GCF_016127195.1_ASM1612719v1_genomic - 4 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP066092.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	701,375	745,364	amphi-enterobactin 1 / amphi-enterobactin 2 / amphi-enterobactin 3 / amphi-enterobactin 4	NRP	12%
Region 2	hserlactone	2,964,666	2,985,304
Region 3	arylpolyene	3,196,708	3,240,289	aryl polyenes	Other	55%
Region 4	RiPP-like	3,997,891	4,008,748

NZ_CP066092.1 - Region 1 - NRPS

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Location: 701,375 - 745,364 nt. (total: 43,990 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.34	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.27	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001149.1	0.26	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0000410.1	0.25	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001302.1	0.25	Other	lomofungin	Streptomyces lomondensis
BGC0001131.1	0.25	NRP	ambactin	Xenorhabdus miraniensis
BGC0000401.1	0.24	NRP	paenibactin	Paenibacillus elgii B69
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001535.1	0.24	Other	branched-chain fatty acids	Streptomyces filamentosus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.67	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.60	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001149.1	0.59	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0000410.1	0.59	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001302.1	0.58	Other	lomofungin	Streptomyces lomondensis
BGC0001131.1	0.58	NRP	ambactin	Xenorhabdus miraniensis
BGC0000401.1	0.58	NRP	paenibactin	Paenibacillus elgii B69
BGC0001833.1	0.57	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.1	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001535.1	0.57	Other	branched-chain fatty acids	Streptomyces filamentosus

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 701374 - 745364:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_626

Search NORINE for peptide: strict or relaxed

AMP-binding (476..873): ser

NRPSPredictor2: ser

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_629

Search NORINE for peptide: strict or relaxed

AMP-binding (33..452): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

NZ_CP066092.1 - Region 2 - hserlactone

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Location: 2,964,666 - 2,985,304 nt. (total: 20,639 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000506.1	0.10	RiPP	entianin	Bacillus subtilis subsp. spizizenii
BGC0000934.1	0.09	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0001791.1	0.06	NRP	sunshinamide	Gynuella sunshinyii YC6258
BGC0002010.1	0.05	NRP, Polyketide	streptophenazine B, streptophenazine C, streptophenazine F, streptophenazine G, streptophenazine H	Streptomyces sp. CNB091
BGC0001133.1	0.05	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001196.1	0.05	NRP	desotamide	Streptomyces scopuliridis
BGC0001675.1	0.05	Polyketide	murayaquinone	Streptomyces griseoruber
BGC0001106.1	0.05	NRP, Polyketide	oxalomycin B	Streptomyces albus
BGC0000376.1	0.05	NRP	JBIR-34, JBIR-35	Streptomyces sp. Sp080513GE-23
BGC0001619.1	0.03	Polyketide	ibomycin	Streptomyces sp. WAC2288

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000506.1	0.35	RiPP	entianin	Bacillus subtilis subsp. spizizenii
BGC0000934.1	0.32	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0001791.1	0.26	NRP	sunshinamide	Gynuella sunshinyii YC6258
BGC0002010.1	0.23	NRP, Polyketide	streptophenazine B, streptophenazine C, streptophenazine F, streptophenazine G, streptophenazine H	Streptomyces sp. CNB091
BGC0001133.1	0.23	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001196.1	0.22	NRP	desotamide	Streptomyces scopuliridis
BGC0001675.1	0.22	Polyketide	murayaquinone	Streptomyces griseoruber
BGC0001106.1	0.22	NRP, Polyketide	oxalomycin B	Streptomyces albus
BGC0000376.1	0.21	NRP	JBIR-34, JBIR-35	Streptomyces sp. Sp080513GE-23
BGC0001619.1	0.15	Polyketide	ibomycin	Streptomyces sp. WAC2288

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP066092.1 - Region 3 - arylpolyene

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Location: 3,196,708 - 3,240,289 nt. (total: 43,582 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.39	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000837.1	0.36	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000836.1	0.31	Other	APE Ec	Escherichia coli CFT073
BGC0000234.1	0.23	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000272.1	0.21	Polyketide	spore pigment	Streptomyces collinus
BGC0001895.1	0.21	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0000248.1	0.21	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000261.1	0.21	Polyketide	R1128	Streptomyces sp. R1128
BGC0002000.1	0.21	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0000375.1	0.20	NRP	indigoidine	Streptomyces chromofuscus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.71	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000837.1	0.69	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000836.1	0.65	Other	APE Ec	Escherichia coli CFT073
BGC0000234.1	0.56	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000272.1	0.54	Polyketide	spore pigment	Streptomyces collinus
BGC0001895.1	0.54	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0000248.1	0.54	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000261.1	0.53	Polyketide	R1128	Streptomyces sp. R1128
BGC0002000.1	0.53	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0000375.1	0.53	NRP	indigoidine	Streptomyces chromofuscus

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP066092.1 - Region 4 - RiPP-like

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Location: 3,997,891 - 4,008,748 nt. (total: 10,858 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.10	Other	bacilysin	Bacillus velezensis FZB42
BGC0000934.1	0.07	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0000893.1	0.05	NRP	chloramphenicol	Streptomyces venezuelae ATCC 10712
BGC0001436.1	0.05	Polyketide	cornexistin	Paecilomyces divaricatus
BGC0001557.1	0.05	Polyketide	cornexistin	Paecilomyces divaricatus
BGC0002010.1	0.04	NRP, Polyketide	streptophenazine B, streptophenazine C, streptophenazine F, streptophenazine G, streptophenazine H	Streptomyces sp. CNB091
BGC0000814.1	0.04	Alkaloid	K-252a	Nonomuraea longicatena
BGC0000953.1	0.04	Saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0001732.1	0.03	Other	paulomycin	Streptomyces sp. YN86

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.35	Other	bacilysin	Bacillus velezensis FZB42
BGC0000934.1	0.28	Other (Phenazine)	5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G	Kitasatospora sp. HKI 714
BGC0000893.1	0.22	NRP	chloramphenicol	Streptomyces venezuelae ATCC 10712
BGC0001436.1	0.21	Polyketide	cornexistin	Paecilomyces divaricatus
BGC0001557.1	0.21	Polyketide	cornexistin	Paecilomyces divaricatus
BGC0002010.1	0.18	NRP, Polyketide	streptophenazine B, streptophenazine C, streptophenazine F, streptophenazine G, streptophenazine H	Streptomyces sp. CNB091
BGC0000814.1	0.17	Alkaloid	K-252a	Nonomuraea longicatena
BGC0000953.1	0.17	Saccharide	amicetin	Streptomyces vinaceusdrappus
BGC0001732.1	0.15	Other	paulomycin	Streptomyces sp. YN86

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names