LOCUS       NZ_CP046293.1          25871 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP046293.1 Yersinia intermedia strain FDAARGOS_730 chromosome,
            complete genome.
ACCESSION   NZ_CP046293
VERSION     NZ_CP046293.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:59:39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3870705
            Orig. end    :: 3896576
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25871
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[3880705:3886576]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15871
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..25871
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25871
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="6"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(982..2745)
                     /locus_tag="ctg1_3560"
                     /transl_table=11
                     /translation="MKAARPGKLKRQEEQASFISWRFALLCGCILLALVGLMLRTAYLQ
                     VINPDKLVREGDMRSLRVQEVPTARGMISDRSGRPLAVSVPVNAVWADPKELTERGGIT
                     LDTRWKALSDALEIPLDQLATRINANPKGRFVYLARQVNPAIGDYIHKLKLPGIYLRQE
                     SRRYYPAGQVMAHIIGVTNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIEDISS
                     VDSQAAHNLVLSVDERLQALVYRELNNAVAFNKAESGTAVLVDVSTGEVLAMANSPSYN
                     PNNLTGTPKDAMRNRAITDIFEPGSTVKPMVVMTALQHGVVKENSVLNTLPYFVNGHQI
                     KDVARYAELSVTGILQKSSNVGVSKLALAMPSSALVDTYSRFGFGKATNLGLVGESSGL
                     YPKKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSMGIYRPLSITKVDPPVAGERIF
                     PEPLVRTVVHMMESVALPGGGGTKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGV
                     APASNPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPDALPTGDKSELV
                     INTKEGSGGRS"
     PFAM_domain     complement(1087..1971)
                     /aSDomain="Transpeptidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00905.24"
                     /description="Penicillin binding protein transpeptidase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3560_0126"
                     /evalue="5.40E-81"
                     /label="ctg1_3560"
                     /locus_tag="ctg1_3560"
                     /protein_end="553"
                     /protein_start="258"
                     /score="272.2"
                     /tool="antismash"
                     /translation="GTAVLVDVSTGEVLAMANSPSYNPNNLTGTPKDAMRNRAITDIFE
                     PGSTVKPMVVMTALQHGVVKENSVLNTLPYFVNGHQIKDVARYAELSVTGILQKSSNVG
                     VSKLALAMPSSALVDTYSRFGFGKATNLGLVGESSGLYPKKQRWSDIERATFSFGYGLM
                     VTPLQLARVYATIGSMGIYRPLSITKVDPPVAGERIFPEPLVRTVVHMMESVALPGGGG
                     TKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGVAPASNPRFALVVVINDPQAGKY
                     YGGAVSAPVFGAIM"
     PFAM_domain     complement(2089..2547)
                     /aSDomain="PBP_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03717.17"
                     /description="Penicillin-binding Protein dimerisation
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3560_0125"
                     /evalue="6.30E-18"
                     /label="ctg1_3560"
                     /locus_tag="ctg1_3560"
                     /protein_end="219"
                     /protein_start="66"
                     /score="65.8"
                     /tool="antismash"
                     /translation="PTARGMISDRSGRPLAVSVPVNAVWADPKELTERGGITLDTRWKA
                     LSDALEIPLDQLATRINANPKGRFVYLARQVNPAIGDYIHKLKLPGIYLRQESRRYYPA
                     GQVMAHIIGVTNIDGQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIED"
     CDS             complement(2807..3127)
                     /locus_tag="ctg1_3561"
                     /transl_table=11
                     /translation="VIGNERHGLVGVISGDLIRNAKIPLILLIAVLVSAVFVVTTAHRT
                     RLLTAEREQLVLERDALDIEWRNLILEENALGDHSRVESIATDKLKMQHVDPSQENIVV
                     KQ"
     PFAM_domain     complement(2816..3097)
                     /aSDomain="FtsL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04999.15"
                     /description="Cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3561_0127"
                     /evalue="7.00E-35"
                     /label="ctg1_3561"
                     /locus_tag="ctg1_3561"
                     /protein_end="104"
                     /protein_start="10"
                     /score="119.0"
                     /tool="antismash"
                     /translation="GVISGDLIRNAKIPLILLIAVLVSAVFVVTTAHRTRLLTAEREQL
                     VLERDALDIEWRNLILEENALGDHSRVESIATDKLKMQHVDPSQENIVV"
     aSDomain        complement(2819..3064)
                     /aSDomain="TIGR02209"
                     /aSTool="tigrfam"
                     /description="ftsL_broad: cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3561_0033"
                     /evalue="1.20E-27"
                     /identifier="TIGR02209"
                     /label="ctg1_3561"
                     /locus_tag="ctg1_3561"
                     /protein_end="103"
                     /protein_start="21"
                     /score="93.6"
                     /tool="antismash"
                     /translation="KIPLILLIAVLVSAVFVVTTAHRTRLLTAEREQLVLERDALDIEW
                     RNLILEENALGDHSRVESIATDKLKMQHVDPSQENIV"
     CDS             complement(3124..4086)
                     /locus_tag="ctg1_3562"
                     /transl_table=11
                     /translation="MVDNNKIVDNNYKHTSVLLDEAVNGLNIRDNGIYIDGTFGRGGHS
                     RLILSQLGPEGRLIAIDRDPQAIEAAKSITDPRFSIVHGPFSELAHYVRELDLVGRIDG
                     VLLDLGVSSPQLDDPERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFG
                     EERFAKRLAKAIVERNLTQPMTRTKELADLIANASPFREKHKHPATRSFQAIRIYINSE
                     LEEIERALDGALEVLAPAGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLR
                     SMGGRTLKSAGKMMPPDAEVAENPRARSSVLRFAERIKE"
     PFAM_domain     complement(3136..4053)
                     /aSDomain="Methyltransf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01795.21"
                     /description="MraW methylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3562_0128"
                     /evalue="3.20E-115"
                     /label="ctg1_3562"
                     /locus_tag="ctg1_3562"
                     /protein_end="317"
                     /protein_start="11"
                     /score="385.0"
                     /tool="antismash"
                     /translation="YKHTSVLLDEAVNGLNIRDNGIYIDGTFGRGGHSRLILSQLGPEG
                     RLIAIDRDPQAIEAAKSITDPRFSIVHGPFSELAHYVRELDLVGRIDGVLLDLGVSSPQ
                     LDDPERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLAKA
                     IVERNLTQPMTRTKELADLIANASPFREKHKHPATRSFQAIRIYINSELEEIERALDGA
                     LEVLAPAGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKSAG
                     KMMPPDAEVAENPRARSSVLRFAER"
     aSDomain        complement(3136..4059)
                     /aSDomain="TIGR00006"
                     /aSTool="tigrfam"
                     /description="TIGR00006: 16S rRNA
                     (cytosine(1402)-N(4))-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3562_0034"
                     /evalue="1.70E-125"
                     /identifier="TIGR00006"
                     /label="ctg1_3562"
                     /locus_tag="ctg1_3562"
                     /protein_end="317"
                     /protein_start="9"
                     /score="416.6"
                     /tool="antismash"
                     /translation="NNYKHTSVLLDEAVNGLNIRDNGIYIDGTFGRGGHSRLILSQLGP
                     EGRLIAIDRDPQAIEAAKSITDPRFSIVHGPFSELAHYVRELDLVGRIDGVLLDLGVSS
                     PQLDDPERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLA
                     KAIVERNLTQPMTRTKELADLIANASPFREKHKHPATRSFQAIRIYINSELEEIERALD
                     GALEVLAPAGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKS
                     AGKMMPPDAEVAENPRARSSVLRFAER"
     CDS             complement(4089..4547)
                     /locus_tag="ctg1_3563"
                     /transl_table=11
                     /translation="MFRGATMVNLDSKGRLAVPTRYRDLLNEESQGQMVCTIDLHQPCL
                     LLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGL
                     NKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQDLSL"
     aSDomain        complement(4092..4547)
                     /aSDomain="TIGR00242"
                     /aSTool="tigrfam"
                     /description="TIGR00242: division/cell wall cluster
                     transcriptional repressor MraZ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3563_0035"
                     /evalue="1.40E-63"
                     /identifier="TIGR00242"
                     /label="ctg1_3563"
                     /locus_tag="ctg1_3563"
                     /protein_end="152"
                     /protein_start="0"
                     /score="211.1"
                     /tool="antismash"
                     /translation="MFRGATMVNLDSKGRLAVPTRYRDLLNEESQGQMVCTIDLHQPCL
                     LLYPLPEWEIIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGL
                     NKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQDLSL"
     PFAM_domain     complement(4122..4319)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3563_0130"
                     /evalue="1.90E-20"
                     /label="ctg1_3563"
                     /locus_tag="ctg1_3563"
                     /protein_end="142"
                     /protein_start="76"
                     /score="72.7"
                     /tool="antismash"
                     /translation="LLGHASECQMDGAGRLLIAGTLRQHAGLNKEVMLVGQFNKFELWD
                     EQTWYQQVKDDIDAEQSTQEP"
     PFAM_domain     complement(4323..4547)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3563_0129"
                     /evalue="9.90E-24"
                     /label="ctg1_3563"
                     /locus_tag="ctg1_3563"
                     /protein_end="75"
                     /protein_start="0"
                     /score="83.2"
                     /tool="antismash"
                     /translation="MFRGATMVNLDSKGRLAVPTRYRDLLNEESQGQMVCTIDLHQPCL
                     LLYPLPEWEIIEQKLSRLSSMNPAERRVQR"
     CDS             5470..5910
                     /locus_tag="ctg1_3564"
                     /transl_table=11
                     /translation="MFSTGSRLRSAAADTFALVVYCFVIGMIIEIVISGMTFQQSLSSR
                     LVSIPVNILIAWPYGVYRDAFIRFARHHADKHSWARNLADLLAYVSFQSPVYAIILWSV
                     GADLEQITTAVTSNALVSMAMGVAYGYFLEYCRRLFRVAGYV"
     PFAM_domain     5482..5895
                     /aSDomain="AlaE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06610.15"
                     /description="L-alanine exporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3564_0131"
                     /evalue="5.60E-72"
                     /label="ctg1_3564"
                     /locus_tag="ctg1_3564"
                     /protein_end="142"
                     /protein_start="4"
                     /score="240.5"
                     /tool="antismash"
                     /translation="GSRLRSAAADTFALVVYCFVIGMIIEIVISGMTFQQSLSSRLVSI
                     PVNILIAWPYGVYRDAFIRFARHHADKHSWARNLADLLAYVSFQSPVYAIILWSVGADL
                     EQITTAVTSNALVSMAMGVAYGYFLEYCRRLFRV"
     CDS             complement(6058..7062)
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 208.2; E-value: 3.2e-63)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3565"
                     /transl_table=11
                     /translation="VKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREH
                     NYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPD
                     NEMRCIEHLLQRQVDAIIVSTALPPEHPFYQRWANDPLPIIALDRALDREHFISVVGAD
                     QEDALMLAQELRAFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVDYLYANSYER
                     EAAGVLFAQWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPSNLAIATFGDNELLDF
                     LECPVLAVAQRHRDVAERVLELVLASLDEPHKPKPGLTRIRRNLFRRGSLSRK"
     aSDomain        complement(6079..7059)
                     /aSDomain="TIGR02417"
                     /aSTool="tigrfam"
                     /description="fruct_sucro_rep: D-fructose-responsive
                     transcription factor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3565_0036"
                     /evalue="3.40E-149"
                     /identifier="TIGR02417"
                     /label="ctg1_3565"
                     /locus_tag="ctg1_3565"
                     /protein_end="328"
                     /protein_start="1"
                     /score="494.4"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREHN
                     YHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDN
                     EMRCIEHLLQRQVDAIIVSTALPPEHPFYQRWANDPLPIIALDRALDREHFISVVGADQ
                     EDALMLAQELRAFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVDYLYANSYERE
                     AAGVLFAQWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPSNLAIATFGDNELLDFL
                     ECPVLAVAQRHRDVAERVLELVLASLDEPHKPKPGLTRIRRNLFRR"
     PFAM_domain     complement(6151..6879)
                     /aSDomain="Peripla_BP_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00532.23"
                     /description="Periplasmic binding proteins and sugar
                     binding domain of LacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3565_0133"
                     /evalue="1.40E-13"
                     /label="ctg1_3565"
                     /locus_tag="ctg1_3565"
                     /protein_end="304"
                     /protein_start="61"
                     /score="51.1"
                     /tool="antismash"
                     /translation="RSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNE
                     MRCIEHLLQRQVDAIIVSTALPPEHPFYQRWANDPLPIIALDRALDREHFISVVGADQE
                     DALMLAQELRAFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVDYLYANSYEREA
                     AGVLFAQWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPSNLAIATFGDNELLDFLE
                     CPVLAVAQRHRDVAERVLELV"
     PFAM_domain     complement(6913..7059)
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00356.23"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3565_0132"
                     /evalue="1.40E-18"
                     /label="ctg1_3565"
                     /locus_tag="ctg1_3565"
                     /protein_end="50"
                     /protein_start="1"
                     /score="66.4"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREHN
                     YHPN"
     CDS             complement(7357..7851)
                     /locus_tag="ctg1_3566"
                     /transl_table=11
                     /translation="MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKR
                     CAEIFRGQIVDVTATLYTVQLAGTSDKLDAFLNAVREVAEIVEVARSGIVGVSRGDKIM
                     R"
     aSDomain        complement(7372..7845)
                     /aSDomain="TIGR00119"
                     /aSTool="tigrfam"
                     /description="acolac_sm: acetolactate synthase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3566_0037"
                     /evalue="4.00E-66"
                     /identifier="TIGR00119"
                     /label="ctg1_3566"
                     /locus_tag="ctg1_3566"
                     /protein_end="160"
                     /protein_start="2"
                     /score="219.8"
                     /tool="antismash"
                     /translation="RRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRM
                     TIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCA
                     EIFRGQIVDVTATLYTVQLAGTSDKLDAFLNAVREVAEIVEVARSGIVGVSRGD"
     PFAM_domain     complement(7375..7599)
                     /aSDomain="ALS_ss_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10369.11"
                     /description="Small subunit of acetolactate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3566_0135"
                     /evalue="2.30E-23"
                     /label="ctg1_3566"
                     /locus_tag="ctg1_3566"
                     /protein_end="159"
                     /protein_start="84"
                     /score="82.3"
                     /tool="antismash"
                     /translation="REIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTS
                     DKLDAFLNAVREVAEIVEVARSGIVGVSRG"
     PFAM_domain     complement(7645..7839)
                     /aSDomain="ACT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01842.27"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3566_0134"
                     /evalue="8.20E-15"
                     /label="ctg1_3566"
                     /locus_tag="ctg1_3566"
                     /protein_end="69"
                     /protein_start="4"
                     /score="54.4"
                     /tool="antismash"
                     /translation="ILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTI
                     QTVGDAKVLEQIEKQLHKLV"
     CDS             complement(7854..9629)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 583.1;
                     E-value: 9.9e-177)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3567"
                     /transl_table=11
                     /translation="MTSRYPMSKLSLEAKPMEMLSGAEMVVRSLIDQGVKHVFGYPGGA
                     VLDIYDALHTVGGIDHVLVRHEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIAT
                     AYMDSVPMVVLSGQVPSSLIGYDAFQECDMVGISRPVVKHSFLVKRTEDIPTVLKKAFY
                     LASTGRPGPVVIDLPKDIVGPAVKMPYAYPDQVSLRSYNPTVQGHRGQIKRALQTILAA
                     KKPIMYVGGGAINSACHEELLVLAEKLNLPVTSSLMGLGSFPGTHRQSVGMLGMHGTFE
                     ANMAMHNTDLIFAVGVRFDDRTTNNLAKYCPNATVVHIDIDPTSISKTVNADIPIVGDA
                     KQVLVQMLELLSQIDCTQDCDSLRDWWQSIEQWRARNCLSYNKDSGKIKPQAVIETLHR
                     LTSGDAYVTSDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKLALPDETV
                     VCVTGDGSIQMNIQELSTALQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMDSL
                     PDFVKLAEAYGHIGVSIRTPDELESKLADALTQLSETKRLVFVDVTVDETEHVYPMQIR
                     GGGMDEMWLSKTERT"
     aSDomain        complement(7872..9572)
                     /aSDomain="TIGR00118"
                     /aSTool="tigrfam"
                     /description="acolac_lg: acetolactate synthase, large
                     subunit, biosynthetic type"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3567_0038"
                     /evalue="7.90E-279"
                     /identifier="TIGR00118"
                     /label="ctg1_3567"
                     /locus_tag="ctg1_3567"
                     /protein_end="586"
                     /protein_start="19"
                     /score="923.7"
                     /tool="antismash"
                     /translation="LSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLV
                     RHEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSL
                     IGYDAFQECDMVGISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIV
                     GPAVKMPYAYPDQVSLRSYNPTVQGHRGQIKRALQTILAAKKPIMYVGGGAINSACHEE
                     LLVLAEKLNLPVTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFD
                     DRTTNNLAKYCPNATVVHIDIDPTSISKTVNADIPIVGDAKQVLVQMLELLSQIDCTQD
                     CDSLRDWWQSIEQWRARNCLSYNKDSGKIKPQAVIETLHRLTSGDAYVTSDVGQHQMFA
                     ALYYPFDKPRRWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTA
                     LQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRT
                     PDELESKLADALTQLSETKRLVFVDVTVDETEHVYPMQIRGGGMDEMWLS"
     PFAM_domain     complement(7944..8402)
                     /aSDomain="TPP_enzyme_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02775.23"
                     /description="Thiamine pyrophosphate enzyme, C-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3567_0138"
                     /evalue="6.00E-50"
                     /label="ctg1_3567"
                     /locus_tag="ctg1_3567"
                     /protein_end="562"
                     /protein_start="409"
                     /score="169.1"
                     /tool="antismash"
                     /translation="DVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKLALP
                     DETVVCVTGDGSIQMNIQELSTALQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSY
                     MDSLPDFVKLAEAYGHIGVSIRTPDELESKLADALTQLSETKRLVFVDV"
     PFAM_domain     complement(8592..8996)
                     /aSDomain="TPP_enzyme_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00205.24"
                     /description="Thiamine pyrophosphate enzyme, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3567_0137"
                     /evalue="1.10E-47"
                     /label="ctg1_3567"
                     /locus_tag="ctg1_3567"
                     /protein_end="346"
                     /protein_start="211"
                     /score="161.4"
                     /tool="antismash"
                     /translation="IKRALQTILAAKKPIMYVGGGAINSACHEELLVLAEKLNLPVTSS
                     LMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDRTTNNLAKYCPNAT
                     VVHIDIDPTSISKTVNADIPIVGDAKQVLVQ"
     PFAM_domain     complement(9072..9569)
                     /aSDomain="TPP_enzyme_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02776.20"
                     /description="Thiamine pyrophosphate enzyme, N-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3567_0136"
                     /evalue="7.00E-58"
                     /label="ctg1_3567"
                     /locus_tag="ctg1_3567"
                     /protein_end="186"
                     /protein_start="20"
                     /score="195.1"
                     /tool="antismash"
                     /translation="SGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVR
                     HEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLI
                     GYDAFQECDMVGISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVG
                     PAV"
     CDS             complement(10001..11953)
                     /NRPS_PKS="Domain: AMP-binding (65-519). E-value: 2.3e-89.
                     Score: 291.6. Matches aSDomain:
                     nrpspksdomains_ctg1_3568_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     273.8; E-value: 3.9e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3568"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-90, bitscore:
                     301.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNQYPIDFKVRDGAKRKAPDKLVQSPDLDKRKPLHSSNLKDGEY
                     KASGDVMTHTLEQYHLVRRLRQQISHRADQIALREWSPEGEQQLSWQQVDTHVTQISAA
                     LLSLGVAIQERIGIFANNSMTWSLADLAILQLRGVSVPLYATNTSAQAAYVLNDADVRI
                     LFVGGQTQFDVAATLKPLCPQLAQIIVLDPTVDLRGCEYAQHLADFEQQPDAVQQHLLT
                     ARIDSCDLNDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTAEDVSLSFLPL
                     SHVFERAWSFYVMHTGAQNVYISNTDWVRPAMLAVKPTVMCAVPRFYEKVFSAINDKVA
                     LAKWHRRMLFRWAVGCGERQFQSLQRGQKLSLLSGQMYKLADRLVLSKLRGVLGGRVRF
                     LPAAGARLDDNIILFFQAIGINIKYGYGMTETCATVSCWEEQDFRFGSIGKPLPGIDVR
                     LGAENEIQVRGPIVMRGYFNKPQETAESFTEDGWLKTGDAGALDAQGNLFITERLKDLM
                     KTSGGKYIAPQMIEGTLGQDRFIEQVAIIADTRKFVSALIVPCFESLEEYARSINLKYH
                     DRLELLRHSHIVSLFEQRLKDMQKELALFEQVKRFTLLPQAFTMETGELTPTMKLRRKI
                     ILQRYQNEIDSMYRD"
     aSDomain        complement(10397..11758)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3568_AMP-binding.1"
                     /evalue="2.30E-89"
                     /label="ctg1_3568_AMP-binding.1"
                     /locus_tag="ctg1_3568"
                     /protein_end="519"
                     /protein_start="65"
                     /score="291.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RQQISHRADQIALREWSPEGEQQLSWQQVDTHVTQISAALLSLGV
                     AIQERIGIFANNSMTWSLADLAILQLRGVSVPLYATNTSAQAAYVLNDADVRILFVGGQ
                     TQFDVAATLKPLCPQLAQIIVLDPTVDLRGCEYAQHLADFEQQPDAVQQHLLTARIDSC
                     DLNDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTAEDVSLSFLPLSHVFER
                     AWSFYVMHTGAQNVYISNTDWVRPAMLAVKPTVMCAVPRFYEKVFSAINDKVALAKWHR
                     RMLFRWAVGCGERQFQSLQRGQKLSLLSGQMYKLADRLVLSKLRGVLGGRVRFLPAAGA
                     RLDDNIILFFQAIGINIKYGYGMTETCATVSCWEEQDFRFGSIGKPLPGIDVRLGAENE
                     IQVRGPIVMRGYFNKPQETAESFTEDGWLKTGDAGALDAQGNLFITERLKDLMKT"
     PFAM_domain     complement(10397..11758)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3568_0139"
                     /evalue="2.60E-93"
                     /label="ctg1_3568"
                     /locus_tag="ctg1_3568"
                     /protein_end="519"
                     /protein_start="65"
                     /score="313.0"
                     /tool="antismash"
                     /translation="RQQISHRADQIALREWSPEGEQQLSWQQVDTHVTQISAALLSLGV
                     AIQERIGIFANNSMTWSLADLAILQLRGVSVPLYATNTSAQAAYVLNDADVRILFVGGQ
                     TQFDVAATLKPLCPQLAQIIVLDPTVDLRGCEYAQHLADFEQQPDAVQQHLLTARIDSC
                     DLNDLFTLIYTSGTTGEPKGVMLDYRNMAAQLYLHDQRLTLTAEDVSLSFLPLSHVFER
                     AWSFYVMHTGAQNVYISNTDWVRPAMLAVKPTVMCAVPRFYEKVFSAINDKVALAKWHR
                     RMLFRWAVGCGERQFQSLQRGQKLSLLSGQMYKLADRLVLSKLRGVLGGRVRFLPAAGA
                     RLDDNIILFFQAIGINIKYGYGMTETCATVSCWEEQDFRFGSIGKPLPGIDVRLGAENE
                     IQVRGPIVMRGYFNKPQETAESFTEDGWLKTGDAGALDAQGNLFITERLKDLMKT"
     CDS_motif       complement(10493..10564)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_3568_0002"
                     /evalue="3.60E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_3568"
                     /protein_end="487"
                     /protein_start="463"
                     /score="25.8"
                     /tool="antismash"
                     /translation="EIQVRGPIVMRGYFNKPQETAESF"
     CDS_motif       complement(11201..11248)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_3568_0001"
                     /evalue="1.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_3568"
                     /protein_end="251"
                     /protein_start="235"
                     /score="24.2"
                     /tool="antismash"
                     /translation="LIYTSGTTGEPKGVML"
     CDS             complement(12247..13203)
                     /gene_functions="regulatory (smcogs) SMCOG1125:LysR family
                     transcriptional regulator (Score: 239.7; E-value: 7.5e-73)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3569"
                     /transl_table=11
                     /translation="MFEHNLVADDQVTKKEGSDVHLRSVDLNLLTVFDAVMQMHNVTRA
                     AQSLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTSRARQLFGPVRQALQLVQNELP
                     GAGFEAKKSKRIFKLSVCSPLDIRLTAQIIQCIKQLAPNVQIMIKSYLNDNIEHQLRYQ
                     ETEFVIGYTKFERPDFHYLSISNDESVLVVSKDHPRIGNSITQEQLLSELHAVVSLDKV
                     GSFSGHYYESEVSAQTIVYESTDMNSVLNIVSQTCFVAIAPRWLAQKYSDALNLKLISL
                     PWKNTNRPCYLTWHESTDRDKGHQWMKELLSQLTIPA"
     PFAM_domain     complement(12268..12831)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3569_0141"
                     /evalue="2.60E-17"
                     /label="ctg1_3569"
                     /locus_tag="ctg1_3569"
                     /protein_end="312"
                     /protein_start="124"
                     /score="63.0"
                     /tool="antismash"
                     /translation="LDIRLTAQIIQCIKQLAPNVQIMIKSYLNDNIEHQLRYQETEFVI
                     GYTKFERPDFHYLSISNDESVLVVSKDHPRIGNSITQEQLLSELHAVVSLDKVGSFSGH
                     YYESEVSAQTIVYESTDMNSVLNIVSQTCFVAIAPRWLAQKYSDALNLKLISLPWKNTN
                     RPCYLTWHESTDRDKGHQWMKELLS"
     PFAM_domain     complement(12949..13125)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3569_0140"
                     /evalue="3.60E-17"
                     /label="ctg1_3569"
                     /locus_tag="ctg1_3569"
                     /protein_end="85"
                     /protein_start="26"
                     /score="62.1"
                     /tool="antismash"
                     /translation="LNLLTVFDAVMQMHNVTRAAQSLGMSQPAVSNAVARLKVMFNDEL
                     FVRYGRGIQPTSRA"
     CDS             13836..13988
                     /locus_tag="ctg1_3570"
                     /transl_table=11
                     /translation="MWHTKTDVFLSRQMIYGPKYQRSTIIHIMKIMPNKTKSSVSIFRL
                     KTLYI"
     CDS             14309..15871
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 426.7;
                     E-value: 2e-129)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3571"
                     /sec_met_domain="HMGL-like (E-value: 1.5e-106, bitscore:
                     353.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEV
                     GFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATST
                     LHIESKLKRSFDDVLAMAVHSVKRARNYTNDVEFSCEDAGRTPIDNLCRIVEAAINAGA
                     TTINIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGA
                     RQVEGTINGLGERAGNCSLEEVIMAIKVREKMLGVHTNINHQEIYRTSQLVSKLCNMPI
                     PANKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPQSIGLKEVQLNLTSRSGRAAVKHR
                     MEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHYRLDYFSVQ
                     SGSSVMATASVKLVCGEDIKSEAATGNGPVDAVYQAINRITGYEIELVKYQLSANGQGK
                     DALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVDIEKQRLQQNNQ
                     EMV"
     PFAM_domain     14318..15127
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3571_0142"
                     /evalue="5.20E-107"
                     /label="ctg1_3571"
                     /locus_tag="ctg1_3571"
                     /protein_end="273"
                     /protein_start="3"
                     /score="357.4"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFP
                     VSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHI
                     ESKLKRSFDDVLAMAVHSVKRARNYTNDVEFSCEDAGRTPIDNLCRIVEAAINAGATTI
                     NIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGLGERAGNCSLEEVIMAIKVREKMLGVHTNINHQEIYRTSQLV"
     aSDomain        14318..15799
                     /aSDomain="TIGR00973"
                     /aSTool="tigrfam"
                     /description="leuA_bact: 2-isopropylmalate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3571_0039"
                     /evalue="2.00E-251"
                     /identifier="TIGR00973"
                     /label="ctg1_3571"
                     /locus_tag="ctg1_3571"
                     /protein_end="497"
                     /protein_start="3"
                     /score="832.6"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFP
                     VSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHI
                     ESKLKRSFDDVLAMAVHSVKRARNYTNDVEFSCEDAGRTPIDNLCRIVEAAINAGATTI
                     NIPDTVGYTTPYQFGGIITDLYERVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGLGERAGNCSLEEVIMAIKVREKMLGVHTNINHQEIYRTSQLVSKLCNMPIPAN
                     KAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPQSIGLKEVQLNLTSRSGRAAVKHRMEE
                     MGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHYRLDYFSVQSGS
                     SVMATASVKLVCGEDIKSEAATGNGPVDAVYQAINRITGYEIELVKYQLSANGQGKDAL
                     GQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLN"
     PFAM_domain     15413..15805
                     /aSDomain="LeuA_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08502.12"
                     /description="LeuA allosteric (dimerisation) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3571_0143"
                     /evalue="6.70E-37"
                     /label="ctg1_3571"
                     /locus_tag="ctg1_3571"
                     /protein_end="499"
                     /protein_start="368"
                     /score="126.4"
                     /tool="antismash"
                     /translation="QVFDYDLEALAFINKQQEEPEHYRLDYFSVQSGSSVMATASVKLV
                     CGEDIKSEAATGNGPVDAVYQAINRITGYEIELVKYQLSANGQGKDALGQVDIVVDHKG
                     RRFHGVGLATDIVESSAKALVHVLNNI"
     CDS             15874..16965
                     /locus_tag="ctg1_3572"
                     /transl_table=11
                     /translation="MTKTYHIAVLPGDGIGPEVMAQANKVLDAVRQRFGIKISTSAYDV
                     GGAAIDRHGSPLPAATVSGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKL
                     FSNLRPARLYQGLEDFCPLRSDIAAKGFDILCVRELTGGIYFGQPKGREGQGQHERAFD
                     TEVYHRFEIERIARIAFESARKRRGKVTSIDKANVLQSSILWREVVTAIAADYPDVALS
                     HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYE
                     PAGGSAPDIAGKNIANPIAQILSLTLLLRFSLGKDDAADAIERAINQALEQGYRTADLA
                     GEGKAIGTNEMGDVIAKFVMEGV"
     aSDomain        15889..16935
                     /aSDomain="TIGR00169"
                     /aSTool="tigrfam"
                     /description="leuB: 3-isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3572_0040"
                     /evalue="8.70E-167"
                     /identifier="TIGR00169"
                     /label="ctg1_3572"
                     /locus_tag="ctg1_3572"
                     /protein_end="354"
                     /protein_start="5"
                     /score="552.4"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEVMAQANKVLDAVRQRFGIKISTSAYDVGGAAI
                     DRHGSPLPAATVSGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLR
                     PARLYQGLEDFCPLRSDIAAKGFDILCVRELTGGIYFGQPKGREGQGQHERAFDTEVYH
                     RFEIERIARIAFESARKRRGKVTSIDKANVLQSSILWREVVTAIAADYPDVALSHMYID
                     NATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSLTLLLRFSLGKDDAADAIERAINQALEQGYRTADLAGEGKA
                     IGTNEMGDV"
     PFAM_domain     15889..16938
                     /aSDomain="Iso_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00180.22"
                     /description="Isocitrate/isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3572_0144"
                     /evalue="1.10E-137"
                     /label="ctg1_3572"
                     /locus_tag="ctg1_3572"
                     /protein_end="355"
                     /protein_start="5"
                     /score="459.0"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEVMAQANKVLDAVRQRFGIKISTSAYDVGGAAI
                     DRHGSPLPAATVSGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLR
                     PARLYQGLEDFCPLRSDIAAKGFDILCVRELTGGIYFGQPKGREGQGQHERAFDTEVYH
                     RFEIERIARIAFESARKRRGKVTSIDKANVLQSSILWREVVTAIAADYPDVALSHMYID
                     NATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSLTLLLRFSLGKDDAADAIERAINQALEQGYRTADLAGEGKA
                     IGTNEMGDVI"
     CDS             16967..18397
                     /locus_tag="ctg1_3573"
                     /transl_table=11
                     /translation="MGKTSYQNKTLYQKLYDAHIVYEAPNETPLLYIDRHLVHEVTSPQ
                     AFDGLRAMGRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLY
                     DLNHPFQGIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQT
                     LKQGRAKTMKIEVNGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGR
                     MTLCNMAIEMGAKAGLVAPDDTTFDYLKGRQFAPTGEQWEQGVAYWRTLKSDADAKFDT
                     IVTLDAADIAPQVTWGTNPGQVIAVNDMIPAPESFSDPVERASAEKALAYMDLRPGIKL
                     TEVAIDKVFIGSCTNSRIEDLRAAAAVAQGRKVATGVQAIVVPGSGPVKAQAEAEGLDK
                     IFIEAGFEWRLPGCSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAA
                     AAVSGHFADVRDLEAATH"
     aSDomain        16988..18379
                     /aSDomain="TIGR00170"
                     /aSTool="tigrfam"
                     /description="leuC: 3-isopropylmalate dehydratase, large
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3573_0041"
                     /evalue="1.60E-267"
                     /identifier="TIGR00170"
                     /label="ctg1_3573"
                     /locus_tag="ctg1_3573"
                     /protein_end="471"
                     /protein_start="7"
                     /score="885.5"
                     /tool="antismash"
                     /translation="NKTLYQKLYDAHIVYEAPNETPLLYIDRHLVHEVTSPQAFDGLRA
                     MGRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLYDLNHPFQ
                     GIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAK
                     TMKIEVNGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMA
                     IEMGAKAGLVAPDDTTFDYLKGRQFAPTGEQWEQGVAYWRTLKSDADAKFDTIVTLDAA
                     DIAPQVTWGTNPGQVIAVNDMIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDK
                     VFIGSCTNSRIEDLRAAAAVAQGRKVATGVQAIVVPGSGPVKAQAEAEGLDKIFIEAGF
                     EWRLPGCSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSGHF
                     ADVRDL"
     PFAM_domain     17006..18355
                     /aSDomain="Aconitase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00330.22"
                     /description="Aconitase family (aconitate hydratase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3573_0145"
                     /evalue="7.60E-164"
                     /label="ctg1_3573"
                     /locus_tag="ctg1_3573"
                     /protein_end="463"
                     /protein_start="13"
                     /score="546.2"
                     /tool="antismash"
                     /translation="KLYDAHIVYEAPNETPLLYIDRHLVHEVTSPQAFDGLRAMGRPVR
                     QPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLYDLNHPFQGIVHVI
                     GPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMKIEV
                     NGTVGAGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMAIEMGAK
                     AGLVAPDDTTFDYLKGRQFAPTGEQWEQGVAYWRTLKSDADAKFDTIVTLDAADIAPQV
                     TWGTNPGQVIAVNDMIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDKVFIGSC
                     TNSRIEDLRAAAAVAQGRKVATGVQAIVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPG
                     CSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSG"
     PFAM_domain     18412..18786
                     /aSDomain="Aconitase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00694.21"
                     /description="Aconitase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3574_0146"
                     /evalue="6.10E-40"
                     /label="ctg1_3574"
                     /locus_tag="ctg1_3574"
                     /protein_end="125"
                     /protein_start="0"
                     /score="136.7"
                     /tool="antismash"
                     /translation="MAKFTQHTGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFND
                     WRFLDDAGQVPNPEFVLNQPRYLGATILLARENFGCGSSREHAPWALTDFGFKVVIAPS
                     FADIFYGNSFNNQLLPVTLSE"
     aSDomain        18412..18975
                     /aSDomain="TIGR00171"
                     /aSTool="tigrfam"
                     /description="leuD: 3-isopropylmalate dehydratase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3574_0042"
                     /evalue="3.80E-97"
                     /identifier="TIGR00171"
                     /label="ctg1_3574"
                     /locus_tag="ctg1_3574"
                     /protein_end="188"
                     /protein_start="0"
                     /score="321.6"
                     /tool="antismash"
                     /translation="MAKFTQHTGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFND
                     WRFLDDAGQVPNPEFVLNQPRYLGATILLARENFGCGSSREHAPWALTDFGFKVVIAPS
                     FADIFYGNSFNNQLLPVTLSEADIDTLFQLVNDNEGIEFIVDLEEQTVKAGGNSYSFEI
                     DSFRRHCMINGLDSIGLTLQHESNI"
     CDS             18412..19014
                     /locus_tag="ctg1_3574"
                     /transl_table=11
                     /translation="MAKFTQHTGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFND
                     WRFLDDAGQVPNPEFVLNQPRYLGATILLARENFGCGSSREHAPWALTDFGFKVVIAPS
                     FADIFYGNSFNNQLLPVTLSEADIDTLFQLVNDNEGIEFIVDLEEQTVKAGGNSYSFEI
                     DSFRRHCMINGLDSIGLTLQHESNISAYEKQQPAFLR"
     CDS             19313..19411
                     /locus_tag="ctg1_3575"
                     /transl_table=11
                     /translation="MTRIALRYEARISGDSRAWFNIDYRLANDFPR"
     aSDomain        19346..19405
                     /aSDomain="TIGR02616"
                     /aSTool="tigrfam"
                     /description="tnaC_leader: tryptophanase leader peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3575_0043"
                     /evalue="2.10E-08"
                     /identifier="TIGR02616"
                     /label="ctg1_3575"
                     /locus_tag="ctg1_3575"
                     /protein_end="31"
                     /protein_start="11"
                     /score="31.9"
                     /tool="antismash"
                     /translation="ISGDSRAWFNIDYRLANDFP"
     CDS             19609..21009
                     /NRPS_PKS="Domain: Beta_elim_lyase (45-431). E-value:
                     8e-100. Score: 325.6. Matches aSDomain:
                     nrpspksdomains_ctg1_3576_Beta_elim_lyase.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg1_3576"
                     /transl_table=11
                     /translation="MKRIPEPFRIKMVENIRMTNREDREKALIEAGYNPFLLPSEDVYI
                     DLLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGYPFTIPTHQGRGAEQ
                     ILFPCLIAKKQKAGGGKKPVFISNFHFDTTAAHVEMNGAKAINVVTPKAFDTVAYYDWK
                     GDFDLDQLKATIAEHGAENVVSIITTVTCNSSGGQPISMSNMREVYRIAQQHNIPVVID
                     SARFCENAWFIKQREPGYADKSVKEIILEMYQYGDMLTMSAKKDPMVNIGGLCCFRTDE
                     DLFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLKYRIGQVEYLGDRLRA
                     GGIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNELYLEAGIRSVEIGSLLLGRDP
                     ETGKQKPSPLELLRLTIPRRVYTNDHMDYIADALISLKSRAHDIKGLTFTYEPPVLRHF
                     VARLKPVE"
     aSDomain        19612..21003
                     /aSDomain="TIGR02617"
                     /aSTool="tigrfam"
                     /description="tnaA_trp_ase: tryptophanase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3576_0044"
                     /evalue="3.10E-261"
                     /identifier="TIGR02617"
                     /label="ctg1_3576"
                     /locus_tag="ctg1_3576"
                     /protein_end="465"
                     /protein_start="1"
                     /score="865.2"
                     /tool="antismash"
                     /translation="KRIPEPFRIKMVENIRMTNREDREKALIEAGYNPFLLPSEDVYID
                     LLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGYPFTIPTHQGRGAEQI
                     LFPCLIAKKQKAGGGKKPVFISNFHFDTTAAHVEMNGAKAINVVTPKAFDTVAYYDWKG
                     DFDLDQLKATIAEHGAENVVSIITTVTCNSSGGQPISMSNMREVYRIAQQHNIPVVIDS
                     ARFCENAWFIKQREPGYADKSVKEIILEMYQYGDMLTMSAKKDPMVNIGGLCCFRTDED
                     LFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLKYRIGQVEYLGDRLRAG
                     GIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNELYLEAGIRSVEIGSLLLGRDPE
                     TGKQKPSPLELLRLTIPRRVYTNDHMDYIADALISLKSRAHDIKGLTFTYEPPVLRHFV
                     ARLKPV"
     aSDomain        19744..20901
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3576_Beta_elim_lyase.1"
                     /evalue="8.00E-100"
                     /label="ctg1_3576_Beta_elim_lyase.1"
                     /locus_tag="ctg1_3576"
                     /protein_end="431"
                     /protein_start="45"
                     /score="325.6"
                     /tool="antismash"
                     /translation="DLLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGY
                     PFTIPTHQGRGAEQILFPCLIAKKQKAGGGKKPVFISNFHFDTTAAHVEMNGAKAINVV
                     TPKAFDTVAYYDWKGDFDLDQLKATIAEHGAENVVSIITTVTCNSSGGQPISMSNMREV
                     YRIAQQHNIPVVIDSARFCENAWFIKQREPGYADKSVKEIILEMYQYGDMLTMSAKKDP
                     MVNIGGLCCFRTDEDLFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLKY
                     RIGQVEYLGDRLRAGGIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNELYLEAGI
                     RSVEIGSLLLGRDPETGKQKPSPLELLRLTIPRRVYTNDHMDYIAD"
     PFAM_domain     19744..20901
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01212.23"
                     /description="Beta-eliminating lyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3576_0147"
                     /evalue="2.80E-97"
                     /label="ctg1_3576"
                     /locus_tag="ctg1_3576"
                     /protein_end="431"
                     /protein_start="45"
                     /score="325.6"
                     /tool="antismash"
                     /translation="DLLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGY
                     PFTIPTHQGRGAEQILFPCLIAKKQKAGGGKKPVFISNFHFDTTAAHVEMNGAKAINVV
                     TPKAFDTVAYYDWKGDFDLDQLKATIAEHGAENVVSIITTVTCNSSGGQPISMSNMREV
                     YRIAQQHNIPVVIDSARFCENAWFIKQREPGYADKSVKEIILEMYQYGDMLTMSAKKDP
                     MVNIGGLCCFRTDEDLFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLKY
                     RIGQVEYLGDRLRAGGIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNELYLEAGI
                     RSVEIGSLLLGRDPETGKQKPSPLELLRLTIPRRVYTNDHMDYIAD"
     CDS             21120..22382
                     /locus_tag="ctg1_3577"
                     /transl_table=11
                     /translation="MAQTTLEDQVAARKIKNPSLLGGAMIIAGTIVGAGMFSLPVVMSG
                     IWFYWSIAVLVFTWFCMLHSGLMILEANLNYHTGASFDTITKDLLGNGWNVINGLTVAF
                     VLYILTYAYISASGSVIQHTLRGMGIDFPARLGGLFFALFVAFIVWLSTTAVSRMTTIV
                     LGAKILTFFMTFGGLLGHVEPVKLFNLSEANPSYLPYLLMTLPFCLASFGYHGNVPSLM
                     KYYGKNPHRIRNCLLIGTLLALTLYIIWLVGTMGNIPRPQFREIASQGGNIDVLVSALG
                     GILQSSSMDLLLTVFSNFAVASSFLGVTLGLFDYLADLFKFDDSRLGRGKTAVITFLPP
                     ILGGLIYPDGFIYAIGYAGLAATVWAAIVPALLARASRKRFGSPLYRVWGGTPLIIVIL
                     LFGAVNAIAHILSSLNLLPIY"
     PFAM_domain     21165..22346
                     /aSDomain="Trp_Tyr_perm"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03222.15"
                     /description="Tryptophan/tyrosine permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3577_0148"
                     /evalue="9.30E-152"
                     /label="ctg1_3577"
                     /locus_tag="ctg1_3577"
                     /protein_end="409"
                     /protein_start="15"
                     /score="505.7"
                     /tool="antismash"
                     /translation="KNPSLLGGAMIIAGTIVGAGMFSLPVVMSGIWFYWSIAVLVFTWF
                     CMLHSGLMILEANLNYHTGASFDTITKDLLGNGWNVINGLTVAFVLYILTYAYISASGS
                     VIQHTLRGMGIDFPARLGGLFFALFVAFIVWLSTTAVSRMTTIVLGAKILTFFMTFGGL
                     LGHVEPVKLFNLSEANPSYLPYLLMTLPFCLASFGYHGNVPSLMKYYGKNPHRIRNCLL
                     IGTLLALTLYIIWLVGTMGNIPRPQFREIASQGGNIDVLVSALGGILQSSSMDLLLTVF
                     SNFAVASSFLGVTLGLFDYLADLFKFDDSRLGRGKTAVITFLPPILGGLIYPDGFIYAI
                     GYAGLAATVWAAIVPALLARASRKRFGSPLYRVWGGTPLIIVILLFGAVNAIAH"
     aSDomain        21183..22325
                     /aSDomain="TIGR00837"
                     /aSTool="tigrfam"
                     /description="araaP: aromatic amino acid transport protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3577_0045"
                     /evalue="3.20E-157"
                     /identifier="TIGR00837"
                     /label="ctg1_3577"
                     /locus_tag="ctg1_3577"
                     /protein_end="402"
                     /protein_start="21"
                     /score="521.7"
                     /tool="antismash"
                     /translation="GGAMIIAGTIVGAGMFSLPVVMSGIWFYWSIAVLVFTWFCMLHSG
                     LMILEANLNYHTGASFDTITKDLLGNGWNVINGLTVAFVLYILTYAYISASGSVIQHTL
                     RGMGIDFPARLGGLFFALFVAFIVWLSTTAVSRMTTIVLGAKILTFFMTFGGLLGHVEP
                     VKLFNLSEANPSYLPYLLMTLPFCLASFGYHGNVPSLMKYYGKNPHRIRNCLLIGTLLA
                     LTLYIIWLVGTMGNIPRPQFREIASQGGNIDVLVSALGGILQSSSMDLLLTVFSNFAVA
                     SSFLGVTLGLFDYLADLFKFDDSRLGRGKTAVITFLPPILGGLIYPDGFIYAIGYAGLA
                     ATVWAAIVPALLARASRKRFGSPLYRVWGGTPLIIVILLFG"
     CDS             complement(22410..23591)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 76.2; E-value: 3.1e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3578"
                     /transl_table=11
                     /translation="MKSALTFSRRINPVFLAFFVVAFLSGIAGALQAPTLSLFLSTEVK
                     VRPLWVGLFYTVNAIAGITVSFVLAKRSDLRGDRRKLIMVCYLMAVGNCLLFAFNRDYL
                     TLITAGVLLAAVANTAMPQIFALAREYADSSAREVVMFSSIMRAQLSLAWVIGPPLSFM
                     LALNYGFTLMFSIAAGIFVLSALVVWFILPSVQRAEPEVDASAVVQGSLFADKDVLLLF
                     IASMLMWTCNTMYIIDMPLYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGK
                     RKIMLFAVLAGVLFYTGLVLFKFKTALMLLQIFNAIFIGIVAGIGMLYFQDLMPGRAGA
                     ATTLFTNSISTGVILAGVLQGVLTETWGHNSVYVVAMGLAILALIICARVREA"
     aSDomain        complement(22419..23543)
                     /aSDomain="TIGR00899"
                     /aSTool="tigrfam"
                     /description="2A0120: sugar efflux transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3578_0046"
                     /evalue="1.40E-159"
                     /identifier="TIGR00899"
                     /label="ctg1_3578"
                     /locus_tag="ctg1_3578"
                     /protein_end="391"
                     /protein_start="16"
                     /score="529.2"
                     /tool="antismash"
                     /translation="AFFVVAFLSGIAGALQAPTLSLFLSTEVKVRPLWVGLFYTVNAIA
                     GITVSFVLAKRSDLRGDRRKLIMVCYLMAVGNCLLFAFNRDYLTLITAGVLLAAVANTA
                     MPQIFALAREYADSSAREVVMFSSIMRAQLSLAWVIGPPLSFMLALNYGFTLMFSIAAG
                     IFVLSALVVWFILPSVQRAEPEVDASAVVQGSLFADKDVLLLFIASMLMWTCNTMYIID
                     MPLYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGKRKIMLFAVLAGVLFYT
                     GLVLFKFKTALMLLQIFNAIFIGIVAGIGMLYFQDLMPGRAGAATTLFTNSISTGVILA
                     GVLQGVLTETWGHNSVYVVAMGLAILALIICARVR"
     PFAM_domain     complement(22557..23537)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3578_0149"
                     /evalue="3.90E-32"
                     /label="ctg1_3578"
                     /locus_tag="ctg1_3578"
                     /protein_end="345"
                     /protein_start="18"
                     /score="111.6"
                     /tool="antismash"
                     /translation="FVVAFLSGIAGALQAPTLSLFLSTEVKVRPLWVGLFYTVNAIAGI
                     TVSFVLAKRSDLRGDRRKLIMVCYLMAVGNCLLFAFNRDYLTLITAGVLLAAVANTAMP
                     QIFALAREYADSSAREVVMFSSIMRAQLSLAWVIGPPLSFMLALNYGFTLMFSIAAGIF
                     VLSALVVWFILPSVQRAEPEVDASAVVQGSLFADKDVLLLFIASMLMWTCNTMYIIDMP
                     LYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGKRKIMLFAVLAGVLFYTGL
                     VLFKFKTALMLLQIFNAIFIGIVAGIGMLYFQDLMPGRAGAATTLF"
ORIGIN
        1 gttgctaata attgtgctag cggataaccc agtgaaagga gtgttgacag tgccaccagc
       61 agattactga cgttaaacgc ccccatcaaa cggctttcta atttgccttc gccccagctt
      121 gagtcaaaag cgatgctggc accgttatcg tgataatgaa cgttattcgc cgataaccac
      181 gggccattcc agcccgtagg aacctggcct tccatgctga cagcgactgc ttgcggcaac
      241 tgccctaacc agcggcgacc gacttcgtca tcagcattga taattttgtg ttcggattga
      301 tgggtggaga acagcaacca ttttgccgcc tcataactcg ccatattgcc gtgataatcc
      361 agatgatcgc ggcttaagtt agtgaacacg gcggcagcaa acggcaatgc agctacgcgg
      421 ttttgaatca aaccgtggga agaaacttcc atcgccgcaa aagtagcccc ttgatcaacc
      481 aaattgcgca gtaaatgctg gatatcaacc gctgaaccgg tggtattttc cgtcgggatc
      541 acttgcccta acaaaccatt gccaaccgta cccattaccg cgctggtttc ccccagtgcc
      601 tggctccatt gtgccaacag ttgggtggtg gtggttttgc cgttggtccc cgtcacaccg
      661 accaaacgta atgctgcacc cggctggtgg tagaattgcc ccgccagctt ggataaatgt
      721 tgattcaaat tacgcaaata aataacagga acaccatgca tctctaccac actggcatcc
      781 ggtgccacgc catcggcttc ggctatcacg gctgcaacac cttgtgcgat agcttgcggg
      841 atatagcgac gcccgtccgt ctggtggccg acaatggcga caaacaaatc cccggcagcg
      901 gcaacacggc tgtctaatgt catttcccgt agcgcacgct ccgggacgtc tagcccccaa
      961 ggagcgagta agtcgcgcaa gttacgatct gccacctgaa ccctcttttg tattaatcac
     1021 taattcgctt ttatcaccgg tgggtaacgc atctggctca atgttcatgg tacgcagaac
     1081 gccgcccatg atggcaccga acaccggtgc agagacggca ccaccgtaat atttccctgc
     1141 ctgcgggtca ttgatgacca caaccagagc aaatcgaggg ttactcgcgg gcgcaacgcc
     1201 ggcggtgtaa gcgaggtatc ggtccatata cttgccatcc gggccaacct tcttggcagt
     1261 accggtttta atggcaatac ggtagccttt aatggcggct ttcgtgcccc cgccgccagg
     1321 taatgccaca ctttccatca tatgcaccac ggtacgaacc agcggttcag ggaaaatgcg
     1381 ttcaccggcc actggcgggt caactttggt gatcgacagc gggcgataaa tccccatgct
     1441 gccgatggtt gcatagactc gcgctagttg taacggtgtt accattagcc cgtagccgaa
     1501 agagaaggtg gccctctcta tgtcagacca ccgttgtttt ttaggatata agccactgct
     1561 ttctccgacc aaccccaaat tggtcgcttt cccaaaccca aaccgtgagt aagtatctac
     1621 taacgctgag gatggcatcg ctaacgccag cttagaaaca ccgacgttac tcgacttctg
     1681 caagatcccg gtcacggaca gctctgcgta acgggccacg tctttaatct ggtgcccatt
     1741 aacaaagtac ggcaaggtat tcagcacgct gttttctttc acaacgccat gctgcaatgc
     1801 cgtcatcact accattggct tcactgtgga gccgggttca aaaatatcgg ttatcgcccg
     1861 gttacgcatc gcatctttcg gcgttccggt caggttattc gggttataag acgggctatt
     1921 cgccattgct aatacttcgc cggtactcac atctaccagc accgcagtgc ctgattctgc
     1981 tttgttgaat gccaccgcat tgttcaattc gcgatacacc agcgcctgta ggcgctcgtc
     2041 aacactcaac accaggttat gtgcggcctg actatcaaca gaagagatat cctcaatgac
     2101 acgaccatag cggtctttac gtaccgtacg ctcacctggt tgcccagtga gccaacggtc
     2161 aaaacttttc tcaacccctt caatgccttg gccatcaata ttggtgacac caataatgtg
     2221 tgccatcacc tgaccggccg gatagtagcg gcgtgattcc tgccgcagat agataccggg
     2281 gagtttcagt ttatggatat agtcgccaat cgcggggtta acctgacgcg ccagataaac
     2341 gaaacgccct ttaggattgg cattaatacg ggtcgccaat tgatccagtg ggatttccag
     2401 agcatccgat agcgctttcc agcgagtatc taacgtaata ccaccacgct cggtcagctc
     2461 tttcggatca gcccaaaccg cattgaccgg cacgcttacc gccaacgggc ggcctgagcg
     2521 gtcactgatc atgccacgag ccgtcggtac ttcctgcact cgcagcgagc gcatatcacc
     2581 ctcgcgcacc agtttgtcag gattaatcac ttgcaggtac gcggtacgta acatcaaacc
     2641 gaccaatgcc agcaaaatac agccgcacag caacgcaaaa cgccagctaa taaagctggc
     2701 ttgttcttcc tggcgcttta acttcccggg gcgcgctgct ttcatccgtt accttggcta
     2761 ctcaacgtca tggtggcgac taattccttt atttattgga aataacctat tgtttaacca
     2821 caatattttc ttgtgatgga tcaacatgtt gcattttcag tttgtcagtc gcgatacttt
     2881 caacacgact gtggtcaccc aacgcgttct cttccaaaat caggttacgc cactcgatat
     2941 ccagcgcatc ccgttccagc accaactgct cacgctctgc ggtcaacaag cgtgtacggt
     3001 gagcggtggt taccacgaaa acagcagaca ccaacaccgc gatcagtaaa attaacggga
     3061 tcttcgcatt gcggattaaa tcaccgctga tgaccccaac taaaccgtgg cgttcgttgc
     3121 ctatcactct ttaatcctct cggcaaaacg caataccgag cttcgtgccc gtgggttttc
     3181 cgccacctca gcatctggag gcatcatttt gccagccgat ttcaatgtgc gcccacccat
     3241 gctgcgcaac tgcgcttccg tcaatggcaa ccctgcagga acctgtgggc cacggctatg
     3301 atgacgaata aagtttttaa caatgcgatc ttcaagagag tggaagctaa tcactgacaa
     3361 acggcccgca ggggccagaa cttcaagtgc gccatcaagt gcgcgctcaa tctcttccaa
     3421 ttcactgttg atatagatac gaatagcctg gaagctacgg gtagcgggat gtttgtgctt
     3481 ttcgcggaat gggctggcgt tggcaatcaa atcagccagc tctttggtgc gagtcatcgg
     3541 ttgagtaagg ttgcgctcaa caatggcttt agccaggcgc ttggcaaaac gctcttcacc
     3601 aaaggttttt aacacccacg cgatatcgtc ggcgctggct ttcatcaacc actcagcagc
     3661 agataatcca cgggaggggt ccatacgcat atccaatggc ccgtcacgca tgaaagagaa
     3721 accacgttca gggtcatcca actggggtga tgaaacccct agatcgagca atacaccgtc
     3781 aatgcgacca actaaatcca gttctcgcac ataatgcgct aactcggaaa aaggaccgtg
     3841 tacgatagag aaacgtggat cagtaataga ttttgccgct tcgatagctt gtgggtcacg
     3901 gtcaattgca atcagacgcc cttctggccc aagctgggac agaatcagac gcgaatggcc
     3961 accacggcca aaagtgccgt caatatagat gccgttatcg cggatgttca ggccatttac
     4021 cgcctcatcc agcaatacgc ttgtatgctt gtagttgtta tctacaattt tgttgttatc
     4081 taccatgctt atagcgataa gtcctgtagc cgctcagaca agggttcctg agtggactgt
     4141 tctgcgtcga tgtcatcctt gacttgttga taccaggtct gttcatccca cagttcaaac
     4201 ttgttgaact gcccaaccag catcacttct ttattcagcc cggcatgctg tcgcaatgtt
     4261 cctgcgatca gtaagcgccc ggcaccatcc atctgacatt cactggcgtg ccctaacagc
     4321 aaacgctgga cccgacgctc agccggattc atgctcgaca gacgggataa tttttgttca
     4381 atgatttccc attcagggag tggataaagc aacaggcatg gttggtgaag gtctatggta
     4441 cagaccatct ggccttgcga ctcctcgttc agtaaatccc gataacgggt aggtacggca
     4501 agccgccctt tactgtcgag gttaaccatc gttgcaccac gaaacatgac tgagttaccc
     4561 cttcatgacc caattcgcca ctttacccca caaatcccca cattaaagag tttacggatg
     4621 gtatgaaaac cttgtcaagc cagagccgat gcgctttgac aatatttatg ggccattttt
     4681 gagatatatc tcgtagaagg ggctatttta gtggttgtaa tagaaattaa cgtcatgata
     4741 aacgggctat ttttccgcca ataattctag ctacttaaat aaataattaa ttgccgatta
     4801 attgtctcat tatttccttc tgcaaggaat gtctcatttt tagtatgaaa attgtacggt
     4861 ctaaaaataa acagcctgag tacaaaaccc gctaccgctg gcgtctccta aggaaaaaca
     4921 gcgatagtcg gcggcaaaac ccacagcagc acaataataa ccttggaaac aacgagtgtt
     4981 actggcgcga cattttactt caattaacca atggggatta atctattttg aaataaatta
     5041 ttggcgcata tttcttagca tcactgaaat atgaatgtct tcaggcagat aaatcttaaa
     5101 ttagaaattt aagtaaatta gtttctgttt cacaccttat ttaaaatttg agttacgttg
     5161 ccggcccttt cctcgtcaac atcaaaaaac acaaccacat gtttttaaag aaaaaataga
     5221 catcccgcca tttaaaaaac cacccaaagc tcaattcctc acagtacaaa gtataaaaac
     5281 cagacaaatg ttaaaaataa aaattttaag ctggttatat taataacgat agcactgtaa
     5341 actatataaa aagcaaaata gcaatataat cacctgcaat ttaaatgata agcaatgtat
     5401 aaatcctgct aaaaatctca tcaattggta ttttggcaga cttttccccc aagtagggag
     5461 ttaatgacaa tgttttcaac tgggtcccgc ctgcgtagtg ctgcagccga tacttttgcg
     5521 ctcgtggtgt attgttttgt catcggtatg ataattgaaa tcgtgatctc gggaatgacc
     5581 ttccagcagt cactctcttc ccgcctggtt tcaatacccg tcaatatcct tattgcctgg
     5641 ccttatggtg tgtatcggga tgcctttatc cgctttgcgc gccatcatgc cgataagcat
     5701 tcttgggcgc ggaatctggc agacttactg gcctatgtca gcttccagtc tccggtttat
     5761 gccataatct tgtggtcggt cggggctgat ttagaacaaa ttactacggc ggttaccagt
     5821 aacgcgttgg tttcaatggc gatgggtgtg gcttacggct actttctgga atactgccgc
     5881 cggttgttcc gcgtggcagg ctatgtttga gaatattcgt catctttcat aatgcaggtg
     5941 tgttggcgtc actactcggc ccaacagcgg cctcacctcg ttgaggccgc tgttggcttc
     6001 ctacaccatg aaatttattg ggtattaacc gccctaaccg gaatatttat tactcggtta
     6061 cttgcggctc aaactgcccc ggcggaataa attgcggcga atacgggtta accccggttt
     6121 cggtttatgc ggttcatcca gactggctaa taccagctcc agcacgcgct cggcaacatc
     6181 acggtggcgc tgtgccactg ccagtactgg gcactcaagg aagtccaaca gctcgttatc
     6241 accaaaagta gcaatcgcca gattactggg taaacgccca ctttgcttta aggtcacatc
     6301 cataacgccc tgtagtagct ggaatgaggt ggtaaatagc gcctgtggca ttgggtgggt
     6361 cttaagccac tgcgcaaaca gcacgccagc agcttcgcgc tcgtagctat tggcatacag
     6421 gtaatcgact ttacgtggat catctttcca cgcctcacgg aatcccatct cacgcaagaa
     6481 actgaccgag agttccggca gcgcgcctaa atacaatacc gactctgcgg ggaaggcacg
     6541 tagttcttgt gccagcatca gtgcatcttc ttgatccgcg ccgacgacgc taatgaaatg
     6601 ctcccgatca agcgcccgat ccaatgcaat gattggcaat ggatcattag cccagcgctg
     6661 gtaaaaaggg tgctcagggg gcaatgcggt agaaacgata atggcatcaa cctggcgctg
     6721 taacaggtgt tcgatacaac gcatctcatt atctggctga tcttcagaac aggcgatcaa
     6781 cagttgataa ccgcgctggc gcgcctggcg ttccagataa tttgcaatac gggtatagct
     6841 ggtattctca aggtccggga tcaccaaacc aatggaacgg gttctgcccg cgcgcaatcc
     6901 tgccgcaaca gcatttgggt gatagttatg ttccctgaca accgccataa ctttgtctac
     6961 tgttttgtcg ctgactcggt actgtttcgc tttgccatta atgacataac tggccgttgt
     7021 acgcgaaacg cccgcaagac gcgcgatttc atccagtttc acattaaccc cttataaacc
     7081 caataaagtg atgaaaggca tgatgtctgc cagagctaag tatcccagtg attctcaaaa
     7141 acgccgataa actgcggtgt cacaagctaa accacaagat ttatagacat agtttaacta
     7201 cggatatagc acactgtaga tctaaccgca gaactcactc ttgagcaacc gctttaaccg
     7261 ccatataacg ctatctcggt taaaaaataa gaaaaaaaag cccgacacac ctgccgagcc
     7321 tgattattgg agattagtca gtgttaataa gtttcattaa cgcataatct tgtcaccgcg
     7381 tgacacaccg acaatacctg agcgggcaac ttcgacaatt tctgccactt cccgcaccgc
     7441 attgaggaat gcatccagct tatcactggt gccagccagt tggacggtgt aaagcgtggc
     7501 ggtcacatcc acaatttgcc cacggaagat ttccgcacac cgtttcactt cttcacgccc
     7561 gtaaccactg gcctgcaact tcaccaacat gatctcacgc tcaacatgtg agccagaaac
     7621 caactcacta acacgcagta catcgaccag tttatgcagt tgtttttcta tctgctccag
     7681 aaccttagca tcgcccacgg tctgaatcgt catgcgggac agtgtcggat cgtcggtcgg
     7741 cgcgaccgtt aaactctcaa tgttgtaacc acgttgagaa aacaggccca caactcttga
     7801 gagcgcacct gattcgtttt ccagtagaac tgataaaatc cggcggcgca taattatgtc
     7861 ctctccgttt tgctaagcca catttcgtcc atgccaccac cacgaatctg catcgggtaa
     7921 acatgctccg tttcatcaac cgtcacatcc acaaatacca aacgcttggt ctcggataat
     7981 tgtgtcaggg catcagccag tttgctttcc aactcatccg gcgtgcgaat agaaacgcca
     8041 atatggccat aggcttcagc caatttgacg aagtcaggca gcgaatccat ataagactgt
     8101 gagtgtcggc cagagtagat catgtcctgc cactgtttca ccataccgag atagcggttg
     8161 ttcaggttca acaccagcac cggcaagtta tattgcaatg cagtggataa ttcctgaata
     8221 ttcatctgga tactgccatc accggtgacg caaactacgg tttcgtctgg taacgccagc
     8281 ttgacgccaa gtgctgcggg caggccaaag cccatcgtcc ccagtccacc ggagttaatc
     8341 caacggcgtg gcttatcaaa cggatagtaa agtgcagcga acatctggtg ttgaccgaca
     8401 tcagaggtga cataggcatc accgctggtg aggcgatgta aggtttcgat caccgcctgc
     8461 ggcttgattt taccgctgtc tttgttgtaa ctcaggcaat tgcgggcacg ccattgttcg
     8521 atggattgcc accagtcacg caaactatcg caatcctgtg tgcaatcaat ctgagacaac
     8581 aactccagca tctgtaccaa gacttgtttg gcatcaccaa ctattggaat atctgcattt
     8641 acggttttcg aaattgaagt cgggtcgata tcgatgtgta ctaccgtggc attcgggcag
     8701 tatttcgcca gattgttggt ggtacggtca tcaaagcgca cgccaacggc aaaaatcaga
     8761 tccgtattgt gcatcgccat attggcttca aatgttccgt gcatccccag catacctacg
     8821 ctttggcgat gagttcctgg gaagctccct aaccccatca aagagctggt caccggcaaa
     8881 ttcagtttct cagcaagaac gagcagctct tcgtgacagg cagagttaat cgccccaccg
     8941 ccgacataca tgatgggttt cttggccgcc agaatagttt gcagcgcgcg tttaatctgc
     9001 ccacgatggc cttgtactgt ggggttataa gaacgcaggc taacctgatc cgggtaggcg
     9061 taaggcattt ttactgcagg tccaacaata tcttttggca aatcgataac gaccgggcct
     9121 gggcggccag ttgatgccag atagaaggct tttttcagta ctgttggaat atcttcagtc
     9181 cgcttcacca gaaaactgtg tttcaccact gggcgggaga tccccaccat gtcacattcc
     9241 tgaaaagcat cgtagcctat caatgagcta ggtacctgac cggaaagcac caccatcggt
     9301 actgagtcca tatacgcagt agcgataccg gtaatggcat tggtcgcacc tgggcctgaa
     9361 gtaaccagta ccacgccaac ctcgccggtt gctcgtgcat agccatcggc catgtgaacc
     9421 gcgccttgtt catggcgcac cagcacgtga tcgatgcctc cgaccgtgtg cagggcatcg
     9481 tagatatcaa gtacggcccc gccgggataa ccgaatacat gcttcacgcc ctgatcgatt
     9541 aacgatcgga caaccatctc ggctcctgac aacatctcca tgggttttgc ctccaggctt
     9601 agtttgctca ttggataacg ggaagtcatt tccacgggat cctgtaggaa aggcacttcg
     9661 ccctaattcc tatatttatt atttgtacgt aataacttat taacataacg tcagattttc
     9721 tggcaggcaa atggcaattc gctgcactaa agacaattta gttggccgca ctctgttttt
     9781 gttcacatta caaaaacaaa aaactgcctg agaagggctg accttagttt aaacaccgcc
     9841 aagataatta atcatagaac ttaatcaggc taagaatttt acgcgttggt agaagaaaaa
     9901 acgtgggatg ataccgggcc aggtaagtga aggggctgaa cgttcagaaa aacagcggct
     9961 gcctgtatca gaacaggcag caacatgatg acagtatcga ctaatcgcgg tacatagagt
    10021 caatttcatt ctgataacgc tggagaatga ttttacggcg cagcttcata gtaggggtca
    10081 attcacccgt ttccatggta aatgcctgcg gtaacaacgt aaagcgctta acctgctcga
    10141 acagcgccaa ctctttttgc atatctttca gcctttgttc aaacaaactg acaatatggc
    10201 tatggcgtaa taactctaac ctgtcgtggt atttcaggtt tatcgaacgg gcatactctt
    10261 caagtgactc aaaacagggc actatcagcg cggagacaaa tttgcgcgta tcagcaataa
    10321 tcgcaacctg ttcaataaaa cgatcctgac caagtgtgcc ctcaatcatt tgcggcgcaa
    10381 tatatttccc gccggaggtt ttcatcaagt ctttcagacg ttcggtgata aacaagttcc
    10441 cttgggcatc caacgccccg gcatcccccg ttttgagcca accatcttcg gtgaacgact
    10501 cagccgtctc ttgcggtttg ttaaaatagc cgcgcatcac aatgggaccg cgtacctgaa
    10561 tttcattctc tgcgcccaaa cgcacatcaa tccccggcag cggcttaccg atagagccga
    10621 aacggaaatc ttgctcttcc caacatgaaa cggtggcaca ggtttcggtc atgccatagc
    10681 cgtacttaat attgataccg attgcctgga aaaacaggat gatattgtca tctaaccgag
    10741 caccggcggc cggtaaaaag cgcacccgcc cgcctaatac cccacgcaat ttactcaata
    10801 ccaagcgatc cgccagcttg tacatctgcc cggataacaa tgataatttt tgcccacgtt
    10861 gcaggctttg gaattggcgc tcgccacacc ctaccgccca acggaacaac atccggcgat
    10921 gccattttgc cagagcgact ttgtcattga tggcactgaa cactttctcg taaaaccgag
    10981 ggacagcaca catcaccgtc ggctttactg ccagcatcgc tggtcgcacc caatcagtat
    11041 tgctgatata cacattttgg gcgccagtat gcatcacata gaagctccag gcccgctcaa
    11101 acacatggga taacggcagg aaactaagag agacatcctc tgctgtcagg gttaaacgct
    11161 gatcgtgcaa ataaagctgg gcggccatat tacggtaatc cagcatcaca cctttcggtt
    11221 caccggtggt tcccgaggta taaatcagtg tgaataaatc atttaagtcg cagctatcta
    11281 tacgtgcagt gagtagatgt tgctgtaccg catcaggctg ctgctcaaaa tcagctaagt
    11341 gttgggcata ttcacaaccg cgtaaatcaa ctgtagggtc taacacaata atctgagcaa
    11401 gttgcgggca cagcggcttt agcgttgcgg ctacatcaaa ttgcgtttgt ccgccgacaa
    11461 ataaaatacg cacatcggca tcattgagca cataggcggc ctgagcactg gtattggtgg
    11521 catacaatgg aacactgaca ccacgtaact gcaaaatagc taaatccgcc aacgaccagg
    11581 tcatgctgtt attggcaaaa atcccaatgc gctcttggat ggcaacccct agggataaca
    11641 gagcggctga aatttgggtg acatgggtat caacctgctg ccagcttaat tgctgttcgc
    11701 cctctggcga ccattcacgc aaggctattt ggtcagcacg gtggctgatt tgttggcgca
    11761 gtcggcgcac aaggtggtat tgctctaatg tgtgggtcat aacatcgccg ctcgctttgt
    11821 actcgccatc tttcaagtta ctgctgtgaa gcggcttgcg cttatccaaa tcaggtgact
    11881 ggaccagttt atcgggagcc tttcgcttag cgccgtcccg caccttgaaa tctattgggt
    11941 attgattatc cattaaagtg tactgcaact tgcagctaat tggcattcag cttacatgtg
    12001 ttcacttttt ttcgcgcagt ctacccgctc tatcggttag agcaaataaa attcagagta
    12061 gaagtgtgag ctgaaattga ctttgatgaa aaatagagca tttagggcgg caaggggagt
    12121 cggcaggaca atagcgtggc gttgaactga acaatggccg acaacaaaaa cacacgttaa
    12181 gttagttgtt accttacctg ctactgagaa taagataatt ccagcagcag gggttaacaa
    12241 aaataattac gcaggaatag taagttggct gagtagctct ttcatccact gatggccttt
    12301 atctctatca gtagattcat gccacgtgag ataacatggc cggtttgtat ttttccaagg
    12361 taaagagata agtttcagat taagcgcatc gctgtatttt tgagcaagcc aacgaggcgc
    12421 aattgccaca aagcaagttt gagatacaat attaagcaca ctattcatat cagtactttc
    12481 atatacaata gtttgagcac tgacctctga ctcataataa tgcccactga aagaacctac
    12541 tttatccaat gacactaccg catgtagctc tgaaaggagt tgttcttgcg taattgaatt
    12601 accaatacgg ggatggtctt tcgagactac cagaacggat tcatcattag agattgataa
    12661 ataatgaaag tccgggcgct caaatttggt ataacctata acaaattcgg tctcttgata
    12721 gcgcaactga tgctcaatat tatcattcaa ataggatttg atcatgatct gaacattagg
    12781 cgctaattgc ttaatgcatt gtattatttg tgccgtcaat ctgatatcta acggactaca
    12841 aacagataat ttaaagattc gcttactctt tttggcttca aagccggcac cgggcaactc
    12901 attttgaact aattgcaggg cttgcctcac cggcccaaac aactgacgag ccctggaggt
    12961 aggctgaata cctcggccat aacgaacgaa cagctcgtca ttaaacatca ctttcaaacg
    13021 ggcaacggca ttactcactg ctggctggga cattcccagt gactgggctg cacgtgtcac
    13081 gttatgcatt tgcatcacgg catcaaaaac ggttaataaa ttgaggtcga cacttcttaa
    13141 gtgaacatca ctaccttctt ttttagttac ttggtcgtcg gctactaagt tgtgttcaaa
    13201 catgcttaac tccactaagc tttatgcaga tggcatgatt aataaaagaa ctttactgat
    13261 atttatatac acctcaaaat atctttattc tcttactatt aacaatacca atgttctcat
    13321 cactactctt gttgagtaaa atgagtctca tccttgtata aatgcaaaag tattaattta
    13381 ctccctatct tttagtcaat aacgcccata gataaattcg cgaacaaagt attcacataa
    13441 aatatcttat atatatttcc acagaaattt acatcaaaaa tgccaacccg tttaatcata
    13501 agtaccaata ataaacttaa caagataatc acatcacaaa atgagatgat tgacaactat
    13561 gccattaata aataataaat tcatcaattc aaacttatta atccttagtt attagcatca
    13621 acatattaaa taatgaattt aatctcgtca tttaattata cccacagaac aaactcataa
    13681 catttaaaaa taacaaacgc tattatttat aatagtgatg aatatttata ttaaaaaata
    13741 tatattgtaa aaataataag atttattgtg aatttatcat tgtaataact aacaggctgc
    13801 tattacttat ctcattccct accaaggaga cctcaatgtg gcataccaaa accgacgttt
    13861 tcctctctag gcagatgatt tatggcccaa aatatcagag aagcacaata atccatatta
    13921 tgaagattat gccaaataaa acaaaatcat cagtatctat ttttagatta aaaaccctat
    13981 atatttaatt tttaggtttt ttatgtcgtt ataaggaatc tataacccgc gtaaccagtt
    14041 gaacacgcca ttttaaacaa aagttgacat gaccacaaaa ttcacgtatc aatttaggca
    14101 acgcattatt ttaaccaatg agaaactgaa aaattatgtt ctactcaacc cgtctactaa
    14161 gcctactact taacgcatct cacttgcgcg gtatgttggt ggacggaaat cagaactgat
    14221 tcagtcatca agattaacaa gcccgcgcaa atgcgcgggt ttttttttac ccgctaagcg
    14281 caaaagtaaa cacgacaagg aacaaaccat gagccaacaa gtcattattt tcgatacaac
    14341 attgcgcgac ggtgaacaag cattacaagc cagcctgagt gttaaagaga agctgcaaat
    14401 tgcgcttgca ctggaacgaa tgggtgtcga tgtcatggaa gtcggtttcc cggtttcctc
    14461 ccctggtgat tttgagtcag tgcgcaccat cgctcagcaa gtcaaaaaca gccgcgtttg
    14521 cgccttggct cgctgtgtag acaaggatat tgatgtcgcc gccgaagctt tgcgtattgc
    14581 tgaagccttc cgtattcatg tgttcttggc gacatccacc ttacatatcg aatctaaatt
    14641 aaagcgctca tttgatgatg tgttggcgat ggctgtccac tcggtgaaac gcgcccgcaa
    14701 ctataccaat gacgtagagt tctcttgtga agatgcaggc cgtacgccta ttgataacct
    14761 gtgtcgcatc gtagaagccg cgattaatgc cggcgctact accatcaata tccctgatac
    14821 tgtcggttac acgacccctt atcaattcgg cggaattatc accgacttgt atgagcgagt
    14881 gccaaatatt gataaagcca ttatctcggt ccattgccat gacgatttag gcatgtcagt
    14941 tgccaactcc atcactgcgg tccaagccgg tgcacgtcag gtagaaggta cgattaatgg
    15001 tttaggcgaa cgcgctggta actgttcact ggaagaagtg atcatggcta ttaaagtgcg
    15061 tgaaaagatg ttgggcgtgc ataccaatat caatcatcaa gagatttacc gcaccagcca
    15121 attggtcagt aagttatgca acatgccaat acccgctaac aaagccattg tcggcagtaa
    15181 tgctttcgct cactcatccg gtattcatca ggatggcgtg ctgaaaaatc gtgaaaacta
    15241 cgaaatcatg acaccgcaat ccatcggcct gaaagaagtg cagttgaacc tgacctcccg
    15301 ttctggtcgc gcagcggtca aacaccgcat ggaagagatg ggttatcagg ataaagatta
    15361 caatttggac tccttgtacg acgcattcct gaagttggcg gataaaaagg gccaggtatt
    15421 tgattacgat ttagaagcgt tagccttcat taataaacag caggaagagc cagaacacta
    15481 ccgtttagac tatttcagcg tgcagtctgg ctccagcgta atggcaacgg catccgtcaa
    15541 attggtctgt ggcgaagaca ttaaatcaga agcagccaca ggtaatggcc cggttgatgc
    15601 ggtgtatcag gccatcaatc gcattaccgg ttatgagatt gaactggtga aatatcaact
    15661 gtctgccaac ggtcagggta aagatgcatt gggtcaggtt gatatcgtgg ttgaccataa
    15721 aggtcgccgc ttccacggcg tgggtctggc aacagatatt gtcgagtcat ccgcgaaggc
    15781 gttggttcac gtattaaata acatctggcg cgctcatcag gtagatattg agaagcagcg
    15841 cttgcaacaa aataatcagg aaatggtgtg aacatgacta agacttatca tattgccgtt
    15901 ttgcccggag acggtattgg ccctgaagta atggctcagg caaataaagt attggatgcg
    15961 gtgcgtcagc gtttcggcat caagatttca accagcgctt atgatgtggg tggtgcagcc
    16021 atcgaccgtc acggcagccc gttacccgca gcgacggtca gcggatgtga gcaggctgac
    16081 gctatcttgt ttggctcggt aggcggcccg aaatgggaac atttgccccc ggcagaacaa
    16141 ccagagcgtg gtgcgttgtt gccattgcgc aagcacttta aattattcag taacttgcgc
    16201 ccggcgcggt tgtatcaagg gttagaagat ttctgcccat tgcgcagcga tattgccgct
    16261 aaaggttttg atattctgtg tgtgcgtgaa ttaactggcg gcatctactt cggccaaccc
    16321 aaaggccgtg aaggccaagg ccagcacgag cgcgcttttg ataccgaagt ttatcatcgc
    16381 tttgaaattg aacgtattgc ccgaattgcc tttgaatctg cgcgtaaacg ccgtggcaag
    16441 gttacttcta ttgataaagc caatgtgttg caaagctcta ttctgtggcg tgaagtggta
    16501 accgccattg cagccgatta cccagatgtt gcgttgtccc atatgtatat cgataacgcc
    16561 accatgcagt tgatcaaaga cccttcccag tttgatgtgt tgctgtgttc taacttgttt
    16621 ggcgatattt tgtctgatga gtgcgccatg ataacgggtt caatggggat gttgccgtcg
    16681 gccagcttga acgaacaagg tttcggttta tatgaacccg caggtggctc cgcacccgat
    16741 atcgcgggca aaaatatcgc caacccgatt gcccagattc tgtcattaac tctgctattg
    16801 cgtttcagtt tgggtaaaga cgatgccgcc gatgctattg agcgcgcgat caaccaggca
    16861 ttagaacaag gctatcgcac ggctgatttg gctggcgaag gtaaagccat cggtaccaac
    16921 gaaatgggcg atgttatcgc taaattcgta atggagggag tataaaatgg gcaagacgtc
    16981 atatcaaaac aagaccttat atcaaaaatt gtacgatgcg cacatcgttt acgaagcgcc
    17041 aaatgaaacg ccattgttgt acatagaccg ccatctggta catgaagtta cctcgccgca
    17101 agcctttgat ggtttgcgtg cgatgggtcg cccggtgcgt cagccgggca aaacctttgc
    17161 cacgatggac cacaacgttt caacccaaac caaagatatc aatgccagcg gcgaaatggc
    17221 ccgtatccag atgcaggagc tgattaagaa ctgtgctgag tttggtgtct ctttatatga
    17281 cctgaatcat ccgttccaag gcatcgtcca tgtgattggc cctgaacaag gtatgacgtt
    17341 accgggcatg accatcgtct gtggtgactc acacacggcg acccatggcg cattcggatc
    17401 attggccttc ggtatcggca cctcagaggt tgagcatgtg ctggcaaccc agaccctgaa
    17461 acagggccga gccaaaacca tgaaaatcga agttaacggt actgtcggtg cagggattac
    17521 cgccaaagac atcgtattgg cgattatcgg caaaaccggt agtgcaggcg gcaccgggca
    17581 tgtggtggag ttctgtggca gcgccattga agcactgagc atggaaggcc ggatgacatt
    17641 atgtaacatg gcaatcgaga tgggtgctaa agccggttta gtcgccccgg atgacaccac
    17701 tttcgactac ctgaaaggtc gtcagttcgc cccaaccggc gagcagtggg aacaaggtgt
    17761 ggcctactgg cgcacgttga aatctgatgc tgatgccaaa tttgacacta tcgtcaccct
    17821 ggatgccgca gatatcgcgc cacaagtcac ttggggcacc aacccaggcc aggtcattgc
    17881 ggttaatgac atgattcctg cgcctgagtc attcagtgat ccagttgaac gtgcctcggc
    17941 ggaaaaagcc ttggcgtata tggatttgcg ccccggcatt aagttgaccg aagtagcaat
    18001 tgataaagtc tttatcggtt cctgcaccaa ctcacgtatt gaagatttgc gtgccgctgc
    18061 cgccgtggca caagggcgta aagtcgcgac gggcgtgcaa gccattgtgg tacctggctc
    18121 aggcccggta aaagcgcagg cagaagcgga aggtctggac aagatcttta tcgaggccgg
    18181 ttttgagtgg cgcttgcccg gttgttccat gtgcttggcg atgaacaacg accgcctgga
    18241 acccggagag cgttgtgcct ccaccagcaa ccgtaacttt gaaggccgtc agggccgtgg
    18301 tggccgcaca catttggtta gcccggccat ggccgccgcc gccgctgtca gtggtcattt
    18361 tgctgatgtt cgcgacttag aagccgctac ccactaaccg gagacaccat tatggctaaa
    18421 tttactcaac acacgggttt ggtcgctccg ttggatgcgg caaatgtcga taccgacgcg
    18481 attatcccaa aacagttttt acaaaaagtg actcgcactg gcttcggcca acacttattt
    18541 aacgactggc gttttcttga cgatgcaggc caggtgccaa accctgagtt tgtgctgaac
    18601 caaccccgct atctgggtgc aactattctg ttggcgcgtg agaatttcgg ttgtggctcc
    18661 tcgcgggaac atgcgccatg ggcgctgacc gatttcggtt tcaaagtggt tattgcccct
    18721 agtttcgctg atatatttta cggtaactcg tttaataacc aattattacc ggtgacccta
    18781 agcgaagcgg atatcgatac cttattccaa ttggttaacg acaatgaagg cattgagttt
    18841 attgttgatt tggaagagca aaccgtgaag gccggtggca atagttattc ttttgaaata
    18901 gacagcttcc gccgccattg tatgattaat ggcttggaca gtattggcct gacgttgcaa
    18961 catgaaagta atatttctgc atatgaaaaa cagcaaccgg catttttacg ttaatttatt
    19021 ttaagttaat tttgtgagta tattgttggt gtcaggtaag ccctgaccca acaattcaaa
    19081 atctataaaa atactaatta aaaacgcatc ctttcttagt tcatttttca cgaaaaaagc
    19141 caaatcccat atcaatcaac ttgttatata acagtttctc aagttattat tttaactaag
    19201 tattaatgat tctgatattg actaatttga ttatattttg tgctggcggt cactttttat
    19261 ttcttcaacc acggtatgct gtcatcctcc atccacacct agagggcgcc ttatgacacg
    19321 cattgcattg cgttacgaag ctcgcatctc cggcgatagc cgagcctggt ttaatataga
    19381 ttaccgcctc gccaacgatt tcccgcgtta acacctccat tgcttattca gcttaggctg
    19441 aaaacactca tttatttatt ttattgccgt cattggtaat gcgaataact attttcgctc
    19501 gccatacatg actgcatttt taatattaat atatatgccc aaagtaattg gagttgcaga
    19561 gccgttagct gcgactgcaa gtatcaaggg tatttggagt cataagccat gaaacgtatc
    19621 ccagaaccct tccgtattaa aatggttgaa aatattcgga tgaccaaccg ggaagatcgt
    19681 gagaaagcat taatcgaagc aggctataac ccattcttac tgccgagtga agatgtctat
    19741 attgatttgc tcaccgactc tggcaccggt gcgatgagtg accgccaatg ggccgggtta
    19801 atgatgggcg atgaggccta tgccggttcg cgtaactact atcacttgtg tgaccaagtg
    19861 aagaaactga ttggctatcc gtttactatc ccaacccatc aggggcgtgg cgctgaacag
    19921 attctgttcc cttgcctgat tgcgaaaaaa caaaaggccg gtgggggtaa gaagccagtc
    19981 tttatttcca atttccactt tgataccacg gcggctcacg ttgagatgaa cggtgcgaag
    20041 gcaattaacg tagtcacacc gaaagccttt gataccgttg catattatga ctggaaaggg
    20101 gatttcgatt tagatcagtt aaaagcaacc attgccgaac atggtgcaga aaacgtggtt
    20161 tctattatta ccaccgtgac ctgtaatagc tccggcggtc agcctatttc tatgagcaat
    20221 atgcgcgaag tgtatcgcat cgctcagcag cacaatattc cagtggtgat cgactccgct
    20281 cgcttctgtg aaaatgcctg gtttatcaaa caaagagagc cgggttacgc ggataaatcc
    20341 gtcaaagaaa tcattttaga gatgtaccaa tatggcgata tgttaaccat gtctgccaaa
    20401 aaagacccca tggtaaatat tggtggatta tgttgtttcc gtaccgatga agacctattc
    20461 aacgatgttc gcatccgttg cgtgccaatg gaagggtttg tcacctatgg cggtttagct
    20521 ggtcgtgata tggaagcact ggccatcggg ctggaagaag gaatgaacga ggacttcctg
    20581 aagtaccgta tcggacaggt agaatatttg ggtgaccgcc tgcgggcggg cgggatccca
    20641 attcagtatc ctaccggcgg ccacgcagta tttgtcgatg ccaagattct gctgccacat
    20701 attccggctg agcaattccc agcccaagcc ttgaataacg aactgtatct ggaggcaggt
    20761 atccgcagtg tggaaattgg ctcgctactg ctggggcgag atccagaaac gggtaaacaa
    20821 aaaccgtcac cgctggaact gctgcgcctg acgatcccgc gccgggtcta caccaacgac
    20881 catatggatt acatcgccga cgcactgatt tcgctcaaat cacgcgctca tgatatcaaa
    20941 ggcttaacct ttacttacga accccctgtt ctgcgccact ttgttgcccg gttaaaaccg
    21001 gtcgaataaa gcgcgacgac cactctaaca acacgccccc tgttcacttc aggcaggggg
    21061 aatattgctg ccaaatcgct acctctataa gtggtaaaac cacacgagga caccctacta
    21121 tggcccaaac aacactggaa gatcaggtcg cagcacgtaa aattaaaaat ccttccctgc
    21181 tcggcggagc aatgattatt gcaggaacca tcgtcggcgc aggtatgttt tcattaccgg
    21241 tcgttatgtc agggatctgg ttttattggt ctattgccgt tttggttttt acctggtttt
    21301 gtatgcttca ttcaggatta atgatcctcg aagctaacct caattatcat accggtgcca
    21361 gttttgacac catcaccaaa gacttactgg gtaacggctg gaatgtaatc aatggcctga
    21421 ctgtcgcctt tgtgctctac attctgactt acgcttatat ctctgccagc ggttcggtta
    21481 ttcaacacac gttgcgcggg atggggatcg attttccggc ccgattaggc ggactgttct
    21541 ttgctctgtt cgtcgccttt attgtctggc tcagcaccac agccgtcagc cggatgacca
    21601 ccatcgtgct gggcgctaaa attctcacct tctttatgac gttcggcggg ctgttgggcc
    21661 atgtcgaacc ggtgaaactg tttaacctga gcgaagccaa tcccagctat ctgccttacc
    21721 tgctgatgac cttgccgttc tgcctggcat cattcggtta ccacggcaac gtccccagtt
    21781 tgatgaagta ttacggcaag aatccacatc gtatccgtaa ctgcctgctg attggtactc
    21841 tgctggcgct gaccctctat atcatctggc tggtcggcac gatgggcaat atcccacggc
    21901 cacaatttcg cgagatagcc agccagggcg gcaatattga tgtattggtc agtgcgcttg
    21961 gtgggatttt gcaaagttca tcgatggacc tgctgctaac tgtcttctca aacttcgcgg
    22021 tcgccagctc attccttggt gtaacattgg gactatttga ttatcttgcg gatttattta
    22081 agtttgacga cagtcgctta ggacgtggga agactgcggt tatcaccttc ctgccgccaa
    22141 tattgggtgg gctgatatat ccagatggtt tcatttacgc tatcggctat gccgggctgg
    22201 cagctaccgt ctgggcggcc atcgtaccgg cactgctggc acgcgcttca cgtaagcgct
    22261 tcggcagccc actgtatcgt gtgtggggcg gtaccccatt gattattgtg attttactgt
    22321 ttggggcggt taacgccatc gcccatattt tatccagtct gaacctgtta cccatctatt
    22381 aagctctttc gcaagcgccc tgcggggcgc tatgcctctc tcacccgagc acagatgatt
    22441 aacgccagaa tcgctaatcc catcgccacc acatataccg aattatggcc ccaggtttcg
    22501 gtcaataccc cttgcagaac cccagccaaa atcaccccag tggaaatact attggtaaac
    22561 agcgtggttg ctgctccggc cctgccaggc attaaatcct gaaaatagag catgccaatc
    22621 ccggcgacaa taccaataaa aatggcatta aaaatctgca aaagcatcag tgcagttttg
    22681 aatttgaata acaccaatcc ggtataaaac agcacacccg ccagcaccgc aaacagcata
    22741 attttgcgct taccaaaacg cctgaccgag taacccgcca gcagcataat agggatttcc
    22801 agtccggcag cggtccccat caacagacca gccaaccgct caggcaaccc caagtttgcc
    22861 gtgatataca gcggcatatc aatgatgtac atggtgttgc aagtccacat caacattgac
    22921 gcaataaaca acaacaaaac gtctttatcg gcaaacaaac tgccctgcac caccgctgac
    22981 gcatccacct ccggctctgc tcgctgcacc gaaggcagaa taaaccacac caccagcgca
    23041 ctgaggacaa aaataccggc ggcgatactg aacatcagcg taaaaccata attcagcgct
    23101 aacataaacg acagcggcgg gccgataacc caagccaatg aaagctgcgc acgcataatc
    23161 gagctaaaca tcaccacttc ccgcgccgag ctatcggcat attctcgcgc taaggcgaaa
    23221 atctgcggca tggcggtatt ggccaccgcc gccagcaaca caccggcggt gattagcgtc
    23281 agatagtcac gattaaaggc aaatagcagg cagttcccca ccgccatcaa gtaacaaacc
    23341 ataattagct tacggcggtc accacgtaaa tctgagcgtt tggccagtac aaagctgacg
    23401 gtaatcccgg caatggcatt gacggtataa aacaatccaa cccacagtgg gcgtactttc
    23461 acttcagtgc ttaagaacag gcttaatgtc ggtgcctgta acgcgccggc gataccggaa
    23521 agaaaagcca ccacaaagaa agcaagaaac accgggttaa tacggcggga aaaggtcaaa
    23581 gcagatttca ttccaggctc cagcgccaga aataacaatt aaacgctatg ctacagaagc
    23641 gtgtagattt atatagagaa aagtatacca gccacataaa tttcacatcc aaataatgga
    23701 tgcggtcgac cgtgtttcaa cctcaaggag gcaggataaa aaaagccagc agattgttga
    23761 acccactggc tggtgaaaaa caccattact cagaaatttt tggtacacag caaaataaga
    23821 cagggttcat ttaacaaata tcaacatcca ttatcattta ctacagctca caaagtgtgc
    23881 tcggttcggg cgataatatc gtcttgtgca tctggcgata gcgcggtaaa gaatgccgag
    23941 taacccgcaa cccgcaccac cagatcacgg tagcggtctg ggtgttgctt ggcatcaagc
    24001 aatgtctcac gcgatacaat gttgtactgc acatgccagc ccagatactc ctcaaagaag
    24061 gtacgcaaca tcatcatcag cttttcgcga tcacgcgggt tatctaaggt cgacggatta
    24121 agtttttgat tcagtagcac cccacccaga atagaagctg tcggcagttt tgacagtgag
    24181 ttaaacaccg ccgttggccc aaaatggtca gtaccggagg cagggcttgc gccttccgcc
    24241 agtgggctgt gggctttacg tccatccggc gttgccatcg ttgccgcacc aaacggcacg
    24301 ttagccgaaa tagacgatgt tccggcgtaa taggtaccgc cgatcgggcc gcgaccaaaa
    24361 cgggtattgt gatattgctt caattcatca atatacgtct gataagcgcg caccagcagt
    24421 tggtcaacat catcaatatc attaccgtat ttcggtgctg aattaaccag gtgttggcgt
    24481 aattgctcac cgttcaggcc agcaaagtca ttagctaatg ccgttgccag ttgctgttgg
    24541 ccgataagct gttgttcaaa caccagtttg cgcaccgctg ccaggctatt acccaaattg
    24601 gcaatgccca cctgcaagcc agaaacccag tcatagcgcg cgccgccctg cttaatactt
    24661 ttaccgcgct caatacaatc atccaccagt gcagaacaga caatatcgtg ggcattctct
    24721 tccaacacgg tatctaccac acactcaatt tcgatggatt ttcgcgtgta gtaacggatc
    24781 tgctgatccc attgcgccat cacttgtgag aaatcagtga agttaccttg tgataacccc
    24841 tgctcttgcg gcaagaatac ttgcccggaa gttgcatctt taccttgctc cagcgccgct
    24901 agcatcacgc gagcaaaatt aataaagctc atgccggtac agcgatagcc ccatttcccc
    24961 cccaccgcag tttcaatgca accgatggct gcgtaatcgt aagcatcctg tggttctacg
    25021 cccaatttga taaattcagg aataacaatt tcgtcattat taaatgccgg cataccaaag
    25081 ccgcagcgaa tgacctgcac acaagcatca aggaaatcat cactgatacc ggcatggtag
    25141 cgcacgctga gattcggctg agtcgaacgt aaacggccgc aggactccaa caccgcataa
    25201 gagagcgggt taaccgcatc aatcgcttta ccctgcacca gcttctgccc accaatagtg
    25261 acattctgat acagcgggct gcccgccgag gccttagagt gcgagccgga acggatctta
    25321 ttcacttcca gcaacttgag ccagcagcta tgcagcatct caatggcttt ttcgcggcta
    25381 agggtatttt ccagctccac gtcacggcga taccatggat agaggtattg gtcgaggcgg
    25441 ccaaaagaaa ccgagtgacc attagattca atttgcagca tcaattggat gaaatagcac
    25501 aactgcaagg cttgccagaa ggtttgtggc ggttggtgag caatcaactc gcagtttgtg
    25561 gcgatagtgt gtagttcaat gcgccgccaa tcacggcttt cttcttctgc catttgccgc
    25621 gcaaccgccg cataacgttc gatatgttca ctcagcgcca ccaatgaaat atcaatggct
    25681 ttcaggaatt gctctttatg caggtcactc cagtccgtca gttgtaaccg ttcgcggcga
    25741 ctcgccactt tactgcgcag gccatccagc cctttttcta acaataacgg gaagttaacc
    25801 gccaaatgcg catcaccgga agtcatatta ccttcggctt ttataatgcc ggtagccaat
    25861 aacgcttttt g
//
