LOCUS       c00082_NZ_FQXK..       12561 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FQXK01000046.1 Butyrivibrio fibrisolvens DSM 3071, whole genome
            shotgun sequence.
ACCESSION   NZ_FQXK01000046
VERSION     NZ_FQXK01000046
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:57:33
            Original ID  :: NZ_FQXK01000046.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12561
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12561
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1109:2561](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1110..2561
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..12561
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12561
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             1110..2561
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_1"
                     /sec_met_domain="PF04055 (E-value: 4.1e-14, bitscore: 44.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.9e-16, bitscore: 50.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.3e-20, bitscore:
                     63.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 5.8e-30,
                     bitscore: 94.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHIFKNNGYNIVLDVNSGSVHVVDEIVYDLIPSVEEILTGMFGT
                     AQIPENEEDSEISKELLRKVTDAVVAKGTSYPESEVEEAVEEILSLRQAGLLYTDDIYE
                     NYVEEFKTRDTVIKALCLNIAHDCNLRCKYCFADEGEYHGRKAMMTFEVGKAALDFLVK
                     NSGDRHNLEVDFFGGEPLMNWEVVKQIVEYGRSIEKEAGKNFRFTITTNGTLLTKEILD
                     YCNKEMGNIVLSIDGRKEVNDKMRPNAAGHGMYDMIVPKYLEVAKSRHQLRYFVRGTFT
                     HNNLDFAEDVKHLADLGFKQISMEPVVAKPEDWYAIKEEDLPQLKEEYDKLAKIYLQYR
                     KEGKGFNFFHFNIDLSGGPCVAKRLSGCGSGCEYVGVTPWGDIYPCHQFVGNEDFIMGN
                     VFEGIKRTDIQQQFKESNVYSRPECQKCFARYYCSGGCSANAYNFNGNINTVYKEGCEL
                     QRKRIECAIMIKAALAEEAEVKNAG"
     aSDomain        1113..2525
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_1_0001"
                     /evalue="4.30E-224"
                     /identifier="TIGR03974"
                     /label="ctg82_1"
                     /locus_tag="ctg82_1"
                     /protein_end="472"
                     /protein_start="1"
                     /score="742.4"
                     /tool="antismash"
                     /translation="VHIFKNNGYNIVLDVNSGSVHVVDEIVYDLIPSVEEILTGMFGTA
                     QIPENEEDSEISKELLRKVTDAVVAKGTSYPESEVEEAVEEILSLRQAGLLYTDDIYEN
                     YVEEFKTRDTVIKALCLNIAHDCNLRCKYCFADEGEYHGRKAMMTFEVGKAALDFLVKN
                     SGDRHNLEVDFFGGEPLMNWEVVKQIVEYGRSIEKEAGKNFRFTITTNGTLLTKEILDY
                     CNKEMGNIVLSIDGRKEVNDKMRPNAAGHGMYDMIVPKYLEVAKSRHQLRYFVRGTFTH
                     NNLDFAEDVKHLADLGFKQISMEPVVAKPEDWYAIKEEDLPQLKEEYDKLAKIYLQYRK
                     EGKGFNFFHFNIDLSGGPCVAKRLSGCGSGCEYVGVTPWGDIYPCHQFVGNEDFIMGNV
                     FEGIKRTDIQQQFKESNVYSRPECQKCFARYYCSGGCSANAYNFNGNINTVYKEGCELQ
                     RKRIECAIMIKAA"
     PFAM_domain     1479..1868
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_1_0001"
                     /evalue="3.90E-13"
                     /label="ctg82_1"
                     /locus_tag="ctg82_1"
                     /protein_end="253"
                     /protein_start="123"
                     /score="50.2"
                     /tool="antismash"
                     /translation="IAHDCNLRCKYCFADEGEYHGRKAMMTFEVGKAALDFLVKNSGDR
                     HNLEVDFFGGEPLMNWEVVKQIVEYGRSIEKEAGKNFRFTITTNGTLLTKEILDYCNKE
                     MGNIVLSIDGRKEVNDKMRPNAAGHG"
     aSDomain        2211..2468
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_1_0002"
                     /evalue="4.30E-18"
                     /identifier="TIGR04085"
                     /label="ctg82_1"
                     /locus_tag="ctg82_1"
                     /protein_end="453"
                     /protein_start="367"
                     /score="63.5"
                     /tool="antismash"
                     /translation="CGSGCEYVGVTPWGDIYPCHQFVGNEDFIMGNVFEGIKRTDIQQQ
                     FKESNVYSRPECQKCFARYYCSGGCSANAYNFNGNINTVYK"
     CDS             2574..3596
                     /locus_tag="ctg82_2"
                     /transl_table=11
                     /translation="MKKFKPVILIPVLLILLAVLCFYVFQGLTDYKENSSEDDDCSEYE
                     DGIHVTYEITYLNGDIPTDQDMEDIKELLTERIASEVEPEGSDEDSESEDKKSDLSENF
                     ESILPGNKDAVYKVNWVGSNRIEIYSQDVADVVIERITTTPELYFIREYNDTGSANYYD
                     PYGMGYAVFMELSEGVTIDSLKESGDIVLSAEDIADAQAGIDKSGAGSEYIVELTFTSE
                     GAEKFAAATESAYANGETIGIYYDGAFISVPRVQAVITDGKASITGMGSYESAEMLAKN
                     IRLGNLKLSEVETDSSDTVTDTENSIDTNIIIAIIGIIVIVLILFVFLVLGIYKAIVRK
                     "
     CDS             3695..5971
                     /locus_tag="ctg82_3"
                     /transl_table=11
                     /translation="MKKLKQVLPLVVVLAVLVGLFYVAWHGVGETQDGSMHDINFGLDL
                     AGGVSITYQVAGENGGTPTTQEMDDTVSKLSKRVASELNTTEASVYKEGSDRITVEIPG
                     ATDEIFETLSTPGNLYFIREYNDAGSANYYDPYGMGYSAFYMLADGVTIESLQASGDIV
                     LSGEDIADAQAGIDNSGTGSEYIVELTLTSEGAKKFATATEAAYANGWTIGIYYDGSFI
                     SVPKVQAVISDGKASITGMGSYESAENLASTIRIGGLDVSLTELRANVVGAQLGASAIH
                     TSKIAAIIGLILIVLFMVIVFRILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGII
                     LSIGMAVDANVLVFARIREEIAAGSAVDKAIKAGYSKALSAILDGNITTLIAAGVLGLR
                     GTGSVRGFAITLALGILVSMFTALVVTRGISSILFNLGFKAEGFYGKAKDPKKIDFVSK
                     RNIFYAISVIIMVAGIGTCVFNHVAGNHAFNYSIDFVGGTATTVSFAEGQTPSVEDLEN
                     VIEPAVINAASTADANLKNLSISHQIVKDQNQVVLKTQTLSTDASQAVHELLTTTYGAT
                     DVTYNTISATISDEMTSDASWATIIALILMLIYIYFRFRDIRFGASAIIALAHDAIMVI
                     MCYAFTRLEVGSTFIAVVLTIIGYSINDTIVTFDRIRENQHGIRSREQLKELVNESVNQ
                     TLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSSICIASQLWFSMKKK
                     SVEKA"
     PFAM_domain     3809..3859
                     /aSDomain="Sec_GG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07549.16"
                     /description="SecD/SecF GG Motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_3_0002"
                     /evalue="5.80E-03"
                     /label="ctg82_3"
                     /locus_tag="ctg82_3"
                     /protein_end="55"
                     /protein_start="38"
                     /score="16.2"
                     /tool="antismash"
                     /translation="INFGLDLAGGVSITYQV"
     aSDomain        3815..4981
                     /aSDomain="TIGR01129"
                     /aSTool="tigrfam"
                     /description="secD: protein-export membrane protein SecD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_3_0003"
                     /evalue="1.70E-98"
                     /identifier="TIGR01129"
                     /label="ctg82_3"
                     /locus_tag="ctg82_3"
                     /protein_end="429"
                     /protein_start="40"
                     /score="328.3"
                     /tool="antismash"
                     /translation="FGLDLAGGVSITYQVAGENGGTPTTQEMDDTVSKLSKRVASELNT
                     TEASVYKEGSDRITVEIPGATDEIFETLSTPGNLYFIREYNDAGSANYYDPYGMGYSAF
                     YMLADGVTIESLQASGDIVLSGEDIADAQAGIDNSGTGSEYIVELTLTSEGAKKFATAT
                     EAAYANGWTIGIYYDGSFISVPKVQAVISDGKASITGMGSYESAENLASTIRIGGLDVS
                     LTELRANVVGAQLGASAIHTSKIAAIIGLILIVLFMVIVFRILGVAASMALGFYCCFMV
                     ILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEIAAGSAVDKAIKAGYSKALS
                     AILDGNITTLIAAGVLGLRGTGSVRGFAITLALGILVSMFTALVVTRGI"
     aSDomain        4265..4963
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_3_0004"
                     /evalue="1.20E-56"
                     /identifier="TIGR00916"
                     /label="ctg82_3"
                     /locus_tag="ctg82_3"
                     /protein_end="423"
                     /protein_start="190"
                     /score="189.9"
                     /tool="antismash"
                     /translation="LTSEGAKKFATATEAAYANGWTIGIYYDGSFISVPKVQAVISDGK
                     ASITGMGSYESAENLASTIRIGGLDVSLTELRANVVGAQLGASAIHTSKIAAIIGLILI
                     VLFMVIVFRILGVAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLV
                     FARIREEIAAGSAVDKAIKAGYSKALSAILDGNITTLIAAGVLGLRGTGSVRGFAITLA
                     LGILVSMFTAL"
     PFAM_domain     4478..4981
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_3_0003"
                     /evalue="4.30E-13"
                     /label="ctg82_3"
                     /locus_tag="ctg82_3"
                     /protein_end="429"
                     /protein_start="261"
                     /score="49.2"
                     /tool="antismash"
                     /translation="SLTELRANVVGAQLGASAIHTSKIAAIIGLILIVLFMVIVFRILG
                     VAASMALGFYCCFMVILLSAFDITLTLPGIAGIILSIGMAVDANVLVFARIREEIAAGS
                     AVDKAIKAGYSKALSAILDGNITTLIAAGVLGLRGTGSVRGFAITLALGILVSMFTALV
                     VTRGI"
     aSDomain        5156..5923
                     /aSDomain="TIGR00966"
                     /aSTool="tigrfam"
                     /description="3a0501s07: protein-export membrane protein
                     SecF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_3_0006"
                     /evalue="1.60E-59"
                     /identifier="TIGR00966"
                     /label="ctg82_3"
                     /locus_tag="ctg82_3"
                     /protein_end="743"
                     /protein_start="487"
                     /score="199.6"
                     /tool="antismash"
                     /translation="FNYSIDFVGGTATTVSFAEGQTPSVEDLENVIEPAVINAASTADA
                     NLKNLSISHQIVKDQNQVVLKTQTLSTDASQAVHELLTTTYGATDVTYNTISATISDEM
                     TSDASWATIIALILMLIYIYFRFRDIRFGASAIIALAHDAIMVIMCYAFTRLEVGSTFI
                     AVVLTIIGYSINDTIVTFDRIRENQHGIRSREQLKELVNESVNQTLTRSLFTSITTFIM
                     VLCLYVVGVQDIKTFALPLMVGVVSGTYSSICIA"
     aSDomain        5312..5914
                     /aSDomain="TIGR00916"
                     /aSTool="tigrfam"
                     /description="2A0604s01: protein-export membrane protein,
                     SecD/SecF family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_3_0005"
                     /evalue="5.00E-45"
                     /identifier="TIGR00916"
                     /label="ctg82_3"
                     /locus_tag="ctg82_3"
                     /protein_end="740"
                     /protein_start="539"
                     /score="151.8"
                     /tool="antismash"
                     /translation="SHQIVKDQNQVVLKTQTLSTDASQAVHELLTTTYGATDVTYNTIS
                     ATISDEMTSDASWATIIALILMLIYIYFRFRDIRFGASAIIALAHDAIMVIMCYAFTRL
                     EVGSTFIAVVLTIIGYSINDTIVTFDRIRENQHGIRSREQLKELVNESVNQTLTRSLFT
                     SITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTYSSI"
     PFAM_domain     5417..5950
                     /aSDomain="SecD_SecF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02355.18"
                     /description="Protein export membrane protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_3_0004"
                     /evalue="9.50E-55"
                     /label="ctg82_3"
                     /locus_tag="ctg82_3"
                     /protein_end="752"
                     /protein_start="574"
                     /score="185.0"
                     /tool="antismash"
                     /translation="ATDVTYNTISATISDEMTSDASWATIIALILMLIYIYFRFRDIRF
                     GASAIIALAHDAIMVIMCYAFTRLEVGSTFIAVVLTIIGYSINDTIVTFDRIRENQHGI
                     RSREQLKELVNESVNQTLTRSLFTSITTFIMVLCLYVVGVQDIKTFALPLMVGVVSGTY
                     SSICIASQLWFSMKK"
     CDS             6050..7870
                     /locus_tag="ctg82_4"
                     /transl_table=11
                     /translation="MAKWMIAAKKADFDAIAKQFNISPITARLLRNRDLTTTEDIQRYL
                     YGGREDLRDAHDLTDIDKAADIMKDRIDAGSKIRIIGDYDVDGICSSYILWAGLTFAAR
                     GSKAENAVNSQTDYRLPDRIIDGYGLNDRLVHEAKDDNIDTIITCDNGIAAYDQVQLAK
                     DLGLTVVVTDHHEVPISKDGDEEKQILPPADAVVDPKRHDCNVKFKEICGGVVAYKFLQ
                     VLFEKYEEAGWKYSKSEIDEFFNEMLEFAALSTVCDVMPIEDENRVLVREGLKQMENSG
                     NLGLSSLINVNGLQGSKMTAYHLGFVIGPCLNATGRLDRAMRGLDLLTSTSEMAAVNIA
                     GDLKSLNDSRKTMTQLGVDQATAEMDKCVKDLPKVIVLYQPDLHESIAGIVAGRVREKY
                     SRPTIILTNAHDGVKGSGRSTENYDMFRALSECKDLFTKFGGHKMAAGLSLPTENVDEL
                     RRRLNENCDLTEEDFVEIKHLDMVLPLQYLSLSLIREFDILEPYGNGNDKPSFACRDIR
                     IKSGRIMGKNRNCGKYRIADANGREYEMVYFGNMEKWHDFLTDRYGNAIIDALYNNSVN
                     EDIVLNIAYYPDINSWQGRESLQIVMTDFC"
     aSDomain        6116..7861
                     /aSDomain="TIGR00644"
                     /aSTool="tigrfam"
                     /description="recJ: single-stranded-DNA-specific
                     exonuclease RecJ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_4_0007"
                     /evalue="1.50E-140"
                     /identifier="TIGR00644"
                     /label="ctg82_4"
                     /locus_tag="ctg82_4"
                     /protein_end="604"
                     /protein_start="22"
                     /score="467.0"
                     /tool="antismash"
                     /translation="SPITARLLRNRDLTTTEDIQRYLYGGREDLRDAHDLTDIDKAADI
                     MKDRIDAGSKIRIIGDYDVDGICSSYILWAGLTFAARGSKAENAVNSQTDYRLPDRIID
                     GYGLNDRLVHEAKDDNIDTIITCDNGIAAYDQVQLAKDLGLTVVVTDHHEVPISKDGDE
                     EKQILPPADAVVDPKRHDCNVKFKEICGGVVAYKFLQVLFEKYEEAGWKYSKSEIDEFF
                     NEMLEFAALSTVCDVMPIEDENRVLVREGLKQMENSGNLGLSSLINVNGLQGSKMTAYH
                     LGFVIGPCLNATGRLDRAMRGLDLLTSTSEMAAVNIAGDLKSLNDSRKTMTQLGVDQAT
                     AEMDKCVKDLPKVIVLYQPDLHESIAGIVAGRVREKYSRPTIILTNAHDGVKGSGRSTE
                     NYDMFRALSECKDLFTKFGGHKMAAGLSLPTENVDELRRRLNENCDLTEEDFVEIKHLD
                     MVLPLQYLSLSLIREFDILEPYGNGNDKPSFACRDIRIKSGRIMGKNRNCGKYRIADAN
                     GREYEMVYFGNMEKWHDFLTDRYGNAIIDALYNNSVNEDIVLNIAYYPDINSWQGRESL
                     QIVMTD"
     PFAM_domain     6278..6736
                     /aSDomain="DHH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01368.22"
                     /description="DHH family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_4_0005"
                     /evalue="3.10E-17"
                     /label="ctg82_4"
                     /locus_tag="ctg82_4"
                     /protein_end="229"
                     /protein_start="76"
                     /score="63.1"
                     /tool="antismash"
                     /translation="KIRIIGDYDVDGICSSYILWAGLTFAARGSKAENAVNSQTDYRLP
                     DRIIDGYGLNDRLVHEAKDDNIDTIITCDNGIAAYDQVQLAKDLGLTVVVTDHHEVPIS
                     KDGDEEKQILPPADAVVDPKRHDCNVKFKEICGGVVAYKFLQVLFEKYE"
     PFAM_domain     7085..7444
                     /aSDomain="DHHA1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02272.21"
                     /description="DHHA1 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_4_0006"
                     /evalue="6.90E-19"
                     /label="ctg82_4"
                     /locus_tag="ctg82_4"
                     /protein_end="465"
                     /protein_start="345"
                     /score="68.7"
                     /tool="antismash"
                     /translation="LNDSRKTMTQLGVDQATAEMDKCVKDLPKVIVLYQPDLHESIAGI
                     VAGRVREKYSRPTIILTNAHDGVKGSGRSTENYDMFRALSECKDLFTKFGGHKMAAGLS
                     LPTENVDELRRRLNEN"
     PFAM_domain     7487..7861
                     /aSDomain="RecJ_OB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17768.3"
                     /description="RecJ OB domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_4_0007"
                     /evalue="2.10E-26"
                     /label="ctg82_4"
                     /locus_tag="ctg82_4"
                     /protein_end="604"
                     /protein_start="479"
                     /score="92.4"
                     /tool="antismash"
                     /translation="DMVLPLQYLSLSLIREFDILEPYGNGNDKPSFACRDIRIKSGRIM
                     GKNRNCGKYRIADANGREYEMVYFGNMEKWHDFLTDRYGNAIIDALYNNSVNEDIVLNI
                     AYYPDINSWQGRESLQIVMTD"
     CDS             8004..9491
                     /locus_tag="ctg82_5"
                     /transl_table=11
                     /translation="MKLTTLLEKIDYKAFEGNTGNEADISNVEIKSVVNNSKKIEEGCF
                     FMCIKGANFDGHSVAAQAAEQKAAAILVQDDVTLPEDCKMPVIRVEDTRYAMAFVSAAW
                     FGNPAQSLKTIGITGTKGKTTTTYLIKSMLENAGHKVGLIGTIEVVIGDKHIPAKNTTP
                     ESYDLQEYMRQMVDEGCDSLVMEVSSQALMQHRSQGFVYDLGIFTNIEPDHIGPDEHKD
                     FDDYMHCKGLLFKQCKVGIANADDEHMEQVLEGHTCKLETFGFSDKADIKAVNLAYIRK
                     PGQLGVFFDTEGLIELHAEVRTPGKFSVYNALCAIAVARHFGCTDEEIAEALKNAKVKG
                     RIEMVKVSDDFTLMIDYAHNAMALKSLLSTLKDYRPNRLVCLFGCGGNRSKLRRYEMGE
                     VSGKLADLTIITSDNPRFEEPLDIIHDIEIGMKKTDGKYVEIPDRKEAIAYAIDNAQKG
                     DIIILAGKGHEDYQEIKGVKYPMDERDLIADIMKERM"
     aSDomain        8085..9476
                     /aSDomain="TIGR01085"
                     /aSTool="tigrfam"
                     /description="murE: UDP-N-acetylmuramyl-tripeptide
                     synthetase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_5_0008"
                     /evalue="2.60E-132"
                     /identifier="TIGR01085"
                     /label="ctg82_5"
                     /locus_tag="ctg82_5"
                     /protein_end="491"
                     /protein_start="27"
                     /score="440.0"
                     /tool="antismash"
                     /translation="VEIKSVVNNSKKIEEGCFFMCIKGANFDGHSVAAQAAEQKAAAIL
                     VQDDVTLPEDCKMPVIRVEDTRYAMAFVSAAWFGNPAQSLKTIGITGTKGKTTTTYLIK
                     SMLENAGHKVGLIGTIEVVIGDKHIPAKNTTPESYDLQEYMRQMVDEGCDSLVMEVSSQ
                     ALMQHRSQGFVYDLGIFTNIEPDHIGPDEHKDFDDYMHCKGLLFKQCKVGIANADDEHM
                     EQVLEGHTCKLETFGFSDKADIKAVNLAYIRKPGQLGVFFDTEGLIELHAEVRTPGKFS
                     VYNALCAIAVARHFGCTDEEIAEALKNAKVKGRIEMVKVSDDFTLMIDYAHNAMALKSL
                     LSTLKDYRPNRLVCLFGCGGNRSKLRRYEMGEVSGKLADLTIITSDNPRFEEPLDIIHD
                     IEIGMKKTDGKYVEIPDRKEAIAYAIDNAQKGDIIILAGKGHEDYQEIKGVKYPMDERD
                     LIADIM"
     PFAM_domain     8091..8309
                     /aSDomain="Mur_ligase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01225.27"
                     /description="Mur ligase family, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_5_0008"
                     /evalue="2.40E-06"
                     /label="ctg82_5"
                     /locus_tag="ctg82_5"
                     /protein_end="102"
                     /protein_start="29"
                     /score="27.9"
                     /tool="antismash"
                     /translation="IKSVVNNSKKIEEGCFFMCIKGANFDGHSVAAQAAEQKAAAILVQ
                     DDVTLPEDCKMPVIRVEDTRYAMAFVSA"
     PFAM_domain     8352..8960
                     /aSDomain="Mur_ligase_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08245.14"
                     /description="Mur ligase middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_5_0009"
                     /evalue="4.90E-48"
                     /label="ctg82_5"
                     /locus_tag="ctg82_5"
                     /protein_end="319"
                     /protein_start="116"
                     /score="163.8"
                     /tool="antismash"
                     /translation="ITGTKGKTTTTYLIKSMLENAGHKVGLIGTIEVVIGDKHIPAKNT
                     TPESYDLQEYMRQMVDEGCDSLVMEVSSQALMQHRSQGFVYDLGIFTNIEPDHIGPDEH
                     KDFDDYMHCKGLLFKQCKVGIANADDEHMEQVLEGHTCKLETFGFSDKADIKAVNLAYI
                     RKPGQLGVFFDTEGLIELHAEVRTPGKFSVYNALCAIAVA"
     PFAM_domain     9015..9269
                     /aSDomain="Mur_ligase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02875.23"
                     /description="Mur ligase family, glutamate ligase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_5_0010"
                     /evalue="6.30E-18"
                     /label="ctg82_5"
                     /locus_tag="ctg82_5"
                     /protein_end="422"
                     /protein_start="337"
                     /score="64.9"
                     /tool="antismash"
                     /translation="VKGRIEMVKVSDDFTLMIDYAHNAMALKSLLSTLKDYRPNRLVCL
                     FGCGGNRSKLRRYEMGEVSGKLADLTIITSDNPRFEEPLD"
     CDS             9591..9680
                     /locus_tag="ctg82_6"
                     /transl_table=11
                     /translation="MDSNICENAVIKKINIKLYYEQERRGRVI"
     CDS             9947..12340
                     /locus_tag="ctg82_7"
                     /transl_table=11
                     /translation="MDNTTESNIYAKIIIDISHEQVDRTFCYKVPERLIGSVDVGSCVQ
                     VPFGRGNKVRTGYVMELTDTADFDPAKIKEIVSIATENLPAEDIFIKLAAWMKQRYGST
                     MYAALKTVLPAHKKQTTLKHKFISLRMAQREATEYLYECRQKNRKAQERLLAELLTEPE
                     ERIPYELVTGKLNISAATIRSLKEKCVINVTEEEYYRNPVNISAGATRRLNLSDEQQHV
                     VDKVISDFDANIKKTYLVHGITGSGKTEVYIRMIEEIIARGKQAIVLIPEISLTYQTLM
                     RFYRHFGERVSVMNSTLSPGEKYDQFERARNGQLDIIIGPRSALFTPFPNLGLIIIDEE
                     HEPAYKSEQMPKYHARETAITLAKLVKDGASVVLGSATPSLEAYYRAVSGEYELFELTK
                     RLTGGTLPEVECVDLRDELRSGNRSIFSRSLQEAIEDRLQKHEQLMLFINRRGLAGFVS
                     CRSCGHVFKCPHCDVSLSEHRGGKLVCHYCGYSEPVTRICPECGSKYVSAFRAGTEQIE
                     KEVLKNWPHARVLRMDADTTKTKDSYQKILSAFSNEEADILIGTQMIVKGHDFPKVTLV
                     GVLAADMSLYANDYRAAERTFQLLTQAAGRAGRGELAGKVIVQSYQPDHYAIQTAARQD
                     YGAFYDEEIAYRRLLAYPPVAHMMAVQITSKSEEAGITFSNKLRTILEQPVVPFLDLDG
                     SSYSFRSDNGRGNSNSNDISVSPSAYVRGSLMESEKPVIIGPAAANISKINDVFRFVIY
                     VKSQDYAILTKMKDKIERYTARLIEAGQYRGYSVQFDFDPINGF"
     PFAM_domain     9980..10288
                     /aSDomain="PriA_3primeBD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17764.3"
                     /description="3'DNA-binding domain (3'BD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_7_0011"
                     /evalue="1.40E-20"
                     /label="ctg82_7"
                     /locus_tag="ctg82_7"
                     /protein_end="114"
                     /protein_start="11"
                     /score="73.1"
                     /tool="antismash"
                     /translation="KIIIDISHEQVDRTFCYKVPERLIGSVDVGSCVQVPFGRGNKVRT
                     GYVMELTDTADFDPAKIKEIVSIATENLPAEDIFIKLAAWMKQRYGSTMYAALKTVLP"
     PFAM_domain     10583..11083
                     /aSDomain="ResIII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04851.17"
                     /description="Type III restriction enzyme, res subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_7_0012"
                     /evalue="8.00E-14"
                     /label="ctg82_7"
                     /locus_tag="ctg82_7"
                     /protein_end="379"
                     /protein_start="212"
                     /score="52.1"
                     /tool="antismash"
                     /translation="LNLSDEQQHVVDKVISDFDANIKKTYLVHGITGSGKTEVYIRMIE
                     EIIARGKQAIVLIPEISLTYQTLMRFYRHFGERVSVMNSTLSPGEKYDQFERARNGQLD
                     IIIGPRSALFTPFPNLGLIIIDEEHEPAYKSEQMPKYHARETAITLAKLVKDGASVVLG
                     SATP"
     aSDomain        10661..12001
                     /aSDomain="TIGR00595"
                     /aSTool="tigrfam"
                     /description="priA: primosomal protein N'"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg82_7_0009"
                     /evalue="2.50E-178"
                     /identifier="TIGR00595"
                     /label="ctg82_7"
                     /locus_tag="ctg82_7"
                     /protein_end="685"
                     /protein_start="238"
                     /score="591.7"
                     /tool="antismash"
                     /translation="LVHGITGSGKTEVYIRMIEEIIARGKQAIVLIPEISLTYQTLMRF
                     YRHFGERVSVMNSTLSPGEKYDQFERARNGQLDIIIGPRSALFTPFPNLGLIIIDEEHE
                     PAYKSEQMPKYHARETAITLAKLVKDGASVVLGSATPSLEAYYRAVSGEYELFELTKRL
                     TGGTLPEVECVDLRDELRSGNRSIFSRSLQEAIEDRLQKHEQLMLFINRRGLAGFVSCR
                     SCGHVFKCPHCDVSLSEHRGGKLVCHYCGYSEPVTRICPECGSKYVSAFRAGTEQIEKE
                     VLKNWPHARVLRMDADTTKTKDSYQKILSAFSNEEADILIGTQMIVKGHDFPKVTLVGV
                     LAADMSLYANDYRAAERTFQLLTQAAGRAGRGELAGKVIVQSYQPDHYAIQTAARQDYG
                     AFYDEEIAYRRLLAYPPVAHMMAVQITSKSEEAGITFSNKLRTILEQP"
     PFAM_domain     11348..11425
                     /aSDomain="PriA_CRR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18319.3"
                     /description="PriA DNA helicase Cys-rich region (CRR)
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_7_0013"
                     /evalue="8.40E-10"
                     /label="ctg82_7"
                     /locus_tag="ctg82_7"
                     /protein_end="493"
                     /protein_start="467"
                     /score="38.5"
                     /tool="antismash"
                     /translation="CPHCDVSLSEHRGGKLVCHYCGYSEP"
     PFAM_domain     11492..11776
                     /aSDomain="Helicase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00271.33"
                     /description="Helicase conserved C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_7_0014"
                     /evalue="1.20E-07"
                     /label="ctg82_7"
                     /locus_tag="ctg82_7"
                     /protein_end="610"
                     /protein_start="515"
                     /score="32.2"
                     /tool="antismash"
                     /translation="IEKEVLKNWPHARVLRMDADTTKTKDSYQKILSAFSNEEADILIG
                     TQMIVKGHDFPKVTLVGVLAADMSLYANDYRAAERTFQLLTQAAGRAGRG"
     PFAM_domain     12131..12325
                     /aSDomain="PriA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18074.3"
                     /description="Primosomal protein N C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg82_7_0015"
                     /evalue="3.10E-06"
                     /label="ctg82_7"
                     /locus_tag="ctg82_7"
                     /protein_end="793"
                     /protein_start="728"
                     /score="28.0"
                     /tool="antismash"
                     /translation="EKPVIIGPAAANISKINDVFRFVIYVKSQDYAILTKMKDKIERYT
                     ARLIEAGQYRGYSVQFDFDP"
ORIGIN
        1 gagctgggtt cagaacgtcg tgagacagtt cggtccctat ccggcgcggg cgtaggatat
       61 ctgagaggag ctgtccttag tacgagagga ccgggatgga cggaccgctg gtgtatctgc
      121 tgcgaaggca atcgcataag gcagggtagc caagtctggc agggataaac gctgaaggca
      181 tctaagcgtg aagcccccct caagatgaga tatccccacg caagtggtaa gaccccttgg
      241 agagtacgag gttgataggc acaaggtgta agagtggtaa cattctcagc tgatgtgtac
      301 taataggtcg aggacttaac caaaaagtca agaaagtttg gaaattcagt gttcggtttt
      361 gaaggaataa gttcagctct atgcttatcg catagagctt ttttgttgca caagaccggc
      421 aagcgaatgg atgcttgcat acaaattcat ttgccggttg taagaacatg gagcacgaag
      481 tgcggaatgt tcgtgtgcga aatcgagtag gagtcagcct actcgattgt tcaaaagcta
      541 cattttaatc ggtttctatg gtgtaactta ttggttggaa atatactaat taaatacatt
      601 gtaataatag ttgtattaaa gacgattagt agcattattt tatgcttaaa tctgccattt
      661 caaagcaaaa atcttttaca cagtaattaa actatggtat actattctaa cgtatgagat
      721 tatctcattt taattaaccg ggaggaaatg acatgaagca cgttaagaca cttgctacaa
      781 gaaatcttaa agagtctatg aaaaagggcg gatgtggcga atgccagaca tcttgtcagt
      841 ctgcttgcaa gacatcttgc acagttggaa atcagagctg tgagcagctt gcaaagaact
      901 aaccttttgt ctttataact ggtttagatt ctgatgtatc cctttagaga tcaatcggat
      961 cccagtaatt cgtaaattat cctaagggat ttatgagcat gtatagcgat attccctgta
     1021 tatgataacg ggcatattgc tatacttgtt ttctgtgttt ataaaatatt ttttatattt
     1081 ttactggtag atagagagtt acagatttaa tggttcatat atttaagaat aatggttata
     1141 acatcgtatt agacgtgaac agtggcagcg ttcatgttgt agatgaaata gtttatgatc
     1201 tcattccttc agtggaagag atccttacag gaatgtttgg tactgcacag attcctgaaa
     1261 atgaagaaga tagtgagata agtaaagagc ttttaagaaa agttacagat gcagttgttg
     1321 ctaaaggaac atcttatcct gaaagtgaag tagaagaagc agttgaagaa atcttatcat
     1381 tacgtcaggc tggtctcttg tatacagatg atatatatga gaattatgta gaagagttca
     1441 agaccagaga tacagttatt aaggcgttgt gtttgaatat agcgcatgat tgcaatcttc
     1501 gttgcaaata ttgttttgca gatgaaggtg agtatcatgg acgcaaagcc atgatgactt
     1561 ttgaagttgg taaggcagca cttgatttcc ttgttaagaa ctcaggcgat cgtcataacc
     1621 ttgaagttga cttctttggt ggcgagcctt taatgaactg ggaagttgtt aagcagatag
     1681 ttgagtatgg tcgtagcatt gagaaagagg ctggtaagaa tttccgcttt acgattacga
     1741 ctaatggtac tcttcttaca aaagagatac ttgattattg caataaagaa atgggcaata
     1801 tagtcctttc aattgacgga cgtaaggaag tcaatgacaa gatgagacct aatgcagctg
     1861 gtcatggaat gtatgatatg atcgttccta aatatcttga agttgcaaag tcaagacatc
     1921 agctcagata ttttgtaagg ggtacattta ctcataacaa tcttgatttt gctgaagatg
     1981 ttaagcacct tgcagatctt ggcttcaagc agatatcaat ggagcctgta gttgcaaagc
     2041 cggaagactg gtatgcaatc aaggaagaag atcttccaca gcttaaggaa gaatacgata
     2101 agcttgcaaa gatttacctt cagtatagaa aagaaggtaa aggattcaac ttcttccact
     2161 tcaatataga tctttcaggc ggcccttgcg ttgcaaagcg tctttcagga tgcggaagcg
     2221 gatgtgagta tgtaggcgtt actccttggg gagatattta tccatgtcat cagtttgtag
     2281 gtaacgaaga ctttattatg ggtaatgtct ttgaaggaat caagcgtaca gacattcagc
     2341 agcagttcaa ggagagtaat gtatactcaa gacctgaatg ccagaagtgt tttgctagat
     2401 actattgtag cggtggatgc agcgccaacg catacaattt caatggtaat atcaacaccg
     2461 tctataaaga aggttgtgaa ctacaacgta agcgcattga atgtgcgatt atgataaaag
     2521 cggcacttgc tgaagaagca gaagttaaga atgctggtta acggaggctt tacatgaaaa
     2581 aattcaagcc agtaattctg ataccagtac ttttgatatt acttgcagta ctttgttttt
     2641 atgtttttca aggtttgact gattataaag aaaattcttc cgaagatgat gactgctcag
     2701 agtatgaaga tggtattcat gttacctatg aaatcaccta tttaaatggc gatattccta
     2761 ctgatcagga tatggaagat ataaaagaat tgctaacaga acgtattgca tctgaagttg
     2821 aaccagaagg atcagatgaa gattctgaga gtgaagataa aaaatcagac ctatccgaga
     2881 attttgaaag tatacttcca ggaaataaag acgcagtata taaagtgaat tgggtcggaa
     2941 gtaatcgcat tgaaatatat agtcaagatg ttgcagatgt tgttatagaa agaataacta
     3001 ctactcctga gttgtatttt attcgtgaat ataatgatac aggatcagct aactactatg
     3061 atccttatgg gatgggatat gcagtattca tggagctttc agaaggtgta acaatagatt
     3121 ctcttaagga gagtggtgat attgttttat cagctgaaga tatagctgat gcacaggctg
     3181 gaattgataa atcaggtgca ggctcagaat atattgtaga gcttacattt acatcagaag
     3241 gtgctgagaa atttgccgca gctacagaat cggcttatgc taatggcgag actatcggta
     3301 tttattatga tggagccttt ataagtgttc cgagagtaca agcggttatc actgatggta
     3361 aggcttccat tactggtatg ggatcatatg aaagtgctga gatgcttgct aagaatattc
     3421 gtcttggtaa tttgaagctt tccgaggttg aaactgattc aagcgataca gttactgata
     3481 ctgaaaacag tattgataca aatataataa ttgctattat aggtatcata gtaatagtat
     3541 taatactctt tgtattttta gtacttggca tttataaagc cattgtacgt aaatgatttc
     3601 taagacgtaa gcgcattgaa tgtgcgatta tgataaaagc ggcacttgct gaagaagcag
     3661 atgtccaaaa cgtgggttaa cggaggttat aaaaatgaag aagttaaagc aggtactgcc
     3721 tttagttgtt gtattggctg tactggtagg attgttctat gttgcttggc atggagtggg
     3781 agaaacacaa gatggctcta tgcacgacat aaacttcggt cttgatcttg caggtggtgt
     3841 cagcatcact tatcaggtag ctggtgagaa tggcggaaca ccaacaactc aggagatgga
     3901 tgacacagta tctaagctct ctaagcgtgt tgcttccgag cttaatacaa cagaagcttc
     3961 tgtttataag gaaggttcag atcgtatcac agtagaaatt cctggtgcta cagatgagat
     4021 tttcgaaact ctttcaacac ctggtaatct gtatttcatt cgtgaatata atgatgcagg
     4081 ttcagctaac tactatgatc cttatggaat gggatattct gcattctata tgcttgcaga
     4141 tggtgtgaca attgaatcac ttcaggcaag tggagacatc gttctttctg gtgaagatat
     4201 tgctgatgcg caggctggaa ttgataattc tggtacaggt tcagagtata tcgtagagct
     4261 tacacttaca tcagaaggtg ctaagaagtt tgctacagct acagaagcag cttatgctaa
     4321 tggctggaca atcggtattt actatgatgg atctttcatc agtgttccta aagttcaggc
     4381 tgtaatttca gatggtaagg catcaattac aggtatgggt tcttatgaat ctgctgaaaa
     4441 ccttgcatct acaattcgta tcggtggact tgatgtatct cttacagaac ttcgtgcaaa
     4501 cgttgtagga gctcagcttg gtgcaagtgc tattcataca agtaagattg cagctatcat
     4561 tggtcttata cttatcgttc tgttcatggt catcgttttc agaatacttg gtgtagcagc
     4621 atctatggcg cttggcttct actgctgctt tatggtaata cttctttcag catttgatat
     4681 aacacttaca cttcctggta ttgcaggtat catcctttca atcggtatgg cggttgatgc
     4741 taacgttctt gtatttgcac gtatcagaga agagattgca gctggatcag ctgtagataa
     4801 agctattaaa gccggatatt caaaggctct ttcagctatc cttgatggta acatcacaac
     4861 acttattgct gccggtgttc ttggacttcg tggaacaggt tcagtaagag gctttgctat
     4921 tactcttgcg cttggtattc ttgtttccat gtttacagca cttgttgtta caagaggtat
     4981 ttcttcaatc cttttcaatc ttggattcaa ggctgaaggc ttctatggta aagctaaaga
     5041 tcctaagaag atcgattttg tatcaaagag aaatatcttc tatgcaattt cagttatcat
     5101 aatggttgct ggtattggaa catgtgtatt taaccacgtt gctggtaatc atgcatttaa
     5161 ctattcaatt gatttcgtag gtggtacagc tacaacagta tcatttgcag aaggtcagac
     5221 tccttcagtt gaagaccttg aaaacgtaat cgagcctgct gttataaatg cagcatctac
     5281 tgctgatgct aatcttaaga atctttcaat ttctcaccag attgttaagg atcagaatca
     5341 ggttgtatta aagactcaaa ctctttcaac agatgcttca caggctgttc atgaacttct
     5401 tacaacaact tatggtgcta cagatgtaac atataacaca atcagtgcta ctatcagtga
     5461 tgagatgaca agtgatgcaa gctgggctac aattatcgca ctcatcctta tgcttatcta
     5521 tatctatttc agatttagag atatccgctt tggtgctagt gctatcatcg ctcttgctca
     5581 tgatgctatt atggttatca tgtgctacgc atttacaaga cttgaggttg gaagcacatt
     5641 catcgctgta gtacttacaa tcattggtta ctcaatcaac gatactatcg ttacattcga
     5701 ccgtattcgt gagaatcagc atggtattcg ttcaagagag cagcttaaag agcttgttaa
     5761 tgagtcagtt aaccagactc ttacaagatc actctttaca tctatcacaa cattcatcat
     5821 ggtactttgt ctgtatgttg taggtgttca ggatatcaag acttttgcac ttcctcttat
     5881 ggttggtgta gtaagtggta catattcttc tatctgcata gcatcacagc tttggttctc
     5941 aatgaagaag aaaagtgtag agaaagctta acctatacta aaaatattaa gactgcagga
     6001 agtttaaaac tttctgcagt ttttttcttt aaaaaggata tataagttaa tggcaaaatg
     6061 gatgatagca gccaagaagg ctgattttga cgcaatagca aagcagttta atataagccc
     6121 tattacggcc aggttattac gaaacagaga ccttacaaca actgaagata ttcagagata
     6181 tctctatgga ggtcgtgaag acttaagaga tgctcatgac ctgactgata tagataaagc
     6241 tgctgacata atgaaggaca ggattgacgc cggaagcaag ataaggatca taggtgacta
     6301 tgacgttgat ggaatatgct catcttacat tctttgggca ggactaacat ttgcagcaag
     6361 gggatctaaa gcagaaaatg cagttaattc acagactgac tataggcttc ccgatagaat
     6421 aatagatgga tatggtctta atgacaggct tgttcatgag gctaaagatg acaatatcga
     6481 tactataatt acttgcgata atggtatagc agcctatgat caggttcagc ttgccaaaga
     6541 tctggggctt acagtagttg ttacagatca ccacgaagtt ccgatttcta aagacggtga
     6601 tgaggaaaaa cagatcctgc ctcctgcaga tgcagtagtt gatcctaagc gtcatgactg
     6661 taatgtgaag ttcaaggaga tatgcggagg agttgtagca tataagttcc ttcaggttct
     6721 ttttgaaaaa tatgaagaag caggctggaa gtactcaaaa tctgaaatag atgaattctt
     6781 taatgaaatg cttgaatttg ctgccctgtc aacagtatgt gatgttatgc ctatcgaaga
     6841 tgagaacaga gttcttgtca gagaaggcct taagcagatg gagaattccg gtaatcttgg
     6901 acttagtagt cttattaatg ttaatggtct tcagggaagt aagatgactg cttatcacct
     6961 tggatttgtt ataggacctt gtcttaatgc tacaggaaga ctggaccgtg ctatgagggg
     7021 ccttgatctt cttacttcaa caagtgagat ggctgctgta aacatagcag gagaccttaa
     7081 atcgcttaat gatagcagaa agacaatgac tcagcttggc gtggatcagg caactgcaga
     7141 aatggataaa tgcgttaaag atcttcctaa agtcatagtt ctctatcagc ctgatcttca
     7201 tgaatcaata gcaggaatag tagctggaag agtacgagag aagtattcaa gacctacgat
     7261 catacttact aatgcacatg atggtgttaa gggaagtgga agatcgacag agaactacga
     7321 tatgttcaga gctttatctg agtgtaaaga tctttttaca aagtttggtg gtcataaaat
     7381 ggcggcaggt ttgtcacttc ctactgaaaa tgttgatgag ctgcgccgca ggcttaatga
     7441 aaactgtgat cttacagaag aagattttgt tgagatcaag caccttgata tggtactgcc
     7501 tcttcagtat ttaagccttt cgcttataag agagtttgat attcttgagc cgtatggtaa
     7561 tggcaacgat aagccatctt ttgcctgccg tgatatcagg atcaagtcag gacgaattat
     7621 gggcaagaac agaaactgcg gcaaatacag gattgctgat gcaaatggca gagaatacga
     7681 aatggtctat tttggaaata tggaaaaatg gcacgatttc ctaacagacc gatatggaaa
     7741 tgccataata gatgcgttat ataataatag tgtaaatgaa gacattgttc tgaatattgc
     7801 ttactatccg gatattaact catggcaggg cagagagagc ctccagatag taatgactga
     7861 tttttgttga aatcatcaga ttataactgt aatgatgtag ataaaatcaa gttatggaat
     7921 aatgatcagg gccaggatat aaagaataaa tgtatattat ttctttttat ataactaagt
     7981 cataaaaata aggagataca catatgaagc ttacaacttt gcttgagaaa atcgattaca
     8041 aagccttcga gggaaatacc ggtaacgaag ctgatatttc aaatgttgag atcaagtcag
     8101 tagttaacaa ttccaagaaa attgaagaag gctgcttttt tatgtgtatt aaaggagcta
     8161 attttgatgg ccatagcgta gcagcacagg cagctgagca gaaagctgca gcaatcctcg
     8221 ttcaggatga tgtaactctt cctgaagact gcaagatgcc tgttatccgt gttgaggaca
     8281 caagatatgc aatggcattt gtatcagctg catggtttgg aaatcctgca cagagtctta
     8341 agacaatcgg cattacaggt actaagggta agacaacaac aacttatctt ataaagagca
     8401 tgcttgaaaa tgcaggacat aaggtaggtc ttatcggtac tatcgaagtt gttataggag
     8461 ataagcatat tcctgctaag aatacaacac ctgagtcata tgaccttcag gagtatatga
     8521 gacagatggt tgatgaaggc tgcgacagcc ttgttatgga agtatcttca caggcgctta
     8581 tgcagcatag aagccaggga tttgtatatg accttggtat ttttacaaac attgagcctg
     8641 atcacatcgg cccagatgaa cacaaggatt tcgacgacta tatgcactgc aagggtcttt
     8701 tgttcaaaca gtgtaaggtt ggtattgcaa atgctgatga cgagcacatg gaacaggttc
     8761 ttgagggaca tacatgtaag cttgagacat tcggcttctc tgacaaagct gatatcaaag
     8821 ctgtaaacct tgcttatatc agaaagcctg gtcagcttgg agtattcttt gacacagaag
     8881 gtcttattga gcttcatgca gaagtgcgta ctcctggtaa attttctgtt tacaatgccc
     8941 tttgcgctat cgctgtagca agacactttg gctgcacaga tgaagagatc gctgaggcgc
     9001 ttaagaatgc caaggttaag ggccgtatcg agatggtcaa ggtatcagac gacttcacac
     9061 ttatgatcga ctatgctcat aatgctatgg cacttaagag tcttctttca actcttaagg
     9121 attatcgtcc taaccgcctt gtatgtctct ttggctgtgg cggtaacaga tctaagcttc
     9181 gccgttatga gatgggtgaa gtaagtggta agcttgcaga tcttactatc atcacatcag
     9241 ataacccaag attcgaagag ccgcttgata tcatccatga catcgagatc ggtatgaaga
     9301 agactgatgg taagtatgtt gagatccctg atagaaaaga agctattgct tatgcgatcg
     9361 ataatgctca gaagggtgat atcatcatcc ttgcaggtaa aggtcatgaa gactatcagg
     9421 agatcaaggg tgttaagtat cctatggatg aaagagatct cattgcagat atcatgaaag
     9481 agcgcatgta aatcctatga attaagtccc ctggtggtaa tgcatgtttc taatattttg
     9541 agagacgata aaattattga ttaaccatta tttctaggga catttaagat atggatagta
     9601 atatatgcga aaatgcagtt atcaaaaaaa ttaatataaa actctattat gaacaagaaa
     9661 gaagagggcg ggtgatatga tcatcttgcc ccttttttct tacctcaaaa tcttcaactt
     9721 tctacgcaat atttttcatt agcgccgctt tctgatacaa ttgataaggt gttatgaact
     9781 gacatataaa taaatctatt tctgatcata tactgcgaat tgagaaaaag aataatctga
     9841 ttctttaatg ccggttttaa taaaactgtg ttttgggaaa agaataatct gattctctaa
     9901 cgctgtttta cataatttgc gagtttataa agacccgagg actaacatgg acaatactac
     9961 agaatctaat atatacgcca aaattatcat agatatatct cacgagcagg tggacagaac
    10021 tttctgctat aaagttcctg agcgccttat aggcagtgtc gatgttggaa gctgcgtgca
    10081 ggtgccattt ggacgaggca ataaggttag gaccggctac gtcatggagc ttacggatac
    10141 tgcggacttt gatcctgcga agatcaaaga gatcgtttct atcgcgactg agaatcttcc
    10201 ggcagaagat atttttataa agcttgctgc ctggatgaag caaagatacg gctctaccat
    10261 gtatgcagca cttaagacag tacttcctgc gcataagaaa cagacaacac ttaagcataa
    10321 gtttatatcc ttaaggatgg cgcagcgaga agctacagaa tatctctatg aatgcaggca
    10381 aaagaacagg aaggcgcagg aaaggcttct tgcagagctc ttaactgagc ctgaagaaag
    10441 gattccctat gagcttgtaa caggaaagct caatatttct gcggcaacca taagaagtct
    10501 taaggaaaag tgcgtgataa atgtcaccga agaagagtat tatcgtaacc ctgttaatat
    10561 aagtgcgggt gcaaccagga ggcttaacct ttctgatgag cagcagcacg tagttgataa
    10621 ggtcatcagc gactttgatg cgaatataaa aaagacttat cttgtgcacg gcataacagg
    10681 aagcggtaag actgaagttt atatccgcat gatagaagag ataatagcaa ggggcaaaca
    10741 ggctatagtc cttatccctg agatatcttt gacctatcag acccttatgc gtttctaccg
    10801 ccactttgga gagcgagtat cagtaatgaa ttcaactctt tctcccgggg aaaaatatga
    10861 tcagtttgaa agggcaagaa atggccagct tgacataata atcggcccta ggtcagctct
    10921 ttttacacca tttccaaatc ttggacttat aataatagat gaggagcatg agcctgccta
    10981 taaatctgag cagatgccca agtatcatgc aagagagaca gctattacac ttgcaaaact
    11041 ggtaaaagac ggagcaagcg tggttttagg aagtgcgacc ccttctcttg aagcctatta
    11101 cagggctgta tcaggtgaat acgaactctt tgagcttacc aagagactta caggcggaac
    11161 attgccggaa gttgaatgcg tagatctaag agacgagctt agaagcggca acagatctat
    11221 tttttcaaga agtcttcagg aagcaatcga ggataggctt caaaagcacg agcagcttat
    11281 gctctttata aacagaagag gacttgcagg attcgtatca tgcagaagct gcggacatgt
    11341 atttaagtgc cctcactgcg atgtatctct atcggagcat agaggcggca agcttgtatg
    11401 ccactactgc ggatattcag agcctgtcac aagaatatgt cctgagtgcg gatccaagta
    11461 tgtttcagcc tttagggcag gaacagagca gatagaaaaa gaagttctta agaactggcc
    11521 acatgcaaga gtcctcagga tggatgcaga taccaccaag actaaggaca gctaccagaa
    11581 gatattgtct gctttttcca acgaagaagc cgatatactg ataggaacgc agatgatagt
    11641 taagggccac gatttcccta aggttacgct tgtgggagtt ttggctgcgg atatgtcact
    11701 ttatgctaat gactacaggg cggcagagcg aaccttccag cttctgacgc aggcagcagg
    11761 aagagcagga agaggagaac ttgccggcaa agtaatagta caaagctatc agcctgatca
    11821 ctatgcgatc cagaccgctg caaggcagga ttatggcgct ttttacgatg aagagattgc
    11881 ctacagaagg cttctggcgt accctcctgt tgcgcacatg atggcagttc agatcacttc
    11941 aaaaagtgaa gaagcaggaa taactttttc caataaattg aggactattt tagaacagcc
    12001 tgtagttcct tttctggatc ttgatggtag cagttatagc tttcgcagtg acaatggaag
    12061 aggtaattct aacagtaatg atataagcgt atctccctca gcttatgtaa gaggaagcct
    12121 tatggagagt gaaaagccgg ttatcatcgg tccggcagct gcgaatatat caaaaattaa
    12181 tgatgttttc agatttgtta tatatgttaa gtcgcaggat tatgctatat taactaagat
    12241 gaaagataaa attgaacggt ataccgccag actcatagaa gctggacaat accgaggata
    12301 ttcggtacaa tttgattttg accctataaa cggtttttga taatgataat tgatagggat
    12361 ctacatgttc tgctattgat cagtctattg attggctgat tattgtataa atttataatg
    12421 aagtattaac ggaggttaat tatggctata agacagattc gtgaatatgg tgatgaagta
    12481 cttgcaaaaa agtgcaaacc tgtcaaagaa atgacagatt caatacagga acttatcgat
    12541 gatatgttcg aaacaatgta t
//
