GCF_000439895.1_atcc_33301_v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_ATMJ01000010 (original name was: NZ_ATMJ01000010.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	NRPS	1	36,536	enterobactin	NRP	12%

NZ_ATMJ01000021 (original name was: NZ_ATMJ01000021.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	redox-cofactor	69,003	87,339	lankacidin C	NRP + Polyketide	13%

NZ_ATMJ01000033 (original name was: NZ_ATMJ01000033.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	thiopeptide	92,716	114,879	O-antigen	Saccharide	14%

No secondary metabolite regions were found in these records:: NZ_ATMJ01000001 (original name was: NZ_ATMJ01000001.1); NZ_ATMJ01000002 (original name was: NZ_ATMJ01000002.1); NZ_ATMJ01000003 (original name was: NZ_ATMJ01000003.1); NZ_ATMJ01000004 (original name was: NZ_ATMJ01000004.1); NZ_ATMJ01000005 (original name was: NZ_ATMJ01000005.1); NZ_ATMJ01000006 (original name was: NZ_ATMJ01000006.1); NZ_ATMJ01000007 (original name was: NZ_ATMJ01000007.1); NZ_ATMJ01000008 (original name was: NZ_ATMJ01000008.1); NZ_ATMJ01000009 (original name was: NZ_ATMJ01000009.1); NZ_ATMJ01000011 (original name was: NZ_ATMJ01000011.1); NZ_ATMJ01000012 (original name was: NZ_ATMJ01000012.1); NZ_ATMJ01000013 (original name was: NZ_ATMJ01000013.1); NZ_ATMJ01000014 (original name was: NZ_ATMJ01000014.1); NZ_ATMJ01000015 (original name was: NZ_ATMJ01000015.1); NZ_ATMJ01000016 (original name was: NZ_ATMJ01000016.1); NZ_ATMJ01000017 (original name was: NZ_ATMJ01000017.1); NZ_ATMJ01000018 (original name was: NZ_ATMJ01000018.1); NZ_ATMJ01000019 (original name was: NZ_ATMJ01000019.1); NZ_ATMJ01000020 (original name was: NZ_ATMJ01000020.1); NZ_ATMJ01000022 (original name was: NZ_ATMJ01000022.1); NZ_ATMJ01000023 (original name was: NZ_ATMJ01000023.1); NZ_ATMJ01000024 (original name was: NZ_ATMJ01000024.1); NZ_ATMJ01000025 (original name was: NZ_ATMJ01000025.1); NZ_ATMJ01000026 (original name was: NZ_ATMJ01000026.1); NZ_ATMJ01000027 (original name was: NZ_ATMJ01000027.1); NZ_ATMJ01000028 (original name was: NZ_ATMJ01000028.1); NZ_ATMJ01000029 (original name was: NZ_ATMJ01000029.1); NZ_ATMJ01000030 (original name was: NZ_ATMJ01000030.1); NZ_ATMJ01000031 (original name was: NZ_ATMJ01000031.1); NZ_ATMJ01000032 (original name was: NZ_ATMJ01000032.1); NZ_ATMJ01000034 (original name was: NZ_ATMJ01000034.1); NZ_ATMJ01000035 (original name was: NZ_ATMJ01000035.1); NZ_ATMJ01000036 (original name was: NZ_ATMJ01000036.1); NZ_ATMJ01000037 (original name was: NZ_ATMJ01000037.1); NZ_ATMJ01000038 (original name was: NZ_ATMJ01000038.1); NZ_ATMJ01000039 (original name was: NZ_ATMJ01000039.1); NZ_ATMJ01000040 (original name was: NZ_ATMJ01000040.1); NZ_ATMJ01000041 (original name was: NZ_ATMJ01000041.1); NZ_ATMJ01000042 (original name was: NZ_ATMJ01000042.1); NZ_ATMJ01000043 (original name was: NZ_ATMJ01000043.1); NZ_ATMJ01000044 (original name was: NZ_ATMJ01000044.1); NZ_ATMJ01000045 (original name was: NZ_ATMJ01000045.1); NZ_ATMJ01000046 (original name was: NZ_ATMJ01000046.1); NZ_ATMJ01000047 (original name was: NZ_ATMJ01000047.1); NZ_ATMJ01000048 (original name was: NZ_ATMJ01000048.1); NZ_ATMJ01000049 (original name was: NZ_ATMJ01000049.1); NZ_ATMJ01000050 (original name was: NZ_ATMJ01000050.1); NZ_ATMJ01000051 (original name was: NZ_ATMJ01000051.1); NZ_ATMJ01000052 (original name was: NZ_ATMJ01000052.1); NZ_ATMJ01000053 (original name was: NZ_ATMJ01000053.1); NZ_ATMJ01000054 (original name was: NZ_ATMJ01000054.1); NZ_ATMJ01000055 (original name was: NZ_ATMJ01000055.1); NZ_ATMJ01000056 (original name was: NZ_ATMJ01000056.1); NZ_ATMJ01000057 (original name was: NZ_ATMJ01000057.1); NZ_ATMJ01000058 (original name was: NZ_ATMJ01000058.1); NZ_ATMJ01000059 (original name was: NZ_ATMJ01000059.1); NZ_ATMJ01000060 (original name was: NZ_ATMJ01000060.1); NZ_ATMJ01000061 (original name was: NZ_ATMJ01000061.1); NZ_ATMJ01000062 (original name was: NZ_ATMJ01000062.1); NZ_ATMJ01000063 (original name was: NZ_ATMJ01000063.1); NZ_ATMJ01000064 (original name was: NZ_ATMJ01000064.1); NZ_ATMJ01000065 (original name was: NZ_ATMJ01000065.1); NZ_ATMJ01000066 (original name was: NZ_ATMJ01000066.1); NZ_ATMJ01000067 (original name was: NZ_ATMJ01000067.1); NZ_ATMJ01000068 (original name was: NZ_ATMJ01000068.1); NZ_ATMJ01000069 (original name was: NZ_ATMJ01000069.1); NZ_ATMJ01000070 (original name was: NZ_ATMJ01000070.1); NZ_ATMJ01000071 (original name was: NZ_ATMJ01000071.1); NZ_ATMJ01000072 (original name was: NZ_ATMJ01000072.1); NZ_ATMJ01000073 (original name was: NZ_ATMJ01000073.1); NZ_ATMJ01000074 (original name was: NZ_ATMJ01000074.1); NZ_ATMJ01000075 (original name was: NZ_ATMJ01000075.1); NZ_ATMJ01000076 (original name was: NZ_ATMJ01000076.1); NZ_ATMJ01000077 (original name was: NZ_ATMJ01000077.1); NZ_ATMJ01000078 (original name was: NZ_ATMJ01000078.1); NZ_ATMJ01000079 (original name was: NZ_ATMJ01000079.1); NZ_ATMJ01000080 (original name was: NZ_ATMJ01000080.1); NZ_ATMJ01000081 (original name was: NZ_ATMJ01000081.1); NZ_ATMJ01000082 (original name was: NZ_ATMJ01000082.1); NZ_ATMJ01000083 (original name was: NZ_ATMJ01000083.1); NZ_ATMJ01000084 (original name was: NZ_ATMJ01000084.1); NZ_ATMJ01000085 (original name was: NZ_ATMJ01000085.1)

Compact view

c00010_NZ_ATMJ.. - Region 1 - NRPS

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Location: 1 - 36,536 nt. (total: 36,536 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.34	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.33	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.29	NRP	paenibactin	Paenibacillus elgii B69
BGC0000410.1	0.26	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131.1	0.23	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.23	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.23	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.23	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.23	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.67	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.62	NRP	paenibactin	Paenibacillus elgii B69
BGC0000410.1	0.59	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001833.1	0.57	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131.1	0.57	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.57	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.56	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.56	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.56	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 36536:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg10_9

Search NORINE for peptide: strict or relaxed

AMP-binding (33..438): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PMPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg10_15

Search NORINE for peptide: strict or relaxed

AMP-binding (465..868): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

c00021_NZ_ATMJ.. - Region 1 - redox-cofactor

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Location: 69,003 - 87,339 nt. (total: 18,337 nt) Show pHMM detection rules used

Region on contig edge.

redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000928.1	0.15	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.15	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001727.1	0.14	RiPP	paenilan	Paenibacillus polymyxa E681
BGC0000842.1	0.13	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0000906.1	0.13	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.13	Other	heme D1	Heliobacillus mobilis
BGC0000260.1	0.12	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0000700.1	0.12	Saccharide	istamycin	Streptomyces tenjimariensis
BGC0000668.1	0.11	Terpene, Alkaloid	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830
BGC0001701.1	0.11	RiPP	nisin O	Blautia obeum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000928.1	0.45	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.45	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001727.1	0.43	RiPP	paenilan	Paenibacillus polymyxa E681
BGC0000842.1	0.42	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0000906.1	0.42	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.41	Other	heme D1	Heliobacillus mobilis
BGC0000260.1	0.40	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0000700.1	0.40	Saccharide	istamycin	Streptomyces tenjimariensis
BGC0000668.1	0.38	Terpene, Alkaloid	12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole	Hapalosiphon welwitschii UTEX B 1830
BGC0001701.1	0.38	RiPP	nisin O	Blautia obeum

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

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c00033_NZ_ATMJ.. - Region 1 - thiopeptide

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Location: 92,716 - 114,879 nt. (total: 22,164 nt) Show pHMM detection rules used

Region on contig edge.

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Thiopeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.25	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.16	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000800.1	0.14	Saccharide	xanthan	Xanthomonas campestris
BGC0001285.1	0.07	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0002012.1	0.04	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001302.1	0.04	Other	lomofungin	Streptomyces lomondensis
BGC0001283.1	0.04	Polyketide	arsono-polyketide	Streptomyces lividans 1326

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.58	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.47	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000800.1	0.44	Saccharide	xanthan	Xanthomonas campestris
BGC0001285.1	0.29	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0002012.1	0.20	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001302.1	0.20	Other	lomofungin	Streptomyces lomondensis
BGC0001283.1	0.19	Polyketide	arsono-polyketide	Streptomyces lividans 1326

Similar known gene clusters

Thiopeptide predictions

No core peptides found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

Thiopeptides

Core peptide predictions

No core peptides found.