GCF_008693705.1_ASM869370v1_genomic - 4 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP044060.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	194,327	238,307	amphi-enterobactin 1 / amphi-enterobactin 2 / amphi-enterobactin 3 / amphi-enterobactin 4	NRP	12%
Region 1.2	RiPP-like	338,792	348,761
Region 1.3	RiPP-like	1,977,696	1,988,544
Region 1.4	hserlactone	2,500,549	2,521,199

No secondary metabolite regions were found in these records:: NZ_CP044061.1

Compact view

NZ_CP044060.1 - Region 1 - NRPS

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Location: 194,327 - 238,307 nt. (total: 43,981 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.34	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.27	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001149.1	0.26	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001302.1	0.25	Other	lomofungin	Streptomyces lomondensis
BGC0001131.1	0.25	NRP	ambactin	Xenorhabdus miraniensis
BGC0000401.1	0.24	NRP	paenibactin	Paenibacillus elgii B69
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000410.1	0.24	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001535.1	0.24	Other	branched-chain fatty acids	Streptomyces filamentosus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.67	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.60	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001149.1	0.59	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001302.1	0.58	Other	lomofungin	Streptomyces lomondensis
BGC0001131.1	0.58	NRP	ambactin	Xenorhabdus miraniensis
BGC0000401.1	0.58	NRP	paenibactin	Paenibacillus elgii B69
BGC0001833.1	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000410.1	0.57	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001132.1	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001535.1	0.57	Other	branched-chain fatty acids	Streptomyces filamentosus

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 194326 - 238307:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_178

Search NORINE for peptide: strict or relaxed

AMP-binding (33..450): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg1_181

Search NORINE for peptide: strict or relaxed

AMP-binding (473..870): ser

NRPSPredictor2: ser

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

NZ_CP044060.1 - Region 2 - RiPP-like

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Location: 338,792 - 348,761 nt. (total: 9,970 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000703.1	0.15	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0001184.1	0.07	Other	bacilysin	Bacillus velezensis FZB42
BGC0000934.1	0.05	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0000893.1	0.04	NRP	chloramphenicol	Streptomyces venezuelae ATCC 10712

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000703.1	0.45	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0001184.1	0.29	Other	bacilysin	Bacillus velezensis FZB42
BGC0000934.1	0.22	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0000893.1	0.18	NRP	chloramphenicol	Streptomyces venezuelae ATCC 10712

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP044060.1 - Region 3 - RiPP-like

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Location: 1,977,696 - 1,988,544 nt. (total: 10,849 nt) Show pHMM detection rules used

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

No matches found.

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP044060.1 - Region 4 - hserlactone

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Location: 2,500,549 - 2,521,199 nt. (total: 20,651 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000506.1	0.09	RiPP	entianin	Bacillus subtilis subsp. spizizenii
BGC0000934.1	0.09	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0001791.1	0.06	NRP	sunshinamide	Gynuella sunshinyii YC6258
BGC0001480.1	0.06	Other	tundrenone	Methylobacter tundripaludum 21/22
BGC0001053.1	0.05	NRP, Polyketide	tubulysin A	Archangium disciforme
BGC0002010.1	0.05	NRP, Polyketide	streptophenazine B, streptophenazine C, streptophenazine F, streptophenazine G, streptophenazine H	Streptomyces sp. CNB091
BGC0001133.1	0.05	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001196.1	0.05	NRP	desotamide	Streptomyces scopuliridis
BGC0000961.1	0.05	NRP, Polyketide	bactobolin	Burkholderia thailandensis E264
BGC0001675.1	0.05	Polyketide	murayaquinone	Streptomyces griseoruber

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000506.1	0.34	RiPP	entianin	Bacillus subtilis subsp. spizizenii
BGC0000934.1	0.32	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0001791.1	0.26	NRP	sunshinamide	Gynuella sunshinyii YC6258
BGC0001480.1	0.26	Other	tundrenone	Methylobacter tundripaludum 21/22
BGC0001053.1	0.23	NRP, Polyketide	tubulysin A	Archangium disciforme
BGC0002010.1	0.23	NRP, Polyketide	streptophenazine B, streptophenazine C, streptophenazine F, streptophenazine G, streptophenazine H	Streptomyces sp. CNB091
BGC0001133.1	0.23	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001196.1	0.22	NRP	desotamide	Streptomyces scopuliridis
BGC0000961.1	0.22	NRP, Polyketide	bactobolin	Burkholderia thailandensis E264
BGC0001675.1	0.22	Polyketide	murayaquinone	Streptomyces griseoruber

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names