LOCUS       NZ_CP007470.1           7857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP007470.1 Haemophilus influenzae strain 477 chromosome, complete
            genome.
ACCESSION   NZ_CP007470
VERSION     NZ_CP007470.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:21:40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 484822
            Orig. end    :: 492679
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..165)
                     /locus_tag="ctg1_458"
                     /transl_table=11
                     /translation="MPWIETDAMQQRVLFLKAWLSQRYTKTELCQQFNISRPTVDKWIK
                     RHQQLGFEG"
     protocluster    1..7857
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[486804:487728](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1983..2906)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..7857
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     complement(4..144)
                     /aSDomain="HTH_23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13384.8"
                     /description="Homeodomain-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_458_0041"
                     /evalue="7.40E-10"
                     /label="ctg1_458"
                     /locus_tag="ctg1_458"
                     /protein_end="54"
                     /protein_start="7"
                     /score="38.5"
                     /tool="antismash"
                     /translation="AMQQRVLFLKAWLSQRYTKTELCQQFNISRPTVDKWIKRHQQLGF
                     EG"
     CDS             complement(1277..1993)
                     /locus_tag="ctg1_459"
                     /transl_table=11
                     /translation="MQPKSLLKETQQALANAIRLGNADPLNGYAANRLAVYTRLVRNNA
                     FGFIDRCFVEAPLHIEPEYWKNAKENFVQNGNAHSPYFQDIAGEFLLFCQEKEIFDANI
                     LALMDFENTQLLAEVSLAKVPEKFEWDRHSVMQLSGAAYLKSYEVDFLSSDFKQFDDTP
                     IQVIIWRDSDFRIQQQILSELDYWLLSYLQEQPNSLENVLSALNTMVEDSTSIIPLLEQ
                     VWMKWVTSEVIYPEQR"
     PFAM_domain     complement(1712..1969)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_459_0042"
                     /evalue="8.80E-15"
                     /label="ctg1_459"
                     /locus_tag="ctg1_459"
                     /protein_end="94"
                     /protein_start="8"
                     /score="54.8"
                     /tool="antismash"
                     /translation="ETQQALANAIRLGNADPLNGYAANRLAVYTRLVRNNAFGFIDRCF
                     VEAPLHIEPEYWKNAKENFVQNGNAHSPYFQDIAGEFLLFC"
     CDS             complement(1983..2906)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_460"
                     /sec_met_domain="DUF692 (E-value: 2e-136, bitscore: 450.2,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLQGAGLGYRRNLAEDFLQLPPNNAIQFIEVAPENWSKMGGMAR
                     YQFDQAAERFPLAVHGLSLSLGGQAPLDRKLLRNTKALMNQYNSSFFSEHLSYCECEGH
                     LYDLLPMPFTEEAVKHVAQRIRDVQDFLGLQISLENTSYYLHSPTSTMNEVEFLNAIAQ
                     EANCGIHLDVNNIYVNGVNHGLLDPYVFLDQVDVKRVNYIHIAGHDEEHSAAQVVENSA
                     DESFNKVKGAYRHLPELLIDTHGEAVKGTVWDLLEYAYQRLPTIPPTLLERDFNFPPFA
                     ELYAEVEHIAQLQQKYAHTEVMSYAA"
     PFAM_domain     complement(2022..2894)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_460_0043"
                     /evalue="5.00E-99"
                     /label="ctg1_460"
                     /locus_tag="ctg1_460"
                     /protein_end="295"
                     /protein_start="4"
                     /score="330.9"
                     /tool="antismash"
                     /translation="GAGLGYRRNLAEDFLQLPPNNAIQFIEVAPENWSKMGGMARYQFD
                     QAAERFPLAVHGLSLSLGGQAPLDRKLLRNTKALMNQYNSSFFSEHLSYCECEGHLYDL
                     LPMPFTEEAVKHVAQRIRDVQDFLGLQISLENTSYYLHSPTSTMNEVEFLNAIAQEANC
                     GIHLDVNNIYVNGVNHGLLDPYVFLDQVDVKRVNYIHIAGHDEEHSAAQVVENSADESF
                     NKVKGAYRHLPELLIDTHGEAVKGTVWDLLEYAYQRLPTIPPTLLERDFNFPPFAELYA
                     EVEHIAQLQQ"
     CDS             complement(2967..3254)
                     /locus_tag="ctg1_461"
                     /transl_table=11
                     /translation="MKKLATLTALASALTMAVATAVQAESKSSNTDNTATPCVGDKCVK
                     TKAAEGKCGEGKCGADKAKSAEGKCGEGKCGASKPKAAEGKCGEGKCGSK"
     CDS             complement(3293..3733)
                     /locus_tag="ctg1_462"
                     /transl_table=11
                     /translation="MQGIGSGVSLLILRFFLAWEFFEAGLEKWNGQNWFAEIQDRFPFP
                     FNLIPADINWHVAMGSELIFPFLLIFGVLTRFSALSLTILISVAWYSIHADSGYNVCDN
                     GYKLPLIYVVTLLILITQGAGKLSLDTLIKKVYPTKSWLKFL"
     PFAM_domain     complement(3452..3706)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_462_0044"
                     /evalue="5.90E-20"
                     /label="ctg1_462"
                     /locus_tag="ctg1_462"
                     /protein_end="94"
                     /protein_start="9"
                     /score="71.8"
                     /tool="antismash"
                     /translation="LLILRFFLAWEFFEAGLEKWNGQNWFAEIQDRFPFPFNLIPADIN
                     WHVAMGSELIFPFLLIFGVLTRFSALSLTILISVAWYSIH"
     CDS             3956..4636
                     /locus_tag="ctg1_463"
                     /transl_table=11
                     /translation="MAMNNILGLFAHSPLKPLQKHSEKVTECSDLLIPFFQTTFSKNWE
                     QAEEKRLEISQCEREADSLKREIRLKLPRGLFLPIDRTDLLELVTQQDKLANYAKDIAG
                     RMIGRQFGIPEEMQEEFLHYVKRSLDAIHQAHRVIEEMDKLLETGFKGRELKLVNDMIQ
                     ELDLIEDDTDQMQIKLRKMLYTIESRYNPIDVMFLYKIIEWVGVLADQAQRVGSRIELM
                     LARS"
     aSDomain        3962..4633
                     /aSDomain="TIGR00153"
                     /aSTool="tigrfam"
                     /description="TIGR00153: TIGR00153 family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_463_0014"
                     /evalue="5.30E-91"
                     /identifier="TIGR00153"
                     /label="ctg1_463"
                     /locus_tag="ctg1_463"
                     /protein_end="226"
                     /protein_start="2"
                     /score="302.1"
                     /tool="antismash"
                     /translation="MNNILGLFAHSPLKPLQKHSEKVTECSDLLIPFFQTTFSKNWEQA
                     EEKRLEISQCEREADSLKREIRLKLPRGLFLPIDRTDLLELVTQQDKLANYAKDIAGRM
                     IGRQFGIPEEMQEEFLHYVKRSLDAIHQAHRVIEEMDKLLETGFKGRELKLVNDMIQEL
                     DLIEDDTDQMQIKLRKMLYTIESRYNPIDVMFLYKIIEWVGVLADQAQRVGSRIELMLA
                     RS"
     PFAM_domain     3974..4627
                     /aSDomain="PhoU_div"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01865.18"
                     /description="Protein of unknown function DUF47"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_463_0045"
                     /evalue="4.70E-85"
                     /label="ctg1_463"
                     /locus_tag="ctg1_463"
                     /protein_end="224"
                     /protein_start="6"
                     /score="284.4"
                     /tool="antismash"
                     /translation="LGLFAHSPLKPLQKHSEKVTECSDLLIPFFQTTFSKNWEQAEEKR
                     LEISQCEREADSLKREIRLKLPRGLFLPIDRTDLLELVTQQDKLANYAKDIAGRMIGRQ
                     FGIPEEMQEEFLHYVKRSLDAIHQAHRVIEEMDKLLETGFKGRELKLVNDMIQELDLIE
                     DDTDQMQIKLRKMLYTIESRYNPIDVMFLYKIIEWVGVLADQAQRVGSRIELMLA"
     CDS             4661..5923
                     /locus_tag="ctg1_464"
                     /transl_table=11
                     /translation="MEIISQYGSWLVWITAAFGFFMAFGIGANDVSNSMGTSVGSGTVT
                     AKQAIIIALIFESAGAYLAGGEVTQTIKSGVIDPMQFVDTPDILALGMLSTLFASGAWL
                     FIATKMGWPVSGIHTIIGAIIGFACITIGPSSVDWSNIGSIVGSWFVTPVISGILAYAI
                     FASTQKLIFDTEQPLKNAQKYGPYYMGITMFVLCIVTMKKGLKHVGLNLSNSETLIISL
                     AISLIGMFFFHFYFKSKTFTQSASKGTFVAVEKVFSILMLLTACAMAFAHGSNDVANAI
                     GPLSAVVSIVNEGGKIVSGGALTWWILPLGALGIAVGLITMGQKVMATVGSGITDLTPS
                     RGFAAQFATAMTVVVASGTGLPISTTQTLVGAILGIGFARGIAALNLTVIRNIISSWIV
                     TLPAGAFFAIIIFYVLRTIFN"
     PFAM_domain     4736..5881
                     /aSDomain="PHO4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01384.22"
                     /description="Phosphate transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_464_0046"
                     /evalue="4.50E-106"
                     /label="ctg1_464"
                     /locus_tag="ctg1_464"
                     /protein_end="407"
                     /protein_start="25"
                     /score="355.0"
                     /tool="antismash"
                     /translation="IGANDVSNSMGTSVGSGTVTAKQAIIIALIFESAGAYLAGGEVTQ
                     TIKSGVIDPMQFVDTPDILALGMLSTLFASGAWLFIATKMGWPVSGIHTIIGAIIGFAC
                     ITIGPSSVDWSNIGSIVGSWFVTPVISGILAYAIFASTQKLIFDTEQPLKNAQKYGPYY
                     MGITMFVLCIVTMKKGLKHVGLNLSNSETLIISLAISLIGMFFFHFYFKSKTFTQSASK
                     GTFVAVEKVFSILMLLTACAMAFAHGSNDVANAIGPLSAVVSIVNEGGKIVSGGALTWW
                     ILPLGALGIAVGLITMGQKVMATVGSGITDLTPSRGFAAQFATAMTVVVASGTGLPIST
                     TQTLVGAILGIGFARGIAALNLTVIRNIISSWIVTLPAGAFF"
     CDS             5989..6600
                     /locus_tag="ctg1_465"
                     /transl_table=11
                     /translation="MKKIYKALISSLLLSTSINVAYAETQYVTENLSTFLRRGAGEQFK
                     IAGSIQAGEAVNVLDRQGKYTLIRDNKNREAWILNSDLSSTPSSKEENPKLKAQVQELT
                     LKLSRLDGDWQQRTVEMQRRTKQAEQQSADLLEQNSQLKRELEMTKNKNRDLEAILDAG
                     KREIAIQWFIYGGSVLGVGLLFGLLIPYVLPKRRRRDGWA"
     aSDomain        6067..6594
                     /aSDomain="TIGR04211"
                     /aSTool="tigrfam"
                     /description="SH3_and_anchor: SH3 domain protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_465_0015"
                     /evalue="1.10E-45"
                     /identifier="TIGR04211"
                     /label="ctg1_465"
                     /locus_tag="ctg1_465"
                     /protein_end="202"
                     /protein_start="26"
                     /score="153.6"
                     /tool="antismash"
                     /translation="YVTENLSTFLRRGAGEQFKIAGSIQAGEAVNVLDRQGKYTLIRDN
                     KNREAWILNSDLSSTPSSKEENPKLKAQVQELTLKLSRLDGDWQQRTVEMQRRTKQAEQ
                     QSADLLEQNSQLKRELEMTKNKNRDLEAILDAGKREIAIQWFIYGGSVLGVGLLFGLLI
                     PYVLPKRRRRDGW"
     PFAM_domain     6091..6240
                     /aSDomain="SH3_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08239.13"
                     /description="Bacterial SH3 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_465_0047"
                     /evalue="1.30E-07"
                     /label="ctg1_465"
                     /locus_tag="ctg1_465"
                     /protein_end="84"
                     /protein_start="34"
                     /score="32.0"
                     /tool="antismash"
                     /translation="FLRRGAGEQFKIAGSIQAGEAVNVLDRQGKYTLIRDNKNREAWIL
                     NSDLS"
     CDS             6607..7857
                     /locus_tag="ctg1_466"
                     /transl_table=11
                     /translation="MKIYLVGGAIRDQLLGLPVKDRDWIVVGADPATLLSLGYQQVGKD
                     FPVFLNPKTKEEYALARTERKSSTGYTGFICDFSPTITLEQDLIRRDLTINAMAQSEDG
                     EIIDPYGGKQDLENRILRHISPAFSEDPLRVLRVARFAARYHSLGFKIASETLSLMAEL
                     ALSGELQHLTAERVWLETEKALNEKNPEIYFETLHKTGALSVLFPEIDALYGVPNPVKH
                     HPEVDSFIHTMLVLKQAVNLTENNPILNKSAVRFAAICHDLGKALTPQNILPHHYGHEQ
                     AGIKPTRSLCKRLKVPSYFQELAELTCEFHTHIHKAFELRAETVITLFNRFDVWRKSQR
                     FQEFLQVCLADTRGRTGFENKDYPQIDYINQLLHAANEVDVQQVIADGFEKQAIKNELT
                     KRRILAVKQTKTNYPTN"
     PFAM_domain     6613..6972
                     /aSDomain="PolyA_pol"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01743.22"
                     /description="Poly A polymerase head domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_466_0048"
                     /evalue="3.80E-18"
                     /label="ctg1_466"
                     /locus_tag="ctg1_466"
                     /protein_end="122"
                     /protein_start="2"
                     /score="66.2"
                     /tool="antismash"
                     /translation="IYLVGGAIRDQLLGLPVKDRDWIVVGADPATLLSLGYQQVGKDFP
                     VFLNPKTKEEYALARTERKSSTGYTGFICDFSPTITLEQDLIRRDLTINAMAQSEDGEI
                     IDPYGGKQDLENRILR"
     PFAM_domain     7051..7242
                     /aSDomain="PolyA_pol_RNAbd"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12627.9"
                     /description="Probable RNA and SrmB- binding site of
                     polymerase A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_466_0049"
                     /evalue="3.70E-15"
                     /label="ctg1_466"
                     /locus_tag="ctg1_466"
                     /protein_end="212"
                     /protein_start="148"
                     /score="55.5"
                     /tool="antismash"
                     /translation="GFKIASETLSLMAELALSGELQHLTAERVWLETEKALNEKNPEIY
                     FETLHKTGALSVLFPEIDA"
     PFAM_domain     7291..7551
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_466_0050"
                     /evalue="4.60E-08"
                     /label="ctg1_466"
                     /locus_tag="ctg1_466"
                     /protein_end="315"
                     /protein_start="228"
                     /score="33.4"
                     /tool="antismash"
                     /translation="FIHTMLVLKQAVNLTENNPILNKSAVRFAAICHDLGKALTPQNIL
                     PHHYGHEQAGIKPTRSLCKRLKVPSYFQELAELTCEFHTHIH"
ORIGIN
        1 ttagccctca aagccaagct gttggtggcg tttaatccat ttatctaccg ttggacggct
       61 aatattaaac tgctgacaca gttcagtttt agtatagcgt tggcttagcc acgcttttaa
      121 gaaaagtaca cgctgttgca tcgcatcggt ctctatccaa ggcatcatca atctccagtg
      181 gattaggtat tttgatgatg agtttacggg aaaaatgtaa acgatgtcct cgggttagaa
      241 tgtaaatgat gttatcaggt tgtgccccct ctttgagaaa gagggggtag aaaaattatc
      301 ttgttctaat cttgctataa gctaatgcta taacaaaaaa tgtggcttgc agaagaataa
      361 tacaagcacc tgttgaggca tcaaaatgat agctcaatat tacaccaatt aggcttgata
      421 taattgaact tataatagca atccataaca ttttatcaaa agatttgtga gcgtaagtgc
      481 ggtaattctt gacgcaatta acattaccac caccaaaata acgcctacca cttgcatcgt
      541 acttacaatg gttaaagcaa gcagcattaa caaaccatat agcggtcgaa tttctgaact
      601 tctctgacaa ttgttcccaa aaatcaacgg acaagttaat acctttggct tgcttgatat
      661 cacgtaagtc atgctacaac taggatgcct tgaatgtgta tatgccgaaa tcaatatcgc
      721 ttttcgcctg caaacgtgaa aagcagattt tcaacgaatt tacaggtaat aatcacgtct
      781 cccttgctaa gaagtatgct ttatcgttgc aatggatcta caaaatcgtc aaacgtgtgc
      841 agaaagaaga aattgccaaa cggcagttta atatgttcgc ccaatcctaa aaacaaaccc
      901 agtaactgta aaaaagtctc taggttttct ttttatctat gtgtaactcc gcttcatttc
      961 tcctttctca tttcttcccc acttccttca aattcttctc attgatgttg gattatgcgt
     1021 gagagttatg ttggatggct ttatctacaa acaaattttt atttattgtg attaaaatat
     1081 tgcgactttt aaataaaaaa ataatccgaa aaacataaac agatttcatc ggataatatt
     1141 gataatttta aataacaaag ccagattaaa atgtgaatat ttactaatct aaattagcaa
     1201 taattgtgaa atgtcaatta aaataagtaa gatgaaaata tgaatatttt catcttactc
     1261 agcattttca aaaattttat ctttgttcgg ggtaaattac ttcagatgta acccatttca
     1321 tccatacttg ctctaataat gggattattg acgtactatc ttcaaccatt gtattaagag
     1381 cagacaaaac attttctaat gaatttggtt gttcttgtag ataacttaac aaccagtaat
     1441 ctaactctga aaggatttgt tgctgaatcc taaaatcact atcacgccat ataataactt
     1501 gaattggcgt atcatcaaat tgtttaaagt cacttgataa aaaatcaact tcataacttt
     1561 ttaaataagc tgcgccagat aattgcatta cgctatgtct atcccactca aatttttcag
     1621 gcactttagc taaagaaact tctgcaagta attgtgtatt ttcaaaatcc atcaatgcca
     1681 atatatttgc atcaaatatc tctttttctt gacaaaacaa gagaaattct cctgcaatat
     1741 cttggaaata aggagaatgc gcattaccat tttgtacaaa attttcttta gcatttttcc
     1801 aatactctgg ctcaatatgc aatggtgctt caacaaaaca acgatcaata aaaccaaaag
     1861 cattattacg aactaaacgt gtatataccg ctaaacggtt tgcagcataa ccatttaaag
     1921 gatctgcatt acctaaccga atagcatttg ccagtgcttg ctgagtttct ttcagtaatg
     1981 acttaggctg cataagacat tacctctgtg tgagcgtatt tttgctgtaa ttgtgcaata
     2041 tgctcaactt cggcgtaaag ttctgcaaat ggtgggaagt tgaaatcacg ttccaataat
     2101 gttgggggaa tcgtaggtag tcgttgatag gcatattcga gtaaatccca tacagtgcct
     2161 tttacagctt caccgtgtgt atcaattaat aattcaggta aatggcgata tgctcctttt
     2221 actttattaa atgattcatc tgctgaattc tccacaactt gtgcagcaga atgttcttca
     2281 tcgtgccctg caatatgaat gtaattaaca cgtttaacat ccacttgatc taaaaagaca
     2341 taaggatcaa gcaatccgtg attaacacca ttaacataaa tattattcac atctaaatga
     2401 atgccacaat tagcctcttg tgcaatagca tttaaaaatt ccacttcatt cattgtacta
     2461 gttggagaat gcaaataata agaagtattt tctaatgaaa tttgcaatcc taagaaatct
     2521 tgcacatcac gtattcgttg cgcaacgtgt tttacagctt cttctgtaaa tggcataggt
     2581 aataaatcat ataaatgccc ttcacattca caataactta aatgttcaga aaagaaagat
     2641 gaattatatt gattcattag tgctttagta ttacggagta atttgcgatc aagtggtgct
     2701 tgcccaccta aagaaagtga aagaccgtgt actgctaatg gaaatctttc tgctgcttga
     2761 tcaaattgat aacgagccat tccacccatt ttactccaat tttctggtgc gacttcaata
     2821 aattgaatag cgttgtttgg gggaagttgt aaaaaatcct cagctaaatt ccgacgataa
     2881 cctaatccag caccttgtaa tttcataatt aactcctttt ttaataaaag ctggcataaa
     2941 ttcttacacc agcataatta ttattcttat ttagaaccgc atttaccttc gccacatttg
     3001 ccttcagcag ctttcggttt gctcgcacca catttaccct cgccacattt accttcagca
     3061 gatttagctt tatctgcacc gcatttgcct tcaccacact taccttctgc ggctttcgtt
     3121 ttgacacatt tatcgcctac acaaggtgtt gctgtattat cagtattgct tgactttgat
     3181 tcagcctgta ctgctgtcgc tactgccatc gttaatgcac ttgctaatgc tgttaatgtt
     3241 gctaattttt tcatttgaat aatctcctag agtttgaatt ttgaataaat aattagagaa
     3301 atttcaacca gcttttagtt ggataaacct tcttaataag cgtgtctaaa gagagtttcc
     3361 ccgctccctg tgtaattaag attaataaag tcaccacata aattaatggt aatttataac
     3421 cattatcaca tacgttataa cctgaatcgg cgtgaatgct ataccacgcg acagagatta
     3481 aaatcgttaa acttaatgca ctaaaacgtg ttagcactcc aaatatcagc aaaaatggga
     3541 aaattaattc tgatcccatt gcaacgtgcc aattaatatc agctggaata agattaaatg
     3601 gaaaaggaaa acgatcttgt atttcagcga accaattttg tccattccat ttttctaatc
     3661 ctgcttcaaa aaactcccac gcaagaaaaa agcgtaaaat caataaactt acgccactgc
     3721 cgataccttg catcttacaa tccttcattt ttttaccttt caaattttct cgcttttaaa
     3781 gcgaaaagtg tattgagtta cttatcttac tacactagga aatattaccc agttacttag
     3841 ttagtcgaag ataaaccttt tttcttacaa atttttttga aaaattttaa ctatcaacaa
     3901 aaatcaggta atatgcgcac gaatttttaa ccccttagtt tggagtaaat cacttatggc
     3961 aatgaataat attctcggat tatttgccca ttcgcctctc aagccgttac aaaaacactc
     4021 tgaaaaagtg accgaatgta gcgatctttt gattcctttt tttcaaacga ctttctcaaa
     4081 gaattgggaa caagcggaag aaaaacgctt agaaatttct caatgcgaac gtgaggcaga
     4141 tagtttaaaa cgcgaaattc ggttgaaatt gccacgtggt ttattcttac ctatcgatcg
     4201 tactgatctt ttagaattag tcacgcaaca agataaactt gccaattatg ccaaagatat
     4261 tgcaggccgt atgattggtc gtcaatttgg tattcctgaa gaaatgcagg aagaattctt
     4321 acattacgta aaacgtagtt tagatgccat tcatcaagcc caccgagtaa tcgaagaaat
     4381 ggataagcta ttagaaacgg gttttaaagg tcgtgaactc aaattagtca atgatatgat
     4441 tcaagaactt gatttaattg aagatgatac agaccaaatg cagatcaaat tgcgtaaaat
     4501 gctttacacc atcgaaagcc gttataatcc aattgatgta atgttcttat ataaaattat
     4561 tgaatgggtt ggcgttttgg ctgaccaagc acaacgagtc ggttcgcgca ttgaattaat
     4621 gctggcgcgt tcataatcaa caaaacatag gaaattaact atggaaatta ttagtcaata
     4681 tggttcttgg ttggtgtgga tcacagcagc ctttggcttt tttatggcgt tcggaattgg
     4741 agcaaatgat gtctcaaact caatgggtac atccgtagga tctggtactg taacagccaa
     4801 acaagcaatt attattgcgt taatttttga atctgcaggt gcatatttag ctggtggcga
     4861 agtaacacaa accataaaaa gtggcgtaat cgacccaatg caatttgttg atacacccga
     4921 tattttagcc ttaggtatgc tttcaacctt atttgcatca ggtgcttggt tatttattgc
     4981 aaccaaaatg ggttggccag tttctggtat acacactatt attggtgcaa ttattggatt
     5041 tgcctgtatt acgattggcc ctagttctgt agattggtca aatattggca gcatcgttgg
     5101 tagctggttt gtcacgcctg tcatctcggg tattttggct tatgcaatct ttgcaagtac
     5161 gcaaaaactt atttttgata ctgaacagcc attaaaaaat gcacaaaaat atggccctta
     5221 ttatatgggg ataaccatgt ttgtactttg tatcgtaacg atgaaaaaag gcttaaaaca
     5281 cgtaggctta aatctttcaa acagtgaaac tttaatcatt tcacttgcca tcagtcttat
     5341 cggaatgttt ttcttccatt tctatttcaa aagtaaaaca tttactcaat ctgcaagtaa
     5401 aggcaccttt gttgcagtag aaaaagtctt cagtatatta atgttattaa ccgcttgtgc
     5461 gatggcattt gcgcacggtt ctaatgacgt agccaatgca attggccctc tttctgcagt
     5521 ggtctctatt gtaaatgaag gcggtaaaat tgtttcaggt ggagccttaa cttggtggat
     5581 tttaccctta ggtgcattag gtattgctgt gggcttaatt actatgggac aaaaagtgat
     5641 ggcgactgtt ggatctggga tcaccgattt aacgccaagc cgtggctttg ccgctcaatt
     5701 tgctactgca atgactgttg tagttgcatc cggtacaggc ttgccgatct caacaacaca
     5761 aacacttgtt ggagctattt taggtatcgg ctttgcacgc ggtatcgctg cactgaattt
     5821 aacggttatc cgaaacatca ttagttcttg gattgtcaca ttaccagcag gtgcattttt
     5881 cgccattatt attttctatg tgctaagaac tatctttaat taattgatct caataaaaag
     5941 tgcggttaat tttaaccgca cttttgttgt gatgtttaag gggaaaaaat gaaaaagatc
     6001 tataaagcct taatctcatc tttactttta agtacatcaa taaatgttgc ttatgcggaa
     6061 acccaatatg ttactgaaaa tttaagtacg ttcttacgcc gtggtgctgg cgaacaattt
     6121 aaaattgcag gttcaattca agcaggcgaa gcggtgaatg tattagatcg ccaaggcaaa
     6181 tacacactca ttcgcgacaa taaaaatcgt gaagcttgga ttttaaattc agacttaagc
     6241 agtacgccaa gtagtaaaga agaaaatcca aaattaaaag cgcaagtcca agaattaacc
     6301 ttaaaactta gtcgtttaga tggcgattgg cagcaacgta ccgtcgaaat gcaacgtcga
     6361 accaaacaag ctgagcaaca aagtgcggat cttttagagc aaaattctca acttaaacgt
     6421 gaacttgaaa tgaccaaaaa taaaaatcgt gatttagaag cgatacttga tgcaggtaaa
     6481 cgagaaattg cgatccaatg gtttatttat ggcggttcag tattaggcgt aggcttactc
     6541 ttcggcttgc tcattcctta tgtgttacca aaacgtcgcc gtcgtgatgg ttgggcataa
     6601 tcacgaatga aaatttattt agttggtggg gctattcgtg atcaattatt ggggttacca
     6661 gtaaaagatc gtgattggat tgtggtaggc gcagaccccg ctacgctact ctctctcggt
     6721 tatcagcaag taggcaaaga ttttccagtt tttctcaatc ctaaaacaaa agaagaatat
     6781 gcgcttgccc gaacagaacg taaatctagc acaggttaca cgggctttat ttgtgatttc
     6841 tccccaacaa tcacattaga acaagattta attcgacgag atctcactat taacgcgatg
     6901 gctcaaagcg aagacggtga aattatcgat ccttatggcg gaaaacaaga tttagaaaat
     6961 cgaattttgc gccatatttc tcccgctttt tcagaagatc ctttacgtgt attgcgcgtg
     7021 gcacgctttg ctgcccgtta tcattccctc ggttttaaaa tcgcatcaga aacactatcc
     7081 ctaatggcag aacttgccct atcgggagaa ttacaacatc tcacggcgga acgcgtttgg
     7141 ctagaaacag aaaaagcctt aaacgaaaaa aatcctgaaa tttattttga aaccttacat
     7201 aaaacaggtg cattaagcgt tttatttcct gaaatcgatg ccctttatgg cgtaccaaat
     7261 ccagtaaaac atcatcccga agtggatagt tttattcata ccatgttggt attaaaacaa
     7321 gcggttaatt tgactgaaaa taaccctatc ctaaataaaa gtgcggttcg ttttgccgca
     7381 atttgtcatg atcttggcaa ggctcttaca cctcaaaata ttcttcctca tcattatggg
     7441 catgaacaag ctggcataaa accgactaga tcattgtgca aacgcttgaa agtcccaagt
     7501 tattttcaag aacttgcaga actgacttgt gaatttcaca cacatattca caaagccttt
     7561 gagcttcgag ctgaaaccgt cataacgctg tttaatcgtt ttgatgtgtg gagaaaatca
     7621 caacgctttc aagaatttct acaagtatgt ctagctgata ctcgaggtag aacaggtttt
     7681 gaaaataaag actatccaca aatagattac atcaatcaat tattgcatgc ggcaaatgaa
     7741 gtagatgtac agcaagttat tgctgatgga tttgagaaac aagcaatcaa aaatgaattg
     7801 acgaaacgaa gaatcttagc ggttaaacaa acaaaaacga attacccaac aaattaa
//
