LOCUS       c00033_NZ_RHHM..       20633 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_RHHM01000004.1 Erwinia psidii strain IBSBF 435 scaffold_4, whole
            genome shotgun sequence.
ACCESSION   NZ_RHHM01000004
VERSION     NZ_RHHM01000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:32:56
            Original ID  :: NZ_RHHM01000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 146213
            Orig. end    :: 166846
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20633
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[156213:156846](+)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10633
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="1"
     cand_cluster    1..20633
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20633
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="Autoind_synth"
                     /tool="antismash"
     CDS             complement(210..389)
                     /locus_tag="ctg33_133"
                     /transl_table=11
                     /translation="MTEIVLRQCQRALMASGMRRRIAANTALQPVITLLLQVSRVNACG
                     SAGTVALIPLATIV"
     PFAM_domain     603..1049
                     /aSDomain="BCSC_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05420.13"
                     /description="Cellulose synthase operon protein C
                     C-terminus (BCSC_C)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_134_0001"
                     /evalue="5.70E-41"
                     /label="ctg33_134"
                     /locus_tag="ctg33_134"
                     /protein_end="149"
                     /protein_start="0"
                     /score="140.8"
                     /tool="antismash"
                     /translation="MAGYYYKLIDENNRRVTVGLNGMLWRYAHDLSNYSLGQEGYYSLQ
                     CYQSLGVPLTYRQRTENGSWELGGTVSFSHARRRDESGYPLDFGVLASDNPAGSDSSSS
                     GVGYTLQAMVERRLSIHWTLGVGVDLQHSKDYTASHALLYVRYSM"
     CDS             603..1115
                     /locus_tag="ctg33_134"
                     /transl_table=11
                     /translation="MAGYYYKLIDENNRRVTVGLNGMLWRYAHDLSNYSLGQEGYYSLQ
                     CYQSLGVPLTYRQRTENGSWELGGTVSFSHARRRDESGYPLDFGVLASDNPAGSDSSSS
                     GVGYTLQAMVERRLSIHWTLGVGVDLQHSKDYTASHALLYVRYSMAGWQGDLAKPVQPL
                     TPYADLD"
     CDS             1277..3316
                     /locus_tag="ctg33_135"
                     /transl_table=11
                     /translation="LRVSRSLTIKQMATVSGVAAVTICIFIVIQLFHFVQQRRTDYAQQ
                     MENIAHTVRQPLSHAVLKADISQAGMILSSLKPAGILAQAEVVLPNGMQALHTDFEPTR
                     PVPELIARLFELPVKITVPLYSLEPSNPKPMALLVLQADSWRVYQFILNALSTMVTTWL
                     LLALILSVSVSWCINRLIVRPLRAIAAELQDLPPQEVISHQLVLPKYHRDDELGMLIRG
                     YNRNQQIAESVYSEMSRLTTRFSLTNLPNKALFLALLDEHLNSLSGDESSTVLILRVET
                     LLEANGVVADEQRDALLLTLLERVRSGIDSHTIVGQISGSDLVLLARRANSPFRAMRLA
                     RQLLQRLNQPVTLQQMQLRPNVSIGLAQRDDSQLNAQDFLSRAVSAMMSARHQGKNQIL
                     FFDPAMMERAHRRLTQEYDILQGLAEHKFCLFLQPQVDMRDGQLVGAEALLRMRQPDGS
                     WLLPEDLIVNAEEIGVIGSVSRWVFEESCRVLAAWQKAGVTLTLSVNLSATQLREPDMV
                     VHLRDLIERHGIVPGSLILEITETAQVGEPELALRMLGELQQLGVSVALDDFGMGYANL
                     NWLSQFKSLPISKLKMDRSFVCLLPHDDTMVKIVSAIAEIIKLDVIAEGVETPQQRDWL
                     LARGIFIAQGYLYSEALPVQTFNEKYFPAHQVASDPATSIADAS"
     PFAM_domain     1382..1738
                     /aSDomain="GAPES3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17154.6"
                     /description="Gammaproteobacterial periplasmic sensor
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_135_0002"
                     /evalue="1.50E-48"
                     /label="ctg33_135"
                     /locus_tag="ctg33_135"
                     /protein_end="154"
                     /protein_start="35"
                     /score="163.8"
                     /tool="antismash"
                     /translation="QQRRTDYAQQMENIAHTVRQPLSHAVLKADISQAGMILSSLKPAG
                     ILAQAEVVLPNGMQALHTDFEPTRPVPELIARLFELPVKITVPLYSLEPSNPKPMALLV
                     LQADSWRVYQFILNA"
     aSDomain        1991..2473
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg33_135_0001"
                     /evalue="7.80E-11"
                     /identifier="TIGR00254"
                     /label="ctg33_135"
                     /locus_tag="ctg33_135"
                     /protein_end="399"
                     /protein_start="238"
                     /score="39.9"
                     /tool="antismash"
                     /translation="RLTTRFSLTNLPNKALFLALLDEHLNSLSGDESSTVLILRVETLL
                     EANGVVADEQRDALLLTLLERVRSGIDSHTIVGQISGSDLVLLARRANSPFRAMRLARQ
                     LLQRLNQPVTLQQMQLRPNVSIGLAQRDDSQLNAQDFLSRAVSAMMSARHQGKNQIL"
     PFAM_domain     2009..2467
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_135_0003"
                     /evalue="1.40E-16"
                     /label="ctg33_135"
                     /locus_tag="ctg33_135"
                     /protein_end="397"
                     /protein_start="244"
                     /score="60.8"
                     /tool="antismash"
                     /translation="SLTNLPNKALFLALLDEHLNSLSGDESSTVLILRVETLLEANGVV
                     ADEQRDALLLTLLERVRSGIDSHTIVGQISGSDLVLLARRANSPFRAMRLARQLLQRLN
                     QPVTLQQMQLRPNVSIGLAQRDDSQLNAQDFLSRAVSAMMSARHQGKNQ"
     PFAM_domain     2531..3226
                     /aSDomain="EAL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00563.22"
                     /description="EAL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_135_0004"
                     /evalue="2.40E-55"
                     /label="ctg33_135"
                     /locus_tag="ctg33_135"
                     /protein_end="650"
                     /protein_start="418"
                     /score="187.7"
                     /tool="antismash"
                     /translation="ILQGLAEHKFCLFLQPQVDMRDGQLVGAEALLRMRQPDGSWLLPE
                     DLIVNAEEIGVIGSVSRWVFEESCRVLAAWQKAGVTLTLSVNLSATQLREPDMVVHLRD
                     LIERHGIVPGSLILEITETAQVGEPELALRMLGELQQLGVSVALDDFGMGYANLNWLSQ
                     FKSLPISKLKMDRSFVCLLPHDDTMVKIVSAIAEIIKLDVIAEGVETPQQRDWLLARGI
                     FIAQGYLYSE"
     CDS             3530..4810
                     /gene_functions="transport (smcogs)
                     SMCOG1212:sodium:dicarboxylate symporter (Score: 505.5;
                     E-value: 1.6e-153)"
                     /gene_kind="transport"
                     /locus_tag="ctg33_136"
                     /transl_table=11
                     /translation="MKTSLFKSLYFQVLTAIAIGVLLGHFWPELGAQMKPLGDAFVKLI
                     KMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEVVSTIALIIGLVVVNVLQPGAG
                     MNIDPATLDAKAVAVYTQQAEQQGVVAFLLDIIPGSVIGAFASGNILQVLLFAILFGFA
                     LHHMGDKGTLVFNFIESFSRVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLLQLGQL
                     IICFYITCVLFVVVVLGLIARVVGFNIFKFIAYIKEELLIVLGTSSSESALPRMLDKME
                     KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNAHMDIFHQVTLLVVLLLSS
                     KGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLIGNGVATVVVA
                     KWVDQLDEKQLNETLSTAGKAKKLSEI"
     PFAM_domain     3554..4732
                     /aSDomain="SDF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00375.20"
                     /description="Sodium:dicarboxylate symporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_136_0005"
                     /evalue="4.30E-113"
                     /label="ctg33_136"
                     /locus_tag="ctg33_136"
                     /protein_end="401"
                     /protein_start="8"
                     /score="378.4"
                     /tool="antismash"
                     /translation="LYFQVLTAIAIGVLLGHFWPELGAQMKPLGDAFVKLIKMIIAPVI
                     FCTVVTGIAGMESMKAVGRTGAVALLYFEVVSTIALIIGLVVVNVLQPGAGMNIDPATL
                     DAKAVAVYTQQAEQQGVVAFLLDIIPGSVIGAFASGNILQVLLFAILFGFALHHMGDKG
                     TLVFNFIESFSRVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLLQLGQLIICFYITC
                     VLFVVVVLGLIARVVGFNIFKFIAYIKEELLIVLGTSSSESALPRMLDKMEKLGCKKSV
                     VGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNAHMDIFHQVTLLVVLLLSSKGAAGVTG
                     SGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAKW"
     CDS             5044..6543
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_137"
                     /sec_met_domain="Peptidase_M16 (E-value: 7.6e-10, bitscore:
                     33.0, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3.6e-19,
                     bitscore: 63.5, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQGTRIRLLVGGLLLTAASGFVQAETLQPDPAWQQGKLNNDFSWQ
                     VLATPQRPSDRVEMRLMVNTGSLMENAQQSGYSHILPRLALVHNAKLDTAQQRSLWQQS
                     IDPDRPQPPAMTSYDYTLYSLSLPNNRPEVVKEALSWLAATVGGMSINQQTVNAALNVG
                     DPISSWPANPQDVWWRYRLKGSALLDHDPLKPASAPVDPEKLNAFYKQWYTPDAMTLFV
                     VGNVDSRSLVEQINKTFSPLQGKRSTPTPVPALPPLPTHPISLINGNLNQDRLSLVWDS
                     AWQPIRDSQNLQHYWQSDLAREALFWHVQRVLSENKVQKVQVGFDCRVLYQRAQCAINL
                     DADNATLVSNLTLVAHEMANIRDNGLPQEEFDALMAQKTAELSKLFATYARTDTDVLMS
                     QRLRSQQNAVVDIAPEQYQKLRQNFLAGLTLQMMNQELRQQLSQDIITVLMQPQGEAET
                     DVQMLQQNWQKIMQPAAHAQVPSNTLDEARPEVSDIPASQN"
     PFAM_domain     5188..5517
                     /aSDomain="Peptidase_M16"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00675.22"
                     /description="Insulinase (Peptidase family M16)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_137_0006"
                     /evalue="2.60E-08"
                     /label="ctg33_137"
                     /locus_tag="ctg33_137"
                     /protein_end="158"
                     /protein_start="48"
                     /score="34.1"
                     /tool="antismash"
                     /translation="TPQRPSDRVEMRLMVNTGSLMENAQQSGYSHILPRLALVHNAKLD
                     TAQQRSLWQQSIDPDRPQPPAMTSYDYTLYSLSLPNNRPEVVKEALSWLAATVGGMSIN
                     QQTVNA"
     PFAM_domain     5641..6174
                     /aSDomain="Peptidase_M16_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05193.23"
                     /description="Peptidase M16 inactive domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_137_0007"
                     /evalue="1.50E-17"
                     /label="ctg33_137"
                     /locus_tag="ctg33_137"
                     /protein_end="377"
                     /protein_start="199"
                     /score="64.3"
                     /tool="antismash"
                     /translation="VDPEKLNAFYKQWYTPDAMTLFVVGNVDSRSLVEQINKTFSPLQG
                     KRSTPTPVPALPPLPTHPISLINGNLNQDRLSLVWDSAWQPIRDSQNLQHYWQSDLARE
                     ALFWHVQRVLSENKVQKVQVGFDCRVLYQRAQCAINLDADNATLVSNLTLVAHEMANIR
                     DNGLPQEEFDALMAQ"
     CDS             complement(6607..7482)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066:alpha/beta hydrolase domain-containing protein
                     (Score: 56.3; E-value: 4.5e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_138"
                     /sec_met_domain="Peptidase_S9 (E-value: 4.3e-15, bitscore:
                     49.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTEIINIWPTGDAPGASDSQVQPQIIDLAEEYQPHDRAASGVRC
                     PEIAFWHPEESNGTTLLVAPGGAFEQIMIDKEGSALAMFFTNMGYTLAVMTYRFPQDGH
                     HEGADAPLADAQRAVRILRHRASQGLNGKRVVMMGFSAGGYVAGSVGTRFAEKCYPVQD
                     IADSLSARPDALVLIYPVISMREGLAHPDSRQRLLGEHPTQKEIDNWSLETRVTEETPQ
                     TLLIHAVNDRSVPINNSMVMFSALREKKVASELHFYEQGGHGFGIRNVADLPLASWPML
                     VNEWLRARKW"
     PFAM_domain     complement(6685..7191)
                     /aSDomain="Peptidase_S9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00326.23"
                     /description="Prolyl oligopeptidase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_138_0008"
                     /evalue="3.00E-13"
                     /label="ctg33_138"
                     /locus_tag="ctg33_138"
                     /protein_end="266"
                     /protein_start="97"
                     /score="49.9"
                     /tool="antismash"
                     /translation="RFPQDGHHEGADAPLADAQRAVRILRHRASQGLNGKRVVMMGFSA
                     GGYVAGSVGTRFAEKCYPVQDIADSLSARPDALVLIYPVISMREGLAHPDSRQRLLGEH
                     PTQKEIDNWSLETRVTEETPQTLLIHAVNDRSVPINNSMVMFSALREKKVASELHFYEQ
                     GGHGFG"
     CDS             8675..8911
                     /locus_tag="ctg33_139"
                     /transl_table=11
                     /translation="MEACGSANYRARQFSQFGHEVKQISPQYVAPFRVGSENDLNNAIA
                     IVEADSRPGMRYVPKKALSSRIFSVCTGFASDG"
     CDS             8908..9027
                     /locus_tag="ctg33_140"
                     /transl_table=11
                     /translation="MKNTTSLINPIRGGLEYGIAIPEGAHNIMVCLPDDPEDA"
     CDS             10001..10633
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_141"
                     /sec_met_domain="Autoind_synth (E-value: 3.3e-74, bitscore:
                     242.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELFDVSYEELKTTRSEELYRLRKKTFSDRLGWEVLCSQGMESD
                     EFDGTGTRYILGLCGDKLVCSVRFTDLDRPNMITHTFNACFSTVSLPTAGIESSRFFVD
                     KARVRALLGERFPVSQVLFLAMVNWAQHNGYGCIHTIVSRPMLTILSRSGWQFTLLKEA
                     FLSERERIYLLKLPAGDRDQEQLARGVVARTDCVTDLLTTWPLRLPV"
     PFAM_domain     10028..10558
                     /aSDomain="Autoind_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00765.19"
                     /description="Autoinducer synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_141_0009"
                     /evalue="2.40E-53"
                     /label="ctg33_141"
                     /locus_tag="ctg33_141"
                     /protein_end="186"
                     /protein_start="9"
                     /score="180.5"
                     /tool="antismash"
                     /translation="EELKTTRSEELYRLRKKTFSDRLGWEVLCSQGMESDEFDGTGTRY
                     ILGLCGDKLVCSVRFTDLDRPNMITHTFNACFSTVSLPTAGIESSRFFVDKARVRALLG
                     ERFPVSQVLFLAMVNWAQHNGYGCIHTIVSRPMLTILSRSGWQFTLLKEAFLSERERIY
                     LLKLPAGDRDQEQL"
     CDS             complement(10605..11360)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1197:autoinducer-binding transcriptional regulator,
                     (Score: 146.9; E-value: 1e-44)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg33_142"
                     /transl_table=11
                     /translation="MFSLFRENRTLKDTLRAYIDRKLSPFGELEYAYTVVGKKNPSDVL
                     IISSYPDEWIRLYQTGQFQLTDPVILTAFRRTSPFAWDENITLMSELRFTRIFSLSRQY
                     NIVNGYTFVLHDHMNNLALLSFIIKCNDQGGLEQQQRLSSEQAVLQMLLIDFNEQMYRL
                     AGPDIAGAMKTATAEEKAIFSPRENEVLYWVSMGKTYAEIAVIAGISLSTVKFHMKNVL
                     LKLGVSNTPQAVRLGIELDLIRPAASVAR"
     PFAM_domain     complement(10653..10817)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_142_0011"
                     /evalue="8.40E-16"
                     /label="ctg33_142"
                     /locus_tag="ctg33_142"
                     /protein_end="236"
                     /protein_start="181"
                     /score="57.4"
                     /tool="antismash"
                     /translation="IFSPRENEVLYWVSMGKTYAEIAVIAGISLSTVKFHMKNVLLKLG
                     VSNTPQAVRL"
     PFAM_domain     complement(10884..11321)
                     /aSDomain="Autoind_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03472.17"
                     /description="Autoinducer binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_142_0010"
                     /evalue="3.50E-26"
                     /label="ctg33_142"
                     /locus_tag="ctg33_142"
                     /protein_end="159"
                     /protein_start="13"
                     /score="91.6"
                     /tool="antismash"
                     /translation="TLRAYIDRKLSPFGELEYAYTVVGKKNPSDVLIISSYPDEWIRLY
                     QTGQFQLTDPVILTAFRRTSPFAWDENITLMSELRFTRIFSLSRQYNIVNGYTFVLHDH
                     MNNLALLSFIIKCNDQGGLEQQQRLSSEQAVLQMLLIDFNEQ"
     CDS             12516..13796
                     /locus_tag="ctg33_143"
                     /transl_table=11
                     /translation="MSSRWLIFALSLTAGVLLVTLPVRAVSPAFLDKAVLAQVREQLHN
                     HQASEPTQQAWQQLKRQADKALPLPLMSVTEKGMVPPSGTKHDYLSLSAYWWPDPQHPQ
                     GRWVRRDGEINPASKNNQSDGVRLAAFTARVQTLTLAWYFSGEQKYADRAMALLRYWFI
                     NPASKMNPNLNFAQGVEGVAPGRSGGILDGRYLATRVVDSVIILRSAPGWQQTDEQGIR
                     VWMQDYLSWLKNSKAGKREARAKNNHGSWYNVQVAGIAWYLEDMPLIRQQVRAARSRMQ
                     QQIAADGSQPLELQRTRSFHYSYFNLQALVTLAVLADKAGAGDLWRPDVKDKVAIVTAL
                     DFMAPYIDSSRAWPWPTRDRLGQRLIPLLSQADSSLNSDHYQQWVKQADFTTEDNAQRG
                     ASDNARRDTWLLSLPRFARCQVGRKPC"
     PFAM_domain     12732..13574
                     /aSDomain="Alginate_lyase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05426.14"
                     /description="Alginate lyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_143_0012"
                     /evalue="5.60E-83"
                     /label="ctg33_143"
                     /locus_tag="ctg33_143"
                     /protein_end="353"
                     /protein_start="72"
                     /score="278.7"
                     /tool="antismash"
                     /translation="SVTEKGMVPPSGTKHDYLSLSAYWWPDPQHPQGRWVRRDGEINPA
                     SKNNQSDGVRLAAFTARVQTLTLAWYFSGEQKYADRAMALLRYWFINPASKMNPNLNFA
                     QGVEGVAPGRSGGILDGRYLATRVVDSVIILRSAPGWQQTDEQGIRVWMQDYLSWLKNS
                     KAGKREARAKNNHGSWYNVQVAGIAWYLEDMPLIRQQVRAARSRMQQQIAADGSQPLEL
                     QRTRSFHYSYFNLQALVTLAVLADKAGAGDLWRPDVKDKVAIVTALDFMAPYIDSSRAW
                     "
     CDS             complement(13857..14801)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276:PfkB domain protein (Score: 178.6; E-value:
                     3e-54)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_144"
                     /transl_table=11
                     /translation="MKQKNIAVIGECMIELSKKNNDIHQGFGGDTLNTAVYLARQAPQS
                     QLHVEYVTALGTDSFSSEMIEAWQQEKIGTSLVQRLENKLPGLYVIETDAQGERTFLYW
                     RNDAAARFWLESEHAGEICQQLAHYDCLYLSGISLAILSPQSREKLLALLATCRQNGGQ
                     VIFDNNYRPRLWQSAAVTQSAYQVMLSCTDIAFLTLDDEDLLWGKASIDKVIARTHAAG
                     VNEVVVKRGSGSCLVSQQGQPLIDVPAIRLATSSVVDTTAAGDSFSAGYLAVRLTGGSA
                     EEAARRGHLTASTVIQHRGAIIPLSAMPVCPPA"
     PFAM_domain     complement(13884..14792)
                     /aSDomain="PfkB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00294.26"
                     /description="pfkB family carbohydrate kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_144_0013"
                     /evalue="2.50E-68"
                     /label="ctg33_144"
                     /locus_tag="ctg33_144"
                     /protein_end="306"
                     /protein_start="3"
                     /score="230.7"
                     /tool="antismash"
                     /translation="KNIAVIGECMIELSKKNNDIHQGFGGDTLNTAVYLARQAPQSQLH
                     VEYVTALGTDSFSSEMIEAWQQEKIGTSLVQRLENKLPGLYVIETDAQGERTFLYWRND
                     AAARFWLESEHAGEICQQLAHYDCLYLSGISLAILSPQSREKLLALLATCRQNGGQVIF
                     DNNYRPRLWQSAAVTQSAYQVMLSCTDIAFLTLDDEDLLWGKASIDKVIARTHAAGVNE
                     VVVKRGSGSCLVSQQGQPLIDVPAIRLATSSVVDTTAAGDSFSAGYLAVRLTGGSAEEA
                     ARRGHLTASTVIQHRGAIIPLS"
     PFAM_domain     15682..17424
                     /aSDomain="AsmA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05170.16"
                     /description="AsmA family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_145_0014"
                     /evalue="2.10E-147"
                     /label="ctg33_145"
                     /locus_tag="ctg33_145"
                     /protein_end="581"
                     /protein_start="0"
                     /score="492.6"
                     /tool="antismash"
                     /translation="MSRTGKIISWIAGTFLLLVIVVAIVIAMFDWNRLKPTINQKVSTE
                     LNRPFAIRGELGVVWQRNRDETGWHRWVPWPHLHADDIMLGNPPDIPEITMVHIQRVDA
                     TLSPLSLLHRQVFIPWIKLQQPDVRLIQTADRHNNWTFSLAGSDNSDPGQKPSAWSLRL
                     DNILFDQGKIAYRDAINKADMQIAVTPLGKPVPYPQVAGSKDDVVSKGASDFVFGWEAW
                     GTYNNEKLSGEGKIGGMLSLRSQTNPFPVQADIRNGTTRVQVAGSLQDPLNLGGLNIRL
                     RFAGDTLANLYGLTGIVLPDTPPYETDGHLIARFRQQAGTEFRYENFNGHIGDSDIHGT
                     MTWRQTTPRAKLEGTLESRQLRMADLGPLIGVKSGKGSDKTEKAKAARGDAASQPADRV
                     LPHDRFDTKSWRVMDADVKFSGKRIAHSDSLPLSDLYTHLVLKDGDLLLDPLRFGMAGG
                     HLNTTIHMAGDSAPMRVRADLHARNLKLKQLFPGVKAMQSSMGQMNGDATLSGTGNSVA
                     DMLATSNGELKLLMNDGVISRSLMEIVGLNVGNYVVGKLFGDDQVRINCAAADLNITNG
                     LASSR"
     CDS             15682..17748
                     /locus_tag="ctg33_145"
                     /transl_table=11
                     /translation="MSRTGKIISWIAGTFLLLVIVVAIVIAMFDWNRLKPTINQKVSTE
                     LNRPFAIRGELGVVWQRNRDETGWHRWVPWPHLHADDIMLGNPPDIPEITMVHIQRVDA
                     TLSPLSLLHRQVFIPWIKLQQPDVRLIQTADRHNNWTFSLAGSDNSDPGQKPSAWSLRL
                     DNILFDQGKIAYRDAINKADMQIAVTPLGKPVPYPQVAGSKDDVVSKGASDFVFGWEAW
                     GTYNNEKLSGEGKIGGMLSLRSQTNPFPVQADIRNGTTRVQVAGSLQDPLNLGGLNIRL
                     RFAGDTLANLYGLTGIVLPDTPPYETDGHLIARFRQQAGTEFRYENFNGHIGDSDIHGT
                     MTWRQTTPRAKLEGTLESRQLRMADLGPLIGVKSGKGSDKTEKAKAARGDAASQPADRV
                     LPHDRFDTKSWRVMDADVKFSGKRIAHSDSLPLSDLYTHLVLKDGDLLLDPLRFGMAGG
                     HLNTTIHMAGDSAPMRVRADLHARNLKLKQLFPGVKAMQSSMGQMNGDATLSGTGNSVA
                     DMLATSNGELKLLMNDGVISRSLMEIVGLNVGNYVVGKLFGDDQVRINCAAADLNITNG
                     LASSRLFVFDTENAVINITGTTNFANERMDLSINPESKGIRIITLRSPLYVRGTFKNPD
                     AGVKAGPLLARGVAAVALGAVVTPAAALLALISPSDNEQNQCTNVLQQMKGKK"
     CDS             complement(17833..18525)
                     /locus_tag="ctg33_146"
                     /transl_table=11
                     /translation="MPVAMQERNNDQPWCFPLPLIEENQRFISYRADGPVILEKPGQNN
                     ISAAPVNGLTTQSHLKTVNKTPLHITFDANNKSKKGLRIKDIAQSDKVMNSVNGIITGI
                     KKSLVNREVSSQHKSSEYNVISHYERIDDKSPAIGQRFTSASEGPGLPDNAEHNVSDTR
                     TYRLQKLEFRRTGTLSHIAATLPVPLLNMSNKNSITLDQHLGEIEFLYDNDIDILPTDI
                     KRRINILY"
     CDS             complement(18576..19331)
                     /locus_tag="ctg33_147"
                     /transl_table=11
                     /translation="MSHTTPLVKLASDALKTDSRLTISEALQRLAKEIKPKEAVHLTTS
                     NSVSAFFGVALGGTPFVPGWFAGIVANLSDRYGLTLSKTDEDHIRLSFNNQNQRALTGI
                     AGTGQGLEKTLLDANSVNYMTVMPAEANAIMVVQNLCGNNFSFNLTQEDFDKFVTQLAC
                     EEIAPELQKQIISEAESEKITENGFILKIEAKSELRLQAGKMVNDNTFMVMPRTAVGAS
                     LALDFLKVQNSSHQKAKKMKMIIQYLLIS"
     CDS             complement(19427..20539)
                     /locus_tag="ctg33_148"
                     /transl_table=11
                     /translation="MLKRSHSTSDARYFIDTHNVTRRHSFSSGKENSYLEKIEKIKSSL
                     AEFKHSDAILNLHLAFQPDLAEIAYSDARVEDISAKDFVYCGTAVALPVNKAGILLDKE
                     GRLMLIKGKEYNLFKGLIVKYTSGYKYQIAPLITGKQDIRFSHLYMNDKGLLIGDEKET
                     GKSHIIKISTPEHSDKSEKQYISIGLEEYNKNNISDDLMFKVDENTFVSYFFSDNKLYL
                     KSIRTDKQDKDISILSHEIFLPLKKNCTLASVKRSQNHLQIEIKKGNKTRIYYINPAHI
                     SNRKLLIKKSAISHHKTSHLALVTILTRNTMQVIHSPQTEKVILVANMCLFFPPLLIIS
                     GCTIKRPGTFWQVQGMGKRQFKVPDRLILG"
ORIGIN
        1 aacgcacggt ttatgcctca gatggcagga aaatgtgacg gtgacggaag gccgttgcgc
       61 ctcctcacct accggtttac tgcgagtaag ccacccagtc cccgccgtta agccgtctcc
      121 agggtttgcc ctgatatata acaaccacgg cgttatcatc tctgacgcca cctgcgaccg
      181 tgacaggctg tcgcacaggc ggattatgct cagacgatgg tggcgagtgg tatcagcgct
      241 accgtcccgg cagatccgca ggcgtttacc cggctgacct gcaatagcaa agtgatgact
      301 ggctgaagcg cagtattcgc agcgatgcgg cgacgcatgc ccgatgccat gagagcacgc
      361 tgacactggc ggaggacgat ttccgtcatc aggactccgg ggatatttct gattttaccg
      421 cccacaccac catgatgcag ctggagatgc catggtctga agggaaaggc tttctgcggc
      481 tggataatgt cgatgtctcg gcgggaactt tttcacctga tgcatcgggt aatattgccg
      541 ataacatggc tacctgtgcc aacgatgacg cggcctgtcg ccctgatttc cgccagtagc
      601 tgatggcggg ctattactat aagttgattg atgaaaataa ccgccgggtg acggtgggac
      661 tgaacggaat gctgtggcgc tatgctcacg atctcagtaa ttattcgctg ggtcaggaag
      721 ggtactacag tctgcaatgt tatcagtcac tgggggtgcc gctcacttac cggcaacgta
      781 cagaaaacgg gtcatgggag ctgggcggca cggtgtcgtt ctcgcacgcc cgtcgccggg
      841 atgaatcggg ctatccgctg gattttggcg tgctcgccag tgataatccg gcggggagtg
      901 acagcagcag cagcggggtt ggctacaccc ttcaggcgat ggtggaaaga cgcctgagca
      961 tacactggac gctgggcgtg ggtgtggatc tccagcattc gaaagattac actgccagcc
     1021 atgctctact ttatgtccgt tattctatgg caggatggca gggcgatttg gcgaagcctg
     1081 tgcaaccttt aacgccttat gccgacctcg attagccagc agaggggcgg ttcacggtga
     1141 aggctgcaag gttatatcct gaaaaaggct gccccgctcg attccctgag gggcacttaa
     1201 caggtgttcg ccatcagata tacccaggga cagttttttc gccggtatgg cggtcccagc
     1261 attgcggaga acaggcttgc gcgtgagtcg ttcgttaacg ataaagcaga tggcgacggt
     1321 ttcaggtgtt gcagccgtga ctatctgtat ttttatcgtc attcagcttt tccattttgt
     1381 gcagcagcgc aggaccgact acgcccagca aatggagaat atcgcgcata ccgtgcggca
     1441 accgctctcc catgcggtgc ttaaagccga tatcagccag gccgggatga tcctctcgtc
     1501 gttgaaacct gccgggatac tcgcgcaggc cgaagtggtg ctccccaatg gtatgcaggc
     1561 tttgcatacc gatttcgaac ccacccggcc agtgccggaa ttgattgccc gcctgtttga
     1621 gcttccggta aaaattaccg tgccgctcta ttccctggag ccatctaacc cgaaacctat
     1681 ggcgctgctg gtattgcagg cggattcctg gcgggtttat cagttcattc tcaacgcact
     1741 gtcaaccatg gtaacgacct ggctgttgct ggcgttgatt ttgtcggtgt cggttagctg
     1801 gtgtatcaac cggttaattg tccgtccatt acgggcaatt gctgccgaat tgcaggatct
     1861 gcctccgcag gaggtcatct cgcatcagtt ggtgttaccg aaatatcacc gggatgatga
     1921 gcttggtatg cttattcgtg gctacaaccg caatcagcag atcgcggagt cggtctacag
     1981 cgaaatgagt cgtctgacta cccgattttc actgaccaat ttgccgaaca aagccctgtt
     2041 tcttgccctg cttgatgagc acctcaattc gttgtccggc gatgaatcgt ccaccgtact
     2101 gattttgcgc gttgaaaccc tgctggaagc caacggcgtg gtagcggatg aacagcgtga
     2161 tgccctgttg ctgacgctgc tggagagggt caggagcggt atcgacagtc acaccattgt
     2221 ggggcagatc tcaggcagtg acctggtgtt gttggctcgt cgggctaaca gcccgttccg
     2281 cgcaatgcga ctggcacgtc agcttctgca acgcctgaat cagccggtga cgcttcagca
     2341 gatgcaactt cgtcccaatg tcagtattgg gctggcacag cgtgatgaca gccagctcaa
     2401 tgcccaggat tttctcagcc gtgccgtctc agcgatgatg tcagcgcgcc atcagggcaa
     2461 aaatcagatc ctgttttttg acccggcgat gatggagcgg gcgcacagac gcctgacgca
     2521 ggagtacgat attttacagg ggctggctga acacaagttc tgtctgtttc tgcaaccgca
     2581 ggtggatatg cgcgatggtc agctggtggg ggcggaagca ttactgcgta tgcgtcagcc
     2641 ggatggtagc tggttactac cggaagattt gatcgtcaat gctgaagaga ttggggtgat
     2701 cggttcagtg agccgctggg tatttgaaga atcctgtcgg gtactggcgg cctggcagaa
     2761 agccggtgta acgctgacgc tcagcgtcaa cctctctgcc acgcaacttc gtgaaccgga
     2821 tatggtggtg cacctgcgcg atttgatcga gcgccacggc attgtaccgg gtagcctgat
     2881 actggaaatc actgaaacgg ctcaggtcgg ggagccggag ctggcgctgc gtatgctggg
     2941 tgaattgcag cagctggggg tatcggtggc gctggatgat tttggcatgg gctatgccaa
     3001 cctgaactgg ctgagccagt ttaaatcgct gcccatcagc aagctgaaaa tggaccggag
     3061 ttttgtctgt ttattgcccc atgacgacac gatggtgaag atagtttcag cgattgccga
     3121 gataatcaaa ctggatgtta tcgcggaagg ggtggaaacc ccgcagcaac gtgactggct
     3181 gttggcgcgt ggcatcttca tcgctcaggg ctatctctat tctgaagcgc tccccgttca
     3241 gacatttaat gagaaatatt tccccgcaca tcaggtggcc tcagacccgg ctaccagcat
     3301 tgctgacgcg agctgaacct gttctttcca ccacggtctc ttttttcctg cgccagacta
     3361 tccagagcct gacggtagct gaagtgattc agctcttaaa accgtaggtt agttgcatca
     3421 gggcgtctca attcatatta atttggttaa cggggtgtta cttttgcgtt gatgtttgac
     3481 gataactaca acgaacccac ccgtcattaa gccgttaacg gatattgcta tgaaaacttc
     3541 tctgtttaaa agtctttact tccaggtctt aactgctatc gctatcggtg tgctgcttgg
     3601 tcatttctgg cctgagctgg gtgcgcaaat gaagccatta ggcgacgctt ttgtaaaact
     3661 gattaagatg attatcgccc cggtcatctt ttgtaccgtc gtcaccggta ttgccggaat
     3721 ggagagtatg aaagccgtgg gtcgaacggg tgcggtggcg ttgctttatt ttgaagtggt
     3781 cagcaccatt gcgctgatta ttggtctggt ggtggtcaac gtgttgcaac ccggtgccgg
     3841 aatgaatatc gatcccgcca cgctggatgc caaagcagtt gcggtgtata cgcagcaggc
     3901 ggaacaacaa ggcgtggtcg ccttcctgct ggatatcatc cccggcagcg tgatcggtgc
     3961 ctttgccagt ggcaatattc ttcaggtgct gttgttcgcc attctgtttg gtttcgccct
     4021 gcatcacatg ggtgataaag gtacgctggt tttcaatttt attgaaagtt tctcccgcgt
     4081 tatcttcggt atcatcaata tgatcatgcg cctggcaccc attggtgcat tcggtgcgat
     4141 ggcgtttacc attggtaaat acggcgtggg ctcgctgctc cagctgggcc agctgattat
     4201 ctgtttttat attacctgtg tgctgtttgt ggtggtcgta ctggggctga ttgcccgcgt
     4261 ggttggtttt aatatcttca aatttatcgc ttatatcaaa gaggagctgc tgattgtact
     4321 tggcacctct tcctctgagt cggccctgcc gcgtatgctg gataagatgg aaaagctggg
     4381 ttgtaaaaag tcagtggtcg gcctggtgat ccctaccggc tactctttta atctggatgg
     4441 cacctcaatt tatctgacta tggcggcagt atttattgct caggccacca atgcccacat
     4501 ggatattttc caccaggtta cgctattggt agtgttgctg ctttcctcaa aaggggcggc
     4561 gggtgtgact ggcagtggat ttatcgttct ggcagcaacg ctgtctgccg tggggcatct
     4621 gccggtggcc ggactggccc ttatcctcgg tatcgatcgt ttcatgtcag aagcgcgtgc
     4681 gctgacgaat ctgattggta atggtgtggc gaccgttgtg gtagcgaagt gggttgatca
     4741 gctggatgaa aaacaactta atgagacgct ttctacagcg ggaaaagcta aaaagctgtc
     4801 agaaatctga cattaagctg ttaattgtct aaaagacctc acaaatgccc gctgcgactt
     4861 gccctcgcag cgggcatttg cataataacc ctcgaagatt ttatcatttt tcactttccg
     4921 gtgagactta ctgacctgga cgtggtctaa gaggctgttc ttctttttaa cagcgtttcc
     4981 tgctgacagt agcaggcgga ccatcagtga ttatttttgg tttgtgattg agtaggggtt
     5041 tacatgcagg gcaccagaat tcgtcttttg gttggtggat tactgctgac cgctgccagc
     5101 ggctttgtac aggctgaaac actgcaaccc gatcccgcat ggcagcaggg aaaactgaat
     5161 aatgatttca gctggcaggt gctggcaaca ccacagcgcc ccagcgatcg tgttgaaatg
     5221 cgcctgatgg ttaataccgg ttcattgatg gaaaatgccc agcagagcgg atacagtcat
     5281 atactgccgc gtctggcgct ggtgcataac gctaagctgg atacggccca gcagcgttcg
     5341 ctgtggcagc aaagtatcga tcccgatcgt ccacagccgc cggccatgac ctcttatgat
     5401 tatacccttt attcattgag tctcccgaat aaccggccgg aagtggtgaa ggaagccctc
     5461 agctggctgg ccgccacggt aggtggtatg agcatcaacc agcagacggt taacgcggcg
     5521 ctcaatgtgg gcgatcccat ttccagctgg cctgccaacc cgcaggacgt ctggtggcgc
     5581 taccgtctga aaggctcagc gcttctggac cacgatcccc tgaagcccgc cagtgcaccc
     5641 gtcgacccgg aaaagctgaa tgccttctat aagcagtggt acacaccgga tgcgatgacg
     5701 ctgtttgtgg tcggtaatgt tgacagccgc agcctggtcg aacagattaa taaaacgttt
     5761 tcaccgttgc agggcaagcg cagcacccca acgcctgttc cggcgttgcc gccacttcca
     5821 acgcatccga tcagtctgat caacggcaat cttaatcagg atcgtctttc tctggtgtgg
     5881 gattcagcgt ggcagccgat tcgtgattcg cagaatctgc aacattactg gcagagtgac
     5941 ctggcacgtg aggcactgtt ctggcacgtt cagcgcgttc tgagcgaaaa caaagtgcaa
     6001 aaagtgcagg tgggttttga ctgccgggtg ctgtatcagc gtgctcagtg tgccattaat
     6061 ctcgatgcgg ataacgcaac gcttgtcagc aatcttacgc tggtggcgca tgagatggcg
     6121 aatatccgtg ataacggtct gccgcaggaa gaatttgacg cgctgatggc gcagaagacc
     6181 gcagagctaa gcaagctgtt tgctacctat gcccgcaccg atacggatgt gctgatgagc
     6241 cagcgcctgc gttcacagca gaatgcggtg gtggatattg caccagagca gtaccagaaa
     6301 ctgcggcaga actttctggc tggtttgaca ttacagatga tgaatcagga gctgcgccag
     6361 cagctgtcgc aggacatcat cacggtactg atgcagccgc agggcgaagc ggaaaccgac
     6421 gtgcagatgt tgcagcagaa ctggcaaaag attatgcagc cagccgctca tgctcaggta
     6481 ccctctaaca cccttgatga agccaggccg gaagtgtccg acatccctgc gtcacagaac
     6541 tgagaggtgt gacgaatgcg ccggccttgt ctctgaaggg acgctggcgc ggaggcattc
     6601 cttacctcac cacttacgcg cccgaagcca ttcattcacc agcatgggcc agctggcaag
     6661 cggcagatcg gctacgttgc gaataccaaa accgtggccg ccttgctcat agaagtgcag
     6721 ctcgctggca actttcttct cacgtagcgc gctgaacatg accatgctgt tattaatcgg
     6781 cactgaccga tcgtttacgg cgtggatcag caatgtttgc ggtgtttcct ctgtgacacg
     6841 ggtttccagt gaccagttgt caatctcctt ctgggtggga tgttcgccca gcaggcgctg
     6901 acgtgaatcc gggtgtgcca gcccctcacg catactgatc accggataaa tcagcaccag
     6961 cgcatcgggt ctggcggaca gtgagtcggc tatatcctgt accgggtagc atttttcagc
     7021 aaagcgcgta ccgacgctcc ctgccacata acccccggca gaaaagccca tcataaccac
     7081 acgcttgccg ttcagaccct gtgaggcacg atgacgcagg atgcgaacgg cccgttgtgc
     7141 atcagccagc ggggcatcgg ctccttcatg gtgtccatcc tgtgggaagc ggtaggtcat
     7201 gactgccagc gtatagccca tattggtgaa gaacatcgcc agtgcgctgc cttctttatc
     7261 aatcattatc tgttcaaacg ccccgcctgg cgcgaccagc agcgttgtgc cgtttgactc
     7321 ttccgggtgc cagaaggcga tttccggaca gcgcacgcca gaggcggcac gatcgtgagg
     7381 ctggtattcc tctgccagat caataatttg tggctgcacc tgtgaatcac tggcaccggg
     7441 agcatctccg gtcggccaga tattgattat ttcagttttc atcgatactc ctgtttatcg
     7501 tttttagtat ggcaaagtcc gcaaagaaat cgtcatacgg gtgcaatata agcattgccg
     7561 ataaattatt atttcgtcca gaaaatatcg cagatgccac tgtgtttcag actatgcctg
     7621 aataaggtat taaataacga agatctcagt tatttatcag gatgatttgc tgacatatat
     7681 accttggttt aaatatgttt attatttcac cttaagttaa attgaggcaa tatttataat
     7741 attcatgtca ttagttggta tctcttcttc attcttaatt ttctcatctg gccttttatt
     7801 cgccatagtg aagtattgtg agattatact tttctgctga gggaaatatg acatcggcaa
     7861 cggtgaaaat gcccggcaat gtgacgtctg tttcaaccgg tttatgattc aacgctggat
     7921 ttcattttac aaggcgaatg tgtcagaaag gggaacatga ttgcggtata cctgttggca
     7981 gaatcgaaat gcataaataa tctttaacct gtatctcgtt tgcacgagac gtaataaaga
     8041 taagttattt atttcagagt attgatttcc atatcaggaa aaatccacaa tcatttcaga
     8101 ttataacgta aataatgatc tttaaaatgt gccaaaataa taacggtgca atttatttaa
     8161 ccttatatga tgaaatgaga taaatttttg tcgatatatt tcagttgctg aaaattgatt
     8221 tattcagagt ggttttttca ttaatattta tacggatttt aactttttaa ctgtagagcg
     8281 gtaatatttt ttttaccaga aaaaataaac agctacgttt gacaccgcta cagtgaccga
     8341 ttgtggataa tatttgttca gttagcagct aaggcccaca gaaccgtatg atggctggac
     8401 ttttacctgt tgaacgccct ttgcgcggta aaggagggaa gcactattgc acgctaatga
     8461 catggacatc tccccatgca ggcttcagtg ggccatgctg taagcgcaaa ccgaccgcaa
     8521 aataaagagg tgtcccgtgg aacaaattat cggaattgat ctggcaaagc gagttttcag
     8581 gttcatatcg tttctctaca gggtgaaaag aaggtcaaca aaatgcttac ccgtgagaac
     8641 ttttatcgct cagccaccat tgtccagaat tattatggaa gcctgtggca gtgccaatta
     8701 ccgggcacgg cagttcagtc aattcggaca tgaagttaaa caaatcagtc cgcaatatgt
     8761 ggctcccttc agagtgggaa gtgaaaacga tttaaataat gccatcgcta tcgttgaggc
     8821 tgacagccgt ccgggaatgc gttatgtgcc aaaaaaagcg ttgagcagca gaatattcag
     8881 tgtctgcacc gggttcgcca gcgacggatg aaaaacacaa cgtccctcat caacccgata
     8941 agagggggcc tggaatacgg tattgccatc ccggaaggcg cacataacat tatggtctgt
     9001 ctgcctgatg acccggaaga tgcataaaat gaactggcga caccaggccg ccagctgttc
     9061 cacgagatgc tacagggact gcatagcagt cagcagcggc ggacgtaggt cttgcccata
     9121 tcagtcagca aaatgagaat accgtcaggc tacagggaat accgggtatc gggccaccgg
     9181 gggcatcagc gctgatcgta ttactgggtg acagcagtga ttttcaacat ggctggtact
     9241 ctggggccgg tcccgaagga gcacagcagc ggcggaaagg tcaaactcag gggaataacg
     9301 aaacgcggga acagtgacct gcgagggtta cttatccatg gcgcccgttc cgtggtgtga
     9361 cgcgtcgtaa acctccctga tgaacgttgt agcggccggt aacgctggct gaagggaata
     9421 atcatccgaa atggcgtgaa taaagcggtt gtggcccagt attttcctgg tagtacggtc
     9481 atctcagaag gtgtttttta ataactgatc tgattaacac cgatgatatt ttcataaata
     9541 accataaata accataaata aactgatgcc tgcaactggc agcaatgaca tgcccgcgct
     9601 attaagttgc atttcacgca cagatccact ggaattgcac gatattttat atttatccat
     9661 aatggttttc gtacctgtaa acatataaaa tacagcaaaa tttttttgac gaagagccat
     9721 gagtcaattt gactgtcttt cattaagtat cgtatgtgga tttctggaaa aaattgtttt
     9781 tataagcgca atcgagtttt ttatttttat gtaaaagatg acatttttta acaacacaat
     9841 ttattcattc tttattaaaa atgtggaatt agtctcacaa atcgctttgt attccttctc
     9901 agtatcaatt gaatatggga tcatatggtg ctgatctggt gtgtaaaaaa ttgtagaatg
     9961 tcactcgtca ggccagagcg gccgtatcag gaaatataaa atgcttgaac tctttgacgt
    10021 cagctatgag gaactgaaaa ccacccgttc agaagaactc taccggctgc gaaaaaaaac
    10081 cttcagtgac cgcctcggct gggaagtatt gtgtagccag ggcatggagt cggatgaatt
    10141 tgacggcacc gggacccggt atattctggg cctgtgcggg gataaactgg tgtgcagcgt
    10201 gaggttcacc gatcttgacc ggccgaacat gatcacccac accttcaatg cctgcttcag
    10261 cacggtcagt ctcccgactg caggcattga gtccagccgt ttttttgtgg ataaggcacg
    10321 cgtacgcgcg ttgctgggtg aacgctttcc cgtcagccag gtgctgtttc ttgccatggt
    10381 gaactgggcg caacataacg gttatggctg catacacact attgtcagcc gccctatgct
    10441 aaccatcctg agccgttccg gctggcaatt tacgttgctg aaagaagcct ttcttagtga
    10501 aagggaacga atttacctgc tgaagctgcc agctggagat cgtgaccagg aacagctggc
    10561 acgcggtgtt gtcgccagaa cagattgcgt aaccgacttg ctgactacct ggccactgag
    10621 gctgccggtc tgataagatc aagttcaatg ccaagccgga ccgcctgtgg ggtattactg
    10681 acgcccagtt tgagaagaac atttttcata tgaaatttaa ctgtactcag ggatatcccc
    10741 gcaatgactg cgatttcggc ataggtttta cccatactga cccagtacaa cacctcattc
    10801 tcccgcggtg agaagatggc tttctcttcg gctgtcgcgg tcttcatcgc cccggcgata
    10861 tcagggccag ccagccggta catctgctcg ttgaaatcaa tcagcagcat ctggagcacc
    10921 gcctgctcag atgacagtcg ctgctgttgc tccagtcctc cctgatcatt gcatttgata
    10981 atgaacgaca gcaacgccag attattcata tgatcatgca gcacaaacgt atatccgtta
    11041 acgatattgt actgccggga cagggaaaag atgcgggtga agcgcagctc tgacatcagg
    11101 gtgatgtttt cgtcccaggc aaacggagag gtccgtctga atgcggtgag gatcaccgga
    11161 tcggttaact gaaactgccc cgtctggtaa aggcggatcc actcgtcagg gtaactggaa
    11221 ataatcagta catcggaagg gtttttctta ccaacaacgg tataagcata ctcaagttcc
    11281 ccgaacgggg agagctttct gtctatgtaa gccctgagcg tatctttcag cgttcgattt
    11341 tcacgaaaaa gggagaacat tcaggctccg tatgactttt catctgcttt taaaacagta
    11401 actataccta agtacaggcc ctctaaaact taagtatagc ttacatatca tgctgaccag
    11461 gttacaatca gtttagctgt taatacggaa aaaaactgac ctgcaaagtc agaccgtaaa
    11521 ataatcaaca ccagggaaaa ccccgaccgg acggaacaca tataaagtct ccgccggaaa
    11581 ggggcctgat cttaccaccc gacagcccac caatcaaacg ccagccacgt cgccagtatc
    11641 cattgcctgc gcgggaacaa tacacactaa caggctctgt cgcattaagg cggtgtcagg
    11701 tatgtgctgt ttttttgtca tctttcctga ctatgtttct gttccgaaaa tatttccgac
    11761 gcctgcatta tcctacagat gttattgtgc agtgtgtccg ctggtatctg gcgtattcac
    11821 tcagcctgcg aaatctgaca gagcgcggca ttattgttga ccattccacg cttcaccgcc
    11881 tggtaccgct gctggccagg gcattctgcc ggcacaaagg tgctgtgggt cgccggtggc
    11941 gaatgaacga aaccgatata ggtgtcagag gacactggaa atatctgtcg ccgttgatac
    12001 tgatggtcag accatcgacg tgctgctgac ggggcaacgg caaccgctct gcgtttcttc
    12061 cgctgtgcca tccgttacca cggtgaagcg gaaacggtga ccctcgataa aagcggcggc
    12121 agcgctgggc atacttcatg ccggaaggcc tgatgaaaaa accatcaccg tcaggcacag
    12181 caattatctg aataacccgg ttaagcagga ccatcgtaca ttaagtgcag gataaaactg
    12241 atggcgggat tcaactcgtt caggcgtgcc cggacgctcc ttactggtat tgagctggta
    12301 tcatatgata cgtaagggca atatcaatat ccgcaaaatg atggattgcc acctgtcgaa
    12361 caatgttatc tgttgagcgt ctgaaaatcc gcaatactac tctgctgact ttgtgtcgtt
    12421 aatacgacag aatccctttt atcgctgtgc cggaaagagg aacgcgattg tttaacgctg
    12481 gcacaactat ccgggttgcg ccgcaggaga aaactatgag ttcacgctgg ctgatttttg
    12541 ctttatctct caccgcaggg gtgctgctgg tcacgctgcc agtgcgggct gtttcgcctg
    12601 cttttcttga taaggctgtg ctggcccagg taagggagca gctgcacaat catcaggcca
    12661 gcgaaccgac ccagcaggca tggcaacagc tgaaacgaca ggctgataag gcgttgcctt
    12721 tgccgctgat gagcgtgaca gaaaaaggga tggtgccgcc cagcggaaca aagcatgact
    12781 atctcagcct gagtgcttac tggtggccgg accctcagca tccccagggg cggtgggttc
    12841 gtcgcgatgg cgaaattaat ccggccagca aaaataacca atcggatggc gtcagactgg
    12901 cggcgtttac cgccagggta cagacgctga cgctggcctg gtatttttcc ggtgagcaga
    12961 agtatgccga cagagcgatg gctctgctac gttactggtt tattaatccg gccagtaaaa
    13021 tgaaccccaa ccttaatttt gcccaaggcg tggagggcgt tgcgcccgga cgctctggcg
    13081 gcattcttga tgggcgatat ctcgccaccc gcgtggtgga ttcggtgatt atactgcgtt
    13141 cagccccagg ctggcagcaa acggatgaac agggtatccg cgtctggatg caggattatc
    13201 tgagctggtt gaaaaacagc aaagccggaa aacgggaagc cagagcgaag aacaatcatg
    13261 gcagctggta caacgtccag gtcgccggca ttgcctggta tctggaagat atgccgttga
    13321 tccggcagca ggttagggcg gcgagaagca gaatgcagca gcagattgct gccgatggct
    13381 cccagccgct ggagctacag cgtacccgct catttcacta cagttacttt aatcttcagg
    13441 cgctggtgac gctggccgtg ctggccgata aagcgggggc tggcgacctg tggcgacctg
    13501 acgttaaaga taaggtagct atcgttaccg cgctggattt tatggctccg tatatcgaca
    13561 gcagcagggc gtggccctgg ccgacacgcg accgtctcgg tcagcggctg atccccctgc
    13621 tttcgcaggc agacagtagc ctcaacagcg accattatca gcagtgggtg aaacaggccg
    13681 attttaccac tgaggataac gctcagcgcg gggcatcaga caatgcacga cgcgatacct
    13741 ggttgctgtc actgcctcgt tttgcccggt gccaggtggg cagaaagccg tgttgacagt
    13801 tcagacccgg tgacagccaa cgcctgcccc tttcagattg ccgtcccccg caggagttac
    13861 gccggtgggc agacaggcat ggcggaaagc gggatgattg ccccacggtg ttggatcacc
    13921 gtactggcgg tcagatgccc gcgtctggcg gcctcttcgg cgctgccgcc cgtcagtctt
    13981 accgccagat agcctgcgct gaacgaatcc ccggcggcgg tggtatccac cacgctgctg
    14041 gtggcaagcc tgatggcagg gacatcaatc aacggttgcc cctgttgcga taccagacag
    14101 gatcctgaac cacgcttgac tactacttcg ttgacgccag cggcatgggt tctggcaatc
    14161 accttatcaa tgctggcttt accccacagc agatcttcat cgtccagcgt caggaaggca
    14221 atatcagtac agcttagcat tacctgatag gctgactgtg ttactgccgc tgattgccac
    14281 agccgtggcc ggtagttgtt gtcaaaaata acctgcccac cattctgccg acaggttgcc
    14341 agcagggcca acagcttttc ccggctctgc gggctgagaa tggccaggct gataccgctg
    14401 agataaagac agtcatagtg ggccagttgc tgacatattt ccccggcgtg ttcgctctcc
    14461 agccagaaac gggcggcggc gtcatttcgc cagtagagaa atgtccgctc cccctgtgca
    14521 tccgtttcta ttacatacaa acccggaagt ttgttttcca accgctgaac aagagaagtg
    14581 ccgatttttt cctgttgcca ggcctcaatc atctcactgc tgaaactgtc tgtgccgagg
    14641 gcggtcacat actctacatg cagttgcgat tgtggtgcct ggcgggcgag gtaaaccgcc
    14701 gtgttaagcg tatcgccgcc aaatccctgg tgtatatcgt tgtttttctt tgaaagttca
    14761 atcatgcatt caccgataac ggcaatgttt ttttgcttca tggtcatcaa ctcatcggaa
    14821 atttgcttca gtctcgtcgc actgactggc agagtcaata ttttaaaacg atgttttatt
    14881 ttttatgaag gatggaaata cgctgaaaaa gtcatctgcc tgccaacgcg gttcgcaggc
    14941 taaatctccc cggcgagtaa tgtatttcat cgggctgata cgcattgggg ggatatgttt
    15001 ataccggcaa accgagcgcc agccttttgc catagcgttc aacagtgcgg gggatctcac
    15061 tggcggttaa actatggcct gccttgcgat cactgctcta tcctgttttt cagccaatga
    15121 ctgtgtcgcg tgagggccag ttccgggcga tgtaactgag gtgacagcac ggactcaggc
    15181 aggcgtgtcg gttatcggtt tttcacctgg tgggtatcct gctgctattg ccagcatcag
    15241 gggcgactgt accccttagc cttgtttgta gtgtcattac cgaccggccg atggcttcgg
    15301 ttgtcagaat atcttccggc ttacccttac cgatttttag ccgtgaccgg acagatttgt
    15361 cctggctgac ggttaacccg tccagcgcaa aactgtcagc gataaccagt ctccttcact
    15421 gtcgggcgac gtaggtcgtt acgctgtttt aaatcaccgg gtaccgccgt cttcaaccat
    15481 gttcaccagg cgtttgcagc ctgtaatata ttgctgttca ggtgatgtgc cttgatggtc
    15541 agacgttgct tgctctcaga cagcgtgtgt ctgccctgag ctgtcccgcc cactttccag
    15601 caacctgaca gcccgcctga tgttgtttct gtttgcctcg tctatcttta ctgaacgcag
    15661 aagtatggaa gaggacgaag catgtcacgc acaggaaaaa taattagctg gattgccggg
    15721 acttttttgt tgctggtgat tgtggtggcg atcgttatcg cgatgtttga ctggaaccgc
    15781 ctgaaaccca ccattaacca gaaagtctcg acggaactca atcgtccctt tgctattcgg
    15841 ggggagctgg gggtggtgtg gcaacgcaat cgtgatgaga cgggctggca tcgctgggtg
    15901 ccctggccgc atcttcatgc agatgacatt atgttgggca acccgcctga cattcctgag
    15961 atcaccatgg tgcatataca gcgagtggat gccacgctgt ctccgttatc gctgttgcac
    16021 aggcaggtgt ttattccctg gattaaatta cagcagcctg atgtcagact gatccagacc
    16081 gccgatcgcc ataataactg gaccttcagt ctggctggca gtgataattc cgatcccgga
    16141 cagaaaccgt ccgcatggtc tcttcgcctc gataatatcc tgtttgatca gggaaagatt
    16201 gcttaccgtg atgcgataaa taaagcagac atgcagattg cggtcacccc gctgggtaag
    16261 cctgtgccgt atccgcaggt ggcgggcagt aaagacgatg tggtcagtaa aggtgcatcg
    16321 gattttgttt ttggctggga ggcctggggg acttacaaca atgaaaagct cagcggtgag
    16381 ggaaaaatcg gcggtatgct ctctttgcgc agtcaaacca atccttttcc agtacaggcc
    16441 gatatacgca acggcaccac gcgcgtgcag gtcgcaggca gtttgcagga tccgctgaac
    16501 ctcggtgggt taaatatccg gttgcgcttc gctggcgaca cgctggctaa cctgtatggc
    16561 ctgaccggta tcgtattgcc tgatacgccg ccctatgaga ccgatggtca tctgattgcc
    16621 cgcttccggc agcaggctgg cacggagttc cgttatgaaa acttcaatgg ccatattggt
    16681 gacagcgata ttcacggcac catgacctgg cgccagacaa cgccgcgcgc caaactggaa
    16741 gggacactgg aatcccgcca gctgcggatg gccgatctgg gaccgctgat tggcgttaaa
    16801 tccggtaaag gcagtgataa aacggagaag gcgaaggcgg caaggggcga tgcggccagc
    16861 cagccagccg acagggtgct gccgcatgac cggtttgata ctaaaagctg gcgggtaatg
    16921 gatgccgatg tgaagttcag tggcaaacgt atcgcacaca gtgattcact gccactgagc
    16981 gatctttaca cccatctggt gctgaaagat ggggatttgt tgctcgatcc actacgtttt
    17041 ggcatggcgg gcggtcatct caacaccact atccatatgg cgggcgatag tgcaccgatg
    17101 cgtgtcaggg ctgacctgca cgcccgcaac ctgaagctta agcagttgtt tcccggtgta
    17161 aaggcgatgc aaagcagtat ggggcaaatg aacggagacg ccacgttgag cggcacgggc
    17221 aactcggttg cagatatgct tgcgaccagc aatggcgagc ttaagctgct gatgaatgac
    17281 ggggtgatca gccgcagtct gatggaaatt gttggcctta acgttgggaa ttacgtggtg
    17341 ggtaaactgt ttggtgacga tcaggtacgt atcaactgtg cggcggctga cctgaatatc
    17401 accaatgggc tggcgtccag tcggctgttt gtttttgata ccgaaaacgc agtgattaat
    17461 atcaccggca ccactaactt tgccaatgaa cggatggatc tgtcaattaa cccggagagc
    17521 aaaggtattc gcattattac actgcgttca ccgctgtatg tgcgtggcac ctttaagaac
    17581 ccggatgcgg gcgtaaaggc gggaccgttg ttagcaagag gggtagcggc cgttgcgctg
    17641 ggggcagtcg tgacacccgc agcggcactg ctggcgctga tttcacccag tgataacgaa
    17701 cagaatcagt gtaccaatgt gcttcagcag atgaagggca agaaataagc tgcagcgcga
    17761 tgataaaacc ggccatcagg ccggttttgc aatgcaatta acgggttgat ccctatttat
    17821 cagaggatgg cattaataca atatatttat gcgccgtttt atgtcggtcg gtaatatatc
    17881 aatgtcgtta tcatataaaa attctatttc tcccaggtgc tgatccagag taatgctgtt
    17941 tttgtttgac atgttcagaa ggggcacggg aagcgtggcg gctatatggg acagtgtacc
    18001 cgttctgcgg aattccagtt tttgcagccg atatgtcctg gtgtctgaaa cgttgtgctc
    18061 agcgttatca ggcaggccag gcccttctga agcagaagta aatcgctgcc cgatcgccgg
    18121 ggatttgtca tcaatacgtt catagtggga aataacattg tattcagatg atttatgttg
    18181 actggatact tcccgattga ctaacgattt ttttataccc gtaatgatcc cgttgactga
    18241 attcatgacc ttatcgcttt gggcgatgtc tttaattctg agtcctttct ttgacttgtt
    18301 attcgcatca aaagtaatat gcagcggtgt tttattgaca gtctttagat gactctgtgt
    18361 cgttaagccg ttaactggcg ctgcggagat attattctgt ccaggttttt ccaggatgac
    18421 agggccatca gcacgatatg aaataaagcg ctggttttct tcaattaagg ggagtggaaa
    18481 acaccagggc tggtcattgt ttcgctcttg catggcgaca ggcatgattt gccattcagc
    18541 gaataacgtg gcgtcaaaat ttaatgtggt aacctttaac ttattagcag gtattgaata
    18601 atcatcttca tttttttggc tttttgatgt gaactatttt gcaccttgag aaaatctaaa
    18661 gcaagacttg cacctacagc tgttcttggc attaccataa aggtattgtc attgaccatt
    18721 tttccagcct gtagtcttaa ttcgcttttg gcttcaatct ttagaataaa tccattttct
    18781 gttatttttt ctgactctgc ttcgctgatg atttgttttt gcagctcagg tgctatttct
    18841 tcacaggcta actgcgtaac gaatttatca aagtcctcct gtgttaaatt gaatgagaaa
    18901 ttattaccac aaaggttttg aaccaccata atcgcattag cttcggcagg cataaccgtc
    18961 atgtagttta cactgtttgc atccagtagc gttttctcaa gtccctggcc agttcccgca
    19021 ataccagtca gggcacgctg attctgatta ttaaatgaca gcctgatgtg atcctcgtct
    19081 gtttttgaaa gtgtgaggcc atatctgtca gataaattag caacaatgcc tgcaaaccaa
    19141 cctggtacga aaggagtgcc acctaatgca accccaaaaa atgcggagac agaattgctg
    19201 gtggtcagat gcaccgcctc tttcggtttg atttctttag ccaggcgttg taatgcttct
    19261 gatatcgtca atcgggaatc tgtcttcagg gcatcactgg ccagtttgac taacggtgtg
    19321 gtatgcgaca ttaatctatt gttgttatgt tcgaataagt ccgttttatt ttttacctct
    19381 tttatccggt tgccgaatac accgggaacg gtacggtaaa cgctttctat cccaggatca
    19441 atcgatctgg caccttgaat tgccgcttgc ccataccttg aacttgccag aaagttcctg
    19501 gcctttttat tgtgcaccct gaaattatca acaagggagg aaaaaaaagg cacatattgg
    19561 ctactaaaat taccttttcg gtctgaggag aatggattac ctgcatggta tttctcgtga
    19621 ggatcgttac caaagcgaga tgagaagttt tgtggtggct tatggctgat ttttttatta
    19681 ataattttct gttagaaatg tgcgccggat taatataata aattcttgtc ttgttgcctt
    19741 ttttaatttc gatctgtaga tggttttgcg atctttttac gctggctaat gtgcagtttt
    19801 ttttcaaagg taggaatatt tcatgggaaa ggatagatat atccttatct tgtttatcag
    19861 tacgaattga tttaaggtat aatttattat ctgaaaaaaa gtatgacaca aaagtatttt
    19921 catcaacttt aaacatcaga tcgtcagata tattattttt attgtattct tcaagaccaa
    19981 tagagatata ttgcttttcg cttttatcag aatgttcggg agttgagatc tttattatat
    20041 ggctttttcc ggtctctttc tcatctccga tcaacaaccc cttgtcgttc atatataaat
    20101 ggctaaacct gatatcctgt tttccagtga ttaacggtgc gatctggtat ttgtaacctg
    20161 atgtatattt gactatcaac cccttgaata aattgtattc ttttcccttg attaacatca
    20221 gacggccttc tttatcaagc aagatacctg ctttgttgac gggtaatgcc acagcggtgc
    20281 cgcaataaac aaaatctttc gcgctgatat cctcgaccct ggcgtcactg taggctattt
    20341 ccgccagatc gggctgaaag gcaagatgta aatttaaaat tgcgtcgctg tgtttaaatt
    20401 ctgccaaact gctttttatt ttttcaatct tttcaagata tgaattttct ttcccggatg
    20461 aaaatgagtg acgcctggta acgttgtgag tatcgataaa atatctggca tcactcgtac
    20521 tgtgacttct ttttaacata tttttctcca tgttattaaa taatattttc catgctattg
    20581 atgcatgcta tatgtcttta ttttctttcc ctggctgtga attttctaac tta
//
