Select genomic region:
Overview
1.1
3.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_AUFP01000001 (original name was: NZ_AUFP01000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene | 58,778 | 106,336 | flexirubin | Polyketide | 13%

NZ_KE384540.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | RRE-containing | 262,064 | 282,336 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene | 58,778 | 106,336 | flexirubin | Polyketide | 13%
Region 3.1 | RRE-containing | 262,064 | 282,336 |

No secondary metabolite regions were found in these records:
  NZ_AUFP01000002 (original name was: NZ_AUFP01000002.1)
  NZ_AUFP01000005 (original name was: NZ_AUFP01000005.1)
  NZ_AUFP01000006 (original name was: NZ_AUFP01000006.1)
  NZ_AUFP01000007 (original name was: NZ_AUFP01000007.1)
  NZ_AUFP01000008 (original name was: NZ_AUFP01000008.1)
  NZ_AUFP01000009 (original name was: NZ_AUFP01000009.1)
  NZ_AUFP01000010 (original name was: NZ_AUFP01000010.1)
  NZ_AUFP01000011 (original name was: NZ_AUFP01000011.1)
  NZ_AUFP01000012 (original name was: NZ_AUFP01000012.1)
  NZ_AUFP01000013 (original name was: NZ_AUFP01000013.1)
  NZ_AUFP01000014 (original name was: NZ_AUFP01000014.1)
  NZ_KE384541.1
  NZ_AUFP01000017 (original name was: NZ_AUFP01000017.1)
  NZ_AUFP01000018 (original name was: NZ_AUFP01000018.1)
  NZ_KE384542.1
  NZ_AUFP01000021 (original name was: NZ_AUFP01000021.1)
  NZ_AUFP01000022 (original name was: NZ_AUFP01000022.1)
  NZ_AUFP01000023 (original name was: NZ_AUFP01000023.1)
  NZ_AUFP01000024 (original name was: NZ_AUFP01000024.1)
  NZ_AUFP01000025 (original name was: NZ_AUFP01000025.1)
  NZ_AUFP01000026 (original name was: NZ_AUFP01000026.1)
  NZ_AUFP01000027 (original name was: NZ_AUFP01000027.1)
  NZ_KE384543.1
  NZ_AUFP01000030 (original name was: NZ_AUFP01000030.1)
  NZ_AUFP01000031 (original name was: NZ_AUFP01000031.1)
  NZ_AUFP01000032 (original name was: NZ_AUFP01000032.1)
  NZ_AUFP01000033 (original name was: NZ_AUFP01000033.1)
  NZ_AUFP01000034 (original name was: NZ_AUFP01000034.1)
  NZ_AUFP01000035 (original name was: NZ_AUFP01000035.1)
  NZ_AUFP01000036 (original name was: NZ_AUFP01000036.1)
  NZ_AUFP01000037 (original name was: NZ_AUFP01000037.1)
  NZ_AUFP01000038 (original name was: NZ_AUFP01000038.1)
  NZ_AUFP01000039 (original name was: NZ_AUFP01000039.1)
  NZ_AUFP01000040 (original name was: NZ_AUFP01000040.1)
  NZ_AUFP01000041 (original name was: NZ_AUFP01000041.1)
  NZ_AUFP01000042 (original name was: NZ_AUFP01000042.1)
  NZ_AUFP01000043 (original name was: NZ_AUFP01000043.1)
  NZ_AUFP01000044 (original name was: NZ_AUFP01000044.1)
  NZ_AUFP01000045 (original name was: NZ_AUFP01000045.1)
  NZ_AUFP01000046 (original name was: NZ_AUFP01000046.1)
  NZ_AUFP01000047 (original name was: NZ_AUFP01000047.1)
  NZ_AUFP01000048 (original name was: NZ_AUFP01000048.1)

Compact view
c00001_NZ_AUFP.. - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 58,778 - 106,336 nt. (total: 47,559 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000194.1 |  | 0.22 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000888.1 |  | 0.21 | Other | bacilysin | Bacillus sp. CS93
BGC0001184.1 |  | 0.21 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000228.1 |  | 0.21 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000839.1 |  | 0.21 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0000886.1 |  | 0.21 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000237.1 |  | 0.21 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000272.1 |  | 0.21 | Polyketide | spore pigment | Streptomyces collinus
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000261.1 |  | 0.20 | Polyketide | R1128 | Streptomyces sp. R1128

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000194.1 |  | 0.55 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000888.1 |  | 0.54 | Other | bacilysin | Bacillus sp. CS93
BGC0001184.1 |  | 0.54 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000228.1 |  | 0.54 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000839.1 |  | 0.54 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0000886.1 |  | 0.53 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000237.1 |  | 0.53 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000272.1 |  | 0.53 | Polyketide | spore pigment | Streptomyces collinus
BGC0000248.1 |  | 0.53 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000261.1 |  | 0.53 | Polyketide | R1128 | Streptomyces sp. R1128

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_KE384540.1 - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 262,064 - 282,336 nt. (total: 20,273 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001779.1 |  | 0.17 | RiPP | siamycin | Streptomyces nodosus
BGC0001639.1 |  | 0.15 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000500.1 |  | 0.15 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000504.1 |  | 0.15 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000484.1 |  | 0.15 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000616.1 |  | 0.15 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000558.1 |  | 0.15 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001120.1 |  | 0.14 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001540.1 |  | 0.14 | Other | CC-1065 | Streptomyces zelensis
BGC0000243.1 |  | 0.14 | Polyketide | macrotetrolide | Streptomyces griseus subsp. griseus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001779.1 |  | 0.48 | RiPP | siamycin | Streptomyces nodosus
BGC0001639.1 |  | 0.46 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000500.1 |  | 0.46 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000504.1 |  | 0.46 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000484.1 |  | 0.45 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000616.1 |  | 0.45 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000558.1 |  | 0.45 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001120.1 |  | 0.43 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001540.1 |  | 0.43 | Other | CC-1065 | Streptomyces zelensis
BGC0000243.1 |  | 0.43 | Polyketide | macrotetrolide | Streptomyces griseus subsp. griseus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names