LOCUS       c00001_NZ_AZUI..       19619 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AZUI01000001.1 [Clostridium] indolis DSM 755
            K401DRAFT_scaffold00001.1_C, whole genome shotgun sequence.
ACCESSION   NZ_AZUI01000001
VERSION     NZ_AZUI01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:20:00
            Original ID  :: NZ_AZUI01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 56584
            Orig. end    :: 76203
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..285)
                     /locus_tag="ctg1_51"
                     /transl_table=11
                     /translation="MDFSFHVYVYPESLEKSLDINNVKEIQDGYCWKYIKEKIKEAMKE
                     KSGKILDREYKLFIRTSGDDFNSQLTANSTVKDYLRLAKFSPNIKCLYL"
     protocluster    1..19619
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[66219:66945]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9636..10361
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..19619
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19619
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(408..1781)
                     /locus_tag="ctg1_52"
                     /transl_table=11
                     /translation="MDKDSIKSRVRREIMMMLILGIGAWIVLLIFLSCKSLTGGEKDTY
                     EFLSDSEVLSLLSDKYDQEFQIINTFNLDELLKDSEIKLKVHGNALLHGYIWQLAPIND
                     REYTFFVMDYEAAGPPSPIPFSSGSKYSKAIDDFLVEKVKDDFQTVALENGLLFDEVKN
                     YMIDEERWEENYQLGILPFANPPIENIKFDIHVTDENKQEIADSFFPCLNGLAEQRYTY
                     SDKVERVNYIHITGNDGWEYVDLPYKGNELFDTKDKLIEFLKSITIDEKEYMERLPDPF
                     IDFMDRFELYSDVFKQIGADAKIETNSYGYTRLKLILSTGEIVYFDRKTNYEKISERRI
                     DKEKPYTDSDGTVLRATLRIQDSIYQSESTKENLCSVYLALYDGEKIKYGRGTPFELPY
                     FDKFMRDTVNHYSEEEVRDFDRYIKIFTAAEMEETYRRMQILKEQMLQEFDGRLQLIK"
     CDS             complement(1832..2965)
                     /locus_tag="ctg1_53"
                     /transl_table=11
                     /translation="MRNKWKKGLCLNFAVMMIFVFTTVFLCSCKNLYRETNKGVNSEAQ
                     KVLESVIEENGGVEPDMRYSTGEVSFNIHLGWKKVRDSECFWDRERTNVYGLNASSPLG
                     SFTPEECFSFLVEYYQEEDYFKLLDQSESLTQWYSEEKVLCYLGTITGEMEGGYTYTEV
                     VIAPQKNLVLTFVGQTSYIDIDKDTESTIKMNVTELRESLMFETGNADYVSGNTYLYDD
                     GSELCLHDDGTFAYYEKEEEHEKQYLAGTYETFYGQPAFDQVTSMEEYGLEKEELEQML
                     SANMNGYIPGGSRPIDYMYATNPDMTDTRPRYQICRDTFYAVVFHNMIYVNTEGEQEEI
                     EKDSLYIGFYIPELNIMDMTNCNAAAHATWAYKGKTE"
     CDS             complement(2955..3551)
                     /locus_tag="ctg1_54"
                     /transl_table=11
                     /translation="MERLDIDLYLACMEKEDKTESSEEKLKQKAMEKIEKLHQELQKIK
                     ELNMERTVFFGNLFSICLPKNLLLNEITEEDVILLRSQSEHMALVIKAVDCKKPIDLEH
                     VKKNYQEQMTMSKQQTWFDIDGSKVVDGVKIFYFTAIHSMPEQNQINYILLFCLDNKTV
                     ILDFNMREESYSFWKNSIAVMMKTIQKAGGDFDEK"
     CDS             complement(3629..4057)
                     /locus_tag="ctg1_55"
                     /transl_table=11
                     /translation="MLDYYKILGVLPQATEKDIKAAYRKLAKEYHPDVVQDDPDGNKKM
                     YEIQEAYGILGDAEKRKQYDSFRKEKKERGTAKREDSREQRERPGNAAPDMSQFERFFG
                     FQPGKGMETYRGTGDGAKKHDGPVNTNELFSAFFGVKK"
     PFAM_domain     complement(3863..4051)
                     /aSDomain="DnaJ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00226.33"
                     /description="DnaJ domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_55_0001"
                     /evalue="8.40E-24"
                     /label="ctg1_55"
                     /locus_tag="ctg1_55"
                     /protein_end="65"
                     /protein_start="2"
                     /score="83.6"
                     /tool="antismash"
                     /translation="DYYKILGVLPQATEKDIKAAYRKLAKEYHPDVVQDDPDGNKKMYE
                     IQEAYGILGDAEKRKQYD"
     CDS             complement(4109..4534)
                     /locus_tag="ctg1_56"
                     /transl_table=11
                     /translation="MGFTLKVEGPSTIDLGTISITGVKFKTDIPLDSNARSTDLGSTVE
                     ISGKILTAVDGDPFDSTRQLGLWSLVPAEKSDCYRKVTVEVIAASQVVRKYTYPNAFVV
                     DYKENYGDTEGVGTFRLIIKQKKDKMAQIAVEGGYSV"
     CDS             complement(4568..4996)
                     /locus_tag="ctg1_57"
                     /transl_table=11
                     /translation="MGLRMKITGSETVQLRETSITNVVFGADIPHDSNARSTDLGSTVL
                     IEGKILAAVGGEAADDTSKLARWSLVPAENSDCYRNVQIDVVNASQVVRQITVPNAFVV
                     DYREDFTDETGTGVFKLLIKQKKDKMASLKFEGGFSGE"
     CDS             complement(5089..5181)
                     /locus_tag="ctg1_58"
                     /transl_table=11
                     /translation="MYGNVSTIVTIIFFVIAGYTIYKGIRKKYK"
     CDS             complement(5232..7400)
                     /locus_tag="ctg1_59"
                     /transl_table=11
                     /translation="METITQTNRTILFSEMNPEKLNLLTLIGDVRGKTSLDDDKIKEIN
                     ETLLVESFEDFLEKFAPVVYSWCDANTGSIQYSLIKPENIPDNCITEIPLNEMNDLLNM
                     LITLQDARGSLGVANVDFKFSNVLEMISPKKIMEDIRQVRREIQYTYGNYMGLEEEDPK
                     RLDLGDKLNYQFEQASHNYNNVLAMLPLAIEDIKTRLLLGNGETAQRGQEFKAGLLSMG
                     DDGELKILEMKQEEGTQLAIVDDHINTSLIQTFRDDYDALNENKSDYVRELVVRTFCPL
                     SSTMESSVDREVEVQNYNTYLEFYKKSKDDFIRAVKPLIEKILGVKAYFDQYKVKEKGM
                     QPRLLITNTPLEMMIKSSNLPRLLTYLNTTNDKNEFENTLWFGIVPDVELNQTGDGKLQ
                     RMRFAGNQKVKKPGTNTMENLAILMNAINPYKITTFFSFATGEESTFNYVATEGIGIFK
                     DKCAPLMKRDYSEFVVPCIPNVTIIPKDKSGLILDKRMVIDDNGNVTLSQEKEDIMKMW
                     IEGVYVGAAYGAAGIAAAWQCPEYLKQRFPNTTMEYPGVRYDIEAGDNALLVTTSMTKE
                     ISGFTNAIKNSINNTGFGFVFTSDNAQHKGREIKNVMVYKARNLLSNGTEFEPIYKTLL
                     VTYIERMLRFYSGDFKQDKILQFFSNNPSSQKSKWDANRQYVNSLLQDGDELDFSIDEK
                     NGICNIQLTFSNTTRNLKVELTRKGQTA"
     CDS             complement(7507..9528)
                     /locus_tag="ctg1_60"
                     /transl_table=11
                     /translation="MKRFKTVSFLLSCLFFISISFCSSGEEIASGKNGLDVMFVMDYSG
                     SMSANDPDHTAIGMVKAFIDTVHSADIRIGFVAYNDHIVSSAAPVSVRTQEERDALKAL
                     MDSAGYSGNTDIGLGLNYAYGLTGQENGRKCMIVLISDGETDLKGSRAGRTREISDQDL
                     RNTVEACRSRNIPLYTVAFGKYDGSKEILKEISSQTGGQNYTVEKPETLIEVLYGIFHD
                     NMAYRIQEIAGGIYGEGSQSLRIKLDDSHLDEMDVLMISPQQIGDTTVVYGEQQIKPVN
                     LVHYSVAKVSDIKKDISEMNIQTNTRKNQELKIYLISYRDLTPVMEIETAIARNKPLSY
                     KIYFKDKSGSVIKDEAFYANFTPKVVIYPDGQSDSDRRDVETTVKEGILAGEMVLTQSG
                     TYYIEARLDDRMESCIFNTVRIQVINTPPTGELPKNIHYNPLSREKQLVLNNYFIDSDG
                     DGIFYTLEQDAGDLAEVGLNNGILTIKPVKAGSRNLILKISDGEAAISYTYSLEIIPLW
                     KAYWWVIVLVLAAAGAVIWRLFHKPKPELEVITEKKAQNRFQGKMDAYFMEQPEEEEEI
                     PPLTFPMYKIKDNRVSLGDLMKEYPGASESLGLDHIFLIADEDRRMILYHSSESSLMIG
                     SSIMCKKIQYSVSFGDIISITSPDGAYDLEIHYISMIQ"
     PFAM_domain     complement(8890..9423)
                     /aSDomain="VWA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00092.30"
                     /description="von Willebrand factor type A domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_60_0002"
                     /evalue="3.70E-19"
                     /label="ctg1_60"
                     /locus_tag="ctg1_60"
                     /protein_end="213"
                     /protein_start="35"
                     /score="69.7"
                     /tool="antismash"
                     /translation="DVMFVMDYSGSMSANDPDHTAIGMVKAFIDTVHSADIRIGFVAYN
                     DHIVSSAAPVSVRTQEERDALKALMDSAGYSGNTDIGLGLNYAYGLTGQENGRKCMIVL
                     ISDGETDLKGSRAGRTREISDQDLRNTVEACRSRNIPLYTVAFGKYDGSKEILKEISSQ
                     TGGQNYTVEKPETLI"
     CDS             complement(9636..10208)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_61"
                     /sec_met_domain="AgrB (E-value: 4.5e-27, bitscore: 93.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKRFELMLARYAYKRDSLSSVSFETYEYAAQVTLEMLMGVLANIA
                     IALCLNMKLEAVVFFLVFCVLRSYAGGLHLDKFSHCFLFSFAVTTGSMLLVKYMNVSLA
                     VSGIMMGGGLIAFWLTKPVNDKNRDVNEEEDAYFKSKLRQSLSIITIAYFTTALLSFLR
                     YSFLIALTVDVVYILMILGKWKNKSTV"
     PFAM_domain     complement(9669..10145)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_61_0003"
                     /evalue="2.00E-26"
                     /label="ctg1_61"
                     /locus_tag="ctg1_61"
                     /protein_end="180"
                     /protein_start="21"
                     /score="92.6"
                     /tool="antismash"
                     /translation="SFETYEYAAQVTLEMLMGVLANIAIALCLNMKLEAVVFFLVFCVL
                     RSYAGGLHLDKFSHCFLFSFAVTTGSMLLVKYMNVSLAVSGIMMGGGLIAFWLTKPVND
                     KNRDVNEEEDAYFKSKLRQSLSIITIAYFTTALLSFLRYSFLIALTVDVVYILMI"
     CDS             complement(10212..10361)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_62"
                     /sec_met_domain="TIGR04223 (E-value: 1.2e-05, bitscore:
                     23.7, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFMKKLKRNHSVFNFLILSVILYSANARCCWISHQPKMTEDVRK
                     FKRF"
     aSDomain        complement(10227..10322)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_62_0001"
                     /evalue="9.20E-06"
                     /identifier="TIGR04223"
                     /label="ctg1_62"
                     /locus_tag="ctg1_62"
                     /protein_end="45"
                     /protein_start="13"
                     /score="23.7"
                     /tool="antismash"
                     /translation="FNFLILSVILYSANARCCWISHQPKMTEDVRK"
     CDS             complement(10590..11891)
                     /locus_tag="ctg1_63"
                     /transl_table=11
                     /translation="MNAVKMIFTSISMSLYSTLLLKVYLDIFLAKKSRYAGVAGWALFF
                     LWQFCINMELIYFHPVINLILTLTTVLSVGIISYEGILWKRFTFPITFVMMWMLLEGIG
                     DAGYLFLNNGQNPSFMINSIFAKFLLFLIVMGIRWFMNRHGGGMVPYGGGAYLTIFLLS
                     GLILYPVFYMLVETSDRKVTDSFGWLLMAALILTIMNLSIYPIYLRLVETIQVKRNAHM
                     YVKQLEYYGRQHDLEEAASAEIQEMKHDMKQRLIYLQELVKSDQKEKLLTTLENLIGQS
                     VSIGRLESKTGNLIIDAMVNHIWEKTSKKEIRLHTKLEVPGVMKIKDEDLGVLLGNAFD
                     NAVEASEYVEKDKREIWIEITHEKGYLYIFVRNRYQGKIEHDKEHRLVSRKEESFHGWG
                     IYSMKKIAKRYHGQVKLDWEGDIFSLETILYDDI"
     PFAM_domain     complement(10605..10916)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_63_0004"
                     /evalue="3.70E-20"
                     /label="ctg1_63"
                     /locus_tag="ctg1_63"
                     /protein_end="429"
                     /protein_start="325"
                     /score="71.8"
                     /tool="antismash"
                     /translation="IKDEDLGVLLGNAFDNAVEASEYVEKDKREIWIEITHEKGYLYIF
                     VRNRYQGKIEHDKEHRLVSRKEESFHGWGIYSMKKIAKRYHGQVKLDWEGDIFSLETIL
                     "
     CDS             complement(11895..12548)
                     /locus_tag="ctg1_64"
                     /transl_table=11
                     /translation="LLELGKNAGIQVEVECYEDGSDLVQAVIEGRRFDIIYLDVRMKYM
                     NGLEAAYKIREIDRTVQMVYVTSHDGYMKDAFRVAPIGFLTKPIKKNEFEETFYYVLRI
                     VEEQDSYYRFQYKKSDYKVLIRDILYFESKLRVAEIALQDGLLKEYKALNKIEKNLENS
                     KGKFLRIHKSYLVNYQHVIRMGYEEVEMPKGIILPLSRAYKKAVDDKLRQYKKR"
     PFAM_domain     complement(11916..12188)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_64_0006"
                     /evalue="2.70E-12"
                     /label="ctg1_64"
                     /locus_tag="ctg1_64"
                     /protein_end="211"
                     /protein_start="120"
                     /score="46.9"
                     /tool="antismash"
                     /translation="YKVLIRDILYFESKLRVAEIALQDGLLKEYKALNKIEKNLENSKG
                     KFLRIHKSYLVNYQHVIRMGYEEVEMPKGIILPLSRAYKKAVDDKL"
     PFAM_domain     complement(12261..12512)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_64_0005"
                     /evalue="1.10E-12"
                     /label="ctg1_64"
                     /locus_tag="ctg1_64"
                     /protein_end="96"
                     /protein_start="12"
                     /score="48.2"
                     /tool="antismash"
                     /translation="EVECYEDGSDLVQAVIEGRRFDIIYLDVRMKYMNGLEAAYKIREI
                     DRTVQMVYVTSHDGYMKDAFRVAPIGFLTKPIKKNEFEE"
     CDS             complement(13021..13863)
                     /gene_functions="transport (smcogs) SMCOG1069:putative ABC
                     transporter permease protein (Score: 266; E-value:
                     5.8e-81)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_65"
                     /transl_table=11
                     /translation="MTAASKKQMWRLFKFVVLTAFLVLTMFPFLWMLLTSLKGSQGEIY
                     AFPVKYLPDPVSLVNYAAMLWKGNFARYLCNSFFTSSVAAACSVFISILASYVISRFRF
                     RFKNVLLLFFLVTQMIPMFIMLAPLYQMLGKMRMLNNLYGLAMLYTNMMIPFSVVTLCG
                     FFDGVPKSLEEAAWIDGCGYLQALFQVIVPVIMPGIAATFIFAFINSWNELFMSVMFID
                     VDKFKTIPVGLNALILKYDIKWGEMAAGTIMSLIPTMCLFTFAQKYMIEGLTAGSVKG"
     PFAM_domain     complement(13084..13596)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_65_0007"
                     /evalue="7.00E-16"
                     /label="ctg1_65"
                     /locus_tag="ctg1_65"
                     /protein_end="260"
                     /protein_start="89"
                     /score="58.6"
                     /tool="antismash"
                     /translation="FISILASYVISRFRFRFKNVLLLFFLVTQMIPMFIMLAPLYQMLG
                     KMRMLNNLYGLAMLYTNMMIPFSVVTLCGFFDGVPKSLEEAAWIDGCGYLQALFQVIVP
                     VIMPGIAATFIFAFINSWNELFMSVMFIDVDKFKTIPVGLNALILKYDIKWGEMAAGTI
                     MSLIPTMC"
     CDS             complement(13867..14772)
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 258.1; E-value:
                     1.6e-78)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_66"
                     /transl_table=11
                     /translation="MKQKSRLQLKRACFIFLMVLPAVIIPIIFTYYPMIRGSMMAFQSY
                     NLMNIKNIKWVGFDNFKKLFEHSASNTFYSTMWNTVKWVGISLFFQFVTGFAMALLLKK
                     KFKGSGVYQGLIFFPWAVSGFIIGIMWRWMFNGTSGVINDLLMKLHLIRLPVGWLASKN
                     TALYSCIIANIWYGIPFFTIMITAALRGVPEELYEAADVDGANPFQKFSAITVPCIRSV
                     LLLTVLLRVIWIFNFPDLIYSMTQGGPAGSSNIITSYMMQLVQSLDYGMASAVGVLCIL
                     FLMIFASFYLTLTKYTDKEA"
     PFAM_domain     complement(13885..14499)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_66_0008"
                     /evalue="1.80E-20"
                     /label="ctg1_66"
                     /locus_tag="ctg1_66"
                     /protein_end="296"
                     /protein_start="91"
                     /score="73.6"
                     /tool="antismash"
                     /translation="FVTGFAMALLLKKKFKGSGVYQGLIFFPWAVSGFIIGIMWRWMFN
                     GTSGVINDLLMKLHLIRLPVGWLASKNTALYSCIIANIWYGIPFFTIMITAALRGVPEE
                     LYEAADVDGANPFQKFSAITVPCIRSVLLLTVLLRVIWIFNFPDLIYSMTQGGPAGSSN
                     IITSYMMQLVQSLDYGMASAVGVLCILFLMIFASFYLTLTKY"
     CDS             complement(14889..16268)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 184; E-value:
                     9.3e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_67"
                     /transl_table=11
                     /translation="MRKKRAAALALAVAAVLSGCSGNTATEATTSASGETAKTESTKED
                     SGKTGETVTISLVESLTSPERTVILREIADKYETEHPNVKIDIVSPPLENADAKITQML
                     MNGSGVDIVEVRDSTITQFVTNEWIADLQKYLDSWSEKDTLTDSAKEVIHYMKDGAYMV
                     PYGFYQRGLYYRADWFKEKGLKQPETWQDIYDSGVAITDPASSRFGYSFRGGTSGYQYA
                     DTIYWSWIGTDKLADSNAGYFLKDGNGATIFTLPEVKEALHFYKDLFKNASPTDSIAWG
                     FSEMVQGFVGGTTSMLIQDPEVIATCSADLQDDQWDLVPFPKGPSGQAVFPNGFAGWGM
                     TSFTEHPDEAADFLLYLSNSENNTYFAKNYSTIPIHSNAAEKDSYFSEARFAMYMDMAK
                     EPEVYRHAAYPQMYEAFATYKTEVDTMYQKYLTDEITDDDLLKWLDEFWTKAYQDEGQK
                     W"
     PFAM_domain     complement(15180..16067)
                     /aSDomain="SBP_bac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01547.27"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_67_0009"
                     /evalue="2.00E-30"
                     /label="ctg1_67"
                     /locus_tag="ctg1_67"
                     /protein_end="363"
                     /protein_start="67"
                     /score="106.9"
                     /tool="antismash"
                     /translation="VILREIADKYETEHPNVKIDIVSPPLENADAKITQMLMNGSGVDI
                     VEVRDSTITQFVTNEWIADLQKYLDSWSEKDTLTDSAKEVIHYMKDGAYMVPYGFYQRG
                     LYYRADWFKEKGLKQPETWQDIYDSGVAITDPASSRFGYSFRGGTSGYQYADTIYWSWI
                     GTDKLADSNAGYFLKDGNGATIFTLPEVKEALHFYKDLFKNASPTDSIAWGFSEMVQGF
                     VGGTTSMLIQDPEVIATCSADLQDDQWDLVPFPKGPSGQAVFPNGFAGWGMTSFTEHPD
                     EAADFLLYLSNSENN"
     CDS             complement(16296..17480)
                     /NRPS_PKS="Domain: Beta_elim_lyase (63-285). E-value:
                     1.8e-08. Score: 25.8. Matches aSDomain:
                     nrpspksdomains_ctg1_68_Beta_elim_lyase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168:O-succinylhomoserine sulfhydrylase (Score: 357;
                     E-value: 1.7e-108)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_68"
                     /transl_table=11
                     /translation="MSDQSRYLKSDKLITAHYGEEYEHYYNAVVPPIFMNSLNVFETID
                     EYYDFDRTDKHKYCYGRVQNPTVRILEDKIAALEHGAGALAFASGMAAATTAVLTVCKT
                     GSHVICIHNSYGPLRDFLTGYCKEHMDISTTFVKGDCLEEFEENITDKTDLIVLESPSS
                     LVFSLQDIEAVSNIAKKHQALVYIDNTFCTPIYQQPLTLGADIVMHTTSKYIGGHSDII
                     GGMLAVKDPGLMKKLTANRELLGGIAGPMEAWLMIRGLRTMAVRIAQHQETAMAVARFL
                     ETHPKVKNVYYPGLESHPQYLLMKKQQSGNTGLLSFEIHGTLKDAEKLAESLRIFKIGV
                     SWGGFESLAFLPHARMEEDRCKVLGGSQKIIRIHCGLEGTEALISDLESALAQI"
     PFAM_domain     complement(16308..17438)
                     /aSDomain="Cys_Met_Meta_PP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01053.22"
                     /description="Cys/Met metabolism PLP-dependent enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_68_0010"
                     /evalue="9.40E-118"
                     /label="ctg1_68"
                     /locus_tag="ctg1_68"
                     /protein_end="391"
                     /protein_start="14"
                     /score="393.2"
                     /tool="antismash"
                     /translation="TAHYGEEYEHYYNAVVPPIFMNSLNVFETIDEYYDFDRTDKHKYC
                     YGRVQNPTVRILEDKIAALEHGAGALAFASGMAAATTAVLTVCKTGSHVICIHNSYGPL
                     RDFLTGYCKEHMDISTTFVKGDCLEEFEENITDKTDLIVLESPSSLVFSLQDIEAVSNI
                     AKKHQALVYIDNTFCTPIYQQPLTLGADIVMHTTSKYIGGHSDIIGGMLAVKDPGLMKK
                     LTANRELLGGIAGPMEAWLMIRGLRTMAVRIAQHQETAMAVARFLETHPKVKNVYYPGL
                     ESHPQYLLMKKQQSGNTGLLSFEIHGTLKDAEKLAESLRIFKIGVSWGGFESLAFLPHA
                     RMEEDRCKVLGGSQKIIRIHCGLEGTEALISDLESAL"
     aSDomain        complement(16626..17291)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_68_Beta_elim_lyase.1"
                     /evalue="1.80E-08"
                     /label="ctg1_68_Beta_elim_lyase.1"
                     /locus_tag="ctg1_68"
                     /protein_end="285"
                     /protein_start="63"
                     /score="25.8"
                     /tool="antismash"
                     /translation="QNPTVRILEDKIAALEHGAGALAFASGMAAATTAVLTVCKTGSHV
                     ICIHNSYGPLRDFLTGYCKEHMDISTTFVKGDCLEEFEENITDKTDLIVLESPSSLVFS
                     LQDIEAVSNIAKKHQALVYIDNTFCTPIYQQPLTLGADIVMHTTSKYIGGHSDIIGGML
                     AVKDPGLMKKLTANRELLGGIAGPMEAWLMIRGLRTMAVRIAQHQETAMAVARFLETHP
                     "
     CDS             complement(17579..18262)
                     /gene_functions="regulatory (smcogs) SMCOG1071:GntR family
                     transcriptional regulator (Score: 122; E-value: 5.2e-37)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_69"
                     /transl_table=11
                     /translation="MANKIQRTSLQLEIIRYIQNYIEENDLKAGDRLPSQEQLLEMMGV
                     SRTSLREAMKTLEARNVLEVRNGKGVYVGSQKDSAFLSLIDFTKEKGKLLEALEVRKIL
                     EREILRMVIHTVTEEELKELGDITKVLMEKYHQGVRQTEEDKLFHYTIYRLSHNDIMYQ
                     LILSISHVMDQFWEFPLNMEDPFLESLPLHEKLYEAIRGKNVKKAQIINEQLLDAVYRD
                     IKKQI"
     PFAM_domain     complement(17615..17974)
                     /aSDomain="FCD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07729.14"
                     /description="FCD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_69_0012"
                     /evalue="4.10E-16"
                     /label="ctg1_69"
                     /locus_tag="ctg1_69"
                     /protein_end="216"
                     /protein_start="96"
                     /score="59.6"
                     /tool="antismash"
                     /translation="ALEVRKILEREILRMVIHTVTEEELKELGDITKVLMEKYHQGVRQ
                     TEEDKLFHYTIYRLSHNDIMYQLILSISHVMDQFWEFPLNMEDPFLESLPLHEKLYEAI
                     RGKNVKKAQIINEQLL"
     PFAM_domain     complement(18044..18232)
                     /aSDomain="GntR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00392.23"
                     /description="Bacterial regulatory proteins, gntR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_69_0011"
                     /evalue="1.00E-17"
                     /label="ctg1_69"
                     /locus_tag="ctg1_69"
                     /protein_end="73"
                     /protein_start="10"
                     /score="63.6"
                     /tool="antismash"
                     /translation="QLEIIRYIQNYIEENDLKAGDRLPSQEQLLEMMGVSRTSLREAMK
                     TLEARNVLEVRNGKGVYV"
     CDS             complement(18768..19619)
                     /locus_tag="ctg1_70"
                     /transl_table=11
                     /translation="MPLVTTSQILSDARNGRYAVGAFNVENMEMVMAVIQAAEELNAPV
                     ILQTTPSTVKYAGLDLYLANVKTAAERAKVPVVLHLDHGSDFRLAMQALRTGYTSIMID
                     GSHEAFEANIELSRRVVEACMPSNIPVEAELGKVGGKEDDLDGGEGSAYTDPEEAKTFV
                     EKTGVNSLAVAIGTAHGIYKGEPKLDLERLSEIARAVAIPLVLHGASGVPDETVKMAIE
                     RGICKVNYATELRIAYSEGVKEVLKENPDTIDPKKYGSAGISKVKRFVKEKMTTCGCAG
                     KG"
     PFAM_domain     complement(18774..19610)
                     /aSDomain="F_bP_aldolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01116.22"
                     /description="Fructose-bisphosphate aldolase class-II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_70_0013"
                     /evalue="5.20E-103"
                     /label="ctg1_70"
                     /locus_tag="ctg1_70"
                     /protein_end="282"
                     /protein_start="3"
                     /score="344.4"
                     /tool="antismash"
                     /translation="VTTSQILSDARNGRYAVGAFNVENMEMVMAVIQAAEELNAPVILQ
                     TTPSTVKYAGLDLYLANVKTAAERAKVPVVLHLDHGSDFRLAMQALRTGYTSIMIDGSH
                     EAFEANIELSRRVVEACMPSNIPVEAELGKVGGKEDDLDGGEGSAYTDPEEAKTFVEKT
                     GVNSLAVAIGTAHGIYKGEPKLDLERLSEIARAVAIPLVLHGASGVPDETVKMAIERGI
                     CKVNYATELRIAYSEGVKEVLKENPDTIDPKKYGSAGISKVKRFVKEKMTTCGCAGK"
     aSDomain        complement(18774..19613)
                     /aSDomain="TIGR01859"
                     /aSTool="tigrfam"
                     /description="fruc_bis_ald_: fructose-1,6-bisphosphate
                     aldolase, class II"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_70_0002"
                     /evalue="4.70E-104"
                     /identifier="TIGR01859"
                     /label="ctg1_70"
                     /locus_tag="ctg1_70"
                     /protein_end="282"
                     /protein_start="2"
                     /score="346.0"
                     /tool="antismash"
                     /translation="LVTTSQILSDARNGRYAVGAFNVENMEMVMAVIQAAEELNAPVIL
                     QTTPSTVKYAGLDLYLANVKTAAERAKVPVVLHLDHGSDFRLAMQALRTGYTSIMIDGS
                     HEAFEANIELSRRVVEACMPSNIPVEAELGKVGGKEDDLDGGEGSAYTDPEEAKTFVEK
                     TGVNSLAVAIGTAHGIYKGEPKLDLERLSEIARAVAIPLVLHGASGVPDETVKMAIERG
                     ICKVNYATELRIAYSEGVKEVLKENPDTIDPKKYGSAGISKVKRFVKEKMTTCGCAGK"
     aSDomain        complement(18774..19619)
                     /aSDomain="TIGR00167"
                     /aSTool="tigrfam"
                     /description="cbbA: ketose-bisphosphate aldolase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_70_0003"
                     /evalue="8.90E-98"
                     /identifier="TIGR00167"
                     /label="ctg1_70"
                     /locus_tag="ctg1_70"
                     /protein_end="282"
                     /protein_start="0"
                     /score="325.2"
                     /tool="antismash"
                     /translation="MPLVTTSQILSDARNGRYAVGAFNVENMEMVMAVIQAAEELNAPV
                     ILQTTPSTVKYAGLDLYLANVKTAAERAKVPVVLHLDHGSDFRLAMQALRTGYTSIMID
                     GSHEAFEANIELSRRVVEACMPSNIPVEAELGKVGGKEDDLDGGEGSAYTDPEEAKTFV
                     EKTGVNSLAVAIGTAHGIYKGEPKLDLERLSEIARAVAIPLVLHGASGVPDETVKMAIE
                     RGICKVNYATELRIAYSEGVKEVLKENPDTIDPKKYGSAGISKVKRFVKEKMTTCGCAG
                     K"
ORIGIN
        1 ttacaaatat aaacatttaa tattgggact aaatttagca agtctaagat aatcttttac
       61 agttgaattt gctgttagtt gactattaaa atcatctccg ctcgttctga taaataattt
      121 atactctcta tctaatattt ttcccgattt ttccttcatt gcctctttaa ttttttcttt
      181 tatatacttc caacaataac catcctgaat ctctttcaca ttgttaatat ccagactttt
      241 ttccaatgat tcaggataaa catatacatg aaaactaaaa tccatatcac tttctgttcc
      301 ccatcctact catggaaatg gtgatccgga accagttcca taccaatact gttctaaaat
      361 aaattctccg tttttattat ctttcacttt ttacttctgc ctgccctcta cttaataagt
      421 tgaaggcgac catcaaattc ctgaagcatt tgctctttta aaatctgcat tcgtctataa
      481 gtctcttcca tttctgcagc agtgaatatt tttatatacc tatcaaaatc tcgtacctct
      541 tcttcactat aatgatttac cgtatccctc ataaacttat caaaatatgg cagttcaaac
      601 ggtgtaccac gcccgtattt aatcttttca ccatcataca aagctaaata taccgagcag
      661 agattttctt tggtactttc cgattgataa atgctatcct gaattcttag agttgcccgc
      721 aatactgttc catctgaatc tgtatatggt ttctctttgt ctattctacg ctccgatatc
      781 ttttcataat tggtctttct atcaaaatat acaatttctc ccgttgaaag tatcagtttt
      841 aaacgtgtat aaccataact gtttgtttca atttttgcat cagctcctat ttgtttaaaa
      901 acatcgctat acaattcaaa acggtccata aaatcaataa acggatctgg taatcgttcc
      961 atatattcct tttcatctat cgttatagat tttaaaaatt caattagttt atcttttgta
     1021 tcaaaaagtt cattcccttt gtacggtaaa tctacatatt cccatccatc gttaccagta
     1081 atatgaatat aatttactct ttcgacttta tcgctataag tatatcgttg ctctgccaaa
     1141 ccatttaaac acggaaaaaa gctatcggca atttcctgct tattttcatc cgtcacatga
     1201 atatcaaact taatattttc tataggcgga ttagcaaatg gcaggattcc taactgataa
     1261 ttttcttccc atctttcttc atcaatcata taattcttaa cttcatcaaa gagcaatcca
     1321 ttttctaagg caacagtttg aaaatcatct tttacctttt ctacaagaaa atcatcaatg
     1381 gctttagaat attttgaacc agaagaaaaa ggaatcggtg atggaggtcc agctgcttcg
     1441 taatccatca caaaaaaagt gtattcacga tcattaattg gtgcgagctg ccatatataa
     1501 ccatgcagca aagcgtttcc atgtactttc agttttattt cactatcttt taataattca
     1561 tctaaattaa aagtattaat aatctgaaat tcttgatcat atttatcgga aagaagagat
     1621 aagacctcag aatctgacaa aaattcataa gtgtctttct ctccgccagt taatgattta
     1681 cagcttaaaa agatcaaaag aacaatccat gcaccaattc ccaaaatcaa catcatcatt
     1741 atttcacgtc tcactctgct tttgatggaa tccttatcca tcccacacct tcttcccctc
     1801 ccattattat ctgcctaagc gttccctacc atcattccgt tttcccttta taagcccacg
     1861 ttgcatgagc agccgcattg cagtttgtca tatccataat attcaattca ggaatgtaaa
     1921 atcctatata aagagaatcc ttctcaattt cctcttgctc tccttctgta ttgacatata
     1981 tcatattatg aaaaacaacc gcataaaatg tatccctgca tatctggtac cgaggccgtg
     2041 tatcggtcat atccgggttt gtcgcataca tataatctat gggcctgctt cccccaggta
     2101 tatatccgtt catatttgca gacagcattt gctccagttc ctctttctca agaccatatt
     2161 cttccatgga tgtcacttga tcaaatgccg gctgaccgta aaaagtttca tatgttcctg
     2221 ccagatattg cttttcatgt tcttcttcct tttcgtaata ggcaaatgtc ccgtcgtcat
     2281 gcaggcatag ctcagaaccg tcgtcatata aatatgtatt accgcttaca taatcagcat
     2341 ttcccgtttc aaacataagg ctttccctta attctgttac attcatttta atagtcgatt
     2401 ccgtatcctt atctatatca atataagaag tctgccccac aaaagtaaga acaagatttt
     2461 tttgcggcgc aataacaacc tccgtataag tatatccacc ttccatctcc ccagtaatcg
     2521 ttcctaagta gcagagtact ttttcttcgg aataccattg tgtcagagat tcactttgat
     2581 ccaacaattt aaaataatct tcctcctgat aatattcgac caaaaaggaa aaacactcct
     2641 ctggtgtaaa agaaccaagc ggagaactgg cattcaagcc ataaacattg gtacgttctc
     2701 tatcccaaaa gcattcagaa tcccgaactt tcttccaacc aaggtgaata ttaaaagaca
     2761 cttctcctgt cgaatatctc atatccggct caacaccgcc attttcttca ataaccgatt
     2821 ccaggacttt ttgcgcttct gagttcacac ccttattggt ttctctatac aaattcttac
     2881 aggaacataa aaaaactgtt gtaaatacaa aaatcatcat cacagcaaaa ttcagacaca
     2941 gccctttttt ccacttattt ctcatcaaaa tcccctcctg ccttttgtat cgttttcatc
     3001 atcacagcaa tgctgttttt ccaaaatgag taactttctt ccctcatatt aaaatcaagg
     3061 ataacggttt tattatccag gcagaataaa aggatatagt ttatctgatt ttgttccggc
     3121 atagaatgaa ttgcagtaaa ataaaaaatt ttcactccat ccaccacttt acttccatct
     3181 atatcaaacc atgtttgctg ttttgacata gtcatctgtt cctgataatt ctttttcaca
     3241 tgttctaaat caatcggctt cttacagtcc acagccttaa tcaccaatgc catatgttca
     3301 gactgagaac gcaataatat aacatcttct tccgtaattt catttaggag aagattcttg
     3361 ggaaggcaga tagaaaataa atttccaaag aatactgtcc gctccatgtt cagttctttt
     3421 atcttctgga gttcctgatg gagcttttct attttttcca ttgctttttg tttcagtttt
     3481 tcttcactgc tttctgtttt atcttctttc tccatacagg ctaaatataa atcaatgtcc
     3541 agccgttcca tctgcttttc cctcctttga agatcctgac tatcctgttc cccctatttt
     3601 cttccgtcaa aaaccgttgg ctttttcctt attttttcac gccaaaaaat gcagaaaaca
     3661 gctcattggt attgactggt ccgtcatgtt ttttcgcccc atccccggtt ccgcgatatg
     3721 tctccatccc ttttcccggc tgaaatccaa agaagcgttc aaactggctc atatccggag
     3781 ctgcatttcc cggtctctct ctttgttccc gggagtcttc ccttttagcc gttcctcttt
     3841 cctttttttc ttttcggaaa gaatcatact gtttcctttt ctctgcatca cccagaatcc
     3901 cataggcttc ctggatctca tacatctttt tatttccatc cgggtcatcc tgtaccacat
     3961 ccggatgata ttccttagcc agctttcggt aagcggcctt aatatctttt tctgttgcct
     4021 gaggaaggac cccaaggatt ttatagtaat caagcatttt ttctttcctt atcaaaaagg
     4081 ggctgccttt tcggcagccc ctgcatgttt acacgctgta tccgccttcc acagcgatct
     4141 gcgccatctt gtcctttttc tgtttgatga tgagccggaa tgttcctaca ccttccgtat
     4201 ctccgtagtt ttctttataa tccactacaa acgcattggg atatgtatat tttctcacta
     4261 cctgagaagc tgcaatcacc tcaacggtca ccttccggta acagtcagac ttttctgctg
     4321 gtactaagga ccagagtccc aactgtcttg tagaatcaaa aggatctcca tctactgcag
     4381 ttaatatctt tcctgaaatt tccacagtgc tccccagatc ggtggaacgc gcgttggaat
     4441 caaggggaat atctgtctta aactttactc ctgtaatact gatggtccct aagtcaatgg
     4501 tagacgggcc ttctactttt aatgtaaatc ccataatctg ttccttcctt tcttttattc
     4561 ttcctgatta ttctccgctg aatccgcctt caaatttaag agaagccatt ttatccttct
     4621 tctgcttaat aagaagctta aatactccgg ttcccgtttc atcggtaaaa tcttccctgt
     4681 aatcaaccac aaatgcattg ggtaccgtta tctgacgaac cacctgggat gcatttacca
     4741 cgtcgatctg aacattccgg tagcagtctg aattttctgc gggaactaaa gaccatctgg
     4801 ccagcttgct ggtatcatcg gcggcctcac cgcctactgc tgccagtatc ttcccttcaa
     4861 tcaacaccgt tgaaccaaga tctgttgatc tggcgttgga atcatgggga atgtctgctc
     4921 caaatactac attggtaatg ctcgtttcgc gcagttgtac ggtttcactg cctgtgattt
     4981 tcattctaag tcccatatta cgtcctccat tcttaataaa tgatttttat aatccataaa
     5041 gcctttctaa tactggcctt cggatatctg atgtttgaaa taaagctttt atttgtattt
     5101 ctttctgatt cctttataaa ttgtataccc tgcaattaca aaaaatataa ttgtcacaat
     5161 tgtgctgacg tttccataca tgattgttcc caccttccat atgattgtga gtggacaata
     5221 cctggtatta tttacgcagt ctgtcccttt cttgtcagct ccaccttaag atttctggtt
     5281 gtgttgctga acgtcagctg tatgttgcag atgccgtttt tctcatcaat gctgaaatcc
     5341 agctcatctc catcctggag cagggaattg acatactgac ggtttgcatc ccatttactc
     5401 ttctggctgc tggggttatt gctgaaaaac tgtaaaatct tatcctgttt gaagtctccg
     5461 ctgtaaaatc tgagcattct ctcaatatat gtaaccagaa gggttttata aatgggttca
     5521 aattccgtcc cattgcttaa taaatttctg gctttgtaga ccatgacatt cttaatctcc
     5581 ctgcctttat gctgagcatt atcagaggtg aatacaaatc caaaacctgt attgttaatg
     5641 gaatttttaa tggcattggt aaatccggat atctcctttg tcatgctggt cgtgactaaa
     5701 agtgcattgt ctcctgcttc tatgtcataa cgcactcccg ggtattccat ggtggtatta
     5761 ggaaacctct gctttaggta ttccggacac tgccatgctg cagcgatacc ggcagccccg
     5821 taggcagctc ccacatatac tccctcgatc cacatcttca taatgtcctc tttttcctgg
     5881 gaaagagtca catttccatt gtcatcaatg accatccgtt tatccaggat aagtcctgac
     5941 ttatcctttg gtatgatggt aacattggga atgcagggaa ctacaaattc actgtaatct
     6001 ctcttcataa gaggagcgca tttatcctta aaaataccaa ttccctcagt agccacataa
     6061 ttaaacgtac tctcttctcc ggtagcgaag ctgaaaaatg ttgtaatctt ataggggtta
     6121 atggcattca tcaaaattgc aaggttttcc atggtattgg ttcccggttt ttttactttc
     6181 tgatttcctg caaaccgcat tctctgaagc ttaccatctc ctgtctgatt tagttctaca
     6241 tccggaacaa ttccaaacca aagagtattt tcaaattcat ttttatcatt tgtcgtattt
     6301 aaataggtta aaagccttgg caaattgctg gattttatca tcatttccaa aggagtgttc
     6361 gtaatcagga gccttggctg cattcccttc tcttttacct tgtactggtc aaagtacgcc
     6421 tttacaccca ggattttttc aatcaatggc tttaccgctc ttataaaatc atccttgctc
     6481 tttttataaa attcaagata ggtattgtaa ttttgtactt ctacctcccg gtctacggag
     6541 ctttccattg tggaagaaag ggggcagaag gtcctgacca ccagctctct gacatagtcg
     6601 gacttgttct cattaagggc atcgtaatca tcccggaatg tctgaattaa actggtattg
     6661 atgtggtcat ctacaatcgc aagctgagtt ccttcttcct gtttcatttc caggattttc
     6721 agttctccgt cgtctcccat acttaaaagc ccagctttaa attcctggcc tctttgggca
     6781 gtctccccat ttcccagaag caggcgggtc ttgatatctt caatcgcaag agggagcata
     6841 gccaaaacat tattgtaatt gtgacttgcc tgttcaaact ggtaattcag cttgtcccct
     6901 aaatcaaggc gcttgggatc ttcctcctcc agccccatgt aattcccata agtatattgg
     6961 atctctctcc gcacctgacg gatatcttcc ataatctttt taggggagat catctctaaa
     7021 acattgctga atttaaaatc cacatttgct actcccaacg aacctcttgc atcctgtaat
     7081 gtaatgagca tgttgagtaa atcattcatc tcattaagcg gtatttctgt aatgcagtta
     7141 tccggtatat tctccggttt gatcagactg tactgaatac tgccggtatt tgcatcacac
     7201 caggaataaa caaccggagc aaacttctcc aaaaaatcct caaaactttc taccagaagc
     7261 gtttcattga tttccttaat tttgtcatca tcaaggcttg tcttccctct tacatcccca
     7321 atcagggtca gaagattcag cttttcagga ttcatttcag aaaacagaat ggtccggtta
     7381 gtttgtgtaa tagtttccat acgcttttgc tccctctttc tcacttttat tcaatcgctt
     7441 ccatcagctg ttactggcgg gaaacgtgaa catcacagtt cttatctcag gctgttacag
     7501 cctcatctat tgaatcatgg aaatatagtg aatctccaga tcataagctc catccggaga
     7561 tgtaatggat atgatatcac caaagcttac gctgtactgt atctttttgc acataatgga
     7621 acttccgatc ataagcgaag actctgaaga atgatacaaa atcatcctcc tgtcttcatc
     7681 cgctatgagg aatatgtgat ccagtcccag ggattcagaa gcgcctggat attctttcat
     7741 taagtctcca aggcttaccc ggttatcctt gatcttatac atgggaaatg taagaggagg
     7801 tatctcctct tcttcctccg gctgctccat aaaataggca tccatttttc cctggaatcg
     7861 gttctgagct ttcttttccg taatcacttc cagttcaggc tttggtttat gaaacagtct
     7921 ccaaatgaca gcacctgcgg ctgccagaac gagaacaata acccaccagt atgctttcca
     7981 caatgggatt atctccaagg aataggtata ggatattgct gcctctccat cagatatctt
     8041 cagtatcaga tttcggcttc ctgcttttac cggtttaata gtaaggattc cattattcag
     8101 accgacctct gccagatcac cggcatcctg ttccaaagta taaaaaatac cgtctccatc
     8161 agaatcaata aaataattgt taagtaccaa ctgtttttcc ctggataaag gattataatg
     8221 aatgttcttt ggaagttctc ccgtaggagg tgtgttaatc acctgaattc ttactgtatt
     8281 aaagatgcaa gactccatcc tgtcatccaa acgggcttct atgtaataag tccctgactg
     8341 ggttaatacc atttctcctg caagaatccc ttccttgacg gtggtttcaa catcccttct
     8401 gtcactgtcc gactgcccgt ccggataaat caccaccttt ggagtgaagt tcgcataaaa
     8461 ggcctcgtcc ttgatcacag acccgctttt atccttaaaa tagatcttat aagacaatgg
     8521 cttgtttctt gcaattgctg tttctatttc cataacagga gtcaggtccc ggtagctgat
     8581 cagataaatc tttagctcct gattctttct tgtattggtc tgtatgttca tttcactgat
     8641 atcttttttt atgtctgata cttttgccac agaatagtga accagattaa ccggttttat
     8701 ctgctgctct ccgtaaacaa ccgtagtatc tccaatttgc tgaggcgata tcatcaggac
     8761 gtccatctca tctaaatgag aatcatcaag cttaatgcga aggctctggc tgccttctcc
     8821 ataaatgccg cccgcaattt cctgaatacg gtaagccatg ttgtcatgaa aaatcccata
     8881 cagtacttca atcaaggttt ccggcttttc aaccgtataa ttttgtcctc ctgtctggct
     8941 ggaaatttcc ttcagaatct ctttgctgcc gtcatatttg ccgaaagcca ccgtataaag
     9001 cggtatattc cgggatcggc aggcctctac cgtatttctt aagtcctgat cagagatttc
     9061 tctggtcctt ccggcccggg aaccttttaa atccgtttct ccatccgaga ttagaacaat
     9121 catgcacttt cgtccgtttt cctgtccggt cagaccatat gcatagttca atcctaaacc
     9181 aatgtccgta tttcccgaat atccggcgga atccatcaga gcttttaatg catccctctc
     9241 ttcctgagtc ctcacagaaa caggagccgc agatgacaca atatggtcat tatatgctac
     9301 aaacccaatt cggatatcag cactgtggac tgtatcaata aacgctttta ccataccgat
     9361 ggcagtgtga tccggatcat tggcagacat agagccgcta tagtccatga caaacatgac
     9421 atccagaccg tttttcccac ttgctatttc ctctccagac gaacaaaacg agatagaaat
     9481 aaaaaagaga caacttaata aaaatgaaac tgtcttgaac cttttcataa attcttacac
     9541 acctttatcc tatggtcttt tcttgtttgt cttattctca gaattttgtt ccgtgtaatg
     9601 cagttaatac catcaatctg ctcataaggc agcattcata ccgtgctttt atttttccac
     9661 tttcctaaaa tcataagtat gtacacaaca tccaccgtca aggcgattaa aaaggaatac
     9721 cttaagaatg ataaaagcgc tgttgtaaaa taagctatcg taatgatact aagagactgc
     9781 cttaacttac ttttgaaata agcatcttct tcttcattaa catctctgtt tttatcgttc
     9841 acaggttttg taagccaaaa ggctatcaat cctcccccca tcatgattcc cgataccgca
     9901 agtgatacat tcatgtactt tacaagcaac atggatcctg tcgtaacagc aaaggaaaac
     9961 aaaaagcaat gactgaattt gtccaaatgc aaccctccgg cataggaacg caacacacag
    10021 aataccaaaa aaaacacaac tgcttccagc ttcatattaa gacaaagtgc gatcgctata
    10081 tttgccaata cccccatcag catttctaat gtcacctgtg ctgcgtattc gtaggtttca
    10141 aatgatactg atgataagct atctctttta tatgcatacc ttgccaacat gagttcaaac
    10201 cttttcaccg attaaaacct cttaaacttt ctaacatctt ctgtcatttt tggctgatga
    10261 gatatccagc aacaacgagc atttgcgcta taaagaatta ccgataaaat taaaaaatta
    10321 aacactgaat gattcctttt aagctttttc ataaatccca taatatagcc tcctctatgc
    10381 tttttttaca atatactaca tttttcgaga ttttttccta tcatgtaatt attaacggtt
    10441 tatatgtcat tttaggtttt atttttgaat aaaaatttaa gtaaagcctt tgcagtatcc
    10501 ttgcgcccaa taaaaaaacg aaatgacatc cggcttatgc accaatatca tttcgtcttt
    10561 catacaatcg ttcttgttat taaataaagc tatatatcgt catataatat agtctccagt
    10621 gaaaatatat ctccttccca atccagcttc acttgcccat ggtatctttt tgcaatcttc
    10681 ttcatcgaat aaatccccca gccatgaaaa gactcttcct tccggcttac cagcctgtgt
    10741 tccttatcat gctctatttt tccctgatag cggtttctaa caaaaatata caaatatcct
    10801 ttttcatggg ttatctctat ccagatctct cgcttatctt tttctacata ctcagaggcc
    10861 tctaccgcat tatcgaaggc atttcccagc agtaccccaa gatcttcatc tttaattttc
    10921 ataaccccag gtacttccag ctttgtatgt aaacgtatct cttttttact ggttttttcc
    10981 catatatggt ttaccatagc gtctattatt aaattccctg tttttgactc caatcgacca
    11041 atgctcactg actgacctat caaattctcc aaagttgtta ataatttttc tttttggtca
    11101 gatttcacaa gctcttgcaa atagattaag cgctgtttca tatcgtgctt catttcctgt
    11161 atttctgccg acgctgcttc ctccaaatca tgctgtcttc catagtattc cagttgcttt
    11221 acatacatat gggcatttct cttcacctga atcgtttcca ctaatcttaa ataaatggga
    11281 taaatggata gattcataat tgttaatatc aatgcagcca tcagcagcca gccaaaggaa
    11341 tccgttactt ttctatccga cgtttctacc agcatataaa atacgggata caggatcagt
    11401 cctgataaca aaaaaatggt taaataggcg cctccgccat agggaaccat tccgcctcca
    11461 tggcggttca tgaaccaacg gattcccatc actattaaga acagtaaaaa ttttgcaaaa
    11521 atagagttaa tcataaatga tggattttgc ccattattca aaaataaata gcctgcatcc
    11581 ccaattccct ccaaaagcat ccacatcatt acaaaagtta taggaaatgt aaaccgcttc
    11641 cacaagattc cttcataaga aataatgcca actgacaaaa ctgtcgttaa tgtcaatatc
    11701 aggtttatta cgggatggaa atatatcaat tccatattta tgcaaaactg ccatagaaaa
    11761 aaaagagccc agccggccac tcccgcatat cggcttttct ttgcaagaaa aatatccaga
    11821 tacactttca gtaaaagcgt agaatacaat gacatgctaa tgcttgtgaa aatcatcttg
    11881 actgcattca ttttttacct ctttttatac tgcctcaatt tatcatccac cgccttttta
    11941 tacgccctgc ttaatggtaa gatgattcct ttcggcattt ccacctcttc ataccccata
    12001 cggataacat gctggtaatt taccagatat gatttatgta tccttaaaaa tttccctttg
    12061 ctgttttcca gatttttttc tatcttattc aatgctttat attcttttaa aagaccatct
    12121 tgcaaagcaa tttccgccac tcgaagcttg ctttcaaaat acagaatatc acggattaac
    12181 actttataat ccgatttctt atattggaaa cggtaatacg aatcctgctc ttccacaatc
    12241 cttaaaacat aataaaaggt ttcttcaaat tcattctttt ttataggctt tgtaagaaaa
    12301 ccaattggag ctacccggaa ggcgtctttc atgtagccat catgagatgt tacatacacc
    12361 atctgtactg tacggtctat ttcacgtatt ttatatgccg cttccaggcc attcatatat
    12421 ttcatccgta catccaaata gattatatca aaccgccttc cttcgattac cgcctgaacc
    12481 agatcgctcc catcttcata acactccact tctacttgaa ttccggcatt cttcccaagt
    12541 tccagcaagt attcctccag ccttttcaac aagtaaaact catcatcaca aacagcaatc
    12601 tcaatcacaa tctttttccc ctgtaaataa aactttgcgg cccggcgcgt atgccggaca
    12661 ttgtgtctat caaactatga acaattttat ggccaatatc cttcttaaca tattacagtc
    12721 cagtacaaga cgttttttcc taaaattaat tcagcatttc tccctatttt aattatcgtc
    12781 acaacagctg ttttccataa atttttatac attaaaccga tgataccatt atagatttaa
    12841 caaaattcta tgtcaatacg tattccggtt tagctgaatt agtttttttc tataacaatc
    12901 gatcgatcgt gcgaaaataa ggctgttatt atcccctata cagtattcat aaaaaaccaa
    12961 aaaggaactg tatgataccg ttccttttga tcttctttca ttattctatt ctttccgtta
    13021 tcagcctttc accgacccag ctgtaagccc ttctatcata tatttctgag caaaagtaaa
    13081 caaacacatg gtagggatca atgacataat ggttcctgct gccatttccc cccatttaat
    13141 atcatatttt aagatcaggg cattaagccc taccggtatt gtcttaaatt tgtccacatc
    13201 aataaacata accgacataa aaagttcatt ccaggaattg atgaacgcaa agatgaatgt
    13261 ggcggcaatg cctggcataa tgaccggcac aatcacctga aacaatgcct gcaaatagcc
    13321 gcagccatca atccatgccg cttcttccag agatttgggc actccgtcaa aaaagccgca
    13381 taacgtcaca acggaaaatg gtatcatcat attggtatac agcattgcca ggccatacag
    13441 attattcagc atccgcatct tgcctaacat ctgatacaac ggcgccagca tgatgaacat
    13501 gggtatcatc tgggtcacca gaaaaaacag cagcagcaca tttttaaagc ggaaacggaa
    13561 tctgctgatg acgtaactgg ccagaatgga tatgaaaacc gagcaggctg ctgcaacaga
    13621 agatgtaaaa aatgaattgc ataaatatct tgcaaaatta cctttccaga gcattgccgc
    13681 gtaattgacc aaagagaccg gatccggtaa atatttcacc gggaatgcgt aaatctcgcc
    13741 ctgagatccc tttaaggaag tcagcagcat ccataggaaa gggaacatgg tcagcacaag
    13801 aaaggcagtt agtacgacaa acttaaataa tctccacatc tgttttttac tcgctgcagt
    13861 catacgtcat gcctccttat ccgtatattt ggtaagtgtt aagtaaaacg aagcaaatat
    13921 cataagaaac aggatgcaca gcacacccac ggcggaagcc atgccatagt ccagactctg
    13981 gaccagctgc atcatgtagg aagtgatgat attggaagaa cccgccggtc ctccctgtgt
    14041 catggaataa atcagatccg gaaaattaaa gatccagatc actctgagta aaaccgtcag
    14101 caataacacg gaacggatac aaggcactgt gattgcggaa aacttctgaa acgggtttgc
    14161 cccatccaca tcagcagctt catatagttc ttccggaacc cctcttaagg cagccgtgat
    14221 catgattgta aaaaatggga tcccatacca tatatttgct ataatacagg aatacagcgc
    14281 cgtattctta cttgccagcc agcctacagg aaggcggatc aagtgcaatt tcatcagcag
    14341 gtcattaatt acgccggagg taccgttaaa catccagcgc cacatgattc cgataataaa
    14401 tccggagact gcccagggga aaaaaatcag gccctggtac acaccgcttc ccttaaactt
    14461 cttttttaag agcagtgcca tggcaaaccc tgttacaaac tggaaaaaca gggaaatccc
    14521 cacccacttg acggtattcc acatggtgga atagaaggtg ttgctggcac tgtgttcaaa
    14581 tagcttttta aaattatcaa atcccaccca tttgatgttt ttaatattca tcaggttata
    14641 gctttggaag gccatcatgg aacccctgat cataggatag taagtaaata taataggaat
    14701 gatgacggcg ggaagaacca taagaaagat aaaacaggct ctttttaatt gcagtctcga
    14761 tttttgtttc ataccgcttc ctcctcttta ctgcctttct tccataagaa gtctggaagg
    14821 agacctttct ccttccagaa acttcttatg aaaatttaat tcctgtctag cgctttattt
    14881 cttaatgctt accacttctg accttcatcc tgatatgctt ttgtccagaa ttcatccagc
    14941 cattttaaca gatcatcatc tgtgatctcg tcggtcaaat acttctgata catggtatcc
    15001 acttctgttt tataggtagc aaatgcttcg tacatctgag gatatgccgc atgacggtaa
    15061 acttccggtt cttttgccat atccatatac atggcaaacc gtgcctctga aaaataactg
    15121 tctttttctg ccgcgttgct gtgaatcgga atggtggaat aattcttggc aaaatatgta
    15181 ttattctcgg aattggacaa gtacaaaagg aaatctgctg cctcatcggg atgctccgta
    15241 aaggatgtca taccccagcc ggcaaatccg tttggaaaaa ctgcctgccc ggatggtccc
    15301 ttggggaagg gaaccagatc ccactggtca tcctgtaaat cagcggagca ggtcgcaatc
    15361 acttccggat cctgaatcag catagaggtg gttcctccaa caaagccttg taccatttcg
    15421 gaaaagcccc atgctatgga atccgtagga gatgcatttt taaatagatc cttatagaaa
    15481 tgaagtgctt cctttacctc cggcaatgta aaaatggttg ccccattgcc atcctttaaa
    15541 aaataaccgg cattggaatc tgcaagctta tcggtaccga tccagctcca gtagattgta
    15601 tccgcatact ggtaaccgct tgtgccgccg cggaacgaat aaccaaagcg gctgcttgcc
    15661 ggatccgtaa tggcaacccc tgaatcataa atgtcctgcc aggtttcagg ctgcttcaag
    15721 cctttttcct taaaccagtc ggccctgtag taaagacctc tctgatagaa tccataaggg
    15781 accatgtaag ctccgtcttt catataatgg atcacttcct tggccgaatc tgtcaaagtg
    15841 tctttttctg accagctatc caaatatttc tgaagatctg caatccattc attggtgaca
    15901 aactgggtga ttgtggaatc tctcacttct acaatatcca caccgcttcc attcatcagc
    15961 atctgggtga ttttggcatc ggcattctcc aacggcgggg acacaatatc aatcttgaca
    16021 ttgggatgct ctgtttcata cttatctgca atttcccgta aaataaccgt tcgttccgga
    16081 cttgtcaggg actctaccag gctgatggtg accgtttccc ccgtctttcc gctgtcttcc
    16141 ttggtgcttt ctgtctttgc agtttccccg cttgctgatg ttgtcgcttc tgtggctgtg
    16201 tttccgctgc atcctgacag aaccgccgcc actgccagcg ccaatgctgc tgctctcttt
    16261 tttctcatct tttctcctcc ttttatttgt tttgcttata tttgagcaag agccgattcc
    16321 aaatctgaaa tcagggcctc tgtaccttcc aatccgcaat gaattcggat aatcttctgg
    16381 gagccgccca aaaccttgca tcgatcctct tccatccttg catggggtaa aaatgccaga
    16441 ctttcaaacc ctccccatga tacaccgatc ttaaatatcc gaaggctttc cgctagtttt
    16501 tcagcgtcct ttaaggttcc atgaatctca aagcttaaaa gtcccgtatt tcctgactgt
    16561 tgtttcttca tcagcaggta ttggggatga gattccagac cgggataata cacgttcttt
    16621 actttgggat gggtttccag gaacctggcg accgccatcg ctgtttcctg atgctgtgca
    16681 atgcggacag ccattgtgcg aagtccgcgg atcatcagcc aggcctccat gggtcctgca
    16741 ataccgccta acagttccct gtttgctgtc agtttcttca tcaaaccagg atccttcact
    16801 gccagcatgc ctccgatgat atcactgtgg cctccaatat actttgaagt ggtgtgcatt
    16861 acaatatctg cgccaagagt aaggggctgc tggtaaatgg gagtgcagaa cgtattgtca
    16921 atatagacaa gggcctgatg tttttttgcg atattggaga ccgcttcaat gtcctggagg
    16981 gaaaatacaa gagaagaagg gctttccaga acaattaagt ctgttttgtc cgttatgttt
    17041 tcttcaaatt cctccaaaca gtctcccttt acaaaggtgg tggaaatgtc catgtgttct
    17101 ttgcagtatc cggtcagaaa atctcttaac ggaccatagg aattatggat gcatattaca
    17161 tgactgcctg ttttgcatac ggtcagtact gctgttgttg cagccgccat gcccgacgca
    17221 aatgccaggg ctcctgctcc atgctccaaa gccgcaattt tatcttccag aatcctgact
    17281 gtgggattct gtactctgcc gtaacaatat ttgtgtttat ccgtccggtc aaaatcatag
    17341 tattcatcta tggtttcaaa tacattaagg gaattcatga aaatcggcgg aacaaccgca
    17401 ttatagtaat gctcatattc ctctccgtaa tgggctgtaa ttaatttatc actttttaag
    17461 taacggctct gatctgacat atttctacct cttttctcat ttgattcttt gtcctatatg
    17521 ctatatgcta taatataggt taatttgtta taaaacatat ttgatgtatt ataaatcatt
    17581 atatctgctt tttaatatcc cggtacactg catctaacaa ttgttcattg atgatctgtg
    17641 ctttcttcac attttttccc cggatcgctt catacagttt ttcatgcaat ggcaggcttt
    17701 ctaaaaaagg atcttccata ttgaggggaa attcccagaa ctgatccatt acatggctga
    17761 tggacaaaat caactgatac ataatatcat tatgggacaa acggtatatg gtataatgga
    17821 acagtttgtc ctcttctgtc tgccttaccc cctgatgata tttttccatt aataccttgg
    17881 taatatcacc cagttctttc agttcttctt cggtaaccgt atgtatcacc attcggagga
    17941 tttcacgttc cagaatctta cgcacttcca gagcttctaa aagctttcct ttttccttgg
    18001 taaaatcaat cagtgataaa aatgcactgt ccttctgact gcctacgtac acaccctttc
    18061 cattcctcac ttccagaaca ttacgcgcct ccagggtctt catggcttct cttaaggaag
    18121 ttctgcttac ccccatcatt tccagcagct gttcctggga aggaagcctg tctcctgctt
    18181 ttaaatcatt ttcttcaata taattctgta tataacgaat aatctctaac tgaagggatg
    18241 tccgttgtat cttattagcc atctgttatc tctcgcatct ctttatttac gtttaactta
    18301 ccacacgatg ggttatatgt caatattaat taatttttat tttttctcct cattttcatg
    18361 tgcataatgt acaaatatca tccaatatat cttttttgca tgatggcttt ctgctttttt
    18421 gatatataca gaaaaagacg cgacagtttc ttgccacgcc tttgtattgg tcaaattata
    18481 gtcatgagtt ctctctgtgt caataccatt ccattggttc tttgaattat tatgcggatt
    18541 catttgaaaa tgaatcaata ccatttgcgt gcttcaataa aaaagacgtc cggcccactc
    18601 cgcaaatccg tgatgtccag ccgagcgcac aaatttacag ggaccgtata actaatgtga
    18661 gtaatacggt ccctgttctc agactacctt attttccggc atcccccttt tattgcacac
    18721 actgacgtag aatctattct aacacatata ccatcttttt caaatcatca gccttttcct
    18781 gcgcagccac aggttgtcat cttttctttc acaaatcgtt ttactttact gataccggct
    18841 gaaccgtatt ttttaggatc aatagtatcc gggttctcct tcagcacttc ttttacacct
    18901 tcactgtaag caattctcag ttcagtcgca taattcactt tacatatgcc gcgttcgatt
    18961 gccatcttca cggtttcatc cggcacacct gaggcaccgt ggagcaccag cggtatagca
    19021 actgccctgg caatttcgga taaccgctcc aaatccagtt ttggttcgcc cttgtagata
    19081 ccgtgtgctg taccaatcgc caccgcaagg gagttcacgc cagtcttctc gacaaacgtt
    19141 ttcgcttctt ccggatctgt gtaggcactg ccttcgcctc catctaaatc atcctccttg
    19201 ccgccaacct tcccaagctc cgcttcaacc ggtatattgg aaggcataca ggcttcgaca
    19261 acgcgtctgg atagttcaat gtttgcttca aaagcttcat gggaaccgtc gatcatgatc
    19321 gaagtgtaac cggtccgcag tgcctgcatt gccagtctaa aatcagatcc atggtccaga
    19381 tgcagaacca cggggacttt tgcccgctcc gccgcggttt ttacatttgc cagatacaag
    19441 tccagtcccg catatttaac agtagaaggc gttgtctgca aaatcactgg ggcattcaac
    19501 tcctcggcag cctggatcac cgccatgacc atctccatat tttcaacatt aaatgcccct
    19561 actgcataac gaccgttcct ggcatctgac aatatttgac tagttgttac taaaggcat
//
