Select genomic region:
Overview
5.1
5.2
5.3
6.1
8.1
10.1
11.1
11.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_ATVI01000005 (original name was: NZ_ATVI01000005.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | betalactone | 548 | 23,297 |
Region 5.2 | redox-cofactor | 340,800 | 363,030 |
Region 5.3 | hglE-KS | 712,346 | 766,660 | neomycin | Saccharide | 5%

NZ_ATVI01000006 (original name was: NZ_ATVI01000006.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 6.1 | RiPP-like | 779,898 | 790,788 |

NZ_ATVI01000008 (original name was: NZ_ATVI01000008.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 8.1 | terpene | 192,519 | 213,640 | carotenoid | Terpene | 100%

NZ_ATVI01000010 (original name was: NZ_ATVI01000010.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 10.1 | RiPP-like | 100,137 | 110,985 |

NZ_ATVI01000011 (original name was: NZ_ATVI01000011.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 11.1 | tropodithietic-acid | 14,521 | 36,018 |
Region 11.2 | terpene | 202,460 | 225,657 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | betalactone | 548 | 23,297 |
Region 5.2 | redox-cofactor | 340,800 | 363,030 |
Region 5.3 | hglE-KS | 712,346 | 766,660 | neomycin | Saccharide | 5%
Region 6.1 | RiPP-like | 779,898 | 790,788 |
Region 8.1 | terpene | 192,519 | 213,640 | carotenoid | Terpene | 100%
Region 10.1 | RiPP-like | 100,137 | 110,985 |
Region 11.1 | tropodithietic-acid | 14,521 | 36,018 |
Region 11.2 | terpene | 202,460 | 225,657 |

No secondary metabolite regions were found in these records:
  NZ_ATVI01000001 (original name was: NZ_ATVI01000001.1)
  NZ_ATVI01000002 (original name was: NZ_ATVI01000002.1)
  NZ_ATVI01000003 (original name was: NZ_ATVI01000003.1)
  NZ_ATVI01000004 (original name was: NZ_ATVI01000004.1)
  NZ_ATVI01000007 (original name was: NZ_ATVI01000007.1)
  NZ_ATVI01000009 (original name was: NZ_ATVI01000009.1)
  NZ_ATVI01000012 (original name was: NZ_ATVI01000012.1)
  NZ_ATVI01000013 (original name was: NZ_ATVI01000013.1)

Compact view
c00005_NZ_ATVI.. - Region 1 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 548 - 23,297 nt. (total: 22,750 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001605.1 |  | 0.15 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000698.1 |  | 0.15 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0001343.1 |  | 0.15 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001615.1 |  | 0.15 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001138.1 |  | 0.15 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0001987.1 |  | 0.14 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0001917.1 |  | 0.14 | Polyketide | 5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals | Streptomyces nigrescens
BGC0000894.1 |  | 0.14 | Other | citrinin | Monascus aurantiacus
BGC0000010.1 |  | 0.14 | Polyketide | aflatoxin | Aspergillus flavus
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001605.1 |  | 0.46 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000698.1 |  | 0.45 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0001343.1 |  | 0.45 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001615.1 |  | 0.45 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001138.1 |  | 0.45 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0001987.1 |  | 0.44 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0001917.1 |  | 0.44 | Polyketide | 5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals | Streptomyces nigrescens
BGC0000894.1 |  | 0.43 | Other | citrinin | Monascus aurantiacus
BGC0000010.1 |  | 0.43 | Polyketide | aflatoxin | Aspergillus flavus
BGC0001783.1 |  | 0.43 | Other | streptonigrin | Streptomyces flocculus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_ATVI.. - Region 2 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 340,800 - 363,030 nt. (total: 22,231 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001645.1 |  | 0.23 | RiPP | lagmysin | Streptomyces sp. NRRL S-118
BGC0000601.1 |  | 0.23 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000602.1 |  | 0.23 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001655.1 |  | 0.21 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0001779.1 |  | 0.21 | RiPP | siamycin | Streptomyces nodosus
BGC0001549.1 |  | 0.20 | RiPP | citrulassin B | Streptomyces aurantiacus JA 4570
BGC0001496.1 |  | 0.20 | RiPP | actinokineosin | Actinokineospora spheciospongiae
BGC0002015.1 |  | 0.20 | RiPP | aborycin | Streptomyces sp. ZS0098
BGC0001634.1 |  | 0.20 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0001551.1 |  | 0.20 | RiPP | citrulassin E | Streptomyces glaucescens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001645.1 |  | 0.56 | RiPP | lagmysin | Streptomyces sp. NRRL S-118
BGC0000601.1 |  | 0.56 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000602.1 |  | 0.56 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001655.1 |  | 0.53 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0001779.1 |  | 0.53 | RiPP | siamycin | Streptomyces nodosus
BGC0001549.1 |  | 0.53 | RiPP | citrulassin B | Streptomyces aurantiacus JA 4570
BGC0001496.1 |  | 0.53 | RiPP | actinokineosin | Actinokineospora spheciospongiae
BGC0002015.1 |  | 0.53 | RiPP | aborycin | Streptomyces sp. ZS0098
BGC0001634.1 |  | 0.53 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0001551.1 |  | 0.53 | RiPP | citrulassin E | Streptomyces glaucescens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_ATVI.. - Region 3 - hglE-KS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 712,346 - 766,660 nt. (total: 54,315 nt) Show pHMM detection rules used
hglE-KS: (hglE or hglD)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hglE-KS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000861.1 |  | 0.31 | Other | eicosapentaenoic acid | Shewanella sp. BR-2
BGC0000862.1 |  | 0.31 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0000869.1 |  | 0.28 | Other | heterocyst glycolipids | Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0000863.1 |  | 0.28 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0001872.1 |  | 0.26 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0000284.1 |  | 0.25 | Polyketide | phenolic lipids | Azotobacter vinelandii DJ
BGC0000864.1 |  | 0.25 | Other | eicosapentaenoic acid-like compound | Moritella marina ATCC 15381
BGC0000140.1 |  | 0.24 | Polyketide | 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one | Streptomyces sp. 88-682
BGC0001338.1 |  | 0.24 | Polyketide | citrinin | Monascus ruber
BGC0000056.1 |  | 0.24 | Polyketide | esperamicin | Actinomadura verrucosospora

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000861.1 |  | 0.65 | Other | eicosapentaenoic acid | Shewanella sp. BR-2
BGC0000862.1 |  | 0.64 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0000869.1 |  | 0.62 | Other | heterocyst glycolipids | Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0000863.1 |  | 0.61 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0001872.1 |  | 0.59 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0000284.1 |  | 0.58 | Polyketide | phenolic lipids | Azotobacter vinelandii DJ
BGC0000864.1 |  | 0.58 | Other | eicosapentaenoic acid-like compound | Moritella marina ATCC 15381
BGC0000140.1 |  | 0.58 | Polyketide | 4-hexadecanoyl-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-one | Streptomyces sp. 88-682
BGC0001338.1 |  | 0.57 | Polyketide | citrinin | Monascus ruber
BGC0000056.1 |  | 0.57 | Polyketide | esperamicin | Actinomadura verrucosospora

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 712345 - 766660:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (mal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg5_643: mxmal
  PKS_AT (577..892): mxmal
  ATSignature: (unknown)
  No matches above 50%
  minowa: Methoxymalonyl-CoA
  Prediction, score:
    Methoxymalonyl-CoA: 21.7
    Methylmalonyl-CoA: 12.0
    Malonyl-CoA: 7.0
    trans-1,2-CPDA: 0.0
    inactive: 0.0
    fatty_acid: 0.0
    Propionyl-CoA: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0
ctg5_644: mal
  PKS_AT (1253..1551): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 70.8%
    inactive: 62.5%
    Methylmalonyl-CoA: 54.2%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 77.3
    Methylmalonyl-CoA: 34.5
    inactive: 29.5
    Methoxymalonyl-CoA: 28.2
    fatty_acid: 15.1
    Ethylmalonyl-CoA: 13.8
    CHC-CoA: 12.4
    2-Methylbutyryl-CoA: 11.4
    Propionyl-CoA: 11.3
    Isobutyryl-CoA: 10.4
    trans-1,2-CPDA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0

c00006_NZ_ATVI.. - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 779,898 - 790,788 nt. (total: 10,891 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000813.1 |  | 0.06 | Alkaloid | K-252a | Nonomuraea longicatena
BGC0001427.1 |  | 0.06 | NRP, Polyketide | myxochromide A | Myxococcus xanthus
BGC0001425.1 |  | 0.06 | NRP, Polyketide | myxochromide A | Myxococcus xanthus DK 1622
BGC0001426.1 |  | 0.05 | NRP, Polyketide | myxochromide A | Myxococcus xanthus
BGC0001424.1 |  | 0.05 | NRP, Polyketide | myxochromide C | Myxococcus virescens
BGC0001423.1 |  | 0.05 | NRP, Polyketide | myxochromide C | Myxococcus hansupus
BGC0001421.1 |  | 0.05 | NRP, Polyketide | myxochromide B | Myxococcus sp.
BGC0001428.1 |  | 0.05 | NRP, Polyketide | myxochromide A | Myxococcus xanthus
BGC0001472.1 |  | 0.05 | RiPP | berninamycin A | Streptomyces bernensis
BGC0000615.1 |  | 0.05 | RiPP | TP-1161 | Nocardiopsis sp. TFS65-07

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000813.1 |  | 0.26 | Alkaloid | K-252a | Nonomuraea longicatena
BGC0001427.1 |  | 0.24 | NRP, Polyketide | myxochromide A | Myxococcus xanthus
BGC0001425.1 |  | 0.24 | NRP, Polyketide | myxochromide A | Myxococcus xanthus DK 1622
BGC0001426.1 |  | 0.24 | NRP, Polyketide | myxochromide A | Myxococcus xanthus
BGC0001424.1 |  | 0.24 | NRP, Polyketide | myxochromide C | Myxococcus virescens
BGC0001423.1 |  | 0.24 | NRP, Polyketide | myxochromide C | Myxococcus hansupus
BGC0001421.1 |  | 0.24 | NRP, Polyketide | myxochromide B | Myxococcus sp.
BGC0001428.1 |  | 0.24 | NRP, Polyketide | myxochromide A | Myxococcus xanthus
BGC0001472.1 |  | 0.23 | RiPP | berninamycin A | Streptomyces bernensis
BGC0000615.1 |  | 0.22 | RiPP | TP-1161 | Nocardiopsis sp. TFS65-07

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00008_NZ_ATVI.. - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 192,519 - 213,640 nt. (total: 21,122 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.51 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000656.1 |  | 0.25 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000648.1 |  | 0.23 | Terpene | carotenoid | Myxococcus xanthus
BGC0000650.1 |  | 0.21 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000646.1 |  | 0.21 | Terpene | β-carotein | uncultured bacterium
BGC0000630.1 |  | 0.20 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000645.1 |  | 0.20 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000664.1 |  | 0.19 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000641.1 |  | 0.19 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000638.1 |  | 0.19 | Terpene | carotenoid | Pantoea ananatis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.79 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000656.1 |  | 0.58 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000648.1 |  | 0.57 | Terpene | carotenoid | Myxococcus xanthus
BGC0000650.1 |  | 0.54 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000646.1 |  | 0.53 | Terpene | β-carotein | uncultured bacterium
BGC0000630.1 |  | 0.53 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000645.1 |  | 0.52 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000664.1 |  | 0.51 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000641.1 |  | 0.51 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000638.1 |  | 0.50 | Terpene | carotenoid | Pantoea ananatis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00010_NZ_ATVI.. - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 100,137 - 110,985 nt. (total: 10,849 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000820.1 |  | 0.14 | Alkaloid | physostigmine | Streptomyces griseofuscus
BGC0002009.1 |  | 0.14 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0000010.1 |  | 0.13 | Polyketide | aflatoxin | Aspergillus flavus
BGC0001586.1 |  | 0.13 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000005.1 |  | 0.13 | Polyketide | aflatoxin | Aspergillus parasiticus
BGC0000043.1 |  | 0.11 | Polyketide | curacin A | Moorea producens 19L
BGC0001486.1 |  | 0.09 | RiPP | 3-thiaglutamate | Pseudomonas syringae pv. maculicola str. ES4326
BGC0002027.1 |  | 0.09 | RiPP | TglA-thiaGlu | Pseudomonas syringae pv. maculicola str. ES4326
BGC0000582.1 |  | 0.08 | RiPP | cypemycin | Streptomyces sp. OH-4156
BGC0001417.1 |  | 0.07 | NRP, Polyketide | myxochromide D | Cystobacterineae bacterium

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000820.1 |  | 0.43 | Alkaloid | physostigmine | Streptomyces griseofuscus
BGC0002009.1 |  | 0.43 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0000010.1 |  | 0.42 | Polyketide | aflatoxin | Aspergillus flavus
BGC0001586.1 |  | 0.42 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000005.1 |  | 0.42 | Polyketide | aflatoxin | Aspergillus parasiticus
BGC0000043.1 |  | 0.38 | Polyketide | curacin A | Moorea producens 19L
BGC0001486.1 |  | 0.34 | RiPP | 3-thiaglutamate | Pseudomonas syringae pv. maculicola str. ES4326
BGC0002027.1 |  | 0.34 | RiPP | TglA-thiaGlu | Pseudomonas syringae pv. maculicola str. ES4326
BGC0000582.1 |  | 0.30 | RiPP | cypemycin | Streptomyces sp. OH-4156
BGC0001417.1 |  | 0.29 | NRP, Polyketide | myxochromide D | Cystobacterineae bacterium

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
c00011_NZ_ATVI.. - Region 1 - tropodithietic-acid
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 14,521 - 36,018 nt. (total: 21,498 nt) Show pHMM detection rules used
tropodithietic-acid: ((GST_N_3 or GST_C) and (Acyl-CoA_dh_N or Acyl-CoA_dh_M or Acyl-CoA_dh_1) and TIGR02278)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | tropodithietic-acid | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002000.1 |  | 0.22 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001723.1 |  | 0.21 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000231.1 |  | 0.20 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.20 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000228.1 |  | 0.19 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002016.1 |  | 0.19 | Polyketide | lugdunomycin | Streptomyces sp. QL37
BGC0000236.1 |  | 0.19 | Polyketide | kinamycin | Streptomyces murayamaensis
BGC0001177.1 |  | 0.19 | Polyketide | mensacaricin | Streptomyces bottropensis
BGC0001904.1 |  | 0.19 | Polyketide | fluostatin | Micromonospora rosaria
BGC0000221.1 |  | 0.18 | Polyketide | erdacin | uncultured soil bacterium V167

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002000.1 |  | 0.55 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001723.1 |  | 0.53 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000231.1 |  | 0.53 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.52 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000228.1 |  | 0.52 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002016.1 |  | 0.52 | Polyketide | lugdunomycin | Streptomyces sp. QL37
BGC0000236.1 |  | 0.51 | Polyketide | kinamycin | Streptomyces murayamaensis
BGC0001177.1 |  | 0.51 | Polyketide | mensacaricin | Streptomyces bottropensis
BGC0001904.1 |  | 0.51 | Polyketide | fluostatin | Micromonospora rosaria
BGC0000221.1 |  | 0.49 | Polyketide | erdacin | uncultured soil bacterium V167

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00011_NZ_ATVI.. - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 202,460 - 225,657 nt. (total: 23,198 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000630.1 |  | 0.25 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000640.1 |  | 0.24 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000635.1 |  | 0.22 | Terpene | carotenoid | Paracoccus sp. N81106
BGC0000642.1 |  | 0.22 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0000639.1 |  | 0.22 | Terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000638.1 |  | 0.21 | Terpene | carotenoid | Pantoea ananatis
BGC0000641.1 |  | 0.21 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000636.1 |  | 0.21 | Terpene | carotenoid | Brevibacterium linens
BGC0000643.1 |  | 0.21 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000386.1 |  | 0.20 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000630.1 |  | 0.58 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000640.1 |  | 0.57 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000635.1 |  | 0.55 | Terpene | carotenoid | Paracoccus sp. N81106
BGC0000642.1 |  | 0.55 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0000639.1 |  | 0.55 | Terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000638.1 |  | 0.54 | Terpene | carotenoid | Pantoea ananatis
BGC0000641.1 |  | 0.54 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000636.1 |  | 0.53 | Terpene | carotenoid | Brevibacterium linens
BGC0000643.1 |  | 0.53 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000386.1 |  | 0.52 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names