LOCUS       c00012_NZ_JHXG..       19911 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHXG01000014.1 Prevotella brevis P6B11
            T496DRAFT_scaffold00012.12_C, whole genome shotgun sequence.
ACCESSION   NZ_JHXG01000014
VERSION     NZ_JHXG01000014
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:57:41
            Original ID  :: NZ_JHXG01000014.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19911
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19911
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9641:9911](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9642..9911
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..19911
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19911
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             739..3024
                     /locus_tag="ctg12_1"
                     /transl_table=11
                     /translation="MRTTIITVAILLGALNSIEAQEKVMSILKTNGSSSKTRVVELDQI
                     KFLPFDINHLQQPSSETQSQPATMIMKLINGAQMRTSVDEVKDISFADTLYHTNSMGQH
                     ILETDELIWPDDRLLPHLLPPASTIKTLDMPAARLGNAERVMFCTLQGIVNRTCPRILL
                     YNHNEEPQSTWPSANGLRTSAISTGNPYELVKSYMEELNGLVLYTNELSDHYANLAVTI
                     GGLDRLLPVTPEVKEKLEANGIQLPVKVDLTQLTMSTATDIYTYLYDNYWQRCNHRLLI
                     SLNPTIPYVHDIGAACGSACVWLDPRIQSERNVLDKMLTDMTPGRDIVLGWYPEERSGV
                     GEATKYGLSTVPADFFENATVYSAVNTPIKIAPVPQRPKLENKIYAAVYISDGDNIQYC
                     QHAMAKIFEQGGRGQMPMNWTISPALADFAPAMLNYYYGKASNNDCFVCGPSGLGYAMP
                     YDAHNNKYYSNYVKTEPFNKYTQLTQRYLEKTGLRIITIWDNIHNRQGNCYANNCSYLY
                     GLTINDWERQNGRLQGSIQSGTLPIAPQYPCYANSTDVVTDFFNRDIKNFDGTKPMFVT
                     GQVTVWDVGPDKLVALKDKLNTLSPGNVSIVRADHWFSYYREANHLPFNITMLQDMKIT
                     CSSAKTPARYAADGSPSSSNTWISRQSKNQGWIQMDFQEPYEISRYVIRHAETSGLDPE
                     LNTRDFTIELSMDGETWTTIGTYTGNTAPVTEANITPTQARYVRLNVTNGGADGYVRIG
                     DIEIEGAH"
     PFAM_domain     1180..1830
                     /aSDomain="GxGYxYP_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16216.7"
                     /description="GxGYxY sequence motif in domain of unknown
                     function N-terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_1_0001"
                     /evalue="7.30E-41"
                     /label="ctg12_1"
                     /locus_tag="ctg12_1"
                     /protein_end="364"
                     /protein_start="147"
                     /score="140.8"
                     /tool="antismash"
                     /translation="CTLQGIVNRTCPRILLYNHNEEPQSTWPSANGLRTSAISTGNPYE
                     LVKSYMEELNGLVLYTNELSDHYANLAVTIGGLDRLLPVTPEVKEKLEANGIQLPVKVD
                     LTQLTMSTATDIYTYLYDNYWQRCNHRLLISLNPTIPYVHDIGAACGSACVWLDPRIQS
                     ERNVLDKMLTDMTPGRDIVLGWYPEERSGVGEATKYGLSTVPADFFENATVYSA"
     PFAM_domain     1882..2589
                     /aSDomain="GxGYxYP_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14323.8"
                     /description="GxGYxYP putative glycoside hydrolase
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_1_0002"
                     /evalue="2.70E-49"
                     /label="ctg12_1"
                     /locus_tag="ctg12_1"
                     /protein_end="617"
                     /protein_start="381"
                     /score="168.4"
                     /tool="antismash"
                     /translation="NKIYAAVYISDGDNIQYCQHAMAKIFEQGGRGQMPMNWTISPALA
                     DFAPAMLNYYYGKASNNDCFVCGPSGLGYAMPYDAHNNKYYSNYVKTEPFNKYTQLTQR
                     YLEKTGLRIITIWDNIHNRQGNCYANNCSYLYGLTINDWERQNGRLQGSIQSGTLPIAP
                     QYPCYANSTDVVTDFFNRDIKNFDGTKPMFVTGQVTVWDVGPDKLVALKDKLNTLSPGN
                     VSIVRADHWFSYYR"
     PFAM_domain     2638..2976
                     /aSDomain="F5_F8_type_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00754.27"
                     /description="F5/8 type C domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_1_0003"
                     /evalue="4.20E-20"
                     /label="ctg12_1"
                     /locus_tag="ctg12_1"
                     /protein_end="746"
                     /protein_start="633"
                     /score="72.3"
                     /tool="antismash"
                     /translation="ITCSSAKTPARYAADGSPSSSNTWISRQSKNQGWIQMDFQEPYEI
                     SRYVIRHAETSGLDPELNTRDFTIELSMDGETWTTIGTYTGNTAPVTEANITPTQARYV
                     RLNVTNGGA"
     CDS             complement(3398..4666)
                     /locus_tag="ctg12_2"
                     /transl_table=11
                     /translation="MKSKVRNLQQLPVYKIAYLAIRFFTKERVVNQASALTYSTLLAIV
                     PIMAVIFAIARGFGYNRYIELWFRDAFSSQPQVAEVIIGFVNSYLVHTKSGIFLGVGLI
                     FMLYTVMLLVNHIEIAFNEIWQVKRKRSIFRTVTDYFAMFFLFPIFIVISTGLSLFLAT
                     MADSMTDFLLLGSFVRKLIDMSPYILMSLLFIGLYVFMPNTHVKVKNAIIPGILSGIAM
                     QLVQFFYIHSQMWVTGYNAIYGSFAALPMFMLWVQISWTICLFGAELTYTSQNLDYYVY
                     NGRTEDISHRYQLMLSALLMSIVCRRFAAGRRGPTAEELRQSSGIPIRVVYDLLYQLQE
                     ARLLIEITPDEKGDESRYLPAESLDNLSVGVMVDRLEAQGRWQLNLPVANLLTDEWVRA
                     VVQRNAYLRQARDIRLESLYKGE"
     PFAM_domain     complement(3842..4588)
                     /aSDomain="Virul_fac_BrkB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03631.17"
                     /description="Virulence factor BrkB"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_2_0004"
                     /evalue="1.70E-47"
                     /label="ctg12_2"
                     /locus_tag="ctg12_2"
                     /protein_end="275"
                     /protein_start="26"
                     /score="162.3"
                     /tool="antismash"
                     /translation="ERVVNQASALTYSTLLAIVPIMAVIFAIARGFGYNRYIELWFRDA
                     FSSQPQVAEVIIGFVNSYLVHTKSGIFLGVGLIFMLYTVMLLVNHIEIAFNEIWQVKRK
                     RSIFRTVTDYFAMFFLFPIFIVISTGLSLFLATMADSMTDFLLLGSFVRKLIDMSPYIL
                     MSLLFIGLYVFMPNTHVKVKNAIIPGILSGIAMQLVQFFYIHSQMWVTGYNAIYGSFAA
                     LPMFMLWVQISWTICLFGAELTYTSQN"
     aSDomain        complement(3851..4606)
                     /aSDomain="TIGR00765"
                     /aSTool="tigrfam"
                     /description="yihY_not_rbn: YihY family inner membrane
                     protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_2_0001"
                     /evalue="5.90E-42"
                     /identifier="TIGR00765"
                     /label="ctg12_2"
                     /locus_tag="ctg12_2"
                     /protein_end="272"
                     /protein_start="20"
                     /score="142.2"
                     /tool="antismash"
                     /translation="IRFFTKERVVNQASALTYSTLLAIVPIMAVIFAIARGFGYNRYIE
                     LWFRDAFSSQPQVAEVIIGFVNSYLVHTKSGIFLGVGLIFMLYTVMLLVNHIEIAFNEI
                     WQVKRKRSIFRTVTDYFAMFFLFPIFIVISTGLSLFLATMADSMTDFLLLGSFVRKLID
                     MSPYILMSLLFIGLYVFMPNTHVKVKNAIIPGILSGIAMQLVQFFYIHSQMWVTGYNAI
                     YGSFAALPMFMLWVQISWTICLFGAELTYT"
     CDS             5311..6828
                     /locus_tag="ctg12_3"
                     /transl_table=11
                     /translation="MKIMDKKKIANYVIPALSLTAIVFSVAAFNQTNAANVLAANPETT
                     EISNLPAAQPVDLTYAAEKALPTVVHIKYVQNSKIQTVEVQSDPFEDFFSDPFGGFFGR
                     GQRGQGGTRKQKVQTPKKTATGSGVIISTDGYIVTNNHVVDGADELTVTLSDSKEYSAR
                     IIGADKTTDLALIKIDGKNLPAIRIANSDNVKVGEWVLAIGNPLGLNNTVTAGIISAKA
                     RTLGANGVESFIQTDAAINAGNSGGALVNTNGELVGINAMLYSQTGSYSGYGFAIPTAM
                     MNKVVEDLKKYGTVQRAMIGIGGHDVKAQVDLEKEEGKEPTDYGTMEGVYVGEVLEESA
                     AAEAGIEKGDIIIEVDGKKLTKYGELSGILAQKRPGDKVTLTYLHNKKKQTKTVTLRNE
                     QGNTKVVKNADMDVLGADFREITKAQKEQLEISYGLEVLKVNAGKMKEAGIPKGFIIQR
                     VNDEQIKSVEDLQEVVKEASTSKEPVLIIKGLFPTGKRGYFVVQLSE"
     aSDomain        5485..6771
                     /aSDomain="TIGR02037"
                     /aSTool="tigrfam"
                     /description="degP_htrA_DO: peptidase Do"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_3_0002"
                     /evalue="3.20E-127"
                     /identifier="TIGR02037"
                     /label="ctg12_3"
                     /locus_tag="ctg12_3"
                     /protein_end="487"
                     /protein_start="58"
                     /score="423.0"
                     /tool="antismash"
                     /translation="TYAAEKALPTVVHIKYVQNSKIQTVEVQSDPFEDFFSDPFGGFFG
                     RGQRGQGGTRKQKVQTPKKTATGSGVIISTDGYIVTNNHVVDGADELTVTLSDSKEYSA
                     RIIGADKTTDLALIKIDGKNLPAIRIANSDNVKVGEWVLAIGNPLGLNNTVTAGIISAK
                     ARTLGANGVESFIQTDAAINAGNSGGALVNTNGELVGINAMLYSQTGSYSGYGFAIPTA
                     MMNKVVEDLKKYGTVQRAMIGIGGHDVKAQVDLEKEEGKEPTDYGTMEGVYVGEVLEES
                     AAAEAGIEKGDIIIEVDGKKLTKYGELSGILAQKRPGDKVTLTYLHNKKKQTKTVTLRN
                     EQGNTKVVKNADMDVLGADFREITKAQKEQLEISYGLEVLKVNAGKMKEAGIPKGFIIQ
                     RVNDEQIKSVEDLQEVVKEASTSKEPVLII"
     PFAM_domain     5686..6087
                     /aSDomain="Trypsin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13365.8"
                     /description="Trypsin-like peptidase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_3_0005"
                     /evalue="3.90E-33"
                     /label="ctg12_3"
                     /locus_tag="ctg12_3"
                     /protein_end="259"
                     /protein_start="125"
                     /score="115.6"
                     /tool="antismash"
                     /translation="GSGVIISTDGYIVTNNHVVDGADELTVTLSDSKEYSARIIGADKT
                     TDLALIKIDGKNLPAIRIANSDNVKVGEWVLAIGNPLGLNNTVTAGIISAKARTLGANG
                     VESFIQTDAAINAGNSGGALVNTNGELVGI"
     PFAM_domain     6262..6498
                     /aSDomain="PDZ_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13180.8"
                     /description="PDZ domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_3_0006"
                     /evalue="5.60E-16"
                     /label="ctg12_3"
                     /locus_tag="ctg12_3"
                     /protein_end="396"
                     /protein_start="317"
                     /score="58.8"
                     /tool="antismash"
                     /translation="GKEPTDYGTMEGVYVGEVLEESAAAEAGIEKGDIIIEVDGKKLTK
                     YGELSGILAQKRPGDKVTLTYLHNKKKQTKTVTL"
     CDS             6942..7805
                     /locus_tag="ctg12_4"
                     /transl_table=11
                     /translation="MRQLKITKSITNRESEALDKYLQEIGKESMISTEEEVELAQLIRK
                     GDRKALEKLTKANLRFVVSVAKQYQNQGLSLPDLINEGNLGLIKAAEKFDETRGFKFIS
                     YAVWWIRQSILQAIAEQSRIVRLPLNQVGSMNKINRVASKFEQENERRPSARELSEHID
                     LPMEKIDEAINISGKQVSVDAPFADGEESSLLDVLVNDNSPSADRELVRESLQSEIRDV
                     LKELSERERNIIMAFFGIDQPEMTLEEIGVRFGLTRERVRQIKEKAIRRLRCNAKNKVL
                     LSYLGA"
     PFAM_domain     6990..7085
                     /aSDomain="Sigma70_r1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00140.22"
                     /description="Sigma-70 factor, region 1.2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_4_0007"
                     /evalue="3.80E-10"
                     /label="ctg12_4"
                     /locus_tag="ctg12_4"
                     /protein_end="48"
                     /protein_start="16"
                     /score="39.7"
                     /tool="antismash"
                     /translation="ALDKYLQEIGKESMISTEEEVELAQLIRKGDR"
     aSDomain        7089..7760
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_4_0003"
                     /evalue="2.40E-34"
                     /identifier="TIGR02937"
                     /label="ctg12_4"
                     /locus_tag="ctg12_4"
                     /protein_end="273"
                     /protein_start="49"
                     /score="116.3"
                     /tool="antismash"
                     /translation="ALEKLTKANLRFVVSVAKQYQNQGLSLPDLINEGNLGLIKAAEKF
                     DETRGFKFISYAVWWIRQSILQAIAEQSRIVRLPLNQVGSMNKINRVASKFEQENERRP
                     SARELSEHIDLPMEKIDEAINISGKQVSVDAPFADGEESSLLDVLVNDNSPSADRELVR
                     ESLQSEIRDVLKELSERERNIIMAFFGIDQPEMTLEEIGVRFGLTRERVRQIKEKAIRR
                     LR"
     PFAM_domain     7107..7310
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_4_0008"
                     /evalue="1.20E-17"
                     /label="ctg12_4"
                     /locus_tag="ctg12_4"
                     /protein_end="123"
                     /protein_start="55"
                     /score="63.5"
                     /tool="antismash"
                     /translation="KANLRFVVSVAKQYQNQGLSLPDLINEGNLGLIKAAEKFDETRGF
                     KFISYAVWWIRQSILQAIAEQSR"
     PFAM_domain     7344..7562
                     /aSDomain="Sigma70_r3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04539.18"
                     /description="Sigma-70 region 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_4_0009"
                     /evalue="3.70E-14"
                     /label="ctg12_4"
                     /locus_tag="ctg12_4"
                     /protein_end="207"
                     /protein_start="134"
                     /score="52.7"
                     /tool="antismash"
                     /translation="MNKINRVASKFEQENERRPSARELSEHIDLPMEKIDEAINISGKQ
                     VSVDAPFADGEESSLLDVLVNDNSPSAD"
     PFAM_domain     7605..7760
                     /aSDomain="Sigma70_r4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04545.18"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_4_0010"
                     /evalue="2.70E-16"
                     /label="ctg12_4"
                     /locus_tag="ctg12_4"
                     /protein_end="273"
                     /protein_start="221"
                     /score="58.9"
                     /tool="antismash"
                     /translation="VLKELSERERNIIMAFFGIDQPEMTLEEIGVRFGLTRERVRQIKE
                     KAIRRLR"
     CDS             7874..8278
                     /locus_tag="ctg12_5"
                     /transl_table=11
                     /translation="MLAALFGTATTVKAKKVVVPKMYVFGVAASFNDTIVHFTDIQEVD
                     SAWIDKKTKFLAGRDNYSYQLRDYLEQQQMPHRTCIVFYNKQRSKLEKKYLKMKRLYMP
                     GKDGKVHFDLRHLKSGDFKFMAYDASEDEK"
     CDS             8268..9149
                     /locus_tag="ctg12_6"
                     /transl_table=11
                     /translation="MRNSHYFTIAEHNICINFTDGQKNAMELLPSFCQFSTNAPQEELL
                     FTLTIDDTLSPRKDKTLVRKFDTGNGDTIVYQLSDGGYQYVIRDTHGRDCCLLISNRTF
                     NECQCALNGDWTMRSFGLNDALMLIYAFAGAYHHTMLIHASCIKYGAWGFPFTAKSGTG
                     KSTHTALWMKYIDGAELLNDDNPIIRIINNKAYIYGSPWSGKTPCYRNVKTQLAAITTI
                     CRAPENSIQKLGPVQAFASLLPACSSMMWDSDIHNFLCDDLTQLIEKTPIYTLHCLPNE
                     EAAQLCYKTIVP"
     CDS             9161..9616
                     /locus_tag="ctg12_7"
                     /transl_table=11
                     /translation="MDNDQFLPQVVNLLQEGHTVTLPLRGRSMRPFLEDGRDKALLKIA
                     KHYAVGDAVLAEIAKGSFVLHRIIAIDGDDVTLRGDGNLNNEYCKIIDIRAKAIGFYRK
                     GRNKLDSTDGCKWRIYSWWWTRLYSIRRYLLFAMHPHIPRRWRRQTS"
     CDS             9642..9911
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_8"
                     /sec_met_domain="PF05402 (E-value: 2.9e-16, bitscore: 51.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.5e-09,
                     bitscore: 29.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKKGFRLRNICGENVIVAEGIENIDFSRIISMNESAAYLWNKV
                     QSIDFTANTLIDLLLEEYEVSREDAAQDVNQLIEQWQKAGIVED"
     PFAM_domain     9690..9902
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_8_0011"
                     /evalue="1.40E-13"
                     /label="ctg12_8"
                     /locus_tag="ctg12_8"
                     /protein_end="87"
                     /protein_start="16"
                     /score="51.0"
                     /tool="antismash"
                     /translation="VIVAEGIENIDFSRIISMNESAAYLWNKVQSIDFTANTLIDLLLE
                     EYEVSREDAAQDVNQLIEQWQKAGIV"
     CDS             complement(9908..10738)
                     /locus_tag="ctg12_9"
                     /transl_table=11
                     /translation="MIIFPIAKINLGLNVVERRTDGYHNLETVFFPVALKDALEVTVMD
                     EAFPSDYDCDLKVSNIAIEGDEQKNLVVKAYNLLKQDFPQMPRVHAHLYKAIPTQAGMG
                     GGSSDCAAMLVLLNRMFELGLTEQQLIGYAARLGADCAFFVLNTPSYAEGIGEQLMPID
                     LSLDDYWLAVVRPDIPVPTKEAFSLITPARPEKNCRDVVQQPISSWRHDLKNDFEKSVF
                     ALHPEIGAIKQRLYDMGAEYAAMSGSGSAVFGIFSHEPSLESEFDGMFKQILKL"
     PFAM_domain     complement(9950..10102)
                     /aSDomain="GHMP_kinases_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08544.15"
                     /description="GHMP kinases C terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_9_0013"
                     /evalue="1.00E-06"
                     /label="ctg12_9"
                     /locus_tag="ctg12_9"
                     /protein_end="263"
                     /protein_start="212"
                     /score="29.1"
                     /tool="antismash"
                     /translation="LKNDFEKSVFALHPEIGAIKQRLYDMGAEYAAMSGSGSAVFGIFS
                     HEPSLE"
     aSDomain        complement(9956..10720)
                     /aSDomain="TIGR00154"
                     /aSTool="tigrfam"
                     /description="ispE: 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_9_0004"
                     /evalue="5.70E-54"
                     /identifier="TIGR00154"
                     /label="ctg12_9"
                     /locus_tag="ctg12_9"
                     /protein_end="261"
                     /protein_start="6"
                     /score="181.6"
                     /tool="antismash"
                     /translation="AKINLGLNVVERRTDGYHNLETVFFPVALKDALEVTVMDEAFPSD
                     YDCDLKVSNIAIEGDEQKNLVVKAYNLLKQDFPQMPRVHAHLYKAIPTQAGMGGGSSDC
                     AAMLVLLNRMFELGLTEQQLIGYAARLGADCAFFVLNTPSYAEGIGEQLMPIDLSLDDY
                     WLAVVRPDIPVPTKEAFSLITPARPEKNCRDVVQQPISSWRHDLKNDFEKSVFALHPEI
                     GAIKQRLYDMGAEYAAMSGSGSAVFGIFSHEPS"
     PFAM_domain     complement(10301..10471)
                     /aSDomain="GHMP_kinases_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00288.28"
                     /description="GHMP kinases N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_9_0012"
                     /evalue="2.00E-07"
                     /label="ctg12_9"
                     /locus_tag="ctg12_9"
                     /protein_end="146"
                     /protein_start="89"
                     /score="31.2"
                     /tool="antismash"
                     /translation="HAHLYKAIPTQAGMGGGSSDCAAMLVLLNRMFELGLTEQQLIGYA
                     ARLGADCAFFVL"
     CDS             10840..12381
                     /locus_tag="ctg12_10"
                     /transl_table=11
                     /translation="MPEQNTTKRRSRKQQPVDNTYAHLQPQALDIERAVLGALLIDKDA
                     YSVVCEMLFPESFYDPRHQMIYTAIRDLAMAEKPVDVLTVTEQMAKNGQLEEAGGPSYI
                     AEISTRIASSAHVDYHARIVAQKFLARQLIQFAGDIETKAFDETIDVDELMQQAEGALF
                     ELSQKNMKKDYTQIDPVVGQAMQAIQKAAGNSGGLTGVPTGYHKLDDMTSGWQASDLVI
                     IAGRPAMGKTSFALSMAKNIAADYQVPMAFFSLEMSNVQLVNRLISNCCEIQGSKILNG
                     QLQPDEWDRLDKRINGLLGAPLYVDDTPGLSVFELRTKARRLVREHGVKIIMIDYLQLM
                     NANGMRFSSRQEEVSTISRSLKGLAKELDVPILALSQLNRGVESREGLEGKRPQLSDLR
                     ESGAIEQDADMVLFVHRPEYYHIFQDDNGRDLHGMAQIIIAKHRKGATGDVLLTFRGEY
                     TRFENPEDTRLENRAPQDGGGEILGSRVNGENNIPDNFDPFGGSPLPPPPGDAPF"
     PFAM_domain     10912..11214
                     /aSDomain="DnaB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00772.23"
                     /description="DnaB-like helicase N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_10_0014"
                     /evalue="7.40E-31"
                     /label="ctg12_10"
                     /locus_tag="ctg12_10"
                     /protein_end="125"
                     /protein_start="24"
                     /score="106.4"
                     /tool="antismash"
                     /translation="QPQALDIERAVLGALLIDKDAYSVVCEMLFPESFYDPRHQMIYTA
                     IRDLAMAEKPVDVLTVTEQMAKNGQLEEAGGPSYIAEISTRIASSAHVDYHARIVA"
     aSDomain        10912..12231
                     /aSDomain="TIGR00665"
                     /aSTool="tigrfam"
                     /description="DnaB: replicative DNA helicase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_10_0005"
                     /evalue="3.80E-160"
                     /identifier="TIGR00665"
                     /label="ctg12_10"
                     /locus_tag="ctg12_10"
                     /protein_end="464"
                     /protein_start="24"
                     /score="531.4"
                     /tool="antismash"
                     /translation="QPQALDIERAVLGALLIDKDAYSVVCEMLFPESFYDPRHQMIYTA
                     IRDLAMAEKPVDVLTVTEQMAKNGQLEEAGGPSYIAEISTRIASSAHVDYHARIVAQKF
                     LARQLIQFAGDIETKAFDETIDVDELMQQAEGALFELSQKNMKKDYTQIDPVVGQAMQA
                     IQKAAGNSGGLTGVPTGYHKLDDMTSGWQASDLVIIAGRPAMGKTSFALSMAKNIAADY
                     QVPMAFFSLEMSNVQLVNRLISNCCEIQGSKILNGQLQPDEWDRLDKRINGLLGAPLYV
                     DDTPGLSVFELRTKARRLVREHGVKIIMIDYLQLMNANGMRFSSRQEEVSTISRSLKGL
                     AKELDVPILALSQLNRGVESREGLEGKRPQLSDLRESGAIEQDADMVLFVHRPEYYHIF
                     QDDNGRDLHGMAQIIIAKHRKGATGDVLLTFRGEYTRFENP"
     PFAM_domain     11437..12228
                     /aSDomain="DnaB_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03796.17"
                     /description="DnaB-like helicase C terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_10_0015"
                     /evalue="9.80E-106"
                     /label="ctg12_10"
                     /locus_tag="ctg12_10"
                     /protein_end="463"
                     /protein_start="199"
                     /score="352.8"
                     /tool="antismash"
                     /translation="GVPTGYHKLDDMTSGWQASDLVIIAGRPAMGKTSFALSMAKNIAA
                     DYQVPMAFFSLEMSNVQLVNRLISNCCEIQGSKILNGQLQPDEWDRLDKRINGLLGAPL
                     YVDDTPGLSVFELRTKARRLVREHGVKIIMIDYLQLMNANGMRFSSRQEEVSTISRSLK
                     GLAKELDVPILALSQLNRGVESREGLEGKRPQLSDLRESGAIEQDADMVLFVHRPEYYH
                     IFQDDNGRDLHGMAQIIIAKHRKGATGDVLLTFRGEYTRFEN"
     CDS             complement(12393..13499)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_11"
                     /sec_met_domain="PF04055 (E-value: 1.2e-22, bitscore: 73.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGLYIHIPFCASRCVYCGFFSTTQLDLSQRYVDALCKEMQCRQS
                     QQIISTIYLGGGTPSQLSSQQLKQLFSYIYKVYRVDPLAEVTMECNPDDVTQQFIESLS
                     ELPVNRVSMGVQTFNNDRLRFLRRRHNADQIAPSVELLRRAGVSNISIDLMYGFPQQTL
                     SEWLLDINKALSLDVEHLSAYALQYEEGTALYRMLEKGEVNEIDEELERQMYFELIDRL
                     ASAGYEHYEISNFARIGCRSRHNSSYWNQTPYIGLGAAAHSYDGFKRQWNVSSLSEYLE
                     GIESGLQHVDFEELDESTRYNDLVMTALRTCDGLSLQLLTPQQRQYCLSMSQKYLSNGW
                     LKLVDNHLILTREGLFVSDMIMAELMKV"
     aSDomain        complement(12504..13490)
                     /aSDomain="TIGR00539"
                     /aSTool="tigrfam"
                     /description="hemN_rel: putative oxygen-independent
                     coproporphyrinogen III oxidase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_11_0006"
                     /evalue="7.20E-89"
                     /identifier="TIGR00539"
                     /label="ctg12_11"
                     /locus_tag="ctg12_11"
                     /protein_end="332"
                     /protein_start="3"
                     /score="296.3"
                     /tool="antismash"
                     /translation="LYIHIPFCASRCVYCGFFSTTQLDLSQRYVDALCKEMQCRQSQQI
                     ISTIYLGGGTPSQLSSQQLKQLFSYIYKVYRVDPLAEVTMECNPDDVTQQFIESLSELP
                     VNRVSMGVQTFNNDRLRFLRRRHNADQIAPSVELLRRAGVSNISIDLMYGFPQQTLSEW
                     LLDINKALSLDVEHLSAYALQYEEGTALYRMLEKGEVNEIDEELERQMYFELIDRLASA
                     GYEHYEISNFARIGCRSRHNSSYWNQTPYIGLGAAAHSYDGFKRQWNVSSLSEYLEGIE
                     SGLQHVDFEELDESTRYNDLVMTALRTCDGLSLQLLTPQQRQYCLSMS"
     PFAM_domain     complement(13002..13484)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_11_0016"
                     /evalue="5.50E-20"
                     /label="ctg12_11"
                     /locus_tag="ctg12_11"
                     /protein_end="166"
                     /protein_start="5"
                     /score="72.5"
                     /tool="antismash"
                     /translation="IHIPFCASRCVYCGFFSTTQLDLSQRYVDALCKEMQCRQSQQIIS
                     TIYLGGGTPSQLSSQQLKQLFSYIYKVYRVDPLAEVTMECNPDDVTQQFIESLSELPVN
                     RVSMGVQTFNNDRLRFLRRRHNADQIAPSVELLRRAGVSNISIDLMYGFPQQTLSEW"
     CDS             13645..15804
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 68.1; E-value:
                     1.1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_12"
                     /transl_table=11
                     /translation="MKVYQTNEIKNIALLGSAGSGKTTLAEAMVYEAGIIKRRGTVEGK
                     NTMSDYFPVEQEYGYSVFSTVFHVEWNNKKLNIIDCPGSDDFVGGAITALNVTDQAVIL
                     INGQYGPEVGTQNAFRYTDKLQKPVIFLVNQLDKEHCDFDTILNNMKEIYGEKCVPVQY
                     PISTGPDFNAVIDVLLMKKYSWKPEGGAPIIEDIPADQMEKAKELHAALVEAAAANDDT
                     LMEKFFESESLTEDEMREGIRKGLVTRSIFPVFCVCAGKDMGVRRLMEFLGNVVPFVSE
                     MPKVRNTRGEEVTPDAAGPASLYFFKTGVEPHIGEVQYFKVMSGSVKSGDDLTNADRGS
                     KERIGTIYACAGANRIPVDELKAGDIGCTVKLKDVKTGNALNGKDCEWRYDFIKYPNSK
                     YSRAIKAVNEAETEKMMVALTKMRQEDPTWVVEQSKELRQIIVHGQGEFHLRTLKWRME
                     NNEKIKIEYLEPKIPYRETITKMARADYRHKKQSGGAGQFGEVHLIVEPYADGMPDPTS
                     FKINGQEFKMNIKGKEEIDLEWGGKLVFINSVVGGAIDMRFMPAILKGVMERMEQGPLT
                     GSYARDVRVIVYDGKMHPVDSNELSFMLAARNAFSAAFREAGPKVLEPIYDLEVYVPSD
                     YMGDVMSDLQGRRAIIMGMDSEAGYQKLSAKIPLKELSNYSIALSSITGGRASFTTKFA
                     SYELVPNDIQQQLIKEHEAELKDED"
     PFAM_domain     13666..14472
                     /aSDomain="GTP_EFTU"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00009.29"
                     /description="Elongation factor Tu GTP binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_12_0017"
                     /evalue="1.80E-34"
                     /label="ctg12_12"
                     /locus_tag="ctg12_12"
                     /protein_end="276"
                     /protein_start="7"
                     /score="119.1"
                     /tool="antismash"
                     /translation="EIKNIALLGSAGSGKTTLAEAMVYEAGIIKRRGTVEGKNTMSDYF
                     PVEQEYGYSVFSTVFHVEWNNKKLNIIDCPGSDDFVGGAITALNVTDQAVILINGQYGP
                     EVGTQNAFRYTDKLQKPVIFLVNQLDKEHCDFDTILNNMKEIYGEKCVPVQYPISTGPD
                     FNAVIDVLLMKKYSWKPEGGAPIIEDIPADQMEKAKELHAALVEAAAANDDTLMEKFFE
                     SESLTEDEMREGIRKGLVTRSIFPVFCVCAGKDMGVRRLMEFLGNVV"
     aSDomain        13669..14166
                     /aSDomain="TIGR00231"
                     /aSTool="tigrfam"
                     /description="small_GTP: small GTP-binding protein domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_12_0007"
                     /evalue="1.20E-13"
                     /identifier="TIGR00231"
                     /label="ctg12_12"
                     /locus_tag="ctg12_12"
                     /protein_end="174"
                     /protein_start="8"
                     /score="49.2"
                     /tool="antismash"
                     /translation="IKNIALLGSAGSGKTTLAEAMVYEAGIIKRRGTVEGKNTMSDYFP
                     VEQEYGYSVFSTVFHVEWNNKKLNIIDCPGSDDFVGGAITALNVTDQAVILINGQYGPE
                     VGTQNAFRYTDKLQKPVIFLVNQLDKEHCDFDTILNNMKEIYGEKCVPVQYPISTGPDF
                     NAV"
     PFAM_domain     14830..15042
                     /aSDomain="EFG_III"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14492.8"
                     /description="Elongation Factor G, domain III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_12_0018"
                     /evalue="7.40E-13"
                     /label="ctg12_12"
                     /locus_tag="ctg12_12"
                     /protein_end="466"
                     /protein_start="395"
                     /score="48.5"
                     /tool="antismash"
                     /translation="PNSKYSRAIKAVNEAETEKMMVALTKMRQEDPTWVVEQSKELRQI
                     IVHGQGEFHLRTLKWRMENNEKIKIE"
     PFAM_domain     15052..15171
                     /aSDomain="EFG_IV"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03764.20"
                     /description="Elongation factor G, domain IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_12_0019"
                     /evalue="2.00E-07"
                     /label="ctg12_12"
                     /locus_tag="ctg12_12"
                     /protein_end="509"
                     /protein_start="469"
                     /score="30.9"
                     /tool="antismash"
                     /translation="PKIPYRETITKMARADYRHKKQSGGAGQFGEVHLIVEPYA"
     PFAM_domain     15256..15495
                     /aSDomain="EFG_IV"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03764.20"
                     /description="Elongation factor G, domain IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_12_0020"
                     /evalue="2.40E-20"
                     /label="ctg12_12"
                     /locus_tag="ctg12_12"
                     /protein_end="617"
                     /protein_start="537"
                     /score="72.6"
                     /tool="antismash"
                     /translation="EWGGKLVFINSVVGGAIDMRFMPAILKGVMERMEQGPLTGSYARD
                     VRVIVYDGKMHPVDSNELSFMLAARNAFSAAFREA"
     PFAM_domain     15505..15762
                     /aSDomain="EFG_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00679.26"
                     /description="Elongation factor G C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_12_0021"
                     /evalue="6.10E-26"
                     /label="ctg12_12"
                     /locus_tag="ctg12_12"
                     /protein_end="706"
                     /protein_start="620"
                     /score="90.4"
                     /tool="antismash"
                     /translation="VLEPIYDLEVYVPSDYMGDVMSDLQGRRAIIMGMDSEAGYQKLSA
                     KIPLKELSNYSIALSSITGGRASFTTKFASYELVPNDIQQQ"
     CDS             16028..17596
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 168.9; E-value: 3.9e-51)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg12_13"
                     /transl_table=11
                     /translation="MKKSTIWIIAAVMGTSFLGLLYLQISYIEEMAKMKKEQFDESVTR
                     SLYQASRNLELNETLRYLEKDVNEVERKAFTQDSVIVNSLDGSIQHAHQFSVSADDGTF
                     YSAFELKTFTTKPASVPKAMIMHSDKNQKSEAAKTLQEIVRNRYVYQKALLDEVVYNIL
                     YTASEKPLKERVNFKLLDQDIRSELMNNGISIPYHFTVSTADGREIYRCPDYSDEGDEY
                     TYTQTLYRNDPSSRMGVVKIHFPDMSSYIFSSIRFMIPALIFTMVLLLTFIFTIVVIFR
                     QKRYTEIKNDFINNMTHELKTPISSISLAAQMMNDDSVTKSQSMMKHLSGVINDESKRL
                     RFLVEKVLQMSMFDRKTASFKKKELDLNELLEQTASSFNLRVEHTGGNITTEIEAIDSA
                     IYVDEVHFQNAITNLMDNAVKYRKPDEPINIHIRTWNEGTNLLCFSIEDNGLGIKKDNV
                     KKVFDKFYRVHTGNVHDVKGFGLGLAYVKKIINLHDGEIKCESEIGKGTKFTVKLPVLK
                     EDSTQ"
     PFAM_domain     16892..17089
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_13_0022"
                     /evalue="1.60E-11"
                     /label="ctg12_13"
                     /locus_tag="ctg12_13"
                     /protein_end="354"
                     /protein_start="288"
                     /score="44.1"
                     /tool="antismash"
                     /translation="KNDFINNMTHELKTPISSISLAAQMMNDDSVTKSQSMMKHLSGVI
                     NDESKRLRFLVEKVLQMSMFD"
     PFAM_domain     17234..17572
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_13_0023"
                     /evalue="2.00E-24"
                     /label="ctg12_13"
                     /locus_tag="ctg12_13"
                     /protein_end="515"
                     /protein_start="402"
                     /score="86.3"
                     /tool="antismash"
                     /translation="DEVHFQNAITNLMDNAVKYRKPDEPINIHIRTWNEGTNLLCFSIE
                     DNGLGIKKDNVKKVFDKFYRVHTGNVHDVKGFGLGLAYVKKIINLHDGEIKCESEIGKG
                     TKFTVKLPV"
     CDS             17706..18404
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 173.7; E-value: 6.8e-53)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg12_14"
                     /transl_table=11
                     /translation="MEDKLKILLCEDDENLGMLLREYLAAKGFEAELCPDGDAGFKAFM
                     KTKFDICVLDVMMPKKDGFTLAQEIRSANADMPIIFLTAKTLKEDILEGFKLGADDYIT
                     KPFSMEELVFRIEAILRRVHGKKTKESTLYHIGNFIFDTQKQLLTMGDKQTKLTTKENE
                     LLALLCSHANEILQRDFALKTIWIDDNYFNARSMDVYITKLRKHLKDDPQIEIINIHGK
                     GYKLITPEEQ"
     PFAM_domain     17724..18053
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_14_0024"
                     /evalue="5.40E-27"
                     /label="ctg12_14"
                     /locus_tag="ctg12_14"
                     /protein_end="116"
                     /protein_start="6"
                     /score="94.3"
                     /tool="antismash"
                     /translation="ILLCEDDENLGMLLREYLAAKGFEAELCPDGDAGFKAFMKTKFDI
                     CVLDVMMPKKDGFTLAQEIRSANADMPIIFLTAKTLKEDILEGFKLGADDYITKPFSME
                     ELVFRI"
     PFAM_domain     18162..18383
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_14_0025"
                     /evalue="2.30E-18"
                     /label="ctg12_14"
                     /locus_tag="ctg12_14"
                     /protein_end="226"
                     /protein_start="152"
                     /score="66.2"
                     /tool="antismash"
                     /translation="KQTKLTTKENELLALLCSHANEILQRDFALKTIWIDDNYFNARSM
                     DVYITKLRKHLKDDPQIEIINIHGKGYKL"
     CDS             18445..18570
                     /locus_tag="ctg12_15"
                     /transl_table=11
                     /translation="MKEKTSPPFLFYLFKPKICLYRKNLVFLRAETILNTEKKKI"
ORIGIN
        1 gaggtttggc ctgcttcgca gggaaatttt tcaaaattga aaacaaaatt tttcattttt
       61 attttctttc tcgcctgaca caagccgaag ggatataaat ctctttttaa ttttgaatca
      121 aattttgaat aatttgactt tccctgtcgg ccgtcgagct aaaccttccc gccgacaggc
      181 ggccccaaat cgtaattaac caaattaacc gaataatacc atgaaaaaca aaattgaaac
      241 ttggaaattt atcgtgcaga ccatcatcgc cgtgctcacg gcgatcgcca ctagcctcgg
      301 cgtggctagt tgtatgaact gaactaaccc ctccccatcc ctcccgaggg agggggttaa
      361 gtctcccctc ggggagattt agagggggtt ggttgactac gtaggcactc ccctccccta
      421 catgggaggg gagaaaacaa cacaatccaa catcccctcc ccgaccctcc cgagggaggt
      481 gggaatccag tcctttttct atctgatttc tactttaatt gatttcaatc taaagaatct
      541 gctgagcctc tactgaaacg caaaaaaaag gattaccctt agatttttcg cttgacccct
      601 aaatttctac tgagcccttt aaattcatta aacaattatt attgcacaag aaaaagcgaa
      661 acttttcttc tcttaaagtg gcacttttct ctttttattt cgtacctttg caccaaccta
      721 actaaatagt attacaaaat gagaacaacc attatcacag ttgctatatt gctgggagcc
      781 ttaaatagta tagaggctca agaaaaagtg atgagcatac tgaaaaccaa cggtagcagt
      841 agtaaaacac gagtagtaga actagaccaa atcaagtttc taccatttga cattaaccat
      901 ctgcaacaac cttcgagtga aacccagagc cagcctgcaa ccatgatcat gaaactgatc
      961 aacggtgcac agatgcgcac cagtgtggac gaggtgaagg acatttcgtt tgctgacaca
     1021 ctctatcata ccaacagtat gggacagcac atactggaaa cagacgagct gatttggccc
     1081 gacgatcgac tgctgccaca tctgttacca ccggcctcta cgatcaagac gctcgacatg
     1141 cctgccgcac gactgggcaa tgccgaacgt gtcatgttct gcacactgca aggcatcgtc
     1201 aaccgcacct gtccacgtat tctgctctat aaccacaatg aagagccaca aagcacatgg
     1261 ccatctgcca acggactgag aacgagtgcc atttcaacag ggaatcccta cgaactggtg
     1321 aagtcttata tggaagagct caacggacta gtgctctaca ctaatgagtt gagcgaccat
     1381 tatgccaacc tggctgttac cattggcgga cttgacagac tattgcccgt gacacctgag
     1441 gtgaaagaaa aacttgaggc caatggcatt caactgcctg taaaggtcga tctgacgcaa
     1501 ctcaccatga gtacagccac cgacatctat acttacctct acgacaacta ctggcagcgc
     1561 tgcaaccatc gattgttaat aagcctgaac cctaccatcc cctacgtaca cgacatcggt
     1621 gctgcatgcg gatctgcatg tgtttggctg gacccacgca tacagagtga acgaaacgtg
     1681 ttggacaaaa tgctgaccga catgacccct ggacgcgaca tcgtgctggg atggtacccc
     1741 gaagagcgat cgggtgttgg cgaagctacc aaatacggac tgtcaaccgt gcctgccgac
     1801 ttctttgaaa atgctactgt ctattctgct gtcaacactc ctatcaagat tgctcctgtg
     1861 ccccaacgtc ccaagctgga aaataagatt tatgcagccg tatatatcag tgatggcgac
     1921 aacatacagt attgccagca tgcaatggca aagattttcg agcaaggcgg ccgaggacag
     1981 atgccgatga actggaccat tagccctgct ttggcagact ttgcgccggc catgctgaac
     2041 tactactatg gtaaggcgtc aaacaacgac tgctttgtct gtggcccttc aggacttggc
     2101 tatgccatgc cttacgatgc ccacaataat aaatattata gtaactatgt caaaactgag
     2161 ccgtttaaca aatacacgca gctcacgcag cgataccttg agaaaaccgg tcttcgcatc
     2221 atcaccatct gggacaacat tcacaacaga caaggcaact gctatgccaa caactgctcc
     2281 tatctctatg gactgaccat caacgactgg gaacgtcaaa acggccgact ccagggatcg
     2341 attcaatcgg gtacactgcc tattgcgcca caatatccat gctacgccaa tagcacagat
     2401 gtggtcacag acttcttcaa tcgagacatt aagaactttg acggcaccaa acctatgttc
     2461 gtcacaggac aggtcaccgt gtgggacgta ggcccagata agctggtagc tcttaaagat
     2521 aagctcaata cgctttcgcc aggcaacgtt agcatcgtgc gtgccgacca ttggttcagc
     2581 tactatcgcg aagcaaatca tctaccattc aacatcacca tgctgcaaga catgaagatc
     2641 acctgttcct ctgccaagac gcctgcaaga tatgctgcag acgggtcacc atcatcaagc
     2701 aacacatgga tttcaagaca gtcgaaaaat caaggatgga tacagatgga ttttcaagag
     2761 ccctacgaaa tcagccgcta tgtgatacgc catgcagaga catctggact cgacccagaa
     2821 ctaaacacac gtgatttcac tattgagctc agtatggacg gtgagacatg gaccaccatt
     2881 ggcacctata ccggcaacac agcccctgtg accgaagcca acatcacgcc cacacaggca
     2941 cgatatgtac gactgaacgt cactaacggc ggtgcagacg gatatgtgcg catcggagat
     3001 attgagatag aaggagcgca ttaataaaag agggagcaca ttgaattttt taactctgcg
     3061 ctcccttatt tttctttgcg atttcgatcc atgttctcta atttttgaca taacaaccaa
     3121 gaataatgag atgtagtttg gttaatagca aaaaacttag tacctttgca aagtattcaa
     3181 aaaacaaacc tgaccgctat taactaatta taagaatcaa cccttattgt agttagtata
     3241 tcttcaactg aagacatttg tgtgtcaagc agttagcaac gagtatagtg gtatattata
     3301 acctctatct ttatctcaaa ttattatact agactatttt cttatatgaa tagctgtgcg
     3361 atgcctccca aacgaaagag gcatcgcaca agtgttttta ttcaccctta tagagcgact
     3421 ctagacggat gtcgcgagct tgacgcaggt aggcattacg ctgaacaaca gctcgtaccc
     3481 actcgtcagt cagcaagttg gctacaggca agttaagctg ccatcgtcct tgtgcttcca
     3541 gccgatctac catcacgccc acgctcaggt tgtcaagact ctcggctgga agatagcgcg
     3601 actcatcacc tttctcatca ggagtgatct ctatcaacag acgcgcttct tgcaattgat
     3661 acaacaggtc ataaaccaca cgaatgggaa tgcctgacga ctgtcgcagt tcttcggctg
     3721 taggcccacg gcgcccggcg gcaaaacggc ggcacacgat gctcatgagc aaggcactaa
     3781 gcattagctg atagcgatgg ctaatatcct ctgtacgacc attatagaca tagtagtcaa
     3841 ggttctgcga agtataagtc aactcggctc caaaaagaca gatggtccag gagatttgta
     3901 cccacaacat aaacataggt agcgcagcaa atgaaccgta aatggcatta taccccgtga
     3961 cccacatctg agaatgaata tagaagaact gaaccagctg catggctatg cccgacaata
     4021 tgcctgggat aattgcattc ttaactttga catgcgtatt gggcataaac acatataacc
     4081 caatgaacaa tagcgacatg aggatatagg gcgacatatc tatgagtttc ctgacaaacg
     4141 atcccaataa taggaaatcg gtcatcgaat cggccatcgt ggctaagaaa aggctgagac
     4201 cggtagagat aacaataaaa atgggaaaca ggaagaacat ggcgaaataa tcggttacag
     4261 tacgaaaaat actgcgtttt ctcttcacct gccaaatctc gttgaaggca atctcaatgt
     4321 gatttaccag cagcatcacg gtgtaaagca taaagataag acctacgccc aagaagatac
     4381 cactcttggt gtgcaccaag tagctattga caaaacctat gataacctca gccacttggg
     4441 gttgcgacga gaaggcatcg cgaaaccata gctctatata acgattgtag ccaaaaccac
     4501 gggctatggc aaagataacc gccatgatag gcacaatagc caacagcgta ctgtatgtca
     4561 gagccgaagc ctgattaacc acacgctcct tcgtaaaaaa gcgaatagcc agataggcta
     4621 ttttataaac gggcaactgt tgaagatttc taacttttga tttcatcgag gttaatcatg
     4681 tagcgtaaag agaaaaaacg aaagcagcgc ccctataagc cgggttctgt actgacaaaa
     4741 agtcagcgcc tgccatttat ctactacgta cgtcaccata cgtctctagc gttctaccct
     4801 ccatcgcatc ctcaaaggaa ctcgagcggg caaccctcaa ttggcgatgg tatacatgaa
     4861 cttgcagtct ccagatggaa cagcccaacg atcacccgct ggctggtggt ctcttacacc
     4921 accttctcac ccttacctta tataaatatg aggcggttat tttcttcttc catatccagc
     4981 tgtcgccaac tgcttctact ttcagaagtg gagcacccta tactgcccgg actttcctct
     5041 cgtctctcct ttcagaaaca ccagcggcaa gccggaacgc tgctttcgcg agtgcaaagg
     5101 taatactttt ttttgaatga tgctaatttt tgtttaattt aaagaattaa atgaatgtaa
     5161 aaatactgtt ggcagtcgca aacggacatt aaaggcgtgg cacgaaatgt taaaatcaaa
     5221 caaaaagaac ggacatattg tcagttttta aacttttgcc catatatttg catcaaagga
     5281 ttacacgaaa ttataaacat taacactaat atgaagatta tggataagaa aaagattgct
     5341 aattatgtta tcccggccct cagcttgacg gccatcgtat tctcggtagc agcttttaac
     5401 cagacaaacg cagccaatgt gctggctgca aatccggaga ccacagaaat ctctaacctg
     5461 ccggccgcac agccagtaga tttgacatac gctgcagaaa aagcgctccc aactgttgta
     5521 catattaagt atgtgcagaa ctcaaaaatc cagaccgtag aggtgcaaag cgaccccttt
     5581 gaggattttt tctctgaccc attcggcgga ttcttcggac gcggacagcg cggacaggga
     5641 ggtacacgca aacagaaggt gcagacacct aaaaaaactg ccacaggtag tggtgttatc
     5701 atttcaaccg atggctacat tgtgaccaac aaccacgtgg tggatggtgc cgacgaactg
     5761 accgtcacct tgtctgacag taaggaatat tcagcacgca tcatcggagc cgacaagacc
     5821 accgacttgg ctcttatcaa gattgacggt aagaacctgc cagccatccg catagccaat
     5881 agcgataatg tgaaagtggg cgaatgggtt ttggccatcg gcaatccttt gggactgaac
     5941 aatactgtga ccgctggtat tatctcagct aaagctcgta cactgggcgc caatggcgta
     6001 gagagcttca tacagaccga cgcagccatc aatgcaggta actcgggtgg tgccttggtc
     6061 aacaccaatg gtgaattggt tggtatcaac gctatgcttt attcacagac tggttcttat
     6121 agcggctacg gattcgccat tcctactgct atgatgaaca aggtggtaga agacctgaag
     6181 aagtatggca ccgtacagcg cgccatgatt ggtattggcg gacacgacgt caaggcccag
     6241 gtggacctcg aaaaggaaga aggcaaggag cctaccgact acggcacaat ggaaggtgtc
     6301 tatgtaggtg aagtattaga ggaaagcgct gctgcagaag caggtatcga aaagggtgat
     6361 atcatcatcg aggtggacgg caagaaactg accaaatatg gtgagctctc tggtatcctg
     6421 gctcagaagc gtcctggcga caaggtaacc ctgacctact tgcacaacaa aaagaaacag
     6481 acgaagactg tcactttgcg caatgagcaa ggcaatacca aggtagtgaa gaatgccgac
     6541 atggatgtac tgggagcaga cttccgcgaa atcacgaaag cacagaagga acagcttgag
     6601 atcagctacg gattggaggt actgaaagtg aatgctggca aaatgaaaga agcaggcatc
     6661 cccaagggct tcatcattca gcgcgtaaac gacgaacaaa ttaagtctgt cgaagacctt
     6721 caggaggtag ttaaagaagc ttcaacttcg aaagagcctg tgctgatcat caaaggtcta
     6781 ttccccacag gaaaacgcgg ctatttcgta gtacaattga gcgagtaaac gcattgtatt
     6841 gttaaaagtt attaaaagga ggaaaaaagt taagacaaaa cactttttcc tcctttctct
     6901 ttactatctt tgcgctctat agactttaac actggtacct gatgagacaa cttaaaatta
     6961 ccaaatcaat cactaaccgt gagagcgaag ctctcgacaa atacctccaa gaaatcggca
     7021 aagagtcgat gatcagcacg gaggaagaag ttgaacttgc ccaactgatt cgcaaaggcg
     7081 acaggaaagc gctagagaag ttaacaaagg ctaatctgag attcgtagtc tcagtagcta
     7141 agcagtacca gaaccaggga ctgtccctac ccgacctcat taacgaaggt aatctgggac
     7201 tcatcaaagc cgccgagaaa ttcgatgaga cacgcggatt taaattcatc tcctatgctg
     7261 tgtggtggat taggcaaagc atactgcaag ccatcgctga acagagtcga atagtgagat
     7321 tgccactaaa ccaggtgggc tcgatgaata aaataaaccg agtggctagt aagttcgaac
     7381 aagagaacga acgcagacct tctgctcgtg aattgtcaga acacatagat ttgcccatgg
     7441 agaaaattga tgaagccatc aatatttccg gaaagcaagt gtcggtagat gccccttttg
     7501 ccgacggaga agaaagctca ttgctggatg tactagtgaa cgacaattca ccatcggccg
     7561 accgcgaact ggtaagagaa tcgttacagt cggaaataag agatgtgctg aaggaactga
     7621 gcgagcgcga acgcaatatc attatggcat tctttggcat agatcagcca gagatgacat
     7681 tagaggagat tggtgtgcga tttggtttga cgcgcgaacg agtgagacaa attaaagaaa
     7741 aagctattcg acggctgcgt tgcaacgcta agaacaaggt cttactcagc tatttagggg
     7801 cataaaagcg atttcaatag agtattaaca cacaagtaaa tagaaagttt tgaaacatct
     7861 aacactcatt atgatgttgg cagccttatt tggaactgcc acaactgtta aggcgaaaaa
     7921 agtagtagtg cctaagatgt atgtctttgg cgtagcagcg tctttcaacg acacaattgt
     7981 acacttcaca gacattcagg aagttgacag cgcttggata gacaagaaaa caaaatttct
     8041 ggctggccga gacaactatt catatcagct gcgtgattac ttggaacagc agcagatgcc
     8101 ccatcgcact tgtatcgtat tctataataa gcagcgctcc aaacttgaga agaaatatct
     8161 caagatgaag cgtctataca tgcctggcaa ggacggaaag gtacacttcg acctgcgtca
     8221 tctgaaaagt ggcgacttca aattcatggc atacgacgcc agcgaagatg agaaatagtc
     8281 actatttcac aatagctgag cacaacatct gcatcaactt tactgatggg cagaaaaacg
     8341 cgatggaact gttgccatcg ttctgtcagt ttagtacaaa tgcgccacaa gaagaacttc
     8401 tcttcacatt aaccattgac gacacgctat cgcctagaaa ggacaaaacg ctggtacgaa
     8461 agtttgacac aggaaatggc gacacaattg tttatcagtt gagtgacgga ggttatcagt
     8521 atgtcatacg agatacacat ggtcgcgact gttgcttact gataagcaac agaacattca
     8581 atgagtgcca atgtgcactt aatggtgatt ggaccatgcg ctcattcgga ctgaatgatg
     8641 cgttgatgct catttatgcc ttcgctggtg cctatcatca caccatgctg atacatgcat
     8701 catgtattaa atatggagca tggggattcc cttttaccgc taagagcggc actggcaaga
     8761 gcacacacac ggcactttgg atgaagtaca tcgacggagc agaactgctg aacgacgaca
     8821 atcccatcat acgtatcatc aataacaaag cctacattta cggctcacca tggagcggaa
     8881 aaacgccctg ttatagaaat gtgaaaacgc aattagctgc cattaccact atttgcagag
     8941 cacccgaaaa ctcaattcaa aagctaggac cagtacaagc atttgcctct cttttgcctg
     9001 catgttcaag tatgatgtgg gattctgata ttcacaattt tctctgcgac gacctcacac
     9061 agttaatcga gaaaacacct atctacacgc ttcattgcct accaaacgaa gaagcagctc
     9121 agctatgcta caagaccatc gtaccataac aacaatccaa atggacaacg accagttcct
     9181 gcctcaggtg gtgaatctgc tgcaggaagg acatacggtc actctgcccc ttcgtggtcg
     9241 tagtatgcga ccattcttgg aggacggacg cgacaaagct ctcttgaaaa tagccaaaca
     9301 ctatgccgta ggagatgccg tgcttgctga aatagccaaa ggtagttttg ttctgcaccg
     9361 cattatcgct attgatggtg acgatgtgac attaaggggc gatggtaatt tgaacaacga
     9421 atattgcaaa ataatagaca tacgcgctaa agctatcgga ttctatcgaa aaggacgtaa
     9481 caaacttgac agtaccgacg gttgcaaatg gcgtatatac tcatggtggt ggacacgtct
     9541 ctactccatt cgacgctatc ttttgtttgc tatgcatcca cacataccac gtagatggag
     9601 aagacaaaca tcttgactga taataaacga ataaaaagga tatgaaaaca aaaaaaggat
     9661 ttagacttcg caacatatgc ggtgaaaatg tgattgtagc tgaaggtata gagaatattg
     9721 acttcagtcg tatcatcagc atgaacgaat cggctgcata cctgtggaat aaagttcaga
     9781 gcattgactt tacagccaac actctgatag atttactatt agaagaatac gaagtcagca
     9841 gagaagatgc cgctcaagat gttaaccagc tcattgaaca atggcaaaag gcgggcatcg
     9901 tagaggatta gagttttaaa atctgcttga acatcccatc gaattcagat tccagcgatg
     9961 gctcatgact gaaaatgcca aatacagcac ttccactgcc actcattgcg gcatattcag
    10021 cacccatatc gtagagacgt tgtttgatag caccaatttc aggatgtaaa gcaaaaacac
    10081 tcttttcgaa atcgtttttc aaatcatgtc gccatgaact gattggctgc tggacaacat
    10141 ccctacagtt cttttctgga cgagcgggag tgatcaacga aaatgcttct ttcgttggta
    10201 caggaatatc tggacgtacc actgctagcc aataatcatc taaactgaga tcaataggca
    10261 taagttgttc gcctatcccc tcggcataag atggtgtatt caacacaaaa aatgcgcaat
    10321 cggcacccaa acgggccgca tagccaataa gttgttgctc ggtgagtcca agctcaaaca
    10381 ttctgttcag caacactagc attgccgcac agtcgctact acctccaccc attccggctt
    10441 gcgtaggtat agccttatat aaatgagcat gcacgcgagg catctgagga aaatcttgtt
    10501 ttagtaggtt ataggcctta accacaagat tcttttgttc atctccctct atcgcaatgt
    10561 tcgacacctt taagtcacaa tcataatcag atggaaatgc ttcgtccatc actgttacct
    10621 cgagcgcatc tttcagcgca acaggaaaaa acaccgtctc cagattatga tatccatctg
    10681 tacgacgttc aaccacattt aaaccaaggt ttatctttgc tataggaaaa ataatcatct
    10741 tatatttatt tattggtgca aaagtaatca ttttcacgga aaaagacaaa ccatatcaaa
    10801 aaaaatacgt acctttgcaa ttcaaacgct ataattagta tgccagaaca aaatacaacc
    10861 aaaagacgta gtagaaagca acagccagtg gacaacacct atgcacacct gcagccacag
    10921 gcacttgaca tagagcgtgc cgtacttggt gccttgctca ttgacaaaga tgcatattcg
    10981 gtggtttgcg agatgctctt ccctgagagt ttctacgatc cacgtcacca gatgatctat
    11041 actgctatcc gtgacctcgc gatggcagag aaaccggttg acgtactgac cgtaactgag
    11101 caaatggcaa agaacggaca actggaagag gctggtggtc cgagctatat tgctgagata
    11161 tcgacacgta ttgcttcttc tgctcacgtt gactaccatg ctcgtattgt agctcagaag
    11221 ttcttggcac gtcaactcat ccagtttgcc ggtgatattg aaacaaaagc gttcgatgag
    11281 acaattgatg ttgacgaact gatgcagcag gcagagggtg ccctcttcga actttctcag
    11341 aaaaacatga agaaggacta cacccaaatt gatccagttg taggtcaggc aatgcaagcc
    11401 atacagaaag cagctggtaa ttctggcggt ttgacgggtg tgcccacagg ttatcataaa
    11461 ttggacgata tgaccagtgg ctggcaggcc agtgaccttg tcatcattgc cggacgacct
    11521 gccatgggta aaacgtcatt tgcgctctct atggccaaga atattgcagc cgactatcag
    11581 gttcctatgg cattcttctc acttgagatg tcgaatgtgc agctggtaaa ccgtctgata
    11641 tcgaactgtt gtgaaattca aggttcaaaa attctaaacg gacaacttca acctgacgaa
    11701 tgggatcgtt tggataaacg catcaatggt ttgctaggtg ccccactcta tgtagatgac
    11761 acccctggtc tttctgtatt cgaactacgt actaaagctc gccgattggt gcgcgagcat
    11821 ggcgtaaaaa tcatcatgat tgactatctt cagttgatga atgcaaatgg catgcgtttt
    11881 tcttcacgac aggaagaagt gtcgaccatt tcacgttcgc tcaaaggatt agccaaagag
    11941 cttgacgtgc ctattttggc tctgtcacag ttgaatcgtg gtgtggaaag tcgtgaaggt
    12001 ttggaaggta agcgcccgca actgagcgac ctgcgtgagt cgggagccat tgagcaggat
    12061 gccgatatgg tattgtttgt ccatcgtcct gaatattatc atattttcca agatgacaat
    12121 ggacgcgacc tacatggcat ggcacaaatt attattgcca agcaccgtaa aggtgcaaca
    12181 ggtgatgtgc tattgacctt ccgcggtgaa tacactcgat ttgagaatcc tgaagacaca
    12241 cgtttggaaa accgagcgcc acaagatggt ggaggtgaaa ttcttggatc gcgcgtcaat
    12301 ggtgagaata atattccaga taattttgac ccctttggag gaagtccact accgccacca
    12361 cctggggacg cacccttctg attggcagca actcatacct tcatgagttc tgccataatc
    12421 atatcgctaa cgaaaagccc ctcacgcgtc agtatcaaat ggttgtcaac taatttaagc
    12481 caaccattcg aaaggtattt ctgagacatg ctcaaacagt actggcgctg ttgaggtgtg
    12541 agtagttgca acgagagccc gtcacaagta cgtagtgctg tcattaccaa gtcattatag
    12601 cgagttgact catctaactc ttcgaagtcc acatgctgta aaccactctc aattccttcc
    12661 aaatattccg aaaggcttga tacattccat tggcgtttga atccatcata gctatgagcc
    12721 gcagccccaa gtcctatata tggtgtttga ttccaataac tggaattatg gcgtgagcga
    12781 cagcctatac gggcaaaatt actgatttcg taatgttcgt aacccgcaga agcaaggcga
    12841 tcaataagtt caaaatacat ttgacgctct aattcttcat caatctcgtt cacctctcct
    12901 ttctccagca ttctataaag tgctgttccc tcctcatatt gcagggcata ggccgacaaa
    12961 tgttctacat caagagataa tgccttgtta atatcgagga gccactcaga aagagtttgc
    13021 tgagggaaac catacatcag atcaatactt atattggaaa caccggccct tcgcagcaac
    13081 tcgacagatg gagcaatttg atcagcatta tgacggcgac gcaaaaagcg cagacgatca
    13141 ttattaaacg tctgtacacc cattgacact ctgttgacag gcaattcgct tagcgactct
    13201 ataaactgtt gtgttacgtc gtctggatta cattccatcg tcacctctgc taaagggtct
    13261 acacgataca ccttatatat atatgaaaag agctgcttaa gttgctgaga agagagttgt
    13321 gagggtgtac caccaccaag ataaatggta gagattatct gctgagattg tctgcattgc
    13381 atctctttac acaatgcatc tacgtatctc tgagataagt caagttgcgt ggtcgaaaag
    13441 aagccacaat acacacaacg actcgcgcaa aagggaatat gaatatatag tcctgccata
    13501 atcgctacaa aattactaat tttgtttaat tttcaaaagt tttttttggt atttaggcag
    13561 aaaatgcgta ctttagaggc ctcaaaccta agggcgagaa gagaattacc aataaattat
    13621 taataactaa aacctgtaac actaatgaaa gtttatcaga ccaacgagat taaaaacatt
    13681 gcattgcttg gcagtgcggg tagcggcaag actactcttg ccgaagcaat ggtttacgag
    13741 gccggcatta ttaagcgtcg cggcaccgta gagggtaaga acaccatgag cgattatttc
    13801 cccgtagaac aggaatatgg ctactcggtg ttctctactg tttttcatgt agaatggaac
    13861 aacaagaaat taaatattat agactgccca ggttccgacg actttgtagg tggtgcaatc
    13921 acagcactga acgtcacaga ccaggctgtc attctgatta atggtcagta tggtccagag
    13981 gttggaacac agaatgcatt tcgttatact gataagttgc aaaagcctgt catcttcctg
    14041 gtaaaccagc ttgataaaga gcattgcgac ttcgatacca ttctgaacaa catgaaggaa
    14101 atctatggcg agaaatgtgt tcctgtgcag tatcccatat ctaccggtcc cgacttcaat
    14161 gcagtcattg acgtacttct gatgaagaaa tactcatgga aacctgaagg tggtgccccc
    14221 atcattgaag atattccagc tgaccagatg gagaaagcta aagaacttca tgccgccctc
    14281 gtagaggcag ctgctgccaa cgacgacact ctaatggaga aattctttga aagtgagagc
    14341 ttgacagaag acgagatgcg cgaaggtatc cgtaaaggac ttgtgacccg cagcatcttc
    14401 cctgtattct gtgtatgcgc aggcaaggat atgggtgttc gacgcctgat ggaattccta
    14461 ggcaacgtgg ttcctttcgt tagcgagatg ccaaaagtgc gtaatacacg cggcgaagag
    14521 gttacccctg atgccgctgg tcctgcttca ctctatttct tcaaaactgg tgttgaacct
    14581 catattggtg aagtacaata cttcaaagtg atgagtggat cggtaaaaag tggtgatgac
    14641 ctgaccaatg ccgatcgagg ttctaaagaa cgtatcggta ccatttatgc ttgtgccgga
    14701 gccaaccgca ttcctgttga cgaactaaaa gctggcgata tcggctgtac ggtaaaactt
    14761 aaagatgtca aaactggcaa tgccctaaac ggcaaagatt gcgagtggcg ctacgacttc
    14821 atcaagtatc ctaattctaa gtactcacgt gccatcaaag ctgtaaacga agcagaaaca
    14881 gaaaagatga tggttgctct tacaaagatg cgtcaggaag atccaacttg ggttgtagag
    14941 cagtcgaagg aattacgcca aattattgtt cacggacagg gcgagttcca tctgcgcact
    15001 ttaaaatggc gtatggagaa caacgagaaa atcaagattg aatatttgga gcccaaaata
    15061 ccatatcgtg agactatcac caaaatggct cgtgcagact atcgtcataa gaaacaatca
    15121 ggcggtgccg gacagtttgg tgaggtacac ctgattgtag agccatatgc agacggtatg
    15181 cccgatccca catcattcaa gatcaatggc caggagttca agatgaacat caaaggtaag
    15241 gaagagattg acttagaatg gggcggcaaa ttggtattca tcaactctgt agtaggtggt
    15301 gcaattgata tgcgtttcat gcctgccatc ctaaaaggtg tgatggaacg catggagcaa
    15361 ggaccactga caggttcgta cgcccgtgat gttcgagtga ttgtttacga tggtaagatg
    15421 cacccagtag actctaacga gctctcattt atgcttgcag ctcgcaatgc tttctcggct
    15481 gcattccgcg aagcaggtcc aaaggttctt gaacctattt atgaccttga ggtatatgta
    15541 ccatccgatt atatgggcga tgtaatgagc gacctccaag gacgtcgtgc catcattatg
    15601 ggaatggact cagaggcagg ctatcagaag ttatctgcca agataccttt aaaggagctt
    15661 tctaactact ctatcgcact aagttcgatc actggtggtc gtgcatcctt tacaacaaag
    15721 tttgctagct acgaactcgt gccaaacgat atccaacagc aacttattaa ggagcacgaa
    15781 gctgagctca aagacgaaga ctaataattc acttcatacg aagttatcat acaaagagac
    15841 cttaggcatt ataagcccaa ggtctcttta tttacatcaa ggggtataat atttagtaat
    15901 atataagcaa ccaacaatat tgtttcatgt taatattgtt aaaattaaca gaaataatta
    15961 acttaaaaag aactatggtg ttgaatttca cttatctttg cgacatcgtt attaaatagc
    16021 agaaaagatg aagaaatcta cgatatggat tatagcagcc gtgatgggaa cttcgttctt
    16081 aggattgctt tatttgcaaa tctcctacat cgaagagatg gcgaagatga agaaggagca
    16141 attcgacgag agcgtgacac gtagcctcta tcaggcatca cgcaacttgg agctgaatga
    16201 gacacttcgc tatttggaga aggacgttaa cgaagtagaa cgaaaagcat tcacacaaga
    16261 ctccgtcatt gtaaacagcc ttgatggctc catccagcat gctcatcaat tctctgtttc
    16321 tgctgacgac ggtacattct attctgcttt tgaactcaag acttttacaa caaagcctgc
    16381 ctcagtgcca aaagcaatga taatgcattc agacaaaaat cagaaatctg aagcagccaa
    16441 gacactccaa gagattgtgc gcaatcgata tgtctatcag aaagctctgc tcgatgaagt
    16501 ggtctataat atcttatata cggcaagcga gaagccacta aaagagcgtg tcaacttcaa
    16561 actgttggac caggacatcc gctccgagct catgaacaac ggcatcagca tcccctatca
    16621 ctttactgta tctacagccg atggacgaga gatataccgt tgtcctgatt attctgatga
    16681 aggtgatgaa tatacctata cgcaaacgct ctaccgtaat gatccctcat cgagaatggg
    16741 cgtggtaaag atacacttcc cagacatgag ttcgtacata ttctcgtcaa tcagattcat
    16801 gattcctgcg ttaatattca cgatggtttt gctgctaaca tttatcttta ctatagtagt
    16861 gatcttccgt cagaagcgct atacagagat taaaaacgat ttcatcaaca acatgactca
    16921 cgagttgaag acaccgattt cgagcatctc gctggctgct cagatgatga acgatgacag
    16981 tgtgactaag agtcagtcca tgatgaaaca cctcagcggt gtgattaacg acgagtcaaa
    17041 gcgtcttcgc ttccttgtag agaaagtgct ccaaatgtcg atgttcgaca gaaagactgc
    17101 ctcgttcaag aagaaagaac tggatctcaa cgaactgctt gaacaaactg ctagcagttt
    17161 caacctgcgc gtagaacaca ctggtggtaa tataaccaca gaaatagaag ctatcgactc
    17221 tgcaatctac gttgacgaag ttcatttcca gaacgctatc accaatttaa tggataatgc
    17281 cgtgaagtac cgtaaacccg acgaacccat taatatccat atacgtactt ggaacgaagg
    17341 aacaaacctg ctatgtttca gtattgaaga taacggactt ggaataaaga aagacaatgt
    17401 caaaaaggta ttcgacaagt tctatcgagt tcatacgggt aacgtacatg atgttaaggg
    17461 ctttggactt ggcttggctt acgtaaaaaa gattattaat ctgcacgatg gtgaaatcaa
    17521 atgcgaaagc gaaatcggga aaggcaccaa gtttacagtc aagttgcctg tactgaaaga
    17581 ggatagtaca caatagcccg actaatatag aataaataaa gataaataaa ttaagtatta
    17641 actcggagga aagaactctg ttctaccccc catcccctaa tacagggggc aaaaaagaaa
    17701 agaatatgga agacaaactg aaaatcttac tttgcgagga cgatgagaac ctcggaatgt
    17761 tgcttcgcga atacttagca gctaagggat ttgaggcaga actctgccct gatggagatg
    17821 ccggctttaa agcattcatg aaaacgaagt tcgacatctg tgtacttgac gtgatgatgc
    17881 ctaagaaaga tggttttaca ttggcacagg agatacgtag cgcaaatgct gacatgccta
    17941 ttattttctt gacagcaaag actttgaaag aagatatcct cgaaggattt aagttgggtg
    18001 ctgatgacta catcaccaaa cctttctcaa tggaggaact tgtattccgt attgaagcaa
    18061 tcttgcgccg tgtacatggt aaaaaaacaa aagagtctac cctctaccat atcggcaatt
    18121 ttatattcga tacacagaag caactgctca caatgggtga caaacagacc aagctgacta
    18181 ccaaagagaa tgaactgctt gctttgcttt gctcgcatgc caacgaaatc cttcagcgtg
    18241 atttcgctct gaagaccatc tggattgatg ataattattt caatgctaga tctatggatg
    18301 tttacatcac aaaactacgc aagcacttga aggacgatcc acaaattgag attatcaaca
    18361 ttcatggcaa aggctacaaa cttattactc ctgaagagca ataataactc tttttgagaa
    18421 attggaatta caataaaggc ggagatgaaa gaaaaaacat ccccgccttt tcttttttac
    18481 ttatttaagc ctaaaatttg cttatatcgg aaaaacttag tatttttgcg ggctgaaaca
    18541 attttgaata cagagaagaa gaagatatga ggaaacggtt tgtaattacc ttgtggtcaa
    18601 tattgacttt catcgttctg tcaactgcaa tatgtttttg ggccatctca aacggatata
    18661 ttggctacat gcctcccata gaagacctac agaaccctat cagccgctat gccacacagg
    18721 tactttcctg cgacaataaa ctactgggga catggagcat gagtcgcgaa aaccgcgtat
    18781 tggtcaacta ttccgaccta ccagaaactc ttgttaatgc attagttgca actgaagatg
    18841 cacgcttcta tgagcactcg ggagttgact tctatgcact aggacgtgcc atcattaagc
    18901 gtggcatatt gggacagaaa aatgcaggtg gtggttctac catcacccaa cagctggcca
    18961 agcagctatt cagcgatgtt gctaagaata gtatggaacg agctttccaa aagcctattg
    19021 agtgggttat tgctgtcaaa cttgagcgat actacacaaa aaatgagatt atcgccatgt
    19081 acctcaacta cttcgacttc ctgcacaatg ctgtaggtat taaaactgct gccaacactt
    19141 atttttcgaa ggagccatca gagttgacac tgacagaggc tgcaacacta gttggcatgt
    19201 gcaaaaatcc ttcttacttt aatccacgcc gctatccaga gcgttgcatt gagcgtcgca
    19261 atgtggtatt agggcaaatg ctcaaagaag attatatcac tcaagaggag tttgatagtt
    19321 gttgccaagt gccccttaac ctacgttttc atgtagccga tcataatgca ggaagcgcca
    19381 cttatttccg cgattttctt cgccgataca tgacggccaa gaaaccccag cgcgacaact
    19441 atccagaatg gggatatgtg agtttctacc ttgactcgct ggcatgggaa caagacccac
    19501 tatttggttg gtgcaacaag aacaagaaac gtgacggcag ttactacaac atttacaccg
    19561 atggactgaa ggtctatacc actattgact cacgtatgca acaatatgcg gaggatgctt
    19621 gctatcagca cgtggttaac tatctacaac cggccttcaa ccaatcactg aaatacaagc
    19681 gcaatgcgcc atactcaagt tctttatcag atgaagaaat acagcgcatt cttcagcgca
    19741 acgtgcgcca gagtgaacgt tatcgagtga tgaaagctgc tggtgcttca caggaggaga
    19801 ttgaccgggc ttttaacacc aaaattgaga tgacggtctt cacatatcgg ggcgagaaag
    19861 acacgattat gactccaatg gattctatcc gctattataa gactttcttg c
//
