GCF_000146505.1_ASM14650v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NC_017448.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	arylpolyene	281,595	325,281	APE Ec	Other	31%
Region 2	terpene	434,812	455,894
Region 3	NRPS	3,435,751	3,478,720

NC_017448.1 - Region 1 - arylpolyene

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Location: 281,595 - 325,281 nt. (total: 43,687 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001538.1	0.25	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000231.1	0.24	Polyketide	griseusin	Streptomyces griseus
BGC0001444.1	0.23	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000228.1	0.22	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.22	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000837.1	0.22	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000248.1	0.21	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000889.1	0.21	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0000272.1	0.21	Polyketide	spore pigment	Streptomyces collinus
BGC0002008.1	0.20	Other	aryl polyenes	Xenorhabdus doucetiae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001538.1	0.59	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000231.1	0.57	Polyketide	griseusin	Streptomyces griseus
BGC0001444.1	0.56	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0000228.1	0.55	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.55	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000837.1	0.55	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000248.1	0.54	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000889.1	0.54	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0000272.1	0.54	Polyketide	spore pigment	Streptomyces collinus
BGC0002008.1	0.53	Other	aryl polyenes	Xenorhabdus doucetiae

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NC_017448.1 - Region 2 - terpene

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Location: 434,812 - 455,894 nt. (total: 21,083 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001839.1	0.32	Terpene	squalestatin S1	Aspergillus sp. Z5
BGC0000896.1	0.16	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0001104.1	0.08	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0001941.1	0.06	NRP, Polyketide	fulvuthiacene A, fulvuthiacene B	Myxococcus fulvus
BGC0001025.1	0.04	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0001961.1	0.04	NRP	ashimides	Streptomyces sp.
BGC0000385.1	0.03	NRP	lysobactin	Lysobacter sp. ATCC 53042

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001839.1	0.66	Terpene	squalestatin S1	Aspergillus sp. Z5
BGC0000896.1	0.46	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0001104.1	0.31	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0001941.1	0.25	NRP, Polyketide	fulvuthiacene A, fulvuthiacene B	Myxococcus fulvus
BGC0001025.1	0.19	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0001961.1	0.19	NRP	ashimides	Streptomyces sp.
BGC0000385.1	0.16	NRP	lysobactin	Lysobacter sp. ATCC 53042

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NC_017448.1 - Region 3 - NRPS

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Location: 3,435,751 - 3,478,720 nt. (total: 42,970 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000375.1	0.27	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.25	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001561.1	0.23	NRP	curacomycin	Streptomyces curacoi
BGC0001641.1	0.21	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1	0.20	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000342.1	0.20	NRP	enniatin	Fusarium equiseti
BGC0001220.1	0.20	NRP	aculeacin A	Aspergillus japonicus
BGC0001168.1	0.17	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.17	NRP	fragin	Burkholderia cenocepacia H111
BGC0000349.1	0.16	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000375.1	0.61	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.59	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001561.1	0.56	NRP	curacomycin	Streptomyces curacoi
BGC0001641.1	0.53	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1	0.53	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000342.1	0.53	NRP	enniatin	Fusarium equiseti
BGC0001220.1	0.52	NRP	aculeacin A	Aspergillus japonicus
BGC0001168.1	0.48	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.48	NRP	fragin	Burkholderia cenocepacia H111
BGC0000349.1	0.47	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 3435750 - 3478720:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_2843

Search NORINE for peptide: strict or relaxed

AMP-binding (39..394): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vGyFFGiytK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 50% (weak)