LOCUS       NC_021016.1            19327 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021016.1 Anaerostipes hadrus, complete sequence.
ACCESSION   NC_021016
VERSION     NC_021016.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:21:46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1632020
            Orig. end    :: 1651347
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..783
                     /locus_tag="ctg1_1618"
                     /transl_table=11
                     /translation="MKKNLVVIEELKKQGKALLDARRDNFVRQSLLSDEFLNFMQQNKK
                     PFDLLMSYYECAIMEVETKFRVLNHELSLEYDNNPIESIKTRVKSYDSILKKIRRKNIP
                     LNLRAIEDNLKDIAGVRVICSFPDDIYKLAESFLKQDDITLIERKDYIKNPKPSGYRSL
                     HLIVQVPIFLQNEKKMVNVEVQFRTIAMDFWASLDHKMRYKKELSDEEVEILQEELYDC
                     ARQSAVLDERMQGIRDRITKKQEQETILLEDKNSKDWL"
     protocluster    1..19327
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1641886:1642156](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9867..10136
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..19327
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19327
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     PFAM_domain     256..618
                     /aSDomain="RelA_SpoT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04607.19"
                     /description="Region found in RelA / SpoT proteins"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1618_0001"
                     /evalue="8.50E-35"
                     /label="ctg1_1618"
                     /locus_tag="ctg1_1618"
                     /protein_end="206"
                     /protein_start="85"
                     /score="119.7"
                     /tool="antismash"
                     /translation="TRVKSYDSILKKIRRKNIPLNLRAIEDNLKDIAGVRVICSFPDDI
                     YKLAESFLKQDDITLIERKDYIKNPKPSGYRSLHLIVQVPIFLQNEKKMVNVEVQFRTI
                     AMDFWASLDHKMRYKKE"
     CDS             967..2910
                     /locus_tag="ctg1_1619"
                     /transl_table=11
                     /translation="LIRRQIELLKLLSKQREYKPASFFSKSLDVSTKTIYTDITYLQSE
                     VEKYKVDLVRAPRIGIRLEGEKENIQHMLRDLQKDNLSEDEKYTPEYRRLWILKKVLID
                     CEIITLESVSKEFLVSKTSLYQDIAVINKSIESQSDVKLEVGECGICILGEESEIQNAV
                     NNYLLSESKEEMFSDFTHKLGNFFELDVIKAVSDLILNDFEELTEVLSEYYLKSLLVTL
                     IMQSSRLLKKKHMNEETEISYNNIRHMETYIVANSIAEQLKYQLHITYSNNDMEYLCRQ
                     LYAHRVTHHVKHMRTDYEETVRDVIKRMSEIQKLDLTRDKKLYESLLYHLPPMILRLQN
                     NIQIVNPMLDNIKQEYPELFTTMWYALTQIELRYQVTLTEDEVSLILLHFQVALDQFEQ
                     VGNIVVVCTYGVSSSQLILSRVKQILPAKDNITVTNTKKLKEIDLSKVDLIISSVDIED
                     PEISYVKVNPLLTKDDYANILDAYTKQVLLIKNNVCDNQKNGIKAPTLKKYLEGKFIFL
                     KQDLDSKEKCLDFIIDVLEKDNAVYDEFREAIYKREKLGVTCLDTGVALPHADPQTIKK
                     SRIILLTLKHPVDWGGTLVSLIVVTAFPEEEMNQIRDVINELYQLIGEKEDVNTFIRFE
                     TIQEVLKVFHES"
     PFAM_domain     976..1146
                     /aSDomain="HTH_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08279.14"
                     /description="HTH domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1619_0002"
                     /evalue="1.90E-06"
                     /label="ctg1_1619"
                     /locus_tag="ctg1_1619"
                     /protein_end="60"
                     /protein_start="3"
                     /score="27.8"
                     /tool="antismash"
                     /translation="RQIELLKLLSKQREYKPASFFSKSLDVSTKTIYTDITYLQSEVEK
                     YKVDLVRAPRIG"
     PFAM_domain     1876..2139
                     /aSDomain="PRD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00874.22"
                     /description="PRD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1619_0003"
                     /evalue="2.60E-20"
                     /label="ctg1_1619"
                     /locus_tag="ctg1_1619"
                     /protein_end="391"
                     /protein_start="303"
                     /score="72.6"
                     /tool="antismash"
                     /translation="DVIKRMSEIQKLDLTRDKKLYESLLYHLPPMILRLQNNIQIVNPM
                     LDNIKQEYPELFTTMWYALTQIELRYQVTLTEDEVSLILLHFQ"
     PFAM_domain     2170..2403
                     /aSDomain="PTS_IIB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02302.19"
                     /description="PTS system, Lactose/Cellobiose specific IIB
                     subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1619_0004"
                     /evalue="1.10E-05"
                     /label="ctg1_1619"
                     /locus_tag="ctg1_1619"
                     /protein_end="479"
                     /protein_start="401"
                     /score="26.1"
                     /tool="antismash"
                     /translation="NIVVVCTYGVSSSQLILSRVKQILPAKDNITVTNTKKLKEIDLSK
                     VDLIISSVDIEDPEISYVKVNPLLTKDDYANIL"
     PFAM_domain     2491..2901
                     /aSDomain="PTS_EIIA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00359.24"
                     /description="Phosphoenolpyruvate-dependent sugar
                     phosphotransferase system, EIIA 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1619_0005"
                     /evalue="2.20E-29"
                     /label="ctg1_1619"
                     /locus_tag="ctg1_1619"
                     /protein_end="645"
                     /protein_start="508"
                     /score="102.3"
                     /tool="antismash"
                     /translation="YLEGKFIFLKQDLDSKEKCLDFIIDVLEKDNAVYDEFREAIYKRE
                     KLGVTCLDTGVALPHADPQTIKKSRIILLTLKHPVDWGGTLVSLIVVTAFPEEEMNQIR
                     DVINELYQLIGEKEDVNTFIRFETIQEVLKVFH"
     CDS             2929..3384
                     /locus_tag="ctg1_1620"
                     /transl_table=11
                     /translation="MYFDQRLCFFHQKVESQDQLFQMMTDKMLEAGCVKENYYEGISNR
                     EKEYPTGLLVNQTGFAIPHTDSERVNKSQICFLSLDEPIEFEDMVDKSHKISVELVFML
                     AMAQPHEQVNTLQNLIALFQDDEKVAKLKECNTEKELMQILNASGIE"
     PFAM_domain     2932..3366
                     /aSDomain="PTS_EIIA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00359.24"
                     /description="Phosphoenolpyruvate-dependent sugar
                     phosphotransferase system, EIIA 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1620_0006"
                     /evalue="1.50E-35"
                     /label="ctg1_1620"
                     /locus_tag="ctg1_1620"
                     /protein_end="146"
                     /protein_start="1"
                     /score="122.3"
                     /tool="antismash"
                     /translation="YFDQRLCFFHQKVESQDQLFQMMTDKMLEAGCVKENYYEGISNRE
                     KEYPTGLLVNQTGFAIPHTDSERVNKSQICFLSLDEPIEFEDMVDKSHKISVELVFMLA
                     MAQPHEQVNTLQNLIALFQDDEKVAKLKECNTEKELMQILN"
     CDS             3410..4738
                     /locus_tag="ctg1_1621"
                     /transl_table=11
                     /translation="MLSVLQWFIGLGSTVFLPIIIFILGIIFGVKPAKAAISGFTVGIG
                     SIGLNLVIGLLSDNLGTAIQVMGEHYGFSLNIMDIGCGVGGPLAFSTTFGIILIPMSLI
                     VNLLFVMLGWTKTLNVDIWNFWFPCFLGLVAQAVTGNFVTGILGALVAVMLQWLLADIF
                     QKKVSEFFGYPGIAISHMMALSGALIAVPLNWIFDRIPGFNKIEADSETIAKRFGFFGD
                     TVVIGIIIGMIVGFLAKYDFAKAAQLGMATGAVMKIMPKMVAMFMEGLMPIAEAAKEFA
                     NKRLGGRSVNIGMDAALTVGHSTVMSTNLLMVPISLALAIILPGNQTLPFGDLAFYAFG
                     ICLMIPIFRGNVVRSIVGCSIYMVSMLYLSTWLAPIITNVFKIAHYNVGTSGQVTSVLC
                     GIWPAGLFAVATKSLGNIGLAVIGVVVIALLVYVNKIRAQKEN"
     PFAM_domain     3431..4555
                     /aSDomain="EIIC-GAT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03611.16"
                     /description="PTS system sugar-specific permease component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1621_0007"
                     /evalue="1.40E-63"
                     /label="ctg1_1621"
                     /locus_tag="ctg1_1621"
                     /protein_end="382"
                     /protein_start="7"
                     /score="215.4"
                     /tool="antismash"
                     /translation="FIGLGSTVFLPIIIFILGIIFGVKPAKAAISGFTVGIGSIGLNLV
                     IGLLSDNLGTAIQVMGEHYGFSLNIMDIGCGVGGPLAFSTTFGIILIPMSLIVNLLFVM
                     LGWTKTLNVDIWNFWFPCFLGLVAQAVTGNFVTGILGALVAVMLQWLLADIFQKKVSEF
                     FGYPGIAISHMMALSGALIAVPLNWIFDRIPGFNKIEADSETIAKRFGFFGDTVVIGII
                     IGMIVGFLAKYDFAKAAQLGMATGAVMKIMPKMVAMFMEGLMPIAEAAKEFANKRLGGR
                     SVNIGMDAALTVGHSTVMSTNLLMVPISLALAIILPGNQTLPFGDLAFYAFGICLMIPI
                     FRGNVVRSIVGCSIYMVSMLYLSTWLAPIITNVFK"
     CDS             4778..5062
                     /locus_tag="ctg1_1622"
                     /transl_table=11
                     /translation="MKKLLIVCGAGHATSTIAVAKVSAWLEKEGYSDKVKIYQSKIADE
                     LNKIDDYDAVISTTIVPDSIKDKVIQGLPLLNGMGVDQVYDQLKTRLGL"
     PFAM_domain     4784..5032
                     /aSDomain="PTS_IIB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02302.19"
                     /description="PTS system, Lactose/Cellobiose specific IIB
                     subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1622_0008"
                     /evalue="4.40E-09"
                     /label="ctg1_1622"
                     /locus_tag="ctg1_1622"
                     /protein_end="85"
                     /protein_start="2"
                     /score="37.0"
                     /tool="antismash"
                     /translation="KLLIVCGAGHATSTIAVAKVSAWLEKEGYSDKVKIYQSKIADELN
                     KIDDYDAVISTTIVPDSIKDKVIQGLPLLNGMGVDQVY"
     CDS             5072..5587
                     /locus_tag="ctg1_1623"
                     /transl_table=11
                     /translation="MGVFFGEVTLETVKGRASYHDISDEIRENIKKSELKNGCVVISSA
                     HTTCSLYFDECMHDTNYWGDEYLQADINDVMEKIAPSMKMENQYHSPGPKHIEFGLSLG
                     SKDYPAEKWTMLNTDAHLKSSIFGSPSLTFIVKDGEIQLGALGKVYFVDWDQLRERTRK
                     VQIMVMGE"
     PFAM_domain     5132..5569
                     /aSDomain="UPF0047"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01894.19"
                     /description="Uncharacterised protein family UPF0047"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1623_0009"
                     /evalue="9.10E-30"
                     /label="ctg1_1623"
                     /locus_tag="ctg1_1623"
                     /protein_end="166"
                     /protein_start="20"
                     /score="103.3"
                     /tool="antismash"
                     /translation="DISDEIRENIKKSELKNGCVVISSAHTTCSLYFDECMHDTNYWGD
                     EYLQADINDVMEKIAPSMKMENQYHSPGPKHIEFGLSLGSKDYPAEKWTMLNTDAHLKS
                     SIFGSPSLTFIVKDGEIQLGALGKVYFVDWDQLRERTRKVQI"
     CDS             5590..6246
                     /locus_tag="ctg1_1624"
                     /transl_table=11
                     /translation="MKIISPSLLNSDTYQIKEQFEALEKCGINYIHIDITDGHFVPMIS
                     FGANTVKDLRKHTDFVLDCHLMVENPENLIPVIADAGADIITVHTEATKHIYRSIQTIK
                     KCGKKAGIAINPGTPVSMIKEILPMADLVLCMTTNPGVFGESFIPSVADKVKNLCELRE
                     QKGYSYQIQVDGSINDQTAIVCKKAGADIFVSGSYIFGGNIEERIHKIMDAGEEM"
     PFAM_domain     5599..6189
                     /aSDomain="Ribul_P_3_epim"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00834.21"
                     /description="Ribulose-phosphate 3 epimerase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1624_0010"
                     /evalue="4.00E-66"
                     /label="ctg1_1624"
                     /locus_tag="ctg1_1624"
                     /protein_end="200"
                     /protein_start="3"
                     /score="222.3"
                     /tool="antismash"
                     /translation="ISPSLLNSDTYQIKEQFEALEKCGINYIHIDITDGHFVPMISFGA
                     NTVKDLRKHTDFVLDCHLMVENPENLIPVIADAGADIITVHTEATKHIYRSIQTIKKCG
                     KKAGIAINPGTPVSMIKEILPMADLVLCMTTNPGVFGESFIPSVADKVKNLCELREQKG
                     YSYQIQVDGSINDQTAIVCKKAGADIFVSGSYIF"
     aSDomain        5599..6222
                     /aSDomain="TIGR01163"
                     /aSTool="tigrfam"
                     /description="rpe: ribulose-phosphate 3-epimerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1624_0001"
                     /evalue="5.60E-72"
                     /identifier="TIGR01163"
                     /label="ctg1_1624"
                     /locus_tag="ctg1_1624"
                     /protein_end="211"
                     /protein_start="3"
                     /score="239.5"
                     /tool="antismash"
                     /translation="ISPSLLNSDTYQIKEQFEALEKCGINYIHIDITDGHFVPMISFGA
                     NTVKDLRKHTDFVLDCHLMVENPENLIPVIADAGADIITVHTEATKHIYRSIQTIKKCG
                     KKAGIAINPGTPVSMIKEILPMADLVLCMTTNPGVFGESFIPSVADKVKNLCELREQKG
                     YSYQIQVDGSINDQTAIVCKKAGADIFVSGSYIFGGNIEERIHKI"
     CDS             6243..6797
                     /locus_tag="ctg1_1625"
                     /transl_table=11
                     /translation="VKVKENLEHILKELQDATFKIEEEQIENVLKLIAPDKKIFLTGKG
                     RSGLAAKGFANRLMHLGFQAYVIGEISTPHTKAGDLLIITSGSGETDALVSIAKKAKES
                     GLYLGLVTMNPQSTLGKMADGMIILPGDSKGNNEEKHSIQPMGSQFEQMSFLIFDAIVL
                     KLMENWNQTSEQMFMRHADLE"
     aSDomain        6264..6794
                     /aSDomain="TIGR03127"
                     /aSTool="tigrfam"
                     /description="RuMP_HxlB: 6-phospho 3-hexuloisomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1625_0002"
                     /evalue="1.60E-60"
                     /identifier="TIGR03127"
                     /label="ctg1_1625"
                     /locus_tag="ctg1_1625"
                     /protein_end="184"
                     /protein_start="7"
                     /score="202.0"
                     /tool="antismash"
                     /translation="EHILKELQDATFKIEEEQIENVLKLIAPDKKIFLTGKGRSGLAAK
                     GFANRLMHLGFQAYVIGEISTPHTKAGDLLIITSGSGETDALVSIAKKAKESGLYLGLV
                     TMNPQSTLGKMADGMIILPGDSKGNNEEKHSIQPMGSQFEQMSFLIFDAIVLKLMENWN
                     QTSEQMFMRHADLE"
     PFAM_domain     6339..6638
                     /aSDomain="SIS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01380.24"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1625_0011"
                     /evalue="2.40E-12"
                     /label="ctg1_1625"
                     /locus_tag="ctg1_1625"
                     /protein_end="132"
                     /protein_start="32"
                     /score="46.9"
                     /tool="antismash"
                     /translation="IAPDKKIFLTGKGRSGLAAKGFANRLMHLGFQAYVIGEISTPHTK
                     AGDLLIITSGSGETDALVSIAKKAKESGLYLGLVTMNPQSTLGKMADGMIILPGD"
     CDS             7009..8370
                     /locus_tag="ctg1_1626"
                     /transl_table=11
                     /translation="MNIIIVGCGRIGSTLVEELSGENHDISIIDEKAHVVQKLAETHDV
                     LGVIGNGASYSILSDAGVETADIIIAVTNSDELNLLCCLIAKKAGRCETVARVRNPVYY
                     DEISFIKEEMGISVVLNPELSAAYEIARLLRFPSAMEVNKFSKGRIEMLKYRIPHNSKL
                     DGMTLIDVSNQLNCEILISAVERKKELIIPNGSFQLREKDIISFVGRPNCAMEFFRKIG
                     ERKNQVHEAMIIGGSKIGFYLSKLLVSSGIGVKLIDKDRDQCERLNESIPDAMIIHGNG
                     NDHDMLLEEGLTDVDAFIALTNHDEENMFLSLYAQSQSDAKLVTKVQKLNYDAMIERLD
                     LGSMIYPEYLTAQYIIQYVRARQNSIGSNIENLYKLMDGRAEALEFHIQKGSPVIGRPI
                     KDLSLIDNLLICSIYRKGKPMIPNGQDHMEEDDLVVVVTTKKGLHDVKDILKRG"
     PFAM_domain     7015..7374
                     /aSDomain="TrkA_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02254.20"
                     /description="TrkA-N domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1626_0012"
                     /evalue="6.10E-26"
                     /label="ctg1_1626"
                     /locus_tag="ctg1_1626"
                     /protein_end="122"
                     /protein_start="2"
                     /score="91.0"
                     /tool="antismash"
                     /translation="IIIVGCGRIGSTLVEELSGENHDISIIDEKAHVVQKLAETHDVLG
                     VIGNGASYSILSDAGVETADIIIAVTNSDELNLLCCLIAKKAGRCETVARVRNPVYYDE
                     ISFIKEEMGISVVLNP"
     PFAM_domain     7471..7671
                     /aSDomain="TrkA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02080.23"
                     /description="TrkA-C domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1626_0013"
                     /evalue="9.80E-10"
                     /label="ctg1_1626"
                     /locus_tag="ctg1_1626"
                     /protein_end="221"
                     /protein_start="154"
                     /score="38.3"
                     /tool="antismash"
                     /translation="YRIPHNSKLDGMTLIDVSNQLNCEILISAVERKKELIIPNGSFQL
                     REKDIISFVGRPNCAMEFFRKI"
     PFAM_domain     7702..8049
                     /aSDomain="TrkA_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02254.20"
                     /description="TrkA-N domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1626_0014"
                     /evalue="4.40E-20"
                     /label="ctg1_1626"
                     /locus_tag="ctg1_1626"
                     /protein_end="347"
                     /protein_start="231"
                     /score="72.2"
                     /tool="antismash"
                     /translation="MIIGGSKIGFYLSKLLVSSGIGVKLIDKDRDQCERLNESIPDAMI
                     IHGNGNDHDMLLEEGLTDVDAFIALTNHDEENMFLSLYAQSQSDAKLVTKVQKLNYDAM
                     IERLDLGSMIYP"
     PFAM_domain     8161..8358
                     /aSDomain="TrkA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02080.23"
                     /description="TrkA-C domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1626_0015"
                     /evalue="5.90E-13"
                     /label="ctg1_1626"
                     /locus_tag="ctg1_1626"
                     /protein_end="450"
                     /protein_start="384"
                     /score="48.6"
                     /tool="antismash"
                     /translation="EFHIQKGSPVIGRPIKDLSLIDNLLICSIYRKGKPMIPNGQDHME
                     EDDLVVVVTTKKGLHDVKDIL"
     CDS             8386..9870
                     /locus_tag="ctg1_1627"
                     /transl_table=11
                     /translation="MNFSMIRYVIGLVMLFESAFLSLPCLIALIYHEKKGFSFWIMLFV
                     CLIIGILFVMKKPKKTVYYAKEGFLTVAISWIVMSFFGALPFVINGDIPSVVDAMFETV
                     SGFTTTGSSILTDVEALARCSLFWRSFTHWVGGMGVFVFVLAVMPLVGGQNIHLMRAES
                     PGPSVGKLVPKIRKTSMILYKIYIFMTIVMVVLLLLGKLPLFDSLLLAFGTAGTGGFSI
                     LNSGCASYSPYIQYLIAIFMILFGVNFNVYYFILIKKFKDAIHYEELKYYLLFIGASVA
                     MITYNIHSLFPTIEQAFRHALFQVGTVITTTGYASTDFNKWPEFSKFILVMLMFSGACA
                     GSTGGGMKVSRLVIMLKTVKKELLSYLHPRTVRKVKFNGRIVEHEVIRGINVYMIAYAF
                     VLMFSVLIISIDNFDFTSNFTAVVATLNNIGPGLNIVGPTGNFSMYSNLSKIVMIFDML
                     AGRLELFPMLLLINPYTWKEIKIRKNKKNKKEGHSI"
     PFAM_domain     8500..9795
                     /aSDomain="TrkH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02386.18"
                     /description="Cation transport protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1627_0016"
                     /evalue="9.50E-52"
                     /label="ctg1_1627"
                     /locus_tag="ctg1_1627"
                     /protein_end="470"
                     /protein_start="38"
                     /score="176.2"
                     /tool="antismash"
                     /translation="FWIMLFVCLIIGILFVMKKPKKTVYYAKEGFLTVAISWIVMSFFG
                     ALPFVINGDIPSVVDAMFETVSGFTTTGSSILTDVEALARCSLFWRSFTHWVGGMGVFV
                     FVLAVMPLVGGQNIHLMRAESPGPSVGKLVPKIRKTSMILYKIYIFMTIVMVVLLLLGK
                     LPLFDSLLLAFGTAGTGGFSILNSGCASYSPYIQYLIAIFMILFGVNFNVYYFILIKKF
                     KDAIHYEELKYYLLFIGASVAMITYNIHSLFPTIEQAFRHALFQVGTVITTTGYASTDF
                     NKWPEFSKFILVMLMFSGACAGSTGGGMKVSRLVIMLKTVKKELLSYLHPRTVRKVKFN
                     GRIVEHEVIRGINVYMIAYAFVLMFSVLIISIDNFDFTSNFTAVVATLNNIGPGLNIVG
                     PTGNFSMYSNLSKIVMIFDMLAGRLELFPMLLL"
     CDS             9867..10136
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1628"
                     /sec_met_domain="PF05402 (E-value: 1.3e-20, bitscore: 70.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.5e-14,
                     bitscore: 50.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNTDFMLRDIAGEVILVPTGAATQQFNGMITLNEVAAFIWKNL
                     DESKSKEELVDKIMDEFEVDEETARTDVEGFVGALYEHGLVLDE"
     PFAM_domain     9909..10124
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1628_0017"
                     /evalue="4.10E-19"
                     /label="ctg1_1628"
                     /locus_tag="ctg1_1628"
                     /protein_end="86"
                     /protein_start="14"
                     /score="68.7"
                     /tool="antismash"
                     /translation="EVILVPTGAATQQFNGMITLNEVAAFIWKNLDESKSKEELVDKIM
                     DEFEVDEETARTDVEGFVGALYEHGLV"
     CDS             10133..10573
                     /locus_tag="ctg1_1629"
                     /transl_table=11
                     /translation="MRQIANNVYIPVLKDLVEEGKEVSMMISGSSMNPFLIHQRDYILM
                     KKPEEELKAGDMVFFQRRDEAYVMHRIHHINKEGKLFIIGDAQVDMEGPIDKEQVFAII
                     TKVKRKGKWIAPGDFWWEFFEHIWLHLIPFRRFLMKLYGIRR"
     PFAM_domain     10154..10450
                     /aSDomain="Peptidase_S24"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00717.25"
                     /description="Peptidase S24-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1629_0018"
                     /evalue="2.40E-07"
                     /label="ctg1_1629"
                     /locus_tag="ctg1_1629"
                     /protein_end="106"
                     /protein_start="7"
                     /score="30.6"
                     /tool="antismash"
                     /translation="VYIPVLKDLVEEGKEVSMMISGSSMNPFLIHQRDYILMKKPEEEL
                     KAGDMVFFQRRDEAYVMHRIHHINKEGKLFIIGDAQVDMEGPIDKEQVFAIITK"
     CDS             10884..11360
                     /locus_tag="ctg1_1630"
                     /transl_table=11
                     /translation="MGRVFKFHNDVDTDQIIASQYLLLPNIEEMKVYTFESIDKDFAKK
                     VKEGDIVVAGENFGCGSSREQAPSVLKALGVKAVVAKSFARIFYRNSINIGLPVIISKD
                     LYDKVEDGADIDINLSEGWIKTEDETLPCTKLPPYMQNILDHGGLINFLNEGEE"
     aSDomain        10887..11345
                     /aSDomain="TIGR02087"
                     /aSTool="tigrfam"
                     /description="LEUD_arch: 3-isopropylmalate dehydratase,
                     small subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1630_0003"
                     /evalue="1.20E-57"
                     /identifier="TIGR02087"
                     /label="ctg1_1630"
                     /locus_tag="ctg1_1630"
                     /protein_end="154"
                     /protein_start="1"
                     /score="192.1"
                     /tool="antismash"
                     /translation="GRVFKFHNDVDTDQIIASQYLLLPNIEEMKVYTFESIDKDFAKKV
                     KEGDIVVAGENFGCGSSREQAPSVLKALGVKAVVAKSFARIFYRNSINIGLPVIISKDL
                     YDKVEDGADIDINLSEGWIKTEDETLPCTKLPPYMQNILDHGGLINFLN"
     PFAM_domain     10989..11174
                     /aSDomain="Aconitase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00694.21"
                     /description="Aconitase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1630_0019"
                     /evalue="3.10E-22"
                     /label="ctg1_1630"
                     /locus_tag="ctg1_1630"
                     /protein_end="97"
                     /protein_start="35"
                     /score="79.4"
                     /tool="antismash"
                     /translation="ESIDKDFAKKVKEGDIVVAGENFGCGSSREQAPSVLKALGVKAVV
                     AKSFARIFYRNSINIGL"
     CDS             11365..12615
                     /locus_tag="ctg1_1631"
                     /transl_table=11
                     /translation="MGMTIGEKIIARAAKVDQVKAGEIHTIEVDRLMSNDGTTHLTIDM
                     YHNQLKHPKIADKDKLVFIMDHNVPAENPKTAAAHRKMRNFAKEHEIKLYEGKGVCHQI
                     MVENHVCPGEFIMGADSHTCTYGALGAFGTGIGCTDFLYAMVTGQSWVLVPDTIRFNLH
                     GKLREGVYARDLMLSIIGMVGANGCNYKIMEFAGEGAHNLDIDERLVLCNLAVEAGAKT
                     GIVEPDEKVVEYVESRGRKAENLFKSDDDAVFEKVYDINLDEIKPVVARPHQIDDVVDA
                     KEVKDVKIDEAFLGSCNNGRIEELRVAAEILKGKKVSDSVRFLIAPASNEVYMQALDEG
                     LIDIFMESGAMVMNCNCSVCWGSCQGVIGKDEVLISTGTRNFKGRAGHPDSYVYLGSAA
                     TVTASAIAGKITTADQI"
     aSDomain        11371..12603
                     /aSDomain="TIGR02086"
                     /aSTool="tigrfam"
                     /description="IPMI_arch: 3-isopropylmalate dehydratase,
                     large subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1631_0005"
                     /evalue="5.30E-144"
                     /identifier="TIGR02086"
                     /label="ctg1_1631"
                     /locus_tag="ctg1_1631"
                     /protein_end="413"
                     /protein_start="2"
                     /score="477.9"
                     /tool="antismash"
                     /translation="MTIGEKIIARAAKVDQVKAGEIHTIEVDRLMSNDGTTHLTIDMYH
                     NQLKHPKIADKDKLVFIMDHNVPAENPKTAAAHRKMRNFAKEHEIKLYEGKGVCHQIMV
                     ENHVCPGEFIMGADSHTCTYGALGAFGTGIGCTDFLYAMVTGQSWVLVPDTIRFNLHGK
                     LREGVYARDLMLSIIGMVGANGCNYKIMEFAGEGAHNLDIDERLVLCNLAVEAGAKTGI
                     VEPDEKVVEYVESRGRKAENLFKSDDDAVFEKVYDINLDEIKPVVARPHQIDDVVDAKE
                     VKDVKIDEAFLGSCNNGRIEELRVAAEILKGKKVSDSVRFLIAPASNEVYMQALDEGLI
                     DIFMESGAMVMNCNCSVCWGSCQGVIGKDEVLISTGTRNFKGRAGHPDSYVYLGSAATV
                     TASAIAGKITTA"
     aSDomain        11374..12600
                     /aSDomain="TIGR01343"
                     /aSTool="tigrfam"
                     /description="hacA_fam: homoaconitate hydratase family
                     protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1631_0004"
                     /evalue="2.20E-152"
                     /identifier="TIGR01343"
                     /label="ctg1_1631"
                     /locus_tag="ctg1_1631"
                     /protein_end="412"
                     /protein_start="3"
                     /score="505.4"
                     /tool="antismash"
                     /translation="TIGEKIIARAAKVDQVKAGEIHTIEVDRLMSNDGTTHLTIDMYHN
                     QLKHPKIADKDKLVFIMDHNVPAENPKTAAAHRKMRNFAKEHEIKLYEGKGVCHQIMVE
                     NHVCPGEFIMGADSHTCTYGALGAFGTGIGCTDFLYAMVTGQSWVLVPDTIRFNLHGKL
                     REGVYARDLMLSIIGMVGANGCNYKIMEFAGEGAHNLDIDERLVLCNLAVEAGAKTGIV
                     EPDEKVVEYVESRGRKAENLFKSDDDAVFEKVYDINLDEIKPVVARPHQIDDVVDAKEV
                     KDVKIDEAFLGSCNNGRIEELRVAAEILKGKKVSDSVRFLIAPASNEVYMQALDEGLID
                     IFMESGAMVMNCNCSVCWGSCQGVIGKDEVLISTGTRNFKGRAGHPDSYVYLGSAATVT
                     ASAIAGKITT"
     PFAM_domain     11386..12588
                     /aSDomain="Aconitase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00330.22"
                     /description="Aconitase family (aconitate hydratase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1631_0020"
                     /evalue="2.70E-90"
                     /label="ctg1_1631"
                     /locus_tag="ctg1_1631"
                     /protein_end="408"
                     /protein_start="7"
                     /score="303.7"
                     /tool="antismash"
                     /translation="KIIARAAKVDQVKAGEIHTIEVDRLMSNDGTTHLTIDMYHNQLKH
                     PKIADKDKLVFIMDHNVPAENPKTAAAHRKMRNFAKEHEIKLYEGKGVCHQIMVENHVC
                     PGEFIMGADSHTCTYGALGAFGTGIGCTDFLYAMVTGQSWVLVPDTIRFNLHGKLREGV
                     YARDLMLSIIGMVGANGCNYKIMEFAGEGAHNLDIDERLVLCNLAVEAGAKTGIVEPDE
                     KVVEYVESRGRKAENLFKSDDDAVFEKVYDINLDEIKPVVARPHQIDDVVDAKEVKDVK
                     IDEAFLGSCNNGRIEELRVAAEILKGKKVSDSVRFLIAPASNEVYMQALDEGLIDIFME
                     SGAMVMNCNCSVCWGSCQGVIGKDEVLISTGTRNFKGRAGHPDSYVYLGSAATVTASAI
                     AG"
     CDS             12636..13127
                     /locus_tag="ctg1_1632"
                     /transl_table=11
                     /translation="MEQFKGKVWVLGDDIDTDIIIPTEYLALPTVEDMKQYGFSPLRPE
                     LAGQIGEGDIIVAGSNFGCGSSREQAPEIIKALKVKCVIAKSFARIFFRNSINNGLLLI
                     ENDKIQDAVKEGDEIEVTLGEKITYNGTDYEIHSLPDNLMEIINAGGLVEAMKKRNGVK
                     "
     aSDomain        12651..13112
                     /aSDomain="TIGR02087"
                     /aSTool="tigrfam"
                     /description="LEUD_arch: 3-isopropylmalate dehydratase,
                     small subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1632_0006"
                     /evalue="1.00E-52"
                     /identifier="TIGR02087"
                     /label="ctg1_1632"
                     /locus_tag="ctg1_1632"
                     /protein_end="159"
                     /protein_start="5"
                     /score="176.0"
                     /tool="antismash"
                     /translation="GKVWVLGDDIDTDIIIPTEYLALPTVEDMKQYGFSPLRPELAGQI
                     GEGDIIVAGSNFGCGSSREQAPEIIKALKVKCVIAKSFARIFFRNSINNGLLLIENDKI
                     QDAVKEGDEIEVTLGEKITYNGTDYEIHSLPDNLMEIINAGGLVEAMKKR"
     PFAM_domain     12795..12950
                     /aSDomain="Aconitase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00694.21"
                     /description="Aconitase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1632_0021"
                     /evalue="4.80E-18"
                     /label="ctg1_1632"
                     /locus_tag="ctg1_1632"
                     /protein_end="105"
                     /protein_start="53"
                     /score="65.8"
                     /tool="antismash"
                     /translation="DIIVAGSNFGCGSSREQAPEIIKALKVKCVIAKSFARIFFRNSIN
                     NGLLLIE"
     aSDomain        13144..14367
                     /aSDomain="TIGR02086"
                     /aSTool="tigrfam"
                     /description="IPMI_arch: 3-isopropylmalate dehydratase,
                     large subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1633_0007"
                     /evalue="3.70E-154"
                     /identifier="TIGR02086"
                     /label="ctg1_1633"
                     /locus_tag="ctg1_1633"
                     /protein_end="408"
                     /protein_start="0"
                     /score="511.3"
                     /tool="antismash"
                     /translation="MIEKIISRNVGVDSVKPGQIQTVNVDRVMIHDIFIPFVAEKFEEM
                     GFTKLWDPDKVVLIYDHMVPASTTDDIRHFKIGDAFAKKYGMKNVHRSDGICHQLMTEC
                     GYAKPGNIVFGTDSHTTTYGCVGCFSSGIGYTEMAAILGTGEMWVRVPETIKVVIDGKL
                     PENVSSKDIILRLIGDLTAAGATYKALEFSGSTVDEMSVAARMTMSNMAIEAGAKAALF
                     APDEKTAEYSKVDLADVDWLYGDEDAEYCQTITYKAEDLVPVVACPSQVDKIRAVKEVE
                     GTELDQVFIGSCTNGRLEDLKAAAEILKGKKVADYVKLIVTPASRKIYKQAVDAGYMKI
                     LAEAGAIITHPGCGLCCGRAGGIMTDGERVLATNNRNFLGRMGTSKVEIYLGSPKTAAA
                     SAIAGKIVE"
     CDS             13144..14373
                     /locus_tag="ctg1_1633"
                     /transl_table=11
                     /translation="MIEKIISRNVGVDSVKPGQIQTVNVDRVMIHDIFIPFVAEKFEEM
                     GFTKLWDPDKVVLIYDHMVPASTTDDIRHFKIGDAFAKKYGMKNVHRSDGICHQLMTEC
                     GYAKPGNIVFGTDSHTTTYGCVGCFSSGIGYTEMAAILGTGEMWVRVPETIKVVIDGKL
                     PENVSSKDIILRLIGDLTAAGATYKALEFSGSTVDEMSVAARMTMSNMAIEAGAKAALF
                     APDEKTAEYSKVDLADVDWLYGDEDAEYCQTITYKAEDLVPVVACPSQVDKIRAVKEVE
                     GTELDQVFIGSCTNGRLEDLKAAAEILKGKKVADYVKLIVTPASRKIYKQAVDAGYMKI
                     LAEAGAIITHPGCGLCCGRAGGIMTDGERVLATNNRNFLGRMGTSKVEIYLGSPKTAAA
                     SAIAGKIVEA"
     aSDomain        13147..14367
                     /aSDomain="TIGR01343"
                     /aSTool="tigrfam"
                     /description="hacA_fam: homoaconitate hydratase family
                     protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1633_0008"
                     /evalue="1.20E-152"
                     /identifier="TIGR01343"
                     /label="ctg1_1633"
                     /locus_tag="ctg1_1633"
                     /protein_end="408"
                     /protein_start="1"
                     /score="506.3"
                     /tool="antismash"
                     /translation="IEKIISRNVGVDSVKPGQIQTVNVDRVMIHDIFIPFVAEKFEEMG
                     FTKLWDPDKVVLIYDHMVPASTTDDIRHFKIGDAFAKKYGMKNVHRSDGICHQLMTECG
                     YAKPGNIVFGTDSHTTTYGCVGCFSSGIGYTEMAAILGTGEMWVRVPETIKVVIDGKLP
                     ENVSSKDIILRLIGDLTAAGATYKALEFSGSTVDEMSVAARMTMSNMAIEAGAKAALFA
                     PDEKTAEYSKVDLADVDWLYGDEDAEYCQTITYKAEDLVPVVACPSQVDKIRAVKEVEG
                     TELDQVFIGSCTNGRLEDLKAAAEILKGKKVADYVKLIVTPASRKIYKQAVDAGYMKIL
                     AEAGAIITHPGCGLCCGRAGGIMTDGERVLATNNRNFLGRMGTSKVEIYLGSPKTAAAS
                     AIAGKIVE"
     PFAM_domain     13153..14355
                     /aSDomain="Aconitase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00330.22"
                     /description="Aconitase family (aconitate hydratase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1633_0022"
                     /evalue="1.20E-94"
                     /label="ctg1_1633"
                     /locus_tag="ctg1_1633"
                     /protein_end="404"
                     /protein_start="3"
                     /score="318.1"
                     /tool="antismash"
                     /translation="KIISRNVGVDSVKPGQIQTVNVDRVMIHDIFIPFVAEKFEEMGFT
                     KLWDPDKVVLIYDHMVPASTTDDIRHFKIGDAFAKKYGMKNVHRSDGICHQLMTECGYA
                     KPGNIVFGTDSHTTTYGCVGCFSSGIGYTEMAAILGTGEMWVRVPETIKVVIDGKLPEN
                     VSSKDIILRLIGDLTAAGATYKALEFSGSTVDEMSVAARMTMSNMAIEAGAKAALFAPD
                     EKTAEYSKVDLADVDWLYGDEDAEYCQTITYKAEDLVPVVACPSQVDKIRAVKEVEGTE
                     LDQVFIGSCTNGRLEDLKAAAEILKGKKVADYVKLIVTPASRKIYKQAVDAGYMKILAE
                     AGAIITHPGCGLCCGRAGGIMTDGERVLATNNRNFLGRMGTSKVEIYLGSPKTAAASAI
                     AG"
     CDS             14468..15631
                     /locus_tag="ctg1_1634"
                     /transl_table=11
                     /translation="MTNLLISLFIKDKENVKDAKVRNAYGKMAGIVGICCNIFLFATKF
                     FAGIITGAISITADAFNNLSDAASSIITLVGFGMAGKPADEDHPFGHGRMEYVSGLVVS
                     ILILMMGVELFKTSVEKVIHPEVITEQWISYVILVISIALKFWMYMFNKGIGWRIHSET
                     MKATAADSLNDCISTAAVVGGMLVFHYFHLNVDGIVGIFVACFVLWGGYESIKDTMNPL
                     LGESPDPELIAKITETVLNHKMVIGVHDIVVHDYGPGRRIVSLHAEVPYNKDMMEVHDL
                     MDHIEMRLMEEYHCEATIHMDPVVTDDEEVNETRKEVFNIVKKYDKTLSVHDFRMVKGP
                     THTNVIFDLVIPYGKDYEPEKIVKDLKQKIKDEMQGKHYAVIRVDRF"
     aSDomain        14555..15379
                     /aSDomain="TIGR01297"
                     /aSTool="tigrfam"
                     /description="CDF: cation diffusion facilitator family
                     transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1634_0009"
                     /evalue="5.30E-62"
                     /identifier="TIGR01297"
                     /label="ctg1_1634"
                     /locus_tag="ctg1_1634"
                     /protein_end="304"
                     /protein_start="29"
                     /score="207.6"
                     /tool="antismash"
                     /translation="GIVGICCNIFLFATKFFAGIITGAISITADAFNNLSDAASSIITL
                     VGFGMAGKPADEDHPFGHGRMEYVSGLVVSILILMMGVELFKTSVEKVIHPEVITEQWI
                     SYVILVISIALKFWMYMFNKGIGWRIHSETMKATAADSLNDCISTAAVVGGMLVFHYFH
                     LNVDGIVGIFVACFVLWGGYESIKDTMNPLLGESPDPELIAKITETVLNHKMVIGVHDI
                     VVHDYGPGRRIVSLHAEVPYNKDMMEVHDLMDHIEMRLMEEYHCEATIHMDPV"
     PFAM_domain     14558..15133
                     /aSDomain="Cation_efflux"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01545.23"
                     /description="Cation efflux family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1634_0023"
                     /evalue="1.10E-44"
                     /label="ctg1_1634"
                     /locus_tag="ctg1_1634"
                     /protein_end="222"
                     /protein_start="30"
                     /score="152.7"
                     /tool="antismash"
                     /translation="IVGICCNIFLFATKFFAGIITGAISITADAFNNLSDAASSIITLV
                     GFGMAGKPADEDHPFGHGRMEYVSGLVVSILILMMGVELFKTSVEKVIHPEVITEQWIS
                     YVILVISIALKFWMYMFNKGIGWRIHSETMKATAADSLNDCISTAAVVGGMLVFHYFHL
                     NVDGIVGIFVACFVLWGGYESIKDTMNPL"
     PFAM_domain     15149..15376
                     /aSDomain="ZT_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16916.7"
                     /description="Dimerisation domain of Zinc Transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1634_0024"
                     /evalue="2.60E-14"
                     /label="ctg1_1634"
                     /locus_tag="ctg1_1634"
                     /protein_end="303"
                     /protein_start="227"
                     /score="53.2"
                     /tool="antismash"
                     /translation="DPELIAKITETVLNHKMVIGVHDIVVHDYGPGRRIVSLHAEVPYN
                     KDMMEVHDLMDHIEMRLMEEYHCEATIHMDP"
     CDS             15628..16161
                     /locus_tag="ctg1_1635"
                     /transl_table=11
                     /translation="LICSLKTKIIGEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXT"
     CDS             16471..16572
                     /locus_tag="ctg1_1636"
                     /transl_table=11
                     /translation="MLTITELIAVISLCVAFYSLGYVCGKHDAKIEK"
     CDS             complement(16753..17358)
                     /locus_tag="ctg1_1637"
                     /transl_table=11
                     /translation="MLDKSLIYKDIVMCLPFEDLEDLKVPVLPDGYSYKMFESGDEIAW
                     AKLEVLVGEFDCFEDASAYFAKTFLTHEELLADRVCFIVNPEGEIVATTSAWFKTNGDI
                     RFPLIHWVSTSPKEQGKGLGKAIVLFALSRFLVVEPDADFIFLHTHTWAYKAVGMYQKM
                     GFRITKKALPTSRTDFSCMDVLKDVLPNSIIAQLLEKD"
     PFAM_domain     complement(16864..17166)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1637_0025"
                     /evalue="2.10E-08"
                     /label="ctg1_1637"
                     /locus_tag="ctg1_1637"
                     /protein_end="165"
                     /protein_start="64"
                     /score="34.5"
                     /tool="antismash"
                     /translation="FAKTFLTHEELLADRVCFIVNPEGEIVATTSAWFKTNGDIRFPLI
                     HWVSTSPKEQGKGLGKAIVLFALSRFLVVEPDADFIFLHTHTWAYKAVGMYQKMGF"
     CDS             complement(17433..18068)
                     /locus_tag="ctg1_1638"
                     /transl_table=11
                     /translation="LLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCIKSNKSKFTVCMFYYIALHFQDN
                     RKLKFSHFNLVRIKIKDFPNISLNRCLIIFLAIKIRFVESTFCLIYTP"
     CDS             18146..19327
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 81.4; E-value:
                     1.2e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1639"
                     /transl_table=11
                     /translation="MTKDGYYTSGEFAKKANVTLRTIRYYDRQGILKPSKVADNGYRLY
                     TDADFAKLQKILSLKYLGFSLEEIMTMTINDEDQDFIKESIGLQLYLVQKKMEHLKLVE
                     QSLEEMEQKMDNEEEIDWTQMMNLLHVTNLEKGLVEQYKNASNLDIRIGLHQKYSQNPQ
                     PWFEWIYEQLNLKEKDEVLELGCGTGELWKNKNLPKNVHVTLSDQSQGMVKDARNYVGE
                     GKGQISYQMIDCRQIPKEDHSFDKVIANHVLFYLDDRQQVFNEIKRVLKQNGTFICSTY
                     GSSHMQEITQLIKDFDERITLSDHKLYNVFGLENGEEQLKKVFSQVKEIDYEDELLVDQ
                     PEPLISYILSCHGNQHEYLNHRYLEFKDFVRKKMAAKGVIKITKSAGIFICKP"
     PFAM_domain     18164..18358
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1639_0026"
                     /evalue="8.20E-18"
                     /label="ctg1_1639"
                     /locus_tag="ctg1_1639"
                     /protein_end="71"
                     /protein_start="6"
                     /score="64.3"
                     /tool="antismash"
                     /translation="YTSGEFAKKANVTLRTIRYYDRQGILKPSKVADNGYRLYTDADFA
                     KLQKILSLKYLGFSLEEIMT"
     PFAM_domain     18689..18979
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1639_0027"
                     /evalue="1.40E-18"
                     /label="ctg1_1639"
                     /locus_tag="ctg1_1639"
                     /protein_end="278"
                     /protein_start="181"
                     /score="67.4"
                     /tool="antismash"
                     /translation="LELGCGTGELWKNKNLPKNVHVTLSDQSQGMVKDARNYVGEGKGQ
                     ISYQMIDCRQIPKEDHSFDKVIANHVLFYLDDRQQVFNEIKRVLKQNGTFIC"
ORIGIN
        1 atgaagaaaa atctggttgt gatcgaggaa ttaaaaaaac agggaaaagc attattagat
       61 gcgagaagag ataactttgt cagacaaagt cttttgtcag atgaattttt gaattttatg
      121 caacaaaata agaagccgtt tgatctttta atgtcatatt atgaatgcgc gatcatggaa
      181 gtggaaacaa aattcagagt attaaatcat gaattatctt tggaatatga taataatccg
      241 attgagagta ttaagacaag agtcaaatca tacgatagca ttttgaagaa gatccgaaga
      301 aaaaatattc cattaaatct aagggcgatt gaagataatt taaaagatat tgccggggtc
      361 agagttatct gttcatttcc agatgacatt tataaattag cagaaagttt cttaaagcaa
      421 gatgatatca cactgatcga gcgaaaagat tatattaaga atccaaagcc aagtggatat
      481 cgaagtcttc atctgatcgt acaagtaccg atctttttac aaaatgaaaa gaagatggtg
      541 aatgttgaag tgcaatttcg aacgatcgct atggatttct gggcaagtct tgaccataag
      601 atgcgttata agaaagagtt gtctgatgaa gaagtggaaa tccttcagga agaactttat
      661 gattgtgcaa gacaaagtgc agtacttgat gagagaatgc agggaatcag ggatcgtatt
      721 acaaagaaac aagaacagga aacgatattg ttagaagata agaacagcaa agactggtta
      781 taaaacataa gtgtgacaaa cgtacatata ggagatatca tatatcagga aatgatcata
      841 gatatctcct ttttttattc gtttccacat taatatggaa gctaatgtaa ttgcaagaaa
      901 taagatatca atggtattct agttacagaa agaaaaacgt taattaacag attaggggtg
      961 attgatttga ttcgtcgaca aatcgaatta ttaaaacttt tgtcaaaaca aagggaatat
     1021 aaacccgcat ctttctttag taaatcatta gatgtttcga caaaaacgat ttacacagat
     1081 attacttatc ttcaaagtga agttgaaaag tataaagttg atctggtcag agctccaaga
     1141 ataggaattc gtctggaagg tgaaaaggaa aacattcagc atatgttaag agaccttcaa
     1201 aaggataatc tgtctgaaga tgaaaaatat acaccggagt atcgcagatt gtggatttta
     1261 aagaaggtat tgatcgattg tgaaataatc acattggaat cagtatcaaa ggaattttta
     1321 gtaagtaaaa catcactgta tcaggacatt gcagtgatca ataaatcaat cgaaagtcag
     1381 tcagatgtaa aactggaagt tggagaatgt ggaatctgta ttttaggaga agaaagcgag
     1441 atacaaaatg cagtgaacaa ttatttgtta tcagaatcaa aggaagaaat gttttctgat
     1501 tttacgcaca aacttggaaa cttttttgaa cttgatgtga taaaagcagt ttcagatctt
     1561 attttaaatg attttgaaga actgaccgaa gtgctttcag aatattatct gaaatcttta
     1621 ttggtaacat tgatcatgca aagttcaaga ttgctcaaaa agaaacatat gaatgaggaa
     1681 acagaaattt cttacaacaa tatccggcat atggagacat acatcgtggc aaatagtatt
     1741 gcggaacagc tgaaatacca gcttcatatt acatacagta ataatgatat ggaatattta
     1801 tgcagacagt tatatgccca cagagtgaca catcatgtaa aacatatgcg gacagactat
     1861 gaagaaacgg taagagatgt catcaagaga atgagtgaga ttcaaaagct tgatctgaca
     1921 agggacaaga aattatatga gtcattgtta tatcatctgc caccgatgat cttaagattg
     1981 caaaataata ttcagatcgt aaatccgatg cttgataata tcaaacagga gtatccggaa
     2041 ctttttacaa cgatgtggta tgcacttaca caaatagaat taaggtatca ggtaacatta
     2101 acagaagatg aagtttcact aatcttatta cattttcaag tggcattaga ccaatttgaa
     2161 caagttggaa atattgttgt tgtatgtacc tatggagtta gttcttctca gctcatttta
     2221 agcagggtaa aacaaatact tccggcaaaa gataatatta cggtgacaaa cacaaagaaa
     2281 ttaaaagaga tcgatcttag taaagtagat ctgatcatat catctgttga tattgaggat
     2341 ccagagattt cttatgtgaa ggtaaatccg ctgcttacaa aagatgatta tgccaatatc
     2401 ctagatgcat atacaaaaca ggtattactg atcaaaaata atgtgtgtga taaccagaaa
     2461 aatggaatta aagcaccgac attgaaaaaa tatttggaag ggaaatttat tttccttaaa
     2521 caagatcttg atagtaaaga aaagtgtcta gattttatta ttgatgtatt agaaaaagat
     2581 aatgcagtgt atgatgaatt tagggaagct atttacaaaa gagaaaaact tggtgtgaca
     2641 tgtttggata caggtgtggc actgccacat gcagatccgc agacgattaa aaaatccaga
     2701 ataatcctat taactttaaa acatcccgtt gactggggtg gaactttagt atcactgatc
     2761 gttgtaactg catttccaga agaagaaatg aaccagattc gggatgtgat caatgaactc
     2821 tatcagctta ttggagaaaa agaagatgta aatacgttta taagattcga aacaatacaa
     2881 gaagttttaa aagtatttca tgaatcatga tatgaaagga gaacttgaat gtattttgac
     2941 cagagattgt gtttctttca tcaaaaagtg gaaagtcagg atcagttgtt tcagatgatg
     3001 acagataaaa tgttagaagc aggatgtgta aaagaaaatt actatgaagg aatcagtaac
     3061 agagaaaaag aatatcctac aggattatta gtaaatcaga caggctttgc gattccgcat
     3121 acagactctg agcgagtgaa taaatcacag atttgctttt tatcattaga tgagccaatt
     3181 gaatttgaag atatggtgga taaaagtcat aagatttcag tggaattggt atttatgtta
     3241 gcaatggcac agccacatga gcaggtaaat acattacaga atttgatcgc actgtttcag
     3301 gatgatgaaa aagtagcaaa gttgaaagaa tgtaacacag agaaagaact tatgcagatt
     3361 ttaaatgcat caggaattga ataagcgata gagaaagaga gaagaagaaa tgttaagtgt
     3421 attacaatgg tttatcggat tagggtcaac ggtattttta ccgatcatta ttttcatatt
     3481 aggtattatt tttggagtaa aaccagcaaa agcagcgatt tcaggtttta cagttggaat
     3541 tggtagtatt ggtctgaatc tggtcattgg attattatca gataaccttg gaacggcaat
     3601 acaggtaatg ggagaacatt acggattttc actaaatatt atggatattg gttgtggtgt
     3661 cggtggaccg ctggcattct caacaacatt tggaattata ttgatcccaa tgtcattgat
     3721 cgttaattta ttatttgtca tgcttgggtg gacaaaaact ttaaatgtag atatctggaa
     3781 cttctggttt ccatgtttcc ttggattagt tgcacaggca gttacaggaa attttgttac
     3841 aggaatttta ggagcactag ttgcagttat gcttcagtgg ttattagcag acattttcca
     3901 gaagaaagtt agtgaatttt ttggatatcc aggaattgca atttctcata tgatggcgtt
     3961 atcaggagca ttgatcgcag taccattaaa ctggattttt gatagaattc cgggatttaa
     4021 taaaattgaa gccgactcag aaacgatcgc aaaacgtttt ggattttttg gagatacagt
     4081 tgttatcgga atcatcattg gaatgatcgt aggattcttg gcaaaatatg atttcgcaaa
     4141 agctgcacag ttaggaatgg caacaggtgc ggttatgaaa atcatgccaa agatggtagc
     4201 aatgtttatg gaagggttaa tgccaattgc agaagctgcc aaagaattcg ccaataagag
     4261 attaggtgga agaagtgtaa atattggtat ggatgctgct ctaactgttg gacattctac
     4321 agttatgagt acaaacttat taatggtacc aatttcttta gcattagcga tcatcttacc
     4381 aggaaaccag accttaccat tcggagatct tgcattctat gcatttggaa tctgtctaat
     4441 gatcccaatc tttagaggaa atgttgtgag atctattgta ggatgtagta tttatatggt
     4501 atctatgctg tatctttcta catggcttgc accaatcatt acaaatgtat ttaagatcgc
     4561 acattataat gttggaacaa gtggacaggt aacatccgta ctttgcggta tctggccagc
     4621 gggattattc gcagttgcaa caaaatcatt aggaaatatt ggattagcag tgattggagt
     4681 tgtcgtgatc gcattactag tatatgtaaa taaaatcaga gcacagaaag aaaattagaa
     4741 tctttataaa ataagatatt tcataggagg tagtatcatg aaaaaattat taattgtatg
     4801 tggagcagga catgcaacat ccacaattgc ggtagcaaaa gtcagcgcat ggttagaaaa
     4861 agaaggatac agcgataaag taaagattta tcagtctaag attgccgacg aattaaataa
     4921 aattgatgat tatgatgcgg tgatatcaac aacgatcgtg ccagattcta tcaaagataa
     4981 agtcattcag ggattaccat tattaaacgg aatgggagta gatcaggtat acgatcagtt
     5041 aaaaacaaga cttggattat aggagcagat catgggagtt ttttttggag aagtgacatt
     5101 agaaacagtt aaaggaagag catcttatca tgacatttct gatgaaatca gagaaaatat
     5161 caaaaaatct gagttaaaaa atggatgtgt tgtcatatca agtgcgcata ccacatgttc
     5221 tctgtatttt gacgaatgta tgcatgacac aaattactgg ggagatgaat atctgcaggc
     5281 agatattaat gatgtgatgg aaaaaattgc gccatccatg aaaatggaaa atcagtatca
     5341 tagtccagga ccaaaacata ttgaatttgg attaagtctt ggatctaagg attatccagc
     5401 agaaaaatgg acaatgctta atacagatgc acatctgaaa tcttccattt ttggcagccc
     5461 gtcattaaca tttatcgtaa aagacggaga aatccaactt ggagctttgg gaaaagtcta
     5521 ttttgtagac tgggatcagt taagagaacg aacaagaaaa gtacagatta tggtgatggg
     5581 agaataaaaa tgaaaattat cagtccttca ttattaaatt cagatacata tcagattaag
     5641 gagcagtttg aagcattaga aaaatgtgga ataaactaca ttcatattga tattacagat
     5701 ggacattttg taccaatgat ctcgtttggc gcaaatacag taaaagatct gagaaaacat
     5761 actgattttg tactggattg tcatctgatg gttgaaaatc cagaaaatct gataccagtg
     5821 attgcggatg cgggggcaga tatcatcacc gtgcatacag aggcaacgaa gcatatctac
     5881 cgatctattc agacaatcaa aaagtgtgga aaaaaagccg gaattgcgat caatcccgga
     5941 actccggtat ctatgatcaa ggagattttg ccaatggctg atcttgtcct ttgcatgacc
     6001 actaatcccg gtgtgtttgg agaaagtttt attccatcag ttgcagacaa agtaaagaat
     6061 ctttgtgaat tgagagaaca aaaaggatat tcttatcaga ttcaggtaga tggaagcatt
     6121 aatgatcaaa cagccattgt gtgtaaaaag gcaggcgcag atatttttgt ttcaggaagc
     6181 tatatatttg gaggaaatat cgaagaacga attcacaaga ttatggatgc aggagaagag
     6241 atgtgaaagt aaaagaaaat ttagaacata ttttaaagga acttcaagac gcaactttta
     6301 aaatagaaga agaacagatt gaaaatgttt taaaactgat agcaccagac aaaaagatat
     6361 ttttaactgg aaaaggaaga tcagggttgg cggcgaaggg ttttgcaaac agattgatgc
     6421 atcttggatt tcaggcgtat gtcattggag aaatttcaac accacatacg aaagctggag
     6481 atctattgat cataacatct gggtcaggag aaacagatgc cttggtcagt attgcaaaaa
     6541 aagccaaaga atctggacta tatcttggac ttgttacaat gaatccgcaa tccacactgg
     6601 ggaaaatggc agatgggatg atcatacttc caggtgactc caaaggaaat aatgaagaga
     6661 aacattcgat acagccaatg ggaagtcagt ttgaacagat gtcattttta atcttcgatg
     6721 caatcgtatt aaaacttatg gaaaactgga atcagacatc ggagcagatg tttatgcggc
     6781 atgcagattt agaataatga tatccatgcg ttgaaagatg atgtgtggga agaaaatatc
     6841 ctgtaagatc agataaatta tgtttggtct tacaggatat ttttagatgt cataattaaa
     6901 aggatatttc ttaaattgta atttctgaca gactgtgata gaataggaca agtattaaaa
     6961 aaagtataaa aatttgttaa gaaagtgtta atgaattgag ggtaaaaaat gaatattatc
     7021 attgttgggt gtggtagaat cggttctacg cttgttgagg aattaagtgg cgagaaccat
     7081 gacatttcca ttattgatga gaaagcacat gttgtacaga aacttgctga aacacatgat
     7141 gtattaggtg tgatcgggaa tggagcaagt tatagtattc tgtcagacgc aggagttgag
     7201 acagcagata tcattattgc agttacgaac tctgacgaat tgaatctttt gtgttgtctg
     7261 atcgcgaaga aggcaggaag atgtgagacg gttgccagag tgagaaatcc tgtttattat
     7321 gatgagatca gtttcataaa ggaagagatg ggaatttctg ttgtgctgaa tccagaatta
     7381 agtgcggcat atgagattgc aagattacta agattccctt ctgcaatgga agtgaataag
     7441 ttttctaaag gcaggatcga gatgttaaaa taccgtatcc cacataattc taaattagat
     7501 ggaatgacat tgatcgatgt cagtaatcag ttaaattgtg agatattgat ctctgcggta
     7561 gagcgtaaga aagaattgat cattccaaat ggttcttttc agttaagaga gaaagatata
     7621 atttcatttg ttggaaggcc aaactgtgca atggaatttt tcaggaagat tggggaaaga
     7681 aagaatcagg ttcatgaagc aatgatcata ggtggaagta agattggatt ttatttatca
     7741 aaattacttg tttctagtgg aattggtgta aaactgatcg ataaagacag agatcaatgt
     7801 gagagattaa atgagagtat tccagatgcg atgatcatcc atggaaatgg aaatgaccat
     7861 gatatgctgt tagaagaagg tctgacggat gtagatgcat ttattgccct tacgaatcac
     7921 gatgaggaga atatgtttct gtctctgtat gcacagagcc agagtgatgc aaaattggtc
     7981 acaaaggtac agaaattgaa ttacgatgcc atgatcgaac gattagatct tggaagtatg
     8041 atctatccgg aatatctgac agcacaatat attattcagt atgtaagagc aagacaaaat
     8101 tccatcggaa gtaatattga gaatctctac aaattaatgg atggaagagc ggaagcactg
     8161 gaatttcata ttcagaaagg ttctccagtc attggaagac caattaaaga tctgtcattg
     8221 attgataatc tgctgatctg cagcatttat cgtaaaggaa aaccaatgat tccaaatggt
     8281 caagatcata tggaagaaga tgatctggtg gtagttgtca caactaaaaa aggattacac
     8341 gatgtcaaag acatcttaaa gagaggataa tgggggcagg gtataatgaa tttttcaatg
     8401 attcgatacg taataggttt ggtaatgctc tttgagagtg catttttatc acttccttgt
     8461 ctgatcgcat taatctatca tgagaagaaa ggcttttctt tctggatcat gctatttgta
     8521 tgtctgatca ttggaattct ttttgttatg aagaaaccaa agaagacagt ttattacgca
     8581 aaagaaggtt ttttaacagt tgcgatcagt tggatcgtga tgagtttttt tggagcactg
     8641 ccatttgtga tcaatggaga tattccatca gttgtagatg cgatgtttga aacggtttca
     8701 ggatttacta caacaggatc aagtatctta acggatgtag aagcgttagc aagatgtagt
     8761 ttattctgga ggagttttac tcactgggta ggtggtatgg gtgtattcgt gtttgtatta
     8821 gctgtcatgc cattggttgg tggtcagaat attcatctga tgagagcaga aagtccagga
     8881 ccatctgttg gaaaactggt tcctaagatt cgaaaaacat ctatgatctt atataagatt
     8941 tatattttta tgactattgt gatggtagta ttgttgcttt taggaaagct tccattattt
     9001 gattcgctgt tacttgcatt cggtactgct ggaactggtg gattctcgat attgaattca
     9061 gggtgtgcat cttactcacc atacatacaa tatttgatcg cgatctttat gatcttattt
     9121 ggagtaaatt ttaatgtata ttattttatt ttgatcaaga agttcaaaga tgcgatccat
     9181 tatgaagaat taaaatatta cttattattt attggtgcat ctgtagcaat gatcacatat
     9241 aatatacaca gtttatttcc aacgatcgag caggcattcc gccatgcact ttttcaagta
     9301 ggaacagtga tcacgacaac cggatatgca tcaacagatt ttaataaatg gccggaattt
     9361 tcaaagttta ttctggtaat gctgatgttt tcaggagcat gtgccggaag taccggtggt
     9421 ggtatgaaag tatcaagatt ggtcattatg ttaaagaccg tcaagaaaga gctgctctca
     9481 tacttacatc caagaacggt acgtaaggtc aaattcaacg gaagaattgt agaacatgaa
     9541 gttattcgag ggatcaatgt ttatatgatc gcatatgcat ttgtactgat gttttctgta
     9601 ctgatcattt ctattgataa cttcgatttt acaagcaatt ttacggcagt tgttgcaaca
     9661 ttgaataata ttggtcctgg gcttaatatc gtaggaccaa ctggaaactt ttcaatgtat
     9721 tcgaatcttt ccaagatcgt tatgatcttt gatatgttag cgggaagact ggaattattt
     9781 ccaatgttat tgttgatcaa tccatataca tggaaagaaa taaaaataag aaaaaataaa
     9841 aaaaataaga aagagggcca tagcatatga aacgtaatac agattttatg cttcgtgata
     9901 tcgcaggtga agtaattctt gtaccaacag gggctgcaac tcagcagttt aatggaatga
     9961 tcacattaaa tgaagtggca gcatttattt ggaagaattt agatgaatcg aagtcaaaag
    10021 aagaattggt tgataagatc atggatgaat ttgaagtaga tgaagaaaca gcaaggacag
    10081 atgtagaagg atttgtcgga gcactttatg aacatggact ggtattggat gaatgagaca
    10141 gattgcaaat aacgtttata tcccggtatt gaaagatctg gtagaagagg gaaaagaagt
    10201 cagcatgatg atcagtggga gcagtatgaa tccgtttttg atccatcaaa gagactatat
    10261 tttgatgaag aagccagaag aagaattgaa agctggggat atggtgtttt ttcagagaag
    10321 agatgaggcg tatgtgatgc atcggattca tcacatcaac aaggagggaa aactgtttat
    10381 tatcggagat gcacaggtag atatggaagg accgattgac aaagaacagg tttttgcgat
    10441 cattacaaaa gtaaagcgta aaggaaaatg gatcgcacct ggagattttt ggtgggagtt
    10501 ttttgaacat atctggctgc atttgattcc atttcggaga tttttgatga aattatacgg
    10561 aattcgaaga taaagggtgg taatatttta cgtattacca ttcttttttt gttatcagac
    10621 tatgatgaga gtgtcaaaag taaattttgc cactctctga tgcatccaga ttgttccatt
    10681 gctacgcaat tccgcaatct tcgaacacct cgaactccca taaaatggtg tattcacacc
    10741 attttattcc gttctcgttg ttcggtgtgt caataaatat aaattgctta tttgtgcaag
    10801 cacaaacgca atttatactt ttgacactta catcatttta tagtatcctt aaaaataaaa
    10861 gatacaaaac aggaggaaga tcaatgggac gtgtatttaa attccataac gacgtagata
    10921 cagatcagat catcgcgtca caatatttgt tattgccaaa tattgaagag atgaaagtat
    10981 atacttttga atcaattgat aaagattttg ccaagaaggt aaaagaagga gatattgttg
    11041 tagcaggaga gaactttgga tgtgggtcat ccagagaaca ggcgccaagt gtactgaaag
    11101 cgttaggtgt caaagcagtg gttgctaaat catttgcgag aatcttctat agaaactcta
    11161 tcaatatcgg attaccagtg atcatcagca aagacttata tgacaaagtg gaagacggag
    11221 ctgacattga tatcaacctg tctgaaggat ggatcaaaac agaggatgaa acccttccat
    11281 gtaccaagct gccaccatat atgcagaata tcttagatca tggcggattg atcaatttct
    11341 tgaatgaagg ggaggaatag gaacatggga atgaccatcg gagaaaagat tattgcaaga
    11401 gctgcgaaag tagatcaggt aaaagcagga gagatccata cgattgaagt tgaccgttta
    11461 atgagtaatg atggaacgac acatttaaca attgatatgt atcataacca gttaaaacat
    11521 ccaaagatcg cggacaaaga caaactggta tttatcatgg accacaatgt gcctgcggag
    11581 aatccaaaaa cagcagcagc acatagaaag atgcgtaatt ttgcaaaaga gcatgagatc
    11641 aaattatatg aaggaaaagg tgtctgccat cagattatgg tagagaatca tgtatgtcca
    11701 ggagaattta tcatgggtgc agactcccat acgtgtacat atggagcttt aggagcattt
    11761 ggtacaggaa tcggatgtac tgatttctta tacgctatgg taacaggaca gtcttgggta
    11821 ttagttccag acacgatccg ttttaacctg catggtaaat taagagaagg tgtatacgcc
    11881 agagatttaa tgctttctat catcggaatg gttggagcaa atggatgtaa ctacaagatc
    11941 atggaatttg ctggagaagg tgctcataac cttgatattg atgaacgttt agttctttgc
    12001 aaccttgctg ttgaagcagg agctaagact ggaatcgttg agccagatga gaaagttgta
    12061 gaatacgtag aaagtcgtgg aagaaaagct gagaacttat tcaagagcga tgatgatgcg
    12121 gtatttgaga aagtttatga tatcaactta gacgagatca aaccagttgt tgcaagacct
    12181 catcagatcg atgatgttgt ggatgccaaa gaagtcaagg atgtgaaaat cgatgaagca
    12241 ttcttaggat catgtaacaa tggacgtatc gaagaattaa gagtcgctgc tgaaatctta
    12301 aaaggtaaga aagtaagtga cagcgtaaga tttttgatcg caccagcttc caatgaagtt
    12361 tatatgcagg cattagatga aggtctgatc gatattttca tggaatccgg agcaatggtt
    12421 atgaactgta actgcagcgt ttgctgggga agctgtcagg gtgtcatcgg gaaagatgaa
    12481 gttttgattt ctacaggaac aagaaacttc aaaggacgtg ccggacatcc ggattcttat
    12541 gtatatttag gatcagcagc gacggtcaca gcatcagcga tcgcaggtaa gatcacaaca
    12601 gcagaccaga tttaaggaag aaggatagaa tagatatgga acagtttaaa ggaaaggttt
    12661 gggtgcttgg agatgacatt gatacagaca tcatcatccc aacagaatat ctggcacttc
    12721 caaccgtaga agatatgaaa cagtatggat tttccccact tcgtccagaa ttagcaggac
    12781 agatcggtga aggagatatt atcgtagcag gaagcaactt tggatgcggt tcttcaagag
    12841 aacaggcacc agagattatc aaagcattaa aagttaaatg cgtcattgcc aaatcatttg
    12901 cacgtatttt ctttcgtaat tccatcaata atggattact gttaattgag aatgacaaga
    12961 ttcaggatgc agttaaagaa ggcgatgaga ttgaagttac tttaggagag aagatcacat
    13021 ataatggtac agattatgag atccattccc ttccagataa cttgatggag atcatcaacg
    13081 ctggtggatt agtagaagct atgaagaaaa gaaatggggt gaaataaaga tatgggacag
    13141 acaatgattg aaaagatcat cagcagaaac gttggtgttg acagtgtaaa accaggacag
    13201 attcagacag taaatgtaga ccgtgttatg atccatgata tctttattcc attcgtagcg
    13261 gagaaattcg aagaaatggg atttacaaag ttatgggacc cagacaaagt cgtattgatc
    13321 tatgaccaca tggtaccagc aagtacaaca gacgatatca gacatttcaa gatcggtgat
    13381 gcatttgcca agaaatatgg catgaaaaat gttcacagaa gtgatgggat ctgccatcag
    13441 ttaatgacag aatgtggata tgcgaaacct gggaatatcg tattcggaac agactctcat
    13501 acaacaactt atggttgtgt tggatgtttc tcttcaggaa tcggttatac agagatggca
    13561 gcgattcttg gaacaggaga gatgtgggta agagttccag agacgatcaa agtagtcatt
    13621 gatggaaaac ttcctgaaaa tgtaagttct aaagatatta tcttacgatt gatcggagat
    13681 ttaacagcag ctggagctac ttataaagca ttagaattct ctggaagcac agttgatgag
    13741 atgagtgttg cagccagaat gacaatgtca aatatggcaa tcgaagcagg agcgaaagca
    13801 gcacttttcg caccggatga aaagacagct gaatattcta aggtagattt agctgatgtt
    13861 gattggttat atggagatga agatgctgag tattgccaga caatcacata taaagcagaa
    13921 gatttagtac cagtagtggc atgtccatca caggtagata agattagagc tgtcaaagaa
    13981 gtcgaaggaa cagagcttga tcaggtattt atcggatctt gtacaaacgg aagattagaa
    14041 gatctgaaag cggcagcaga gatcttaaaa ggaaagaaag ttgctgatta tgtaaaattg
    14101 atcgtaacac cagctagtag aaagatttat aaacaggcag tggatgctgg atacatgaag
    14161 attttggcag aagccggagc gatcatcacg catccaggat gtggattatg ttgtggacgt
    14221 gcaggtggga tcatgacaga tggagaacgt gttcttgcaa caaacaaccg taacttctta
    14281 ggaagaatgg gaacgtcaaa agtagaaatc tacttaggat cacctaagac agcagctgca
    14341 tcagcaatcg caggtaagat cgtagaagca taaagtgaac atatgaggta aagatcctca
    14401 taaatataaa gaaaaagtac attgggggtc attaggactc ccatttacta tgtagatgga
    14461 gttttttatg acaaacttat taatatcatt atttattaaa gacaaagaaa atgtaaagga
    14521 tgcaaaagta agaaatgctt atggaaagat ggcagggatt gtaggaatct gttgtaacat
    14581 cttcttattt gcaaccaaat ttttcgcagg aatcatcaca ggagcaatct ctatcacagc
    14641 agatgcgttt aacaatttat ctgatgcagc atcttctatt atcacacttg tcggatttgg
    14701 aatggctgga aaaccagcag atgaagatca tccattcgga catggaagga tggaatatgt
    14761 atcaggactt gttgtatcta tcctgatctt gatgatggga gtggaattat ttaaaacatc
    14821 agtagaaaaa gtgattcatc cagaggtgat cacagaacaa tggatttctt atgtaatatt
    14881 agtgatctcg atcgcattaa aattttggat gtatatgttt aacaaaggaa tcggatggag
    14941 aattcactct gaaacgatga aagcgacagc agcggatagt ttaaatgatt gtatttcaac
    15001 agcagcagtt gttggaggaa tgcttgtatt ccattatttt catttaaatg ttgatggaat
    15061 tgtcggaatc tttgttgcat gttttgtact ctggggtggt tatgaatcaa tcaaagatac
    15121 catgaacccc ctattaggag aatccccaga tccagaattg atcgctaaga tcacagagac
    15181 tgtattaaat cataagatgg tcatcggagt tcatgatatc gttgttcacg actatggtcc
    15241 aggaagaaga attgtctctt tgcatgcaga agttccatac aataaagata tgatggaagt
    15301 gcatgatctg atggatcata ttgaaatgcg tttgatggaa gaatatcact gcgaagcaac
    15361 aatccatatg gatcctgtag tgacggatga tgaggaagtg aatgagacaa gaaaagaagt
    15421 ttttaatatt gttaagaaat atgacaagac actgtcagtt catgactttc gaatggtcaa
    15481 agggccaaca catacgaatg tgatctttga tcttgtgatt ccttatggga aagattatga
    15541 gccagagaag atcgtgaagg atcttaagca gaagattaaa gacgagatgc aggggaaaca
    15601 ttatgcagtg attcgtgtag acagattttg atttgtagtt tgaagacgaa aattattggt
    15661 gaaannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16141 nnnnnnnnnn nnnnnacata gtgtgtgtta tgcggtattg gttaataatt tttgtattcg
    16201 ttaacagaag atgaaaggac ttaaacaaca ccgattggtc aaaatatttg aaatataaac
    16261 ttaaagatgt tgaattgata ttatatatta tataaaattt aatgaataga atattttaat
    16321 tgaataagta tatacaattt gataaaataa aaacaggtgt tacttcacat tgacgtgaat
    16381 ggcggtttgc ttcctacggg gagttctagc cccgattaca tagatcaatc tctattattg
    16441 agaaatctta cgaaaagggg gcttgaagtt atgctaacca ttacagaact aattgcagtg
    16501 atttcactgt gtgtggcttt ttatagtctt ggttatgtgt gtggaaagca tgatgccaag
    16561 atagagaaat aaccgcccat tgacctgaca agttatgtga gcggttattc aatcgtttat
    16621 atcaggcaaa ccgtcatcgg tagcaccttt tctattatta tagtaacatt tatatatttt
    16681 tatgtcaatt aagatgatta aaaatataag tgtgtgttag tatatataag atcaatgtga
    16741 ctggacagca tcttaatctt tctctaaaag ctgagcaata atcgaattag gaagtacatc
    16801 cttcaaaaca tccatacaag aaaaatcagt tctgctagtc ggcagggctt tttttgtaat
    16861 tcgaaatccc attttctgat acataccaac agccttataa gcccaagtat gtgtatgaag
    16921 aaaaataaaa tcagcatccg gttctacaac aagaaaacga gacaaagcaa acaaaacaat
    16981 tgccttccca agccccttcc cctgttcttt aggagaagta gacacccaat gaatcaaagg
    17041 aaaccgaata tcgccatttg tcttaaacca agcactcgtc gtagcaacaa tctctccctc
    17101 aggattcaca ataaaacaaa cccggtcagc taaaagttct tcatgagtta aaaaagtttt
    17161 agcaaaataa gcagaagcat cctcaaaaca atcaaactct ccaaccaaca cttcaagctt
    17221 cgcccaagca atctcatccc cagattcaaa catcttataa gaatatccat caggcaaaac
    17281 aggaacctta agatcctcta aatcctcaaa aggcagacac attacaatat ctttataaat
    17341 aagagactta tcaagcataa acaaaaaccc ccataaaatt aaaaataaca ataaattgat
    17401 taattagagt atataagcta ttgaataaaa agtcacggtg tataaattaa acagaaagta
    17461 ctttctacga atctgatttt gatagctaaa aaaattatta gacaccgatt tagcgagata
    17521 tttggaaaat cttttatctt aattcttaca agattaaaat gagagaattt cagttttcga
    17581 ttatcctgaa aatgtaaagc aatatagtaa aacatacata ctgtgaattt tgatttattg
    17641 gatttaatac annnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18061 nnnagcaaat taaaattcct cttgacactt cccttacgtc accctttatg ataacgtata
    18121 gagagaaaac caaggaggaa tctaaatgac aaaagatgga tactatacat ccggtgaatt
    18181 tgcaaaaaaa gcgaatgtaa cactaagaac gatccgctac tatgaccgtc aaggcatctt
    18241 aaagccaagt aaagttgcag acaatggata tcgtctttat acagatgccg attttgccaa
    18301 attacaaaaa atcttgtcat taaaatacct cggattttct ttggaagaga tcatgacgat
    18361 gacgatcaac gatgaagatc aggatttcat taaagaatct atcggcttac agttatacct
    18421 tgtacaaaaa aagatggaac acttaaaact ggtagagcaa tccttagaag agatggaaca
    18481 aaagatggat aatgaagaag aaatcgactg gacacagatg atgaatcttc ttcacgtaac
    18541 caatctggaa aaaggattgg tagaacaata taagaatgca tcaaatcttg atatccgtat
    18601 cggacttcat caaaaatatt cacaaaatcc acaaccatgg tttgaatgga tctatgagca
    18661 gttaaactta aaagaaaaag acgaagtatt agaactagga tgtggaacag gggaactgtg
    18721 gaagaataaa aatcttccaa aaaatgtcca tgttacttta tccgaccagt cacaaggtat
    18781 ggtaaaagat gccaggaact atgtcggaga gggaaaagga cagatttctt atcagatgat
    18841 cgactgtaga cagattccaa aagaagatca cagtttcgat aaagtgatcg caaaccatgt
    18901 attattttat ctggatgacc gacaacaagt atttaacgaa atcaaaagag ttctaaaaca
    18961 aaatggaaca tttatctgca gtacctatgg aagcagtcat atgcaggaaa ttacccagct
    19021 gatcaaagat tttgatgaaa ggatcacgct ttctgatcac aaattatata atgtctttgg
    19081 tctggaaaat ggagaagaac aattaaaaaa agtattttca caagtaaaag aaattgacta
    19141 tgaagatgaa ttgttagtcg atcagccaga accactgatc tcctatattt tatcctgtca
    19201 cggaaatcag catgaatatt taaatcatcg ttatttagaa tttaaagact ttgtaagaaa
    19261 gaagatggca gccaaaggag tgatcaagat cacaaaatct gccgggattt ttatatgtaa
    19321 accataa
//
