GCF_030060435.1_ASM3006043v1_genomic - 6 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP125875.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	ectoine	1,240,344	1,250,730	ectoine	Other	66%
Region 1.2	NRPS,arylpolyene	2,130,259	2,199,959	amphi-enterobactin 1 / amphi-enterobactin 2 / amphi-enterobactin 3 / amphi-enterobactin 4	NRP	75%
Region 1.3	betalactone	2,735,135	2,763,420
Region 1.4	RiPP-like	3,149,894	3,160,766

NZ_CP125876.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	RiPP-like	903,933	914,799
Region 2.2	siderophore	1,932,332	1,947,147	vibrioferrin	Other	54%

No secondary metabolite regions were found in these records:: NZ_CP125877.1

Compact view

NZ_CP125875.1 - Region 1 - ectoine

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Location: 1,240,344 - 1,250,730 nt. (total: 10,387 nt) Show pHMM detection rules used

ectoine: ectoine_synt

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000856.1	0.53	Other	ectoine	Methylophaga thalassica
BGC0000859.1	0.52	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.43	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.39	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.37	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.36	Other	ectoine	Methylarcula marina
BGC0000854.1	0.33	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000858.1	0.33	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.33	Other	ectoine	Streptomyces anulatus
BGC0001987.1	0.14	Polyketide	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000856.1	0.80	Other	ectoine	Methylophaga thalassica
BGC0000859.1	0.80	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.74	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.71	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.70	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.69	Other	ectoine	Methylarcula marina
BGC0000854.1	0.67	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000858.1	0.66	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.66	Other	ectoine	Streptomyces anulatus
BGC0001987.1	0.43	Polyketide	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP125875.1 - Region 2 - NRPS,arylpolyene

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Location: 2,130,259 - 2,199,959 nt. (total: 69,701 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
arylpolyene: (APE_KS1 or APE_KS2)

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core biosynthetic genes

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000837.1	0.82	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001890.1	0.56	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0002008.1	0.54	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.51	Other	APE Ec	Escherichia coli CFT073
BGC0001185.1	0.49	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000889.1	0.45	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0000401.1	0.42	NRP	paenibactin	Paenibacillus elgii B69
BGC0001444.1	0.42	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0002029.1	0.41	Other	bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C	Streptomyces lunaelactis
BGC0001592.1	0.41	Other	ferroverdin	Streptomyces lunaelactis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000837.1	0.79	Other	APE Vf	Aliivibrio fischeri ES114
BGC0001890.1	0.73	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001185.1	0.69	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001615.1	0.67	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0002008.1	0.64	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000401.1	0.64	NRP	paenibactin	Paenibacillus elgii B69
BGC0000836.1	0.63	Other	APE Ec	Escherichia coli CFT073
BGC0000236.1	0.60	Polyketide	kinamycin	Streptomyces murayamaensis
BGC0000889.1	0.60	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0001904.1	0.59	Polyketide	fluostatin	Micromonospora rosaria

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 2130258 - 2199959:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 2130258 - 2174206:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1895

Search NORINE for peptide: strict or relaxed

AMP-binding (475..869): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_1897

Search NORINE for peptide: strict or relaxed

AMP-binding (38..445): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg1_1911

Search NORINE for peptide: strict or relaxed

AMP-binding (18..305): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: eVdHLShliK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 50% (weak)

ctg1_1935

Search NORINE for peptide: strict or relaxed

AMP-binding (28..461): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: aLntvGGPLK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

NZ_CP125875.1 - Region 3 - betalactone

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Location: 2,735,135 - 2,763,420 nt. (total: 28,286 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.20	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.15	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.14	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000805.1	0.13	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672
BGC0000597.1	0.13	RiPP	SWA-2138	Streptomyces sp. e14
BGC0000871.1	0.12	Other (Nucleoside)	VEPE, AEPE, TG-1	Myxococcus xanthus DK 1622
BGC0001160.1	0.12	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0000389.1	0.12	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001469.1	0.11	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0000938.1	0.10	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.52	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.45	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.43	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000805.1	0.41	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672
BGC0000597.1	0.41	RiPP	SWA-2138	Streptomyces sp. e14
BGC0000871.1	0.40	Other (Nucleoside)	VEPE, AEPE, TG-1	Myxococcus xanthus DK 1622
BGC0001160.1	0.40	Polyketide	1-nonadecene, (14Z)-1,14-nonadecadiene	Synechococcus sp. PCC 7002
BGC0000389.1	0.40	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001469.1	0.37	NRP	marthiapeptide A	Brevibacillus sp. Leaf182
BGC0000938.1	0.36	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP125875.1 - Region 4 - RiPP-like

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Location: 3,149,894 - 3,160,766 nt. (total: 10,873 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001783.1	0.13	Other	streptonigrin	Streptomyces flocculus
BGC0000207.1	0.13	Polyketide	chartreusin	Streptomyces chartreusis
BGC0001133.1	0.08	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001440.1	0.06	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001480.1	0.05	Other	tundrenone	Methylobacter tundripaludum 21/22

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001783.1	0.42	Other	streptonigrin	Streptomyces flocculus
BGC0000207.1	0.41	Polyketide	chartreusin	Streptomyces chartreusis
BGC0001133.1	0.31	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001440.1	0.25	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001480.1	0.22	Other	tundrenone	Methylobacter tundripaludum 21/22

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP125876.1 - Region 1 - RiPP-like

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Location: 903,933 - 914,799 nt. (total: 10,867 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

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resistance

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KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	RiPP-like	Similarity score	Type	Compound(s)	Organism
BGC0000863.1		0.05	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000934.1		0.03	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0000863.1		0.22	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000934.1		0.15	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP125876.1 - Region 2 - siderophore

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Location: 1,932,332 - 1,947,147 nt. (total: 14,816 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000946.1	0.61	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0000947.1	0.39	Other	vibrioferrin	Vibrio alginolyticus
BGC0001408.1	0.39	Other	xanthoferrin	Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000942.1	0.25	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000943.1	0.19	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0002004.1	0.15	RiPP	methanobactin	Methylosinus trichosporium OB3b
BGC0000694.1	0.08	Saccharide	butirosin	Bacillus circulans
BGC0000693.1	0.08	Saccharide	butirosin A, butirosin B	Bacillus circulans
BGC0000202.1	0.06	Polyketide	azicemicin B	Kibdelosporangium sp. MJ126-NF4
BGC0001690.1	0.06	Polyketide	natamycin	Streptomyces gilvosporeus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000946.1	0.84	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0000947.1	0.71	Other	vibrioferrin	Vibrio alginolyticus
BGC0001408.1	0.71	Other	xanthoferrin	Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000942.1	0.58	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000943.1	0.51	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0002004.1	0.46	RiPP	methanobactin	Methylosinus trichosporium OB3b
BGC0000694.1	0.32	Saccharide	butirosin	Bacillus circulans
BGC0000693.1	0.31	Saccharide	butirosin A, butirosin B	Bacillus circulans
BGC0000202.1	0.24	Polyketide	azicemicin B	Kibdelosporangium sp. MJ126-NF4
BGC0001690.1	0.24	Polyketide	natamycin	Streptomyces gilvosporeus

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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