LOCUS       c00080_NZ_WSRS..        7242 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_WSRS01000026.1 Streptococcus danieliae strain NM51_B2-22
            NODE_26_length_19578_cov_73.2557, whole genome shotgun sequence.
ACCESSION   NZ_WSRS01000026
VERSION     NZ_WSRS01000026
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:43:44
            Original ID  :: NZ_WSRS01000026.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7242
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7242
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[244:2242](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      245..2242
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..7242
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7242
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             245..2242
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 312.9; E-value:
                     7.4e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_1"
                     /sec_met_domain="TIGR01193 (E-value: 7.8e-204, bitscore:
                     668.3, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.1e-23, bitscore:
                     70.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNGTTAYGLVKAGQELGLACQPLKLDLEQLQEALVQNPALVHVIK
                     EGKFPHYYVVYQVTDTAVFLADPDPQVGLVKRSHAEFLQEWTGVALVFEPRSDYQPNQR
                     REATFWSLLALLFQMKGLFFLIVLVSLGLTLLTILSSYGLQWIVDGYLPQGRMEAISQL
                     SLWLLVAALLQALLQFCKQYPLLLLSRRLSLKLLEDYLSHVFGLPLSFFATRRSGEILS
                     RFTDANQIIEALASLGLTLLLDGLTLVSLSLALAWQSPQLFLLALVLVPLYTLLFFAFQ
                     KKFKSYHQDQLEAGSQLSSSLMDHIKGMETLKALGLEDGALAQNKGYLESFWDKVCTYS
                     CAEQLQLALKSALQLGTTVAIFWWGSRLILTGHLSLGQLLTFTSLLAYFTGPLENLLQI
                     QVQVQKAQVAYQRLQEVYQVPLEGQQGLETLTGTQGVLRLDQVSFAYDYGSPLLKDLTL
                     DIPPGQKLGILGLSGCGKTSLAKLLVGFYQPLEGRVLLAGQDLSCLHPQELRRQVQYVA
                     QDAGLFQGTLRENLLWPAAAETAEADLWAALELVEAVAFVQLLPLGLDTLVGTDGTALS
                     TGQIQRLVLARSLLTGASCLILDEATSHLDPETEERVFDRLLALDQTLIVITHRLELAQ
                     KLERIVVLADGCLKETGEKEAIYLGQESGF"
     PFAM_domain     248..535
                     /aSDomain="Peptidase_C39"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03412.17"
                     /description="Peptidase C39 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_1_0001"
                     /evalue="9.70E-20"
                     /label="ctg80_1"
                     /locus_tag="ctg80_1"
                     /protein_end="97"
                     /protein_start="1"
                     /score="70.8"
                     /tool="antismash"
                     /translation="NGTTAYGLVKAGQELGLACQPLKLDLEQLQEALVQNPALVHVIKE
                     GKFPHYYVVYQVTDTAVFLADPDPQVGLVKRSHAEFLQEWTGVALVFEPRS"
     aSDomain        248..2215
                     /aSDomain="TIGR01193"
                     /aSTool="tigrfam"
                     /description="bacteriocin_ABC: ABC-type bacteriocin
                     transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg80_1_0001"
                     /evalue="3.50E-201"
                     /identifier="TIGR01193"
                     /label="ctg80_1"
                     /locus_tag="ctg80_1"
                     /protein_end="657"
                     /protein_start="1"
                     /score="668.3"
                     /tool="antismash"
                     /translation="NGTTAYGLVKAGQELGLACQPLKLDLEQLQEALVQNPALVHVIKE
                     GKFPHYYVVYQVTDTAVFLADPDPQVGLVKRSHAEFLQEWTGVALVFEPRSDYQPNQRR
                     EATFWSLLALLFQMKGLFFLIVLVSLGLTLLTILSSYGLQWIVDGYLPQGRMEAISQLS
                     LWLLVAALLQALLQFCKQYPLLLLSRRLSLKLLEDYLSHVFGLPLSFFATRRSGEILSR
                     FTDANQIIEALASLGLTLLLDGLTLVSLSLALAWQSPQLFLLALVLVPLYTLLFFAFQK
                     KFKSYHQDQLEAGSQLSSSLMDHIKGMETLKALGLEDGALAQNKGYLESFWDKVCTYSC
                     AEQLQLALKSALQLGTTVAIFWWGSRLILTGHLSLGQLLTFTSLLAYFTGPLENLLQIQ
                     VQVQKAQVAYQRLQEVYQVPLEGQQGLETLTGTQGVLRLDQVSFAYDYGSPLLKDLTLD
                     IPPGQKLGILGLSGCGKTSLAKLLVGFYQPLEGRVLLAGQDLSCLHPQELRRQVQYVAQ
                     DAGLFQGTLRENLLWPAAAETAEADLWAALELVEAVAFVQLLPLGLDTLVGTDGTALST
                     GQIQRLVLARSLLTGASCLILDEATSHLDPETEERVFDRLLALDQTLIVITHRLELAQK
                     LERIVVLADGCLKETGEKEAI"
     PFAM_domain     614..1423
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_1_0002"
                     /evalue="1.60E-44"
                     /label="ctg80_1"
                     /locus_tag="ctg80_1"
                     /protein_end="393"
                     /protein_start="123"
                     /score="152.7"
                     /tool="antismash"
                     /translation="FLIVLVSLGLTLLTILSSYGLQWIVDGYLPQGRMEAISQLSLWLL
                     VAALLQALLQFCKQYPLLLLSRRLSLKLLEDYLSHVFGLPLSFFATRRSGEILSRFTDA
                     NQIIEALASLGLTLLLDGLTLVSLSLALAWQSPQLFLLALVLVPLYTLLFFAFQKKFKS
                     YHQDQLEAGSQLSSSLMDHIKGMETLKALGLEDGALAQNKGYLESFWDKVCTYSCAEQL
                     QLALKSALQLGTTVAIFWWGSRLILTGHLSLGQLLTFTSLLAYFTGPL"
     PFAM_domain     1601..2053
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_1_0003"
                     /evalue="6.90E-29"
                     /label="ctg80_1"
                     /locus_tag="ctg80_1"
                     /protein_end="603"
                     /protein_start="452"
                     /score="101.2"
                     /tool="antismash"
                     /translation="LKDLTLDIPPGQKLGILGLSGCGKTSLAKLLVGFYQPLEGRVLLA
                     GQDLSCLHPQELRRQVQYVAQDAGLFQGTLRENLLWPAAAETAEADLWAALELVEAVAF
                     VQLLPLGLDTLVGTDGTALSTGQIQRLVLARSLLTGASCLILDEATS"
     CDS             complement(2503..3306)
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="MIRFLILAGYFELSLYLTWSGKLDHYINLHYSYLAYLSMALTFLL
                     ALIQLRLLILEEKEKGKTSQPVAYLVLALPLLIGFLFPTVSLDSTTVSAKGYQFPLAAG
                     ASAEIQADEGTSSQYLKPDTSSYFTKKAYDTEMQAVAAKYLKEDTIQVTTQNYMEFMEA
                     LYDYPDQFLGKEVQMTGFVYNDPKQSQQQFLFRFGIIHCIADSGVYGLLTTGQDQSYPD
                     NTWVTAKGKIAIHFHKDLNQSLPTLELTNWERVEEPANPYVYREF"
     aSDomain        complement(2521..3252)
                     /aSDomain="TIGR03943"
                     /aSTool="tigrfam"
                     /description="TIGR03943: TIGR03943 family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg80_2_0002"
                     /evalue="3.80E-51"
                     /identifier="TIGR03943"
                     /label="ctg80_2"
                     /locus_tag="ctg80_2"
                     /protein_end="262"
                     /protein_start="18"
                     /score="171.5"
                     /tool="antismash"
                     /translation="WSGKLDHYINLHYSYLAYLSMALTFLLALIQLRLLILEEKEKGKT
                     SQPVAYLVLALPLLIGFLFPTVSLDSTTVSAKGYQFPLAAGASAEIQADEGTSSQYLKP
                     DTSSYFTKKAYDTEMQAVAAKYLKEDTIQVTTQNYMEFMEALYDYPDQFLGKEVQMTGF
                     VYNDPKQSQQQFLFRFGIIHCIADSGVYGLLTTGQDQSYPDNTWVTAKGKIAIHFHKDL
                     NQSLPTLELTNWERVEEPANPY"
     PFAM_domain     complement(2785..3306)
                     /aSDomain="DUF1980"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09323.12"
                     /description="Domain of unknown function (DUF1980)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_2_0004"
                     /evalue="3.90E-54"
                     /label="ctg80_2"
                     /locus_tag="ctg80_2"
                     /protein_end="174"
                     /protein_start="0"
                     /score="183.4"
                     /tool="antismash"
                     /translation="MIRFLILAGYFELSLYLTWSGKLDHYINLHYSYLAYLSMALTFLL
                     ALIQLRLLILEEKEKGKTSQPVAYLVLALPLLIGFLFPTVSLDSTTVSAKGYQFPLAAG
                     ASAEIQADEGTSSQYLKPDTSSYFTKKAYDTEMQAVAAKYLKEDTIQVTTQNYMEFMEA
                     LYDYPDQFLGK"
     CDS             complement(3303..4202)
                     /locus_tag="ctg80_3"
                     /transl_table=11
                     /translation="MFSELPASFLQMSAIFLSIVIEALPFVLLGSIISGFIEVYLTPEK
                     VVAALPKNRFLNILIGSFAGLIFPSCECGIVPIIHRFLKKKVPTYTAIPFLVTAPVINP
                     IVLFATFSAFGNSWLFALTRALGSFILAQALGLLLGFVWTEDILVSHKNLPLHGHKHTD
                     PKQGRLFQSWVHAIDEFFDSGCYLILGALFASCVQVYVPTRILTSISSNPLVAILILML
                     LSFLLSLCSEADAFIGSSLLGTFGMAPVMAFLVIGPVLDIKNLLMMTRVFKKSFIRNFI
                     LITAVLVFLFAASLEVFL"
     PFAM_domain     complement(3327..4175)
                     /aSDomain="ArsP_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03773.15"
                     /description="Predicted permease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_3_0005"
                     /evalue="1.40E-62"
                     /label="ctg80_3"
                     /locus_tag="ctg80_3"
                     /protein_end="292"
                     /protein_start="9"
                     /score="211.6"
                     /tool="antismash"
                     /translation="LQMSAIFLSIVIEALPFVLLGSIISGFIEVYLTPEKVVAALPKNR
                     FLNILIGSFAGLIFPSCECGIVPIIHRFLKKKVPTYTAIPFLVTAPVINPIVLFATFSA
                     FGNSWLFALTRALGSFILAQALGLLLGFVWTEDILVSHKNLPLHGHKHTDPKQGRLFQS
                     WVHAIDEFFDSGCYLILGALFASCVQVYVPTRILTSISSNPLVAILILMLLSFLLSLCS
                     EADAFIGSSLLGTFGMAPVMAFLVIGPVLDIKNLLMMTRVFKKSFIRNFILITAVLVFL
                     FA"
     CDS             4417..4860
                     /locus_tag="ctg80_4"
                     /transl_table=11
                     /translation="MRLRGFELVTAYTDSQLLPKRETAHAAGYDLKVAEAMVIGPGEIR
                     LVPTGVKAYMQANEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNEANEGHIFAQMQN
                     ITDQPVALEVGERIVQAVFAPFLLADDDQAGGQRQGGFGSTGR"
     PFAM_domain     4468..4854
                     /aSDomain="dUTPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00692.21"
                     /description="dUTPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_4_0006"
                     /evalue="4.00E-15"
                     /label="ctg80_4"
                     /locus_tag="ctg80_4"
                     /protein_end="146"
                     /protein_start="17"
                     /score="55.7"
                     /tool="antismash"
                     /translation="LPKRETAHAAGYDLKVAEAMVIGPGEIRLVPTGVKAYMQANEVLY
                     LYDRSSNPRKKGLVLINSVGVIDGDYYGNEANEGHIFAQMQNITDQPVALEVGERIVQA
                     VFAPFLLADDDQAGGQRQGGFGSTG"
     aSDomain        4869..6212
                     /aSDomain="TIGR00416"
                     /aSTool="tigrfam"
                     /description="sms: DNA repair protein RadA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg80_5_0003"
                     /evalue="1.50E-191"
                     /identifier="TIGR00416"
                     /label="ctg80_5"
                     /locus_tag="ctg80_5"
                     /protein_end="448"
                     /protein_start="0"
                     /score="635.0"
                     /tool="antismash"
                     /translation="MAKKKSTFICQNCDYHSPKYMGRCPNCGAWSSFVEEIEQAEVKHA
                     RVSLTGEKAKPMKLNQVTSVDVSRTRTGLEEFNRVLGGGVVPGSLVLIGGDPGIGKSTL
                     LLQVSTQLSRLGTVLYVSGEESAEQIKLRAERLGDPDSDFYLYAETNMDSIRTEVERLK
                     PDFLIIDSIQTILSPEISSVQGSVSQVREVTNQLMQLAKTNKIATFIVGHMTKEGTLAG
                     PRTLEHMVDTVLYFEGERQHTFRILRAVKNRFGSTNEIGIFEMQAEGLVEVQNPSQVFL
                     EERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLIMAVLEK
                     RAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDLPTRPDEAFIGEIGLTGEI
                     RRVNRVEQRIQEAAKLGFKRIYVPQNSLQGVTLPQGIEIIGVTRIGEVL"
     CDS             4869..6230
                     /locus_tag="ctg80_5"
                     /transl_table=11
                     /translation="MAKKKSTFICQNCDYHSPKYMGRCPNCGAWSSFVEEIEQAEVKHA
                     RVSLTGEKAKPMKLNQVTSVDVSRTRTGLEEFNRVLGGGVVPGSLVLIGGDPGIGKSTL
                     LLQVSTQLSRLGTVLYVSGEESAEQIKLRAERLGDPDSDFYLYAETNMDSIRTEVERLK
                     PDFLIIDSIQTILSPEISSVQGSVSQVREVTNQLMQLAKTNKIATFIVGHMTKEGTLAG
                     PRTLEHMVDTVLYFEGERQHTFRILRAVKNRFGSTNEIGIFEMQAEGLVEVQNPSQVFL
                     EERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLIMAVLEK
                     RAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDLPTRPDEAFIGEIGLTGEI
                     RRVNRVEQRIQEAAKLGFKRIYVPQNSLQGVTLPQGIEIIGVTRIGEVLQKVFG"
     PFAM_domain     4890..4973
                     /aSDomain="Rubredoxin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18073.3"
                     /description="Rubredoxin metal binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_5_0007"
                     /evalue="1.70E-10"
                     /label="ctg80_5"
                     /locus_tag="ctg80_5"
                     /protein_end="35"
                     /protein_start="7"
                     /score="40.4"
                     /tool="antismash"
                     /translation="FICQNCDYHSPKYMGRCPNCGAWSSFVE"
     PFAM_domain     5058..5522
                     /aSDomain="AAA_25"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13481.8"
                     /description="AAA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_5_0008"
                     /evalue="4.90E-14"
                     /label="ctg80_5"
                     /locus_tag="ctg80_5"
                     /protein_end="218"
                     /protein_start="63"
                     /score="52.4"
                     /tool="antismash"
                     /translation="SVDVSRTRTGLEEFNRVLGGGVVPGSLVLIGGDPGIGKSTLLLQV
                     STQLSRLGTVLYVSGEESAEQIKLRAERLGDPDSDFYLYAETNMDSIRTEVERLKPDFL
                     IIDSIQTILSPEISSVQGSVSQVREVTNQLMQLAKTNKIATFIVGHMTKEG"
     PFAM_domain     5946..6143
                     /aSDomain="ChlI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13541.8"
                     /description="Subunit ChlI of Mg-chelatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_5_0009"
                     /evalue="1.10E-09"
                     /label="ctg80_5"
                     /locus_tag="ctg80_5"
                     /protein_end="425"
                     /protein_start="359"
                     /score="38.3"
                     /tool="antismash"
                     /translation="KLDEPAIDLAVAVAIASSYKDLPTRPDEAFIGEIGLTGEIRRVNR
                     VEQRIQEAAKLGFKRIYVPQN"
     CDS             6227..6883
                     /locus_tag="ctg80_6"
                     /transl_table=11
                     /translation="MKYDVILLVAGSGRRMGAACNKVFLELEGQAIFTYSLEVFQADPD
                     CGRIVLVGRPEEQAAFADYLSQQVVFVAGGAERQDSVRLGLAQVEADWVMVHDGARPFI
                     SLEQLQGLKAQPNSILAVPVTDTIKEVGSEFIQRTVPRESLMAAQTPQFFERRLLAEVH
                     EQALQAGYLGTDDASLVEAFSEVQVGLVPGSSWNLKLTRPEDLVLGQAIRKEVFQ"
     aSDomain        6239..6859
                     /aSDomain="TIGR00453"
                     /aSTool="tigrfam"
                     /description="ispD: 2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg80_6_0004"
                     /evalue="1.50E-63"
                     /identifier="TIGR00453"
                     /label="ctg80_6"
                     /locus_tag="ctg80_6"
                     /protein_end="211"
                     /protein_start="4"
                     /score="212.2"
                     /tool="antismash"
                     /translation="VILLVAGSGRRMGAACNKVFLELEGQAIFTYSLEVFQADPDCGRI
                     VLVGRPEEQAAFADYLSQQVVFVAGGAERQDSVRLGLAQVEADWVMVHDGARPFISLEQ
                     LQGLKAQPNSILAVPVTDTIKEVGSEFIQRTVPRESLMAAQTPQFFERRLLAEVHEQAL
                     QAGYLGTDDASLVEAFSEVQVGLVPGSSWNLKLTRPEDLVLGQA"
     PFAM_domain     6239..6862
                     /aSDomain="IspD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01128.21"
                     /description="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg80_6_0010"
                     /evalue="7.20E-60"
                     /label="ctg80_6"
                     /locus_tag="ctg80_6"
                     /protein_end="212"
                     /protein_start="4"
                     /score="202.6"
                     /tool="antismash"
                     /translation="VILLVAGSGRRMGAACNKVFLELEGQAIFTYSLEVFQADPDCGRI
                     VLVGRPEEQAAFADYLSQQVVFVAGGAERQDSVRLGLAQVEADWVMVHDGARPFISLEQ
                     LQGLKAQPNSILAVPVTDTIKEVGSEFIQRTVPRESLMAAQTPQFFERRLLAEVHEQAL
                     QAGYLGTDDASLVEAFSEVQVGLVPGSSWNLKLTRPEDLVLGQAI"
ORIGIN
        1 tacaatattt gtcgttttga acagatcaaa cgactgaatt tgaatacatg ggcttagtgc
       61 gcccaaaaat cagaattctc ccgataatcg ggatagaaaa gtaggaaata cagggacttt
      121 tgctggaaat tggagggcaa gagtcccttc tttttttata tgacggaata cttctggttt
      181 ttagaggtgc ccttatgggt cagactactc cctggcctat ttacggacgc taagcaagac
      241 caacttgaac ggaacaacag cctatggcct agtcaaggct ggtcaagagt tggggttggc
      301 ctgccaaccc ctgaagttgg atctggagca gttgcaggag gccctggtcc agaatccggc
      361 cctggtccat gtcattaagg agggaaagtt tccgcattat tatgtcgttt atcaggtcac
      421 agacacggcg gtttttctag cggatccaga tccgcaagtt ggcttggtca aacgatctca
      481 tgcggagttt cttcaggagt ggacgggtgt tgccctcgtt tttgaaccga ggtctgacta
      541 tcaacccaac caacggcggg aggcgacatt ttggtccctc ttggccttgc tttttcagat
      601 gaaggggtta tttttcctga tagtcctagt aagtcttggt ctaaccctgc tgaccatcct
      661 gtcctcctat ggtttgcagt ggattgtgga tggttacctg ccccaggggc ggatggaggc
      721 gattagtcag ttgagcttgt ggctattagt ggcagccctg ttgcaggctc tccttcaatt
      781 ctgcaagcag tatcccttgt tgcttctgag tcgccggctt tccttaaagc tgttggagga
      841 ctatctgagc catgttttcg gcttgccact cagttttttc gcaacccgcc gcagcggtga
      901 aatcctttcc cgctttacag atgccaatca gattattgag gccttggcct cactgggcct
      961 gaccctgctg ctggatggtc taactctggt cagcctcagt ttggccctgg cctggcaatc
     1021 gccccagctc tttttgctgg ctctagtttt ggtgccgctg tataccctct tgttttttgc
     1081 ctttcagaaa aaatttaaga gctatcacca ggatcagttg gaggcgggct cccaactatc
     1141 ctctagtttg atggaccaca tcaaggggat ggaaaccttg aaggcattgg ggcttgagga
     1201 cggagccctg gctcagaata agggctattt agaaagcttt tgggacaagg tctgcaccta
     1261 cagttgtgca gagcagctac agttagcgct gaaaagcgcc ctgcagctcg ggacaaccgt
     1321 tgccatcttt tggtggggat cgcggctcat cctgaccgga catctgagcc tgggtcagct
     1381 cttgaccttt accagtcttt tggcctattt tacaggtccc ttggagaatc tgctccagat
     1441 tcaggtacag gtccagaagg cccaggtggc ctaccaaagg ctacaggaag tttaccaagt
     1501 ccctttggag ggccagcagg gactcgagac gcttaccggg actcagggag ttttgcggct
     1561 agaccaggtc agttttgcct atgattacgg cagtcccttg ctcaaggatc tgacgctgga
     1621 tattcctccg gggcagaagc tgggaatcct ggggctttcg ggttgcggaa aaaccagtct
     1681 ggctaaattg ttagttggct tttaccagcc tttggaaggc cgagtcctgt tggcaggtca
     1741 agacctgtcc tgcctccatc cgcaggagct gcgacgacag gtccagtatg tggctcagga
     1801 tgccggactt tttcaaggaa ccctgcggga gaatcttctc tggcctgcag cagctgagac
     1861 agcagaagcg gatttatggg cagctttgga gttggtggag gcggttgcct ttgtccagct
     1921 cctgcccctg ggcttagaca ctctggtggg aacggatggg actgccctgt cgacagggca
     1981 gatccaacgg ctggtcctgg ctcgtagcct cttgaccggg gcctcctgct tgattcttga
     2041 tgaagcgacc agtcacctag atcccgaaac agaggaacgc gtctttgacc gcctgctggc
     2101 tctggaccaa accctgattg tcatcactca tcgcctggag ctggctcaga agctagagcg
     2161 gatcgtggtg ctcgcagatg gctgcttaaa agagactggg gagaaggagg caatttatct
     2221 gggacaagaa tctggttttt agttgctaga tccagaactt tttgcttaga atgatagtag
     2281 agctaagacc cctcttggct atctcgtggt tgagagggtg agtttttcga attgggtttg
     2341 tggtggacac cgcggacgag agcttaaaac cacagtggga gtgggacaga actaaatttg
     2401 aaaaaattta gttctgtccc actccctttt tatagaatcg aaccaagtaa aaagccccac
     2461 tgtcagggtc agcgtgaagc ggacagtgag gttagacttc tgctaaaatt cgcgatagac
     2521 ataggggtta gcaggttctt caacgcgttc ccagttggtg agttctaagg ttggtaggct
     2581 ttggttgagg tccttgtgga agtggatggc gattttgccc ttggctgtga cccaggtgtt
     2641 gtcggggtag gactggtctt ggccggtggt taagaggccg taaacgccag agtctgcgat
     2701 gcagtggatg atgccgaagc gaaagaggaa ttgttgttgg ctttgtttgg ggtcgttgta
     2761 gacgaagccg gtcatttgga cttccttgcc caggaactgg tcggggtaat cgtagagggc
     2821 ttccataaat tccatgtagt tttgggtcgt tacctggatg gtgtcttctt tcaggtattt
     2881 ggctgcgact gcctgcattt cggtatcata ggcttttttg gtgaaatagg agctggtgtc
     2941 gggtttgagg tactggctgc tggttccttc atcggcctgg atttctgcgg atgccccagc
     3001 cgcgaggggg aattggtagc ccttagccga gacagtcgtg gaatctaggc tgacggtggg
     3061 aaagagaaag ccgattagga gtgggagtgc caggacaagg taggctactg gctgactggt
     3121 tttgcccttt tctttttctt ccaagatcaa caagcgcaat tgaatgaggg cgagtaggaa
     3181 ggttagggcc atagagaggt aggccaggta ggagtagtgg aggttgatgt agtggtcgag
     3241 tttgccgctc caggtcaggt agaggctgag ttcaaagtag ccggctagga ttaaaaagcg
     3301 aatcatagga aaacctccaa actagcagcg aaaaggaaaa caaggacggc ggtgatgagg
     3361 ataaaattgc ggataaagga ttttttgaaa acacgggtca tcatgagcag gttcttaatg
     3421 tccaggacgg gtccgatgac taaaaaggcc atcacgggag ccatgccgaa ggtgcccaag
     3481 agagaggagc cgataaaggc gtctgcctca ctacaaagag aaagcagaaa gctcaggagc
     3541 atcaagatga gaatcgctac caaggggttg ctggaaatgc tggtgaggat gcgggttggg
     3601 acatagactt gcacacagct ggcgaagagg gcgcctaaaa tgaggtagca gccagaatcg
     3661 aaaaattcat caatggcgtg gacccaggat tggaaaaggc gaccttgttt aggatcggtg
     3721 tgcttgtggc cgtgtagggg gaggttctta tggctgacca agatatcctc ggtccagaca
     3781 aagcctagaa gcaggccgag ggcttgggcc aggatgaagg aaccgagggc ccgtgtcagg
     3841 gcgaagagcc aggaattgcc aaaggccgaa aaggtcgcaa acaaaacgat gggattaatg
     3901 accggggcgg tcactagaaa agggatggcg gtataggttg ggaccttctt tttgaggaag
     3961 cgatgaatga tggggacaat cccacattca caggaaggga aaatcaagcc cgcaaaggag
     4021 ccgattagaa tattcaaaaa acgattttta gggagggccg caacaacttt ttctggagtg
     4081 aggtagactt caataaagcc cgagataatg ctgcctagga gcacaaaggg gagggcttca
     4141 ataacaatgg atagaaaaat cgcggacatt tgtagaaaac tcgcaggtag ttcagaaaac
     4201 ataggagctc ctttctgttt gtttaccatt atatcaaaag caggggactt cagagatcga
     4261 ccgatttttg acagagtcag aggcagggct ttggtgtata atagggaaat ggcactcttg
     4321 ctattttgct tcaaaggctg ttagcttcga cgtgctgcct tgtttgaatg taaattagtc
     4381 tgagtcataa ttgcagaatg aaaaaaggag gaaatcatgc gtctacgtgg atttgaattg
     4441 gtgacagcct atactgattc ccagcttttg cccaaacggg aaacagctca tgcagcgggc
     4501 tatgatttaa aggttgcaga agctatggtg attgggccag gtgaaattcg tttggtcccg
     4561 actggagtca aggcttacat gcaggccaac gaagttttat acctctatga ccgttcttcc
     4621 aacccgcgca agaagggctt ggtattgatc aactccgtcg gcgtgattga tggggattat
     4681 tacggcaatg aagccaatga aggacacatt tttgcgcaaa tgcagaacat cacggatcaa
     4741 ccggttgcct tagaagttgg tgagcggatt gtacaggcgg tttttgcgcc tttcctcttg
     4801 gcggatgatg atcaagccgg tggtcaacgt caaggtggtt ttggctcaac gggtcgctag
     4861 gaggagcgat ggctaagaag aaatcaacct ttatttgcca aaactgtgac taccattctc
     4921 ctaaatatat gggccgttgt cccaactgtg gtgcctggtc ttcttttgtg gaagaaattg
     4981 aacaagctga ggtcaaacat gcgcgtgtga gtctgaccgg tgaaaaggcg aagcccatga
     5041 aactcaatca ggtaacgtct gtcgatgtct cgcggactcg gactggccta gaagaattca
     5101 accgtgtcct cggtggtggt gtggttcctg gtagtctggt cttgattgga ggagatccag
     5161 ggattggcaa gtcgaccttg ctcttgcagg tgtcgacaca attgtcccga ttgggaaccg
     5221 ttctctatgt gagtggggag gagtcggcag aacaaatcaa gttacgggcg gagcgtctag
     5281 gggatccgga ttcggatttc tacctgtatg cggaaaccaa catggatagc attcggacgg
     5341 aagtcgaacg cttaaagcca gacttcctta ttattgactc catccaaacg attttgtctc
     5401 cggagatttc cagtgtgcag gggtccgtga gccaggtgcg ggaagtaacc aaccagctca
     5461 tgcagctggc caagaccaat aaaattgcga cttttattgt gggtcacatg accaaggagg
     5521 gaaccctggc gggacctcgg accttggagc atatggtgga tacggttctc tattttgagg
     5581 gggagcgcca gcacaccttt cggattttgc gggctgtcaa aaatcgcttt ggttcgacca
     5641 atgaaattgg tatttttgag atgcaggctg aaggtttggt ggaggtgcag aatccgagtc
     5701 aggtcttctt ggaagaacgt ttggatgggg cgacgggttc ctcgattgtg gtgaccatgg
     5761 aagggactag gccgattttg gccgaggttc aggccttggt aaccccgacc atgtttggta
     5821 atgccaagcg gacaacaacg ggcttggatt ttaaccgggc cagcctgatt atggcggttt
     5881 tagagaagcg ggcgggactg ctcttgcaga accaggatgc ctatcttaag tctgctggtg
     5941 gggttaaatt ggatgagccg gcaattgatt tggctgttgc agttgcgatt gcttcttcct
     6001 ataaagattt gccgacccgg cctgatgaag cctttattgg cgagattggt ctgacaggtg
     6061 agattcgccg ggtaaaccgt gtggagcaac ggatccagga agcggccaag ttaggtttta
     6121 agcggatcta tgtcccgcaa aattctctcc aaggggtaac attgcctcaa ggaattgaga
     6181 ttatcggagt tactcggatt ggggaagtcc tacagaaggt gtttggatga agtatgatgt
     6241 gattttatta gtcgcaggtt ctggccgccg gatgggggct gcttgcaaca aagttttttt
     6301 ggagttggaa ggccaggcta tttttaccta tagccttgag gttttccaag cagatcctga
     6361 ctgtggacga attgttctgg tcggccggcc cgaagagcag gctgcttttg cagattattt
     6421 gtcgcagcag gttgtttttg tagctggtgg ggcggaacgt caggactcgg tgcggctagg
     6481 tctggctcag gttgaggctg actgggttat ggttcatgat ggagcccgtc ccttcattag
     6541 tctggagcaa ctgcagggac ttaaggcgca gcccaattct atcttagctg tgccggtgac
     6601 agatactatc aaggaggtgg ggtctgagtt tatccagcgg acagttccgc gggagagctt
     6661 aatggcggct cagacgcctc agttttttga gcgtcgttta ctggctgagg tccatgagca
     6721 ggccttgcag gcgggttatt tggggaccga tgatgccagt ctggtggagg cctttagtga
     6781 ggttcaggtg ggtctggttc caggttcttc ttggaatctg aagctgacaa ggccggaaga
     6841 cctggtttta ggtcaggcaa ttaggaagga agtgtttcaa tgatccgaat tggccagggt
     6901 tacgatgttc atgagttggt tccaggccgt cccttgattg tgggtggtgt gaacttgccc
     6961 tttgaccgtg ggctcaaggg gcattcggat gcggatgtac tccttcatgc gatcaccgat
     7021 gcgctgatcg gagcactcgg acgtggggat atcggtcatg cctttcctga cagcaatccc
     7081 gaattggcag gccttgcttc tacaaaaatt ttagcagcta tttatgaaga aatgagaaaa
     7141 gcggattacc gtgtgggcaa tttggatgcg accattttgg ccgagcggcc caaaatggcg
     7201 ccgcatctgc ctgagatgaa aaaaaggatt gcaggcctac tc
//
