQIEEKMGLDVVKKQIEMLRFRNNFPAFG
                     FDSDMDIQAVGSEIDITWKKEGYEARLKADLKTCEYEITGYGQNGFVYPL"
     CDS             2886..3134
                     /locus_tag="ctg1_588"
                     /transl_table=11
                     /translation="MDLFIRFNYFVTDQSGFFDTLGFIKPDETNTDAVGFIRLYMLKKV
                     LDKHGNDRYCNIELVCANYTLWPVDSFLPLVCKLWDT"
     CDS             3228..4199
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 86.4; E-value: 3.1e-26)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_589"
                     /transl_table=11
                     /translation="MSATKQEKEIYGEQVQIVSRSDGCVVYRIADGSGDMMITSYFVFP
                     GIQLVYYDVHMGKCSIDYGVLGNVMEINHCREGRIECGYRDEFFYLTQGDLAVSKKGAA
                     GHDSCFPLNHYDGIAIVIEMDRVPGCMSCFLDDVNVRPCALMEKFCSNDKCFVARSKPC
                     LEHIFSELYAVPDSIKKGYYKVKILELLLFLSGMDLRDDQMEQRCFTKSQVGLAKDVCQ
                     YLTERMDRRVTISELADSFHVSQTALKNSFKGVYGVSVYSYIREQKMQAAALMLRRTDR
                     SVLEIAGMCGYDNGSKFAGAFRNVMGVTPNEYRNTKKEIQEA"
     PFAM_domain     3936..4172
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_589_0001"
                     /evalue="2.60E-20"
                     /label="ctg1_589"
                     /locus_tag="ctg1_589"
                     /protein_end="315"
                     /protein_start="236"
                     /score="72.5"
                     /tool="antismash"
                     /translation="LADSFHVSQTALKNSFKGVYGVSVYSYIREQKMQAAALMLRRTDR
                     SVLEIAGMCGYDNGSKFAGAFRNVMGVTPNEYRN"
     CDS             4393..4674
                     /locus_tag="ctg1_590"
                     /transl_table=11
                     /translation="MSVVIVGGNECMVRQYKELCQEYSCCAKVFTEIKGGLKNKIGKPD
                     LLVLFTSTMSHKMVRCALSETKGLDTVIARSHSSSMSALKNILREHAV"
     PFAM_domain     4396..4662
                     /aSDomain="DUF2325"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10087.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2325)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_590_0002"
                     /evalue="4.80E-30"
                     /label="ctg1_590"
                     /locus_tag="ctg1_590"
                     /protein_end="90"
                     /protein_start="1"
                     /score="103.6"
                     /tool="antismash"
                     /translation="SVVIVGGNECMVRQYKELCQEYSCCAKVFTEIKGGLKNKIGKPDL
                     LVLFTSTMSHKMVRCALSETKGLDTVIARSHSSSMSALKNILRE"
     CDS             4686..5237
                     /locus_tag="ctg1_591"
                     /transl_table=11
                     /translation="MSEEMLIRHCAPTLAGIKTGNMFSCPYRSREEIHDEVRRLNRVLA
                     PKGVRVLPLRYFKQRALIYLYRPSSLSRDLADGYASDLLKQYGYSLENPQRCVVQLVHR
                     LRTCPGFPHEIGLFLGYPPEDVQGFIENRACHCKCIGCWKVYGNEEKARQTFNRYKKCT
                     EVYFDQWSKGIAVERLTVAV"
     PFAM_domain     4701..5222
                     /aSDomain="DUF3793"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12672.9"
                     /description="Protein of unknown function (DUF3793)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_591_0003"
                     /evalue="3.70E-58"
                     /label="ctg1_591"
                     /locus_tag="ctg1_591"
                     /protein_end="179"
                     /protein_start="5"
                     /score="196.4"
                     /tool="antismash"
                     /translation="LIRHCAPTLAGIKTGNMFSCPYRSREEIHDEVRRLNRVLAPKGVR
                     VLPLRYFKQRALIYLYRPSSLSRDLADGYASDLLKQYGYSLENPQRCVVQLVHRLRTCP
                     GFPHEIGLFLGYPPEDVQGFIENRACHCKCIGCWKVYGNEEKARQTFNRYKKCTEVYFD
                     QWSKGIAVERL"
     CDS             5275..5700
                     /locus_tag="ctg1_592"
                     /transl_table=11
                     /translation="MSKIAVVYWSGTGNTEAMAAAVLEGAKERGADAEIFTPSEFDASM
                     MEALDAIAFGCPAMGAEVLEESEFEPMFSACLSKLTGKKAALFGSYGWGDGEWMRSWEE
                     TCKEAGVELVCDSVICNEAPDHEAAAACKALGAALAE"
     aSDomain        5284..5691
                     /aSDomain="TIGR01753"
                     /aSTool="tigrfam"
                     /description="flav_short: flavodoxin"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_592_0001"
                     /evalue="1.70E-40"
                     /identifier="TIGR01753"
                     /label="ctg1_592"
                     /locus_tag="ctg1_592"
                     /protein_end="139"
                     /protein_start="3"
                     /score="136.7"
                     /tool="antismash"
                     /translation="IAVVYWSGTGNTEAMAAAVLEGAKERGADAEIFTPSEFDASMMEA
                     LDAIAFGCPAMGAEVLEESEFEPMFSACLSKLTGKKAALFGSYGWGDGEWMRSWEETCK
                     EAGVELVCDSVICNEAPDHEAAAACKALGAAL"
     PFAM_domain     5290..5661
                     /aSDomain="Flavodoxin_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00258.27"
                     /description="Flavodoxin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_592_0004"
                     /evalue="7.20E-15"
                     /label="ctg1_592"
                     /locus_tag="ctg1_592"
                     /protein_end="129"
                     /protein_start="5"
                     /score="55.5"
                     /tool="antismash"
                     /translation="VVYWSGTGNTEAMAAAVLEGAKERGADAEIFTPSEFDASMMEALD
                     AIAFGCPAMGAEVLEESEFEPMFSACLSKLTGKKAALFGSYGWGDGEWMRSWEETCKEA
                     GVELVCDSVICNEAPDHEAA"
     CDS             5939..7372
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     34.1; E-value: 1.7e-10)"
                     /gene_kind="other"
                     /locus_tag="ctg1_593"
                     /transl_table=11
                     /translation="LNEKDFPEEKMEDTAAGSSLAGNKKKEEDEYEKICYVCRRPENVT
                     GPMVSMPGGMNLCHDCMQKAFDSVSQGGFDITKIQNMPYMNLNLSDLGSINKKDLEIPN
                     KQRVKKRSEKEPGQELKRKDIPAPHVIRRKLDDYVIGQEQAKKVISVAVYNHYKRVYLT
                     DSRKKDEEENVQIEKSNILMIGPTGSGKTYLVKTLARLLDVPLAIADATSLTEAGYIGD
                     DIESVVSKLLTAADNDVDKAERGIIFIDEIDKIAKKKSTSSRDVSGESVQQELLKLLEG
                     STVEVPVGSNQKNALTPMTAVSTENILFICGGAFPDLEDIIKERLKEKSSIGFSAELKD
                     RYEKDPNILSHVTNEDLRKFGMIPEFLGRLPITVTLESLDKDLLVRVLKEPKNAILKQY
                     KRLLELDEVNLVFEDEALEWIAEEALKKKTGARALRAIIENFMLDIMYEVPKDPNIGSV
                     VITRAYLDKNGGPLIQMRC"
     aSDomain        6035..7351
                     /aSDomain="TIGR00382"
                     /aSTool="tigrfam"
                     /description="clpX: ATP-dependent Clp protease, ATP-binding
                     subunit ClpX"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_593_0002"
                     /evalue="7.80E-150"
                     /identifier="TIGR00382"
                     /label="ctg1_593"
                     /locus_tag="ctg1_593"
                     /protein_end="471"
                     /protein_start="32"
                     /score="497.4"
                     /tool="antismash"
                     /translation="KICYVCRRPENVTGPMVSMPGGMNLCHDCMQKAFDSVSQGGFDIT
                     KIQNMPYMNLNLSDLGSINKKDLEIPNKQRVKKRSEKEPGQELKRKDIPAPHVIRRKLD
                     DYVIGQEQAKKVISVAVYNHYKRVYLTDSRKKDEEENVQIEKSNILMIGPTGSGKTYLV
                     KTLARLLDVPLAIADATSLTEAGYIGDDIESVVSKLLTAADNDVDKAERGIIFIDEIDK
                     IAKKKSTSSRDVSGESVQQELLKLLEGSTVEVPVGSNQKNALTPMTAVSTENILFICGG
                     AFPDLEDIIKERLKEKSSIGFSAELKDRYEKDPNILSHVTNEDLRKFGMIPEFLGRLPI
                     TVTLESLDKDLLVRVLKEPKNAILKQYKRLLELDEVNLVFEDEALEWIAEEALKKKTGA
                     RALRAIIENFMLDIMYEVPKDPNIGSVVITRAYLDKNGGP"
     PFAM_domain     6467..7054
                     /aSDomain="AAA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07724.16"
                     /description="AAA domain (Cdc48 subfamily)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_593_0005"
                     /evalue="9.60E-45"
                     /label="ctg1_593"
                     /locus_tag="ctg1_593"
                     /protein_end="372"
                     /protein_start="176"
                     /score="152.9"
                     /tool="antismash"
                     /translation="EKSNILMIGPTGSGKTYLVKTLARLLDVPLAIADATSLTEAGYIG
                     DDIESVVSKLLTAADNDVDKAERGIIFIDEIDKIAKKKSTSSRDVSGESVQQELLKLLE
                     GSTVEVPVGSNQKNALTPMTAVSTENILFICGGAFPDLEDIIKERLKEKSSIGFSAELK
                     DRYEKDPNILSHVTNEDLRKFGMIPEFLGRLPI"
     PFAM_domain     7073..7291
                     /aSDomain="ClpB_D2-small"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10431.11"
                     /description="C-terminal, D2-small domain, of ClpB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_593_0006"
                     /evalue="9.20E-15"
                     /label="ctg1_593"
                     /locus_tag="ctg1_593"
                     /protein_end="451"
                     /protein_start="378"
                     /score="54.5"
                     /tool="antismash"
                     /translation="LDKDLLVRVLKEPKNAILKQYKRLLELDEVNLVFEDEALEWIAEE
                     ALKKKTGARALRAIIENFMLDIMYEVPK"
     CDS             7448..7915
                     /locus_tag="ctg1_594"
                     /transl_table=11
                     /translation="MVFISIIVLLASLDLLIKSAIEDQDEAGFPKELEGSGGKILLQKN
                     HNAGFSFGCFKDHRSLVQMIPLAVASFIGGMLACLLQKKGNVWEKLALSVALGGAVSNL
                     YDRLVRHYVVDYFSIQYGRLKKVVFNLGDMFIFLGAGIMLIIEIIKAFKEQ"
     PFAM_domain     7463..7885
                     /aSDomain="Peptidase_A8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01252.20"
                     /description="Signal peptidase (SPase) II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_594_0007"
                     /evalue="1.40E-23"
                     /label="ctg1_594"
                     /locus_tag="ctg1_594"
                     /protein_end="146"
                     /protein_start="5"
                     /score="83.9"
                     /tool="antismash"
                     /translation="IIVLLASLDLLIKSAIEDQDEAGFPKELEGSGGKILLQKNHNAGF
                     SFGCFKDHRSLVQMIPLAVASFIGGMLACLLQKKGNVWEKLALSVALGGAVSNLYDRLV
                     RHYVVDYFSIQYGRLKKVVFNLGDMFIFLGAGIMLII"
     CDS             8102..9352
                     /gene_functions="other (smcogs) SMCOG1273:hypothetical
                     protein (Score: 363.2; E-value: 3.1e-110)"
                     /gene_kind="other"
                     /locus_tag="ctg1_595"
                     /transl_table=11
                     /translation="LDSSDYIQLLTLIFLVGVSAFFSSAETALTTVNKIRIRNLAEAGN
                     KNAATLIKILENQGKMLSAILVGNNVVNLTASSMSTTLVMSIWGSKAIGIGTGILTLVI
                     LVFGEISPKTISTLYSESISLKYAKVIYGFMTVMTPVIYLIQILSSGFLRFVHVNPNRK
                     LDAITEDELRTIVDVSHEEGVIESEERKIINNVFDFGDSVARDIMIPRIDMTLVEVNAA
                     YDELIDIFRQEMYTRIPVYEETNDNVIGIINMKDLLLVDRSDDFHIRNFLREPLYTYEY
                     KKTAELMLEMRQTCNNVVIVLDEYGATAGMITLEDLLEEIVGEIRDEYDEDEENELIEV
                     APYEYLVEGSMKLDDLNDRLELELESEDYDSIGGLIIGQLDRLPEQGEEVVYCGIRLVV
                     DELDKNRIDKVRMYLPH"
     PFAM_domain     8132..8668
                     /aSDomain="DUF21"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01595.22"
                     /description="Cyclin M transmembrane N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_595_0008"
                     /evalue="6.90E-52"
                     /label="ctg1_595"
                     /locus_tag="ctg1_595"
                     /protein_end="189"
                     /protein_start="10"
                     /score="175.7"
                     /tool="antismash"
                     /translation="TLIFLVGVSAFFSSAETALTTVNKIRIRNLAEAGNKNAATLIKIL
                     ENQGKMLSAILVGNNVVNLTASSMSTTLVMSIWGSKAIGIGTGILTLVILVFGEISPKT
                     ISTLYSESISLKYAKVIYGFMTVMTPVIYLIQILSSGFLRFVHVNPNRKLDAITEDELR
                     TIVDVSHEEGVIESEE"
     PFAM_domain     8738..8878
                     /aSDomain="CBS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00571.30"
                     /description="CBS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_595_0009"
                     /evalue="5.70E-05"
                     /label="ctg1_595"
                     /locus_tag="ctg1_595"
                     /protein_end="259"
                     /protein_start="212"
                     /score="23.6"
                     /tool="antismash"
                     /translation="DMTLVEVNAAYDELIDIFRQEMYTRIPVYEETNDNVIGIINMKDL
                     LL"
     PFAM_domain     8945..9067
                     /aSDomain="CBS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00571.30"
                     /description="CBS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_595_0010"
                     /evalue="9.90E-04"
                     /label="ctg1_595"
                     /locus_tag="ctg1_595"
                     /protein_end="322"
                     /protein_start="281"
                     /score="19.6"
                     /tool="antismash"
                     /translation="KKTAELMLEMRQTCNNVVIVLDEYGATAGMITLEDLLEEIV"
     PFAM_domain     9116..9340
                     /aSDomain="CorC_HlyC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03471.19"
                     /description="Transporter associated domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_595_0011"
                     /evalue="1.20E-22"
                     /label="ctg1_595"
                     /locus_tag="ctg1_595"
                     /protein_end="413"
                     /protein_start="338"
                     /score="79.8"
                     /tool="antismash"
                     /translation="EVAPYEYLVEGSMKLDDLNDRLELELESEDYDSIGGLIIGQLDRL
                     PEQGEEVVYCGIRLVVDELDKNRIDKVRMY"
     CDS             complement(9460..9819)
                     /locus_tag="ctg1_596"
                     /transl_table=11
                     /translation="MEKSKLQVTLRNLLITYILTGILLVVLALALYKFRLKEGQIRLGV
                     NAVYIIACLFGGVLMGKSIRNRRFFWGLLLGLLYFLVLLAVSFFLNKGLNGSLNQLLTT
                     MAICAVSGTAGGMLS"
     aSDomain        complement(9463..9795)
                     /aSDomain="TIGR04086"
                     /aSTool="tigrfam"
                     /description="TIGR04086_membr: putative membrane protein,
                     TIGR04086 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_596_0003"
                     /evalue="3.60E-28"
                     /identifier="TIGR04086"
                     /label="ctg1_596"
                     /locus_tag="ctg1_596"
                     /protein_end="119"
                     /protein_start="8"
                     /score="96.0"
                     /tool="antismash"
                     /translation="TLRNLLITYILTGILLVVLALALYKFRLKEGQIRLGVNAVYIIAC
                     LFGGVLMGKSIRNRRFFWGLLLGLLYFLVLLAVSFFLNKGLNGSLNQLLTTMAICAVSG
                     TAGGMLS"
     PFAM_domain     complement(9463..9801)
                     /aSDomain="DUF3792"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12670.9"
                     /description="Protein of unknown function (DUF3792)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_596_0012"
                     /evalue="4.10E-28"
                     /label="ctg1_596"
                     /locus_tag="ctg1_596"
                     /protein_end="119"
                     /protein_start="6"
                     /score="97.9"
                     /tool="antismash"
                     /translation="QVTLRNLLITYILTGILLVVLALALYKFRLKEGQIRLGVNAVYII
                     ACLFGGVLMGKSIRNRRFFWGLLLGLLYFLVLLAVSFFLNKGLNGSLNQLLTTMAICAV
                     SGTAGGMLS"
     CDS             10001..10147
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_597"
                     /sec_met_domain="TIGR03973 (E-value: 1.3e-25, bitscore:
                     86.9, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.3e-25, bitscore: 87.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHVKTLNSSTLKESMKKGGCGECQTSCQSACKTSCTVGNQSCEN
                     SNR"
     aSDomain        10004..10132
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_597_0004"
                     /evalue="1.40E-25"
                     /identifier="TIGR03973"
                     /label="ctg1_597"
                     /locus_tag="ctg1_597"
                     /protein_end="44"
                     /protein_start="1"
                     /score="86.9"
                     /tool="antismash"
                     /translation="KHVKTLNSSTLKESMKKGGCGECQTSCQSACKTSCTVGNQSCE"
     PFAM_domain     10004..10135
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_597_0013"
                     /evalue="5.40E-25"
                     /label="ctg1_597"
                     /locus_tag="ctg1_597"
                     /protein_end="45"
                     /protein_start="1"
                     /score="87.1"
                     /tool="antismash"
                     /translation="KHVKTLNSSTLKESMKKGGCGECQTSCQSACKTSCTVGNQSCEN"
     CDS             10280..11674
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_598"
                     /sec_met_domain="PF04055 (E-value: 9.6e-13, bitscore: 46.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.1e-14, bitscore: 51.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.8e-17, bitscore:
                     60.9, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 7.4e-26,
                     bitscore: 88.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIHQYINNGFHIIMDVNSGSVHSVDPVMYDAVKIAAGMVPEMEEP
                     QNLGEEVGQEVIRRLSEPYGETEVKEALEEIQYLIDRGELFTKDLYHDYVVDFKKRSTV
                     VKALCLHIAHDCNLACKYCFAEEGEYHGRRALMSFEVGKKALDFLIANSGNRRNLEVDF
                     FGGEPLMNWDVVKQLVEYGRKKEKEYNKNFRFTMTTNGVLLNDEIMEFCNREMSNVVLS
                     LDGRKEVNDRMRPFRSGKGSYDLIVPKFQKFAQLRGTKDYYIRGTFTRQNMDFAKDVLE
                     FADLGFSSMSIEPVVAQPSEEYAIREEDLPQILEEYDKLAVEYISRQKEGKGFHFFHFN
                     IDLNQGPCVAKRLSGCGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVDTGVTNLQIRD
                     EFKLCNVYAKEKCRDCFARFYCSGGCAANSNNFHGSITDVYEIGCEMQKKRIECAIMIK
                     AALAKE"
     aSDomain        10283..11659
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_598_0005"
                     /evalue="2.20E-236"
                     /identifier="TIGR03974"
                     /label="ctg1_598"
                     /locus_tag="ctg1_598"
                     /protein_end="460"
                     /protein_start="1"
                     /score="782.9"
                     /tool="antismash"
                     /translation="IHQYINNGFHIIMDVNSGSVHSVDPVMYDAVKIAAGMVPEMEEPQ
                     NLGEEVGQEVIRRLSEPYGETEVKEALEEIQYLIDRGELFTKDLYHDYVVDFKKRSTVV
                     KALCLHIAHDCNLACKYCFAEEGEYHGRRALMSFEVGKKALDFLIANSGNRRNLEVDFF
                     GGEPLMNWDVVKQLVEYGRKKEKEYNKNFRFTMTTNGVLLNDEIMEFCNREMSNVVLSL
                     DGRKEVNDRMRPFRSGKGSYDLIVPKFQKFAQLRGTKDYYIRGTFTRQNMDFAKDVLEF
                     ADLGFSSMSIEPVVAQPSEEYAIREEDLPQILEEYDKLAVEYISRQKEGKGFHFFHFNI
                     DLNQGPCVAKRLSGCGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVDTGVTNLQIRDE
                     FKLCNVYAKEKCRDCFARFYCSGGCAANSNNFHGSITDVYEIGCEMQKKRIECAIMIKA
                     A"
     PFAM_domain     10604..11002
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_598_0014"
                     /evalue="6.20E-14"
                     /label="ctg1_598"
                     /locus_tag="ctg1_598"
                     /protein_end="241"
                     /protein_start="108"
                     /score="52.8"
                     /tool="antismash"
                     /translation="CLHIAHDCNLACKYCFAEEGEYHGRRALMSFEVGKKALDFLIANS
                     GNRRNLEVDFFGGEPLMNWDVVKQLVEYGRKKEKEYNKNFRFTMTTNGVLLNDEIMEFC
                     NREMSNVVLSLDGRKEVNDRMRPFRSGKG"
     aSDomain        11345..11590
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_598_0006"
                     /evalue="2.90E-17"
                     /identifier="TIGR04085"
                     /label="ctg1_598"
                     /locus_tag="ctg1_598"
                     /protein_end="437"
                     /protein_start="355"
                     /score="60.9"
                     /tool="antismash"
                     /translation="CGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVDTGVTNLQIRDE
                     FKLCNVYAKEKCRDCFARFYCSGGCAANSNNFHGSIT"
     CDS             11689..13941
                     /locus_tag="ctg1_599"
                     /transl_table=11
                     /translation="MAKSHGQGRGTIRRVFFFMTQKHGKEQERRRVMKSNKGKGLLGLI
                     VSLALVGLFAYFGYTTMSDIKLGLDLAGGVSITYQAKEENPSAEDMKDTIYKLQQRVQN
                     YSTEAEVYQEGNNRINVDIPGVSDANTILEELGKPGSLIFADETGKTILNGNQVATAKP
                     VITENNGIKEYMVDLTFTEEGKNLFADVTTKNVGKRIAIIYDGKMYSNPVVREAITQGQ
                     CQISGMTSYEEAETLASTIRIGSLSLELEELRSNVVGAKLGQEAITTSLKAGAIGFAIL
                     AVFMVVVYLIPGIASVIALSIYVGIILVLLSAFEVTLTLPGVAGIILSVGMAVDANVII
                     FTRIKEEIGYGKTVKSAIQAGFNKALSAIIDGNVTTLIAAGVLFWRGSGTVKGFASTLA
                     IGIVLSMITALFITKFVLNMLFHLGFEDPKYYGIKKAGKVIRFLSKKKLWFAGSLLVIV
                     VGLAFLGVNKSQTGSILNYSMEFKGGTSTNVTFNEDMSLEKISSEVVPVVEGITKDADV
                     QTQKVAGTNEVIIKTRTLTVDEREALNKAMVDHFGVESEKITAESISGAISQEMKRDAM
                     IAVIIATICMLLYIWFRFKDIRFAGSAVLALVHDVLIVLTFYALLKWSVGSTFIACMLT
                     IVGYSINATIVIFDRIREYLKTQVKLGLEEVVNLSISQTLTRSINTSLTTFIMVFVLYI
                     LGVSSIREFALPLMVGIVCGTYSSVCITGSLWYVMTVQKKGKKETAKVTANHGKKS"
     aSDomain        12139..12936
                     /aSDomain="TIGR01129"
                     /aSTool="tigrfam"
                     /description="secD: protein-export membrane protein SecD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_599_0007"
                     /evalue="5.60E-92"
                     /identifier="TIGR01129"
                     /label="ctg1_599"
                     /locus_tag="ctg1_599"
                     /protein_end="416"
                     /protein_start="150"
                     /score="306.9"
                     /tool="antismash"
                     /translation="TILNGNQVATAKPVITENNGIKEYMVDLTFTEEGKNLFADVTTKN
                     VGKRIAIIYDGKMYSNPVVREAITQGQCQISGMTSYEEAETLASTIRIGSLSLELEELR
                     SNVVGAKLGQEAITTSLKAGAIGFAILAVFMVVVYLIPGIASVIALSIYVGIILVLLSA
                     FEVTLTLPGVAGIILSVGMAVDANVIIFTRIKEEIGYGKTVKSAIQAGFNKALSAIIDG
                     NVTTLIAAGVLFWRGSGTVKGFASTLAIGIVLSMITALFITKFV"
     aSDomain        12226..12918
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_599_0008"
                     /evalue="5.50E-64"
                     /identifier="TIGR00916"
                     /label="ctg1_599"
                     /locus_tag="ctg1_599"
                     /protein_end="410"
                     /protein_start="179"
                     /score="213.9"
                     /tool="antismash"
                     /translation="FTEEGKNLFADVTTKNVGKRIAIIYDGKMYSNPVVREAITQGQCQ
                     ISGMTSYEEAETLASTIRIGSLSLELEELRSNVVGAKLGQEAITTSLKAGAIGFAILAV
                     FMVVVYLIPGIASVIALSIYVGIILVLLSAFEVTLTLPGVAGIILSVGMAVDANVIIFT
                     RIKEEIGYGKTVKSAIQAGFNKALSAIIDGNVTTLIAAGVLFWRGSGTVKGFASTLAIG
                     IVLSMITAL"
     PFAM_domain     12433..12945
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_599_0015"
                     /evalue="1.30E-15"
                     /label="ctg1_599"
                     /locus_tag="ctg1_599"
                     /protein_end="419"
                     /protein_start="248"
                     /score="57.4"
                     /tool="antismash"
                     /translation="ELEELRSNVVGAKLGQEAITTSLKAGAIGFAILAVFMVVVYLIPG
                     IASVIALSIYVGIILVLLSAFEVTLTLPGVAGIILSVGMAVDANVIIFTRIKEEIGYGK
                     TVKSAIQAGFNKALSAIIDGNVTTLIAAGVLFWRGSGTVKGFASTLAIGIVLSMITALF
                     ITKFVLNM"
     aSDomain        13111..13851
                     /aSDomain="TIGR00966"
                     /aSTool="tigrfam"
                     /description="3a0501s07: protein-export membrane protein
                     SecF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_599_0010"
                     /evalue="1.20E-61"
                     /identifier="TIGR00966"
                     /label="ctg1_599"
                     /locus_tag="ctg1_599"
                     /protein_end="721"
                     /protein_start="474"
                     /score="206.6"
                     /tool="antismash"
                     /translation="LNYSMEFKGGTSTNVTFNEDMSLEKISSEVVPVVEGITKDADVQT
                     QKVAGTNEVIIKTRTLTVDEREALNKAMVDHFGVESEKITAESISGAISQEMKRDAMIA
                     VIIATICMLLYIWFRFKDIRFAGSAVLALVHDVLIVLTFYALLKWSVGSTFIACMLTIV
                     GYSINATIVIFDRIREYLKTQVKLGLEEVVNLSISQTLTRSINTSLTTFIMVFVLYILG
                     VSSIREFALPLMVGIVCGTYSSVCI"
     aSDomain        13240..13845
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_599_0009"
                     /evalue="2.00E-45"
                     /identifier="TIGR00916"
                     /label="ctg1_599"
                     /locus_tag="ctg1_599"
                     /protein_end="719"
                     /protein_start="517"
                     /score="153.2"
                     /tool="antismash"
                     /translation="QTQKVAGTNEVIIKTRTLTVDEREALNKAMVDHFGVESEKITAES
                     ISGAISQEMKRDAMIAVIIATICMLLYIWFRFKDIRFAGSAVLALVHDVLIVLTFYALL
                     KWSVGSTFIACMLTIVGYSINATIVIFDRIREYLKTQVKLGLEEVVNLSISQTLTRSIN
                     TSLTTFIMVFVLYILGVSSIREFALPLMVGIVCGTYSSV"
     PFAM_domain     13324..13875
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_599_0016"
                     /evalue="2.30E-55"
                     /label="ctg1_599"
                     /locus_tag="ctg1_599"
                     /protein_end="729"
                     /protein_start="545"
                     /score="187.0"
                     /tool="antismash"
                     /translation="AMVDHFGVESEKITAESISGAISQEMKRDAMIAVIIATICMLLYI
                     WFRFKDIRFAGSAVLALVHDVLIVLTFYALLKWSVGSTFIACMLTIVGYSINATIVIFD
                     RIREYLKTQVKLGLEEVVNLSISQTLTRSINTSLTTFIMVFVLYILGVSSIREFALPLM
                     VGIVCGTYSSVCITGSLWYVM"
     CDS             13969..15144
                     /locus_tag="ctg1_600"
                     /transl_table=11
                     /translation="MPGRPGQEKEMQMNYKIIARDGRAKRGSVTTVHGTVQTPVFMNVG
                     TVGAIKGAVSTDDLREIKTQVELSNTYHLHVRTGDKLIKEFGGLHRFMNWDRPILTDSG
                     GFQVFSLTGLRKIKEEGVYFQSHIDGHRIFMGPEESMQIQSNLASTIAMAFDECPPHPA
                     TREYMQNSVDRTTRWLERCRNEMARLNSLPDTLNKEQLLFGINQGGTFEDIRIAHAKTI
                     SAMDLDGYALGGLAVGESHEEMYRILEETVPYLPENKPTYLMGVGTPANILESVDRGVD
                     FFDCVYPSRNGRHGHVYTNHGKMNLFNIKYELDHKPIEEGCGCPACRSYSRAYIRHLLK
                     AKEMLGMRLCVLHNLYFYNTMMEEIRDAIENHRYGEYKEQKLDRMMAGQTS"
     aSDomain        14011..15123
                     /aSDomain="TIGR00430"
                     /aSTool="tigrfam"
                     /description="Q_tRNA_tgt: tRNA-guanine transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_600_0011"
                     /evalue="6.90E-148"
                     /identifier="TIGR00430"
                     /label="ctg1_600"
                     /locus_tag="ctg1_600"
                     /protein_end="385"
                     /protein_start="14"
                     /score="490.5"
                     /tool="antismash"
                     /translation="YKIIARDGRAKRGSVTTVHGTVQTPVFMNVGTVGAIKGAVSTDDL
                     REIKTQVELSNTYHLHVRTGDKLIKEFGGLHRFMNWDRPILTDSGGFQVFSLTGLRKIK
                     EEGVYFQSHIDGHRIFMGPEESMQIQSNLASTIAMAFDECPPHPATREYMQNSVDRTTR
                     WLERCRNEMARLNSLPDTLNKEQLLFGINQGGTFEDIRIAHAKTISAMDLDGYALGGLA
                     VGESHEEMYRILEETVPYLPENKPTYLMGVGTPANILESVDRGVDFFDCVYPSRNGRHG
                     HVYTNHGKMNLFNIKYELDHKPIEEGCGCPACRSYSRAYIRHLLKAKEMLGMRLCVLHN
                     LYFYNTMMEEIRDAIENHRYGEYKEQKLDRM"
     aSDomain        14011..15123
                     /aSDomain="TIGR00449"
                     /aSTool="tigrfam"
                     /description="tgt_general: tRNA-guanine family
                     transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_600_0012"
                     /evalue="3.00E-140"
                     /identifier="TIGR00449"
                     /label="ctg1_600"
                     /locus_tag="ctg1_600"
                     /protein_end="385"
                     /protein_start="14"
                     /score="465.2"
                     /tool="antismash"
                     /translation="YKIIARDGRAKRGSVTTVHGTVQTPVFMNVGTVGAIKGAVSTDDL
                     REIKTQVELSNTYHLHVRTGDKLIKEFGGLHRFMNWDRPILTDSGGFQVFSLTGLRKIK
                     EEGVYFQSHIDGHRIFMGPEESMQIQSNLASTIAMAFDECPPHPATREYMQNSVDRTTR
                     WLERCRNEMARLNSLPDTLNKEQLLFGINQGGTFEDIRIAHAKTISAMDLDGYALGGLA
                     VGESHEEMYRILEETVPYLPENKPTYLMGVGTPANILESVDRGVDFFDCVYPSRNGRHG
                     HVYTNHGKMNLFNIKYELDHKPIEEGCGCPACRSYSRAYIRHLLKAKEMLGMRLCVLHN
                     LYFYNTMMEEIRDAIENHRYGEYKEQKLDRM"
     PFAM_domain     14038..15117
                     /aSDomain="TGT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01702.20"
                     /description="Queuine tRNA-ribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_600_0017"
                     /evalue="4.40E-144"
                     /label="ctg1_600"
                     /locus_tag="ctg1_600"
                     /protein_end="383"
                     /protein_start="23"
                     /score="480.1"
                     /tool="antismash"
                     /translation="AKRGSVTTVHGTVQTPVFMNVGTVGAIKGAVSTDDLREIKTQVEL
                     SNTYHLHVRTGDKLIKEFGGLHRFMNWDRPILTDSGGFQVFSLTGLRKIKEEGVYFQSH
                     IDGHRIFMGPEESMQIQSNLASTIAMAFDECPPHPATREYMQNSVDRTTRWLERCRNEM
                     ARLNSLPDTLNKEQLLFGINQGGTFEDIRIAHAKTISAMDLDGYALGGLAVGESHEEMY
                     RILEETVPYLPENKPTYLMGVGTPANILESVDRGVDFFDCVYPSRNGRHGHVYTNHGKM
                     NLFNIKYELDHKPIEEGCGCPACRSYSRAYIRHLLKAKEMLGMRLCVLHNLYFYNTMME
                     EIRDAIENHRYGEYKEQKLD"
     CDS             15194..15490
                     /locus_tag="ctg1_601"
                     /transl_table=11
                     /translation="MLSATGGTMGIGFWVIYIAVIFGFMYFIAIRPQKREKKKQQEMFA
                     NIAIGDSVLTSSGFYGVIIDMTDDTVIVEFGNNKNCRIPMQKTAIVQVEKAQA"
     PFAM_domain     15236..15466
                     /aSDomain="YajC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02699.17"
                     /description="Preprotein translocase subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_601_0018"
                     /evalue="1.20E-26"
                     /label="ctg1_601"
                     /locus_tag="ctg1_601"
                     /protein_end="91"
                     /protein_start="14"
                     /score="92.5"
                     /tool="antismash"
                     /translation="VIYIAVIFGFMYFIAIRPQKREKKKQQEMFANIAIGDSVLTSSGF
                     YGVIIDMTDDTVIVEFGNNKNCRIPMQKTAIV"
     aSDomain        15236..15472
                     /aSDomain="TIGR00739"
                     /aSTool="tigrfam"
                     /description="yajC: preprotein translocase, YajC subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_601_0013"
                     /evalue="1.30E-20"
                     /identifier="TIGR00739"
                     /label="ctg1_601"
                     /locus_tag="ctg1_601"
                     /protein_end="93"
                     /protein_start="14"
                     /score="71.3"
                     /tool="antismash"
                     /translation="VIYIAVIFGFMYFIAIRPQKREKKKQQEMFANIAIGDSVLTSSGF
                     YGVIIDMTDDTVIVEFGNNKNCRIPMQKTAIVQV"
     CDS             15958..17304
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 241; E-value:
                     4.7e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_602"
                     /transl_table=11
                     /translation="MKMSMFMEKSLAALLAAGMTVSLMGCGGQTTESAQTETAQQTTTA
                     QGSSAGSETSGGEVTLEFQQWWGVELPDGVLKEICDGFTEQSGVKIELLSNPYADTKTQ
                     IAAGAAAGTMADVVGLDGSWVYDFAKQGSITNMTELMSADGYDDGQLSDQIKVEGKTYM
                     IPVVNFAYPMYVNKTLLESAGISEIPKTWGEFTEACKKVSAANKGAAGWAIPLSTESPS
                     GIQNNFMSWLWASGGIMLKDGKPALTDNPLMADTVDFVKGLFDAGVVAPGAYSMKEADM
                     VEEFTNGRVAFMTDSLAHLTTIKKEAPDLKFEFMPVPVKEGYTGKSGMDVANWGIGIAE
                     NCEHKAEAMKFVEYLMSPEVNARLAVYANAFPGNINAKPDYSKADELFVKAYELYQQCY
                     AINEFTGLPTSEELMRQFDEQLQLSIDGDTASTADMLSATQEIWQGAFQ"
     PFAM_domain     16186..17040
                     /aSDomain="SBP_bac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01547.27"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_602_0019"
                     /evalue="7.50E-33"
                     /label="ctg1_602"
                     /locus_tag="ctg1_602"
                     /protein_end="361"
                     /protein_start="76"
                     /score="114.9"
                     /tool="antismash"
                     /translation="KEICDGFTEQSGVKIELLSNPYADTKTQIAAGAAAGTMADVVGLD
                     GSWVYDFAKQGSITNMTELMSADGYDDGQLSDQIKVEGKTYMIPVVNFAYPMYVNKTLL
                     ESAGISEIPKTWGEFTEACKKVSAANKGAAGWAIPLSTESPSGIQNNFMSWLWASGGIM
                     LKDGKPALTDNPLMADTVDFVKGLFDAGVVAPGAYSMKEADMVEEFTNGRVAFMTDSLA
                     HLTTIKKEAPDLKFEFMPVPVKEGYTGKSGMDVANWGIGIAENCEHKAEAMKFVEYLMS
                     PEVN"
     CDS             17368..18294
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 267.1; E-value:
                     2.9e-81)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_603"
                     /transl_table=11
                     /translation="LAKERETTKKESSGKTLQAMKRKREPYLYLLPTIVLMLLLLIIPI
                     CMVVRYSFFDNVIVKKDPVFAGLKNYAMILSDKTFFVAVKNTLFFVGASVIVHMFLGML
                     FAILLNTRYIGINLKAFFRVIYVLPWMFTASVIAILWKMMMNPNGIINYLLQITNLTSS
                     HIEWLGSRNFALFSVTLINIWAGYPFYMVSILAGLQGIPTDLYEASAIDGANAVQQFIR
                     ITIPQLKPIIISLFMLDFVWTIQQFALIWMTTGGGPINATEMISTFIYKRGFSKYQYSQ
                     ASASAVILLVVCSVIAVFYVRHQRERD"
     PFAM_domain     17671..18276
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_603_0020"
                     /evalue="1.30E-17"
                     /label="ctg1_603"
                     /locus_tag="ctg1_603"
                     /protein_end="303"
                     /protein_start="101"
                     /score="64.2"
                     /tool="antismash"
                     /translation="GMLFAILLNTRYIGINLKAFFRVIYVLPWMFTASVIAILWKMMMN
                     PNGIINYLLQITNLTSSHIEWLGSRNFALFSVTLINIWAGYPFYMVSILAGLQGIPTDL
                     YEASAIDGANAVQQFIRITIPQLKPIIISLFMLDFVWTIQQFALIWMTTGGGPINATEM
                     ISTFIYKRGFSKYQYSQASASAVILLVVCSVIAVFYVRH"
     CDS             18297..19133
                     /gene_functions="transport (smcogs) SMCOG1069:putative ABC
                     transporter permease protein (Score: 268.6; E-value:
                     9.5e-82)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_604"
                     /transl_table=11
                     /translation="MVGKKKWYIKLLIMILLGAGALFSGFPILWMLLSSLKPNGEIFAW
                     PPIWISENFSLKAYSSIFHNPEKVRFFINSYCIAMLVVILTLIIGILASYSFSRFNFPG
                     KSVINTLIVSVQAVPPITLLIPYLSLIVSLKLYNTFGALILTYMLFTLPYAILMITGYM
                     NTLPKDLDEAVMIDGGSRFVALWTVLVPVSVPGLVSVGMYTFMQAWNEYLFALALTKTN
                     EMRTVPVGISLLMGQHAYEWNQMMSMSVLGSLPVLMLFLFFQRYFIAGMTAGAVKN"
     PFAM_domain     18555..19109
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_604_0021"
                     /evalue="6.40E-16"
                     /label="ctg1_604"
                     /locus_tag="ctg1_604"
                     /protein_end="271"
                     /protein_start="86"
                     /score="58.7"
                     /tool="antismash"
                     /translation="LIIGILASYSFSRFNFPGKSVINTLIVSVQAVPPITLLIPYLSLI
                     VSLKLYNTFGALILTYMLFTLPYAILMITGYMNTLPKDLDEAVMIDGGSRFVALWTVLV
                     PVSVPGLVSVGMYTFMQAWNEYLFALALTKTNEMRTVPVGISLLMGQHAYEWNQMMSMS
                     VLGSLPVLMLFLFFQRYFIAGM"
     aSDomain        19188..20033
                     /aSDomain="TIGR00167"
                     /aSTool="tigrfam"
                     /description="cbbA: ketose-bisphosphate aldolase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_605_0014"
                     /evalue="1.80E-81"
                     /identifier="TIGR00167"
                     /label="ctg1_605"
                     /locus_tag="ctg1_605"
                     /protein_end="282"
                     /protein_start="0"
                     /score="271.6"
                     /tool="antismash"
                     /translation="MLLNMKELLAAANENNFAVPAFNISSYAMFNGIMEASEEEHAPVI
                     ISIHPDELSHIGTDIIQAIRQRAYKTKIPVCIHLDHGSSFEQIMIAIQAGYTSVMIDGS
                     SLPFEENIAVCKKVCEAAHGADVSVEGELGTIGTTDSAETENQVIIYTKPDDAAKFVEE
                     TGVDTLAIAIGTCHGLYPAGMKPELKLDLLKEIKSKVSIPLVLHGGSNNPDKEIGESVA
                     LGVNKINISSDIKAAYYMKMREVLKDGSLREPNMIEPPCIEAMKEVAYHKIRLFKADGK
                     A"
     CDS             19188..20045
                     /locus_tag="ctg1_605"
                     /transl_table=11
                     /translation="MLLNMKELLAAANENNFAVPAFNISSYAMFNGIMEASEEEHAPVI
                     ISIHPDELSHIGTDIIQAIRQRAYKTKIPVCIHLDHGSSFEQIMIAIQAGYTSVMIDGS
                     SLPFEENIAVCKKVCEAAHGADVSVEGELGTIGTTDSAETENQVIIYTKPDDAAKFVEE
                     TGVDTLAIAIGTCHGLYPAGMKPELKLDLLKEIKSKVSIPLVLHGGSNNPDKEIGESVA
                     LGVNKINISSDIKAAYYMKMREVLKDGSLREPNMIEPPCIEAMKEVAYHKIRLFKADGK
                     AARY"
     PFAM_domain     19197..20030
                     /aSDomain="F_bP_aldolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01116.22"
                     /description="Fructose-bisphosphate aldolase class-II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_605_0022"
                     /evalue="4.20E-91"
                     /label="ctg1_605"
                     /locus_tag="ctg1_605"
                     /protein_end="281"
                     /protein_start="3"
                     /score="305.4"
                     /tool="antismash"
                     /translation="NMKELLAAANENNFAVPAFNISSYAMFNGIMEASEEEHAPVIISI
                     HPDELSHIGTDIIQAIRQRAYKTKIPVCIHLDHGSSFEQIMIAIQAGYTSVMIDGSSLP
                     FEENIAVCKKVCEAAHGADVSVEGELGTIGTTDSAETENQVIIYTKPDDAAKFVEETGV
                     DTLAIAIGTCHGLYPAGMKPELKLDLLKEIKSKVSIPLVLHGGSNNPDKEIGESVALGV
                     NKINISSDIKAAYYMKMREVLKDGSLREPNMIEPPCIEAMKEVAYHKIRLFKADGK"
     CDS             20193..21551
                     /locus_tag="ctg1_606"
                     /transl_table=11
                     /translation="MGNGIYSMRGRADRMKAEEKYIETFEQIEPLIRRRIEKNAFTALG
                     YTSNLDVLCDFQIEVFNELLSRSLPNGDLAGMKASKEITDMEGFLETIVYFCTHGIGGE
                     VDISDFGIIRDTFEVKKGMGGTATQGAMALAAVTCPSIIHLTDDSKEVCDILNSPYIYT
                     VSNKGELIHTDQITQTAEQEIHYIIQFKKGDVICLGSQKITIPASNRLIITKITVNEAL
                     PFSDSFFTYVETHAANIKSNVLSSFNAIQDKGILEQRLAYVKEHIKKYKANNEAGIVYF
                     EDAHYHNKEIRQVCLETLYPYVDILSLNEEELEYTLSMYDFPIEINDIHSCIKGADYIK
                     ERFSVKKGIIVHTKDYSMYLGETLSGDIEKGLMLGNMLATAKAVNGWYGTKEQIREVIK
                     LPLSEKGMRNRELTAKEHFPWEVVFVPSKYIDKPRYTIGLGDSFVAGVQLCFE"
     PFAM_domain     20316..21539
                     /aSDomain="ADP_PFK_GK"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04587.17"
                     /description="ADP-specific Phosphofructokinase/Glucokinase
                     conserved region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_606_0023"
                     /evalue="3.20E-73"
                     /label="ctg1_606"
                     /locus_tag="ctg1_606"
                     /protein_end="449"
                     /protein_start="41"
                     /score="246.8"
                     /tool="antismash"
                     /translation="TALGYTSNLDVLCDFQIEVFNELLSRSLPNGDLAGMKASKEITDM
                     EGFLETIVYFCTHGIGGEVDISDFGIIRDTFEVKKGMGGTATQGAMALAAVTCPSIIHL
                     TDDSKEVCDILNSPYIYTVSNKGELIHTDQITQTAEQEIHYIIQFKKGDVICLGSQKIT
                     IPASNRLIITKITVNEALPFSDSFFTYVETHAANIKSNVLSSFNAIQDKGILEQRLAYV
                     KEHIKKYKANNEAGIVYFEDAHYHNKEIRQVCLETLYPYVDILSLNEEELEYTLSMYDF
                     PIEINDIHSCIKGADYIKERFSVKKGIIVHTKDYSMYLGETLSGDIEKGLMLGNMLATA
                     KAVNGWYGTKEQIREVIKLPLSEKGMRNRELTAKEHFPWEVVFVPSKYIDKPRYTIGLG
                     DSFVAGVQL"
ORIGIN
        1 gattatgaaa taagccacca ttatatcaga agctttactt ctgatatctc cggttcccat
       61 ggcagcaata tgtataagct gcttaatgaa atttctgaac aatggggatc tgttgccgga
      121 tttttgatgg aatgcgggat ttccatggat gagctgtctc tcctgattga aaagtttgta
      181 atgccctgtg aatttaatgg gtaaatgaaa aggtttaaat ggaaagcgag gctgtgaaat
      241 atggaattga aacataaggt tgaacgtata atcaaagacg ggatatggga agcacctgaa
      301 ataccggatg ggattcccca cggagacatg cctggggata aggttgaaat cggggaagta
      361 catagaaaaa aggcaaatat catttttccg caactgcttt tcaagttgtc agaggtttta
      421 aaggaatgtg aatctgagaa agttgttgtg acagtatgcg gtggttccgg cgttggtaaa
      481 tcagagatcg cttctttgct gtcctattat tttaatcacc tgggaatcgg aagctatacc
      541 ctatccggag acaattatcc tcacagaatc ccaaagtaca acgatgggga acgccttcat
      601 atattccggg aatcagcaat caaagccatg gtaaaagacg ggacatttaa cgaggagcga
      661 tttaaaataa ttcaccggct tcagcaggtt caggatgatg caaatgctgt acatacaaag
      721 aaatactcat ggtataaatc ttatcttctt ggaggaaggg aaggtttaaa gaattacctt
      781 ggaacagaaa aagaaattgc tttcggtgag attgaggaga ttcttaccca gtttaagaat
      841 ggaaaagaag agatctggtt aaagcgcatg ggcagagatg atacagaact ttggtatggt
      901 aaggtggatt tttccgggat ccatgttatg atcattgaat ggacccatgg aaacagtgat
      961 aattatcagg gagtagacat tcccattctt cttaacagca ccccgcagga gactttggcc
     1021 catcgaagag caagaaaccg ggatggagcc actgacagcc cctttacggc tatggttctt
     1081 gaactggaac aggaaatgct ggaggctcag gccccaaaag cccggatcat cctttcgaaa
     1141 agcggagaaa tattaactta tgaacagtat tgcaggcaga tggaagagag cagaggaggc
     1201 ggccatgaac agtaaggaag acaaattttc tgttgattat ggagtgatgc tcaatgccta
     1261 tcctgacagc atgggcggta ctttgtctca aattacggat tttttaaaaa ggcctgaatt
     1321 agcggaggta tttcgttcgt tttatatttt gccaagtatt ttcaacaccg atctggaccg
     1381 gggattttca gtaattgatt atgggttaaa tgaacggatg gcggacagaa aggatcttga
     1441 agcgttcaaa gacctgggga ttgacttaaa gctggatttt attctgaacc attcttctgt
     1501 gttatccaaa gagttccagg atattttaaa aaacggagag aaatccaggt acagggattt
     1561 ctttattgac tggaacaagt tttgggaagg ttatggaacc atgacagagg aaggctatat
     1621 tcagccggat gaagcactta ttaaagatat gttttttcgg aagccgggtc ttccgatttt
     1681 aatggtgcgc ctgcctgatg gaaaaaatgt accttactgg aatacttttt atcaggaagt
     1741 acagtacaaa aggttggatc aatgggatct gatgcaggca gcagaaatac agtatgcagc
     1801 ggcagaggat ctggcccgta tcgtaaacca ggaattacag gaggggaaaa aaccttctga
     1861 gatagagttt gaaagttacg aaaaatacag ggactgtgtg gtggaactgc tggaatcagg
     1921 acggaggtat ttgggacaaa tggacttgaa tatccgttcc ccgctggtct gggaatatta
     1981 tgacaatacg ttaaaaaccc tttctgaata cggtgccaaa atcgttcgcc tggatgcatt
     2041 tgcctatgcc cccaaggctc cgggagaaag gaatttttta aatgatccgg gaacctggga
     2101 tctgctgcag aaggtgcagg acctggcgga tcaatatcat ttgcagctgc tgccggaaat
     2161 acattccggc tacggagaaa aaacctatga gctgttggct ggaaaaggct atatgaccta
     2221 tgactttttc cttccgggcc ttattatcca cgcattggaa agcggcagcg gggaatatct
     2281 gacgggctgg gcaaaggaac tgaaggtaaa aaagatcaaa gtggtaaata tgctgggatg
     2341 tcatgatgga attccccttt tagacttaaa gggactgatc cctgatgaag aaattgaagg
     2401 attaattaag accattgtgg gacggggcgg gtttgtcaaa aatctccatg gacagaaaaa
     2461 tgtttattac caggtaaacg ccacatacta cagcgctctt ggggaagatg ataaaaagat
     2521 gctgctgtca agagctctgc agctttttat gcctggaaaa ccccaggttt ggtatctgga
     2581 tctttttgca ggtaaaaatg attatgaggc tgtgaaaaag gcaggggcag caggacataa
     2641 ggaggtgaac cgtaccaatc tgtctctggt gcagatagaa gagaaaatgg gacttgatgt
     2701 ggtcaaaaag cagattgaga tgctgcggtt ccgaaataac tttcctgcat ttggttttga
     2761 ttctgatatg gatattcagg ccgttggctc tgaaattgat attacatgga agaaagaagg
     2821 gtatgaagcc aggctaaagg cagatttaaa gacctgcgaa tatgaaataa ccggatatgg
     2881 gcagaatgga tttgtttatc cgctttaatt atttcgttac ggatcaatca ggcttttttg
     2941 acacccttgg atttataaag cctgatgaaa ccaacacaga cgctgtgggt ttcatcaggc
     3001 tttatatgtt aaaaaaagta cttgacaaac atgggaatga caggtattgt aacattgagt
     3061 tagtttgtgc taactatacg ctttggccag ttgattcctt cctgccattg gtatgtaaat
     3121 tgtgggatac ttaatgtccg atttcctgca aaattgaatc caaggcatac ccaaatgaaa
     3181 atggaaggca atattaaaaa aggaagtatg tcccgggaga tggtattatg agcgctacaa
     3241 agcaggaaaa agagatatac ggcgaacagg tacagattgt ttcccgttca gacggctgcg
     3301 tcgtttaccg tattgccgat ggaagcggag atatgatgat caccagttat ttcgtgttcc
     3361 ccggaatcca gttggtctat tacgatgtac atatgggaaa atgttccata gactatgggg
     3421 ttctcggaaa tgtgatggag atcaatcatt gccgggaagg gcgcatagag tgcggatacc
     3481 gggatgaatt tttttatctc acccagggcg atctagcagt cagcaaaaag ggtgccgcag
     3541 gtcacgactc ctgttttcct ctcaaccact atgatgggat tgccattgtc attgaaatgg
     3601 acagggtacc tgggtgcatg tcctgctttc tggatgatgt aaacgtgcgc ccctgcgccc
     3661 ttatggaaaa attctgcagc aatgacaaat gctttgtcgc acggtcaaaa ccctgccttg
     3721 aacacatttt ttcagagctt tatgccgtgc ctgacagcat aaaaaagggc tactataaag
     3781 tcaagatact ggaacttctg ttgtttttaa gcggcatgga tctaagggat gaccagatgg
     3841 aacagcgctg ctttacaaaa tcccaggtcg gccttgccaa ggacgtgtgc cagtatctta
     3901 cagagcgcat ggaccgccgg gtgacgattt ctgaactggc ggatagtttt cacgtttccc
     3961 agacggccct taagaacagt tttaagggag tgtatggcgt atctgtttac tcttacatca
     4021 gggaacagaa aatgcaggca gcagccctga tgctgcgccg gacagaccgg tccgtactgg
     4081 aaatcgcagg gatgtgcggc tatgacaacg gcagtaaatt tgcaggagca ttccgcaatg
     4141 tcatgggcgt gacgcccaat gaatatagaa atacaaaaaa agagatacaa gaagcatgac
     4201 tgtccgggaa tgggcaaaag gcagtgaccc gttgggggaa tatgtccgtt tggagccttc
     4261 ttctttcttt ttggagtgga aaggacctgg ctttttgggt aaaatataaa acaatcatta
     4321 acagcgcctc ggaggcgcat atactttaat atttagttag ctaaaactaa cttaaggatt
     4381 ggaggtaatc ccatgagcgt agtgatcgtt ggaggtaatg aatgcatggt tcggcaatac
     4441 aaagagctgt gccaggaata tagctgctgt gcaaaagtct ttacggagat aaagggcggg
     4501 ctgaaaaata aaatcggcaa accggatttg ctggtgcttt ttaccagcac catgtcccat
     4561 aaaatggtgc gctgcgcttt gagtgaaaca aaagggctgg ataccgtaat tgcccggtct
     4621 cactccagtt ccatgtccgc cctgaaaaat atcctgagag aacatgccgt ataggaggaa
     4681 acaatatgtc agaagaaatg ctgatccggc actgtgctcc cacattggcc ggaattaaaa
     4741 ccggaaatat gttttcctgt ccctaccggt ccagagaaga gatccatgat gaggtaagac
     4801 ggctgaaccg cgttcttgca ccgaaagggg tcagggtttt accgttgcgc tactttaagc
     4861 agagggcttt gatctatctt tatcgtccaa gcagcttaag ccgggatctg gctgacggat
     4921 atgcctctga tttgctgaaa caatatgggt attctttaga aaaccctcag cgctgtgtgg
     4981 tccagttagt tcacaggctg cgcacctgcc ccggatttcc tcacgagatt ggcttgtttc
     5041 ttggctatcc gccggaggat gttcagggct tcatcgaaaa cagggcctgc cactgcaaat
     5101 gcattggatg ctggaaagtt tacggcaatg aagaaaaggc aaggcagacc tttaaccggt
     5161 ataaaaagtg tacagaggtt tattttgacc agtggtcaaa gggaatagct gttgaacggc
     5221 ttaccgtagc cgtttgatat agaatgattg agcaggaaag gttggttata cattatgagt
     5281 aaaattgcag tagtttattg gagcggaacc ggaaataccg aggcaatggc agcagccgtc
     5341 ctggaaggtg caaaggaaag gggcgcagat gccgaaattt tcaccccttc tgaatttgat
     5401 gcttctatga tggaagccct ggatgccatt gcttttggct gtcctgccat gggtgcagag
     5461 gttttggagg aaagtgaatt tgaacccatg ttctctgcct gcctgtcaaa gcttaccggg
     5521 aaaaaggcgg cactgttcgg atcctatggc tggggagatg gtgaatggat gcgttcctgg
     5581 gaagagacct gcaaagaagc aggtgtggag cttgtttgtg acagcgtgat ctgcaatgaa
     5641 gcaccagacc atgaggcggc tgcagcctgc aaagcacttg gggcagctct ggcagaatag
     5701 caaaacagat tccggttcct tgattgtgaa ataagggaga tatgatctga cagcatggaa
     5761 aatttatcta ttcaattttc catgctgttt tttcgtgcat ggttttgcgg tcgctgactg
     5821 gtattaaaag aaagaattaa aaaaaactaa attgcaggtc cgcacttgta agagcctttt
     5881 aaatgcttta taataatctg gtatcggtgc ataattacag atagaaggag attacagctt
     5941 gaacgagaag gattttccgg aagaaaagat ggaagataca gctgccggca gctctctggc
     6001 cggcaacaag aaaaaggaag aagatgagta tgaaaaaatc tgctatgtgt gccgcaggcc
     6061 ggagaatgta accgggccta tggtttccat gccgggcgga atgaatctat gccatgactg
     6121 tatgcagaag gcatttgatt ctgtatctca gggcggattt gatataacaa agattcagaa
     6181 tatgccttat atgaacctga atttaagtga tcttggcagt ataaataaaa aggatctgga
     6241 gatacccaat aagcagaggg tgaaaaaacg atccgaaaaa gagcctggac aggaactgaa
     6301 acgaaaggat attccggcgc ctcatgtcat cagaaggaag ctggatgatt atgtaatcgg
     6361 tcaggaacag gccaaaaagg tgatttccgt agccgtttat aatcattaca aaagagtata
     6421 cttaacggat tccaggaaaa aggatgaaga agaaaatgtg cagatcgaaa agtccaacat
     6481 attaatgatc ggacctacgg gaagcggaaa gacttacctg gtaaaaacac tggcaaggct
     6541 tcttgatgtt ccgctggcta ttgccgacgc cacctctctt acagaagccg gatatatcgg
     6601 cgatgacata gaaagtgtgg tttctaagct gctgacggcg gctgacaatg atgtggacaa
     6661 ggcggaacgt ggtattattt tcattgatga gatcgataaa attgcaaaaa agaagagcac
     6721 aagcagcagg gatgtaagcg gggagtctgt acagcaggag cttttgaagc ttttagaggg
     6781 aagtacggtg gaagtaccgg taggctccaa ccagaaaaat gcacttaccc caatgactgc
     6841 agtcagcact gagaacattc tttttatctg cggcggagcg tttcctgatc tggaggatat
     6901 aatcaaggaa cggctgaagg aaaaatcgtc cattggtttt tccgcagaat taaaggatcg
     6961 ttatgagaag gatcctaata tcctgtctca tgtaacaaat gaagatctgc gcaaatttgg
     7021 catgataccg gaatttttag gacgtctgcc tattacggta accctggaat ccctggataa
     7081 ggacctgctg gtccgggtgc tgaaagaacc taagaacgct atattaaagc aatataaaag
     7141 gcttctggag cttgatgagg tgaatcttgt ctttgaagat gaggcattgg aatggatcgc
     7201 agaagaagct ctgaagaaaa agaccggagc aagagcgcta agagccatca tagaaaattt
     7261 catgctcgat attatgtatg aggttcccaa ggatcccaac atcggatccg ttgtcattac
     7321 aagagcttac ctggataaaa acggcggccc cctcatccag atgaggtgct gatgatgcgg
     7381 gaattcccgg acaaaggata aaaaactcaa agaagtggag ataataagga cggaaggagt
     7441 gtgggtcatg gtatttatca gtatcatcgt attactggct tccctggatc ttctcataaa
     7501 aagtgccatt gaggatcagg atgaagccgg ctttccaaag gaactggagg gaagcggcgg
     7561 aaagatcttg ctgcaaaaga atcataatgc cggtttttcc tttggctgct ttaaggatca
     7621 ccggtccctg gtacagatga ttccccttgc ggtggcgtcc tttatcggcg gaatgctggc
     7681 atgccttctt caaaaaaagg ggaacgtctg ggaaaaactg gccttgtccg ttgccctggg
     7741 aggcgcggtc agcaatttat atgacaggct ggtccgccat tatgtggtgg attatttcag
     7801 cattcagtat ggaagactta aaaaggtagt attcaatctg ggagatatgt ttatctttct
     7861 gggagccgga attatgctta ttatagaaat aattaaggct tttaaagaac agtgacacgg
     7921 aaaaaagcgg ctgtcttctt gacatggccg cttttctatt gtagaatcaa tgacaaagtt
     7981 gaagcatcgt tcagccttgg atttgtgaac atcgtgccct gcttcaccgg gcatggggat
     8041 atgcaggcgg atgccctagg atcacagata taaaaaattt aaaaaacagg agttgatatt
     8101 tttggattcg agtgactata tacagttgct tacgttgatt tttttagttg gagtgtcggc
     8161 atttttctca tcggctgaga ctgcccttac tacggtgaac aagatcagaa tcaggaattt
     8221 agcggaagca ggcaataaga atgcagcaac gctgattaag attttagaaa accagggtaa
     8281 gatgctcagt gcgattctgg tcggtaacaa tgtggtaaac ttaactgctt cttccatgtc
     8341 caccaccctg gtcatgagca tttggggcag taaggccata ggcattggaa ccggtatcct
     8401 tactctggtc attctggtgt tcggcgagat ttccccgaaa accatctcta ctttgtattc
     8461 cgaatcaata tctttaaaat atgcgaaagt aatttatggt tttatgaccg tcatgacgcc
     8521 ggtcatttat ctgattcaga tactttcttc aggctttttg cgctttgtcc atgtgaatcc
     8581 taaccggaag ctggatgcga tcacagagga tgaactgcgg acaatcgtgg atgtaagcca
     8641 tgaggaaggc gtgattgagt cggaagaaag aaaaatcatc aacaacgtgt ttgactttgg
     8701 tgattccgtg gcacgggaca ttatgatccc ccgcattgac atgaccctgg tggaggttaa
     8761 tgccgcttat gatgaactga tcgatatttt ccggcaggaa atgtacacca ggattccggt
     8821 atatgaggaa accaatgaca atgtaatcgg cattattaac atgaaggatc tgcttctggt
     8881 tgacaggagc gatgactttc acatcaggaa ttttttaaga gagcctctct atacatacga
     8941 gtataaaaag actgcggagc ttatgttgga gatgcgccag acctgtaata atgttgtcat
     9001 tgttctggat gaatacggag caacagcagg aatgattacc ctggaggact tactggaaga
     9061 aatcgttgga gagatcaggg atgagtatga tgaggatgaa gaaaatgagc tgattgaggt
     9121 ggcgccctat gaatatctgg tggagggctc tatgaagctt gatgacttaa atgaccggct
     9181 ggagctggag ctggaatccg aggattatga ttccatcggc ggcctgatca tcggacagct
     9241 tgaccggctc ccggaacagg gggaggaggt tgtctattgc ggaatccgtc ttgttgtaga
     9301 tgagctggac aagaacagga ttgataaggt gcggatgtat ttgccgcact aggccttttc
     9361 ccggcggcgc cttccgctcc ttaaacggaa ggcgggaaga tagggagaga aaagcatatg
     9421 gcttttctct ccctattgct ctttttaaag ccccgcccgt taactgagca tcccccctgc
     9481 agttccgctg actgcgcaaa tggccatggt ggtgaggagc tggttcaagg agccgtttaa
     9541 tcctttgttt aagaaaaagg atacggctaa cagcaccagg aaatatagaa gccccagcaa
     9601 aaggccccag aagaatcttc tgttccgtat gctttttccc attaagactc ccccaaagag
     9661 acatgcgata atataaaccg cattgacacc caggcgtatc tgtccttctt tcagccggaa
     9721 tttataaagt gctaaggcca ggaccaccag caggattccg gtcagtatgt aggtgataag
     9781 aaggtttctc agtgtgacct gaagctttga tttttccatt tgactactcc ttatgtcttg
     9841 tcttatggtt cagtatattc tatgggtatg gcggatattc ttggatgtcc ccataataaa
     9901 atcctttcgg cccgttctcc ctggggtaaa tcatcttgca ctcactgaaa acatgtggta
     9961 taatctcaaa gaattaggca aatacaggag gtgtaagtat atgaaacacg tgaagacatt
    10021 aaattccagt acattaaaag agtccatgaa aaaaggcggc tgcggcgagt gccagacttc
    10081 ctgccagtca gcctgcaaaa catcctgtac agtaggaaac cagagctgcg agaacagcaa
    10141 ccgttaattt tttaactgta tagaacagcc ataaggcaga taagcagatg cccctacggt
    10201 cgttacgacg gtaggggttc cttcgcttgt ctgcccaaaa ccgattatag gttaatttat
    10261 tcaattaagg agaatacaag tgattcatca atatattaac aacggcttcc atattattat
    10321 ggatgtcaac agcggttccg ttcattcggt ggatccggtc atgtatgacg cggtgaagat
    10381 tgcagcaggc atggtgccgg agatggaaga gcctcagaac ctgggagaag aggttggaca
    10441 agaagtcatc cgccgtcttt ctgaaccata cggagaaaca gaggtaaagg aagccctgga
    10501 ggaaatccag tatcttatcg acaggggaga gctgtttaca aaggatctgt atcacgatta
    10561 cgtagtcgat tttaaaaagc ggagcacagt ggtaaaagca ctttgcttac atattgctca
    10621 tgactgcaac ctggcctgca aatattgctt tgcggaagag ggggaatacc atggccggag
    10681 ggcgctgatg tcctttgaag tggggaaaaa ggccctggac tttctcattg ccaattccgg
    10741 caaccgaagg aatctggaag tggatttctt tggcggcgag ccgctgatga actgggatgt
    10801 agtaaaacag cttgttgaat acggccggaa aaaagagaaa gaatataata agaacttccg
    10861 ctttaccatg accaccaacg gcgttctgtt aaacgatgag atcatggaat tctgtaaccg
    10921 ggaaatgagc aatgtggtct taagtcttga tggccgtaaa gaggtcaatg acaggatgcg
    10981 tcctttccgc agcggaaagg gcagctatga cctgatcgtt cccaaattcc agaagtttgc
    11041 tcagcttaga gggactaagg attattatat caggggcact tttacccgcc agaatatgga
    11101 ttttgcaaag gatgtcctgg aatttgcgga tcttggcttt tcaagcatgt ccatagagcc
    11161 tgtggtagcc cagccgtcag aggaatatgc catcagggaa gaagatcttc ctcagatcct
    11221 agaggaatat gataagcttg cagtggaata catcagcagg caaaaggaag gaaaagggtt
    11281 tcatttcttc cattttaata ttgatttgaa tcaggggccc tgcgtggcaa agcgcctgtc
    11341 cggctgcggt tcggggacgg agtatctggc agtaactccc tggggagatc tttatccatg
    11401 ccaccagttt gtcggtgagg aaaaattcct tctcggcaat gtagatacag gtgtgacaaa
    11461 tttacagatc cgtgatgagt ttaagctttg caatgtctat gccaaggaga agtgcaggga
    11521 ttgctttgca agattttact gcagcggagg ctgtgcggcc aattccaata actttcatgg
    11581 aagcatcacg gatgtttatg aaatcggttg tgaaatgcag aagaaacgga ttgaatgcgc
    11641 cattatgatc aaggcagctt tggccaaaga gtaagaagga gccgcattat ggccaaaagc
    11701 catgggcaag gaaggggaac tatccggcgg gtattcttct tcatgaccca aaagcatggc
    11761 aaggaacagg aaaggagaag agtgatgaaa agtaacaaag gcaagggcct gttagggctg
    11821 attgtttcac tggcattggt tggattattt gcttattttg gctataccac gatgagcgac
    11881 attaagctag gtctggatct ggcagggggg gtcagcatta cttaccaggc aaaagaagaa
    11941 aatcccagcg ctgaagatat gaaagatacc atttataagc tgcagcaaag ggttcagaat
    12001 tacagcacag aggctgaggt ctaccaggaa ggaaacaacc ggattaatgt tgatattcca
    12061 ggtgtctcag atgccaatac aatattggaa gagcttggaa agccaggttc tctgattttt
    12121 gcagatgaaa ccggtaaaac catattaaac ggaaatcagg tggcaacggc aaagccggta
    12181 atcaccgaga ataacggcat caaggaatat atggtggatc tgacctttac agaggaagga
    12241 aagaatctat tcgcagatgt taccaccaag aatgtgggaa aacggattgc cattatctat
    12301 gacggcaaaa tgtattccaa tcctgtggtc agagaggcca ttacccaggg acaatgccag
    12361 atcagcggca tgacctctta tgaggaagcg gaaacactgg cttccaccat ccgcatcggt
    12421 tccctttctc tggaactgga agagcttcgc tccaatgtag taggagccaa gctgggacag
    12481 gaggccatta ccaccagttt aaaggctggc gccattggtt ttgccattct ggcagtattt
    12541 atggtagtgg tatatttaat cccaggaatt gcttccgtga ttgcattatc catttatgtg
    12601 ggtattattt tagtccttct gtctgcattt gaagtgactc tgacccttcc gggtgtcgca
    12661 ggtattattc tatctgtggg gatggcggtg gatgcaaatg ttattatttt cacacgtatc
    12721 aaagaagaaa tcggttatgg caagacggtt aagtctgcca ttcaggcagg attcaataaa
    12781 gcgctgtccg caatcattga cggaaacgta accaccctga tcgcggcagg cgttctgttc
    12841 tggagaggct ccggtacggt aaagggcttt gcctccaccc tggcgatcgg tattgtttta
    12901 tccatgataa cggctctctt tattacgaaa ttcgttttaa acatgctgtt ccacttaggc
    12961 tttgaggatc ccaagtatta tggaatcaag aaagcaggaa aggtgatccg tttcctctcc
    13021 aaaaagaagc tgtggtttgc gggttctctg cttgtgatag ttgtaggtct tgcatttttg
    13081 ggagtcaata aatcccagac aggaagcatt ttaaattaca gcatggagtt taagggcggt
    13141 acttccacca acgtgacctt taatgaggac atgtccctgg aaaagatatc atcggaagta
    13201 gtgcctgtag tagaaggcat aacaaaggat gcggatgttc agacccagaa ggttgcaggt
    13261 accaatgaag tgatcattaa gaccagaacc ttgaccgtgg atgagcgtga agccctgaat
    13321 aaggccatgg tggatcattt cggcgtagag tcggaaaaga tcactgcgga aagcatatcc
    13381 ggagccatca gccaggaaat gaagcgggat gccatgattg ccgtaatcat cgctaccatc
    13441 tgcatgcttc tttatatctg gttccgcttc aaggatatcc ggtttgctgg aagcgctgtc
    13501 cttgccctgg tgcatgacgt tctcatcgtg ctgacctttt atgccctgtt aaagtggtcc
    13561 gttggctcta cctttattgc atgcatgctg accattgtag gttattccat caatgccacc
    13621 attgtgatct ttgaccgtat ccgggagtat ttaaagaccc aggtaaagct tgggctggaa
    13681 gaagttgtga acttaagtat cagccagacc cttacaagaa gcatcaatac ctccctgacg
    13741 acctttatca tggtgtttgt tctgtatatc ctgggagtgt cctccatacg tgaatttgct
    13801 ttgccgctga tggttggtat cgtatgcggt acgtattctt ccgtatgcat aacaggttct
    13861 ctgtggtatg tgatgacggt tcaaaaaaag gggaaaaagg aaacggcaaa agtaactgct
    13921 aaccacggaa agaaatctta agaaagggac gccctggggg tatccctcat gcccggaaga
    13981 cctgggcagg aaaaggaaat gcaaatgaat tataagatta ttgcaaggga tggacgtgca
    14041 aaacggggat cggtgaccac cgtccacggt acggtccaga ccccggtgtt catgaatgtg
    14101 ggtacggtgg gagccattaa gggggctgtt tctacggatg accttcgtga gatcaaaacc
    14161 caggtggagc tgtcaaacac ctatcatctt catgtccgaa ccggcgataa attaattaag
    14221 gaatttggcg gtctccaccg gtttatgaat tgggaccgcc ccattctcac tgactccgga
    14281 ggatttcagg tgttttccct gaccggctta cggaaaataa aggaggaagg ggtttacttc
    14341 cagtcccata ttgacgggca cagaatcttc atgggtccgg aggagagtat gcagatccag
    14401 tccaatctgg catctaccat agccatggcc tttgacgaat gccctcctca tccggccacc
    14461 agggaatata tgcagaacag tgtagaccgt accaccagat ggctggaacg gtgccggaac
    14521 gagatggcaa ggctcaattc actgccggat accttaaata aggagcagct tctgttcggc
    14581 attaatcagg gcggaacctt tgaggacatc cggatcgccc atgccaaaac catttctgcc
    14641 atggacttag acggttatgc cttaggcggc cttgctgtgg gagaaagtca tgaggaaatg
    14701 taccggatct tagaggagac ggttccgtat ctcccggaga ataagcccac ctatctgatg
    14761 ggtgtgggaa cccctgccaa cattttagag tctgtggaca ggggagtgga ctttttcgac
    14821 tgcgtttatc cgtcaagaaa cggacgtcac ggtcatgtgt acaccaatca tggaaaaatg
    14881 aatttattca atatcaaata tgaactggat cataagccca ttgaagaagg ctgcggatgt
    14941 ccggcctgcc gttcctacag cagagcctat atcaggcatc ttctaaaggc aaaagaaatg
    15001 cttggcatga gattatgtgt cttgcataat ttgtattttt ataatacaat gatggaagag
    15061 atccgcgacg caatcgagaa tcaccgttat ggggagtaca aggaacagaa gcttgaccgc
    15121 atgatggcgg ggcagacttc ctgaaaaggg gggacaagca ggcggcggat cgttatataa
    15181 ggaggaaatg gttatgttat cagcaacggg cggtactatg ggcattggtt tctgggttat
    15241 ttacatcgca gtaatctttg gtttcatgta ttttatcgca atcagaccgc agaagagaga
    15301 aaaaaagaaa cagcaggaga tgtttgcaaa cattgcaatc ggcgacagtg ttttgacttc
    15361 aagtggtttt tatggtgtca tcattgatat gaccgatgat acagtgatcg tagaatttgg
    15421 caataataag aactgcagga ttcctatgca gaagactgcg attgtacaag ttgaaaaggc
    15481 acaggcttaa aaaaaacagg gtacccggaa agaggtttac tttttccggg tgcttttttt
    15541 ttgggggggc cgattgtttt taaccgtcac ggtagtggcg gattttttta tatcatagaa
    15601 acgtgtgtct tgtaatttaa aagtcctccg gcgggagatt ctacaaaagc agacttcctg
    15661 ctcttcatac gtaagcgctc cagattctcc cgtcagcatg ggatcttttt tggctatgat
    15721 gaaatgaaat ttcttagaaa aaatatatga taaggcattc acaaagaatt atatataatt
    15781 accacaaaaa gtatgagcca aaaaccagat tttacagtaa taattagcaa taattccgaa
    15841 aagaaatatt attacattat gatattgaca tgaaataaaa attcatttac aattcgagat
    15901 gtaaacacaa accgtattca gcaatgaata cgaatcatgt attggagggc tacatagatg
    15961 aaaatgagca tgtttatgga aaaaagtctg gctgctttgc tggcagcagg tatgacggtc
    16021 agtctgatgg gatgcggagg ccagacaaca gaatctgcac agacagaaac agcgcagcaa
    16081 acgacaactg cgcaagggtc gtcagcagga agcgaaacaa gcggaggaga ggtcacactg
    16141 gaatttcagc aatggtgggg ggtagaatta ccagatggtg tccttaagga aatctgcgat
    16201 ggattcacag aacaatcagg ggtgaaaatc gaattattaa gcaatccgta tgcagatacc
    16261 aagacacaga ttgcagccgg agcggcggca ggaaccatgg cagatgtagt aggtcttgac
    16321 ggatcatggg tttatgattt tgcaaaacag ggttccatta ccaatatgac ggagctgatg
    16381 tcagcagatg gttatgatga cggacaatta tctgatcaga taaaagtaga gggaaaaaca
    16441 tatatgatcc cggtggtcaa ctttgcttat cccatgtatg tcaataaaac gctgttagaa
    16501 tcagcgggta tttcagaaat tcccaagaca tggggggaat ttacggaagc ctgtaaaaaa
    16561 gtttcagcag caaataaagg agctgcaggc tgggccattc ccttatcaac agaatcaccc
    16621 agcgggatcc agaacaattt catgagctgg ttatgggctt caggcggaat catgctaaag
    16681 gatgggaaac cggctttgac agataatccg cttatggcag ataccgttga ttttgtaaaa
    16741 ggtttattcg atgcaggtgt ggttgcaccg ggtgcttatt ccatgaaaga agcagatatg
    16801 gtggaggagt ttacaaacgg ccgcgttgca tttatgacgg attcacttgc ccatttgaca
    16861 acgatcaaga aagaagcgcc tgacttaaaa tttgaattca tgcctgttcc ggtaaaagaa
    16921 ggttatacag gaaagagcgg gatggatgtg gccaactggg gcattgggat tgcagaaaac
    16981 tgcgagcata aagcagaagc catgaagttt gtggaatacc taatgagtcc tgaagtaaat
    17041 gccaggcttg cagtgtatgc aaatgccttc cctggaaata taaatgccaa accagactat
    17101 tccaaagcgg atgagttatt tgtaaaagca tatgaattat accagcagtg ctacgcaatc
    17161 aatgaattta ccgggcttcc cacatcagaa gaattaatga gacagtttga tgagcaatta
    17221 cagttatcca ttgacgggga tacggcttca accgctgata tgctgtccgc aacacaggaa
    17281 atttggcagg gagcattcca ataacaacca gtcaggctgc atgatagaaa agtgcagcct
    17341 gatcttaaaa aggagggaat gagtgagttg gctaaggaaa gagaaacaac gaaaaaggaa
    17401 agcagcggta agacgttaca ggcaatgaaa agaaagcgtg aaccttacct ttatctcctt
    17461 ccaacgattg tgctgatgct tttattgctg attatcccca tctgcatggt ggtccggtat
    17521 tcgttttttg ataatgtaat tgtcaagaaa gatcctgtat ttgccgggct aaagaactat
    17581 gccatgatcc tgtcagacaa aacttttttt gttgcagtga aaaacacctt gttttttgtg
    17641 ggggccagcg taattgttca tatgttttta ggaatgctgt ttgccatact tctcaataca
    17701 aggtatatag gaataaattt gaaagcattt ttccgggtga tttatgtatt gccctggatg
    17761 tttacggcat cagttatcgc catcttatgg aaaatgatga tgaatcccaa tggaattata
    17821 aactacttac tgcaaatcac gaatctcaca tcttcccata tcgaatggct gggttcccgg
    17881 aatttcgcat tattttcagt aacgctgatc aatatatggg ctggatatcc attttatatg
    17941 gtcagcatcc tggcaggact tcaggggata cccacggatc tttatgaggc atcggccatt
    18001 gacggggcca atgcagtaca gcagtttatc cgcattacca ttccccagtt aaagcccatt
    18061 attatcagct tgttcatgct ggattttgtg tggaccatac agcagtttgc cctgatctgg
    18121 atgaccacag gcgggggacc gatcaatgcc acagaaatga taagtacatt tatttataaa
    18181 aggggattca gtaagtatca atattcccag gcctctgcat cggcagtgat cttactggtt
    18241 gtttgttccg tcatagcagt tttttatgtg cggcatcaga gagagaggga ctgattatgg
    18301 taggaaagaa aaagtggtac ataaaactat tgattatgat ccttctggga gccggagcgc
    18361 tgttttcggg gttccccata ttatggatgc tcctcagctc cttgaaaccc aatggggaaa
    18421 tctttgcatg gccgcctata tggatatcag agaatttcag tttgaaagca tatagttcca
    18481 tctttcacaa tcctgaaaag gtgagatttt ttatcaacag ctattgcatt gcaatgcttg
    18541 tggtaatttt gaccctgatt attgggatac ttgcatcgta cagtttcagc cgttttaatt
    18601 ttccgggaaa aagcgttatc aataccctca tcgtcagcgt gcaggcagta cctcccatca
    18661 cccttctgat cccatattta agcctgattg tcagcttgaa attatataat acttttggag
    18721 cgctgatcct tacgtatatg ctgtttacat tgccctatgc cattttgatg attacgggat
    18781 acatgaatac tctgccaaag gatttagatg aagcggtaat gattgacggc ggttccaggt
    18841 ttgtggctct ttggactgtg ctggtcccgg tatcagttcc cggactggtt tccgtgggaa
    18901 tgtatacctt catgcaggca tggaatgaat atttgtttgc attggcattg accaaaacaa
    18961 atgaaatgcg gacggtaccg gtgggcatca gtttactcat ggggcagcat gcgtatgagt
    19021 ggaatcaaat gatgtccatg agcgttttgg gctccttgcc ggtattgatg ctctttttgt
    19081 ttttccagcg gtactttatt gccggaatga cagcaggagc tgtaaaaaat taatacgtat
    19141 gattatccgg aaacggaaat ctaataaaaa agttggagga aaaaactatg ctattaaaca
    19201 tgaaagaact gctggcggct gcaaatgaaa acaattttgc tgtgcctgca tttaacatca
    19261 gctcctatgc gatgttcaat ggaattatgg aggcctcaga agaggaacat gcaccggtta
    19321 ttatttcgat ccatcccgat gaattgagcc atattggaac agatatcatt caggcaatca
    19381 ggcagagggc ttataaaaca aagataccgg tatgcatcca tctggatcat ggctcatcct
    19441 ttgaacagat catgattgcc attcaggcag gatatacctc tgttatgata gacggctcca
    19501 gccttccttt tgaagaaaat attgctgttt gcaaaaaggt atgtgaagcg gcacatgggg
    19561 cagatgtatc ggtagagggc gaactgggca caatcggaac caccgattcc gcagaaacag
    19621 aaaatcaggt gattatttat acaaaaccgg atgatgccgc taaatttgta gaggagacag
    19681 gggttgatac actggcaatc gcgatcggaa cctgccacgg attataccct gccggaatga
    19741 agccggaatt aaagctggat ttattaaaag agatcaaatc caaagtatcc attcccctgg
    19801 tactccatgg aggatccaat aatccggata aagagatcgg ggaatcagta gcattagggg
    19861 tcaataagat caatatttcc agcgatatta aagcggcata ttacatgaaa atgagagagg
    19921 ttttaaaaga cggcagcctt cgggaaccca atatgattga accgccgtgc atagaagcca
    19981 tgaaggaagt ggcatatcac aagatccggc tttttaaggc ggacggaaag gctgcacgtt
    20041 actagggtgt ggctgaagac tgcatgttcc aagatgtgcg ttacactttg taggagattt
    20101 gttccggctg aaggtgcaca gcggattagg ccaaccaaat ttggagcaaa tatgccccaa
    20161 agtgagacgt gcagactgga gcagatcttt ttatgggaaa tggcatatat agcatgagag
    20221 ggcgggcgga tagaatgaag gcagaggaaa aatatattga aacatttgaa caaatagaac
    20281 cattgatcag aagaagaatt gaaaagaatg ctttcacggc actgggttac accagtaatc
    20341 tggatgtatt gtgtgatttt caaatagaag tattcaatga gcttttaagc agatctcttc
    20401 ccaatgggga tctagccgga atgaaagcct caaaagagat cacggatatg gaggggtttt
    20461 tggaaaccat tgtgtatttc tgcacccatg gaatcggcgg agaagttgat atctcggatt
    20521 tcggtataat cagggatacg tttgaagtaa aaaaaggcat gggcgggact gcgacccagg
    20581 gggctatggc tttggcagca gtcacatgcc cttccatcat tcatttgaca gatgattcca
    20641 aagaagtatg cgatatttta aattcaccat atatttatac ggtttccaac aaaggagaat
    20701 taatccatac agatcagatt acacaaacag cagagcagga aatacattat atcattcagt
    20761 ttaaaaaggg agatgtgatt tgccttggca gccagaagat cacaattcca gcctcaaaca
    20821 gactgatcat aaccaaaatt acagtcaatg aagcgcttcc tttctcggat tccttcttca
    20881 cctacgtaga aactcatgcc gcaaatatta agagcaatgt cctttccagc tttaatgcca
    20941 ttcaggataa agggatcttg gaacaaaggc tggcttatgt aaaggaacat atcaaaaaat
    21001 ataaggcaaa caatgaggct ggcatcgtat attttgaaga tgcacattat cataataagg
    21061 aaatccggca ggtatgcctg gagacgcttt atccctatgt tgatattttg agtttaaatg
    21121 aagaagaatt agagtacacc ctcagcatgt atgatttccc catagaaatc aatgatatcc
    21181 attcctgcat aaagggagca gactatatca aagaacggtt ttctgtaaaa aaaggaatca
    21241 ttgtacacac caaggattat tccatgtatc ttggagaaac attaagcggg gatattgaaa
    21301 aaggattaat gctgggcaat atgctggcca ctgcaaaggc ggtcaatggg tggtatggta
    21361 caaaagaaca gatccgtgaa gtcataaagc tgcccttaag tgaaaaagga atgagaaaca
    21421 gggaattgac agcaaaagag cattttccct gggaggtggt tttcgtgccg tcgaaataca
    21481 ttgacaaacc aaggtatacc attggattag gagattcctt tgtagccggc gtgcagctgt
    21541 gttttgaata aaaagcttga aaaagggcgt gatttacggc aatataataa ggtatgaagg
    21601 gagggacatg atgttagaca aacccgtatt ggaagtgatc aaggataatt atgcaaaaat
    21661 attctcagcg gaga
//
