LOCUS       c00018_NZ_SPNK..       26834 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SPNK01000004.1 Kocuria rhizophila strain 4R-31
            NODE_4_length_245819_cov_234.648609, whole genome shotgun sequence.
ACCESSION   NZ_SPNK01000004
VERSION     NZ_SPNK01000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:54:47
            Original ID  :: NZ_SPNK01000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 189846
            Orig. end    :: 216680
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..26834
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[199846:206680]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16834
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..26834
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..26834
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             1336..2448
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 252.3; E-value:
                     8.7e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_165"
                     /transl_table=11
                     /translation="MTSTDDPAATAAAQDAQFSARLDTAIREFFAAERERVTAISPDAT
                     RLVAAIADLTDGGKRLRARLCHWGWCAAGGEAGSDVVVAAAASLELFQTAALIHDDVLD
                     RSDTRRGRPSVHRVFEAVHREAGWAADPEHFGVGAAVLTGDMSLSFAEQLFAEAAAGVA
                     PAAGAAARHIFSSMRTEVMAGQYLDIHAEVAPPSHDAAVQLERAMTVLRYKSAKYSVEH
                     AVAIGAALAGADDEFLAACAAFTLPLGEAFQLRDDVLGVFGDPETTGKPAGDDIREGKR
                     TALIALCSAGCSPAQRQWLESVLGSERLTEEDVARVRDLMRSSGAHERSEQLIADLVAS
                     SDAALAVLPTGEVPRAGLRALADAAVRRTR"
     PFAM_domain     1483..2295
                     /aSDomain="polyprenyl_synt"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00348.19"
                     /description="Polyprenyl synthetase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_165_0001"
                     /evalue="3.30E-54"
                     /label="ctg18_165"
                     /locus_tag="ctg18_165"
                     /protein_end="320"
                     /protein_start="49"
                     /score="183.7"
                     /tool="antismash"
                     /translation="AIADLTDGGKRLRARLCHWGWCAAGGEAGSDVVVAAAASLELFQT
                     AALIHDDVLDRSDTRRGRPSVHRVFEAVHREAGWAADPEHFGVGAAVLTGDMSLSFAEQ
                     LFAEAAAGVAPAAGAAARHIFSSMRTEVMAGQYLDIHAEVAPPSHDAAVQLERAMTVLR
                     YKSAKYSVEHAVAIGAALAGADDEFLAACAAFTLPLGEAFQLRDDVLGVFGDPETTGKP
                     AGDDIREGKRTALIALCSAGCSPAQRQWLESVLGSERLTEEDVARVRDL"
     CDS             complement(2543..2929)
                     /locus_tag="ctg18_166"
                     /transl_table=11
                     /translation="VNYATDLTPQEFAELDALVGEWTHLPDIAEAMDIQITRVHRLMDD
                     GSLLEVRRPEDRVRVVPAAFMDGSHPVDSLKGTVAVLRDAAYTDAQAIRWLFTEDESLP
                     GRPIDALRRGQKTEVRRRAQALGW"
     PFAM_domain     complement(2549..2716)
                     /aSDomain="Rv2175c_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18367.3"
                     /description="Rv2175c C-terminal domain of unknown
                     function"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_166_0002"
                     /evalue="1.00E-27"
                     /label="ctg18_166"
                     /locus_tag="ctg18_166"
                     /protein_end="127"
                     /protein_start="71"
                     /score="96.1"
                     /tool="antismash"
                     /translation="VDSLKGTVAVLRDAAYTDAQAIRWLFTEDESLPGRPIDALRRGQK
                     TEVRRRAQALG"
     CDS             3072..4196
                     /locus_tag="ctg18_167"
                     /transl_table=11
                     /translation="MPVEPPHDRHTPRGQWSRRAAHGSVAALTALTALGTMGAAQAAPA
                     TPQTVQVAQQHAGQVTVAPGDSVWSLATRHGVSVSELMAANDIPAHGMIRPGQRLRIPE
                     TSNPADGEAAPARGKNAPKPSPAGGSSTPAPARTHHSVAAGDTLWDLALRYEVSVGDLL
                     RANSLSPNDVLRPGRTLVIPGAAPEHRADAAVSSPAPERSGTAAPDEEPAVGDSFAGRQ
                     YPREVVDSANAHHEQLRSRAVPPPAQIRQMVEATARDMGVDPALALAHASQESGFRHDV
                     VSPADAVGTMQVVPAAGDWASAMVGRDLDLLDPQDNITAGMAIIRALQDRAPDKATGIG
                     AYYQGLHGVTTYGMYSDTKAYVKAVSAQERKFAQ"
     PFAM_domain     3252..3380
                     /aSDomain="LysM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01476.22"
                     /description="LysM domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_167_0003"
                     /evalue="1.30E-13"
                     /label="ctg18_167"
                     /locus_tag="ctg18_167"
                     /protein_end="103"
                     /protein_start="60"
                     /score="50.9"
                     /tool="antismash"
                     /translation="TVAPGDSVWSLATRHGVSVSELMAANDIPAHGMIRPGQRLRIP"
     PFAM_domain     3489..3620
                     /aSDomain="LysM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01476.22"
                     /description="LysM domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_167_0004"
                     /evalue="1.10E-12"
                     /label="ctg18_167"
                     /locus_tag="ctg18_167"
                     /protein_end="183"
                     /protein_start="139"
                     /score="47.8"
                     /tool="antismash"
                     /translation="HSVAAGDTLWDLALRYEVSVGDLLRANSLSPNDVLRPGRTLVIP"
     PFAM_domain     3828..4148
                     /aSDomain="SLT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01464.22"
                     /description="Transglycosylase SLT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_167_0005"
                     /evalue="6.30E-14"
                     /label="ctg18_167"
                     /locus_tag="ctg18_167"
                     /protein_end="359"
                     /protein_start="252"
                     /score="51.7"
                     /tool="antismash"
                     /translation="VEATARDMGVDPALALAHASQESGFRHDVVSPADAVGTMQVVPAA
                     GDWASAMVGRDLDLLDPQDNITAGMAIIRALQDRAPDKATGIGAYYQGLHGVTTYGMYS
                     DTK"
     CDS             4201..6183
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 248.7;
                     E-value: 1.2e-75)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg18_168"
                     /sec_met_domain="Pkinase (E-value: 8.4e-46, bitscore:
                     150.1, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDHRVGALLENRYRVLRRIAHGGTAAVYEGLDERLDRPVALKIM
                     HPHFADDPRFVTRAEREAKAAARLHDPHVVAVLDQGRTDDGVLYLVLEFVDGPTLREVV
                     AREAPMDPHRALELLVPVLRGLARAHRTGLVHRDVKPENVLLTADGQVKVADFGLTRAV
                     DDHTTSTTVLGTVGYAAPELVGDGPVDQRSDVYAVGIMAYEMLTGSRPYTGTALQVATA
                     HVSRDVPAPSGIAAGVPPALDEFVLRATSRDASRRPADAAELLDLALAVRRSLPAPADP
                     LLLGEAATEVLAGGPHSPTGHPEEAPTEAVGAGTADGSGEEATEAMGPGGQDLPTEAIG
                     TPTQEAPTEALGTPWHEAPTEALGTGPHEAPTEALGTGPHGAPTEVVGANAGVPPGGHG
                     TPILPAYEEDATGTVALTQVGSTAHRSPHEPRVRLNPPAQPLHVALVLVVFALLLTVAA
                     FLGWWLGSAPGTATATVPPVAGQDTAAAERTLNAAGISNVGVSTTPSCEAPEGTVISTD
                     PAAPATVRGIEQVNLLVSSGPAQVDVPALTGMSADDAGAAVSAAGLGLGGVTREYSTRP
                     AGTVLSQSPEAGSRVDEGTQMSLTVATDSPQGPVPNVVGKDAETARTTLEEQGYTVQID
                     SPVGSHLNRVVRQREDGDTVVLTVL"
     PFAM_domain     4240..4857
                     /aSDomain="Pkinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00069.27"
                     /description="Protein kinase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_168_0006"
                     /evalue="1.00E-44"
                     /label="ctg18_168"
                     /locus_tag="ctg18_168"
                     /protein_end="219"
                     /protein_start="13"
                     /score="153.0"
                     /tool="antismash"
                     /translation="YRVLRRIAHGGTAAVYEGLDERLDRPVALKIMHPHFADDPRFVTR
                     AEREAKAAARLHDPHVVAVLDQGRTDDGVLYLVLEFVDGPTLREVVAREAPMDPHRALE
                     LLVPVLRGLARAHRTGLVHRDVKPENVLLTADGQVKVADFGLTRAVDDHTTSTTVLGTV
                     GYAAPELVGDGPVDQRSDVYAVGIMAYEMLTGSRPYTGTALQV"
     PFAM_domain     5620..5805
                     /aSDomain="PASTA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03793.21"
                     /description="PASTA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_168_0007"
                     /evalue="6.10E-10"
                     /label="ctg18_168"
                     /locus_tag="ctg18_168"
                     /protein_end="535"
                     /protein_start="473"
                     /score="38.9"
                     /tool="antismash"
                     /translation="TVPPVAGQDTAAAERTLNAAGISNVGVSTTPSCEAPEGTVISTDP
                     AAPATVRGIEQVNLLVS"
     PFAM_domain     5821..6006
                     /aSDomain="PASTA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03793.21"
                     /description="PASTA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_168_0008"
                     /evalue="3.00E-14"
                     /label="ctg18_168"
                     /locus_tag="ctg18_168"
                     /protein_end="602"
                     /protein_start="540"
                     /score="52.7"
                     /tool="antismash"
                     /translation="VDVPALTGMSADDAGAAVSAAGLGLGGVTREYSTRPAGTVLSQSP
                     EAGSRVDEGTQMSLTVA"
     CDS             complement(6272..7666)
                     /locus_tag="ctg18_169"
                     /transl_table=11
                     /translation="MSSETLPEQLRSVMTPSPSAADYPGLDEWRGRSIGQHPQWAEHPD
                     FAATIQELGAVPPLVFAGEVDTLRERLAQVANGEAFFLQGGDCAETFAGATADKISGRV
                     RTLLQMAVVLTYGASMPVVKMGRMAGQFSKPRSSNEETRDGVTLPSFRGEMVNGFDFTE
                     ESRVHDPRRMLRGYHTSASTLNLIRAFTQGGFADLRRVHAWNMGFAANPAYARYESMAR
                     EIDHAVKFMAACGSDFDALKTTEFFAGHEALLLDYERALTRIDSRTHLPYGTSGHFLWI
                     GERTRDLDGAHVDLLSRLRNPIGVKLGPGTSGDDALRLIDALDPDREPGRLTFITRMGA
                     KNIREKLPPVIKAVEDSGAKPVWVTDPMHGNTVSLASGYKTRNFEDVVDEVRGFFEVHR
                     ELGTFPGGIHVEMTGDDVAECLGGSDPVAESSFAERYETLCDPRLNHKQSLEIAFLVAE
                     YLSAQH"
     aSDomain        complement(6281..7588)
                     /aSDomain="TIGR01358"
                     /aSTool="tigrfam"
                     /description="DAHP_synth_II: 3-deoxy-7-phosphoheptulonate
                     synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg18_169_0001"
                     /evalue="1.30E-201"
                     /identifier="TIGR01358"
                     /label="ctg18_169"
                     /locus_tag="ctg18_169"
                     /protein_end="462"
                     /protein_start="26"
                     /score="667.8"
                     /tool="antismash"
                     /translation="DEWRGRSIGQHPQWAEHPDFAATIQELGAVPPLVFAGEVDTLRER
                     LAQVANGEAFFLQGGDCAETFAGATADKISGRVRTLLQMAVVLTYGASMPVVKMGRMAG
                     QFSKPRSSNEETRDGVTLPSFRGEMVNGFDFTEESRVHDPRRMLRGYHTSASTLNLIRA
                     FTQGGFADLRRVHAWNMGFAANPAYARYESMAREIDHAVKFMAACGSDFDALKTTEFFA
                     GHEALLLDYERALTRIDSRTHLPYGTSGHFLWIGERTRDLDGAHVDLLSRLRNPIGVKL
                     GPGTSGDDALRLIDALDPDREPGRLTFITRMGAKNIREKLPPVIKAVEDSGAKPVWVTD
                     PMHGNTVSLASGYKTRNFEDVVDEVRGFFEVHRELGTFPGGIHVEMTGDDVAECLGGSD
                     PVAESSFAERYETLCDPRLNHKQSLEIAFLVAEYLSA"
     PFAM_domain     complement(6296..7588)
                     /aSDomain="DAHP_synth_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01474.18"
                     /description="Class-II DAHP synthetase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_169_0009"
                     /evalue="4.10E-189"
                     /label="ctg18_169"
                     /locus_tag="ctg18_169"
                     /protein_end="457"
                     /protein_start="26"
                     /score="628.7"
                     /tool="antismash"
                     /translation="DEWRGRSIGQHPQWAEHPDFAATIQELGAVPPLVFAGEVDTLRER
                     LAQVANGEAFFLQGGDCAETFAGATADKISGRVRTLLQMAVVLTYGASMPVVKMGRMAG
                     QFSKPRSSNEETRDGVTLPSFRGEMVNGFDFTEESRVHDPRRMLRGYHTSASTLNLIRA
                     FTQGGFADLRRVHAWNMGFAANPAYARYESMAREIDHAVKFMAACGSDFDALKTTEFFA
                     GHEALLLDYERALTRIDSRTHLPYGTSGHFLWIGERTRDLDGAHVDLLSRLRNPIGVKL
                     GPGTSGDDALRLIDALDPDREPGRLTFITRMGAKNIREKLPPVIKAVEDSGAKPVWVTD
                     PMHGNTVSLASGYKTRNFEDVVDEVRGFFEVHRELGTFPGGIHVEMTGDDVAECLGGSD
                     PVAESSFAERYETLCDPRLNHKQSLEIAFLVA"
     CDS             complement(7676..8542)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 194.7; E-value: 2.3e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_170"
                     /transl_table=11
                     /translation="MVYMFLRNYVVAPVVNRVCRPTVIGLEHVPSHGPAILASNHLSVP
                     DTIFMPVAVPRQVFFLAKSEYFNTPGLKGRLTAAFFKAINQIPMDRRGGQASAKSLSAG
                     GQALAEGKLLGIYPEGTRSPDGRLYRGKVGVARLALESGAPVIPVAMIGTDKMQPLGSR
                     FPDPRRARITTIFGEPMDFSHLRGQQVDHATLRRVTDEIMAAIQRLSGQEVADVYATEH
                     KRRMADGKTSALLAQAKEVAQATRDKGRSVTDAVSQQAGHLNDTLHRRPHGGTDSGADD
                     GTPGPTA"
     PFAM_domain     complement(8090..8482)
                     /aSDomain="Acyltransferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01553.23"
                     /description="Acyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_170_0010"
                     /evalue="7.90E-25"
                     /label="ctg18_170"
                     /locus_tag="ctg18_170"
                     /protein_end="151"
                     /protein_start="20"
                     /score="87.1"
                     /tool="antismash"
                     /translation="PTVIGLEHVPSHGPAILASNHLSVPDTIFMPVAVPRQVFFLAKSE
                     YFNTPGLKGRLTAAFFKAINQIPMDRRGGQASAKSLSAGGQALAEGKLLGIYPEGTRSP
                     DGRLYRGKVGVARLALESGAPVIPVAM"
     CDS             8674..9462
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_171"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-11, bitscore:
                     39.3, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDLQRHDSLNLPGTSSVGVLVLHGFSSTTASVADWARAIHTAT
                     DAAGAAPGVRVPLLPGHGTHWQDLAAQPWQAWRDAVDEHYWQLRQRHEHVVVCGLSMGG
                     ALALHTAARREVAGVLLVNPALSLVNRAARFSRVLASAVPSYAGIGSDIRKESVLESAY
                     DRTPLAAVAQLNVLMHRTVQMLPAVTAPAIVFRSEVDHVVSGASADLVAQRTRGPVRVV
                     PLPDSYHVATLDHDAPLVEQTSRDAVQRVCRGLPLLPETA"
     PFAM_domain     8734..9393
                     /aSDomain="Abhydrolase_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12697.9"
                     /description="Alpha/beta hydrolase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_171_0011"
                     /evalue="3.70E-09"
                     /label="ctg18_171"
                     /locus_tag="ctg18_171"
                     /protein_end="240"
                     /protein_start="20"
                     /score="37.6"
                     /tool="antismash"
                     /translation="VLVLHGFSSTTASVADWARAIHTATDAAGAAPGVRVPLLPGHGTH
                     WQDLAAQPWQAWRDAVDEHYWQLRQRHEHVVVCGLSMGGALALHTAARREVAGVLLVNP
                     ALSLVNRAARFSRVLASAVPSYAGIGSDIRKESVLESAYDRTPLAAVAQLNVLMHRTVQ
                     MLPAVTAPAIVFRSEVDHVVSGASADLVAQRTRGPVRVVPLPDSYHVATLDHDAPLV"
     CDS             9459..9872
                     /locus_tag="ctg18_172"
                     /transl_table=11
                     /translation="VSSRDGSEDPFESIIRSNTWDDVPGDDEDMEPWAEDLEWVPREQP
                     PEDVPEELDEVDEDAVYDPDPGPVTGGVSPAMLRALSVLLAVLVIMLGLAVLPGPLPGV
                     VWGAGLAGTVAGLFLVFGALPEDSPEDDDGAVL"
     CDS             10001..11809
                     /NRPS_PKS="Domain: AMP-binding (21-470). E-value: 3.6e-94.
                     Score: 307.4. Matches aSDomain:
                     nrpspksdomains_ctg18_173_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     266.1; E-value: 8.1e-81)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_173"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-88, bitscore:
                     290.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVSAPAIVDPLPYPGIAHILEERARTQPDLVLYTILAPGRERD
                     VTAREFRAEVVALAHGMAAQGIRPGDRVGLLSRTRYEWTLVDFALWWLGAVPVPVYDTS
                     SPDQIAWILSDSRATAVFVETDELAGRVREAHRITPFPAEQRIRVFDTDDAQISLDAVV
                     RAGAGREDLQTPYDGVSLDDAATLIYTSGTTGPPKGCELTHRNFVACSQNTIPVAGELM
                     HEGARTLLFLPLAHVFARFVEVTSLDAGIALAHTPDVSQLMDDLARFKPTFILAVPRVF
                     EKILVGARFKAQAGSPVKKLIFERAVATAAAWSKASQQGRVSPWLAARHRLYDKLVYST
                     LREAMGGEVRYAVSGGAALGEHLAHFFNGIGVYVVEGYGLTETTAPISANVPSINRLGT
                     VGHPMPGNEVAIAEDGEILVRGVNVFERYNGLPEKTAEAFHDGWFATGDLGHLDDEGLL
                     TVTGRKKEIIVTASGKNVIPTMLEDPIRASATVGQIMVVGENRPFVAALITLDPETLAN
                     VLPTLGLDPGLSIAEASREKAVIEHVQRIVDHANTKVSRAEGIKAFRILDRDLTVEDGY
                     LTPSLKLKRAVVAEDFADVIDGIYAR"
     aSDomain        10064..11410
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_173_AMP-binding.1"
                     /evalue="3.60E-94"
                     /label="ctg18_173_AMP-binding.1"
                     /locus_tag="ctg18_173"
                     /protein_end="470"
                     /protein_start="21"
                     /score="307.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="LEERARTQPDLVLYTILAPGRERDVTAREFRAEVVALAHGMAAQG
                     IRPGDRVGLLSRTRYEWTLVDFALWWLGAVPVPVYDTSSPDQIAWILSDSRATAVFVET
                     DELAGRVREAHRITPFPAEQRIRVFDTDDAQISLDAVVRAGAGREDLQTPYDGVSLDDA
                     ATLIYTSGTTGPPKGCELTHRNFVACSQNTIPVAGELMHEGARTLLFLPLAHVFARFVE
                     VTSLDAGIALAHTPDVSQLMDDLARFKPTFILAVPRVFEKILVGARFKAQAGSPVKKLI
                     FERAVATAAAWSKASQQGRVSPWLAARHRLYDKLVYSTLREAMGGEVRYAVSGGAALGE
                     HLAHFFNGIGVYVVEGYGLTETTAPISANVPSINRLGTVGHPMPGNEVAIAEDGEILVR
                     GVNVFERYNGLPEKTAEAFHDGWFATGDLGHLDDEGLLTVTGRKKEIIVT"
     PFAM_domain     10064..11410
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_173_0012"
                     /evalue="8.90E-93"
                     /label="ctg18_173"
                     /locus_tag="ctg18_173"
                     /protein_end="470"
                     /protein_start="21"
                     /score="311.3"
                     /tool="antismash"
                     /translation="LEERARTQPDLVLYTILAPGRERDVTAREFRAEVVALAHGMAAQG
                     IRPGDRVGLLSRTRYEWTLVDFALWWLGAVPVPVYDTSSPDQIAWILSDSRATAVFVET
                     DELAGRVREAHRITPFPAEQRIRVFDTDDAQISLDAVVRAGAGREDLQTPYDGVSLDDA
                     ATLIYTSGTTGPPKGCELTHRNFVACSQNTIPVAGELMHEGARTLLFLPLAHVFARFVE
                     VTSLDAGIALAHTPDVSQLMDDLARFKPTFILAVPRVFEKILVGARFKAQAGSPVKKLI
                     FERAVATAAAWSKASQQGRVSPWLAARHRLYDKLVYSTLREAMGGEVRYAVSGGAALGE
                     HLAHFFNGIGVYVVEGYGLTETTAPISANVPSINRLGTVGHPMPGNEVAIAEDGEILVR
                     GVNVFERYNGLPEKTAEAFHDGWFATGDLGHLDDEGLLTVTGRKKEIIVT"
     CDS_motif       10553..10612
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_173_0001"
                     /evalue="4.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg18_173"
                     /protein_end="204"
                     /protein_start="184"
                     /score="22.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGPPKGCELTH"
     CDS_motif       11243..11317
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_173_0002"
                     /evalue="2.20E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg18_173"
                     /protein_end="439"
                     /protein_start="414"
                     /score="13.7"
                     /tool="antismash"
                     /translation="GEILVRGVNVFERYNGLPEKTAEAF"
     CDS             complement(11870..13303)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175:pyridine nucleotide-disulfide oxidoreductase
                     (Score: 393.6; E-value: 1.6e-119)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_174"
                     /transl_table=11
                     /translation="MGPMRSFDLIIVGSGSGNSLLTDEYRDLDVAIVEPGRFGGTCLNV
                     GCIPTKMYVYPATVADQARDAGRLGLDATVDGVDWPGMRDRIFGRIDAISEGGLDYRRS
                     LENVTVIQEYVHFVEPRVLETDSGERITAPRIVLANGSRVHVPDVPGTDLPGVHTSDTV
                     MRIPELPRDVVVVGGGYIAAEFCHVFQGLGASVTQLNRSQRLLRAHDDTIAERFTREAA
                     AHWDLQLGWSLTGILTSEDGRLKVSADASDGSGKQWERTADVVLLATGRIPNADTLNPG
                     AAHLDVTERGLLAVDEQQRVLSGGQPVEGLWALGDVSSPHQLKHVANAEARVVSHNVVH
                     PDDQRSTDHRFVPAAVFTEPQIASVGMTERAARAWAERTGHEITVKVQDFGDVAYGWAM
                     EDHVGLCKLIADSGTGELLGAHLIGREASNLIQPLVQGMAFGLRVHEMARGQYWIHPAL
                     AEVVENALLGLDVPGQRAD"
     PFAM_domain     complement(11909..12250)
                     /aSDomain="Pyr_redox_dim"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02852.24"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase, dimerisation domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_174_0014"
                     /evalue="6.80E-23"
                     /label="ctg18_174"
                     /locus_tag="ctg18_174"
                     /protein_end="465"
                     /protein_start="351"
                     /score="81.1"
                     /tool="antismash"
                     /translation="VPAAVFTEPQIASVGMTERAARAWAERTGHEITVKVQDFGDVAYG
                     WAMEDHVGLCKLIADSGTGELLGAHLIGREASNLIQPLVQGMAFGLRVHEMARGQYWIH
                     PALAEVVENA"
     PFAM_domain     complement(12314..13282)
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07992.16"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_174_0013"
                     /evalue="5.30E-38"
                     /label="ctg18_174"
                     /locus_tag="ctg18_174"
                     /protein_end="330"
                     /protein_start="7"
                     /score="131.0"
                     /tool="antismash"
                     /translation="DLIIVGSGSGNSLLTDEYRDLDVAIVEPGRFGGTCLNVGCIPTKM
                     YVYPATVADQARDAGRLGLDATVDGVDWPGMRDRIFGRIDAISEGGLDYRRSLENVTVI
                     QEYVHFVEPRVLETDSGERITAPRIVLANGSRVHVPDVPGTDLPGVHTSDTVMRIPELP
                     RDVVVVGGGYIAAEFCHVFQGLGASVTQLNRSQRLLRAHDDTIAERFTREAAAHWDLQL
                     GWSLTGILTSEDGRLKVSADASDGSGKQWERTADVVLLATGRIPNADTLNPGAAHLDVT
                     ERGLLAVDEQQRVLSGGQPVEGLWALGDVSSPHQLKHVANAE"
     CDS             complement(13385..16834)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     137.1; E-value: 1.3e-41)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_175"
                     /sec_met_domain="HMGL-like (E-value: 8.8e-30, bitscore:
                     97.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.1e-09, bitscore:
                     31.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSKILVANRGEIAIRAFRAAYELGAGTVAVFPHEDRNSIHRQKA
                     DEAYNIGEEGHPVRAYLDVAEIVRVAKESGADAIYPGYGFLSENPELARAAAAEGITFV
                     GPRAEILELAGNKVEALRAARRAGIPTLDSSEPSSDKDALIAAAEKIGYPVFVKAVAGG
                     GGRGMRRVESPEQLPGALDAAMREADTAFGDPTVFIEQAVLRPRHIEVQILADNEGNIV
                     HLFERDCSLQRRHQKVIEIAPAPQLEPEIRDALHRDAVKFAKELGYVNAGTVEFLVDTA
                     GERAGQHVFIEMNPRIQVEHTVTEEITDVDLVQSQLRIAAGETLEDLGISQDGLRVRGA
                     ALQCRITTEDPANDFRPDVGKVSAYRSAGGAGVRLDGGTLYAGAEISPHFDSMLVKLTC
                     RGRDYETAVLRARRALAEFRIRGIATNIQFLQSVLHNPDFLVGDVATDFIENHPDLLKG
                     KGSADRGTRALNYLAEITVNKPNGERVDGIDPRDKLPHYPGDKRDEPYRSPFDGPSKHE
                     VPSGWRQVLQEKGPEGFARALREYEPLAVTSTTFRDAHQSLLATRVRTRDLLAAAPAYA
                     HLLPGLLSVEAWGGATYDVALRFLGEDPWERLRLLREAMPNIPIQMLLRGRNTVGYTPY
                     PVEVTNAFVAEAAETGVDIFRIFDALNDVEQMRPAIEAVRATGTAVAEVALCYTGNMLD
                     PDETVYTLDYYLDLAQQCVDAGAHVLAIKDMAGLLRPEAARRLVTALRERFDLPLHLHT
                     HDTAGGQLATLLAASEAGVDAVDAAAASMAGTTSQVSGSALVAALENTERDTNLGLDVV
                     SDMEPYWEVVRSIYKPFESGLTSPTGRVYRHEIPGGQLSNLRQQAIALGLGEKFEAIED
                     MYYAADKMLGHLVKVTPSSKVVGDLALQLVGMDVDPAEFEADPRKFDIPASVINFLAGE
                     LGTPPAGWPEPFRTKALEGRTVNLADEELSAEDREALEQPGAVRRATLNRLLFPGPTKD
                     FESSRTKYGDVSVLHTRDFLYGLDQDHEHVISLGKGVRLLVTLQAISEPDEKGMRTVMV
                     TLNGQLRLLEIRDESVKSQAVETEKADTSQPGHVAAPFAGAVTVTVSEGDTVSAGDSVA
                     TIEAMKMEASITAPVGGTVSRVALADTAHVSGGDLVLVIDPQ"
     PFAM_domain     complement(13397..13570)
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_175_0020"
                     /evalue="6.10E-14"
                     /label="ctg18_175"
                     /locus_tag="ctg18_175"
                     /protein_end="1146"
                     /protein_start="1088"
                     /score="51.7"
                     /tool="antismash"
                     /translation="AVTVTVSEGDTVSAGDSVATIEAMKMEASITAPVGGTVSRVALAD
                     TAHVSGGDLVLVI"
     aSDomain        complement(13397..16825)
                     /aSDomain="TIGR01235"
                     /aSTool="tigrfam"
                     /description="pyruv_carbox: pyruvate carboxylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg18_175_0002"
                     /evalue="0.00E+00"
                     /identifier="TIGR01235"
                     /label="ctg18_175"
                     /locus_tag="ctg18_175"
                     /protein_end="1146"
                     /protein_start="3"
                     /score="1427.8"
                     /tool="antismash"
                     /translation="KILVANRGEIAIRAFRAAYELGAGTVAVFPHEDRNSIHRQKADEA
                     YNIGEEGHPVRAYLDVAEIVRVAKESGADAIYPGYGFLSENPELARAAAAEGITFVGPR
                     AEILELAGNKVEALRAARRAGIPTLDSSEPSSDKDALIAAAEKIGYPVFVKAVAGGGGR
                     GMRRVESPEQLPGALDAAMREADTAFGDPTVFIEQAVLRPRHIEVQILADNEGNIVHLF
                     ERDCSLQRRHQKVIEIAPAPQLEPEIRDALHRDAVKFAKELGYVNAGTVEFLVDTAGER
                     AGQHVFIEMNPRIQVEHTVTEEITDVDLVQSQLRIAAGETLEDLGISQDGLRVRGAALQ
                     CRITTEDPANDFRPDVGKVSAYRSAGGAGVRLDGGTLYAGAEISPHFDSMLVKLTCRGR
                     DYETAVLRARRALAEFRIRGIATNIQFLQSVLHNPDFLVGDVATDFIENHPDLLKGKGS
                     ADRGTRALNYLAEITVNKPNGERVDGIDPRDKLPHYPGDKRDEPYRSPFDGPSKHEVPS
                     GWRQVLQEKGPEGFARALREYEPLAVTSTTFRDAHQSLLATRVRTRDLLAAAPAYAHLL
                     PGLLSVEAWGGATYDVALRFLGEDPWERLRLLREAMPNIPIQMLLRGRNTVGYTPYPVE
                     VTNAFVAEAAETGVDIFRIFDALNDVEQMRPAIEAVRATGTAVAEVALCYTGNMLDPDE
                     TVYTLDYYLDLAQQCVDAGAHVLAIKDMAGLLRPEAARRLVTALRERFDLPLHLHTHDT
                     AGGQLATLLAASEAGVDAVDAAAASMAGTTSQVSGSALVAALENTERDTNLGLDVVSDM
                     EPYWEVVRSIYKPFESGLTSPTGRVYRHEIPGGQLSNLRQQAIALGLGEKFEAIEDMYY
                     AADKMLGHLVKVTPSSKVVGDLALQLVGMDVDPAEFEADPRKFDIPASVINFLAGELGT
                     PPAGWPEPFRTKALEGRTVNLADEELSAEDREALEQPGAVRRATLNRLLFPGPTKDFES
                     SRTKYGDVSVLHTRDFLYGLDQDHEHVISLGKGVRLLVTLQAISEPDEKGMRTVMVTLN
                     GQLRLLEIRDESVKSQAVETEKADTSQPGHVAAPFAGAVTVTVSEGDTVSAGDSVATIE
                     AMKMEASITAPVGGTVSRVALADTAHVSGGDLVLVI"
     PFAM_domain     complement(13748..14317)
                     /aSDomain="PYC_OADA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02436.20"
                     /description="Conserved carboxylase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_175_0019"
                     /evalue="1.80E-52"
                     /label="ctg18_175"
                     /locus_tag="ctg18_175"
                     /protein_end="1029"
                     /protein_start="839"
                     /score="178.1"
                     /tool="antismash"
                     /translation="VYRHEIPGGQLSNLRQQAIALGLGEKFEAIEDMYYAADKMLGHLV
                     KVTPSSKVVGDLALQLVGMDVDPAEFEADPRKFDIPASVINFLAGELGTPPAGWPEPFR
                     TKALEGRTVNLADEELSAEDREALEQPGAVRRATLNRLLFPGPTKDFESSRTKYGDVSV
                     LHTRDFLYGLDQDHEHVISLGKGVRLL"
     PFAM_domain     complement(14402..15202)
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_175_0018"
                     /evalue="3.10E-28"
                     /label="ctg18_175"
                     /locus_tag="ctg18_175"
                     /protein_end="811"
                     /protein_start="544"
                     /score="99.1"
                     /tool="antismash"
                     /translation="AVTSTTFRDAHQSLLATRVRTRDLLAAAPAYAHLLPGLLSVEAWG
                     GATYDVALRFLGEDPWERLRLLREAMPNIPIQMLLRGRNTVGYTPYPVEVTNAFVAEAA
                     ETGVDIFRIFDALNDVEQMRPAIEAVRATGTAVAEVALCYTGNMLDPDETVYTLDYYLD
                     LAQQCVDAGAHVLAIKDMAGLLRPEAARRLVTALRERFDLPLHLHTHDTAGGQLATLLA
                     ASEAGVDAVDAAAASMAGTTSQVSGSALVAALENTERDTNLGLDV"
     PFAM_domain     complement(15485..15808)
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_175_0017"
                     /evalue="3.30E-34"
                     /label="ctg18_175"
                     /locus_tag="ctg18_175"
                     /protein_end="450"
                     /protein_start="342"
                     /score="117.3"
                     /tool="antismash"
                     /translation="QCRITTEDPANDFRPDVGKVSAYRSAGGAGVRLDGGTLYAGAEIS
                     PHFDSMLVKLTCRGRDYETAVLRARRALAEFRIRGIATNIQFLQSVLHNPDFLVGDVAT
                     DFIE"
     PFAM_domain     complement(15854..16486)
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_175_0016"
                     /evalue="7.90E-71"
                     /label="ctg18_175"
                     /locus_tag="ctg18_175"
                     /protein_end="327"
                     /protein_start="116"
                     /score="238.0"
                     /tool="antismash"
                     /translation="KVEALRAARRAGIPTLDSSEPSSDKDALIAAAEKIGYPVFVKAVA
                     GGGGRGMRRVESPEQLPGALDAAMREADTAFGDPTVFIEQAVLRPRHIEVQILADNEGN
                     IVHLFERDCSLQRRHQKVIEIAPAPQLEPEIRDALHRDAVKFAKELGYVNAGTVEFLVD
                     TAGERAGQHVFIEMNPRIQVEHTVTEEITDVDLVQSQLRIAAGETLED"
     PFAM_domain     complement(16505..16834)
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_175_0015"
                     /evalue="4.50E-39"
                     /label="ctg18_175"
                     /locus_tag="ctg18_175"
                     /protein_end="110"
                     /protein_start="0"
                     /score="133.5"
                     /tool="antismash"
                     /translation="MFSKILVANRGEIAIRAFRAAYELGAGTVAVFPHEDRNSIHRQKA
                     DEAYNIGEEGHPVRAYLDVAEIVRVAKESGADAIYPGYGFLSENPELARAAAAEGITFV
                     GPRAEI"
     CDS             17038..17874
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 146.1; E-value: 2.3e-44)"
                     /gene_kind="other"
                     /locus_tag="ctg18_176"
                     /transl_table=11
                     /translation="VQIVSISSLKGGVGKSSVVLGLASAALDARIPTLVVDLDPHGDAS
                     TALGVHARAGHEVGTVLRRPRKGALASVAEASPWTTHPITPDTSTAGPRAWAPDAARTT
                     RVPVLDVAPGSAASSHLDHAAYRPKDLKRLETALRGLDRYELVLVDCPPTLSALTRMAW
                     AASHKVLSVAEPSLFSVAGTKRTMSALAQFESSRIWAVPEAGVVINRVRNASQEQQHRL
                     RELRDLFGPLVVDPVLPDLPVVQQAQGAAWPVHRWPGAEAAEIAGRFTAVLEGLTR"
     PFAM_domain     17041..17619
                     /aSDomain="AAA_31"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13614.8"
                     /description="AAA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_176_0021"
                     /evalue="5.00E-18"
                     /label="ctg18_176"
                     /locus_tag="ctg18_176"
                     /protein_end="194"
                     /protein_start="1"
                     /score="65.7"
                     /tool="antismash"
                     /translation="QIVSISSLKGGVGKSSVVLGLASAALDARIPTLVVDLDPHGDAST
                     ALGVHARAGHEVGTVLRRPRKGALASVAEASPWTTHPITPDTSTAGPRAWAPDAARTTR
                     VPVLDVAPGSAASSHLDHAAYRPKDLKRLETALRGLDRYELVLVDCPPTLSALTRMAWA
                     ASHKVLSVAEPSLFSVAGTKRTMSALAQFE"
     CDS             complement(17891..18508)
                     /locus_tag="ctg18_177"
                     /transl_table=11
                     /translation="LSNPELPLDAAQLRASSLAGGTQEMLFSDDLTALDETVGFRGPTA
                     CKAAGISYRQLDYWARTSLVEPTVRGAKGSGSQRLYSFRDILVLKVVKRLLDTGVSLQQ
                     IRSAVGALRLRGIEDLTRLTLMSDGASVYECTSPHEVIDLVQGGQGVFGIAVGRVWREV
                     EATLASMPAEHASLEGAAEAAGPFPEDELSARRARRRTKNAG"
     PFAM_domain     complement(18185..18379)
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_177_0022"
                     /evalue="2.60E-13"
                     /label="ctg18_177"
                     /locus_tag="ctg18_177"
                     /protein_end="108"
                     /protein_start="43"
                     /score="49.9"
                     /tool="antismash"
                     /translation="TACKAAGISYRQLDYWARTSLVEPTVRGAKGSGSQRLYSFRDILV
                     LKVVKRLLDTGVSLQQIRSA"
     CDS             complement(18653..19165)
                     /locus_tag="ctg18_178"
                     /transl_table=11
                     /translation="VSADVRMEIAGVRMDVPTGQPVVVLRELDGPRRLPIWLGTNEATS
                     IVFALQGIEPPRPLTHDLLLAVVRELGRSITRVVVHTVEDTVFHAAISFDDATVVDARA
                     SDALALAARTGCPILCSSAVLDEAGLVLSPDGELREQAVESPGGAEAQVREFRDFLDHV
                     DPDDFQS"
     PFAM_domain     complement(18776..19099)
                     /aSDomain="DUF151"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02577.16"
                     /description="Domain of unknown function (DUF151)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_178_0023"
                     /evalue="7.70E-37"
                     /label="ctg18_178"
                     /locus_tag="ctg18_178"
                     /protein_end="130"
                     /protein_start="22"
                     /score="125.6"
                     /tool="antismash"
                     /translation="VVLRELDGPRRLPIWLGTNEATSIVFALQGIEPPRPLTHDLLLAV
                     VRELGRSITRVVVHTVEDTVFHAAISFDDATVVDARASDALALAARTGCPILCSSAVLD
                     EAGL"
     CDS             complement(19162..19920)
                     /locus_tag="ctg18_179"
                     /transl_table=11
                     /translation="MPETGLPQTARVGIGALLRQLQPRFPDLTASKVRFLEDQGLVHPH
                     RTASGYRKYSEQDVERLTTVLSLQQERYLPLRVIRERLDRGEDPAAGAERQRPRVSVDA
                     AEPGAADAGDPPRPSSARYSLRELAARSGTEVPLLRELLTHGLIVERSGAYDEHALAVA
                     VAAGKLRGYGIEPRHLRVLRGASERVVALVDGSVAPLRTRRDPETRRRAVLRAREIAAL
                     CLSVMSAVVTTQVDDTVRSFHTPDSSGSDT"
     PFAM_domain     complement(19669..19839)
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_179_0024"
                     /evalue="8.60E-11"
                     /label="ctg18_179"
                     /locus_tag="ctg18_179"
                     /protein_end="84"
                     /protein_start="27"
                     /score="41.9"
                     /tool="antismash"
                     /translation="LTASKVRFLEDQGLVHPHRTASGYRKYSEQDVERLTTVLSLQQER
                     YLPLRVIRERLD"
     CDS             complement(19929..20372)
                     /locus_tag="ctg18_180"
                     /transl_table=11
                     /translation="MPNQENSGAQSGPETTSIQIVADVLSTAAQHKLTEGEQNAVASLP
                     PGSALLLETNGGLTGARFLLDRDEVVAGRHPACSVFLDDVTVSRRHAEFIRRNNTFEIV
                     DQASLNGTYVNSDRVNTKVLENGDEVQIGKFRFTFYHSVQNGS"
     PFAM_domain     complement(19974..20162)
                     /aSDomain="FHA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00498.28"
                     /description="FHA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_180_0025"
                     /evalue="3.00E-17"
                     /label="ctg18_180"
                     /locus_tag="ctg18_180"
                     /protein_end="133"
                     /protein_start="70"
                     /score="62.8"
                     /tool="antismash"
                     /translation="VAGRHPACSVFLDDVTVSRRHAEFIRRNNTFEIVDQASLNGTYVN
                     SDRVNTKVLENGDEVQIG"
     CDS             complement(20405..20812)
                     /locus_tag="ctg18_181"
                     /transl_table=11
                     /translation="MCPKLTGMTNIPAELAYTAEHEWVQDLNDDSTFKVGITDHAQSEL
                     GEVVFVQLPEVGDSVTAGDVVGEIESTKSVSDLFAPVSGEIVSVNDELSDTPGLLNDAP
                     YEAGWLFTVRVESQDATADLLDAQAYQQLLD"
     PFAM_domain     complement(20411..20770)
                     /aSDomain="GCV_H"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01597.21"
                     /description="Glycine cleavage H-protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_181_0026"
                     /evalue="4.30E-41"
                     /label="ctg18_181"
                     /locus_tag="ctg18_181"
                     /protein_end="134"
                     /protein_start="14"
                     /score="139.7"
                     /tool="antismash"
                     /translation="LAYTAEHEWVQDLNDDSTFKVGITDHAQSELGEVVFVQLPEVGDS
                     VTAGDVVGEIESTKSVSDLFAPVSGEIVSVNDELSDTPGLLNDAPYEAGWLFTVRVESQ
                     DATADLLDAQAYQQLL"
     aSDomain        complement(20411..20785)
                     /aSDomain="TIGR00527"
                     /aSTool="tigrfam"
                     /description="gcvH: glycine cleavage system H protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg18_181_0003"
                     /evalue="6.20E-45"
                     /identifier="TIGR00527"
                     /label="ctg18_181"
                     /locus_tag="ctg18_181"
                     /protein_end="134"
                     /protein_start="9"
                     /score="150.4"
                     /tool="antismash"
                     /translation="NIPAELAYTAEHEWVQDLNDDSTFKVGITDHAQSELGEVVFVQLP
                     EVGDSVTAGDVVGEIESTKSVSDLFAPVSGEIVSVNDELSDTPGLLNDAPYEAGWLFTV
                     RVESQDATADLLDAQAYQQLL"
     CDS             20938..22377
                     /locus_tag="ctg18_182"
                     /transl_table=11
                     /translation="VPITEAFRQAAIRVHTHGSRIRRTVPTMRSRRDPLHVHELTPGRS
                     ARLILSAFLLALLTGTGLLMLPLATVAPGSTDVITAAFTATSALCVTGLITVDTATYWT
                     PFGQVVIICLIQVGGLGVMTFTTMLGILLSRRLGLSARLLTSAETKSGGGARLVVARIV
                     GTTLVIEGTAATILFLRFLLHYDYSVGTALWHGVFHAVSAFNNAGFALYTLNVMDFSGD
                     AVVLLTLSSCVILGGLGFPVLAELRRHIRIPHRWSMNTRLVLFATPLLLLSGTVFILVL
                     EWSNPATLGSQSPAVKVLNAFFQSTISRTAGFNSIDISQMHPVSWLGMDILMFIGGGPA
                     GTAGGLKVTTFGVLFFIALTEIRGGAAVPVLGKQLSRSVQREAITVVVLAAGAVIGGSM
                     LLMLTDQSLGLDRVLFEVVSAFSTVGLSTGITPALEPFAQCVLIALMVMGRLGPVTVAA
                     AIAYGRRPPSFGLPKERPLIG"
     PFAM_domain     21154..22311
                     /aSDomain="TrkH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02386.18"
                     /description="Cation transport protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_182_0027"
                     /evalue="2.20E-50"
                     /label="ctg18_182"
                     /locus_tag="ctg18_182"
                     /protein_end="458"
                     /protein_start="72"
                     /score="171.7"
                     /tool="antismash"
                     /translation="PGSTDVITAAFTATSALCVTGLITVDTATYWTPFGQVVIICLIQV
                     GGLGVMTFTTMLGILLSRRLGLSARLLTSAETKSGGGARLVVARIVGTTLVIEGTAATI
                     LFLRFLLHYDYSVGTALWHGVFHAVSAFNNAGFALYTLNVMDFSGDAVVLLTLSSCVIL
                     GGLGFPVLAELRRHIRIPHRWSMNTRLVLFATPLLLLSGTVFILVLEWSNPATLGSQSP
                     AVKVLNAFFQSTISRTAGFNSIDISQMHPVSWLGMDILMFIGGGPAGTAGGLKVTTFGV
                     LFFIALTEIRGGAAVPVLGKQLSRSVQREAITVVVLAAGAVIGGSMLLMLTDQSLGLDR
                     VLFEVVSAFSTVGLSTGITPALEPFAQCVLIALMVMGRLGPVTVAA"
     CDS             22471..23160
                     /locus_tag="ctg18_183"
                     /transl_table=11
                     /translation="MFGSQLSEISRRGMSDAVAVIGLGRFGGALALELMRNETDVLGID
                     HDQATVQRFNGKLTSVVRADATDEDVLRELSVDEFERVVVGIGSNIEASILTASRLVKF
                     GCPGIWAKALTEPHAEILTQLGVQNVVNPESDMGTRAAHLVQHRILDFVPIDDGHALVR
                     CTPPEPIQQRPMDLLNVRQRLGVSVVAVCRPGGQWEPIEAGTMLYDDDQILVTGPTRKV
                     EHFSNLT"
     PFAM_domain     22522..22869
                     /aSDomain="TrkA_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02254.20"
                     /description="TrkA-N domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_183_0028"
                     /evalue="5.40E-24"
                     /label="ctg18_183"
                     /locus_tag="ctg18_183"
                     /protein_end="133"
                     /protein_start="17"
                     /score="84.8"
                     /tool="antismash"
                     /translation="VAVIGLGRFGGALALELMRNETDVLGIDHDQATVQRFNGKLTSVV
                     RADATDEDVLRELSVDEFERVVVGIGSNIEASILTASRLVKFGCPGIWAKALTEPHAEI
                     LTQLGVQNVVNP"
     CDS             complement(23278..24276)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178:cobalamin synthesis protein/P47K family protein
                     (Score: 183.3; E-value: 1.2e-55)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_184"
                     /transl_table=11
                     /translation="VTRTVPVLILTGYLGAGKTTVLNHVLATGGGRVGVVINDFGDVNV
                     DAGLVAGHVTEPLSIAGGCLCCLQDPAQLDDALRTLSRPALDLDAIVIEGSGIAEPPAL
                     LQLVLGSTVDSVRFGGLVEVVDAAHVPHAEQRGWDLAQHVKAAALVLLTRTDVAEPHES
                     ARVRERVAQANPHAMVLEAPWGAVDPRLFFDAAERAVPEGGQLPLWELGTAGGHAHHVH
                     HRAASLDVPATVDPAALADLLEDPPDEVYRVKAVVDVATVRGARRYVAHSVAGFVTVER
                     APRPAGAAPHSVVVAIGPENDAAVPVDLTGIVNRSPAPATARELRRLTRFL"
     PFAM_domain     complement(23368..23595)
                     /aSDomain="CobW_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07683.16"
                     /description="Cobalamin synthesis protein cobW C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_184_0030"
                     /evalue="7.80E-07"
                     /label="ctg18_184"
                     /locus_tag="ctg18_184"
                     /protein_end="303"
                     /protein_start="227"
                     /score="29.0"
                     /tool="antismash"
                     /translation="LDVPATVDPAALADLLEDPPDEVYRVKAVVDVATVRGARRYVAHS
                     VAGFVTVERAPRPAGAAPHSVVVAIGPENDA"
     PFAM_domain     complement(23737..24261)
                     /aSDomain="cobW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02492.21"
                     /description="CobW/HypB/UreG, nucleotide-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_184_0029"
                     /evalue="6.50E-36"
                     /label="ctg18_184"
                     /locus_tag="ctg18_184"
                     /protein_end="180"
                     /protein_start="5"
                     /score="123.7"
                     /tool="antismash"
                     /translation="PVLILTGYLGAGKTTVLNHVLATGGGRVGVVINDFGDVNVDAGLV
                     AGHVTEPLSIAGGCLCCLQDPAQLDDALRTLSRPALDLDAIVIEGSGIAEPPALLQLVL
                     GSTVDSVRFGGLVEVVDAAHVPHAEQRGWDLAQHVKAAALVLLTRTDVAEPHESARVRE
                     RVAQANPHAMVL"
     CDS             complement(24412..25560)
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-376). E-value:
                     2.7e-34. Score: 110.7. Matches aSDomain:
                     nrpspksdomains_ctg18_185_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 200.9; E-value:
                     5.3e-61)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_185"
                     /transl_table=11
                     /translation="MTTADQMPSLRRRTSTKWRSYPEDVLPMFIAEMDFPTPPPVKAAL
                     EAAIENNDTGYAATADRGAAQAYADFAAARWGWRPDPERIMYTTDVTVVIVEALRRLIR
                     PGEGVVLTPPVYAPFYHLVAEAGGRPVEVPLQDDGAAYRLDLPGIDAALAAGARAVLLC
                     NPHNPLGLVHAHEELTELAEIVERRGAHVVSDEIHAPLTHRGATFTPYLSVSDAARRHG
                     VAAASGSKAFNLAGLKAAMFVVDSEPMAQWLATVPDAVSYRTGIMGLLATQEGFRHATD
                     WLDATIEVIESNIALLERQLADKLPQVRFRRGSATYLAWLDMRDLDWGDDPAEHAAEHA
                     KVALSSGPTFGAGGAGFARMNLACSPDTIVEAVDRLSSAARG"
     aSDomain        complement(24433..25452)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_185_Aminotran_1_2.1"
                     /evalue="2.70E-34"
                     /label="ctg18_185_Aminotran_1_2.1"
                     /locus_tag="ctg18_185"
                     /protein_end="376"
                     /protein_start="36"
                     /score="110.7"
                     /tool="antismash"
                     /translation="TPPPVKAALEAAIENNDTGYAATADRGAAQAYADFAAARWGWRPD
                     PERIMYTTDVTVVIVEALRRLIRPGEGVVLTPPVYAPFYHLVAEAGGRPVEVPLQDDGA
                     AYRLDLPGIDAALAAGARAVLLCNPHNPLGLVHAHEELTELAEIVERRGAHVVSDEIHA
                     PLTHRGATFTPYLSVSDAARRHGVAAASGSKAFNLAGLKAAMFVVDSEPMAQWLATVPD
                     AVSYRTGIMGLLATQEGFRHATDWLDATIEVIESNIALLERQLADKLPQVRFRRGSATY
                     LAWLDMRDLDWGDDPAEHAAEHAKVALSSGPTFGAGGAGFARMNLACSPDTIVEAVDRL
                     "
     PFAM_domain     complement(24433..25452)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00155.23"
                     /description="Aminotransferase class I and II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg18_185_0031"
                     /evalue="8.70E-32"
                     /label="ctg18_185"
                     /locus_tag="ctg18_185"
                     /protein_end="376"
                     /protein_start="36"
                     /score="110.8"
                     /tool="antismash"
                     /translation="TPPPVKAALEAAIENNDTGYAATADRGAAQAYADFAAARWGWRPD
                     PERIMYTTDVTVVIVEALRRLIRPGEGVVLTPPVYAPFYHLVAEAGGRPVEVPLQDDGA
                     AYRLDLPGIDAALAAGARAVLLCNPHNPLGLVHAHEELTELAEIVERRGAHVVSDEIHA
                     PLTHRGATFTPYLSVSDAARRHGVAAASGSKAFNLAGLKAAMFVVDSEPMAQWLATVPD
                     AVSYRTGIMGLLATQEGFRHATDWLDATIEVIESNIALLERQLADKLPQVRFRRGSATY
                     LAWLDMRDLDWGDDPAEHAAEHAKVALSSGPTFGAGGAGFARMNLACSPDTIVEAVDRL
                     "
     CDS             complement(25593..26066)
                     /locus_tag="ctg18_186"
                     /transl_table=11
                     /translation="MSSVITTYLQDHHAGSAAGVAAFRRVAEFHGDAEVREAVGRMAED
                     IAQDQVALEEVMASVGVQPAALKDLPARAAERLARLKPNERISRRSPLSDIEELEALVA
                     AVHAKRLGWRMLLEAPDDRLDRDLLRRLCERAEEQEKTLDLLRLGQAHKLTSS"
ORIGIN
        1 ccgctcccca ctccccctcg cggccgtcca ggctgagctg gagggcgtgg ccggatccca
       61 cgagcttctc ggacctgaca cctatcagcc gcaccgcctg cgggcgcggc cccagtgctt
      121 cgagcagacc ggcggcctcc gtgtagaggt cgtgggcgga ggccaccggg tggcccaggg
      181 tgcgcgagcg ggtgatcgtg gtgaagtccg cgtaccgcag cttgagcccc acccgtcccg
      241 tgagcagccc gtggcgtctc agccgggccg ccgtgtcgtg gctcagcccg agcaggacgc
      301 gcttgagctg ggcggtgtcc gccacgtccg tctggaacgt gcgttcggca cccaggctct
      361 tctcctcccg cgcgggtgtc acggggcgcg ggtcgtggcc gagggcgagc tgctgcaggt
      421 gtgagcccgc ggccaccccc acgagggcgt gcagccgcgg cagcggggtg tccgcgatgt
      481 cccccaccgt ggcgagtccc gccgcgtgaa gggtctcgga cgtgcgcctg cccacgcccc
      541 acagccgctc caccggcagg tgggcgagga acgcccgggt gtgctccggg gccaccacga
      601 gcagcccgtc cggcttgcag tgcgccgagg cgatcttggc caccgtcttg ttctctccga
      661 tccccacgga cgcggtgagc ccggtccgct cgtggatggt gcgccgcagc cgccgggcga
      721 tctccacggg tggcccgcag cggcggatgg cgcccgagac gtccacgaac gcctcgtcca
      781 cgctcagctg ctccacccgg tccgtcacgg agcggaagat gtccatcacg atcgccgagt
      841 agtgggcgta ggcctcccgg tggggttcca gcagcactgc cgaggggcac ctggcccgcg
      901 cctgggagac cggcatggcg gagtgcaccc cgtactcgcg ggcctcgtag gaggccgaga
      961 gcaccacgga gcgcggcccg gaacccgcga cgatcactgg gcggccgcgg tgctgcggtg
     1021 cgctgagcag ctcgaccccc acgtagaaca tgtccatgtc cacgtggagg atcgcgcagc
     1081 gccggtactc ctccagctgc tgcgggctcg gaccgcccat cgcgtgcgcc tcccgtctcc
     1141 gctcctccgg gacggacccg gagatccccg ccgagtcggg gccgggacgg agcccagcct
     1201 agggttcggc tccgacacgc tgaacggagc ccgtgacgtg cggctaggct gggcgggccg
     1261 gtccgcggac cccgcgggcg agcccggccc gcgtggcccg gcacacgcca cccctcccag
     1321 caaaggtgcc ccggaatgac ctccacggac gatcccgccg ccactgccgc cgcgcaggac
     1381 gcccagttct ccgcccggct cgacaccgcc atccgcgagt tcttcgccgc cgagcgggaa
     1441 cgggtcaccg ccatctcccc cgacgccacg cgcctggtgg cggccatcgc cgacctcacg
     1501 gacggcggca agcggctgcg cgcgcgactg tgccactggg gctggtgcgc cgcgggcggg
     1561 gaggcgggca gcgacgtcgt ggtggccgcg gcggcatccc tcgaactgtt ccagacggcg
     1621 gcgctgatcc acgacgacgt cctggaccgc tcggacaccc gccgcggcag gccgagcgtc
     1681 cacagggtct tcgaggccgt ccaccgcgag gccggctggg ccgcggatcc cgagcacttc
     1741 ggcgtcggtg ccgccgtgct caccggggac atgagtctgt ccttcgcgga gcagctcttc
     1801 gccgaggccg ccgcaggtgt ggcccctgcg gcgggtgccg cggcgcggca catcttctcg
     1861 agcatgcgca ccgaggtgat ggccgggcag tacctcgaca tccacgcgga ggtcgccccg
     1921 ccgtcgcacg acgccgcggt gcagctcgag cgcgccatga cggtgctgcg ctacaagtcc
     1981 gccaagtact cggtggagca cgccgtggcc atcggtgccg ccctggccgg tgcggacgac
     2041 gagttcctgg ccgcgtgcgc cgcgttcacc cttcccctgg gagaggcgtt ccagctgcgc
     2101 gacgacgtcc tgggtgtgtt cggcgacccg gagaccacgg gcaaacccgc gggggacgac
     2161 atcagggagg gcaagcgcac cgcgctgatc gcgctctgct ccgccgggtg ctcccccgcg
     2221 cagcggcagt ggctcgaatc ggtgctgggc agcgaacggc tcaccgagga ggacgtggcg
     2281 cgggtgcgtg acctcatgcg ctccagcggc gcccacgagc gctccgagca gctcatcgcg
     2341 gacctcgtgg cgtcctcgga cgcggcgttg gcggtgctgc ccaccggcga ggtgccccgc
     2401 gcgggactgc gggcgctggc ggacgcggcg gtgcgccgca cacgctgagt caccccggag
     2461 caggggccgc gagccccgcg ccgcgggcgg ggtccgggca cgccgcgggc cggcgccctc
     2521 cgctgttctc agtcggcccg gttcaccagc cgagcgcctg tgcccggcgc cgcacctcgg
     2581 tcttctgacc gcggcgcagc gcgtcgatcg ggcggccagg gagggactcg tcctcggtga
     2641 acagccagcg gatggcctgc gcatccgtgt aggccgcgtc acgcagcacc gccaccgtgc
     2701 ccttgaggga gtccacgggg tgcgagccgt ccatgaacgc cgcgggcacc acgcgcacgc
     2761 ggtcctcggg gcggcgcacc tccagcaggg agccgtcgtc catgagacgg tgcacccggg
     2821 tgatctggat gtccatggcc tcggcgatgt cgggcaggtg cgtccactcg cccacgaggg
     2881 cgtcgagttc ggcgaattcc tggggcgtga gatcggttgc gtagttcacg cgcactactc
     2941 tgccacgccg ccgcaggctc gcagaacccg ggtgggcggc gcggggtcgg gtaatctggc
     3001 agcacagcgt gcggcgcccc cggtgccccc gatcgtcccc tttcccccat gccgaggcag
     3061 gtatcgcgaa catgccggtt gagccgcccc acgaccgcca caccccccgc ggccagtggt
     3121 cccgccgcgc cgctcacggt tctgtggccg ccctgacggc actcaccgcg ctgggaacca
     3181 tgggggcggc ccaggccgcg cccgccaccc cgcagaccgt ccaggtggcc cagcagcatg
     3241 cgggacaggt gaccgttgcc cccggggact ccgtgtggtc cctggccacc cggcacggcg
     3301 tgagcgtctc ggagctcatg gccgccaacg acatcccggc gcacggcatg atccgccccg
     3361 gccagcggct gcgcatcccc gagacctcga accccgcgga cggggaggcg gcccccgccc
     3421 gggggaagaa cgccccgaag ccgtcccccg cgggcggcag ctccacgccc gcacccgccc
     3481 gaacgcacca cagcgtggcc gccggggaca ccctgtggga cctcgccctg cgctacgagg
     3541 tgagcgtggg cgacctcctg cgggccaact cgctctcccc gaacgacgtg ctgcgccccg
     3601 gacgcaccct cgtgatcccc ggtgcggcgc ccgagcacag ggcggacgcg gcggtgtcgt
     3661 cccccgcgcc cgagcgctcc gggaccgcgg caccggacga ggaacccgcc gtgggagact
     3721 ccttcgcggg ccgccagtac ccccgggagg tggtggactc ggccaacgcg caccacgagc
     3781 agctgcgctc gcgcgccgtg ccgccgccgg cccagatccg gcagatggtg gaggccaccg
     3841 cccgcgacat gggcgtggac ccggccctcg cgctggccca cgcgtcccag gagtcggggt
     3901 tccgccacga cgtcgtgtcc ccggcggacg ccgtgggcac catgcaggtg gtgccggccg
     3961 ccggcgactg ggcctccgcc atggtgggcc gcgacctgga cctgctggac ccgcaggaca
     4021 acatcaccgc gggcatggcc atcatccggg cgctgcagga cagggccccg gacaaggcca
     4081 ccgggatcgg cgcctactac cagggactgc acggcgtgac cacgtacggt atgtattccg
     4141 acaccaaggc atacgtcaag gccgtgagcg cacaggaacg gaaatttgcc cagtagcagc
     4201 atgaacgacc accgtgtggg ggccctgctc gagaaccgct accgcgttct ccggcggatc
     4261 gcccacgggg gaacggcggc cgtctacgag ggcctggacg agcgcctcga ccgccccgtg
     4321 gccctgaaga tcatgcaccc gcacttcgcg gacgaccccc gcttcgtcac ccgggccgaa
     4381 cgcgaggcga aggccgccgc ccggctccac gacccccacg tggtggccgt gctggaccag
     4441 gggcgcaccg acgacggcgt gctgtacctg gtgctcgagt tcgtggacgg gcccaccctg
     4501 cgcgaggtcg tcgcacgcga ggcgccgatg gacccgcacc gcgccctcga gctgctcgtg
     4561 ccggtgctcc ggggcctcgc cagggcgcac cgcaccggcc tggtgcaccg cgacgtcaag
     4621 cccgagaacg tcctgctcac cgcggacggg caggtgaagg tcgcggactt cggcctcacg
     4681 cgcgccgtgg acgaccacac gaccagcacc accgtgctgg gcaccgtggg ctacgccgcg
     4741 cccgagctgg tgggcgacgg ccccgtggac cagcgcagcg acgtgtacgc cgtgggcatc
     4801 atggcctacg agatgctcac gggctcccgc ccgtacacgg gcacggccct gcaggtcgcc
     4861 accgcgcacg tgagccggga cgtgcccgcc ccgagcggga tcgccgcggg agtgcccccc
     4921 gccctggacg agttcgtgct gcgggccacc tcccgcgacg cgtcccggcg ccccgcggac
     4981 gccgccgagc tgctggacct cgccctcgcc gtccgacgct ccctgcccgc tcccgcggat
     5041 ccgctgctcc tgggggaggc ggccaccgag gtcctcgccg gagggcccca ctctcccacc
     5101 ggccatccgg aggaggcacc caccgaggcc gttggcgccg gcaccgcgga cggctccggg
     5161 gaggaggcca ccgaggccat gggccccgga gggcaggacc tgcccaccga ggccatcggc
     5221 acccctacgc aggaggctcc cacggaggcc ctggggacgc cgtggcacga ggcccccacg
     5281 gaggctctcg gcaccgggcc gcacgaggcc cccacggagg ctctcggcac cgggccgcac
     5341 ggggccccca ccgaggtcgt gggcgcgaac gccggggtgc cccccggagg tcacggcacc
     5401 ccgatcctgc ccgcctacga ggaggacgcc acgggcacgg tggcgctcac ccaggtgggg
     5461 tccacggcgc accgctcgcc gcacgagccg cgtgtgcgcc tgaacccccc ggcccagccg
     5521 ctgcacgtgg ccctcgtgct cgtggtgttc gcgctgctgc tcacggtggc ggcgttcctg
     5581 ggctggtggc tgggctccgc gcccgggacg gccaccgcca cggtcccccc ggtggcgggg
     5641 caggacaccg cggcggccga gcgcacgctg aacgccgcgg ggatctccaa cgtgggcgtg
     5701 agcaccaccc cgagctgcga ggcgcccgag ggcacggtga tctccaccga tcccgccgcg
     5761 cccgccaccg ttcgggggat cgagcaggtc aatctcctgg tctcctccgg tcccgcccag
     5821 gtggacgttc cggccctgac cgggatgtcg gccgacgacg ccggggcggc cgtgagcgcc
     5881 gcgggtctcg gtctcggcgg ggtcacccgg gagtactcga cgcggccggc gggcaccgtg
     5941 ctgtcccagt cccccgaggc gggcagccgc gtggacgagg gaacgcagat gtccctcacc
     6001 gtggccacgg actcaccgca gggaccggtc ccgaacgtgg tgggcaagga cgccgagacg
     6061 gcgcggacca ccctggagga gcagggctac accgtgcaga tcgactcccc cgtgggctcg
     6121 cacctgaacc gcgtggtgcg ccaacgcgag gacggcgaca ccgtggtgct caccgtcctc
     6181 tgagcccccg cgcggctccc gaccggccgt cggcacagga cgcccaggtg cccgcgccgg
     6241 ccggccgggg cccggcgcgg ggacacgacc gtcagtgctg cgcggagagg tactccgcca
     6301 ccaggaacgc gatctcgagc gactgcttgt ggttgagccg cggatcgcag agcgtctcgt
     6361 agcgctcggc gaaggaggac tcggccacgg ggtccgagcc accgaggcac tcggcaacgt
     6421 cgtcaccggt catctccacg tggatgccgc cggggaacgt gccgagctct cggtgcacct
     6481 cgaagaagcc gcgcacctcg tccaccacgt cctcgaagtt gcgggtcttg taccccgacg
     6541 ccagggacac ggtgttgccg tgcatgggat cggtgaccca gacgggcttc gcaccggagt
     6601 cctcgaccgc cttgatgacc gggggcagct tctcccggat gttcttcgcg cccatgcggg
     6661 tgatgaacgt gagacgtccg ggctcgcggt cgggatcgag agcgtcgatc aggcgcagtg
     6721 cgtcgtcgcc ggaggtgccg gggccgagct tgacgccgat cgggttgcgc agcctcgaga
     6781 gcaggtccac gtgggcgccg tcgaggtcgc gcgtgcgctc gccgatccac aggaagtggc
     6841 ccgacgtacc gtacggcagg tgcgtgcggg agtcgatgcg cgtgagcgcc cgctcgtagt
     6901 ccagcaacag ggcctcgtgg cccgcgaaga actcggtggt cttgagggcg tcgaagtcgg
     6961 agccgcacgc ggccatgaac ttgacggcgt ggtcgatctc gcgcgccatc gactcgtacc
     7021 gggcgtaggc ggggttcgcc gcgaaaccca tgttccacgc gtgcacgcgc cgcaggtccg
     7081 cgaaaccacc ctgggtgaag gcgcggatca ggttcagggt ggaggccgag gtgtggtagc
     7141 cgcgcagcat ccggcgggga tcgtggacgc gggactcctc ggtgaagtcg aagccgttga
     7201 ccatctcacc gcggaacgag ggcagggtga cgccgtcgcg ggtttcctcg ttggaggagc
     7261 gcggcttgga gaactgcccc gccatccgcc ccatcttcac cacgggcatg gacgcgccgt
     7321 aggtgagcac caccgccatc tgcagcagcg tgcggacgcg gccggagatc ttgtccgcgg
     7381 tcgctcccgc gaacgtctcc gcgcagtcgc cgccctggag gaagaaggcc tccccgttgg
     7441 ccacctgggc gagacgttcc cggagggtgt ccacctcccc ggcgaagacc aggggcggga
     7501 ccgcgcccag ctcctggatg gtggccgcga agtccgggtg ctccgcccac tggggatgct
     7561 gcccgatgct ccttccccgc cactcgtcga gtccggggta gtccgccgcg ctcggcgagg
     7621 gggtcatcac ggatcggagc tgttcaggca gggtctcgga actcattccc ccagtctagg
     7681 ccgtggggcc aggggtcccg tcatccgccc cggagtccgt cccgccatgc ggacggcggt
     7741 gcagggtgtc gttgaggtga ccggcctgct gggacaccgc gtccgtgacg gaacggccct
     7801 tgtccctggt ggcctgggcc acctccttgg cctgcgccag cagtgcggag gtcttcccgt
     7861 ccgccatccg gcgcttgtgc tcggtggcgt agacgtccgc aacctcctgg ccggacagcc
     7921 gctggatggc ggccatgatc tcgtccgtca ctcgccgcag cgtggcgtgg tccacctgct
     7981 gtcccctcag gtgggagaag tccatgggct cgccgaagat cgtggtgatc cgggcgcggc
     8041 gggggtccgg aaaacgggag cccagcggct gcatcttgtc cgtgccgatc atggccacgg
     8101 ggatcacggg ggctccggac tccagggcga ggcgggccac tcccaccttg ccgcggtaga
     8161 gccgcccgtc cggggagcga gtgccctcgg ggtagatgcc cagcagcttg ccctcggcca
     8221 gggcctggcc ccccgcgctc agggacttgg cgctggcctg accgccgcgg cggtccatgg
     8281 ggatctggtt gatcgccttg aagaacgccg ccgtgaggcg ccccttgagg ccaggggtgt
     8341 tgaagtactc ggacttggcc aggaagaaga cctgccgggg aacggccacc ggcatgaaga
     8401 tggtgtccgg caccgagagg tggttgctcg ccaggatcgc ggggccgtgg gacgggacat
     8461 gctccagacc gatcacggtg ggtcggcata ccctgttgac cacgggtgcc accacgtagt
     8521 tcctgaggaa catgtacacc atgagcgtgt gccctttcgt cggcgcgggt cgcgggcccg
     8581 ttcggcccgt tcggcgggac gcccggtcca gtggccccgg tcggtcccgg gcgattctct
     8641 catgcgggtg gcggcggctg gcacaatggc gccatgtcat cggatctgca acgacacgac
     8701 tccctgaacc tgcccggcac ctcctccgtg ggggtcctgg tgctccacgg cttcagctcc
     8761 acgaccgctt ccgtggcgga ctgggcccgg gcgatccaca cggccaccga cgccgccggc
     8821 gcggctcccg gggtgagggt gccgctgctg ccggggcacg gaacccactg gcaggacctc
     8881 gcggcgcagc cgtggcaggc gtggcgcgac gccgtggacg agcactactg gcagctgcgg
     8941 cagcggcacg agcacgtggt cgtgtgcggg ctgtccatgg gcggggccct cgccctgcac
     9001 accgcggccc gccgcgaggt cgccggcgtg ctgctcgtga accccgcgct gtccctggtg
     9061 aacagggcgg cgcggttcag ccgggtgctc gcctccgccg tgccgtccta cgcggggatc
     9121 ggcagcgaca tccgcaagga gtccgtcctg gagtccgcgt acgaccgcac gccgctggcc
     9181 gcggtggcgc agctcaacgt gctcatgcac cgcacggtgc agatgctgcc ggcggtcact
     9241 gccccggcga tcgtgttccg ctccgaggtg gaccacgtgg tctcgggtgc ctccgcggac
     9301 ctcgtggcgc agcgcacgcg cggtccggtg cgggtggttc ccctgccgga cagctaccac
     9361 gtggcaaccc tggaccacga cgcgccgctg gtggagcaga cctcgcggga cgccgtgcag
     9421 cgcgtgtgcc gcggtctgcc gcttctgccg gagacggcgt gagctcccgg gacggatcgg
     9481 aggatccctt cgagagcatc atccggtcca acacgtggga cgacgtcccc ggggacgacg
     9541 aggacatgga accctgggcg gaggacctcg agtgggttcc ccgggagcag cccccggagg
     9601 acgtccccga agagctggac gaggtcgatg aggacgccgt ctacgatccc gatcccggcc
     9661 cggtgacggg cggggtgtcc cccgccatgc tgcgcgcgct gagcgtgctg ctcgcggtgc
     9721 tcgtgatcat gctggggctc gccgtgctgc ccggtccgct gcccggcgtg gtctggggcg
     9781 cgggtctcgc cgggaccgtg gccgggctgt tcctcgtgtt tggtgccctg ccggaggact
     9841 cccccgagga cgacgacggt gcggtcctgt gacacccgtg tcccaccgcg ggcagggcga
     9901 cacggttcga ccccgcttgt gtggacacgt ccaccaacgc cgcggtgtga aggtgaacac
     9961 accgtaaact gagactcaat ctcgccagga aggtaccccc atgagacgcg tcagtgcccc
    10021 ggccatcgtc gatcccctgc cctaccccgg catcgcccac atcctcgagg agcgtgcccg
    10081 cacgcagccg gatctggtgc tctacacgat cctcgccccg gggcgggagc gggacgtcac
    10141 cgctcgtgag ttccgcgccg aggtggtggc cctcgcccac gggatggccg cccaaggcat
    10201 ccgccccggg gaccgtgtgg gtctgctgag ccgcacccgc tacgagtgga cgctcgtgga
    10261 cttcgccctg tggtggctcg gtgccgtccc cgtgccggtc tacgacacct cctccccgga
    10321 ccagatcgcg tggatcctct cggactcgcg cgccacggcc gtgttcgtcg agacggacga
    10381 gctcgccggg cgcgtgcggg aggcccaccg catcaccccc ttcccggccg agcagcgcat
    10441 ccgggtgttc gacacggacg acgcgcagat ctccctggac gccgtggtgc gggcgggcgc
    10501 cgggcgcgag gacctgcaga ccccgtacga cggcgtgagc ctggacgacg ccgccacgct
    10561 catctacacg tccgggacca ccggaccgcc caagggctgc gagctgaccc accgcaactt
    10621 cgtggcgtgc tcccagaaca cgatccccgt ggccggggag ctcatgcacg agggagcgcg
    10681 caccctcctg ttcctgccgc tggcccacgt gttcgcccgg ttcgtggagg tcacctccct
    10741 ggacgccggc atcgcgctgg cacacacccc ggacgtctcc cagctcatgg acgacctcgc
    10801 ccggttcaag cccaccttca tcctggcggt gccgcgggtc ttcgagaaga tcctggtggg
    10861 ggcccgcttc aaggcccagg cgggctcacc cgtgaagaag ctgatcttcg agcgcgcggt
    10921 ggccacggcc gccgcatggt ccaaggcctc ccagcagggc cgcgtctccc cgtggctcgc
    10981 ggcgcgccac cgcctgtacg acaagctggt ctactccacc ctgcgcgagg ccatgggcgg
    11041 ggaggtccgc tacgccgtct cgggcggggc ggctctcggt gagcacctgg cccacttctt
    11101 caacggcatc ggcgtatacg tggtggaggg ctacgggctc accgagacca cggcgccgat
    11161 ctccgcgaac gtgccgagca tcaaccggct gggcaccgtg ggccacccca tgcccggcaa
    11221 cgaggtggcc atcgcggagg acggcgagat cctggtgcgc ggcgtgaacg tcttcgagcg
    11281 ctacaacggg ctgcccgaga agaccgccga ggctttccac gacggctggt tcgccaccgg
    11341 agacctgggg cacctggacg acgagggcct gctgaccgtc accggccgca agaaggagat
    11401 catcgtcacg gcgagcggca agaacgtgat tcccaccatg ctggaggatc ccatccgcgc
    11461 gtccgccacg gtggggcaga tcatggtggt gggtgagaac cgcccgttcg tggccgccct
    11521 gatcacgctc gaccccgaga ccctggccaa cgtcctgccc accctcgggc tggacccggg
    11581 cctgagcatc gcggaggcgt cccgggagaa ggccgtgatc gagcacgtgc agcggatcgt
    11641 ggaccacgcg aacaccaagg tctcgcgcgc tgagggcatc aaggccttcc ggatcctgga
    11701 ccgcgacctc accgtggagg acggctacct cacgccgtcc ctcaagctca agcgggccgt
    11761 ggtcgccgag gacttcgcgg acgtcatcga cggcatctac gccaggtagc ccccgcgacc
    11821 acgacgccgc ccgcaccctc gagccccggg gcgcgggcgg cgtcgtcgtt cagtccgcgc
    11881 gctggcccgg gacgtccagc ccgagcagcg cgttctccac gacctcggcg agggcggggt
    11941 ggatccagta ctgtccgcgc gccatctcgt ggacgcgcag cccgaaggcc atgccctgca
    12001 cgagcggctg gatcaggttg gacgcctccc ggccgatcag gtgcgccccg agcagctccc
    12061 cggtgccgga gtccgcgatg agcttgcaga gacccacgtg gtcctccatg gcccacccgt
    12121 acgccacgtc gccgaagtcc tgcaccttga cggtgatctc gtggcccgtg cgctccgccc
    12181 aggcccgcgc ggcacgctcg gtcatgccca cggacgcgat ctgcggctcc gtgaagaccg
    12241 cggcgggcac gaagcggtgg tcggtgctgc gctggtcgtc cgggtggacc acgttgtggg
    12301 agaccaccct ggcctcggcg ttcgccacgt gcttgagctg gtgcggggaa gacacgtcgc
    12361 cgagtgccca gaggccttcg accggctgcc cgcccgagag cacccgctgc tgctcgtcca
    12421 cggcgagcag cccgcgctcg gtgacgtcaa ggtgggccgc tccggggttc agggtgtccg
    12481 cgttggggat gcgcccggtg gcgagcagca ccacgtccgc ggtgcgctcc cactgcttcc
    12541 cggagccgtc gctcgcgtcc gccgagacct tgagccggcc gtcctcggag gtcaggatgc
    12601 ccgtgaggct ccaccccagc tgaaggtccc agtgcgcggc ggcctcacgg gtgaagcgct
    12661 cggcgatcgt gtcgtcgtgg gcgcgcagca ggcgctgcga gcggttgagc tgcgtgaccg
    12721 acgcgccgag accctggaac acgtggcaga actcggcggc gatgtagccg ccgcccacca
    12781 ccaccacgtc ccgcggcagc tccggtatgc gcatcaccgt gtccgacgtg tgcacccccg
    12841 gcagatccgt gccgggcacg tccgggacgt gcacgcggga gccgttggcc agcacgatcc
    12901 ggggtgcggt gatccgctcc cccgagtccg tctccagcac gcggggctcc acgaagtgca
    12961 cgtactcctg gatgaccgtg acgttctcca gcgaacgccg gtagtccagc ccgccctcgg
    13021 agatcgcgtc gatgcgaccg aagatccggt cccgcatccc cggccagtcc acgccgtcga
    13081 ccgtggcgtc cagcccgagc cgcccggcgt cccgtgcctg gtccgccacg gtggcgggat
    13141 acacgtacat cttggtgggg atgcagccga cgttgagaca cgtgcccccg aagcggccgg
    13201 gttccacgat ggccacgtcc aggtcccggt actcgtccgt gagcagcgag ttgcccgagc
    13261 cggagccgac gatgatcagg tcgaaagatc gcatgggccc catgctagga cgccaccccg
    13321 cacacggggt gcggggtggc gtccgttcag cccacggcgt ggccgccgtg ggaatccctg
    13381 cggatcactg ggggtcgatc accaggacca ggtccccgcc gctcacgtgc gcggtgtcgg
    13441 cgagcgccac gcgggagacc gttccgccca cgggagccgt aatggaggcc tccatcttca
    13501 tggcctcgat cgtggccacc gagtccccgg cggagacggt gtcgccctcc gagacggtga
    13561 ccgtgaccgc gccggcgaac ggcgccgcca cgtggcccgg ctgggacgtg tccgccttct
    13621 cggtctccac ggcctgcgac ttcacggact cgtcgcggat ctccagcagg cgcagctggc
    13681 cgttgagggt caccatcacg gtgcgcatgc ccttctcgtc cggctcggag atggcctgca
    13741 gggtcaccag caggcgcaca cccttgccca gcgagatcac gtgctcgtgg tcctggtcca
    13801 gaccgtagag gaagtcgcgc gtgtgcagca cggagacgtc accgtacttg gtgcgggagg
    13861 actcgaagtc cttcgtgggc cccgggaaca gcaggcggtt gagcgtggca cggcgcaccg
    13921 caccgggctg ctcgagcgcc tcgcggtcct ccgccgagag ctcctcgtcc gcgaggttca
    13981 cggtgcgtcc ctcgagggcc ttggtgcgga acggctcggg ccagcccgcg ggcggggtcc
    14041 ccagctcccc ggccaggaag ttgatcaccg aggccgggat gtcgaacttg cgggggtccg
    14101 cctcgaactc cgcggggtcc acgtccatgc ccacgagctg cagggcgagg tcccccacca
    14161 ccttggagga cggggtgacc ttgaccaggt gcccgagcat cttgtccgcg gcgtagtaca
    14221 tgtcctcgat ggcctcgaac ttctcgccca ggcccagtgc gatcgcctgc tgccgcaggt
    14281 tggagagctg accgcccggg atctcgtggc ggtacacgcg gcccgtgggg cttgtgagcc
    14341 cggactcgaa gggcttgtag atcgagcgca cgacctccca gtagggctcc atgtcgctca
    14401 cgacgtccag gcccaggttg gtgtcgcgct cggtgttctc cagcgccgcc acgagcgcgg
    14461 agccggagac ctgggacgtg gtcccggcca tcgacgccgc cgcggcgtcg accgcgtcca
    14521 cgcccgcctc ggacgcggcg agcagggtgg ccagctgacc gcccgcggtg tcgtgggtgt
    14581 gcaggtgcag cgggaggtcg aagcgctcgc gcagcgccgt gacgagccgg cgtgccgcct
    14641 cggggcgcag cagacccgcc atgtccttga ttgcgagcac gtgggccccg gcgtccacgc
    14701 actgctgcgc gagatccagg tagtagtcca gcgtgtagac ggtctcgtcc gggtccagca
    14761 tgttgcccgt gtagcacagg gccacctcgg ccaccgcggt cccggtggcg cgcacggcct
    14821 cgatcgcggg gcgcatctgc tccacgtcgt tcagcgcgtc gaagatgcgg aagatgtcca
    14881 cacccgtctc cgcggcctcc gcgacgaacg cgttggtcac ctccacgggg tacggcgtgt
    14941 agcccacggt gttgcgcccg cgcagcagca tctggatggg gatgttgggc atggcctcgc
    15001 gcagcagccg cagccgctcc caggggtcct cccccaggaa gcgcagcgcg acgtcgtacg
    15061 tggcgccgcc ccaggcctcg accgagagca gacccggcag caggtgggcg taggccgggg
    15121 ccgccgcgag caggtcgcgg gtgcgcaccc gcgtggccag cagcgactgg tgggcgtcgc
    15181 ggaaggtcgt ggaggtcacc gcgagcggct cgtactcacg cagggcgcgg gcgaaaccct
    15241 cggggccctt ctcctgcagc acctggcgcc agcccgaggg gacctcgtgc ttcgagggcc
    15301 cgtcgaaggg gctgcggtag ggctcgtccc tcttgtcacc cgggtagtgc ggcaacttgt
    15361 cgcgcgggtc gatgccgtcc acgcgctcac cgttgggctt gttcaccgtg atctcggcca
    15421 ggtagttcag ggcgcgagta ccacggtccg ccgagccctt gcccttgagc aggtccgggt
    15481 ggttctcgat gaagtccgtg gccacgtcgc cgaccaggaa gtccgggttg tgcagcaccg
    15541 actgcaggaa ctggatgttg gtggcgatcc cgcggatgcg gaactccgcc agcgctcgcc
    15601 gggcgcgcag cacggcggtc tcgtagtcgc ggccacggca cgtgagcttc accagcatcg
    15661 agtcgaagtg cggagaaatc tcggcacccg cgtacagcgt gccgccgtcc aggcgcacgc
    15721 cggcgccgcc cgcggagcgg taggcggaga ccttgcccac gtccggccgg aagtcgttcg
    15781 cggggtcctc ggtggtgatg cggcactgca gcgccgcgcc gcgcacccgc aggccgtcct
    15841 ggctgatgcc caggtcctcg agcgtctccc ccgcggcgat ccgcagctgg gactgcacga
    15901 ggtccacgtc cgtgatctcc tcggtgacgg tgtgctccac ctggatgcgc gggttcatct
    15961 cgatgaacac gtgctggccc gcgcgctcac cggcggtgtc cacgaggaac tcgacggtcc
    16021 cggcgttcac gtagcccagc tccttggcga acttcacggc gtcgcggtgc agggcgtccc
    16081 ggatctcggg ttccagctgc ggggccgggg cgatctcgat aaccttctgg tggcgccgct
    16141 gcagggagca gtcgcgctcg aacaggtgca cgatgttgcc ctcgttgtcc gcgaggatct
    16201 ggacctcgat gtgccggggg cgcagcacgg cctgctcgat gaacaccgtg ggatcgccga
    16261 aggcggtgtc cgcctcgcgc atcgccgcgt ccagggcgcc gggcagctgc tcggggctct
    16321 ccacgcggcg catgccgcgc ccgccgccgc cggccacggc cttgacgaac acggggtagc
    16381 cgatcttctc ggcggccgcg atcagcgcgt ccttgtccga tgagggctcc gaggagtcca
    16441 gggtggggat cccggcacgc cgagcggcgc gcagcgcctc caccttgttc ccggcgagct
    16501 ccaggatctc ggcgcgcgga cccacgaacg tgatgccctc cgccgccgcg gcccgggcca
    16561 gctcggggtt ctcggagagg aacccgtagc ccgggtagat ggcatccgcc ccggattcct
    16621 tggccacgcg cacgatctcc gccacgtcca ggtacgcccg aaccgggtgg ccctcctcac
    16681 cgatgttgta ggcctcgtcg gccttctgcc ggtggatgga gttgcggtcc tcgtggggga
    16741 acaccgccac ggtccctgcg ccgagctcgt acgccgcgcg gaaggcgcgg atggcgatct
    16801 cgccacggtt ggccaccaag atcttggaaa acatgaggtc cgtttccgtg cacgtccgca
    16861 agggcgcgcg cactgggtga ggagttgata ccggctctca gcttacgtga gccagacctc
    16921 acgggagcgt gatccggtga tcgtgtcacg gcacgtctgt cctgtccccc gaagggcacc
    16981 cattagcatg taacggggcg gcggacagcc cccctttggg ttacagaagg gtcatccgtg
    17041 cagatcgtca gcatcagcag cctcaaaggc ggcgtgggca agtcctccgt ggtcctgggg
    17101 ctggcatccg ccgcgttgga cgccaggatc cccacgctgg tcgtggacct cgacccccac
    17161 ggggacgcct ccacggcact gggtgtgcac gcgcgcgcgg gccacgaggt gggcaccgtg
    17221 ctccgccggc cccgcaaggg cgctctcgcc tcggtggccg aggcctcgcc ctggaccacg
    17281 caccccatca ccccggacac ctccacggcc ggcccccgcg cctgggcgcc ggatgccgcc
    17341 cgcaccacgc gcgttcccgt gctcgacgtc gccccgggat ctgcggcgtc gtcgcacctg
    17401 gaccacgcgg cgtaccggcc gaaggacctg aaacggctgg agaccgctct gcgtgggctg
    17461 gaccgctacg aactcgtgct cgtcgactgc ccgcccaccc tcagcgcgct cacccgtatg
    17521 gcgtgggcgg cctcccacaa ggtcctctcg gtggccgagc cgtcgctgtt ctccgtggcc
    17581 gggacgaaac gcaccatgag cgccctggcg cagttcgagt cctcccgcat ctgggccgtg
    17641 cccgaggcag gggtcgtgat caacagggtg cgcaacgcct cccaggagca gcagcaccgg
    17701 ctgcgggaac tccgggacct gttcgggccg ctcgtggtgg accccgtgct gcccgacctc
    17761 ccggtggtgc agcaggctca gggggcggcg tggcccgtgc accgctggcc gggtgcggaa
    17821 gcggccgaga tcgccggacg cttcaccgcc gtgctggagg ggctcacgcg ctgaggcgat
    17881 gccctcccgg tcagccggcg ttcttcgtgc gacgccgtgc gcgacgcgcg gagagctcgt
    17941 cctcggggaa cggccccgcg gcctccgcgg caccctccag ggaggcatgc tctgcgggca
    18001 tggaggccag ggtggcctcc acctcgcgcc acacgcggcc cacggcgatg ccgaacacac
    18061 cctgcccgcc ctggacgagg tcgatgacct cgtgggggga ggtgcactcg tagacactcg
    18121 cgccgtctga catcagggtc agccgggtga ggtcctcgat gcccctgaga cgcagggcgc
    18181 ccacggcgga gcggatctgc tgcagggaga cgccggtgtc gagcagccgc ttgaccacct
    18241 tgaggacgag gatgtcccgg aagctgtaga gacgctgcga gccggatccc ttggcgccgc
    18301 gcaccgtggg ctccacgagg ctggtgcgcg cccagtagtc gagctgccgg tagctgatgc
    18361 cggcggcctt gcacgcggtg ggtccgcgga agcccacggt ctcgtcgagc gcggtgaggt
    18421 cgtccgagaa cagcatctcc tgcgttcccc cggccaggga ggatgcgcgc agctgcgccg
    18481 cgtcaagcgg caactcagga ttgctcaagc gtcctcctcg tgcgtggggc gggcagggga
    18541 cggcccacca tgctcccctg acggtaaacc cccggctgga acgggtcaaa gacatccggt
    18601 gcggttcagg tcgtgtcgcc gtgggtggcg caccccgtgt gcaccggggc ggtcaggact
    18661 ggaagtcgtc cgggtccacg tggtccagga agtcgcggaa ctccctcacc tgggcctccg
    18721 ctccccctgg cgactccacc gcctgctccc gcagctcgcc gtccgggctg agcaccagcc
    18781 ccgcctcgtc cagcacggcc gaggagcaca ggatggggca cccggtgcgc gccgcgaggg
    18841 cgagcgcgtc cgaggccctg gcatccacca cggtggcgtc gtcgaaggag atggccgcgt
    18901 ggaacaccgt gtcctccacg gtgtgcacca ccactcgggt gatgctgcgg cccagctccc
    18961 gcaccaccgc cagcagcagg tcgtgggtca gcgggcgagg gggctcgatc ccctgcaggg
    19021 cgaacacgat cgacgtggcc tcgttggtgc ccagccagat gggcagacga cggggcccgt
    19081 ccagttcacg cagcaccacc acgggctggc ccgtggggac gtccatgcgc acccccgcga
    19141 tctccatgcg gacgtccgcg ctcacgtgtc gctcccggag gagtccgggg tgtggaagga
    19201 acgcaccgtg tcgtccacct gggtggtgac caccgcggac atcacggaca ggcacaaggc
    19261 cgcgatctca cgggcgcgca gcacggccct gcgccgggtc tccggatcgc gtcgcgtgcg
    19321 cagcggcgcc acgctgccgt ccaccagtgc cacgacccgc tcggaggcac cccgcagcac
    19381 gcgcaggtgc cggggctcga tgccgtagcc gcggagcttc ccggcggcca ccgccacggc
    19441 cagggcgtgc tcgtcgtagg cgccggagcg ctccacgatc agcccgtggg tcagcagctc
    19501 gcgcagcagc gggacctccg ttccggatct cgcggcgagc tcgcgcaacg agtaccgggc
    19561 cgagctcggg cgaggcgggt ctccggcgtc ggcggcccct ggctccgcgg cgtccaccga
    19621 cacccgagga cgctgccgtt cggcaccggc ggcggggtcc tccccgcggt ccaggcgttc
    19681 cctgatgacc cgcagcggaa gatacctctc ctgctgcaga ctgagcaccg tggtgagacg
    19741 ctccacatcc tgctccgagt acttgcggta tccggacgcg gtgcggtgcg ggtgcacaag
    19801 accctggtcc tccaggaaac gcactttcga cgcggtcaga tccgggaagc gcggctgcag
    19861 ctgacgcagc agtgcgccga tgccgacacg ggcggtctgc gggagtccgg tctcaggcat
    19921 ggagggtgtc aggacccgtt ctgcacggag tggtagaacg tgaagcggaa cttgccgatc
    19981 tgcacctcgt caccgttctc gagcaccttg gtgttcacgc ggtcgctgtt gacgtacgtg
    20041 ccgttgagcg aggcctggtc cacgatctcg aaggtgttgt tgcggcggat gaactccgcg
    20101 tgccgccggg agacggtgac gtcgtccagg aacacggagc acgcggggtg gcgtccggcc
    20161 acgacctcgt cccggtccag caggaagcgc gcacccgtca gcccaccgtt ggtctcgagc
    20221 agcagagcag accccggggg aagcgaggcc acggcgttct gctcaccctc ggtgagtttg
    20281 tgctgcgcgg cggtggagag cacgtccgcg acgatctgga tggacgtggt ctccgggccc
    20341 gactgcgcgc ccgagttctc ttgattaggc atgggttccc ctcagctcac gtggaagttc
    20401 gagtctagtc cagcagctgc tggtaggcct gcgcgtccag caggtcggcc gtggcgtcct
    20461 gggactccac ccgcaccgtg aagagccagc cggcctcgta gggtgcgtcg ttgagcagcc
    20521 ccggggtgtc cgagagctcg tcgttgacgg agacgatctc accgctgacg ggagcgaaga
    20581 ggtcgctcac ggacttggtg gactcgatct cccccaccac gtcccccgcc gtgacggagt
    20641 ccccgacctc cggcagctgg acgaagacga cctcacccag ctcactctgg gcgtggtcgg
    20701 tgatgcccac cttgaaggtg ctgtcgtcgt tgaggtcctg gacccactcg tgctctgccg
    20761 tgtacgcgag ttccgcggga atgttggtca tgccggtcag tttagggcac atccgcggca
    20821 gtagcgcaca tcacacgcgt gcgtgtgcag tgcaaccgtt tcgccgtagc ccaacacgct
    20881 ccgtgcgcag cgccacgaat gggtgtccgg gggccgccac cggggtattt tggcccggtg
    20941 cccatcaccg aggcttttcg ccaggcggcg atccgcgtcc acacccacgg ctcccggatc
    21001 cgccggaccg tccccacaat gaggtcccgc cgggaccccc tgcacgtcca cgagctgacc
    21061 ccggggcgtt ccgcgcgtct gattctctcc gcgttcctgc tggcgctgct tacgggaacg
    21121 ggtctgctca tgctgccgct ggccacggtg gccccgggca gcacggacgt gatcacggcg
    21181 gccttcaccg ccacctcggc gctgtgcgtc acggggctga tcaccgtgga caccgccacg
    21241 tactggaccc cgttcggcca ggtggtgatc atctgtctca tccaggtggg tgggctcggc
    21301 gtcatgacgt tcaccaccat gctgggaatc ctgctgtccc gtcggctcgg tctctccgcc
    21361 cggctgctga ccagcgcgga gaccaagtcc ggtggcggag cgcgcctcgt ggtcgcacgc
    21421 atcgtgggga ccaccctggt catcgagggc accgcggcca ccatcctgtt cctgcggttc
    21481 ctgctgcact acgactactc cgtgggcacc gcactgtggc acggggtctt ccacgcggtg
    21541 tcagcgttca acaacgccgg tttcgcgctc tacaccctga acgtgatgga cttctcgggc
    21601 gacgccgtgg tgctgctcac cctgtcctcg tgcgtgatcc tgggcggcct gggtttcccg
    21661 gtcctcgccg agctgcggcg gcacatcagg attccgcacc ggtggagcat gaacacccgc
    21721 ctggtgctgt tcgccacccc gctgctgctc ctcagcggca ccgtgttcat cctggtgctc
    21781 gagtggagca acccggccac cctcgggtcg cagtcccccg ccgtcaaggt gctcaacgcg
    21841 ttcttccagt ccacgatctc ccgcaccgcg gggttcaaca gcatcgacat ctcccagatg
    21901 caccccgtgt cgtggctcgg catggacatc ctcatgttca tcggcggtgg ccctgcgggc
    21961 accgccggcg ggctcaaggt caccacgttc ggcgtgctgt tcttcatcgc gctcacggag
    22021 atccggggcg gtgccgccgt gccggtgctc ggcaagcagc tctcccgctc cgtgcagcgc
    22081 gaggcgatca cggtggtggt gctggccgcc ggggccgtca tcggagggtc catgctgctc
    22141 atgctcacgg accagtccct gggactggac cgggtgctgt tcgaggtggt ctccgcgttc
    22201 tccacggtgg gtctgagcac cgggatcacg cccgcactgg agccctttgc ccagtgcgtg
    22261 ctgatcgccc tgatggtcat gggccggctg ggtccggtca ccgtggccgc cgcgatcgcc
    22321 tacggtcgac gtccgccctc gttcggcctg cccaaggaac ggccgctcat cggctgatcc
    22381 acccgctccc gcgctgatcc ggcacgacgc cgcgcagcgc ttccccggca tcccgccgcc
    22441 gcaggacgcc ccaccccgga aggaagtccc atgttcggtt cccaactctc cgagatctcc
    22501 cgtcgaggca tgtccgacgc cgtggccgtg atcgggctgg gtcggttcgg gggtgccctc
    22561 gccctggagc tcatgcgcaa cgagaccgac gtgctgggca tcgaccacga ccaggccacc
    22621 gtgcagcgct tcaacggcaa gctgacctcg gtggtgcgcg cggacgccac ggacgaggac
    22681 gtgctgcgcg agctgtccgt ggacgagttc gagcgcgtgg tggtgggcat cggctccaac
    22741 atcgaggcga gcatcctcac cgcgtcccgg ctcgtgaagt tcgggtgccc gggcatctgg
    22801 gccaaggccc tcaccgagcc gcacgccgag atcctcacgc agctgggcgt gcagaacgtg
    22861 gtcaaccccg agagcgacat gggcacccgg gcagcgcacc tggtgcagca ccggatcctg
    22921 gacttcgtgc cgatcgacga cggccacgcg ctggtccgct gcaccccgcc ggaacccatc
    22981 cagcagcgcc ccatggacct gctgaacgtg aggcagcggc tcggggtctc ggtcgtggcc
    23041 gtgtgccgcc cgggcgggca gtgggagccc atcgaggccg ggaccatgct ctacgacgac
    23101 gaccagatcc tggtgacggg gcccacccgg aaggtggagc acttctccaa cctgacctga
    23161 ccgaccacgc ccccgatgtc cggatccacc cgcccctgag gcggcgatga acctgccgct
    23221 ccgggcccgg gcatcgccgc gggtctccca ggaccgtgcg cggcggggcc gcgggtctca
    23281 caggaaccgg gtgaggcggc gcagctcgcg tgcggtggcc ggagctgggg accggttgac
    23341 gatacccgtg agatccacgg gcacggcggc gtcgttctcc gggccgatgg ccacgaccac
    23401 cgagtgtggc gccgcgcccg ccggccgcgg tgcccgctcg accgtgacga accctgccac
    23461 ggagtgcgcc acgtagcggc gggctccgcg gaccgtggcc acgtccacca cggccttgac
    23521 gcggtagacc tcgtccgggg gatcctccag caggtccgcg agcgccgccg ggtccaccgt
    23581 ggcgggcacg tccaggctcg cggcgcggtg gtggacgtgg tgcgcgtgcc caccggcggt
    23641 gccgagctcc cacagcggta gctggccgcc ctcgggcacg gcacgctctg cggcatcgaa
    23701 gaacagtcgc gggtccacgg ctccccacgg tgcctcgagc accatggcgt ggggattggc
    23761 ctgcgcgacc cgctcgcgca cgcgcgcgga ctcgtggggc tccgccacgt ccgtcctggt
    23821 gagcagcacg agcgccgcgg ccttgacgtg ctgcgcgagg tcccagccac gctgctcggc
    23881 gtggggcacg tgggcggcgt cgacgacctc cacgagaccg ccgaagcgga cggagtccac
    23941 ggtgctgccc agcacgagct ggagcagcgc gggcggttcc gcgatccccg agccctcgat
    24001 gacgatggcg tcgaggtcca gtgccgggcg ggacagggtg cgcagggcgt cgtccagctg
    24061 cgcggggtcc tgcaggcagc acaggcagcc gcccgcgatc gacaggggtt ccgtcacgtg
    24121 gcccgccacg agaccggcgt ccacgttcac gtccccgaag tcgttgatca ccactcccac
    24181 acggcccccg cccgtggcca ggacgtggtt gagcacggtg gtcttgccgg cgcccaggta
    24241 gccggtgagg atcagcacgg ggacggtacg ggtcacgggg ctccttccac gcggtgcgat
    24301 gacgtggggg cgttgcgccg cgggcaccgc aggccaccgc caccacggac cgacggtgtt
    24361 ctgttcacgg ggccagcagt gtgccccggc cgagccgcag tacgcaagac gtcatccgcg
    24421 cgcggccgag ctgagccggt ccaccgcctc cacgatcgtg tccggggagc acgccaggtt
    24481 catgcgcgcg aaacccgctc ccccggcgcc gaacgtgggg cctgatgaca gcgccacctt
    24541 ggcgtgctcc gccgcgtgct cggcagggtc atccccccag tccaggtccc gcatgtcgag
    24601 ccaggccagg tacgtggcgc tgccccggcg gaaccggacc tgcggcagct tgtccgcgag
    24661 ctggcgctcg agcagcgcga tgttgctctc gatcacctcg atggtcgcgt ccaaccagtc
    24721 cgtggcgtgc cggaagccct cctgcgtggc cagcaggccc atgatccccg tccggtagga
    24781 cacggcgtcg ggcaccgtgg ccagccactg ggccatgggc tcggagtcca ccacgaacat
    24841 ggcggccttg agccccgcga ggttgaaggc cttgctcccg gaggccgccg cgacaccgtg
    24901 ccgacgggcg gcgtcggaca cggacaggta cggggtgaag gtggcgccgc ggtgcgtgag
    24961 cggtgcgtgg atctcgtcgc tcaccacgtg ggcgccgcgc cgctccacga tctcggcgag
    25021 ctccgtcagc tcctcgtggg cgtggaccag gcccagcggg ttgtgggggt tgcacagcag
    25081 caccgcgcgg gcgcccgcgg ccagcgcggc gtcgatgccg ggcaggtcca gacggtacgc
    25141 ggcgccgtcg tcctgcagcg ggacctccac cgggcggccc cccgcctccg cgaccaggtg
    25201 gtagaacggt gcgtacaccg gcggggtgag gaccacgccc tcgcctgggc ggatgagccg
    25261 gcgcagcgcc tcgacgatca ccacggtgac gtccgtggtg tacatgatgc gctcggggtc
    25321 tggccgccag ccccagcgtg cggccgcgaa gtccgcgtac gcctgcgccg caccgcggtc
    25381 cgccgtggcc gcgtatcccg tgtcgttgtt ctcgatcgcg gcctccagcg cggccttgac
    25441 cgggggcggc gtggggaagt ccatctccgc gatgaacatg ggcaggacgt cctcggggta
    25501 gctgcgccac ttggtgctcg tgcgtcggcg cagggagggc atctggtcgg cggtggtcat
    25561 ggggtccctt cgaacggtgc gcggccggga cgtcacgagc tggtgagctt gtgggcctgc
    25621 cccagccgca acaggtccag cgtcttctcc tgctcctcgg cgcgctcgca cagccgccgc
    25681 agcagatcac ggtccagcct gtcgtccgga gcctccagga gcattcgcca ccctagccgc
    25741 ttcgcgtgga cggcggccac gagtgcctcc agctcctcga tgtcggacag cggcgagcgc
    25801 ctgctgatcc gttcgttcgg cttcagccgc gcgagcctct cggccgcgcg cgcgggaagg
    25861 tccttgagcg ccgccggctg gacccccacc gaggccatga cctcttccag ggcgacctgg
    25921 tcctgcgcga tgtcctccgc catgcgaccc accgcctcgc gcacctcggc gtccccgtgg
    25981 aactcggcca cgcggcggaa cgcggccact cccgcggccg atcccgcgtg gtggtcctgc
    26041 aggtaggtgg tgatgacgct gctcatggtg cttcccttcc tcggtgtccc tccagccaag
    26101 cacgcggcac cgccacccca ccacccccgg gcgggtgcgg gtcggtcgga cgacgccgcg
    26161 cgtcacggcg ccgcggcagg cacccccgcg gcgtcgtccg gccgcgtcgt ccggaggtgg
    26221 tcaccggggc gctgcgtcat actgggggcg acgccgcgcg ggggacgtgg ccgcggcacc
    26281 gaggcttcac gatctggggg gatcatgaca ccggagactt tcatcgactt caccgcgccc
    26341 aacggcatgc ggtcctggta ccacgtgtgg cgcacgggca ccgcggggtt cctgtactac
    26401 ttcgacggcg actactggga cctggacgac acctcgatca actggcccga ggaaggggac
    26461 ctcgcccggc tcgccgtggc ggcgcaggcc cggaacctca tgctcgtggc cgtgaacacc
    26521 ccggacacgg acggccgcgg ggacgggtac acgtggtggg aggactgcaa gggcaacggc
    26581 aagttcttcc gtgcgctgca cgagcacctc gtggcgcggc actcggacgt ggactcctcg
    26641 accctctggc tgatcggcta cagcgggggc gcggagttca tcacctacga gctgctcgac
    26701 cgcggcatcg agggcatggc ccgtggcggg gccgtcatca tcgggggcgg cggagccgac
    26761 gcgccggtgg cccgcaagaa gaaggcccgc ccctgcatcg gctccaccgc catgcactgg
    26821 tgggtgggtg agct
//
