LOCUS       NC_017168.1            26788 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_017168.1 Yersinia pestis A1122, complete sequence.
ACCESSION   NC_017168
VERSION     NC_017168.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:54:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 510292
            Orig. end    :: 537080
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..26788
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[520292:527080]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16788
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..26788
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..26788
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="3"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(1735..2052)
                     /locus_tag="ctg1_443"
                     /transl_table=11
                     /translation="VIGNERHGLVGVIGADLIRNAKIPLILLVAVLISAVLVVTTAHRT
                     RLLTAEREQLVLERDALDIEWRNLILEENALGDHSRVESIAIEKLKMQHVDPSQENIVI
                     K"
     PFAM_domain     complement(1741..2022)
                     /aSDomain="FtsL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04999.15"
                     /description="Cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_443_0071"
                     /evalue="8.30E-35"
                     /label="ctg1_443"
                     /locus_tag="ctg1_443"
                     /protein_end="104"
                     /protein_start="10"
                     /score="118.7"
                     /tool="antismash"
                     /translation="GVIGADLIRNAKIPLILLVAVLISAVLVVTTAHRTRLLTAEREQL
                     VLERDALDIEWRNLILEENALGDHSRVESIAIEKLKMQHVDPSQENIVI"
     aSDomain        complement(1744..1989)
                     /aSDomain="TIGR02209"
                     /aSTool="tigrfam"
                     /description="ftsL_broad: cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_443_0019"
                     /evalue="7.20E-28"
                     /identifier="TIGR02209"
                     /label="ctg1_443"
                     /locus_tag="ctg1_443"
                     /protein_end="103"
                     /protein_start="21"
                     /score="94.3"
                     /tool="antismash"
                     /translation="KIPLILLVAVLISAVLVVTTAHRTRLLTAEREQLVLERDALDIEW
                     RNLILEENALGDHSRVESIAIEKLKMQHVDPSQENIV"
     CDS             complement(2049..3011)
                     /locus_tag="ctg1_444"
                     /transl_table=11
                     /translation="MVDNNKTVDNNYKHTSVLLDEAVKGLNIRDNGIYIDGTFGRGGHS
                     RLILSQLGPEGRLIAIDRDPEAIEAAKQITDPRFSIVHGPFSDLAHYVRDLDLVGRIDG
                     ILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFG
                     EERFAKRLAKAIVERNLTQPMTRTKELADLIANASPFRDKHKHPATRSFQAIRIYINSE
                     LEEIERALDGAHEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLR
                     SMGGRTLKSVGKMMPGDAEIAENPRARSSVLRFAERIGE"
     PFAM_domain     complement(2061..2978)
                     /aSDomain="Methyltransf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01795.21"
                     /description="MraW methylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_444_0072"
                     /evalue="2.20E-116"
                     /label="ctg1_444"
                     /locus_tag="ctg1_444"
                     /protein_end="317"
                     /protein_start="11"
                     /score="388.8"
                     /tool="antismash"
                     /translation="YKHTSVLLDEAVKGLNIRDNGIYIDGTFGRGGHSRLILSQLGPEG
                     RLIAIDRDPEAIEAAKQITDPRFSIVHGPFSDLAHYVRDLDLVGRIDGILLDLGVSSPQ
                     LDDAERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLAKA
                     IVERNLTQPMTRTKELADLIANASPFRDKHKHPATRSFQAIRIYINSELEEIERALDGA
                     HEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKSVG
                     KMMPGDAEIAENPRARSSVLRFAER"
     aSDomain        complement(2061..2984)
                     /aSDomain="TIGR00006"
                     /aSTool="tigrfam"
                     /description="TIGR00006: 16S rRNA
                     (cytosine(1402)-N(4))-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_444_0020"
                     /evalue="5.10E-126"
                     /identifier="TIGR00006"
                     /label="ctg1_444"
                     /locus_tag="ctg1_444"
                     /protein_end="317"
                     /protein_start="9"
                     /score="418.2"
                     /tool="antismash"
                     /translation="NNYKHTSVLLDEAVKGLNIRDNGIYIDGTFGRGGHSRLILSQLGP
                     EGRLIAIDRDPEAIEAAKQITDPRFSIVHGPFSDLAHYVRDLDLVGRIDGILLDLGVSS
                     PQLDDAERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLA
                     KAIVERNLTQPMTRTKELADLIANASPFRDKHKHPATRSFQAIRIYINSELEEIERALD
                     GAHEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKS
                     VGKMMPGDAEIAENPRARSSVLRFAER"
     CDS             complement(3014..3472)
                     /locus_tag="ctg1_445"
                     /transl_table=11
                     /translation="MFRGATMVNLDSKGRLAVPTRYRESLNEESQGQMVCTIDLHQPCL
                     LLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGL
                     NKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQGLSL"
     aSDomain        complement(3020..3472)
                     /aSDomain="TIGR00242"
                     /aSTool="tigrfam"
                     /description="TIGR00242: division/cell wall cluster
                     transcriptional repressor MraZ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_445_0021"
                     /evalue="1.30E-63"
                     /identifier="TIGR00242"
                     /label="ctg1_445"
                     /locus_tag="ctg1_445"
                     /protein_end="151"
                     /protein_start="0"
                     /score="211.2"
                     /tool="antismash"
                     /translation="MFRGATMVNLDSKGRLAVPTRYRESLNEESQGQMVCTIDLHQPCL
                     LLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGL
                     NKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQGLS"
     PFAM_domain     complement(3053..3244)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_445_0074"
                     /evalue="2.50E-20"
                     /label="ctg1_445"
                     /locus_tag="ctg1_445"
                     /protein_end="140"
                     /protein_start="76"
                     /score="72.3"
                     /tool="antismash"
                     /translation="LLGHASECQMDGAGRLLIAGTLRQHAGLNKEVMLVGQFNKFELWD
                     EQTWYQQVKDDIDAEQSTQ"
     PFAM_domain     complement(3248..3472)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_445_0073"
                     /evalue="1.60E-24"
                     /label="ctg1_445"
                     /locus_tag="ctg1_445"
                     /protein_end="75"
                     /protein_start="0"
                     /score="85.7"
                     /tool="antismash"
                     /translation="MFRGATMVNLDSKGRLAVPTRYRESLNEESQGQMVCTIDLHQPCL
                     LLYPLPEWEIIEQKLSRLSSMNPAERRVQR"
     CDS             4574..5014
                     /locus_tag="ctg1_446"
                     /transl_table=11
                     /translation="MFSTGPRWRSAVADTFALVVYCFVIGMAIEVVISGMTFRQSLSSR
                     LLSIPVNILIAWPYGMYRDAFIRFAQRHAGQRFWARNLADLLAYVSFQSPVYAMILWSV
                     GADFEQMISAVASNAVVSMVMGVAYGYFLEYCRRLFRVAGYV"
     PFAM_domain     4589..4999
                     /aSDomain="AlaE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06610.15"
                     /description="L-alanine exporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_446_0075"
                     /evalue="3.50E-73"
                     /label="ctg1_446"
                     /locus_tag="ctg1_446"
                     /protein_end="142"
                     /protein_start="5"
                     /score="244.4"
                     /tool="antismash"
                     /translation="PRWRSAVADTFALVVYCFVIGMAIEVVISGMTFRQSLSSRLLSIP
                     VNILIAWPYGMYRDAFIRFAQRHAGQRFWARNLADLLAYVSFQSPVYAMILWSVGADFE
                     QMISAVASNAVVSMVMGVAYGYFLEYCRRLFRV"
     CDS             complement(5145..6155)
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 207.6; E-value: 4.7e-63)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_447"
                     /transl_table=11
                     /translation="VKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREH
                     NYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPD
                     NEMRCVEHLLQRQVDAIIVSTALPPEHPFYQRWAKDPFPIIALDRALDREHFISVVGAD
                     QEDAQMLAQELRSFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVEYLYANSYER
                     EAAGVLFAEWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPCNLAIATFGDNELLDF
                     LECPVLAVAQRHRDVAERVLELVLASLDEPHKPKPGLTRIRRNLFRRGTLSLSRR"
     aSDomain        complement(5172..6152)
                     /aSDomain="TIGR02417"
                     /aSTool="tigrfam"
                     /description="fruct_sucro_rep: D-fructose-responsive
                     transcription factor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_447_0022"
                     /evalue="1.00E-148"
                     /identifier="TIGR02417"
                     /label="ctg1_447"
                     /locus_tag="ctg1_447"
                     /protein_end="328"
                     /protein_start="1"
                     /score="492.9"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREHN
                     YHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDN
                     EMRCVEHLLQRQVDAIIVSTALPPEHPFYQRWAKDPFPIIALDRALDREHFISVVGADQ
                     EDAQMLAQELRSFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVEYLYANSYERE
                     AAGVLFAEWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPCNLAIATFGDNELLDFL
                     ECPVLAVAQRHRDVAERVLELVLASLDEPHKPKPGLTRIRRNLFRR"
     PFAM_domain     complement(5244..5972)
                     /aSDomain="Peripla_BP_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00532.23"
                     /description="Periplasmic binding proteins and sugar
                     binding domain of LacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_447_0077"
                     /evalue="6.20E-14"
                     /label="ctg1_447"
                     /locus_tag="ctg1_447"
                     /protein_end="304"
                     /protein_start="61"
                     /score="52.2"
                     /tool="antismash"
                     /translation="RSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNE
                     MRCVEHLLQRQVDAIIVSTALPPEHPFYQRWAKDPFPIIALDRALDREHFISVVGADQE
                     DAQMLAQELRSFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVEYLYANSYEREA
                     AGVLFAEWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPCNLAIATFGDNELLDFLE
                     CPVLAVAQRHRDVAERVLELV"
     PFAM_domain     complement(6006..6152)
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00356.23"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_447_0076"
                     /evalue="1.50E-18"
                     /label="ctg1_447"
                     /locus_tag="ctg1_447"
                     /protein_end="50"
                     /protein_start="1"
                     /score="66.4"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREHN
                     YHPN"
     CDS             complement(6660..7118)
                     /locus_tag="ctg1_448"
                     /transl_table=11
                     /translation="MRDEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLC
                     EWKNVNILEAEYCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNRE
                     FWCRGYYVDTVGKNTARIQEYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
     PFAM_domain     complement(6732..7085)
                     /aSDomain="Y1_Tnp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01797.18"
                     /description="Transposase IS200 like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_448_0078"
                     /evalue="4.40E-36"
                     /label="ctg1_448"
                     /locus_tag="ctg1_448"
                     /protein_end="129"
                     /protein_start="11"
                     /score="123.8"
                     /tool="antismash"
                     /translation="WNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLCEWKNVNILEAE
                     YCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTV
                     GKNTARIQEYIKHQ"
     CDS             complement(7317..7811)
                     /locus_tag="ctg1_449"
                     /transl_table=11
                     /translation="MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKR
                     CAEIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGDKIM
                     R"
     aSDomain        complement(7332..7805)
                     /aSDomain="TIGR00119"
                     /aSTool="tigrfam"
                     /description="acolac_sm: acetolactate synthase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_449_0023"
                     /evalue="6.40E-66"
                     /identifier="TIGR00119"
                     /label="ctg1_449"
                     /locus_tag="ctg1_449"
                     /protein_end="160"
                     /protein_start="2"
                     /score="219.1"
                     /tool="antismash"
                     /translation="RRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRM
                     TIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCA
                     EIFRGQIVDVTATLYTVQLAGTSEKLDAFLNAVREVAEIVEVARSGIVGVSRGD"
     PFAM_domain     complement(7335..7559)
                     /aSDomain="ALS_ss_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10369.11"
                     /description="Small subunit of acetolactate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_449_0080"
                     /evalue="1.90E-23"
                     /label="ctg1_449"
                     /locus_tag="ctg1_449"
                     /protein_end="159"
                     /protein_start="84"
                     /score="82.5"
                     /tool="antismash"
                     /translation="REIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTS
                     EKLDAFLNAVREVAEIVEVARSGIVGVSRG"
     PFAM_domain     complement(7605..7799)
                     /aSDomain="ACT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01842.27"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_449_0079"
                     /evalue="8.20E-15"
                     /label="ctg1_449"
                     /locus_tag="ctg1_449"
                     /protein_end="69"
                     /protein_start="4"
                     /score="54.4"
                     /tool="antismash"
                     /translation="ILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTI
                     QTVGDAKVLEQIEKQLHKLV"
     CDS             complement(7814..9541)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 583.2;
                     E-value: 9.1e-177)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_450"
                     /transl_table=11
                     /translation="MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDH
                     VLVRHEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVP
                     SSLIGFDAFQECDMVGISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPK
                     DIVGPAVKMPYAYPEQVSLRSYNPTVQGHRGQIKRALQTIMAAKRPIMYVGGGAINAAC
                     HEELLILAEKLNLPVTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGV
                     RFDDRTTNNLAKYCPDATVLHIDIDPTSISKTVTADIPIVGDAKQVLTQMLDLLSQVGC
                     TQDFDSLRDWWQSIEQWRTRNCLGYNKDSGKIKPQAVIEALHRLTKGDAYVTSDVGQHQ
                     MFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKLALPNETVVCVTGDGSIQMNIQEL
                     STALQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVA
                     INTPDELESKLADALTQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWLSKTERT"
     aSDomain        complement(7832..9532)
                     /aSDomain="TIGR00118"
                     /aSTool="tigrfam"
                     /description="acolac_lg: acetolactate synthase, large
                     subunit, biosynthetic type"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_450_0024"
                     /evalue="9.00E-278"
                     /identifier="TIGR00118"
                     /label="ctg1_450"
                     /locus_tag="ctg1_450"
                     /protein_end="570"
                     /protein_start="3"
                     /score="920.2"
                     /tool="antismash"
                     /translation="LSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLV
                     RHEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSL
                     IGFDAFQECDMVGISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPKDIV
                     GPAVKMPYAYPEQVSLRSYNPTVQGHRGQIKRALQTIMAAKRPIMYVGGGAINAACHEE
                     LLILAEKLNLPVTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFD
                     DRTTNNLAKYCPDATVLHIDIDPTSISKTVTADIPIVGDAKQVLTQMLDLLSQVGCTQD
                     FDSLRDWWQSIEQWRTRNCLGYNKDSGKIKPQAVIEALHRLTKGDAYVTSDVGQHQMFA
                     ALYYPFDKPRRWINSGGLGTMGFGLPAALGVKLALPNETVVCVTGDGSIQMNIQELSTA
                     LQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVAINT
                     PDELESKLADALTQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWLS"
     PFAM_domain     complement(7904..8362)
                     /aSDomain="TPP_enzyme_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02775.23"
                     /description="Thiamine pyrophosphate enzyme, C-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_450_0083"
                     /evalue="2.00E-49"
                     /label="ctg1_450"
                     /locus_tag="ctg1_450"
                     /protein_end="546"
                     /protein_start="393"
                     /score="167.4"
                     /tool="antismash"
                     /translation="DVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKLALP
                     NETVVCVTGDGSIQMNIQELSTALQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSY
                     MDSLPDFVKLAEAYGHIGVAINTPDELESKLADALTQLSETNRLVFVDV"
     PFAM_domain     complement(8552..8956)
                     /aSDomain="TPP_enzyme_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00205.24"
                     /description="Thiamine pyrophosphate enzyme, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_450_0082"
                     /evalue="8.00E-47"
                     /label="ctg1_450"
                     /locus_tag="ctg1_450"
                     /protein_end="330"
                     /protein_start="195"
                     /score="158.5"
                     /tool="antismash"
                     /translation="IKRALQTIMAAKRPIMYVGGGAINAACHEELLILAEKLNLPVTSS
                     LMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDRTTNNLAKYCPDAT
                     VLHIDIDPTSISKTVTADIPIVGDAKQVLTQ"
     PFAM_domain     complement(9032..9529)
                     /aSDomain="TPP_enzyme_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02776.20"
                     /description="Thiamine pyrophosphate enzyme, N-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_450_0081"
                     /evalue="6.30E-58"
                     /label="ctg1_450"
                     /locus_tag="ctg1_450"
                     /protein_end="170"
                     /protein_start="4"
                     /score="195.3"
                     /tool="antismash"
                     /translation="SGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVR
                     HEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLI
                     GFDAFQECDMVGISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPKDIVG
                     PAV"
     CDS             complement(10001..11806)
                     /NRPS_PKS="Domain: AMP-binding (14-470). E-value: 1.7e-86.
                     Score: 282.2. Matches aSDomain:
                     nrpspksdomains_ctg1_451_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     268.4; E-value: 1.6e-81)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_451"
                     /sec_met_domain="AMP-binding (E-value: 3.2e-89, bitscore:
                     297.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKLHQYHLVRRLRQQVSDRSELVAFREWSPEGEKQLNWQQIDE
                     HVTRISTALLSLGAAIQERIGIFANNSMAWSLVDLAILQLRGVSVPLYATNTAAQAAYI
                     VNDADVRILFVGEQSQFDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQQQQ
                     PDTVQQHLLTTRIEGCDLDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTP
                     QDVSLSFLPLSHVFERAWSFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEK
                     VFSAINDKVALAKWHQRVLFHWAVGCGERKFKRLQQGRPLPWLSEQMYTLADRLVLRKL
                     RGVLGGRVRFLPAAGARLDDNIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSI
                     GKPLPGIDVRLGAENEIQVRGPIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHL
                     FITERLKDLMKTSGGKYIAPQMIEGTLGQDRFIEQVAIIADTRKFVSALIVPSFESLEE
                     YARSINLKYHDRLELLRHSHIVNMFEQRLKEIQKELALFEQVKKFTLLPQAFTMETGEL
                     TPTMKLRRKIILQRYQNEIDLMYSD"
     aSDomain        complement(10397..11764)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_451_AMP-binding.1"
                     /evalue="1.70E-86"
                     /label="ctg1_451_AMP-binding.1"
                     /locus_tag="ctg1_451"
                     /protein_end="470"
                     /protein_start="14"
                     /score="282.2"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RQQVSDRSELVAFREWSPEGEKQLNWQQIDEHVTRISTALLSLGA
                     AIQERIGIFANNSMAWSLVDLAILQLRGVSVPLYATNTAAQAAYIVNDADVRILFVGEQ
                     SQFDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQQQQPDTVQQHLLTTRIE
                     GCDLDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTPQDVSLSFLPLSHVF
                     ERAWSFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKW
                     HQRVLFHWAVGCGERKFKRLQQGRPLPWLSEQMYTLADRLVLRKLRGVLGGRVRFLPAA
                     GARLDDNIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSIGKPLPGIDVRLGAE
                     NEIQVRGPIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHLFITERLKDLMKT"
     PFAM_domain     complement(10397..11764)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_451_0084"
                     /evalue="3.30E-90"
                     /label="ctg1_451"
                     /locus_tag="ctg1_451"
                     /protein_end="470"
                     /protein_start="14"
                     /score="302.8"
                     /tool="antismash"
                     /translation="RQQVSDRSELVAFREWSPEGEKQLNWQQIDEHVTRISTALLSLGA
                     AIQERIGIFANNSMAWSLVDLAILQLRGVSVPLYATNTAAQAAYIVNDADVRILFVGEQ
                     SQFDIAITLQPLCPQLAHIIVLDPAVDLRGCEYAQHLADFEQQQQPDTVQQHLLTTRIE
                     GCDLDDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTPQDVSLSFLPLSHVF
                     ERAWSFYVMHTGAQNVYIRNTDWVRSAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKW
                     HQRVLFHWAVGCGERKFKRLQQGRPLPWLSEQMYTLADRLVLRKLRGVLGGRVRFLPAA
                     GARLDDNIILFFQAIGVNIKYGYGMTETCATVSCWEEQNFRFGSIGKPLPGIDVRLGAE
                     NEIQVRGPIVMRGYFKKPQETLEAFTEDGWLKTGDAGALDAQGHLFITERLKDLMKT"
     CDS_motif       complement(10493..10564)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_451_0002"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_451"
                     /protein_end="438"
                     /protein_start="414"
                     /score="17.8"
                     /tool="antismash"
                     /translation="EIQVRGPIVMRGYFKKPQETLEAF"
     CDS_motif       complement(11201..11248)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_451_0001"
                     /evalue="9.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_451"
                     /protein_end="202"
                     /protein_start="186"
                     /score="24.3"
                     /tool="antismash"
                     /translation="LIYTSGTTGEPKGVML"
     CDS             complement(12343..13299)
                     /gene_functions="regulatory (smcogs) SMCOG1125:LysR family
                     transcriptional regulator (Score: 247.7; E-value: 2.7e-75)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_452"
                     /transl_table=11
                     /translation="MSEYNLVTDSQATKKESIDVHLRSVDLNLLTVFDAVMQMQNVTRA
                     AQSLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARARQLFGPVRQALQLVQNELP
                     GAGFEAKNSERLFNLSICSPLDVRLAAQIVQRVKQSAPNVQLVIKSYLNDNIEHQLRYQ
                     ETEFVIGYTEFDRPDFHRIPLFKDELVLAVSKDHPRINDSITENQLLSESHAVVSLDKK
                     GSFSEPYYDSTTSTQSIAYESTDMNSVLNIVSQTYFVAIAPRWLVKTYSEALNLKLISL
                     PWENTSRACYLTWHESTDRDKGHQWMKALLGQFSSPV"
     PFAM_domain     complement(12367..12936)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_452_0086"
                     /evalue="3.30E-20"
                     /label="ctg1_452"
                     /locus_tag="ctg1_452"
                     /protein_end="311"
                     /protein_start="121"
                     /score="72.5"
                     /tool="antismash"
                     /translation="CSPLDVRLAAQIVQRVKQSAPNVQLVIKSYLNDNIEHQLRYQETE
                     FVIGYTEFDRPDFHRIPLFKDELVLAVSKDHPRINDSITENQLLSESHAVVSLDKKGSF
                     SEPYYDSTTSTQSIAYESTDMNSVLNIVSQTYFVAIAPRWLVKTYSEALNLKLISLPWE
                     NTSRACYLTWHESTDRDKGHQWMKALL"
     PFAM_domain     complement(13045..13221)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_452_0085"
                     /evalue="1.00E-17"
                     /label="ctg1_452"
                     /locus_tag="ctg1_452"
                     /protein_end="85"
                     /protein_start="26"
                     /score="63.9"
                     /tool="antismash"
                     /translation="LNLLTVFDAVMQMQNVTRAAQSLGMSQPAVSNAVARLKVMFNDEL
                     FVRYGRGIQPTARA"
     CDS             13977..14192
                     /locus_tag="ctg1_453"
                     /transl_table=11
                     /translation="MDQFILYISTLPLSLSLTHKKIESNRQNNQHSCWVGRQAAAEKHG
                     KHNNPDNGNYAKQLKNHERLVQDNTL"
     CDS             14621..15079
                     /locus_tag="ctg1_454"
                     /transl_table=11
                     /translation="MRDEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLC
                     EWKNVNILEAECCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNRE
                     FWCRGYYVDTVGKNTARIQEYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
     PFAM_domain     14654..15007
                     /aSDomain="Y1_Tnp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01797.18"
                     /description="Transposase IS200 like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_454_0087"
                     /evalue="2.40E-36"
                     /label="ctg1_454"
                     /locus_tag="ctg1_454"
                     /protein_end="129"
                     /protein_start="11"
                     /score="124.6"
                     /tool="antismash"
                     /translation="WNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLCEWKNVNILEAE
                     CCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTV
                     GKNTARIQEYIKHQ"
     CDS             15226..16788
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 428.8;
                     E-value: 4.6e-130)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_455"
                     /sec_met_domain="HMGL-like (E-value: 3.5e-106, bitscore:
                     352.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEV
                     GFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATST
                     LHIESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGA
                     TTINIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGA
                     RQVEGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPI
                     PGNKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHR
                     MEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQ
                     SGSSVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGK
                     DALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVEKEKQRLQQNNQ
                     EMV"
     PFAM_domain     15235..16044
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_455_0088"
                     /evalue="2.60E-106"
                     /label="ctg1_455"
                     /locus_tag="ctg1_455"
                     /protein_end="273"
                     /protein_start="3"
                     /score="355.1"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFP
                     VSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHI
                     ESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTI
                     NIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLV"
     aSDomain        15235..16716
                     /aSDomain="TIGR00973"
                     /aSTool="tigrfam"
                     /description="leuA_bact: 2-isopropylmalate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_455_0025"
                     /evalue="7.00E-252"
                     /identifier="TIGR00973"
                     /label="ctg1_455"
                     /locus_tag="ctg1_455"
                     /protein_end="497"
                     /protein_start="3"
                     /score="834.1"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDIMEVGFP
                     VSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHI
                     ESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRVVEAAITAGATTI
                     NIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGLGERAGNCSLEEVIMAIKVRHEMLGVHTNINHQEIYRTSQLVSKICNMPIPGN
                     KAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPESIGLKEVQLNLTSRSGRAAVKHRMEE
                     MGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGS
                     SVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDAL
                     GQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLN"
     PFAM_domain     16330..16722
                     /aSDomain="LeuA_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08502.12"
                     /description="LeuA allosteric (dimerisation) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_455_0089"
                     /evalue="6.10E-37"
                     /label="ctg1_455"
                     /locus_tag="ctg1_455"
                     /protein_end="499"
                     /protein_start="368"
                     /score="126.6"
                     /tool="antismash"
                     /translation="QVFDYDLEALAFINKQQEEPEYYRLDYFSVQSGSSVMATASVKLV
                     CGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSAKGQGKDALGQVDIVVDHKG
                     RRFHGVGLATDIVESSAKALVHVLNNI"
     CDS             16791..17882
                     /locus_tag="ctg1_456"
                     /transl_table=11
                     /translation="MTKTYHIAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDV
                     GGAAIDRHGSPLPAATVAGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKL
                     FSNLRPARLYQGLEDFCPLRSDIAARGFDILCVRELTGGIYFGQPKGREGQGMHERAFD
                     TEVYHRFEIERIARIAFESARKRRSKVTSIDKANVLQSSILWREVVNGIAADYPDVALS
                     HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYE
                     PAGGSAPDIAGKNIANPIAQILSLTLLLRFSLGKDDAADAIERAINQALEQGYRTADLA
                     GDGHAIGTHEMGDIIAKFVVEGV"
     aSDomain        16806..17852
                     /aSDomain="TIGR00169"
                     /aSTool="tigrfam"
                     /description="leuB: 3-isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_456_0026"
                     /evalue="8.80E-166"
                     /identifier="TIGR00169"
                     /label="ctg1_456"
                     /locus_tag="ctg1_456"
                     /protein_end="354"
                     /protein_start="5"
                     /score="549.1"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGGAAI
                     DRHGSPLPAATVAGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLR
                     PARLYQGLEDFCPLRSDIAARGFDILCVRELTGGIYFGQPKGREGQGMHERAFDTEVYH
                     RFEIERIARIAFESARKRRSKVTSIDKANVLQSSILWREVVNGIAADYPDVALSHMYID
                     NATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSLTLLLRFSLGKDDAADAIERAINQALEQGYRTADLAGDGHA
                     IGTHEMGDI"
     PFAM_domain     16806..17855
                     /aSDomain="Iso_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00180.22"
                     /description="Isocitrate/isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_456_0090"
                     /evalue="4.20E-137"
                     /label="ctg1_456"
                     /locus_tag="ctg1_456"
                     /protein_end="355"
                     /protein_start="5"
                     /score="457.1"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEVMAQASKVLDAVRQRFGLKISTSVYDVGGAAI
                     DRHGSPLPAATVAGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLR
                     PARLYQGLEDFCPLRSDIAARGFDILCVRELTGGIYFGQPKGREGQGMHERAFDTEVYH
                     RFEIERIARIAFESARKRRSKVTSIDKANVLQSSILWREVVNGIAADYPDVALSHMYID
                     NATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSLTLLLRFSLGKDDAADAIERAINQALEQGYRTADLAGDGHA
                     IGTHEMGDII"
     CDS             17884..19314
                     /locus_tag="ctg1_457"
                     /transl_table=11
                     /translation="MGTTSSQSKTLYQKLYDAHIVHEAPNETPLLYIDRHLVHEVTSPQ
                     AFDGLRAMGRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLY
                     DLNHPFQGIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQT
                     LKQGRAKTMRIEVNGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGR
                     MTLCNMAIEMGAKAGLVAPDDTTFAYLKGRQFAPTGEQWEQGVAYWRTLKSDADAQFDT
                     IVTLDAADIAPQVTWGTNPGQVIAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKL
                     TEVAIDKVFIGSCTNSRIEDLRAAAAIAQGRKVAKGVQAIVVPGSGPVKAQAEAEGLDK
                     IFIAAGFEWRLPGCSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAA
                     AAVSGHFADVRELSATTH"
     aSDomain        17905..19296
                     /aSDomain="TIGR00170"
                     /aSTool="tigrfam"
                     /description="leuC: 3-isopropylmalate dehydratase, large
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_457_0027"
                     /evalue="1.60E-266"
                     /identifier="TIGR00170"
                     /label="ctg1_457"
                     /locus_tag="ctg1_457"
                     /protein_end="471"
                     /protein_start="7"
                     /score="882.2"
                     /tool="antismash"
                     /translation="SKTLYQKLYDAHIVHEAPNETPLLYIDRHLVHEVTSPQAFDGLRA
                     MGRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLYDLNHPFQ
                     GIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAK
                     TMRIEVNGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMA
                     IEMGAKAGLVAPDDTTFAYLKGRQFAPTGEQWEQGVAYWRTLKSDADAQFDTIVTLDAA
                     DIAPQVTWGTNPGQVIAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDK
                     VFIGSCTNSRIEDLRAAAAIAQGRKVAKGVQAIVVPGSGPVKAQAEAEGLDKIFIAAGF
                     EWRLPGCSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSGHF
                     ADVREL"
     PFAM_domain     17923..19272
                     /aSDomain="Aconitase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00330.22"
                     /description="Aconitase family (aconitate hydratase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_457_0091"
                     /evalue="1.20E-163"
                     /label="ctg1_457"
                     /locus_tag="ctg1_457"
                     /protein_end="463"
                     /protein_start="13"
                     /score="545.5"
                     /tool="antismash"
                     /translation="KLYDAHIVHEAPNETPLLYIDRHLVHEVTSPQAFDGLRAMGRPVR
                     QPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLYDLNHPFQGIVHVI
                     GPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMRIEV
                     NGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMAIEMGAK
                     AGLVAPDDTTFAYLKGRQFAPTGEQWEQGVAYWRTLKSDADAQFDTIVTLDAADIAPQV
                     TWGTNPGQVIAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDKVFIGSC
                     TNSRIEDLRAAAAIAQGRKVAKGVQAIVVPGSGPVKAQAEAEGLDKIFIAAGFEWRLPG
                     CSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSG"
     PFAM_domain     19329..19703
                     /aSDomain="Aconitase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00694.21"
                     /description="Aconitase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_458_0092"
                     /evalue="1.70E-39"
                     /label="ctg1_458"
                     /locus_tag="ctg1_458"
                     /protein_end="125"
                     /protein_start="0"
                     /score="135.3"
                     /tool="antismash"
                     /translation="MAKFIQHIGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFND
                     WRFLDDAGKVPNPDFVLNLPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPS
                     FADIFYGNAFNNQLLPVTLSE"
     aSDomain        19329..19892
                     /aSDomain="TIGR00171"
                     /aSTool="tigrfam"
                     /description="leuD: 3-isopropylmalate dehydratase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_458_0028"
                     /evalue="1.40E-97"
                     /identifier="TIGR00171"
                     /label="ctg1_458"
                     /locus_tag="ctg1_458"
                     /protein_end="188"
                     /protein_start="0"
                     /score="323.0"
                     /tool="antismash"
                     /translation="MAKFIQHIGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFND
                     WRFLDDAGKVPNPDFVLNLPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPS
                     FADIFYGNAFNNQLLPVTLSEADIDTLFQLVKENEGIEFVVDLEQQTVNAGGKSYAFEI
                     DPFRRHCMINGLDSIGLTLQHEHNI"
     CDS             19329..19931
                     /locus_tag="ctg1_458"
                     /transl_table=11
                     /translation="MAKFIQHIGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFND
                     WRFLDDAGKVPNPDFVLNLPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPS
                     FADIFYGNAFNNQLLPVTLSEADIDTLFQLVKENEGIEFVVDLEQQTVNAGGKSYAFEI
                     DPFRRHCMINGLDSIGLTLQHEHNISAYEKQQPEFLR"
     CDS             complement(20172..20441)
                     /locus_tag="ctg1_459"
                     /transl_table=11
                     /translation="LHRSLQLQIFNAIFIGIVAGIGMLYFQDLMPGRAGAATTLFTNSI
                     SSGVILAGVLQGVLTETWGHNAVYVAAMVLVILALIICAKVREA"
     CDS             20511..21533
                     /gene_functions="other (smcogs) SMCOG1213:transposase
                     (Score: 401; E-value: 7.4e-122)"
                     /gene_kind="other"
                     /locus_tag="ctg1_460"
                     /transl_table=11
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEPP
                     KYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIRSL
                     SVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMRYDT
                     LETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRLC
                     RPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVANQRKH
                     ETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDSFCRGVA
                     "
     PFAM_domain     20535..20630
                     /aSDomain="HTH_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02796.17"
                     /description="Helix-turn-helix domain of resolvase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_460_0093"
                     /evalue="1.30E-08"
                     /label="ctg1_460"
                     /locus_tag="ctg1_460"
                     /protein_end="40"
                     /protein_start="8"
                     /score="34.9"
                     /tool="antismash"
                     /translation="EIKILHKQGMSSRAIARELGISRNTVKRYLQA"
     PFAM_domain     20862..21188
                     /aSDomain="rve"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00665.28"
                     /description="Integrase core domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_460_0094"
                     /evalue="8.60E-21"
                     /label="ctg1_460"
                     /locus_tag="ctg1_460"
                     /protein_end="226"
                     /protein_start="117"
                     /score="74.2"
                     /tool="antismash"
                     /translation="TEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMRYD
                     TLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRL
                     CRPFR"
     CDS             21533..22312
                     /gene_functions="other (smcogs) SMCOG1151:transposase
                     (Score: 308.8; E-value: 3e-94)"
                     /gene_kind="other"
                     /locus_tag="ctg1_461"
                     /transl_table=11
                     /translation="MMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLEH
                     LLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNEN
                     IVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGVM
                     APRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTS
                     AMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE"
     PFAM_domain     21566..22282
                     /aSDomain="IstB_IS21"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01695.19"
                     /description="IstB-like ATP binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_461_0095"
                     /evalue="2.30E-112"
                     /label="ctg1_461"
                     /locus_tag="ctg1_461"
                     /protein_end="250"
                     /protein_start="11"
                     /score="374.4"
                     /tool="antismash"
                     /translation="LAGQLQLESLISAAPALSQQAVDQEWSYMDFLEHLLHEEKLARHQ
                     RKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNENIVLLGPSGVGK
                     THLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGVMAPRLLIIDEIG
                     YLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTSAMLDRILHHSH
                     VVQIKGESYRLRQKRKA"
     CDS             complement(22356..23312)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 75.8; E-value: 4.1e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_462"
                     /transl_table=11
                     /translation="MRSARAFSRRINPVFLAFFVVAFLSGIAGALQAPTLSLFLSTELK
                     VRPLWVGLFYTVNAIAGITVSFLLAKRSDLGGDRRKLILICYLMAVGNCLLFAFNRDYL
                     TLITLGVLMASVANTAMPQIFALAREYADNSAREVVMFSSIMRAQLSLAWVIGPPLSFM
                     LALNYGFTLMFSIAAGIFVISALVVWFILPSVKQPEPVADAPVVVQGSLFADKNVLLLF
                     IASMLMWTCNTMYIIDMPLYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGK
                     RKIMLFAVMAGVLFYTGLVLFKFKTALMILLSTTDEK"
     PFAM_domain     complement(22383..23258)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_462_0096"
                     /evalue="2.60E-29"
                     /label="ctg1_462"
                     /locus_tag="ctg1_462"
                     /protein_end="310"
                     /protein_start="18"
                     /score="102.3"
                     /tool="antismash"
                     /translation="FVVAFLSGIAGALQAPTLSLFLSTELKVRPLWVGLFYTVNAIAGI
                     TVSFLLAKRSDLGGDRRKLILICYLMAVGNCLLFAFNRDYLTLITLGVLMASVANTAMP
                     QIFALAREYADNSAREVVMFSSIMRAQLSLAWVIGPPLSFMLALNYGFTLMFSIAAGIF
                     VISALVVWFILPSVKQPEPVADAPVVVQGSLFADKNVLLLFIASMLMWTCNTMYIIDMP
                     LYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGKRKIMLFAVMAGVLFYTGL
                     VLFKFKTALMI"
     CDS             23976..25637
                     /gene_functions="transport (smcogs) SMCOG1068:extracellular
                     solute-binding protein family 5 (Score: 70.2; E-value:
                     2.9e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_463"
                     /transl_table=11
                     /translation="MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLG
                     KMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVR
                     QMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEENGE
                     LEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRS
                     PTPYVIDVYLHSPDHWLPWLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQL
                     KIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQADDTGKNELESRLEEGCYFLL
                     FDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPK
                     PEGLNELTLTFYSEHSEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGS
                     ANFYLPLEFSLFATLYEMPLLQHCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPL
                     FHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA"
     PFAM_domain     23988..24329
                     /aSDomain="SgrR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12793.9"
                     /description="Sugar transport-related sRNA regulator
                     N-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_463_0097"
                     /evalue="1.10E-41"
                     /label="ctg1_463"
                     /locus_tag="ctg1_463"
                     /protein_end="118"
                     /protein_start="4"
                     /score="141.8"
                     /tool="antismash"
                     /translation="RLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQH
                     AGWLDWQAEAGRGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVRQMLL
                     SQLGRSFRQG"
     PFAM_domain     24465..24893
                     /aSDomain="SBP_bac_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00496.24"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 5 Middle"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_463_0098"
                     /evalue="1.30E-17"
                     /label="ctg1_463"
                     /locus_tag="ctg1_463"
                     /protein_end="306"
                     /protein_start="163"
                     /score="64.0"
                     /tool="antismash"
                     /translation="LEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRL
                     IPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLPWLLGSVHAMILPQEWETQPDFHRQPIG
                     TGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPE"
     CDS             complement(25738..26022)
                     /locus_tag="ctg1_464"
                     /transl_table=11
                     /translation="MAWLYISLSVVSLFFYYYVVSHLLYSKNIYLNISSLAFTCLFSIF
                     HYSAFISDRIPLFGINTEDNDFLHYITLLFSYSYAIPFIIAYKKLYNKK"
ORIGIN
        1 aaacgccgcc catgatggca ccgaataccg gtgcagaaac cgcaccaccg taatatttcc
       61 ctgcctgcgg gtcattgatc accacaacca gagcaaatcg agggttactc gcgggcgcaa
      121 cgccagcggt gtaagcgagg tatcgatcca tatacttgcc atcgggaccg acttttttgg
      181 ccgtaccggt tttaatcgcg atacggtagc ctttgatcgc cgctttggta ccaccaccgc
      241 caggcagtgc cacgctttcc atcatatgaa ccacggtgcg taccaggggt tcagggaaga
      301 tgcgttcacc ggcgacaggt gggtcaactc gggttatcga cagcgggcga tagaccccca
      361 tgctgccgat ggttgcatag actcgcgcta gttgtaacgg tgttaccatt agcccgtagc
      421 cgaaagagaa ggtggccctc tctatgtcag accaccgttg ttttttagga tataagccac
      481 tgctttctcc gaccaacccc aaattggtcg ctttcccaaa cccaaaccgt gagtaagtat
      541 ctactaacgc tgaggatggc atcgctaacg ccagtttaga aacaccgacg ttactcgact
      601 tctgtaagat cccagtgacg gatagctcag cgtaacgggc cacgtcttta atctggtgac
      661 cgttaacaaa gtacggcaag gtattcagca cactgttctc tttcacaaca ccatgctgta
      721 aggccgtcat cactaccatt ggcttgactg tcgagccggg ttcaaaaata tcggttattg
      781 cccggttacg catcgcgtct ttcggcgtac cggttaggtt attcgggttg taagacgggc
      841 tgttcgccat cgccaagact tcaccggtgt tcacatcgac taataccgcc gtgcccgatt
      901 ctgctttgtt aaacgccacc gcattattga gctcgcggta caccaacgcc tgcaaacgct
      961 cgtccacact cagcaccagg ttatgcgccg cctggctgtc aacagaggag atatcttcaa
     1021 taacacggcc ataatggtct ttgcgcaccg ttcgctcgcc cggttggccg gtgagccagc
     1081 gatcaaaact tttctcaaca ccttcaatcc cttgcccatc gatattggtc acaccaataa
     1141 tgtgagccat cacctgacct gccggatagt agcgacggga ttcctgacgt agatggatac
     1201 cgggtaattt cagcttgcgg atgtagtcgc caatcgcggg gttcacctga cgggccagat
     1261 agacaaagcg gccttttgga ttggcattaa tgcgcgtggc aagttgatct aaagggattt
     1321 ctaatgcatc cgacagggct ttccagcggg tatccagaga gatccccccc tgttcaatca
     1381 gttcttttgg atcggcccaa accgcattga cgggtacact gaccgccaaa gggcggccag
     1441 agcgatcgct tatcatgcca cgcgccgtcg gcacctcttg tactcgcagc gagcgcatat
     1501 ccccctcgcg caccagctta tcggggttga tcacttgcag gtatgcggta cgcataatca
     1561 gcccaaccaa tgccagtaaa atacaaccgc acagcaacgc aaaacgccag ctaataaagc
     1621 tggcttgttc ttcctgacgc tttaacttcc cggggcgcgc tgtcttcatg tattaccttg
     1681 gcgactgcga gtcatgatgg tcactgattc ctgtactggt taaaaaacaa cctattattt
     1741 aatcacaatg ttttcttgtg atggatcgac atgctgcatt ttcagttttt caatagcgat
     1801 actttcaacg cggctgtgat cgcctaatgc attctcttct aaaattaggt tgcgccactc
     1861 aatatccagc gcatcccttt ctaataccaa ctgctcacgc tcggcggtca gtaagcgagt
     1921 acgatgcgcc gtggtcacga cgagcacggc agagatcaac accgcgacca gtaggattaa
     1981 tgggattttg gcattgcgga taagatctgc cccaatgacc ccgactaaac catgacgctc
     2041 gttgcctatc actcaccgat cctctcagca aaacggagta ccgagctgcg agcgcgtggg
     2101 ttttcagcaa tttctgcatc ccctggcatc attttgccaa ccgatttcag tgtgcgccct
     2161 cccatgctgc gcagttgtgc ctccgtcaat ggcaagcctg cggggacctg tggcccacgg
     2221 ctatgatgac gaataaagtt tttcacaata cgatcttcaa gggagtggaa gctgatcact
     2281 gacaaacggc cttcaggcgc caaaacctcg tgcgcgccat cgagtgcacg ttcgatctct
     2341 tccaattcac tgttaatgta aatacggata gcctggaagc tgcgagtggc tggatgctta
     2401 tgcttatccc taaacggact ggcattagcg atcaggtcag ccagctcttt ggtccgtgtc
     2461 atgggctgag tgaggttacg ctcaacaatc gccttggcca aacgcttggc aaagcgctct
     2521 tcgccgaagg ttttcagcac ccaggcaatg tcatcagcgc tggctttcat cagccattca
     2581 gcagcagaca ggccacgaga agggtccatc cgcatatcca gcggcccatc acgcataaaa
     2641 gagaagccgc gttcagcatc atcaagttgt ggtgatgaaa cgcccaaatc cagcaatatg
     2701 ccgtcaatac ggccaacgag atccagatcc cgcacataat gtgctaaatc agaaaaagga
     2761 ccatgtacga tagagaaacg ggggtcggtg atctgtttcg ccgcttcgat agcttctgga
     2821 tcccgatcaa ttgcaattaa gcgcccttct ggcccaagtt gggacaaaat caaacgcgaa
     2881 tggccgccgc ggccaaaagt gccgtcaatg tagataccgt tatcacggat attcaggccc
     2941 tttacggcct catccagcaa tacactggta tgtttgtagt tgttatctac cgttttgttg
     3001 ttgtctacca tacttatagc gataagccct gtagccgctc agacaaaggt tcctgagttg
     3061 actgttctgc gtcgatgtca tccttgactt gttgatacca ggtctgttca tcccacagct
     3121 caaatttatt gaactgccca accagcatca cttctttgtt tagcccggcg tgctgacgca
     3181 atgtccctgc aatcagtaag cgcccagcgc cgtccatctg acattcactg gcatgcccta
     3241 acagcaaacg ctgaactcga cgttcagcag ggttcatgct cgacagacgc gataactttt
     3301 gttcaatgat ttcccattca ggcagtgggt aaagcaacag gcatggttgg tgaaggtcta
     3361 tggtacagac catctggcct tgcgattcct cattcagtga ctcccgataa cgggtaggta
     3421 cggcaagccg ccctttactg tcgaggttaa ccattgttgc accacgaaac atgactgagt
     3481 taccccttca cgacccaatt caccactttc ccccacaaat ccccacattt aagagtttac
     3541 ggatggtatg aaaaccttgt caagccagag ccgatgcggt ttaacaatat ttatgggttg
     3601 tttttgcgat atatcccata gaaggggata ttttaaggga tgaaatagaa aataacgtca
     3661 tgataaacgg gctatttttc cgccagtaat tctggctact taaataaata ataaattgtc
     3721 aattaattgt ctcattattt ccttctgcaa ggaaggtctc actttcagta tgaaaattac
     3781 actattcgaa atggagcaaa ctgagtgcaa atcctgtgac tactggtctt ccctaaagcg
     3841 cgctagcagt aaatgaggct caaaaccacg ctgacacaat aatacccttg cagataacca
     3901 gcattacagc ggcgtcattt tacttcaatt agctgacgag agatttatct attttgaaat
     3961 aaattattag tgcgtatttt ttgtcacgat tgaaatatga atctcttcgg acagataact
     4021 cttaaattaa aaaaacgggt taaatatgag gttattgaca aagtgcccgc gacggagaga
     4081 acaggcagat cgtaaagacg ccgtaaatac atccatgtag gctcgagccg cgccatcctt
     4141 ggcgcggacg ctttactcct ctgcctatcc tcaccgttca agatcgagtc atcggggttt
     4201 gtcagcagtc tggttaaata tgtgtgtttt ttatcttctt ctgtttgcag tttggcttaa
     4261 acggcagaaa ataccggcgt ttttcacaga aacaacaacc aactgttttt taaaggaaat
     4321 cctattaatt tttgttttaa tcaccaaaaa aaggacattt ccccacagga taaagtataa
     4381 aaatcagtca aatgttaaaa ataaaaattt tatgctggtt atattaacca attcagtaat
     4441 gtaaactacc aacaaaacaa aataacgaca caataaccct atatttaaat aataatcaaa
     4501 atataaaacc aactaatgat tttgataaaa agctttttgg cagatttatc tcccaagcat
     4561 ggagtttatg acaatgtttt caactgggcc tcgttggcgt agcgctgtag ccgatacctt
     4621 tgcactcgtc gtgtattgtt ttgtcatcgg catggcaatt gaagtggtta tctcgggaat
     4681 gaccttccgg caatcgcttt cttcgcgcct gctctcaata cccgtcaata ttcttattgc
     4741 ctggccttat ggtatgtatc gagatgcttt tatacgtttt gcccagcgcc atgctggcca
     4801 gcgtttttgg gcacgtaatt tggctgatct attagcttat gtcagtttcc agtcaccggt
     4861 ttatgccatg attttgtggt cggttggggc agatttcgag caaatgatat cagcggtcgc
     4921 cagtaacgcc gtggtttcaa tggttatggg ggtggcctac ggctattttt tggaatattg
     4981 tcgccggcta ttccgcgttg caggttatgt ttgatctacc tgttcgttat cttttatggc
     5041 gcggacactt ggctccccgg cctatcctca gcatcttcag atcgcgttat cggggtttgt
     5101 cagcaatcaa aatcagggcg ggtgccctga ttcgttatag tgaactacct gcggcttagg
     5161 cttagagtgc cacggcggaa taaattgcgg cgaatccgcg ttaaccccgg ttttggctta
     5221 tggggttcat ccagactggc caataccagc tccagcaccc gttcagcaac atcacgatgg
     5281 cgctgtgcca ctgccaatac tgggcattca aggaaatcta acagctcgtt atcaccaaaa
     5341 gtcgcaatgg ccagattgca gggtaagcgg ccactttgtt ttagggtgac gtccataaca
     5401 ccctgtaaaa gttggaatga cgtggtaaac agtgcctgtg gcattgggtg cgttttcagc
     5461 cattcagcaa acaacacacc tgcggcttcg cgttcatagc tgttggcata taggtattcc
     5521 actttacgcg gatcgtcctt ccacgcttca cgaaagccca tctcacgcag aaaactgact
     5581 gacagctccg gtagcgcccc cagataaagc accgattcag ccgggaagga gcgcagttct
     5641 tgcgctaaca tctgcgcatc ttcctgatcc gccccgacca cactgataaa atgctcacga
     5701 tcaagcgccc gatctaaggc aatgatcggg aatgggtctt tggcccagcg ctgatagaaa
     5761 gggtgttctg gcggcaatgc cgtcgacaca atgatcgcat caacctggcg ttgtaacagg
     5821 tgctcaacgc agcgcatttc attatccggc tggtcttctg aacaggctat cagcaactgg
     5881 taaccacgct gacgagcctg acgctccaga taattggcaa tacgggtgta gctggtattt
     5941 tccagatctg ggatcaccaa accgatcgag cgggttctgc ccgcgcgcaa acctgccgcg
     6001 actgcattcg ggtgatagtt atgttccctg acaaccgcca taactttatc tactgtttta
     6061 tcgctgaccc ggtactgttt cgctttgcca ttaatgacat aactggccgt tgtgcgcgaa
     6121 acgcccgcaa ggcgcgcgat ctcatccagt ttcacgttaa ccccttataa acccagtaaa
     6181 gtgatgaaaa gcagagcgct ctgccgagag ccagcatccc tgtgtctttt cagccgaact
     6241 tatcgaccca gaggatgata agtgaaccca aaaaatttgc ctacccagag ttatcagcgt
     6301 tgcagccaga cggcaagcga acgatcctga tgaactgatt tagatcaaat gatttgagtg
     6361 agcaagagcc gctagccaac aatttggcct ccagagcgat ctaacctcca aaataaggtg
     6421 atctccggat aaacaggcta tagacatagt ttaactatgg atataatccg ttatagatct
     6481 aaccgcagaa ctcactattg agcaaccgct ttaacggtta tataacgcta cttaggttaa
     6541 aaaataagaa aaataaatat cctccggcat agccggaggt ttttcatatg cgcctataag
     6601 gctctgttac cagccgcgcc ctaacaggcg catcgcgatc tgacatttgc atctatggat
     6661 tacttacggc ccgtaaacgg gctaccggga tacgggatcg agagttgctc acccatttta
     6721 tcctcttcca attggtgctt tatgtattct tgtatcctgg ccgtgttttt ccctaccgta
     6781 tcaacgtaat accctcgaca ccaaaactcc ctgttacggt atttgaactt caaatcgcca
     6841 aactgctcat aaagcatcag actgctcttt cccttcaggt accccataaa tcccgagaca
     6901 ctcatcttgg gcgggatctc cagaagcata tggatgtgat ccacacagta ttctgcttcc
     6961 aggatattca cgtttttcca ttcgcacagt tttcttaaaa tactgccaat cgctctgcgt
     7021 ttttccctgt agaacacctg ccttcggtac ttcggcgcaa aaactatatg atatttacag
     7081 ttccatcggg tgtgcgctaa gctcttttca tccctcattg ggaccccctt ttgatttctt
     7141 gttgaacatt tgcagttgcc agaccgcaaa ctgttttaac aaatcaaaag gggtttttat
     7201 aactgaccca aagctgaaag ctttactgaa cccccagcct agctgggggt tttctgggca
     7261 caaaaaagct caacgctatg cgctgagccc gatcattaga gcgaaatcag cattaattaa
     7321 cgcatgattt tgtcaccacg cgatacgccg acaatcccag agcgagcaac ttccactatt
     7381 tcagcgactt cacgcaccgc attcaaaaac gcatccagct tctcgctagt acccgctagc
     7441 tgaacggtat agagcgttgc ggtcacatcc acaatttgcc cacggaagat ttctgcacaa
     7501 cgcttcacct cttcacggcc ataaccactg gcttgcaact tcaccaacat gatttcgcgc
     7561 tcaacatgtg agccagaaac caactcactg acacgtaaga cgtccaccaa cttgtgcagc
     7621 tgcttttcaa tctgctccag aaccttggca tcacccacgg tctggatggt catgcgggaa
     7681 agcgttgggt catcggttgg cgcgaccgtc aggctttcga tattatagcc acgctgagaa
     7741 aacagcccca ccacccgtga gagtgcacct gactcatttt ccagcagtac tgataaaatc
     7801 cggcggcgca taattaagtc ctctccgttt tgcttagcca catttcgtcc atgccaccac
     7861 cacgaatctg catcgggtaa acatgttctg tttcatcgac agtcacatcc acaaagacca
     7921 aacgattggt ttcggataat tgtgtcagtg cgtctgccag cttactttcc agctcatccg
     7981 gcgtattaat agccacacca atatggccat aggcttcagc caacttgaca aaatcaggca
     8041 gcgaatccat atacgactga gaatggcggc ctgaataaat catgtcctgc cattgtttca
     8101 ccatccccag atagcggtta ttcaggttta ataccaacac tggcaagtta tattgcagtg
     8161 cggttgataa ctcctgaata ttcatctgga tactgccatc accggtcaca caaacgacgg
     8221 tttcattagg caaagccaat ttaaccccaa gcgccgctgg caagccaaag cccatcgtgc
     8281 ccaagccacc ggagttaatc caacgacgtg gcttatcaaa gggatagtaa agagccgcaa
     8341 acatctgatg ttggcccaca tcagaggtaa cgtacgcatc gcctttagtc agacgatgta
     8401 aggcttcaat caccgcttgt ggcttgattt tcccactgtc tttgttgtag cccaagcaat
     8461 tacgggtgcg ccattgttca atggattgcc accaatcgcg caagctatca aaatcttgtg
     8521 tacagccgac ctgcgacaac aaatctaaca tttgtgtcag tacttgtttg gcatcaccca
     8581 caatcgggat atcggcggtg accgttttcg agatcgatgt cggatcgata tcaatgtgta
     8641 gcactgtggc atcagggcaa tattttgcta aattattggt ggtacgatcg tcaaaacgga
     8701 caccgacggc aaaaatcaga tcagtattgt gcatggccat attggcttca aaggtaccat
     8761 gcatccccaa catgccgaca ctttggcgat gcgtaccagg gaaactgcct agccccatca
     8821 gagagctggt taccggtaag ttcagcttct ctgccaatat cagtaattct tcatggcaag
     8881 cggcgttaat cgcaccacca ccgacataca taatgggccg tttagccgcc ataatcgttt
     8941 gcagtgcacg cttaatctgc ccacggtggc cttgcaccgt aggattatag gagcgcaaac
     9001 tgacttgctc tggataggcg taaggcattt ttactgctgg gccgacaatg tcttttggca
     9061 agtcgataac caccggaccg ggacggccag tggatgccag ataaaaggct tttttcaaca
     9121 ccatcgggat gtcttctgtg cgcttaacca agaagctatg tttgaccact gggcgggaga
     9181 tccccaccat gtcacattct tggaaggcat caaaaccaat caatgagctt ggcacttggc
     9241 ctgaaagcac caccattggc actgaatcca tataggcggt cgcaataccg gtaatcgcat
     9301 tggttgcacc aggaccagac gtgaccagta caacaccgac ctcgcccgtt gcccgcgcat
     9361 aaccatcggc catgtgaacc gcaccttgtt catggcgcac cagcacgtga tcgatgcctc
     9421 cgaccgtgtg cagggcatcg taaatatcaa gtacggcccc gccgggataa ccgaatacat
     9481 gcttaacgcc ctgatcaatt aacgatcgga ccaccatctc ggctcctgac aacatctcca
     9541 tgggttttgc ctccgggctt agtttgctca ttggataacg ggaattcatt tccacgatat
     9601 tctgtaggaa aggcgcaacg cctctttatt cttatttgtg gcttcttact tatttgagcg
     9661 tttttaacgt aacgaattta ttaacataac gtcagaattt ctggcaggca aacagcaatt
     9721 ctccgcacta aagataatta tattggtcac gcgctgaaat tacgtcaatt aaaggaataa
     9781 tcccccagaa aacaagttaa aactggttta taacatcgag gtagtgaatg gttatggaac
     9841 taaatcaggc tgataatttt cactcgttgg attcagtaga atgatgggaa ttacccataa
     9901 ataggtaggt cagggccaaa cacagcagaa cggtcagaaa gacagcagcg accagtgtga
     9961 gacttaacac cggtcactgc ggggaggaat ggtgaacaaa ttaatcgcta tacatcaagt
    10021 caatttcatt ctgatagcgt tgaagaatga ttttccgccg caacttcatc gtaggcgtta
    10081 actcaccggt ttccatagtg aacgcctgag gcaacagcgt aaactttttt acttgctcaa
    10141 acagagccag ctctttttgt atctctttca gccgttgctc aaacatgtta acaatgtggc
    10201 tatggcgcaa tagctccaac cgatcgtgat atttcaagtt gatggatcgg gcatactctt
    10261 ccagcgattc aaaactcggg acaatcaacg ctgatacaaa tttgcgggta tccgcaataa
    10321 tcgctacctg ctcaataaaa cgatcctgtc cgagtgtgcc ttcgatcatt tgtggggcaa
    10381 tatatttccc ccccgacgtt ttcatcaggt ctttcagacg ttcggtaata aacagatgac
    10441 cctgagcatc cagagcaccc gcatcccccg tcttaagcca tccgtcttcg gtaaaggctt
    10501 ctagcgtctc ttgtggcttt ttgaaatagc cacgcatcac gataggccca cgcacctgaa
    10561 tttcattctc tgcccctaag cgaacatcaa tacccggtaa gggcttgccg atagaaccaa
    10621 agcggaagtt ttgctcttcc caacaagaaa ccgtggcaca ggtttcagtc atgccatagc
    10681 cgtatttaat attgacccca atcgcctgga aaaacagaat gatattatca tctaaccgtg
    10741 cgccagccgc gggcagaaaa cgtacccgcc cccctaacac accgcgtaat ttgcgcaata
    10801 ccaaacggtc tgccagtgtg tacatctgct ctgagagcca aggtaatggc cgcccctgct
    10861 gcaaccgttt gaatttacgt tcaccgcacc ccactgccca gtggaatagc acgcgttgat
    10921 gccactttgc caaggcgact ttgtcattaa tcgcgctgaa tactttctcg tagaagcgag
    10981 gcaccgcgca catcaccgtt ggttttactg cctgcatagc agagcgcacc caatccgtat
    11041 tacggatata gacgttctga gcaccggtat gcatcacata gaaactccag gctctttcaa
    11101 aaacatgaga taacggcaaa aaactgaggg acacatcttg tggtgtgagg gttaaccgct
    11161 ggtcatgcaa atagagttga gctgccatat tacggtaatc caacatcacg ccttttggct
    11221 cccccgtggt acccgacgta taaattagcg taaacagatc gtctaaatca cagccttcaa
    11281 tgcgcgtagt taacaggtgc tgttgtacgg tatcgggttg ctgttgctgc tcaaagtcag
    11341 ccaaatgctg ggcgtactca cagccacgta agtccaccgc aggatccaag acgatgatat
    11401 gagccagttg cgggcagaga ggttgcagcg tgatggcaat atcaaattgg gattgctcac
    11461 cgacaaacaa aatccgcaca tcagcatcat tgacgatata ggctgcctga gcggcggtat
    11521 tggtggcata caaggggaca ctaacgccac gtaactgtaa aatagccaga tcgacaagtg
    11581 accacgccat actgttatta gcaaagatgc caatgcgctc ttgtattgca gcccccaaag
    11641 agagcaatgc agtagaaatc cgagtgacat gctcgtcaat ttgctgccag ttgagctgct
    11701 tttcaccctc tggtgaccat tcacgaaagg ctaccagctc tgaacggtca ctgacttgct
    11761 gacgcaacct acgtaccagg tgatattgat gtaatttatg aatcataaag aattaccgct
    11821 cgctggtgaa atatccatta aagtgtgttg caagatttgt acgacaacat tcagcgtaca
    11881 ggtgttcact tttttttcgc gcagtctact cactctgtgc gctatggcaa ataatattcc
    11941 atataagagg taaggttttg atgaaaaaca caacgggctg gacgataaat tagcgggagt
    12001 ctccgtcatc ccatggcatt tcattgaatt gaattgaatt gaactgaact gaacgagcga
    12061 tcatgtgcaa taggcgttgt tgtgtacgct atcagtttcg atgggtaatc atttgtgaca
    12121 aacactctat tttgaaaaac aatctatttc gataaacaat ctattccgaa aaacaatcag
    12181 ttccgaaaaa taatcagttt cgataaacag catacattgc cgtgagcgat gcgatttttt
    12241 gagatgaaaa tatgagatat ggttaggtga atgattgcct gctaccaata acaagatgaa
    12301 ctcagcagca ggacttaatg atcagaactt aatgataaat cattaaacgg gagaactaaa
    12361 ttgcccgagt aacgctttca tccattgatg gcctttatct ctatccgtag attcatgcca
    12421 tgtaaggtaa caggcgcgcg aagtattttc ccaaggtaat gaaattaact ttagattcaa
    12481 cgcctcactg tatgttttta ccaaccagcg gggagcaatt gccacaaaat aagtctgaga
    12541 aacaatattt agcacactgt tcatatcagt actttcataa gcaatagatt gagtactggt
    12601 tgttgagtcg taataaggct cactgaatga ccctttttta tctaatgata caaccgcgtg
    12661 agattcggaa aggagctgat tttcagtaat tgaatcatta atacgtgggt gatctttaga
    12721 aacggccagc actaattcat ctttaaataa agggatgcgg tgaaaatccg ggcggtcgaa
    12781 ctcggtgtag ccgatgacaa actcggtctc ctgataacgt agttgatgct caatgttgtc
    12841 attaagataa gatttgatga ccagttgaac attaggcgct gattgtttta cccgctgtac
    12901 aatctgagcc gccagtcgaa catctaacgg gctacaaatc gatagattaa acagccgttc
    12961 actgtttttc gcttcaaacc ctgcaccggg taactcattt tgtactaact gcaatgcctg
    13021 gcgtaccggc ccgaagagct gacgggctct ggctgtaggc tgtatgccac gaccataacg
    13081 gacaaagagc tcatcattga acatgacttt caaacgggca acagcattac ttacagcagg
    13141 ctgggacata ccaagagact gtgccgcacg tgtcacattt tgcatttgca tcacagcatc
    13201 gaaaacagtt aacaaattta ggtcgacact tcttaaatgg acatcgatag attctttttt
    13261 agttgcttga ctgtcagtta ctaagttgta ttcagacatg cttaactcca ctaagcttta
    13321 tgcagatggc gcgattaata aaaggacttc tctgatattg atataccctt attcttcaac
    13381 gttgctcgtg ccgctcactg acgtgagcta gcgcatcaaa attcgctcat tatttcttgc
    13441 tgtaacacca atggctatgg gtagacgctg ttgcaatatc cttaatctct tactattaat
    13501 aacgccaatg ttctcttgta ttacctttgt agggtaaatt tgagtttcat ccttgtataa
    13561 atgtgagata cggttcacac ctaatgcatt ctgttgtcag taattctcca taaaaaacac
    13621 ataaacaaaa aacctataca aagtcattta tatagccacc acaacaaatt tatattagta
    13681 atataaaaat tttaattata atcaccaata ataaaattaa cgagatgatc acatcacaaa
    13741 atgagatgat tgacaactat gccattaata aataataaat tcatcaatta aaacttatca
    13801 tttcttaatt ttacgcagaa actcattgaa taatttaaag cacttcattt tatttaatta
    13861 taattaattg atttagtcac aaaatatcaa gactataaat atacaactca tataaaaata
    13921 gttactaatc tttaataagc atcataaaaa aaaatggata aagggcgata tcttacatgg
    13981 atcaatttat cttatacatc tcaacactgc ccctatcact ctcattaact cataaaaaaa
    14041 tcgaatcaaa taggcaaaac aatcagcatt catgttgggt tgggcgacaa gccgccgcgg
    14101 agaaacacgg aaagcacaat aacccagata atggtaatta tgccaaacaa ttaaaaaatc
    14161 atgagcgact tgttcaggac aatactctgt aaaaatgatt attttggatt ttagctccaa
    14221 ttaaaagaag tcggaattcg ctcaaccagt tgaagtcgcc attttaaaca attgttgaca
    14281 caaacataga attcacgtat caatttaggc aacgcaatat tttcactgat gagaagctga
    14341 aatttatgtt ctactcaacc cgtctactaa gcctactact taacgcatct ctcttgcgcg
    14401 gtatgttggt ggacggaaat cagaactgat tcagccatca agattaacaa gcccgcgcaa
    14461 atgcgcgggt tttttttgtg cccagaaaac ccccagctag gctgggggtt cagtaaagct
    14521 ttcagctttg ggtcagttat aaaaacccct tttgatttgt taaaacagtt tgcggtctgg
    14581 caactgcaaa tgttcaacaa gaaatcaaaa gggggtccca atgagggatg aaaagagctt
    14641 agcgcacacc cgatggaact gtaaatatca tatagttttt gcgccgaagt accgaaggca
    14701 ggtgttctac agggaaaaac gcagagcgat tggcagtatt ttaagaaaac tgtgcgaatg
    14761 gaaaaacgtg aatatcctgg aagcagaatg ctgtgtggat cacatccata tgcttctgga
    14821 gatcccgccc aagatgagtg tctcgggatt tatggggtac ctgaagggaa agagcagtct
    14881 gatgctttat gagcagtttg gcgatttgaa gttcaaatac cgtaacaggg agttttggtg
    14941 tcgagggtat tacgttgata cggtagggaa aaacacggcc aggatacaag aatacataaa
    15001 gcaccaattg gaagaggata aaatgggtga gcaactctcg atcccgtatc ccggtagccc
    15061 gtttacgggc cgtaagtaat ccatagatgc aaatgtcaga tcgcgatgcg cctgttaggg
    15121 cgcggctggt aacagagcct tataggcgca tatgaaaaac ctccggctat gccggaggat
    15181 atttatttta tccgctgagc gcaaatgtaa aaaaaggaac aacccatgag ccaacaagtc
    15241 attatttttg atacaacatt gcgcgacggt gaacaagcat tgcaagccag tctgagtgtg
    15301 aaagagaagc tgcaaatcgc gctggcattg gaaagaatgg gggtcgatat catggaggtg
    15361 ggtttccctg tctcctcccc tggtgatttt gaatcggttc gtactatcgc tcagcaagtg
    15421 aaaaatagcc gggtttgcgc cttggcacgt tgtgtggata aagatattga tgttgcggca
    15481 gaggcattgc gaattgcaga agctttccgt attcatgtgt ttttggccac ctcaaccttg
    15541 catatcgaat ccaagttaaa gcgttcgttt gacgatgtgc tggcgatggc ggtccactcc
    15601 gtgaaacgtg ctcgtaacta taccgatgac gtcgagtttt cttgtgaaga tgctggccgt
    15661 actccaattg ataacttatg ccgtgtcgtc gaggccgcga ttaccgccgg tgccaccaca
    15721 atcaatatcc cggataccgt cggttacacc accccttatc aatttggtgg catcatcact
    15781 gacttgtatg aacgtgttcc caatattgat aaagccatta tctctgttca ttgccatgat
    15841 gacttgggca tgtccgttgc caactccatt actgcagtac aagccggggc gcgtcaggtc
    15901 gaagggacca tcaacggctt aggtgagcgt gcaggtaact gttcattgga agaggtgatc
    15961 atggccatta aagtgcgcca tgaaatgttg ggcgtgcaca ccaatatcaa tcatcaggaa
    16021 atttaccgta ccagccagtt ggtcagtaaa atttgcaata tgcctattcc cggcaataaa
    16081 gccattgtcg gcagtaatgc cttcgctcac tcctccggta ttcatcagga tggtgtcctg
    16141 aaaaatcgcg aaaactacga aatcatgacc ccggaatcca tcggtctgaa agaagtccaa
    16201 ttgaacctga catcccgttc aggtcgtgcg gcagtgaagc accggatgga agagatgggt
    16261 tatcaggata aagattacaa tttagattct ttgtacgatg ccttcttgaa attagccgat
    16321 aaaaaaggcc aggtctttga ctacgatttg gaagcattgg cctttattaa taagcagcag
    16381 gaagagcctg aatattatcg tttggactat ttcagcgtcc agtcgggttc cagtgtcatg
    16441 gcaactgcct cagtaaaatt ggtctgtggt gaagaaataa aatcagaagc ggccaccggt
    16501 aacggcccgg ttgatgcggt gtatcaggcc atcaatcgca ttaccgacta cccaattgaa
    16561 ctggtgaagt atcaactgtc ggccaaaggt cagggtaaag atgcattggg tcaggttgat
    16621 atcgtggttg accacaaggg gcgtcgcttc catggcgtag gtttggcaac tgacattgtt
    16681 gagtcatccg ctaaggcgtt ggttcacgta ttaaataaca tctggcgcgc ccatcaggtc
    16741 gaaaaagaga agcagcgtct gcaacaaaat aatcaggaaa tggtgtgaac atgacgaaga
    16801 cttatcatat tgcagtgttg cccggcgacg gtatcggccc tgaagtaatg gctcaggcaa
    16861 gtaaagtatt agatgcggtg cgtcagcgct tcggtctcaa gatttcaacc agtgtttacg
    16921 atgttggtgg cgctgccatt gaccgccatg gtagcccatt accggcagca acggtcgcgg
    16981 gatgtgaaca ggcagatgcc attttatttg gctccgtagg cggcccaaaa tgggaacacc
    17041 tgccaccggc agaacaacct gagcgtggtg ccttattgcc tttgcgtaaa catttcaaat
    17101 tattcagcaa tttgcgccct gcccgtttgt atcaaggatt ggaggacttc tgtccattgc
    17161 gcagtgatat cgcggccaga ggttttgata tcctgtgtgt ccgtgaatta accggcggta
    17221 tctatttcgg ccagccgaaa ggccgtgaag gccaaggcat gcacgagcgg gcctttgaca
    17281 ccgaagttta tcatcgcttc gaaattgaac gtatcgcccg tattgctttc gaatcagccc
    17341 gcaaacgccg tagtaaagta acgtccattg ataaagccaa cgtgttgcaa agttcaatct
    17401 tgtggcgtga agtggtcaac gggatcgcgg cggattaccc agatgttgcg ttgtcccata
    17461 tgtacattga taacgccacc atgcagttaa tcaaagaccc ttcccaattt gacgtgttgc
    17521 tgtgctctaa cttgtttggc gatatcttgt ccgatgaatg cgccatgatc accggctcca
    17581 tgggcatgtt gccatcagcc agtttgaatg aacaaggttt tggtctatat gaacccgcag
    17641 gcggttccgc accggatatc gcgggtaaga acattgccaa ccctatcgct cagatcctgt
    17701 cattaaccct gttgctgcgt tttagcttag gtaaagatga tgccgctgac gccattgagc
    17761 gcgcgatcaa ccaggcattg gagcaaggtt atcgcactgc ggatttagcc ggggatggtc
    17821 acgcaatcgg cactcacgaa atgggcgata tcatcgctaa attcgtggtt gaaggggtat
    17881 aaaatgggca caacatcatc tcagagcaaa acgttatacc aaaaattgta cgatgcgcac
    17941 attgtgcatg aagcccccaa tgagacccca ttgctgtata tcgaccgcca tttagtgcat
    18001 gaggtcacct caccgcaagc ctttgatggt ttgcgtgcca tgggccgccc ggtgcgtcaa
    18061 ccgggtaaga ctttcgctac catggatcac aacgtttcta cccaaacaaa agacattaac
    18121 gccagtggtg agatggcccg tattcagatg caagagttaa ttaaaaactg cgctgaattc
    18181 ggtgtctcat tgtatgacct gaaccaccct ttccaaggga tcgtgcatgt cattggccct
    18241 gagcaaggca tgacgttacc gggcatgacc atcgtttgtg gtgactcaca taccgccact
    18301 cacggcgcat tcggctcctt ggcctttggt atcggcacct cagaagttga gcatgtgttg
    18361 gcgacccaaa ccctgaagca ggggcgagcc aaaaccatga gaatcgaagt gaatggcact
    18421 gtcggcgcgg gtattacggc taaagacatc gtgctggcga ttatcggtaa aaccgggagc
    18481 gcaggcggta ctggccatgt ggtggagttc tgtggcagcg cgattgaagc gttgagcatg
    18541 gaaggccgga tgacattatg caacatggcg atcgaaatgg gggccaaagc cggtttggtt
    18601 gcccctgatg acaccacctt tgcctatctg aaaggccgtc agttcgcccc aactggcgag
    18661 caatgggaac aaggtgttgc ctactggcgt accctgaaat ctgatgctga tgcccaattc
    18721 gataccatcg tgacactgga tgccgctgat atcgcgccac aggtgacgtg gggaaccaat
    18781 ccgggtcagg tcattgcggt taatcaaatc attcctgccc ctgagtcttt cagcgatccg
    18841 gtcgaacgtg catcagcaga gaaagcctta gcttatatgg acttgcgccc cggcattaaa
    18901 ttgactgaag tggcgattga taaagtcttt atcggctctt gcactaactc acgtattgaa
    18961 gatttacgtg cggcagcggc tattgcccaa gggcgtaaag tcgccaaggg tgtgcaagct
    19021 atcgtggtgc caggctccgg cccggtgaaa gcgcaggcag aagcggaagg tttggataag
    19081 atctttatcg ccgcaggttt tgagtggcgt ctgcccggtt gctcgatgtg tttggccatg
    19141 aataatgacc gcctggagcc cggcgaacgt tgtgcctcca ccagcaaccg taattttgaa
    19201 ggccgccaag gccgtggggg gcgcacacat ttggtcagcc cagccatggc cgccgctgcc
    19261 gccgtcagtg gtcattttgc tgatgttcgc gaattatccg ccaccaccca ctaaccggag
    19321 acaccaccat ggcaaaattt attcaacaca ttggtttggt tgcgccgtta gatgcagcaa
    19381 acgtcgatac cgacgcgatt atccctaagc agtttttgca aaaagtgact cgcacgggct
    19441 ttggtcaaca cctgtttaac gattggcgtt ttttggatga tgccggcaag gtaccgaatc
    19501 ctgattttgt cctgaacctg cctcgctatc agggtgccac tattttgtta gcccgtgaga
    19561 attttggctg tggctcctca cgtgaacacg caccatgggc gctgacggat tttggtttta
    19621 aagtggttat cgccccgagt tttgctgata ttttttatgg taacgcgttt aataaccaat
    19681 tattaccggt gacattaagc gaagcggata ttgatacctt attccaattg gttaaagaga
    19741 atgaaggtat tgagtttgtg gttgatctcg agcagcaaac ggttaatgcc ggtggcaaaa
    19801 gctatgcttt cgaaatcgat cctttccgcc gccactgtat gattaatggg ttggatagca
    19861 ttggcttgac gttgcagcat gaacacaata tctcagcata cgaaaaacaa cagcctgaat
    19921 ttctacgtta aataaccgtt aaggccagca gaactaacat gccagcctgt ttagtaaata
    19981 tatcgttatt tttagtagta atagattgtg agtcattaat agattgtaag taactaatag
    20041 attgttggtg ccgggtcgta ccggcccaac aagtaacacg tttaactcat cctaccgcca
    20101 gctgaccccc gccgcttctg gcacaaagca ggggcaaacc gctaagctgc gctgacctaa
    20161 accgctctca cctaagcctc tctcactttg gcgcagatga tcaacgccaa aataaccaac
    20221 accatcgcag cgacataaac cgcattatgc ccccaggttt cagtcaatac accttgcagc
    20281 acaccggcca aaatcacccc actagaaata ctgttggtaa ataacgtggt tgcggcacct
    20341 gcccgccccg gcatgagatc ctgaaaatag agcataccaa taccggcgac gatgccgata
    20401 aagatggcat taaaaatctg caattgtaac gaacggtgca atagtgatcc acacccaacg
    20461 cctgaaatca gatccagggg gtaatctgct ctcctgattc aggagagttt atggtcactt
    20521 ttgagacagt tatggaaatt aaaatcctgc acaagcaggg aatgagtagc cgggcgattg
    20581 ccagagaact ggggatctcc cgcaataccg ttaaacgtta tttgcaggca aaatctgagc
    20641 cgccaaaata tacgccgcga cctgctgttg cttcactcct ggatgaatac cgggattata
    20701 ttcgtcaacg catcgccgat gctcatcctt acaaaatccc ggcaacggta atcgctcgcg
    20761 agatcagaga ccagggatat cgtggcggaa tgaccattct cagggcattc attcgttctc
    20821 tctcggttcc tcaggagcag gagcctgccg ttcggttcga aactgaaccc ggacgacaga
    20881 tgcaggttga ctggggcact atgcgtaatg gtcgctcacc gcttcacgtg ttcgttgctg
    20941 ttctcggata cagccgaatg ctgtacatcg aattcactga caatatgcgt tatgacacgc
    21001 tggagacctg ccatcgtaat gcgttccgct tctttggtgg tgtgccgcgc gaagtgttgt
    21061 atgacaatat gaaaactgtg gttctgcaac gtgacgcata tcagaccggt cagcaccggt
    21121 tccatccttc gctgtggcag ttcggcaagg agatgggctt ctctccccga ctgtgtcgcc
    21181 ccttcagggc acagactaaa ggtaaggtgg aacggatggt gcagtacacc cgtaacagtt
    21241 tttacatccc actaatgact cgcctgcgcc cgatggggat cactgtcgat gttgaaacag
    21301 ccaaccgcca cggtctgcgc tggctgcacg atgtcgctaa ccaacgaaag catgaaacaa
    21361 tccaggcccg tccctgcgat cgctggctcg aagagcagca gtccatgctg gcactgcctc
    21421 cggagaaaaa agagtatgac gtgcatcttg atgaaaatct ggtgaacttc gacaaacacc
    21481 ccctgcatca tccactctcc atctacgact cattctgcag aggagtggcg tgatgatgga
    21541 actgcaacat caacgactga tggcgctcgc cgggcagttg caactggaaa gccttataag
    21601 cgcagcgcct gcgctgtcac aacaggcagt agaccaggaa tggagttata tggacttcct
    21661 ggagcatctg cttcatgaag aaaaactggc acgtcatcaa cgtaaacagg cgatgtatac
    21721 ccgaatggca gccttcccgg cggtgaaaac gttcgaagag tatgacttca cattcgccac
    21781 cggagcaccg cagaagcaac tccagtcgtt acgctcactc agcttcatag aacgtaatga
    21841 aaatatcgta ttactggggc catcaggtgt ggggaaaacc catctggcaa tagcgatggg
    21901 ctatgaagca gtccgtgcag gtatcaaagt tcgcttcaca acagcagcag atctgttact
    21961 tcagttatct acggcacaac gtcagggccg ttataaaacg acgcttcagc gtggagtaat
    22021 ggccccccgc ctgctcatca ttgatgaaat aggctatctg ccgttcagtc aggaagaagc
    22081 aaagctgttc ttccaggtca tcgctaaacg ttacgaaaag agcgcaatga tcctgacatc
    22141 caatctgccg ttcgggcagt gggatcaaac gttcgccggt gatgcagcac tgacctcagc
    22201 gatgctggac cgtatcttac accactcaca tgtcgttcaa atcaaaggag aaagctatcg
    22261 actcagacag aaacgaaagg ccggggttat agcagaagct aatcctgagt aaaacggtgg
    22321 atcaatattg ggccgttggt ggagatataa gtggatcact tttcatccgt cgttgacagc
    22381 aatatcatca gtgcggtttt gaatttaaac agcaccagcc cggtataaaa cagcaccccc
    22441 gccatcaccg caaacagcat gattttacgt ttaccaaagc gcctaaccga gtaacctgcc
    22501 aacaacatga taggaatttc cagcccggcg gcggtcccca tcagcaaacc cgccaaacgc
    22561 tcaggcaacc ctaaattagc ggtgatatag agcggcatat caatgatgta catggtatta
    22621 cacgtccaca tcagcattga ggcaatgaac agcagtaaga catttttatc ggcaaacaaa
    22681 ctgccttgta ccaccacggg ggcatcggct acgggctcag gctgtttaac cgacggcagg
    22741 ataaaccaga ccaccagcgc actaataaca aaaataccgg cggcaatgct aaacatcagc
    22801 gtaaagccat aattcagcgc taacataaat gacagcggtg gcccgataac ccaagccaat
    22861 gataattgcg cacgcataat cgaactgaac atcaccactt cacgcgcaga gttatccgca
    22921 tattcccgtg ccaaggcgaa aatttgcggc atcgcggtat tcgccaccga ggccatcaaa
    22981 acacctaaag tgatcaacgt cagataatca cgattaaaag cgaatagcag gcaatttccg
    23041 accgccatca gatagcagat cagaattaat ttacgccgat ccccgcccag atctgagcgt
    23101 ttggccagta ggaagctcac ggtgataccg gcaatggcat tcacggtata aaacaatccg
    23161 acccacagcg gacgcacttt taactctgtg cttaaaaaca ggcttaatgt cggggcttgc
    23221 aacgcacccg cgatgccgga aagaaaagcc accacaaaga aagcgaggaa aaccgggttg
    23281 atacgacggg aaaaggctcg tgcagatctc attccaggct ccagcgccag aaaaagctat
    23341 tattagcata atcataatgg tgccctatgc tacagaagct cttatacata aagaagtgat
    23401 ataggctttt atctattcaa agtcattggc gttgcagatg gagtagccag caaacaaccc
    23461 ccgatgaggc taattatctt aaggtcaacg accagtcagt gattcgggtg agtgcgtgca
    23521 gctaacaacc ctgcagcgtc aaggccgaag ggatttcccc aaagtcattg gcgttgcagg
    23581 taggcagcca gcaaacgaca aattggttca accattttga acagcgcttg cgctggcccg
    23641 cagggtgaga ctctgatgag gctcataatc ccgatgaggc taattatctt aaggtcaacg
    23701 accagtaagt gattcgggtg agtgcgcgca gctaacaacc ctgcagcgtc aaggccgaag
    23761 gggaaaaaga aaaaagccag cagaaaaacc tactggctgg tgaaaaacac cattactcag
    23821 aatttttttg gtacttggta ggacaaggct caactcatta ctttcggctg tgactgcata
    23881 gacgttgtca cgataacccg cttttcttgg gggttagtat ctgcgtaata tagggaaaga
    23941 aaaattgatg agatttccca aggagttcct cttttatgtc tacctcgcgc ctgcaacaac
    24001 aatttattcg tctctggcaa cgctataacg gacagtcaac ggaaaccaca ttgcaggcgc
    24061 tggctgaagt gctgaattgt tcacgccgcc atgtacgttc tctgctgggc aagatgcagc
    24121 acgcgggctg gctcgattgg caggctgaag ctggccgagg aaaacgctca caattgatct
    24181 tcttgcgttc cgggctggcg ctgcaacaac aacgggctga agagttgctg gagcaggatc
    24241 atattgatca gttagtccaa ctggtcggtg ataaaaaagc ggtacgccaa atgttgctgt
    24301 cccagttggg acgtagcttc cggcaaggaa aacatattct gcgggtgctc tattaccgcc
    24361 cattggagaa cttattaccc ggcaccgccc tacgccgctc tgaaacccat atggtgcggc
    24421 aaatttttaa cgggctgaca cggataaatg aggaaaatgg ggaactcgaa ccggacttat
    24481 ctcatcactg gcaagcgatc acccccttgc attggcgctt ttatttgcga ccagccattc
    24541 atttccacca tggccgggaa ctggaaatga gtgatgtgat tagcagcctg acccgcctga
    24601 tcccccaacc cctgttttct catattgcgg aggtgcgttc accgacacct tatgtgattg
    24661 atgtttatct ccattcgcca gatcactggt tgccatggct actgggcagc gttcacgcca
    24721 tgattttgcc gcaagagtgg gaaactcagc ccgattttca ccgacagcct attggtaccg
    24781 gcccttattc cgtgatccgc aatcatcaca gccagctgaa aattcaggca ttcgataact
    24841 attttggttt ccgggcactg attgatgagg tcaatatctg ggtactccca gaactctccg
    24901 aagaattggt gtattccggg gtgcaattgc aagccgacga tacgggtaaa aatgagctgg
    24961 agagccgttt agaggaaggt tgctacttct tactgttcga ccaacgatcc cctcaggcct
    25021 gcaccccgga gatccgccgt tggttatgtg aattgatcac accgatagcg ttactcagcc
    25081 acgccgctcc cttctatcaa cgttactggt caccggccta tggcatgttg ccacgctggc
    25141 accataaccg actcaccact caagagccaa aacccgaagg gctgaacgag ctgacactga
    25201 cgttttacag cgaacattca gagtttgatg ccatcagcca gacactgacc cagttattgg
    25261 ctgctcaggg cgtgacgtta aagatacaag tcttggacta cacccgctgg tatcaggggg
    25321 atgcacaaag cgatatctgg ctcggcagcg ctaactttta cttgccactc gaattctcgc
    25381 tatttgccac cctctatgaa atgccgctac tacaacattg tctgagcgaa gaactgcatc
    25441 aagatattga atcctggcgc aataatacct tactcatggc cgattggagc caacgactgg
    25501 taagccagca tcaattccat ccgctatttc atcattggtt agaattatac ggtcaacaca
    25561 gtatgcgggg agtgcgtatg aatacactcg gctggtttga ttttaaatcc gcatggttta
    25621 ccccaccaga ggcctagggc ggcgttgact cacacggcgc tccccctgaa tttattatac
    25681 aaacgggctg cactacccct ttcaataatt ccatttatga gaacgagtta aatactctca
    25741 ttttttattg taaagttttt tatatgcgat gataaaagga atagcataag aatatgaaaa
    25801 caaaagagtt atataatgta gaaagtcatt atcctctgta tttataccaa acaagggtat
    25861 tctatctgaa ataaatgcac tgtaatgaaa aatagaaaat aggcaggtaa aagccagcga
    25921 gctaatattc aaataaatat ttttagaata aagaagatga cttactacat aatagtaaaa
    25981 aaatagcgat actactgaca gtgaaatata taaccatgcc atagacagtc ctcagtaaga
    26041 tctatattgt ccatagatcg tgtttgcatc accagtcaat tcaatgaaaa gttctggccc
    26101 actcatgatt tttatacctt gctgctttag tcctgagaga agaccggcat caatatagcg
    26161 gtatatatcc ctacaaacac tacccctccc cacaaacatc gccctttcac cggcttagat
    26221 taaactctac aatggcgtcg tctcaacggg gtgcaaaata ttgccagctt ggtttaactc
    26281 ggtctcgcag gtgtcaaaac acagcgagcg gggttatgac cgtggcgaac agcgcggagt
    26341 gaccggtaca tacaccatga ctttatcaat catggcgatg cgcggatcac ccagactgct
    26401 caacactgga accacctaac cgccgcaatt tttttcgctg agagtaaacc cgtcgaacct
    26461 gatccggtta accccggcgg agggatttga gaatgataac gactgtatca tcacggatac
    26521 caatgttaac taccgcctca gatacctttg ccacctttat gttcaaggag tgcaaagtgt
    26581 ttaaacacat tatttcctgc ttattactga tatcagccac ctccgcgctt gccgcagaaa
    26641 aacctacgct gacggtctat acctacgact cctttgctgc tgactggggc ccaggcccgg
    26701 cgattaagca ggcctttgaa gctgaatgcg attgccagct aaaatttgtg gcactggaag
    26761 atggcgtttc actgctgaac cgcctgcg
//
