GCF_004563945.1_ASM456394v1_genomic - 6 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_SPNK01000017 (original name was: NZ_SPNK01000017.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	terpene	8,086	28,985	carotenoid	Terpene	25%

NZ_SPNK01000001 (original name was: NZ_SPNK01000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	T3PKS	181,585	222,793	avilamycin A / avilamycin C	Saccharide:Oligosaccharide	5%

NZ_SPNK01000002 (original name was: NZ_SPNK01000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	siderophore	42,821	54,737
Region 15.2	NAPAA	90,062	124,105

NZ_SPNK01000004 (original name was: NZ_SPNK01000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 18.1	betalactone	189,847	216,680	microansamycin	Polyketide	7%

NZ_SPNK01000006 (original name was: NZ_SPNK01000006.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	RiPP-like	41,276	52,076

No secondary metabolite regions were found in these records:: NZ_SPNK01000010 (original name was: NZ_SPNK01000010.1); NZ_SPNK01000011 (original name was: NZ_SPNK01000011.1); NZ_SPNK01000012 (original name was: NZ_SPNK01000012.1); NZ_SPNK01000013 (original name was: NZ_SPNK01000013.1); NZ_SPNK01000014 (original name was: NZ_SPNK01000014.1); NZ_SPNK01000015 (original name was: NZ_SPNK01000015.1); NZ_SPNK01000016 (original name was: NZ_SPNK01000016.1); NZ_SPNK01000018 (original name was: NZ_SPNK01000018.1); NZ_SPNK01000019 (original name was: NZ_SPNK01000019.1); NZ_SPNK01000020 (original name was: NZ_SPNK01000020.1); NZ_SPNK01000021 (original name was: NZ_SPNK01000021.1); NZ_SPNK01000022 (original name was: NZ_SPNK01000022.1); NZ_SPNK01000023 (original name was: NZ_SPNK01000023.1); NZ_SPNK01000003 (original name was: NZ_SPNK01000003.1); NZ_SPNK01000005 (original name was: NZ_SPNK01000005.1); NZ_SPNK01000024 (original name was: NZ_SPNK01000024.1); NZ_SPNK01000007 (original name was: NZ_SPNK01000007.1); NZ_SPNK01000008 (original name was: NZ_SPNK01000008.1); NZ_SPNK01000009 (original name was: NZ_SPNK01000009.1)

Compact view

c00008_NZ_SPNK.. - Region 1 - terpene

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Location: 8,086 - 28,985 nt. (total: 20,900 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.34	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000644.1	0.24	Terpene	carotenoid	Dietzia sp. CQ4
BGC0001514.1	0.21	Other	aristeromycin	Streptomyces citricolor
BGC0001227.1	0.21	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000648.1	0.21	Terpene	carotenoid	Myxococcus xanthus
BGC0000513.1	0.20	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000637.1	0.20	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000641.1	0.18	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000642.1	0.18	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000639.1	0.18	Terpene	carotenoid	Enterobacteriaceae bacterium DC260

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.67	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000644.1	0.58	Terpene	carotenoid	Dietzia sp. CQ4
BGC0001514.1	0.54	Other	aristeromycin	Streptomyces citricolor
BGC0001227.1	0.54	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000648.1	0.53	Terpene	carotenoid	Myxococcus xanthus
BGC0000513.1	0.53	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000637.1	0.53	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000641.1	0.49	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000642.1	0.49	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000639.1	0.49	Terpene	carotenoid	Enterobacteriaceae bacterium DC260

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c00011_NZ_SPNK.. - Region 1 - T3PKS

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Location: 181,585 - 222,793 nt. (total: 41,209 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001962.1	0.36	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001938.1	0.35	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001831.1	0.25	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001947.1	0.16	Saccharide	K53 capsular polysaccharide	Acinetobacter baumannii
BGC0001191.1	0.16	Other	A-102395	Amycolatopsis sp. SANK 60206
BGC0001964.1	0.13	Polyketide	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0000026.1	0.09	Saccharide	avilamycin A, avilamycin C	Streptomyces viridochromogenes Tue57
BGC0001669.1	0.09	RiPP	microvionin	Microbacterium arborescens
BGC0001566.1	0.09	Polyketide	cylindrocyclophane	Cylindrospermum licheniforme UTEX B 2014
BGC0001064.1	0.08	Polyketide	cylindrocyclophane D, cylindrocyclophane E, cylindrocyclophane F	Cylindrospermum licheniforme UTEX B 2014

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001962.1	0.69	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001938.1	0.68	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001831.1	0.58	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001947.1	0.47	Saccharide	K53 capsular polysaccharide	Acinetobacter baumannii
BGC0001191.1	0.46	Other	A-102395	Amycolatopsis sp. SANK 60206
BGC0001964.1	0.42	Polyketide	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0000026.1	0.34	Saccharide	avilamycin A, avilamycin C	Streptomyces viridochromogenes Tue57
BGC0001669.1	0.33	RiPP	microvionin	Microbacterium arborescens
BGC0001566.1	0.33	Polyketide	cylindrocyclophane	Cylindrospermum licheniforme UTEX B 2014
BGC0001064.1	0.32	Polyketide	cylindrocyclophane D, cylindrocyclophane E, cylindrocyclophane F	Cylindrospermum licheniforme UTEX B 2014

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c00015_NZ_SPNK.. - Region 1 - siderophore

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Location: 42,821 - 54,737 nt. (total: 11,917 nt) Show pHMM detection rules used

siderophore: IucA_IucC

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.1	0.39	Other	desferrioxamine E	Pantoea agglomerans
BGC0001478.1	0.32	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.29	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.28	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.28	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001531.1	0.20	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000295.1	0.17	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0000244.1	0.16	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000939.1	0.16	Other	aerobactin	Grimontia hollisae
BGC0001551.1	0.16	RiPP	citrulassin E	Streptomyces glaucescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.1	0.71	Other	desferrioxamine E	Pantoea agglomerans
BGC0001478.1	0.65	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.63	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.62	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.61	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001531.1	0.52	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000295.1	0.49	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0000244.1	0.47	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000939.1	0.46	Other	aerobactin	Grimontia hollisae
BGC0001551.1	0.46	RiPP	citrulassin E	Streptomyces glaucescens

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c00015_NZ_SPNK.. - Region 2 - NAPAA

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Location: 90,062 - 124,105 nt. (total: 34,044 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

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NRPS/PKS modules

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Detailed domain annotation

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.20	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001479.1	0.18	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001758.1	0.18	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001168.1	0.18	NRP	livipeptin	Streptomyces lividans 1326
BGC0001844.1	0.18	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.18	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001641.1	0.18	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000375.1	0.18	NRP	indigoidine	Streptomyces chromofuscus
BGC0001900.1	0.18	NRP	fragin	Burkholderia cenocepacia H111
BGC0001128.1	0.18	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.53	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001479.1	0.50	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001758.1	0.49	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001168.1	0.49	NRP	livipeptin	Streptomyces lividans 1326
BGC0001844.1	0.49	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.49	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001641.1	0.49	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000375.1	0.49	NRP	indigoidine	Streptomyces chromofuscus
BGC0001900.1	0.49	NRP	fragin	Burkholderia cenocepacia H111
BGC0001128.1	0.49	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters

No matches found.

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 90061 - 124105:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg15_89

Search NORINE for peptide: strict or relaxed

AMP-binding (16..388): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIGtViK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

c00018_NZ_SPNK.. - Region 1 - betalactone

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Location: 189,847 - 216,680 nt. (total: 26,834 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

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KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000649.1	0.23	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000234.1	0.21	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001444.1	0.20	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001935.1	0.19	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.19	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001538.1	0.18	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001910.1	0.17	Terpene	cyslabdan	Streptomyces cyslabdanicus
BGC0000698.1	0.17	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0000664.1	0.17	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000286.1	0.17	Polyketide	viguiepinol	Streptomyces sp. KO-3988

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000649.1	0.56	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000234.1	0.53	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001444.1	0.53	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001935.1	0.51	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.51	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001538.1	0.50	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001910.1	0.49	Terpene	cyslabdan	Streptomyces cyslabdanicus
BGC0000698.1	0.49	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0000664.1	0.49	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000286.1	0.49	Polyketide	viguiepinol	Streptomyces sp. KO-3988

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c00020_NZ_SPNK.. - Region 1 - RiPP-like

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Location: 41,276 - 52,076 nt. (total: 10,801 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001882.1	0.18	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0001484.1	0.14	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0000265.1	0.13	Polyketide	rhodomycin	Streptomyces purpurascens
BGC0000666.1	0.13	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0000665.1	0.13	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0001223.1	0.07	Other	hydroxysporine	uncultured bacterium
BGC0000275.1	0.06	Polyketide	tetracenomycin C	Streptomyces glaucescens
BGC0001489.1	0.06	Polyketide	6-hydroxymellein	Cladonia uncialis subsp. uncialis
BGC0001335.1	0.05	Alkaloid	borregomycin A, borregomycin B, borregomycin C, borregomycin D	uncultured bacterium
BGC0001848.1	0.05	Other	diazaquinomycin H, diazaquinomycin J	Micromonospora sp. B006

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001882.1	0.50	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0001484.1	0.43	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0000265.1	0.42	Polyketide	rhodomycin	Streptomyces purpurascens
BGC0000666.1	0.42	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0000665.1	0.41	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0001223.1	0.29	Other	hydroxysporine	uncultured bacterium
BGC0000275.1	0.25	Polyketide	tetracenomycin C	Streptomyces glaucescens
BGC0001489.1	0.24	Polyketide	6-hydroxymellein	Cladonia uncialis subsp. uncialis
BGC0001335.1	0.23	Alkaloid	borregomycin A, borregomycin B, borregomycin C, borregomycin D	uncultured bacterium
BGC0001848.1	0.23	Other	diazaquinomycin H, diazaquinomycin J	Micromonospora sp. B006

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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