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Overview
20.1
22.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_FMWL01000008 (original name was: NZ_FMWL01000008.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 20.1 | betalactone | 54,073 | 85,997 |

NZ_FMWL01000004 (original name was: NZ_FMWL01000004.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 22.1 | ranthipeptide | 181,292 | 203,024 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 20.1 | betalactone | 54,073 | 85,997 |
Region 22.1 | ranthipeptide | 181,292 | 203,024 |

No secondary metabolite regions were found in these records:
  NZ_FMWL01000040 (original name was: NZ_FMWL01000040.1)
  NZ_FMWL01000039 (original name was: NZ_FMWL01000039.1)
  NZ_FMWL01000041 (original name was: NZ_FMWL01000041.1)
  NZ_FMWL01000037 (original name was: NZ_FMWL01000037.1)
  NZ_FMWL01000036 (original name was: NZ_FMWL01000036.1)
  NZ_FMWL01000035 (original name was: NZ_FMWL01000035.1)
  NZ_FMWL01000034 (original name was: NZ_FMWL01000034.1)
  NZ_FMWL01000030 (original name was: NZ_FMWL01000030.1)
  NZ_FMWL01000029 (original name was: NZ_FMWL01000029.1)
  NZ_FMWL01000028 (original name was: NZ_FMWL01000028.1)
  NZ_FMWL01000027 (original name was: NZ_FMWL01000027.1)
  NZ_FMWL01000038 (original name was: NZ_FMWL01000038.1)
  NZ_FMWL01000026 (original name was: NZ_FMWL01000026.1)
  NZ_FMWL01000025 (original name was: NZ_FMWL01000025.1)
  NZ_FMWL01000024 (original name was: NZ_FMWL01000024.1)
  NZ_FMWL01000023 (original name was: NZ_FMWL01000023.1)
  NZ_FMWL01000012 (original name was: NZ_FMWL01000012.1)
  NZ_FMWL01000009 (original name was: NZ_FMWL01000009.1)
  NZ_FMWL01000001 (original name was: NZ_FMWL01000001.1)
  NZ_FMWL01000013 (original name was: NZ_FMWL01000013.1)
  NZ_FMWL01000003 (original name was: NZ_FMWL01000003.1)
  NZ_FMWL01000017 (original name was: NZ_FMWL01000017.1)
  NZ_FMWL01000002 (original name was: NZ_FMWL01000002.1)
  NZ_FMWL01000010 (original name was: NZ_FMWL01000010.1)
  NZ_FMWL01000007 (original name was: NZ_FMWL01000007.1)
  NZ_FMWL01000011 (original name was: NZ_FMWL01000011.1)
  NZ_FMWL01000031 (original name was: NZ_FMWL01000031.1)
  NZ_FMWL01000014 (original name was: NZ_FMWL01000014.1)
  NZ_FMWL01000032 (original name was: NZ_FMWL01000032.1)
  NZ_FMWL01000022 (original name was: NZ_FMWL01000022.1)
  NZ_FMWL01000015 (original name was: NZ_FMWL01000015.1)
  NZ_FMWL01000033 (original name was: NZ_FMWL01000033.1)
  NZ_FMWL01000006 (original name was: NZ_FMWL01000006.1)
  NZ_FMWL01000016 (original name was: NZ_FMWL01000016.1)
  NZ_FMWL01000021 (original name was: NZ_FMWL01000021.1)
  NZ_FMWL01000018 (original name was: NZ_FMWL01000018.1)
  NZ_FMWL01000005 (original name was: NZ_FMWL01000005.1)
  NZ_FMWL01000019 (original name was: NZ_FMWL01000019.1)
  NZ_FMWL01000020 (original name was: NZ_FMWL01000020.1)

Compact view
c00020_NZ_FMWL.. - Region 1 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 54,073 - 85,997 nt. (total: 31,925 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.20 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000851.1 |  | 0.19 | Other | albonoursin | Streptomyces noursei ATCC 11455
BGC0000889.1 |  | 0.17 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0000904.1 |  | 0.16 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0002029.1 |  | 0.16 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.16 | Other | ferroverdin | Streptomyces lunaelactis
BGC0000698.1 |  | 0.15 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0000703.1 |  | 0.15 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000466.1 |  | 0.14 | NRP | yatakemycin | Streptomyces sp. TP-A2060
BGC0001607.1 |  | 0.14 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.52 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000851.1 |  | 0.51 | Other | albonoursin | Streptomyces noursei ATCC 11455
BGC0000889.1 |  | 0.49 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0000904.1 |  | 0.47 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0002029.1 |  | 0.47 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.47 | Other | ferroverdin | Streptomyces lunaelactis
BGC0000698.1 |  | 0.46 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0000703.1 |  | 0.45 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000466.1 |  | 0.44 | NRP | yatakemycin | Streptomyces sp. TP-A2060
BGC0001607.1 |  | 0.44 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00022_NZ_FMWL.. - Region 1 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 181,292 - 203,024 nt. (total: 21,733 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.18 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.18 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001887.1 |  | 0.13 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000695.1 |  | 0.10 | Saccharide | fortimicin | Micromonospora olivasterospora
BGC0000807.1 |  | 0.10 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0001591.1 |  | 0.05 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.05 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000027.1 |  | 0.05 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0001603.1 |  | 0.04 | Saccharide | gentamicin | Micromonospora echinospora
BGC0000714.1 |  | 0.04 | Saccharide | sisomicin | Micromonospora inyonensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.50 | Other | nucleocidin | Streptomyces calvus
BGC0000599.1 |  | 0.50 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001887.1 |  | 0.42 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000695.1 |  | 0.35 | Saccharide | fortimicin | Micromonospora olivasterospora
BGC0000807.1 |  | 0.35 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0001591.1 |  | 0.23 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.23 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000027.1 |  | 0.22 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0001603.1 |  | 0.19 | Saccharide | gentamicin | Micromonospora echinospora
BGC0000714.1 |  | 0.19 | Saccharide | sisomicin | Micromonospora inyonensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names