LOCUS       NZ_CP007470.1          10948 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP007470.1 Haemophilus influenzae strain 477 chromosome, complete
            genome.
ACCESSION   NZ_CP007470
VERSION     NZ_CP007470.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:21:40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1473149
            Orig. end    :: 1484097
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10948
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1478149:1479097](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5948)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10948
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10948
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(934..1086)
                     /locus_tag="ctg1_1375"
                     /transl_table=11
                     /translation="MIAWRPFLAGKVTLTELNTAGLTDMGELLKINRLLDAVDAMEAKQ
                     MEKNR"
     CDS             complement(1122..1604)
                     /locus_tag="ctg1_1376"
                     /transl_table=11
                     /translation="MARSEIQIGESTFFVQKFSVMDQLRIFGDLQKTLVPSLAKVIGFS
                     DEKPKDATSAQLAELAQKSAANFAQGLQDLSQQLSGQELVKLADMLIKPELVTVQRDDF
                     NNGTDKKLSKTDFDLVFDDMSELIELVIFILQLNFSSFFTKFLARLGSVQELVKKA"
     CDS             complement(1604..2029)
                     /locus_tag="ctg1_1377"
                     /transl_table=11
                     /translation="MALATYAPDEVSIVIGAVIVSGFADGTFIDIEEMSDGVSSVAGAD
                     GEVARATSADPRKKVTLTLLQTSDTNDVLSELYAADKVSKNATFPIAVKDLRGRSLFAA
                     STAWVVKSAKLELGKEVGSREWTLETADGKLFVGGND"
     PFAM_domain     complement(1634..1948)
                     /aSDomain="DUF3277"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11681.10"
                     /description="Protein of unknown function (DUF3277)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1377_0051"
                     /evalue="9.80E-09"
                     /label="ctg1_1377"
                     /locus_tag="ctg1_1377"
                     /protein_end="132"
                     /protein_start="27"
                     /score="35.4"
                     /tool="antismash"
                     /translation="FIDIEEMSDGVSSVAGADGEVARATSADPRKKVTLTLLQTSDTND
                     VLSELYAADKVSKNATFPIAVKDLRGRSLFAASTAWVVKSAKLELGKEVGSREWTLETA
                     D"
     CDS             complement(2075..3148)
                     /locus_tag="ctg1_1378"
                     /transl_table=11
                     /translation="MAKIDRLVNVAIDLNTTTIAGKSFSDLLILGEHTLNNSARLLVVT
                     DPNELLDLGLKSNNPLYIAVATAFAQPSHVAQVFIGRKAQDESVTDALAAVARENNSWY
                     GLALVSREDADVMLAAAWAETNGKLFVTASADEKLPQSAEKTDIASKLEAKQYYRSAVM
                     YSHKATEEYPEIALMSYSFTFYPGSETWNLKKLAGVSYSPLMEGEYLACSKKNATTFEK
                     FNDSFAVTQGGKVAAGEWIDIIRFRDWLVQEVQINVTSVLINAYGKVPYTDKGIQLIGA
                     AVRQALDLGVARGGIAPTELDDNNKEIPSYVISLPLAAKVSNNNKGKRLLQDVKFSARL
                     AGAIHLTEIKGNLAYSL"
     PFAM_domain     complement(2093..2896)
                     /aSDomain="DUF3383"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11863.10"
                     /description="Protein of unknown function (DUF3383)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1378_0052"
                     /evalue="5.20E-51"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="352"
                     /protein_start="84"
                     /score="174.2"
                     /tool="antismash"
                     /translation="QDESVTDALAAVARENNSWYGLALVSREDADVMLAAAWAETNGKL
                     FVTASADEKLPQSAEKTDIASKLEAKQYYRSAVMYSHKATEEYPEIALMSYSFTFYPGS
                     ETWNLKKLAGVSYSPLMEGEYLACSKKNATTFEKFNDSFAVTQGGKVAAGEWIDIIRFR
                     DWLVQEVQINVTSVLINAYGKVPYTDKGIQLIGAAVRQALDLGVARGGIAPTELDDNNK
                     EIPSYVISLPLAAKVSNNNKGKRLLQDVKFSARLAGAIHLTEIKGN"
     CDS             complement(3135..3644)
                     /locus_tag="ctg1_1379"
                     /transl_table=11
                     /translation="MLERLYDLLGDLSDRPFIRAYENGREPEKPFFTYELKFERTPEHF
                     HYSAVNDEGNQTVKTHIDAVLELNYFGGNSLQALRDVCMRLSMQSCRERWLNDGVALIR
                     IGRITHLAFLNEQREYEDRAMVELEIRYAASVQDIVGIIEQVEVTANIGRASEKNLIGV
                     NKNGEN"
     CDS             complement(3646..4005)
                     /locus_tag="ctg1_1380"
                     /transl_table=11
                     /translation="MQIFSSQSSFRKPYKILVRSDGEYVKGKWVNDGEIEQTLMASIQP
                     LSSAEMDRLVVSMQGRRVSSAVKIYTDQKLTVAGENAHNVAVVLFDGERYEVISRASYH
                     SGVLSHHRYVAIRVK"
     CDS             complement(4005..4463)
                     /locus_tag="ctg1_1381"
                     /transl_table=11
                     /translation="VSSVVKVKINNKGLEKELELINKIGKARVKVGVQADAGIHSESGE
                     SLVDIGIWNEYGTAHIPSRPFIRQTFEDNQQALAQYLGRVVENVAKGDDLVQELSKLGQ
                     WYQDKQKKTLTSYPWTPNAPSTRRRKKSSKPLVDTSQLVNSIRYKVEI"
     CDS             complement(4456..4806)
                     /locus_tag="ctg1_1382"
                     /transl_table=11
                     /translation="MSAYSLLNLFYPLSQQMPEDMVNKVLSVADNKRPDCLSDEKQDEA
                     VAWYAAYLLAQSIESGVNAAGLRREREGDLEREYFSSSDKGGNAERFLAKYNELNNICV
                     RLGAITVGSHCV"
     PFAM_domain     complement(4552..4776)
                     /aSDomain="DUF4054"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13262.8"
                     /description="Protein of unknown function (DUF4054)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1382_0053"
                     /evalue="1.00E-07"
                     /label="ctg1_1382"
                     /locus_tag="ctg1_1382"
                     /protein_end="85"
                     /protein_start="10"
                     /score="32.0"
                     /tool="antismash"
                     /translation="YPLSQQMPEDMVNKVLSVADNKRPDCLSDEKQDEAVAWYAAYLLA
                     QSIESGVNAAGLRREREGDLEREYFSSSDK"
     CDS             complement(4810..4998)
                     /locus_tag="ctg1_1383"
                     /transl_table=11
                     /translation="MIVRNIEARLIRVGGEFIAPNQEVEIADDAVGLDRLIERGVLIDV
                     TPKAEDAKKDGKSKKQE"
     CDS             complement(5001..5948)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1384"
                     /sec_met_domain="Linocin_M18 (E-value: 6.8e-07, bitscore:
                     25.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDIRQDAFELNAIKTCLNAVGVFNQDAGLFTQRQLEFVRNKIYE
                     EKLPGMNGLSLVPVSSESPEWAETVTERIYDMVGMAKVVANYADDLPRADVAMTERAVK
                     VKNIGAAYGYNLQELKAASANQTDLPSSKARAARRAVEVKMNEIALLGDKEFGLNGFIN
                     HPNLGETSVTGGWKTATADAVLADLDNLHDTVVLQSKGVHQPTHLLLSLTDYQTLSSKY
                     MNTADKVDVLTFFKRKHPNLTIQGLWELEKAGTGNKNLAICYEKSLDNLTLETPQDFTQ
                     LPAQERNLELVVNCVARVGGVFLRYPLSATKAEI"
     PFAM_domain     complement(5010..5714)
                     /aSDomain="DUF2184"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09950.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2184)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1384_0054"
                     /evalue="7.60E-66"
                     /label="ctg1_1384"
                     /locus_tag="ctg1_1384"
                     /protein_end="313"
                     /protein_start="78"
                     /score="222.1"
                     /tool="antismash"
                     /translation="GMAKVVANYADDLPRADVAMTERAVKVKNIGAAYGYNLQELKAAS
                     ANQTDLPSSKARAARRAVEVKMNEIALLGDKEFGLNGFINHPNLGETSVTGGWKTATAD
                     AVLADLDNLHDTVVLQSKGVHQPTHLLLSLTDYQTLSSKYMNTADKVDVLTFFKRKHPN
                     LTIQGLWELEKAGTGNKNLAICYEKSLDNLTLETPQDFTQLPAQERNLELVVNCVARVG
                     GVFLRYPLSATKA"
     CDS             complement(6010..6429)
                     /locus_tag="ctg1_1385"
                     /transl_table=11
                     /translation="MSMYDQLQQKAFAGMKGDSRYDLVETFAAENEIPFGVVITQGTSA
                     TQAKLGGTKPIGITLHSHAVVGGYAKFDAVSVLRKGVAWCVVKDSEAITAGSAVSFDPA
                     SGKVAKTGTALPNATFKTAVVDCGKYGKLALVELA"
     CDS             complement(6442..7515)
                     /locus_tag="ctg1_1386"
                     /transl_table=11
                     /translation="MVMRYDRRGIQARRDDNGFIYDTPILTRSGVFVYELPNGKTRREY
                     RPPDEVFKADSLRAYKGLPITEDHHGLVTKNNAHLVVGSILTEGKQDGQNLTADIVIHN
                     TKAVDFGKKELSVGYKVDIDETSGITEDGEPYDVIQRNIRPNHLAIVTVGRAGNAALNL
                     DAADAVEFNEDGENPMSNTQTTLSDIRLDSGITYQAAPEVIVELNKLKQDAKDAVTAKD
                     KEAARADAAEAKVKELETQVEQIKQDAVSQAKVRVELENVAKVHKVEVKADSTDRALRE
                     AVIKAIRQDNADLSQKSDGYIEAAFDIAVSDAKQRADAAGVQRQQLTPSATNQPTFTQD
                     SQTKLTGRAAMIASRNQ"
     PFAM_domain     complement(7036..7476)
                     /aSDomain="DUF2213"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09979.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2213)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1386_0055"
                     /evalue="1.40E-31"
                     /label="ctg1_1386"
                     /locus_tag="ctg1_1386"
                     /protein_end="160"
                     /protein_start="13"
                     /score="109.9"
                     /tool="antismash"
                     /translation="RDDNGFIYDTPILTRSGVFVYELPNGKTRREYRPPDEVFKADSLR
                     AYKGLPITEDHHGLVTKNNAHLVVGSILTEGKQDGQNLTADIVIHNTKAVDFGKKELSV
                     GYKVDIDETSGITEDGEPYDVIQRNIRPNHLAIVTVGRAGNAA"
     CDS             complement(7641..8900)
                     /locus_tag="ctg1_1387"
                     /transl_table=11
                     /translation="MLKSIKKNRKPKVWLFPHAIEREYVGYLRGVARNINTMVNQKLVE
                     IRPHFQANIRQDSFSDTLERWLIELLQAVLIFVDEKEIAQFVRGYIHQTENFNGKQFHK
                     VLKSVYSVDVFTTEPWLDDALKIAEWENIRLIKSLPTQTLEKLRSRFTQAVRGGWRWES
                     VVDDVKSILNTNEKRATLIARDQIGKLNGHLTKLRQQNIGVKSYIWRGMLDERERAHHV
                     DREGKQFDWDNPPDDGHPGEPILCRCYAEAVFPEFEDLGRDDAEPIDPISTTKTGKMNL
                     DELFDNSLSGGGNKSFSNFGLVDPALVTLAKESIGLDISDWRHSIDESSIRHILKQHGN
                     EKAENKRGQRAVTKADILMLPQIVSSFDSIDYTGTSDAGSETFLLRKEIGDEIFCVQEV
                     RKRHKKIAVKTMWIRKKKKP"
     PFAM_domain     complement(7647..7970)
                     /aSDomain="PBECR3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18812.3"
                     /description="phage-Barnase-EndoU-ColicinE5/D-RelE like
                     nuclease3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1387_0057"
                     /evalue="1.40E-22"
                     /label="ctg1_1387"
                     /locus_tag="ctg1_1387"
                     /protein_end="418"
                     /protein_start="310"
                     /score="80.0"
                     /tool="antismash"
                     /translation="AKESIGLDISDWRHSIDESSIRHILKQHGNEKAENKRGQRAVTKA
                     DILMLPQIVSSFDSIDYTGTSDAGSETFLLRKEIGDEIFCVQEVRKRHKKIAVKTMWIR
                     KKKK"
     aSDomain        complement(8142..8453)
                     /aSDomain="TIGR01641"
                     /aSTool="tigrfam"
                     /description="phageSPP1_gp7: phage head morphogenesis
                     protein, SPP1 gp7 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1387_0016"
                     /evalue="5.40E-16"
                     /identifier="TIGR01641"
                     /label="ctg1_1387"
                     /locus_tag="ctg1_1387"
                     /protein_end="253"
                     /protein_start="149"
                     /score="56.9"
                     /tool="antismash"
                     /translation="RFTQAVRGGWRWESVVDDVKSILNTNEKRATLIARDQIGKLNGHL
                     TKLRQQNIGVKSYIWRGMLDERERAHHVDREGKQFDWDNPPDDGHPGEPILCRCYAEAV
                     "
     PFAM_domain     complement(8154..8465)
                     /aSDomain="Phage_Mu_F"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04233.16"
                     /description="Phage Mu protein F like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1387_0056"
                     /evalue="2.10E-15"
                     /label="ctg1_1387"
                     /locus_tag="ctg1_1387"
                     /protein_end="249"
                     /protein_start="145"
                     /score="57.5"
                     /tool="antismash"
                     /translation="KLRSRFTQAVRGGWRWESVVDDVKSILNTNEKRATLIARDQIGKL
                     NGHLTKLRQQNIGVKSYIWRGMLDERERAHHVDREGKQFDWDNPPDDGHPGEPILCRCY
                     "
     CDS             complement(8839..10155)
                     /locus_tag="ctg1_1388"
                     /transl_table=11
                     /translation="MAFNQDGYAEALGINHFARNSANSTALFDLTLYELGGLAARVVDM
                     PADAAISRSIEIQGDQDDAISNEIERLKILPALADMVRWSRFFGGAVMVLLTDDGARLS
                     EPLEPSRITRIDEVRVFDLSQISPTANRYSDPTKPNYGRYSSYRLNIGTIAGSLDSQVE
                     IHESRLLFMGGDSLPERLKNGLHWIGRSAVRSVYPKIRDYQKSLMWASLILERKQQAVH
                     KMKGLALAIDNGLEPVIRERINLVERGRSLLNGVAVDSEDDYNILNADLGGIVDVLDEF
                     KVAISADVNIPVAILFGQSAKGMNATGQSDFESYYDLVESIQQHKIKPVLEKLIELLMF
                     QKHIKSFENWKIKFPSLNTPTDKEIADVRKTNADAAKIELDRLINLVDSGALSTEELRT
                     QIAGEFGIQADKLPQVDDDDVEKYQEEQKAKGVVVSSRN"
     PFAM_domain     complement(9025..10068)
                     /aSDomain="DUF1073"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06381.13"
                     /description="Protein of unknown function (DUF1073)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1388_0058"
                     /evalue="3.70E-91"
                     /label="ctg1_1388"
                     /locus_tag="ctg1_1388"
                     /protein_end="377"
                     /protein_start="29"
                     /score="305.7"
                     /tool="antismash"
                     /translation="LTLYELGGLAARVVDMPADAAISRSIEIQGDQDDAISNEIERLKI
                     LPALADMVRWSRFFGGAVMVLLTDDGARLSEPLEPSRITRIDEVRVFDLSQISPTANRY
                     SDPTKPNYGRYSSYRLNIGTIAGSLDSQVEIHESRLLFMGGDSLPERLKNGLHWIGRSA
                     VRSVYPKIRDYQKSLMWASLILERKQQAVHKMKGLALAIDNGLEPVIRERINLVERGRS
                     LLNGVAVDSEDDYNILNADLGGIVDVLDEFKVAISADVNIPVAILFGQSAKGMNATGQS
                     DFESYYDLVESIQQHKIKPVLEKLIELLMFQKHIKSFENWKIKFPSLNTPTDKEIADVR
                     KTNADAAK"
ORIGIN
        1 gcttaccacc gattaccgta ccagctaaaa agcccactaa acgaatgttt tctgtcaccc
       61 attcagcagc attatagaaa gccgcgccga gtttagagac tttattgacc gccacatcaa
      121 tcaattgacc ggctttattt ttcagaatcg tcataccgcg cccaaaagtt ttcggcatct
      181 gatcgaattc tttttggatt ttatccgctt gttttagcag accttgtgcg agttcttttg
      241 atgtgagctt accttcttta cctagatctt ttaattgccc aatcggcacg ccaaaactat
      301 cagcaatggc attcgctaaa cgtggggctt gttcaataat tgagttcagc tcatcgccac
      361 gtaatgcacc cgagcctaag gcttgaccaa gctgcatcaa ggcggcttgc tgcgccccct
      421 gatcgccgcc gccaatcgtc atcgtttgcc caatgatttc cgttaaattt aacgtatcat
      481 caagacttaa ccccaaatcc cccgcacttc gattcacttt tgagaataaa tctgcactgg
      541 cgagatagtc ttgtccggaa cgttgtgaaa ggtcgaaaat ctgactcaat gcatatttat
      601 gttcttcagc ggattttgtc gctaatttca cacgactatc caccgcagcc cattcatcgg
      661 caattttgat cgcactacca ccggcaacca tcgcaaaata accaccaaca aggttacgta
      721 gagaaagcat ttgattttta gcgtctttca gattattacc gacctctttc acgctcacgg
      781 cagcccctga gaatttagcg cgtaatccat cgactgcatt attcaggttg ctacgaatgc
      841 cttttgccgc ctgttgagtt tgaacaacat aagcctttaa accggaatta tcgactttat
      901 aacgcaataa cgttaccagc tcacgtatag cattcatcgg tttttctcca tttgttttgc
      961 ttccatcgca tctaccgcat ctagtaagcg attaatcttc aaaagctcgc ccatatccgt
     1021 caatcctgcc gtattaagct ctgttagtgt aactttaccg gctaaaaaag gacgccaagc
     1081 gatcatctca cttagcgtct gttcgctgta tttaccaacg cttacgcttt cttcacaagc
     1141 tcttgcaccg acccaagacg ggcaagaaat ttcgtaaaaa aactgctgaa attaagttgt
     1201 aagatgaaaa ttaccaactc gataagctcc gacatatcat caaacaccaa atcaaaatca
     1261 gttttgctaa gttttttatc tgtcccattg ttgaaatcat cacgctgcac cgtcactagt
     1321 tcaggtttga ttagcatatc agctagttta actaactctt ggccgcttaa ttgctggctt
     1381 aaatcttgta aaccttgtgc aaaattcgcc gcacttttct gtgctaattc ggctaactga
     1441 gctgacgttg catctttcgg tttttcatcg ctaaatccga ttactttcgc cagtgacggt
     1501 acaagggttt tctgcaaatc gccaaaaatg cgtaactgat ccattaccga aaacttttgc
     1561 acaaaaaaag tgctttcgcc aatttgaatt tcactgcgtg ccatcagtca tttcccccta
     1621 caaataattt accgtccgca gtttcaagcg tccactcgcg agaacccact tcttttccaa
     1681 gctcaagttt cgccgattta accacccacg ccgtgcttgc agcgaataat gagcgaccac
     1741 gcaagtcttt taccgcaatt ggaaaggttg cgtttttact cactttatcc gctgcataga
     1801 gttcacttaa cacatcattg gtatcactgg tttgtaataa cgttaatgtg acttttttac
     1861 gtggatcggc actggttgca cgtgctactt cgccatctgc accagcaaca gatgatacgc
     1921 cgtcagacat ttcttcaata tcaataaagg ttccatctgc aaagccagaa acaataaccg
     1981 ccccgatcac aatacttact tcatcgggcg cataagttgc taaagccata aaattctcct
     2041 aaaaaatgac cgcactttag cggtctgtta atgattaaag actgtaagcc agattgccct
     2101 tgatttctgt taagtgaata gcaccggcta aacgtgccga gaatttcaca tcttgcaata
     2161 aacgcttacc tttattgtta ttcgatacct ttgccgccag tggaagggaa atcacataac
     2221 ttggaatttc cttgttatta tcatccaatt ctgtcggcgc aataccgcca cgtgctacac
     2281 ctaaatctaa cgcctgacgc actgctgcac caattaattg aataccttta tcggtgtaag
     2341 gcactttgcc gtaagcattg attaagacgg atgtcacatt aatttgtact tcctgcacca
     2401 accaatcacg gaaacggata atatcgatcc attccccagc tgcgactttg ccgccttgcg
     2461 ttaccgcaaa gctatcgtta aatttctcaa atgtcgttgc gtttttcttc gagcaagcta
     2521 agtattcgcc ttccattaac ggcgaataag atacgccagc aagttttttc aagttccacg
     2581 tttctgaccc cggatagaat gtgaaggaat agctcattaa ggcaatttct gggtattctt
     2641 ccgttgcttt atgggaatac attaccgccg agcggtaata ttgtttcgct tcaagtttgc
     2701 tcgcaatatc ggttttctcc gccgattgtg gcaatttttc atcagcagag gcggtaacaa
     2761 ataatttacc attggtttct gcccacgccg ccgccaacat cacatcagcg tcttcacgcg
     2821 agaccaacgc caagccatac cagctgttat tttctcgtgc gaccgcagca agcgcatccg
     2881 tcacgctttc atcttgtgct ttacgtccga taaatacctg tgccacgtgt gacggctgcg
     2941 caaaggcggt agccacagcg atataaagcg gattgtttga ttttaagcct aaatccaata
     3001 attcatttgg atcggtgact accagcaaac gtgctgaatt attcagcgta tgttcgccta
     3061 aaattaataa atcactaaaa gatttaccgg cgattgtggt tgtatttaaa tcaatagcca
     3121 catttaccaa gcgatcaatt ttcgccattt ttatttaccc ctattaaatt tttctcagaa
     3181 gcacgtccta tatttgccgt cacttccact tgttcaataa tacccacaat atcctgcaca
     3241 ctagccgcat aacgaatttc aagctctacc attgcccgat cttcatattc acgctgttca
     3301 tttagaaagg ctaaatgggt aatccgccca atgcgaatca atgccacgcc atcatttaac
     3361 caacgctcac gacaagactg catagataag cgcatacaaa catctcgcaa tgcctgtaaa
     3421 ctgtttccac cgaaataatt caactcaagc acggcatcga tatgagtttt taccgtctga
     3481 ttgccttcat catttaccgc cgaataatga aaatgttctg gtgtcctctc aaacttcagt
     3541 tcataagtaa aaaatggctt ttctggctca cgcccatttt cataggcgcg aataaaaggg
     3601 cgatccgata gatcgcccaa taaatcatac aaacgctcaa gcatattatt ttacccgtat
     3661 agccacgtag cgatgatgtg acaacacacc actgtgataa ctagctcgtg aaatcacttc
     3721 gtatcgctcg ccgtcaaata gcactactgc gacattgtgt gcattttctc cagccaccgt
     3781 tagtttttga tcggtgtaaa tttttaccgc acttgaaacg cgccgcccct gcattgatac
     3841 cactaggcga tccatttcag cactgcttaa cggctgaatg gatgccatta acgtctgctc
     3901 gatttcgccg tcgtttaccc acttgccttt cacatactct ccgtcagaac gcacaagtat
     3961 tttataaggc ttgcgaaaag aagattgaga agaaaatatc tgcatcagat ttcaacctta
     4021 taacgaattg aattgactaa ttgcgaggta tctacgagcg gtttactact tttcttgcgc
     4081 ctacgcgtag atggtgcatt cggtgtccaa ggataagacg ttagggtctt tttctgcttg
     4141 tcttgatacc attgcccaag ttttgaaagc tcttgcacca aatcatcccc tttcgccaca
     4201 ttctcgacca cacgccctaa gtattgcgcc aatgcctgtt ggttgtcttc aaaggtttga
     4261 cgaataaaag gacgagacgg gatatgtgcc gtgccatatt cattccaaat accgatatcc
     4321 accaagcttt cgcctgattc agaatgaatg cctgcatccg cttgaacgcc tacttttacg
     4381 cgtgctttgc cgattttgtt tatcaactca agttcttttt caagcccttt attgttgatt
     4441 tttaccttaa ccacgctaga cacaatgact ccctacggta atcgcaccaa ggcgcacgca
     4501 aatattgttt agctcgttat acttcgccaa aaagcgttca gcgttgccgc ctttatcgct
     4561 gcttgaaaaa tattcacgtt ctaaatcgcc ctcacgttca cgtcgtaaac ctgccgcatt
     4621 taccccgctt tcaatcgact gagccaacaa ataagccgca taccacgcca ccgcctcatc
     4681 ttgcttttca tcagataaac agtctggacg tttattatca gccacgctta acaccttatt
     4741 taccatatct tcaggcattt gttggcttaa tgggtaaaag agattaagta acgagtatgc
     4801 gctcatttat tactcctgct ttttactttt gccgtctttt ttcgcatctt ccgctttcgg
     4861 cgttacgtca attaatacgc cacgttcaat taaacgatca agccctaccg catcatcggc
     4921 aatttccacc tcttgattag gggcgataaa ctcgccgcca acacgaatta aacgcgcttc
     4981 aatattacgt acaatcatcg ctaaatctcc gctttggttg ccgataacgg ataacgtaag
     5041 aacacgccgc ccacacgagc cacacagttc acaacaagct ctaaattgcg ttcttgtgcc
     5101 ggtaactggg taaaatcttg cggagtttca agagttaagt tatcaaggga tttttcatag
     5161 caaatcgcta agttcttatt ccctgtaccc gctttctcta attcccataa gccctgaata
     5221 gttaagttag gatgtttacg cttgaagaac gtcaatacgt ccactttgtc agccgtgttc
     5281 atatacttac tggataacgt ctgataatct gttagcgaca acaataagtg tgttggctga
     5341 tgcacgcctt ttgattgcaa cacgacggta tcgtgtagat tgtccaaatc cgctagcacc
     5401 gcatccgccg ttgcagtttt ccagccacca gttaccgagg tttctcctaa attcgggtgg
     5461 ttaataaagc cgtttaaacc aaattcttta tctcctaaca aggcaatttc gttcatcttt
     5521 acttccaccg cacgacgcgc tgcacgagct ttagaagacg gtaaatccgt ttgattagct
     5581 gacgccgctt tcaactcttg tagattgtag ccataagcag caccgatgtt tttcactttt
     5641 actgcacgtt ctgtcatcgc cacatccgca cgcggtaaat catcggcata gttggcaacg
     5701 actttagcca tgccgaccat atcgtaaatg cgttcagtca cggtttctgc ccattcaggg
     5761 gattcagaag agactgggac gagcgataag ccattcatac ccggtaattt ttcttcatag
     5821 attttgttgc gcacaaactc taattggcgt tgcgtaaaca agcccgcatc ttggttaaat
     5881 acacccaccg catttaaaca agtcttaatc gcattcaact caaatgcatc ttgacgaata
     5941 tctgtcatta tttttctcca ataaaaaagc cccaagtttt cacttagggc atcgttaaac
     6001 attgaataat taagctaact cgactaatgc gagcttgcca tatttaccgc aatccactac
     6061 ggcggtttta aaggttgcat tcggtaatgc cgtaccagtt tttgccacct tgcctgaagc
     6121 ggggtcaaaa cttaccgcac ttcctgccgt aatagcttcg ctgtctttca ctacacacca
     6181 cgcaacccct ttacgcaata cggaaaccgc atcaaatttc gcataaccgc ctactacagc
     6241 atgggaatgt aacgtaatgc caatgggctt agtgccacct aatttagctt gtgtggcact
     6301 cgtcccttgc gtaatcacta cgccgaatgg gatttcattt tctgctgcaa aggtttcgac
     6361 taaatcgtaa cggctgtcgc ctttcatacc agcaaaggct ttttgttgta attgatcgta
     6421 catagacatc gttttatgct cctattggtt acgacttgca atcattgccg cacgaccagt
     6481 taatttcgtt tggctatcct gcgtgaatgt gggttgattt gtggctgatg gtgttaattg
     6541 ctgacgctgc acacctgccg catccgctct ttgtttggca tcgcttaccg caatatcaaa
     6601 cgccgcttca atataaccat cggatttttg cgataaatcc gcattgtctt gacgaattgc
     6661 cttaatcaca gcctcacgca acgcacggtc ggtactatca gctttcactt ccaccttatg
     6721 cactttcgct acgttttcca attcaacacg caccttggct tgacttaccg catcttgttt
     6781 aatttgttca acctgcgttt caagctcttt cactttcgct tctgccgcat ctgcgcgtgc
     6841 cgcttctttg tcttttgctg tcactgcgtc tttggcgtct tgttttagtt tatttaattc
     6901 aacaatcact tcgggtgcgg cttgatacgt aatgccgcta tctaagcgaa tgtcagaaag
     6961 cgttgtttga gtgttactca tcggattttc tccatcttcg ttaaattcca cggcatctgc
     7021 cgcatctaaa ttaagtgcgg cattgcctgc acgcccaact gtcacaatgg ctaaatggtt
     7081 aggacgaata ttacgctgga tcacatcata cggctcgccg tcttctgtta taccgctcgt
     7141 ctcgtcaata tctaccttat agccaaccga caattctttt tttccaaaat caacggcttt
     7201 cgtattgtgg atcacaatat ctgccgttaa attttgccca tcttgtttac cttccgttaa
     7261 gatagagccc accaccaaat gcgcattatt tttcgtcaca agtccgtgat gatcttctgt
     7321 aatcggcaat cccttgtaag cgcgtaaact atccgcctta aatacttcat caggcggacg
     7381 atattcacgc cgagttttgc cattaggaag ctcataaaca aacaccccac ttcttgtcag
     7441 aataggggtg tcataaataa aaccgttatc atctcgccgt gcctgaatgc cacggcggtc
     7501 gtatcgcatt accatataat gatctccaaa aattgaaatt taaattcaat gctctataat
     7561 acagaaaacc ataaatcgta ggacatagca cgtttcggac gttaagcagg tgccagagtg
     7621 aaccaagcac tatgtgagat ttatggtttt ttctttttcc gaatccacat tgtttttact
     7681 gcaattttct tatggcgttt tctaacttct tgaacgcaaa agatttcatc tccaatttct
     7741 ttgcgtagta aaaacgtttc acttcccgca tcacttgtcc cagtgtagtc aatactatca
     7801 aatgacgaaa caatctgcgg caacatcaaa atatcggctt ttgttaccgc tctttgccca
     7861 cgcttatttt cagctttctc atttccgtgt tgctttagaa tatggcgtat actcgattca
     7921 tcaatgctat gccgccaatc gcttatatct aatccaatac tttctttagc aagtgtaact
     7981 aaggcaggat caaccaaacc aaaattagaa aatgacttat ttccaccacc ggataatgaa
     8041 ttatcaaaca actcatctaa gttcattttc cctgttttgg ttgttgaaat aggatctatc
     8101 ggttcagcgt catctctccc aagatcttca aattcaggga ataccgcctc cgcatagcaa
     8161 cgacataaaa taggctcccc cggatgtccg tcatcaggtg gattatccca atcaaattgt
     8221 ttaccctcac gatcaacgtg gtgcgcccgc tcacgctcat caagcatacc gcgccaaata
     8281 tacgacttca cgccgatatt ttgctggcgc aacttcgtca aatgaccgtt taacttgcca
     8341 atttggtcac gagcaattaa tgttgcacgt ttctcgttgg tgttaaggat agacttcaca
     8401 tcatctacca cgctttccca acgccaacca ccgcgcaccg cttgagtaaa gcgactacgc
     8461 aatttttcta acgtctgcgt aggaaggctt tttattaggc ggatattttc ccattccgca
     8521 atttttaacg catcatcaag ccaaggttca gtcgtgaaaa catcgacgct ataaactgat
     8581 ttcagcactt tgtgaaactg cttgccgtta aagttctccg tctgatgaat atagccacgc
     8641 acaaattgcg caatttcttt ttcatcaaca aaaatcaata ccgcttgcaa taattcaata
     8701 agccaacgtt caagtgtatc agaaaaacta tcttgtcgaa tatttgcctg aaagtgcggt
     8761 cgaatttcaa cgagtttttg attaaccatc gtattaatgt ttctcgccac accacgtaaa
     8821 taacccacat attcacgctc aattgcgtga ggaaacaacc acacctttgg ctttctgttc
     8881 ttcttgatac ttttcaacat catcgtcatc tacctgtggc aatttgtccg cttgaatgcc
     8941 aaactccccg gcaatctgtg ttcgcaattc ttctgtggat aatgcacccg aatcaaccaa
     9001 attaattaac cgatcaagct caattttcgc tgcatccgca ttcgttttac gcacatcggc
     9061 tatttctttg tcagttggtg tattaagcga cgggaatttg attttccagt tctcaaacga
     9121 cttaatatgc ttttgaaaca tcaatagttc aatcagcttt tcaagcactg gcttgatttt
     9181 atgttgttga atactttcga ccaaatcgta atagctttca aaatcgctct gccctgtggc
     9241 gttcatacct ttagctgact gcccgaataa aatcgccact ggaatattca catcagccga
     9301 aatcgctact ttaaattcat caagcacatc aacaatcccg cctaaatccg cattgagaat
     9361 gttgtaatcg tcttcgctat caacagctac gccatttaac agactacgcc cacgttcaac
     9421 aagattgata cgctctcgaa taacaggctc taatccatta tcaattgcca acgcaagccc
     9481 tttcatttta tgaaccgctt gctgtttgcg ttcaagaatt aacgaagccc acatcaatga
     9541 tttttgataa tcacgaattt ttggataaac cgatctaacc gcactacgcc caatccaatg
     9601 taagccattt tttagacgtt ctggcaatga atcgccgccc ataaataaca aacggctttc
     9661 atggatttct acctgactat caagcgaacc agcaatcgta ccgatattta accgataact
     9721 ggaatagcga ccataattcg gcttggttgg atcggaatag cgattagccg taggcgaaat
     9781 ttgacttaaa tcaaacactc gcacttcatc gatacgtgta atgcgacttg gctctaacgg
     9841 ttcacttaat cgcgcaccgt catcggtcaa taaaaccata accgcaccac caaaaaaccg
     9901 cgaccaacgc accatatctg ccaatgctgg caaaatcttc aaccgttcaa tctcattgct
     9961 aatcgcatca tcttgatcgc cttgaatttc aatcgaacgt gaaatcgccg catctgctgg
    10021 catatcgacc acccgtgcgg ctaaaccacc taactcatat aacgttaaat caaaaagtgc
    10081 ggttgaattt gcagaatttc ttgcaaaatg attaatcccc aaggcttcgg cgtagccgtc
    10141 ttgattaaat gccatattaa cttcctaacc caatgaaacg cgacaataca tcttctttcg
    10201 gtgcgaaaca cattaccaac gcatccgcct tattcggtga cggaatgcca cgctttttca
    10261 tatctttctt actttctact tttacacgcc cattaccgtc ataatccaca taagggcgtg
    10321 ccaattctgc tcttaaatat tccaaatccc ttatatcgga agaaagacta atcatttcat
    10381 caacgggata ttgctcttca tacgtgatcg cccgataggt tttatagaaa cgatcgcgca
    10441 aacgccacca cgcctgagcc ttaatattgg cgaacatatc tcgattggtt ttaccataaa
    10501 tatattctgc atcaggttca aataccgagc ctccagcatt aaagccatta atacgaatgg
    10561 atttatcgtt taggcgatga tagtgcgctt ttacaccggc acccacgccg atgctatcgt
    10621 aaacaatttc atttgcgcca aattccaatg cattaagccg agttctgtct gcactaccaa
    10681 tcacatcttc gccgcgccat tcatccattc gcaacactac agaaccatga acaaaggcat
    10741 tagcattcgc atctgagcct tcatccgcca catcaaaacc aataatcttt cgtcctgctg
    10801 ccacaaagcc tagtttttta tgtgcatcaa ccgcggcatc aatccacaat ggtttaataa
    10861 taaccttatc gctatcagct accggttctc cctcataaac atgacgataa agctcgtaat
    10921 cacgctctcg catctgcgcc atatcttc
//
