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Overview
1.1
1.2
1.3
2.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP016321.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RiPP-like | 40,824 | 51,699 |
Region 1.2 | betalactone | 332,470 | 360,515 |
Region 1.3 | arylpolyene | 895,817 | 939,409 | APE Vf | Other | 90%

NZ_CP016322.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | NRPS | 1,447,468 | 1,492,030 | vulnibactin | NRP | 100%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RiPP-like | 40,824 | 51,699 |
Region 1.2 | betalactone | 332,470 | 360,515 |
Region 1.3 | arylpolyene | 895,817 | 939,409 | APE Vf | Other | 90%
Region 2.1 | NRPS | 1,447,468 | 1,492,030 | vulnibactin | NRP | 100%

No secondary metabolite regions were found in these records:
  NZ_CP016323.1

Compact view
NZ_CP016321.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 40,824 - 51,699 nt. (total: 10,876 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001133.1 |  | 0.08 | NRP | taxlllaid A | Xenorhabdus bovienii SS-2004
BGC0000955.1 |  | 0.06 | NRP, Polyketide | althiomycin | Myxococcus xanthus
BGC0001415.1 |  | 0.06 | NRP | althiomycin | Serratia marcescens subsp. marcescens Db11
BGC0001650.1 |  | 0.05 | NRP | Le-pyrrolopyrazines | Lysobacter enzymogenes
BGC0001285.1 |  | 0.04 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001133.1 |  | 0.31 | NRP | taxlllaid A | Xenorhabdus bovienii SS-2004
BGC0000955.1 |  | 0.27 | NRP, Polyketide | althiomycin | Myxococcus xanthus
BGC0001415.1 |  | 0.26 | NRP | althiomycin | Serratia marcescens subsp. marcescens Db11
BGC0001650.1 |  | 0.24 | NRP | Le-pyrrolopyrazines | Lysobacter enzymogenes
BGC0001285.1 |  | 0.18 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP016321.1 - Region 2 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 332,470 - 360,515 nt. (total: 28,046 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.20 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.15 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001441.1 |  | 0.14 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000595.1 |  | 0.13 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  | 0.13 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000597.1 |  | 0.13 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0000892.1 |  | 0.13 | Other | caryoynencin | Burkholderia gladioli BSR3
BGC0001160.1 |  | 0.12 | Polyketide | 1-nonadecene, (14Z)-1,14-nonadecadiene | Synechococcus sp. PCC 7002
BGC0000871.1 |  | 0.12 | Other (Nucleoside) | VEPE, AEPE, TG-1 | Myxococcus xanthus DK 1622
BGC0001768.1 |  | 0.11 | NRP | sansalvamide | [Nectria] haematococca mpVI 77-13-4

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.52 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.45 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001441.1 |  | 0.43 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000595.1 |  | 0.41 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  | 0.41 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000597.1 |  | 0.41 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0000892.1 |  | 0.41 | Other | caryoynencin | Burkholderia gladioli BSR3
BGC0001160.1 |  | 0.40 | Polyketide | 1-nonadecene, (14Z)-1,14-nonadecadiene | Synechococcus sp. PCC 7002
BGC0000871.1 |  | 0.40 | Other (Nucleoside) | VEPE, AEPE, TG-1 | Myxococcus xanthus DK 1622
BGC0001768.1 |  | 0.37 | NRP | sansalvamide | [Nectria] haematococca mpVI 77-13-4

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP016321.1 - Region 3 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 895,817 - 939,409 nt. (total: 43,593 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000837.1 |  | 0.51 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0002008.1 |  | 0.31 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.30 | Other | APE Ec | Escherichia coli CFT073
BGC0001723.1 |  | 0.24 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000231.1 |  | 0.24 | Polyketide | griseusin | Streptomyces griseus
BGC0000228.1 |  | 0.22 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000889.1 |  | 0.22 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0000272.1 |  | 0.21 | Polyketide | spore pigment | Streptomyces collinus
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0002029.1 |  | 0.20 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000837.1 |  | 0.79 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0002008.1 |  | 0.65 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.64 | Other | APE Ec | Escherichia coli CFT073
BGC0001723.1 |  | 0.57 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000231.1 |  | 0.57 | Polyketide | griseusin | Streptomyces griseus
BGC0000228.1 |  | 0.55 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000889.1 |  | 0.55 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0000272.1 |  | 0.54 | Polyketide | spore pigment | Streptomyces collinus
BGC0000248.1 |  | 0.54 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0002029.1 |  | 0.52 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP016322.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,447,468 - 1,492,030 nt. (total: 44,563 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000460.1 |  | 0.80 | NRP | vulnibactin | Vibrio vulnificus CMCP6
BGC0000417.1 |  | 0.24 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001479.1 |  | 0.21 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001833.1 |  | 0.21 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.21 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.21 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001302.1 |  | 0.21 | Other | lomofungin | Streptomyces lomondensis
BGC0001758.1 |  | 0.21 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.21 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001132.1 |  | 0.21 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000460.1 |  | 0.93 | NRP | vulnibactin | Vibrio vulnificus CMCP6
BGC0000417.1 |  | 0.57 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001479.1 |  | 0.54 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001833.1 |  | 0.54 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.54 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.54 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001302.1 |  | 0.54 | Other | lomofungin | Streptomyces lomondensis
BGC0001758.1 |  | 0.53 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.53 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001132.1 |  | 0.53 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names