GCF_001682915.1_ASM168291v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_LSME01000001 (original name was: NZ_LSME01000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	4,048	47,911	turnerbactin	NRP	30%
Region 1.2	thiopeptide	351,546	377,854	O-antigen	Saccharide	14%

NZ_LSME01000014 (original name was: NZ_LSME01000014.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	RiPP-like	107,837	116,083

NZ_LSME01000003 (original name was: NZ_LSME01000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	butyrolactone	70,382	82,025

NZ_LSME01000004 (original name was: NZ_LSME01000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	arylpolyene	9,360	52,956	aryl polyenes	Other	88%

No secondary metabolite regions were found in these records:: NZ_LSME01000010 (original name was: NZ_LSME01000010.1); NZ_LSME01000011 (original name was: NZ_LSME01000011.1); NZ_LSME01000012 (original name was: NZ_LSME01000012.1); NZ_LSME01000013 (original name was: NZ_LSME01000013.1); NZ_LSME01000015 (original name was: NZ_LSME01000015.1); NZ_LSME01000016 (original name was: NZ_LSME01000016.1); NZ_LSME01000017 (original name was: NZ_LSME01000017.1); NZ_LSME01000018 (original name was: NZ_LSME01000018.1); NZ_LSME01000019 (original name was: NZ_LSME01000019.1); NZ_LSME01000002 (original name was: NZ_LSME01000002.1); NZ_LSME01000020 (original name was: NZ_LSME01000020.1); NZ_LSME01000021 (original name was: NZ_LSME01000021.1); NZ_LSME01000022 (original name was: NZ_LSME01000022.1); NZ_LSME01000023 (original name was: NZ_LSME01000023.1); NZ_LSME01000024 (original name was: NZ_LSME01000024.1); NZ_LSME01000025 (original name was: NZ_LSME01000025.1); NZ_LSME01000026 (original name was: NZ_LSME01000026.1); NZ_LSME01000027 (original name was: NZ_LSME01000027.1); NZ_LSME01000028 (original name was: NZ_LSME01000028.1); NZ_LSME01000029 (original name was: NZ_LSME01000029.1); NZ_LSME01000030 (original name was: NZ_LSME01000030.1); NZ_LSME01000031 (original name was: NZ_LSME01000031.1); NZ_LSME01000032 (original name was: NZ_LSME01000032.1); NZ_LSME01000033 (original name was: NZ_LSME01000033.1); NZ_LSME01000034 (original name was: NZ_LSME01000034.1); NZ_LSME01000035 (original name was: NZ_LSME01000035.1); NZ_LSME01000036 (original name was: NZ_LSME01000036.1); NZ_LSME01000037 (original name was: NZ_LSME01000037.1); NZ_LSME01000038 (original name was: NZ_LSME01000038.1); NZ_LSME01000039 (original name was: NZ_LSME01000039.1); NZ_LSME01000040 (original name was: NZ_LSME01000040.1); NZ_LSME01000041 (original name was: NZ_LSME01000041.1); NZ_LSME01000042 (original name was: NZ_LSME01000042.1); NZ_LSME01000043 (original name was: NZ_LSME01000043.1); NZ_LSME01000044 (original name was: NZ_LSME01000044.1); NZ_LSME01000045 (original name was: NZ_LSME01000045.1); NZ_LSME01000046 (original name was: NZ_LSME01000046.1); NZ_LSME01000047 (original name was: NZ_LSME01000047.1); NZ_LSME01000048 (original name was: NZ_LSME01000048.1); NZ_LSME01000049 (original name was: NZ_LSME01000049.1); NZ_LSME01000005 (original name was: NZ_LSME01000005.1); NZ_LSME01000050 (original name was: NZ_LSME01000050.1); NZ_LSME01000051 (original name was: NZ_LSME01000051.1); NZ_LSME01000052 (original name was: NZ_LSME01000052.1); NZ_LSME01000053 (original name was: NZ_LSME01000053.1); NZ_LSME01000054 (original name was: NZ_LSME01000054.1); NZ_LSME01000055 (original name was: NZ_LSME01000055.1); NZ_LSME01000056 (original name was: NZ_LSME01000056.1); NZ_LSME01000057 (original name was: NZ_LSME01000057.1); NZ_LSME01000058 (original name was: NZ_LSME01000058.1); NZ_LSME01000059 (original name was: NZ_LSME01000059.1); NZ_LSME01000006 (original name was: NZ_LSME01000006.1); NZ_LSME01000060 (original name was: NZ_LSME01000060.1); NZ_LSME01000061 (original name was: NZ_LSME01000061.1); NZ_LSME01000062 (original name was: NZ_LSME01000062.1); NZ_LSME01000063 (original name was: NZ_LSME01000063.1); NZ_LSME01000064 (original name was: NZ_LSME01000064.1); NZ_LSME01000065 (original name was: NZ_LSME01000065.1); NZ_LSME01000066 (original name was: NZ_LSME01000066.1); NZ_LSME01000067 (original name was: NZ_LSME01000067.1); NZ_LSME01000068 (original name was: NZ_LSME01000068.1); NZ_LSME01000069 (original name was: NZ_LSME01000069.1); NZ_LSME01000007 (original name was: NZ_LSME01000007.1); NZ_LSME01000070 (original name was: NZ_LSME01000070.1); NZ_LSME01000071 (original name was: NZ_LSME01000071.1); NZ_LSME01000072 (original name was: NZ_LSME01000072.1); NZ_LSME01000073 (original name was: NZ_LSME01000073.1); NZ_LSME01000074 (original name was: NZ_LSME01000074.1); NZ_LSME01000075 (original name was: NZ_LSME01000075.1); NZ_LSME01000076 (original name was: NZ_LSME01000076.1); NZ_LSME01000077 (original name was: NZ_LSME01000077.1); NZ_LSME01000078 (original name was: NZ_LSME01000078.1); NZ_LSME01000079 (original name was: NZ_LSME01000079.1); NZ_LSME01000008 (original name was: NZ_LSME01000008.1); NZ_LSME01000009 (original name was: NZ_LSME01000009.1)

Compact view

c00001_NZ_LSME.. - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 4,048 - 47,911 nt. (total: 43,864 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.34	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.33	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.29	NRP	paenibactin	Paenibacillus elgii B69
BGC0001833.1	0.25	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131.1	0.24	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.24	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001591.1	0.23	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.23	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001758.1	0.23	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.67	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.62	NRP	paenibactin	Paenibacillus elgii B69
BGC0001833.1	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001131.1	0.57	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.57	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001132.1	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001591.1	0.57	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.57	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001758.1	0.56	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 4047 - 47911:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_20

Search NORINE for peptide: strict or relaxed

AMP-binding (462..859): ser

NRPSPredictor2: ser

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_27

Search NORINE for peptide: strict or relaxed

AMP-binding (34..437): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: AMPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

c00001_NZ_LSME.. - Region 2 - thiopeptide

Download region GenBank file

Download region SVG

Location: 351,546 - 377,854 nt. (total: 26,309 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Thiopeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.25	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.16	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.14	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001302.1	0.08	Other	lomofungin	Streptomyces lomondensis
BGC0000981.1	0.07	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0002012.1	0.07	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.07	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0001956.1	0.06	Polyketide	miharamycin A, miharamycin B	Streptomyces miharaensis
BGC0000957.1	0.06	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0000414.1	0.06	NRP	quinocarcin	Streptomyces melanovinaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.58	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.47	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.43	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001302.1	0.31	Other	lomofungin	Streptomyces lomondensis
BGC0000981.1	0.28	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0002012.1	0.28	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.27	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0001956.1	0.27	Polyketide	miharamycin A, miharamycin B	Streptomyces miharaensis
BGC0000957.1	0.24	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0000414.1	0.24	NRP	quinocarcin	Streptomyces melanovinaceus

Similar known gene clusters

Thiopeptide predictions

No core peptides found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

Thiopeptides

Core peptide predictions

No core peptides found.

c00006_NZ_LSME.. - Region 1 - RiPP-like

Download region GenBank file

Download region SVG

Location: 107,837 - 116,083 nt. (total: 8,247 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

No matches found.

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00023_NZ_LSME.. - Region 1 - butyrolactone

Download region GenBank file

Download region SVG

Location: 70,382 - 82,025 nt. (total: 11,644 nt) Show pHMM detection rules used

butyrolactone: AfsA

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001948.1	0.21	Other	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0000850.1	0.20	Other	γ-butyrolactone	Streptomyces acidiscabies
BGC0001310.1	0.20	Terpene	naringenin	Streptomyces clavuligerus ATCC 27064
BGC0000688.1	0.16	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000902.1	0.15	Other	flaviolin	Saccharopolyspora erythraea NRRL 2338
BGC0000285.1	0.15	Polyketide, Saccharide	flaviolin rhamnoside, 3,3'-diflaviolin, flaviolin	Saccharopolyspora erythraea
BGC0001783.1	0.14	Other	streptonigrin	Streptomyces flocculus
BGC0001374.1	0.14	Other	thienodolin	Streptomyces albogriseolus
BGC0002009.1	0.14	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0001140.1	0.13	Terpene	platensimycin, platencin	Streptomyces platensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001948.1	0.54	Other	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0000850.1	0.53	Other	γ-butyrolactone	Streptomyces acidiscabies
BGC0001310.1	0.53	Terpene	naringenin	Streptomyces clavuligerus ATCC 27064
BGC0000688.1	0.47	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000902.1	0.46	Other	flaviolin	Saccharopolyspora erythraea NRRL 2338
BGC0000285.1	0.44	Polyketide, Saccharide	flaviolin rhamnoside, 3,3'-diflaviolin, flaviolin	Saccharopolyspora erythraea
BGC0001783.1	0.43	Other	streptonigrin	Streptomyces flocculus
BGC0001374.1	0.43	Other	thienodolin	Streptomyces albogriseolus
BGC0002009.1	0.43	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0001140.1	0.42	Terpene	platensimycin, platencin	Streptomyces platensis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00034_NZ_LSME.. - Region 1 - arylpolyene

Download region GenBank file

Download region SVG

Location: 9,360 - 52,956 nt. (total: 43,597 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000836.1	0.50	Other	APE Ec	Escherichia coli CFT073
BGC0002008.1	0.50	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000837.1	0.34	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001444.1	0.30	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.28	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000228.1	0.26	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.26	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001723.1	0.24	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000679.1	0.22	Terpene	diazepinomicin	Micromonospora sp. M42
BGC0000266.1	0.22	Polyketide	collinomycin	Streptomyces collinus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000836.1	0.79	Other	APE Ec	Escherichia coli CFT073
BGC0002008.1	0.78	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000837.1	0.67	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001444.1	0.64	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.62	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000228.1	0.60	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001197.1	0.59	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001723.1	0.57	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000679.1	0.55	Terpene	diazepinomicin	Micromonospora sp. M42
BGC0000266.1	0.55	Polyketide	collinomycin	Streptomyces collinus

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names