LOCUS       c00021_NZ_QNRX..        6614 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_QNRX01000021.1 Alkalibaculum bacchi strain DSM 22112
            Ga0244545_121, whole genome shotgun sequence.
ACCESSION   NZ_QNRX01000021
VERSION     NZ_QNRX01000021
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:37:32
            Original ID  :: NZ_QNRX01000021.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 41509
            Orig. end    :: 48123
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6614
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[46509:46929](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5420)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..6614
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6614
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     aSDomain        405..1154
                     /aSDomain="TIGR00735"
                     /aSTool="tigrfam"
                     /description="hisF: imidazoleglycerol phosphate synthase,
                     cyclase subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg21_40_0001"
                     /evalue="4.00E-110"
                     /identifier="TIGR00735"
                     /label="ctg21_40"
                     /locus_tag="ctg21_40"
                     /protein_end="250"
                     /protein_start="0"
                     /score="365.0"
                     /tool="antismash"
                     /translation="MLTKRIIPCLDVDHGRVVKGKKFKDIQDVADPVELGKYYSDQCAD
                     ELVFYDITASNEDRDIFINIVEKVAENINIPFTIGGGIRKVEDFRKVLLAGADKVSVNS
                     AAVKNPNLIKEAALKFGSQCVVLSIDAKRNDKGSWDVYVKGGRENTGIDAIEWAKRGEN
                     LGAGEICINSIDVDGVKQGYDLELNQKLSQLLNIPIIASGGAGNMSHFQEVLECGADAA
                     LAASVFHYKEIPIPDLKEYLHSKNIPVR"
     CDS             405..1169
                     /locus_tag="ctg21_40"
                     /transl_table=11
                     /translation="MLTKRIIPCLDVDHGRVVKGKKFKDIQDVADPVELGKYYSDQCAD
                     ELVFYDITASNEDRDIFINIVEKVAENINIPFTIGGGIRKVEDFRKVLLAGADKVSVNS
                     AAVKNPNLIKEAALKFGSQCVVLSIDAKRNDKGSWDVYVKGGRENTGIDAIEWAKRGEN
                     LGAGEICINSIDVDGVKQGYDLELNQKLSQLLNIPIIASGGAGNMSHFQEVLECGADAA
                     LAASVFHYKEIPIPDLKEYLHSKNIPVRRCNK"
     PFAM_domain     417..1103
                     /aSDomain="His_biosynth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00977.23"
                     /description="Histidine biosynthesis protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg21_40_0001"
                     /evalue="4.00E-83"
                     /label="ctg21_40"
                     /locus_tag="ctg21_40"
                     /protein_end="233"
                     /protein_start="4"
                     /score="278.5"
                     /tool="antismash"
                     /translation="RIIPCLDVDHGRVVKGKKFKDIQDVADPVELGKYYSDQCADELVF
                     YDITASNEDRDIFINIVEKVAENINIPFTIGGGIRKVEDFRKVLLAGADKVSVNSAAVK
                     NPNLIKEAALKFGSQCVVLSIDAKRNDKGSWDVYVKGGRENTGIDAIEWAKRGENLGAG
                     EICINSIDVDGVKQGYDLELNQKLSQLLNIPIIASGGAGNMSHFQEVLECGADAALAAS
                     VFHYKEI"
     CDS             1169..1783
                     /locus_tag="ctg21_41"
                     /transl_table=11
                     /translation="VDLSNIKYDEKGLIPAIIQDVNTNEVLMMAYMNEESLKKTMETNK
                     TWFYSRSRQNLWNKGETSGNFQDVKSISYDCDGDTLLVKVIPEGPSCHTGNNSCFFNSI
                     VEEENIANPEILKQLYKTIEDRRANPVEGSYTNYLFEKGIDKILKKVGEENAETIIAAK
                     NNSKEELIYESSDLIYHLLVLLVNQGVSLEDIFGELEKRHK"
     PFAM_domain     1250..1471
                     /aSDomain="PRA-CH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01502.20"
                     /description="Phosphoribosyl-AMP cyclohydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg21_41_0002"
                     /evalue="5.50E-35"
                     /label="ctg21_41"
                     /locus_tag="ctg21_41"
                     /protein_end="101"
                     /protein_start="27"
                     /score="119.1"
                     /tool="antismash"
                     /translation="MMAYMNEESLKKTMETNKTWFYSRSRQNLWNKGETSGNFQDVKSI
                     SYDCDGDTLLVKVIPEGPSCHTGNNSCFF"
     aSDomain        1514..1765
                     /aSDomain="TIGR03188"
                     /aSTool="tigrfam"
                     /description="histidine_hisI: phosphoribosyl-ATP
                     diphosphatase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg21_41_0002"
                     /evalue="2.50E-34"
                     /identifier="TIGR03188"
                     /label="ctg21_41"
                     /locus_tag="ctg21_41"
                     /protein_end="199"
                     /protein_start="115"
                     /score="115.3"
                     /tool="antismash"
                     /translation="LKQLYKTIEDRRANPVEGSYTNYLFEKGIDKILKKVGEENAETII
                     AAKNNSKEELIYESSDLIYHLLVLLVNQGVSLEDIFGEL"
     PFAM_domain     1514..1777
                     /aSDomain="PRA-PH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01503.19"
                     /description="Phosphoribosyl-ATP pyrophosphohydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg21_41_0003"
                     /evalue="3.80E-19"
                     /label="ctg21_41"
                     /locus_tag="ctg21_41"
                     /protein_end="203"
                     /protein_start="115"
                     /score="69.0"
                     /tool="antismash"
                     /translation="LKQLYKTIEDRRANPVEGSYTNYLFEKGIDKILKKVGEENAETII
                     AAKNNSKEELIYESSDLIYHLLVLLVNQGVSLEDIFGELEKRH"
     CDS             complement(1940..2140)
                     /locus_tag="ctg21_42"
                     /transl_table=11
                     /translation="MKALGTTLLNCFLLVISLLAHRILVRSFNLPINDALFYWGLLIAI
                     FGINSLIFALILSSERENNHR"
     CDS             complement(2156..2773)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 168.9; E-value:
                     2.4e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_43"
                     /transl_table=11
                     /translation="MIELANVSKAFEGQIVLNDFSVKIETNEFVTIVGKSGSGKSTLLH
                     IMSMIDKPNSGTVRFLDWTNPKGKDLLELRRCHFGYVFQNYVLMNNKTVKENLLLSTKY
                     TSSKDPAALVDYLEKVQLSKEYLNKKVYQLSGGEQQRLAIARILLKPCTTIFADEPTGN
                     LDNYNKNIILSLFKELKAEGKTIICATHDREIANQSDRTISL"
     PFAM_domain     complement(2291..2725)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg21_43_0004"
                     /evalue="1.00E-29"
                     /label="ctg21_43"
                     /locus_tag="ctg21_43"
                     /protein_end="161"
                     /protein_start="16"
                     /score="103.9"
                     /tool="antismash"
                     /translation="LNDFSVKIETNEFVTIVGKSGSGKSTLLHIMSMIDKPNSGTVRFL
                     DWTNPKGKDLLELRRCHFGYVFQNYVLMNNKTVKENLLLSTKYTSSKDPAALVDYLEKV
                     QLSKEYLNKKVYQLSGGEQQRLAIARILLKPCTTIFADEPT"
     CDS             complement(2770..4950)
                     /locus_tag="ctg21_44"
                     /transl_table=11
                     /translation="MKKTIFLFSFILFLLSILIFEFDFAFQKYSYDIVAGNHQEIHIVY
                     HQETSLDDIINALKQFSIDHNVNISQYTFLDEETIHIYSTYLPADSGIRLIHGMYPKGG
                     EFISNKQTTENPQSGYISSPPTQLDYKFYSIDQINNVGLRGDFYMASSDLELARALEKI
                     LYPLGDVQIAPVQVNLAYFVNVSLLLLVFFTFIIYIITVLFYVFSENKSIYLEQLWGYS
                     SKEIFLRLLTPFFKPIACIIGVLVSVLAIFIIYYQQIHFVIVYLALFILAVLISLIVGA
                     AISLMTLKMICQSGLSSVDLKEKLPFKNYAMASVIIKFVVTFVFLMINVFSIHTLLNLN
                     KQLKTTEYWEVTKDIYQVTAKYSDTSNDLVKERARNNCLSDFYNALNEEKSAILIEAQN
                     FSNMSTDVNHPKYLYELNTNDNLSASISTGGRNITINQNYLDFNPIISVNGNNAKEEIK
                     YDRDTLILLVPEKLQQYEEKIQENFRELFYFQRVEIANMYNKEAGQALDTTSIDDLHVH
                     IIYVKNNQEYFPFYTDLGDLDNNNMVVDPIAIIYHPTVDTSFIAAYVTSSLYFVDTHKG
                     EAYTSLKEILVGTDALQYIPSVISVYQEKGKEISALKQKIVQQITALILMLIISICCII
                     VFAWCYYIPNAKTMYLRLLFGYSHWYRNKKMYLTVLITNMIAGIAVYMAFLSIISVYAI
                     VVLLLFDIFITFFMEKMLQEKYKSAILKGDSL"
     PFAM_domain     complement(2782..3081)
                     /aSDomain="DUF1430"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07242.13"
                     /description="Protein of unknown function (DUF1430)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg21_44_0005"
                     /evalue="8.60E-09"
                     /label="ctg21_44"
                     /locus_tag="ctg21_44"
                     /protein_end="723"
                     /protein_start="623"
                     /score="35.7"
                     /tool="antismash"
                     /translation="ILMLIISICCIIVFAWCYYIPNAKTMYLRLLFGYSHWYRNKKMYL
                     TVLITNMIAGIAVYMAFLSIISVYAIVVLLLFDIFITFFMEKMLQEKYKSAILKG"
     aSDomain        complement(2782..4905)
                     /aSDomain="TIGR01654"
                     /aSTool="tigrfam"
                     /description="bact_immun_7tm: bacteriocin-associated
                     integral membrane protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg21_44_0003"
                     /evalue="3.70E-63"
                     /identifier="TIGR01654"
                     /label="ctg21_44"
                     /locus_tag="ctg21_44"
                     /protein_end="723"
                     /protein_start="15"
                     /score="212.0"
                     /tool="antismash"
                     /translation="SILIFEFDFAFQKYSYDIVAGNHQEIHIVYHQETSLDDIINALKQ
                     FSIDHNVNISQYTFLDEETIHIYSTYLPADSGIRLIHGMYPKGGEFISNKQTTENPQSG
                     YISSPPTQLDYKFYSIDQINNVGLRGDFYMASSDLELARALEKILYPLGDVQIAPVQVN
                     LAYFVNVSLLLLVFFTFIIYIITVLFYVFSENKSIYLEQLWGYSSKEIFLRLLTPFFKP
                     IACIIGVLVSVLAIFIIYYQQIHFVIVYLALFILAVLISLIVGAAISLMTLKMICQSGL
                     SSVDLKEKLPFKNYAMASVIIKFVVTFVFLMINVFSIHTLLNLNKQLKTTEYWEVTKDI
                     YQVTAKYSDTSNDLVKERARNNCLSDFYNALNEEKSAILIEAQNFSNMSTDVNHPKYLY
                     ELNTNDNLSASISTGGRNITINQNYLDFNPIISVNGNNAKEEIKYDRDTLILLVPEKLQ
                     QYEEKIQENFRELFYFQRVEIANMYNKEAGQALDTTSIDDLHVHIIYVKNNQEYFPFYT
                     DLGDLDNNNMVVDPIAIIYHPTVDTSFIAAYVTSSLYFVDTHKGEAYTSLKEILVGTDA
                     LQYIPSVISVYQEKGKEISALKQKIVQQITALILMLIISICCIIVFAWCYYIPNAKTMY
                     LRLLFGYSHWYRNKKMYLTVLITNMIAGIAVYMAFLSIISVYAIVVLLLFDIFITFFME
                     KMLQEKYKSAILKG"
     CDS             complement(5001..5420)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_45"
                     /sec_met_domain="Lactococcin_972 (E-value: 1.7e-11,
                     bitscore: 36.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLILKKTLASVLFAVALFVLPVSTTLASSIEGGSDGINQGTFDYD
                     TNTYTEIINDRFIGNDNSITPLTTEYVGGGKWEHGFIGIEWVYSNYNHVEKTHKSSASN
                     SIRTVDSGWKLKTDGWAKAKAAQTLWGNKANWNTK"
     aSDomain        complement(5004..5390)
                     /aSDomain="TIGR01653"
                     /aSTool="tigrfam"
                     /description="lactococcin_972: bacteriocin, lactococcin 972
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg21_45_0004"
                     /evalue="4.90E-12"
                     /identifier="TIGR01653"
                     /label="ctg21_45"
                     /locus_tag="ctg21_45"
                     /protein_end="139"
                     /protein_start="10"
                     /score="44.0"
                     /tool="antismash"
                     /translation="VLFAVALFVLPVSTTLASSIEGGSDGINQGTFDYDTNTYTEIIND
                     RFIGNDNSITPLTTEYVGGGKWEHGFIGIEWVYSNYNHVEKTHKSSASNSIRTVDSGWK
                     LKTDGWAKAKAAQTLWGNKANWNTK"
     PFAM_domain     complement(5013..5204)
                     /aSDomain="Lactococcin_972"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09683.12"
                     /description="Bacteriocin (Lactococcin_972)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg21_45_0006"
                     /evalue="5.20E-11"
                     /label="ctg21_45"
                     /locus_tag="ctg21_45"
                     /protein_end="136"
                     /protein_start="72"
                     /score="43.0"
                     /tool="antismash"
                     /translation="GGGKWEHGFIGIEWVYSNYNHVEKTHKSSASNSIRTVDSGWKLKT
                     DGWAKAKAAQTLWGNKANW"
     CDS             5486..5683
                     /locus_tag="ctg21_46"
                     /transl_table=11
                     /translation="MLAKTELEDSTIKKANNNKYNFFTQSFFSIFLKSYHIKTVTICRI
                     LGKMSIKLDFKVGISDLEYN"
     CDS             complement(5826..6545)
                     /locus_tag="ctg21_47"
                     /transl_table=11
                     /translation="VVCFECNTQGYQIIQNIDHFRYGTDAVLLSWYVACKVYSKSHIID
                     IGTGTGIIPILLAANNVGESIDALEIQDYYADLARRNIKLNKLDHKINVFHGDMRFLPE
                     EIIKKKYDAVISNPPYMRKSIHSSNEALAIARHEITWSMQEFMKSASKIMKDKGKCILI
                     HRADRIVDIFYYMRLHSIEPKSMRLIYPKKGKNANLVLVEGVKNGKPQLTNEEPLIIYG
                     DDGGYTDEVLRIYYGRL"
     PFAM_domain     complement(6054..6431)
                     /aSDomain="MTS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05175.16"
                     /description="Methyltransferase small domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg21_47_0007"
                     /evalue="1.70E-13"
                     /label="ctg21_47"
                     /locus_tag="ctg21_47"
                     /protein_end="164"
                     /protein_start="38"
                     /score="50.6"
                     /tool="antismash"
                     /translation="SKSHIIDIGTGTGIIPILLAANNVGESIDALEIQDYYADLARRNI
                     KLNKLDHKINVFHGDMRFLPEEIIKKKYDAVISNPPYMRKSIHSSNEALAIARHEITWS
                     MQEFMKSASKIMKDKGKCILIH"
ORIGIN
        1 gggaaaagct ttgtatgagg gggcgcttac tatggaggaa ataaatgcag ttctaggttc
       61 tacgttgtaa gttctaagta aaagctatga ggtgactaga taattgctga tgggttgatc
      121 agttggttcg ttggacggtt ggacgggaaa aagctttaaa gcggaaagcg gaacttttcg
      181 tatttagttt tttgctttat agattttatg tggcgtgtag tttgtatagt gagatccttc
      241 gcttcgctcc aggatgactc ctgacggagc ttaagctttt tctcaccgaa ggtgagttgg
      301 cttttgctga ccacctgacc acccgaccag ctgaccacct cataactgat aacgcataat
      361 taaatacaac acttcactac tttataaata aggaggtacc aactatgcta accaaaagaa
      421 tcattccctg tttagatgta gatcacggta gagtcgtcaa gggaaagaag tttaaggaca
      481 ttcaagatgt agcggatcct gttgagttag gcaaatatta ttcagaccaa tgtgcagatg
      541 agctggtctt ttatgatatt acagcctcta atgaagatag agatattttt ataaatattg
      601 tagaaaaggt agcagaaaac atcaatatcc cctttacaat aggtggtggc atacgaaagg
      661 tagaggactt taggaaagtg ctcttagcag gagcagataa ggtgtctgta aactctgcag
      721 cagtaaaaaa ccctaatctt attaaagaag cagctttaaa atttggaagt caatgcgtag
      781 tcctctccat tgacgctaaa agaaatgata aaggctcttg ggatgtatat gtaaaaggcg
      841 gtcgagaaaa cacgggtatt gatgctattg agtgggcaaa acgtggagaa aacttaggtg
      901 caggagaaat ttgcattaac tctattgatg tagacggagt aaagcagggt tatgatcttg
      961 aattaaatca aaaattatct caactcctaa atatccctat tatcgcctct ggtggagcag
     1021 gaaatatgtc tcactttcaa gaggtactag agtgcggtgc agacgctgca ctagctgcct
     1081 ctgtctttca ctataaagaa atacctatac cagatttaaa agagtactta cacagtaaaa
     1141 atatacccgt taggagatgt aataaatagt ggatctatcc aatataaaat acgatgaaaa
     1201 gggattaatt cctgcaatca tacaagatgt aaacacaaat gaagtactaa tgatggcata
     1261 catgaacgaa gaatctttga agaagaccat ggaaacgaat aaaacgtggt tttacagtag
     1321 aagcagacaa aacctttgga acaaggggga aacctcagga aactttcaag atgtaaagag
     1381 tatttcctat gactgcgatg gcgatacact cttagttaaa gtaatacctg aaggaccaag
     1441 ttgtcataca ggcaataatt catgcttttt taatagcatt gtagaagaag agaacatagc
     1501 aaaccctgaa atattaaaac agttatacaa aactatagaa gatcgaaggg caaatcccgt
     1561 agagggatct tatacaaact acttatttga aaaaggtata gataaaatcc ttaaaaaagt
     1621 aggggaagaa aatgcagaaa ccataattgc cgctaaaaac aattctaaag aagagttaat
     1681 ctacgaatct tcagatttaa tttatcatct attagttctc ttagtaaatc aaggagtatc
     1741 tttagaggat atctttggag aattggaaaa gagacataaa taggaagtag gcgatcaatc
     1801 accaacctcg tactagatct ataatctaaa atttcttttt ataaactcaa aatgagaaat
     1861 cagtccatga gcctagtgac gacagcagct tatggacttt tggttttgca aacatacacc
     1921 atagtatagt attacctatt tatcgatgat tattttctct ctctgatgat aaaattaatg
     1981 cgaatattaa actatttata ccaaaaatag caataagtag cccccaataa aagagagcat
     2041 cgttaatcgg aagattaaat gaccttacta gtatccggtg tgcaagtaaa gaaatcacta
     2101 ataaaaaaca atttaataat gttgttccta aagccttcat atcaattcct ccatcttaaa
     2161 gtgatattgt tctatctgat tggtttgcaa tctctctgtc atgcgttgca cagatgatgg
     2221 tttttccttc tgcctttaat tctttaaata gagataaaat aatattttta ttataattat
     2281 ccaaatttcc tgtaggctca tctgcaaata tggtagtaca tggctttaat aatatccgtg
     2341 caatagctaa tctctgttgt tctccgccgc ttaattgata cactttctta tttaaatatt
     2401 ctttacttaa ttgtaccttt tctaaataat ctaccagagc tgctggatct ttagaggagg
     2461 tgtatttggt agaaagcagg agattttcct ttaccgtctt gttattcatt aaaacataat
     2521 tttggaatac atatccaaaa tggcatcttc ttagctctaa taaatccttt ccttttggat
     2581 tcgtccagtc taagaatctc acggttccag aattaggctt atcgatcata ctcattatat
     2641 gtagtaaagt agattttcca cttccgcttt ttccaacaat tgtgacaaat tcatttgtct
     2701 ctatttttac agaaaaatca tttaaaacaa tctggccctc aaaggctttt gatacattgg
     2761 ctaattcgat catagagagt ctccttttaa aattgcgctc ttatatttct cttgaagcat
     2821 tttttccatg aaaaaagtaa taaaaatgtc aaacaacagt aatacgacaa tggcatatac
     2881 cgatattata gacaaaaatg ccatatatac tgcgataccg gcaatcatat ttgttatcaa
     2941 tacggttaag tacatttttt tattgcgata ccaatgagaa taaccgaata aaaggcgaag
     3001 atacatggtt tttgcattcg gaatatagta acaccacgca aaaacaataa tacaacagat
     3061 ggatataatc aacattaaaa tcagcgccgt aatttgctga acaatttttt gttttaatgc
     3121 tgaaatttct ttccctttct cttgatacac agaaatgaca ctggggatat actgtaatgc
     3181 atccgtgccc accaagatct ctttcaggga ggtataggct tcccccttat gcgtatccac
     3241 aaaatataag ctggacgtta cataagcagc aatgaaagat gtatctactg taggatgata
     3301 gatgatggca ataggatcca ccaccatatt gttgttgtcc aggtctccaa gatcagtata
     3361 aaaaggaaag tattcctgat tgttttttac atatataata tgtacatgta aatcatcgat
     3421 tgatgttgtg tcaagggctt gtcctgcctc tttattgtac atattggcta tttctacacg
     3481 ttgaaaatag aataattctc ggaagttttc ttggattttc tcttcatatt gctggagttt
     3541 ttccggcacc aatagaatca aggtatcccg gtcgtacttg atttcctctt tggcattgtt
     3601 cccattgacg ctaataatgg gattaaaatc taaatagttt tgatttattg ttatattgcg
     3661 ccctccagta gatatggatg cactgagatt atcatttgta ttgagttcat atagatattt
     3721 gggatgattc acatctgtac tcatattgga aaagttttgt gcttcgatga gaatagcgga
     3781 tttctcttca tttagtgcat tataaaaatc agataggcaa ttattccgtg cgcgctcctt
     3841 aactaaatcg ttcgatgtat ccgaatactt tgccgtaacc tgatatatat ccttcgttac
     3901 ttcccagtat tcagtcgttt ttagctgttt atttaaattg agtaaagtat gaatggaaaa
     3961 tacattaatc atcaaaaaaa caaaggtcac tacaaacttg atgattacag aggccattgc
     4021 atagttttta aagggaagct tttcttttaa atctacactg ctcagaccgg attgacagat
     4081 catctttagt gtcatgagag atatggccgc ccctacaata agactaataa gaactgccaa
     4141 gataaataaa gccaaataga ctatgacaaa atggatttgt tgataataaa ttataaagat
     4201 agccaacaca gacactagaa cacctataat acaagcaatg ggcttgaaaa aaggggttaa
     4261 gagtctcaaa aagatctcct tagacgaata cccccacaat tgctctaagt atatggattt
     4321 attctcacta aatacataaa acaaaaccgt aattatatag attataaaag taaagaaaac
     4381 tagcaatagc aagcttacat ttacaaaata tgctaaattt acttgaacgg gtgcaatttg
     4441 aacatcaccg agagggtata aaatcttttc caatgctcta gccagctcca gatcagaaga
     4501 ggccatataa aagtcacccc tcagccccac gttattaatc tgatcaatcg aataaaactt
     4561 ataatcaagc tgtgtgggtg gagaagaaat gtatccagac tgcggattct ccgtagtttg
     4621 cttattggaa ataaactccc ctcctttggg atacattcca tgaattaacc gtattccgga
     4681 atctgccggt aaatacgtcg aatatatatg tattgtctct tcatcaagga aggtatactg
     4741 agaaatattt acattatggt ctattgaaaa ttgttttaat gcatttataa tatcatctag
     4801 tgatgtttcc tgatgatata caatatgaat ctcttgatga ttgcctgcta ctatatcgta
     4861 cgaatatttt tgaaatgcaa aatcgaactc aaatattaaa atagacaaga gaaataatat
     4921 aaaagaaaat agaaaaatcg tttttttcat atagacacct caaataaaca ggcttgctga
     4981 acacaagcct gtcctacata ttactttgta ttccaatttg ccttatttcc ccataaggtt
     5041 tgtgcagctt tagcttttgc ccatccatca gttttcaatt tccatcctga atccactgta
     5101 cgaattgaat tacttgcact agacttatgt gttttttcga cgtgattata attagaataa
     5161 acccattcaa tccctataaa gccatgttcc cattttcctc cacctacata ttctgttgta
     5221 agaggtgtga tagaattatc attaccaata aaacgatcgt ttatgatctc agtgtatgta
     5281 ttcgtatcgt agtcaaacgt tccttgatta atgccatcac ttcctccttc aatactagac
     5341 gccaatgtag ttgatacagg aagcacaaat agtgctactg caaacaatac tgaagctaat
     5401 gttttcttca atataagcat cacctttcaa attttatatt tttataatta aagagtctat
     5461 aaaactccaa aattaacatt gtttaatgtt agcaaagacg gaattagaag atagtactat
     5521 taaaaaggct aacaataaca aatataactt tttcactcaa tcattctttt ccatattttt
     5581 aaaatcttac catattaaaa ctgtaacaat ttgtcgaata ttaggaaaaa tgtcaataaa
     5641 actcgatttt aaggtaggga tttccgattt agaatataat taattttaat tatgtattat
     5701 attatttttg ttattcatca tttgctttta aagcccggaa acaatataat ccgatacata
     5761 ataagggcga acacagctcg cccctacgct accttactac gttatcacct taacaccttt
     5821 ccaacttata atcgcccata atatatcctc aacacttcat ctgtgtaccc tccatcatct
     5881 ccataaataa tgaggggctc ttcattggtc agctgtggct ttccgttttt tactccctct
     5941 actaaaacta aattagcatt tttccccttt ttaggataga taagccgcat acttttaggt
     6001 tcaatagaat gtagcctcat atagtaaaaa atatctacaa ttcgatctgc cctatgaata
     6061 aggatgcact ttcctttatc tttcataatt ttactagccg atttcataaa ctcctgcata
     6121 gaccaggtaa tttcatgtct ggcaatggct agggcttcat ttgaactgtg aatgctcttc
     6181 ctcatatagg gtgggttgga gatgactgca tcgtatttct tttttataat ttcttctggc
     6241 aagaatctca tatcaccgtg aaatacatta attttatgat ctaatttatt taattttata
     6301 tttcttcttg ctaaatcagc ataataatcc tgaatctcta gagcatctat agactctccc
     6361 acattatttg cagctaagag aataggtatt attccagtcc cagtaccaat atctataata
     6421 tggcttttac tatatacttt acaagctaca taccaactaa gaagtacagc atctgtacca
     6481 tatctaaaat gatctatatt ctgtattatt tgataaccct gagtattgca ttcgaaacag
     6541 accacaagtg catatattta gaccacctag tgcattaaaa cagaccactc agtgcattgc
     6601 agtagaccag agct
//
