GCF_001518835.1_ASM151883v1_genomic - 4 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP013990.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	arylpolyene	272,087	315,677	aryl polyenes	Other	94%
Region 2	thiopeptide	3,193,431	3,219,733	O-antigen	Saccharide	14%
Region 3	terpene	3,282,286	3,305,855	carotenoid	Terpene	100%
Region 4	NRPS	3,545,076	3,588,942	turnerbactin	NRP	30%

NZ_CP013990.1 - Region 1 - arylpolyene

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Location: 272,087 - 315,677 nt. (total: 43,591 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.53	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.52	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.28	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001723.1	0.24	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000237.1	0.21	Polyketide	lactonamycin Z	Streptomyces sanglieri
BGC0000248.1	0.21	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000272.1	0.21	Polyketide	spore pigment	Streptomyces collinus
BGC0000194.1	0.21	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000261.1	0.20	Polyketide	R1128	Streptomyces sp. R1128
BGC0000219.1	0.20	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.80	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.80	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.62	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001723.1	0.58	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000237.1	0.54	Polyketide	lactonamycin Z	Streptomyces sanglieri
BGC0000248.1	0.54	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000272.1	0.53	Polyketide	spore pigment	Streptomyces collinus
BGC0000194.1	0.53	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000261.1	0.53	Polyketide	R1128	Streptomyces sp. R1128
BGC0000219.1	0.53	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP013990.1 - Region 2 - thiopeptide

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Location: 3,193,431 - 3,219,733 nt. (total: 26,303 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Thiopeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.25	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.16	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.09	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001441.1	0.07	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000981.1	0.07	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0001302.1	0.06	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.05	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.05	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0000957.1	0.04	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0000123.1	0.03	Polyketide	phoslactomycin B	Streptomyces sp. HK803

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.58	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.47	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.34	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001441.1	0.29	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000981.1	0.28	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0001302.1	0.24	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.23	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.22	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0000957.1	0.19	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0000123.1	0.15	Polyketide	phoslactomycin B	Streptomyces sp. HK803

Similar known gene clusters

Thiopeptide predictions

No core peptides found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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Thiopeptides

Core peptide predictions

No core peptides found.

NZ_CP013990.1 - Region 3 - terpene

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Location: 3,282,286 - 3,305,855 nt. (total: 23,570 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000640.1	0.57	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000656.1	0.53	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000647.1	0.48	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000642.1	0.38	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000641.1	0.36	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000639.1	0.36	Terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000638.1	0.36	Terpene	carotenoid	Pantoea ananatis
BGC0000630.1	0.35	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000646.1	0.25	Terpene	β-carotein	uncultured bacterium
BGC0000645.1	0.24	Terpene	carotenoid	Halobacillus halophilus DSM 2266

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000640.1	0.82	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000656.1	0.81	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000647.1	0.77	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000642.1	0.70	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000641.1	0.69	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000639.1	0.69	Terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000638.1	0.69	Terpene	carotenoid	Pantoea ananatis
BGC0000630.1	0.68	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000646.1	0.58	Terpene	β-carotein	uncultured bacterium
BGC0000645.1	0.57	Terpene	carotenoid	Halobacillus halophilus DSM 2266

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP013990.1 - Region 4 - NRPS

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Location: 3,545,076 - 3,588,942 nt. (total: 43,867 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.36	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.33	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.30	NRP	paenibactin	Paenibacillus elgii B69
BGC0001184.1	0.26	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.26	Other	bacilysin	Bacillus sp. CS93
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131.1	0.24	NRP	ambactin	Xenorhabdus miraniensis
BGC0001197.1	0.24	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.23	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.68	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.64	NRP	paenibactin	Paenibacillus elgii B69
BGC0001184.1	0.60	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.60	Other	bacilysin	Bacillus sp. CS93
BGC0001833.1	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131.1	0.57	NRP	ambactin	Xenorhabdus miraniensis
BGC0001197.1	0.57	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001132.1	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.56	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 3545075 - 3588942:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_3272

Search NORINE for peptide: strict or relaxed

AMP-binding (35..433): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: AMPsQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 90% (moderate)

ctg1_3280

Search NORINE for peptide: strict or relaxed

AMP-binding (460..860): ser

NRPSPredictor2: ser

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)