GCF_002906475.1_ASM290647v1_genomic - 6 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP026321.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	RiPP-like	38,127	49,053
Region 1.2	ectoine	1,555,264	1,565,650	ectoine	Other	66%
Region 1.3	NRPS	1,921,936	1,962,868	acinetobactin	NRP	39%
Region 1.4	NRPS	2,477,312	2,521,259	amphi-enterobactin 1 / amphi-enterobactin 2 / amphi-enterobactin 3 / amphi-enterobactin 4	NRP	83%
Region 1.5	betalactone	3,070,949	3,102,711

NZ_CP026322.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	RiPP-like	1,527,253	1,538,119

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	RiPP-like	38,127	49,053
Region 1.2	ectoine	1,555,264	1,565,650	ectoine	Other	66%
Region 1.3	NRPS	1,921,936	1,962,868	acinetobactin	NRP	39%
Region 1.4	NRPS	2,477,312	2,521,259	amphi-enterobactin 1 / amphi-enterobactin 2 / amphi-enterobactin 3 / amphi-enterobactin 4	NRP	83%
Region 1.5	betalactone	3,070,949	3,102,711
Region 2.1	RiPP-like	1,527,253	1,538,119

Compact view

NZ_CP026321.1 - Region 1 - RiPP-like

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Location: 38,127 - 49,053 nt. (total: 10,927 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001783.1	0.13	Other	streptonigrin	Streptomyces flocculus
BGC0001133.1	0.08	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001440.1	0.06	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001480.1	0.05	Other	tundrenone	Methylobacter tundripaludum 21/22
BGC0001702.1	0.03	NRP, Polyketide	nocamycin	Saccharothrix syringae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001783.1	0.42	Other	streptonigrin	Streptomyces flocculus
BGC0001133.1	0.31	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001440.1	0.25	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001480.1	0.22	Other	tundrenone	Methylobacter tundripaludum 21/22
BGC0001702.1	0.16	NRP, Polyketide	nocamycin	Saccharothrix syringae

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP026321.1 - Region 2 - ectoine

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Location: 1,555,264 - 1,565,650 nt. (total: 10,387 nt) Show pHMM detection rules used

ectoine: ectoine_synt

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000856.1	0.53	Other	ectoine	Methylophaga thalassica
BGC0000859.1	0.53	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.43	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.39	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.38	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.37	Other	ectoine	Methylarcula marina
BGC0000854.1	0.33	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000858.1	0.33	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.33	Other	ectoine	Streptomyces anulatus
BGC0000919.1	0.14	Other	phaseolotoxin	Pseudomonas syringae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000856.1	0.80	Other	ectoine	Methylophaga thalassica
BGC0000859.1	0.80	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.74	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.71	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.70	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.69	Other	ectoine	Methylarcula marina
BGC0000854.1	0.67	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000858.1	0.66	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.66	Other	ectoine	Streptomyces anulatus
BGC0000919.1	0.43	Other	phaseolotoxin	Pseudomonas syringae

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP026321.1 - Region 3 - NRPS

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Location: 1,921,936 - 1,962,868 nt. (total: 40,933 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000800.1	0.26	Saccharide	xanthan	Xanthomonas campestris
BGC0001399.1	0.26	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000373.1	0.25	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001538.1	0.24	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001444.1	0.22	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001591.1	0.22	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.22	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001135.1	0.21	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.21	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.21	NRP	icosalide A, icosalide B	Burkholderia gladioli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000800.1	0.60	Saccharide	xanthan	Xanthomonas campestris
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000373.1	0.58	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001538.1	0.58	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001444.1	0.55	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001591.1	0.55	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.55	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001135.1	0.54	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.54	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.54	NRP	icosalide A, icosalide B	Burkholderia gladioli

Similar known gene clusters

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 1921935 - 1962868:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1678

Search NORINE for peptide: strict or relaxed

AMP-binding (456..853): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

NZ_CP026321.1 - Region 4 - NRPS

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Location: 2,477,312 - 2,521,259 nt. (total: 43,948 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001890.1	0.60	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001185.1	0.35	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.34	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.29	NRP	paenibactin	Paenibacillus elgii B69
BGC0001149.1	0.25	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001131.1	0.25	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.24	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.24	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000427.1	0.23	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001890.1	0.84	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001185.1	0.68	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.67	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000401.1	0.63	NRP	paenibactin	Paenibacillus elgii B69
BGC0001149.1	0.59	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001131.1	0.58	NRP	ambactin	Xenorhabdus miraniensis
BGC0001844.1	0.58	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.57	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.57	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000427.1	0.57	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 2477311 - 2521259:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_2155

Search NORINE for peptide: strict or relaxed

AMP-binding (475..869): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_2157

Search NORINE for peptide: strict or relaxed

AMP-binding (39..445): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

NZ_CP026321.1 - Region 5 - betalactone

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Location: 3,070,949 - 3,102,711 nt. (total: 31,763 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.20	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.15	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.14	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000871.1	0.12	Other (Nucleoside)	VEPE, AEPE, TG-1	Myxococcus xanthus DK 1622
BGC0001160.1	0.12	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0000375.1	0.12	NRP	indigoidine	Streptomyces chromofuscus
BGC0000389.1	0.12	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001131.1	0.11	NRP	ambactin	Xenorhabdus miraniensis
BGC0000938.1	0.10	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000864.1	0.09	Other	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.52	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.45	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.43	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000871.1	0.40	Other (Nucleoside)	VEPE, AEPE, TG-1	Myxococcus xanthus DK 1622
BGC0001160.1	0.40	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0000375.1	0.40	NRP	indigoidine	Streptomyces chromofuscus
BGC0000389.1	0.40	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001131.1	0.37	NRP	ambactin	Xenorhabdus miraniensis
BGC0000938.1	0.36	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000864.1	0.34	Other	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP026322.1 - Region 1 - RiPP-like

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Location: 1,527,253 - 1,538,119 nt. (total: 10,867 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	RiPP-like	Similarity score	Type	Compound(s)	Organism
BGC0000863.1		0.05	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000934.1		0.03	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0000863.1		0.22	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000934.1		0.15	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names