LOCUS       NZ_CP107102.1          25483 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP107102.1 Yersinia enterocolitica strain NW56 chromosome.
ACCESSION   NZ_CP107102
VERSION     NZ_CP107102.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:52:57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3739013
            Orig. end    :: 3764496
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25483
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[3749013:3754496]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15483
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..25483
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25483
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="4"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(1116..2879)
                     /locus_tag="ctg1_3375"
                     /transl_table=11
                     /translation="MKAARPGKLKRQEEQASFISWRFALLCGCILLALVGLMLRTAYLQ
                     VINPDKLVREGDMRSLRVQEVPTARGMISDRSGRPLAVSVPVNAVWADPKELTERGGIT
                     LDTRWKALSDALEIPLDQLATRINANPKGRFVYLARQVNPAIGDYIHKLKLPGIYLRQE
                     SRRYYPAGQVMAHIIGVTNIDSQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIEDISS
                     VDSQAAHNLVLSVDERLQALVYRELNNAVAFNKAESGTAVLVDVNTGEVLAMANSPSYN
                     PNNLTGTPKDAMRNRAITDIFEPGSTVKPMVVMTALQHGVVKENSVLNTLPYFVNGHQI
                     KDVARYAELSVTGILQKSSNVGVSKLALAMPSSALVETYSKFGFGKATNLGLVGESSGL
                     YPKKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSMGIYRPLSITKVDPPVAGERVF
                     PEPLVRTVVHMMESVALPGGGGTKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGV
                     APASNPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPDALPTGDKSELV
                     TNTKEGSGGRS"
     PFAM_domain     complement(1221..2105)
                     /aSDomain="Transpeptidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00905.24"
                     /description="Penicillin binding protein transpeptidase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3375_0111"
                     /evalue="6.20E-82"
                     /label="ctg1_3375"
                     /locus_tag="ctg1_3375"
                     /protein_end="553"
                     /protein_start="258"
                     /score="275.3"
                     /tool="antismash"
                     /translation="GTAVLVDVNTGEVLAMANSPSYNPNNLTGTPKDAMRNRAITDIFE
                     PGSTVKPMVVMTALQHGVVKENSVLNTLPYFVNGHQIKDVARYAELSVTGILQKSSNVG
                     VSKLALAMPSSALVETYSKFGFGKATNLGLVGESSGLYPKKQRWSDIERATFSFGYGLM
                     VTPLQLARVYATIGSMGIYRPLSITKVDPPVAGERVFPEPLVRTVVHMMESVALPGGGG
                     TKAAIKGYRIAIKTGTAKKVGPDGKYMDRYLAYTAGVAPASNPRFALVVVINDPQAGKY
                     YGGAVSAPVFGAIM"
     PFAM_domain     complement(2223..2681)
                     /aSDomain="PBP_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03717.17"
                     /description="Penicillin-binding Protein dimerisation
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3375_0110"
                     /evalue="2.30E-18"
                     /label="ctg1_3375"
                     /locus_tag="ctg1_3375"
                     /protein_end="219"
                     /protein_start="66"
                     /score="67.3"
                     /tool="antismash"
                     /translation="PTARGMISDRSGRPLAVSVPVNAVWADPKELTERGGITLDTRWKA
                     LSDALEIPLDQLATRINANPKGRFVYLARQVNPAIGDYIHKLKLPGIYLRQESRRYYPA
                     GQVMAHIIGVTNIDSQGIEGVEKSFDRWLTGQPGERTVRKDRYGRVIED"
     CDS             complement(2940..3260)
                     /locus_tag="ctg1_3376"
                     /transl_table=11
                     /translation="VIGNERHGLVGVIGGDLLRNAKIPLILLIAVLVSAIFVVTTAHRT
                     RLLTAEREQLVLERDALDIEWRNLILEENALGDHSRVESIATDKLRMQHVDPSQENIVV
                     QQ"
     PFAM_domain     complement(2949..3230)
                     /aSDomain="FtsL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04999.15"
                     /description="Cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3376_0112"
                     /evalue="1.40E-34"
                     /label="ctg1_3376"
                     /locus_tag="ctg1_3376"
                     /protein_end="104"
                     /protein_start="10"
                     /score="118.0"
                     /tool="antismash"
                     /translation="GVIGGDLLRNAKIPLILLIAVLVSAIFVVTTAHRTRLLTAEREQL
                     VLERDALDIEWRNLILEENALGDHSRVESIATDKLRMQHVDPSQENIVV"
     aSDomain        complement(2952..3197)
                     /aSDomain="TIGR02209"
                     /aSTool="tigrfam"
                     /description="ftsL_broad: cell division protein FtsL"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3376_0037"
                     /evalue="3.80E-27"
                     /identifier="TIGR02209"
                     /label="ctg1_3376"
                     /locus_tag="ctg1_3376"
                     /protein_end="103"
                     /protein_start="21"
                     /score="92.0"
                     /tool="antismash"
                     /translation="KIPLILLIAVLVSAIFVVTTAHRTRLLTAEREQLVLERDALDIEW
                     RNLILEENALGDHSRVESIATDKLRMQHVDPSQENIV"
     CDS             complement(3257..4219)
                     /locus_tag="ctg1_3377"
                     /transl_table=11
                     /translation="MVDNNHIVDNNYKHTSVLLDEAVNGLNIRDNGIYIDGTFGRGGHS
                     RLILSQLGPEGRLIAIDRDPQAIEAAKSITDPRFSIVHGPFSDLAHYVRELDLVGRING
                     VLLDLGVSSPQLDDPERGFSFMRDGPLDMRMDPTRGISAAEWLMKASADDIAWVLKTFG
                     EERFAKRLAKAIVERNLTQPMTRTKELADLIANASPFREKHKHPATRSFQAIRIYINSE
                     LEEIERALDGALEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLR
                     SMGGRTLKSVGKMMPPDAEVAENPRARSSVLRFAERIKE"
     PFAM_domain     complement(3269..4186)
                     /aSDomain="Methyltransf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01795.21"
                     /description="MraW methylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3377_0113"
                     /evalue="4.60E-115"
                     /label="ctg1_3377"
                     /locus_tag="ctg1_3377"
                     /protein_end="317"
                     /protein_start="11"
                     /score="384.5"
                     /tool="antismash"
                     /translation="YKHTSVLLDEAVNGLNIRDNGIYIDGTFGRGGHSRLILSQLGPEG
                     RLIAIDRDPQAIEAAKSITDPRFSIVHGPFSDLAHYVRELDLVGRINGVLLDLGVSSPQ
                     LDDPERGFSFMRDGPLDMRMDPTRGISAAEWLMKASADDIAWVLKTFGEERFAKRLAKA
                     IVERNLTQPMTRTKELADLIANASPFREKHKHPATRSFQAIRIYINSELEEIERALDGA
                     LEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKSVG
                     KMMPPDAEVAENPRARSSVLRFAER"
     aSDomain        complement(3269..4192)
                     /aSDomain="TIGR00006"
                     /aSTool="tigrfam"
                     /description="TIGR00006: 16S rRNA
                     (cytosine(1402)-N(4))-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3377_0038"
                     /evalue="4.30E-125"
                     /identifier="TIGR00006"
                     /label="ctg1_3377"
                     /locus_tag="ctg1_3377"
                     /protein_end="317"
                     /protein_start="9"
                     /score="415.2"
                     /tool="antismash"
                     /translation="NNYKHTSVLLDEAVNGLNIRDNGIYIDGTFGRGGHSRLILSQLGP
                     EGRLIAIDRDPQAIEAAKSITDPRFSIVHGPFSDLAHYVRELDLVGRINGVLLDLGVSS
                     PQLDDPERGFSFMRDGPLDMRMDPTRGISAAEWLMKASADDIAWVLKTFGEERFAKRLA
                     KAIVERNLTQPMTRTKELADLIANASPFREKHKHPATRSFQAIRIYINSELEEIERALD
                     GALEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKS
                     VGKMMPPDAEVAENPRARSSVLRFAER"
     CDS             complement(4222..4680)
                     /locus_tag="ctg1_3378"
                     /transl_table=11
                     /translation="MFRGATMVNLDSKGRLAVPTRYRDLLNEESQGQMVCTIDLHQPCL
                     LLYTLPAWEVIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGL
                     NKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQDLSL"
     aSDomain        complement(4225..4680)
                     /aSDomain="TIGR00242"
                     /aSTool="tigrfam"
                     /description="TIGR00242: division/cell wall cluster
                     transcriptional repressor MraZ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3378_0039"
                     /evalue="7.30E-62"
                     /identifier="TIGR00242"
                     /label="ctg1_3378"
                     /locus_tag="ctg1_3378"
                     /protein_end="152"
                     /protein_start="0"
                     /score="205.5"
                     /tool="antismash"
                     /translation="MFRGATMVNLDSKGRLAVPTRYRDLLNEESQGQMVCTIDLHQPCL
                     LLYTLPAWEVIEQKLSRLSSMNPAERRVQRLLLGHASECQMDGAGRLLIAGTLRQHAGL
                     NKEVMLVGQFNKFELWDEQTWYQQVKDDIDAEQSTQEPLSERLQDLSL"
     PFAM_domain     complement(4255..4452)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3378_0115"
                     /evalue="1.90E-20"
                     /label="ctg1_3378"
                     /locus_tag="ctg1_3378"
                     /protein_end="142"
                     /protein_start="76"
                     /score="72.7"
                     /tool="antismash"
                     /translation="LLGHASECQMDGAGRLLIAGTLRQHAGLNKEVMLVGQFNKFELWD
                     EQTWYQQVKDDIDAEQSTQEP"
     PFAM_domain     complement(4456..4680)
                     /aSDomain="MraZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02381.20"
                     /description="MraZ protein, putative antitoxin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3378_0114"
                     /evalue="6.20E-22"
                     /label="ctg1_3378"
                     /locus_tag="ctg1_3378"
                     /protein_end="75"
                     /protein_start="0"
                     /score="77.4"
                     /tool="antismash"
                     /translation="MFRGATMVNLDSKGRLAVPTRYRDLLNEESQGQMVCTIDLHQPCL
                     LLYTLPAWEVIEQKLSRLSSMNPAERRVQR"
     CDS             5604..6044
                     /locus_tag="ctg1_3379"
                     /transl_table=11
                     /translation="MFSTGSRLRSAAADTFALVVYCFVIGMMIEIVISGMTFQQSLSSR
                     LVSIPVNILIAWPYGVYRDAFIRFARRHAGEHMWARNLADLLAYVSFQSPVYALILWSV
                     GADLEQITTAVASNALVSMAMGVAYGYFLEYCRKLFRVAGYV"
     PFAM_domain     5616..6029
                     /aSDomain="AlaE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06610.15"
                     /description="L-alanine exporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3379_0116"
                     /evalue="2.00E-72"
                     /label="ctg1_3379"
                     /locus_tag="ctg1_3379"
                     /protein_end="142"
                     /protein_start="4"
                     /score="241.9"
                     /tool="antismash"
                     /translation="GSRLRSAAADTFALVVYCFVIGMMIEIVISGMTFQQSLSSRLVSI
                     PVNILIAWPYGVYRDAFIRFARRHAGEHMWARNLADLLAYVSFQSPVYALILWSVGADL
                     EQITTAVASNALVSMAMGVAYGYFLEYCRKLFRV"
     CDS             complement(6100..7104)
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 209.4; E-value: 1.4e-63)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3380"
                     /transl_table=11
                     /translation="VKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREH
                     NYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPD
                     NEMRCIEHLLQRQVDAIIVSTALPPEHPFYQRWANDPLPIIALDRALDREHFISVVGAD
                     QEDAQMLAQELRSFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVDYLYANSYER
                     EAAGTLFAQWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPSNLTIATFGDNELLDF
                     LECPVLAVAQRHRDVAERVLELVLASLDEPHKPKPGLTRIRRNLFRRGSLSRK"
     aSDomain        complement(6121..7101)
                     /aSDomain="TIGR02417"
                     /aSTool="tigrfam"
                     /description="fruct_sucro_rep: D-fructose-responsive
                     transcription factor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3380_0040"
                     /evalue="3.60E-150"
                     /identifier="TIGR02417"
                     /label="ctg1_3380"
                     /locus_tag="ctg1_3380"
                     /protein_end="328"
                     /protein_start="1"
                     /score="497.7"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREHN
                     YHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDN
                     EMRCIEHLLQRQVDAIIVSTALPPEHPFYQRWANDPLPIIALDRALDREHFISVVGADQ
                     EDAQMLAQELRSFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVDYLYANSYERE
                     AAGTLFAQWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPSNLTIATFGDNELLDFL
                     ECPVLAVAQRHRDVAERVLELVLASLDEPHKPKPGLTRIRRNLFRR"
     PFAM_domain     complement(6193..6921)
                     /aSDomain="Peripla_BP_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00532.23"
                     /description="Periplasmic binding proteins and sugar
                     binding domain of LacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3380_0118"
                     /evalue="8.40E-15"
                     /label="ctg1_3380"
                     /locus_tag="ctg1_3380"
                     /protein_end="304"
                     /protein_start="61"
                     /score="55.0"
                     /tool="antismash"
                     /translation="RSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNE
                     MRCIEHLLQRQVDAIIVSTALPPEHPFYQRWANDPLPIIALDRALDREHFISVVGADQE
                     DAQMLAQELRSFPAESVLYLGALPELSVSFLREMGFREAWKDDPRKVDYLYANSYEREA
                     AGTLFAQWLKTHPMPQALFTTSFQLLQGVMDVTLKQSGRLPSNLTIATFGDNELLDFLE
                     CPVLAVAQRHRDVAERVLELV"
     PFAM_domain     complement(6955..7101)
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00356.23"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3380_0117"
                     /evalue="1.40E-18"
                     /label="ctg1_3380"
                     /locus_tag="ctg1_3380"
                     /protein_end="50"
                     /protein_start="1"
                     /score="66.4"
                     /tool="antismash"
                     /translation="KLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVDKVMAVVREHN
                     YHPN"
     CDS             complement(7328..7822)
                     /locus_tag="ctg1_3381"
                     /transl_table=11
                     /translation="MRRRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKR
                     CAEIFRGQIVDVTATLYTVQLAGTSDKLDAFLNAVREVAEIVEVARSGIVGVSRGDKIM
                     R"
     aSDomain        complement(7343..7816)
                     /aSDomain="TIGR00119"
                     /aSTool="tigrfam"
                     /description="acolac_sm: acetolactate synthase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3381_0041"
                     /evalue="4.00E-66"
                     /identifier="TIGR00119"
                     /label="ctg1_3381"
                     /locus_tag="ctg1_3381"
                     /protein_end="160"
                     /protein_start="2"
                     /score="219.8"
                     /tool="antismash"
                     /translation="RRILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRM
                     TIQTVGDAKVLEQIEKQLHKLVDVLRVSELVSGSHVEREIMLVKLQASGYGREEVKRCA
                     EIFRGQIVDVTATLYTVQLAGTSDKLDAFLNAVREVAEIVEVARSGIVGVSRGD"
     PFAM_domain     complement(7346..7570)
                     /aSDomain="ALS_ss_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10369.11"
                     /description="Small subunit of acetolactate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3381_0120"
                     /evalue="2.30E-23"
                     /label="ctg1_3381"
                     /locus_tag="ctg1_3381"
                     /protein_end="159"
                     /protein_start="84"
                     /score="82.3"
                     /tool="antismash"
                     /translation="REIMLVKLQASGYGREEVKRCAEIFRGQIVDVTATLYTVQLAGTS
                     DKLDAFLNAVREVAEIVEVARSGIVGVSRG"
     PFAM_domain     complement(7616..7810)
                     /aSDomain="ACT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01842.27"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3381_0119"
                     /evalue="8.20E-15"
                     /label="ctg1_3381"
                     /locus_tag="ctg1_3381"
                     /protein_end="69"
                     /protein_start="4"
                     /score="54.4"
                     /tool="antismash"
                     /translation="ILSVLLENESGALSRVVGLFSQRGYNIESLTVAPTDDPTLSRMTI
                     QTVGDAKVLEQIEKQLHKLV"
     CDS             complement(7825..9552)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 588.1;
                     E-value: 3.1e-178)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3382"
                     /transl_table=11
                     /translation="MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDH
                     VLVRHEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVP
                     SSLIGFDAFQECDMVGISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPK
                     DIVGPAVKMPYAYPEQVSLRSYNPTVQGHRGQIKRALQTILAAKRPIMYVGGGAINSAC
                     HEELLTLAEKLNLPVTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGV
                     RFDDRTTNNLAKYCPNAAVVHIDIDPTSISKTVEADIPIVGDAKQVLTQMLDLLPQIDC
                     AQDFDSLRDWWQSIEQWRARDCLSYAKDSGKIKPQAVIETLHRLTKGDAYVTSDVGQHQ
                     MFAALYYPFDKPRHWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQEL
                     STALQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVS
                     IRTPDELESKLADALTQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWLSKTERT"
     aSDomain        complement(7843..9543)
                     /aSDomain="TIGR00118"
                     /aSTool="tigrfam"
                     /description="acolac_lg: acetolactate synthase, large
                     subunit, biosynthetic type"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3382_0042"
                     /evalue="3.50E-278"
                     /identifier="TIGR00118"
                     /label="ctg1_3382"
                     /locus_tag="ctg1_3382"
                     /protein_end="570"
                     /protein_start="3"
                     /score="921.6"
                     /tool="antismash"
                     /translation="LSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLV
                     RHEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSL
                     IGFDAFQECDMVGISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIV
                     GPAVKMPYAYPEQVSLRSYNPTVQGHRGQIKRALQTILAAKRPIMYVGGGAINSACHEE
                     LLTLAEKLNLPVTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFD
                     DRTTNNLAKYCPNAAVVHIDIDPTSISKTVEADIPIVGDAKQVLTQMLDLLPQIDCAQD
                     FDSLRDWWQSIEQWRARDCLSYAKDSGKIKPQAVIETLHRLTKGDAYVTSDVGQHQMFA
                     ALYYPFDKPRHWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTA
                     LQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRT
                     PDELESKLADALTQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWLS"
     PFAM_domain     complement(7915..8373)
                     /aSDomain="TPP_enzyme_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02775.23"
                     /description="Thiamine pyrophosphate enzyme, C-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3382_0123"
                     /evalue="7.10E-50"
                     /label="ctg1_3382"
                     /locus_tag="ctg1_3382"
                     /protein_end="546"
                     /protein_start="393"
                     /score="168.9"
                     /tool="antismash"
                     /translation="DVGQHQMFAALYYPFDKPRHWINSGGLGTMGFGLPAALGVKLALP
                     DETVVCVTGDGSIQMNIQELSTALQYNLPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSY
                     MDSLPDFVKLAEAYGHIGVSIRTPDELESKLADALTQLSETNRLVFVDV"
     PFAM_domain     complement(8563..8967)
                     /aSDomain="TPP_enzyme_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00205.24"
                     /description="Thiamine pyrophosphate enzyme, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3382_0122"
                     /evalue="4.30E-48"
                     /label="ctg1_3382"
                     /locus_tag="ctg1_3382"
                     /protein_end="330"
                     /protein_start="195"
                     /score="162.6"
                     /tool="antismash"
                     /translation="IKRALQTILAAKRPIMYVGGGAINSACHEELLTLAEKLNLPVTSS
                     LMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDRTTNNLAKYCPNAA
                     VVHIDIDPTSISKTVEADIPIVGDAKQVLTQ"
     PFAM_domain     complement(9043..9540)
                     /aSDomain="TPP_enzyme_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02776.20"
                     /description="Thiamine pyrophosphate enzyme, N-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3382_0121"
                     /evalue="1.20E-57"
                     /label="ctg1_3382"
                     /locus_tag="ctg1_3382"
                     /protein_end="170"
                     /protein_start="4"
                     /score="194.4"
                     /tool="antismash"
                     /translation="SGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVR
                     HEQGAVHMADGYARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLI
                     GFDAFQECDMVGISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVG
                     PAV"
     CDS             complement(10001..11800)
                     /NRPS_PKS="Domain: AMP-binding (14-468). E-value: 7.5e-91.
                     Score: 296.5. Matches aSDomain:
                     nrpspksdomains_ctg1_3383_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     276.2; E-value: 6.9e-84)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3383"
                     /sec_met_domain="AMP-binding (E-value: 3e-91, bitscore:
                     303.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQILDQYHLVRRLRQQISQRTDKVAFREWSPEGENQLTWRQIDA
                     HVTRISAALLSLGAAIQERIGIFANNSMAWSLADLAILQIRGVSVPLYATNTTAQAAYV
                     VNDADVRILFVGGQAQFDVAITLKPLCPQLSHIVVLDPGVDLRGCEYAQHLADFEQQPD
                     AVQQHLLSARIDGCDLSDLFTLIYTSGTTGEPKGVMLEYRNMAAQLYLHDQRLTLTSDD
                     TSLSFLPLSHVFERAWSFYVMHTGAQNVYISDTNWVRAAMQAVKPTVMCAVPRFYEKVF
                     SAINDKVALAKWHRRMLFRWAVGCGERKFQNLQSGQTSSWFSEQMYKLADRLVLSKLRG
                     VLGGKVRFLPAAGARLDDNIILFFQAIGINIKYGYGMTETCATVSCWEEKDFRFGSIGK
                     PLPGIEVRLGAENEIQVRGPIVMRGYFNKPQETAESFTEDGWLKTGDAGALDPQGNLFI
                     TERLKDLMKTSGGKYIAPQMIEGTLGQDRFIEQIAIIADTRKFVSALIVPCFESLEEYA
                     HSINLKYHDRLELLRHSHIVSLFEQRLKDMQKELAKFEQVKRFTLLPQAFTMETGELTP
                     TMKLRRKIILQRYQNEIDSMYRD"
     aSDomain        complement(10397..11758)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3383_AMP-binding.1"
                     /evalue="7.50E-91"
                     /label="ctg1_3383_AMP-binding.1"
                     /locus_tag="ctg1_3383"
                     /protein_end="468"
                     /protein_start="14"
                     /score="296.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RQQISQRTDKVAFREWSPEGENQLTWRQIDAHVTRISAALLSLGA
                     AIQERIGIFANNSMAWSLADLAILQIRGVSVPLYATNTTAQAAYVVNDADVRILFVGGQ
                     AQFDVAITLKPLCPQLSHIVVLDPGVDLRGCEYAQHLADFEQQPDAVQQHLLSARIDGC
                     DLSDLFTLIYTSGTTGEPKGVMLEYRNMAAQLYLHDQRLTLTSDDTSLSFLPLSHVFER
                     AWSFYVMHTGAQNVYISDTNWVRAAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKWHR
                     RMLFRWAVGCGERKFQNLQSGQTSSWFSEQMYKLADRLVLSKLRGVLGGKVRFLPAAGA
                     RLDDNIILFFQAIGINIKYGYGMTETCATVSCWEEKDFRFGSIGKPLPGIEVRLGAENE
                     IQVRGPIVMRGYFNKPQETAESFTEDGWLKTGDAGALDPQGNLFITERLKDLMKT"
     PFAM_domain     complement(10397..11758)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3383_0124"
                     /evalue="7.30E-95"
                     /label="ctg1_3383"
                     /locus_tag="ctg1_3383"
                     /protein_end="468"
                     /protein_start="14"
                     /score="318.1"
                     /tool="antismash"
                     /translation="RQQISQRTDKVAFREWSPEGENQLTWRQIDAHVTRISAALLSLGA
                     AIQERIGIFANNSMAWSLADLAILQIRGVSVPLYATNTTAQAAYVVNDADVRILFVGGQ
                     AQFDVAITLKPLCPQLSHIVVLDPGVDLRGCEYAQHLADFEQQPDAVQQHLLSARIDGC
                     DLSDLFTLIYTSGTTGEPKGVMLEYRNMAAQLYLHDQRLTLTSDDTSLSFLPLSHVFER
                     AWSFYVMHTGAQNVYISDTNWVRAAMQAVKPTVMCAVPRFYEKVFSAINDKVALAKWHR
                     RMLFRWAVGCGERKFQNLQSGQTSSWFSEQMYKLADRLVLSKLRGVLGGKVRFLPAAGA
                     RLDDNIILFFQAIGINIKYGYGMTETCATVSCWEEKDFRFGSIGKPLPGIEVRLGAENE
                     IQVRGPIVMRGYFNKPQETAESFTEDGWLKTGDAGALDPQGNLFITERLKDLMKT"
     CDS_motif       complement(10493..10564)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_3383_0002"
                     /evalue="3.20E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_3383"
                     /protein_end="436"
                     /protein_start="412"
                     /score="25.9"
                     /tool="antismash"
                     /translation="EIQVRGPIVMRGYFNKPQETAESF"
     CDS_motif       complement(11198..11248)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_3383_0001"
                     /evalue="5.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_3383"
                     /protein_end="201"
                     /protein_start="184"
                     /score="25.2"
                     /tool="antismash"
                     /translation="LIYTSGTTGEPKGVMLE"
     CDS             complement(12133..12693)
                     /gene_functions="regulatory (smcogs) SMCOG1125:LysR family
                     transcriptional regulator (Score: 102.3; E-value: 5.4e-31)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3384"
                     /transl_table=11
                     /translation="MKTSIINGSEVSRLSVAIHLNENIEHQLRYQETEFVIGYTKFERS
                     DFHHVSLSNDELVLAVSKNHPRIDNSITQEQLLSELHAIVSLDKVGSFSQLYYESAIST
                     KTIAYESTDMNSVLNIVSQTSFVAIAPRWLVQTYSEALNLKLISLPWEETCRPCYLTWH
                     ESTDRDKGHQWMKELLSQLSIPS"
     PFAM_domain     complement(12154..12654)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3384_0125"
                     /evalue="1.60E-15"
                     /label="ctg1_3384"
                     /locus_tag="ctg1_3384"
                     /protein_end="180"
                     /protein_start="13"
                     /score="57.2"
                     /tool="antismash"
                     /translation="LSVAIHLNENIEHQLRYQETEFVIGYTKFERSDFHHVSLSNDELV
                     LAVSKNHPRIDNSITQEQLLSELHAIVSLDKVGSFSQLYYESAISTKTIAYESTDMNSV
                     LNIVSQTSFVAIAPRWLVQTYSEALNLKLISLPWEETCRPCYLTWHESTDRDKGHQWMK
                     ELLS"
     CDS             complement(12656..12826)
                     /locus_tag="ctg1_3385"
                     /transl_table=11
                     /translation="MSGKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQMSPTEY
                     ENQYYQRLGSV"
     CDS             13921..15483
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 427.8;
                     E-value: 9.2e-130)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3386"
                     /sec_met_domain="HMGL-like (E-value: 6.5e-107, bitscore:
                     354.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEV
                     GFPVSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATST
                     LHIESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRIVEAAINAGA
                     TTINIPDTVGYTTPYQFGGIITDLYQRVPNIDKAIISVHCHDDLGMSVANSITAVQAGA
                     RQVEGTINGLGERAGNCSLEEVIMAIKVRENMLGVHTNINHQEIYRTSQLVSKLCNMPI
                     PANKAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPQSIGLKEVQLNLTSRSGRAAVKHR
                     MEEMGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHYRLDYFSVQ
                     SGSSVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSANGQGK
                     DALGQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLNNIWRAHQVEIEKQRLQQNNQ
                     EMV"
     PFAM_domain     13930..14739
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3386_0126"
                     /evalue="2.50E-107"
                     /label="ctg1_3386"
                     /locus_tag="ctg1_3386"
                     /protein_end="273"
                     /protein_start="3"
                     /score="358.4"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFP
                     VSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHI
                     ESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRIVEAAINAGATTI
                     NIPDTVGYTTPYQFGGIITDLYQRVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGLGERAGNCSLEEVIMAIKVRENMLGVHTNINHQEIYRTSQLV"
     aSDomain        13930..15411
                     /aSDomain="TIGR00973"
                     /aSTool="tigrfam"
                     /description="leuA_bact: 2-isopropylmalate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3386_0043"
                     /evalue="8.20E-252"
                     /identifier="TIGR00973"
                     /label="ctg1_3386"
                     /locus_tag="ctg1_3386"
                     /protein_end="497"
                     /protein_start="3"
                     /score="833.9"
                     /tool="antismash"
                     /translation="QVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFP
                     VSSPGDFESVRTIAQQVKNSRVCALARCVDKDIDVAAEALRIAEAFRIHVFLATSTLHI
                     ESKLKRSFDDVLAMAVHSVKRARNYTDDVEFSCEDAGRTPIDNLCRIVEAAINAGATTI
                     NIPDTVGYTTPYQFGGIITDLYQRVPNIDKAIISVHCHDDLGMSVANSITAVQAGARQV
                     EGTINGLGERAGNCSLEEVIMAIKVRENMLGVHTNINHQEIYRTSQLVSKLCNMPIPAN
                     KAIVGSNAFAHSSGIHQDGVLKNRENYEIMTPQSIGLKEVQLNLTSRSGRAAVKHRMEE
                     MGYQDKDYNLDSLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHYRLDYFSVQSGS
                     SVMATASVKLVCGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSANGQGKDAL
                     GQVDIVVDHKGRRFHGVGLATDIVESSAKALVHVLN"
     PFAM_domain     15025..15417
                     /aSDomain="LeuA_dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08502.12"
                     /description="LeuA allosteric (dimerisation) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3386_0127"
                     /evalue="8.90E-37"
                     /label="ctg1_3386"
                     /locus_tag="ctg1_3386"
                     /protein_end="499"
                     /protein_start="368"
                     /score="126.0"
                     /tool="antismash"
                     /translation="QVFDYDLEALAFINKQQEEPEHYRLDYFSVQSGSSVMATASVKLV
                     CGEEIKSEAATGNGPVDAVYQAINRITDYPIELVKYQLSANGQGKDALGQVDIVVDHKG
                     RRFHGVGLATDIVESSAKALVHVLNNI"
     CDS             15486..16577
                     /locus_tag="ctg1_3387"
                     /transl_table=11
                     /translation="MTKTYHIAVLPGDGIGPEVMAQANKVLDAVRQRFGIKISTSAYDV
                     GGAAIDRHGSPLPPATVSGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKL
                     FSNLRPARLYQGLEDFCPLRSDIAAKGFDILCVRELTGGIYFGQPKGREGQGMHERAFD
                     TEVYHRFEIERIARIAFESARKRGGKVTSIDKANVLQSSILWREVVTAIAADYPDVALS
                     HMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYE
                     PAGGSAPDIAGKNIANPIAQILSLALLLRFSLGKDDAAAAIENAINQALEQGYRTADLA
                     GDGKAIGTNEMGDIIAKFVAEGV"
     aSDomain        15501..16547
                     /aSDomain="TIGR00169"
                     /aSTool="tigrfam"
                     /description="leuB: 3-isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3387_0044"
                     /evalue="1.30E-165"
                     /identifier="TIGR00169"
                     /label="ctg1_3387"
                     /locus_tag="ctg1_3387"
                     /protein_end="354"
                     /protein_start="5"
                     /score="548.6"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEVMAQANKVLDAVRQRFGIKISTSAYDVGGAAI
                     DRHGSPLPPATVSGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLR
                     PARLYQGLEDFCPLRSDIAAKGFDILCVRELTGGIYFGQPKGREGQGMHERAFDTEVYH
                     RFEIERIARIAFESARKRGGKVTSIDKANVLQSSILWREVVTAIAADYPDVALSHMYID
                     NATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSLALLLRFSLGKDDAAAAIENAINQALEQGYRTADLAGDGKA
                     IGTNEMGDI"
     PFAM_domain     15501..16550
                     /aSDomain="Iso_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00180.22"
                     /description="Isocitrate/isopropylmalate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3387_0128"
                     /evalue="4.50E-136"
                     /label="ctg1_3387"
                     /locus_tag="ctg1_3387"
                     /protein_end="355"
                     /protein_start="5"
                     /score="453.7"
                     /tool="antismash"
                     /translation="HIAVLPGDGIGPEVMAQANKVLDAVRQRFGIKISTSAYDVGGAAI
                     DRHGSPLPPATVSGCEQADAILFGSVGGPKWEHLPPAEQPERGALLPLRKHFKLFSNLR
                     PARLYQGLEDFCPLRSDIAAKGFDILCVRELTGGIYFGQPKGREGQGMHERAFDTEVYH
                     RFEIERIARIAFESARKRGGKVTSIDKANVLQSSILWREVVTAIAADYPDVALSHMYID
                     NATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGS
                     APDIAGKNIANPIAQILSLALLLRFSLGKDDAAAAIENAINQALEQGYRTADLAGDGKA
                     IGTNEMGDII"
     CDS             16579..18009
                     /locus_tag="ctg1_3388"
                     /transl_table=11
                     /translation="MSKTLYQNKTLYQKLYDAHIVYEAPNETPLLYIDRHLVHEVTSPQ
                     AFDGLRAMGRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLY
                     DLNHPFQGIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQT
                     LKQGRAKTMKIEVNGEVGPGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGR
                     MTLCNMAIEMGAKAGLVAPDDTTFNYLKGRQFAPTGKQWEQGVAYWRTLKSDADAKFDT
                     VVTLDAADIAPQVTWGTNPGQVIAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKL
                     TEVAIDKVFIGSCTNSRIEDLRAAAAVAQGRKVASGVQAIVVPGSGPVKAQAEAEGLDK
                     IFIEAGFEWRLPGCSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAA
                     AAVSGHFADVRDLSAATH"
     aSDomain        16600..17991
                     /aSDomain="TIGR00170"
                     /aSTool="tigrfam"
                     /description="leuC: 3-isopropylmalate dehydratase, large
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3388_0045"
                     /evalue="3.80E-268"
                     /identifier="TIGR00170"
                     /label="ctg1_3388"
                     /locus_tag="ctg1_3388"
                     /protein_end="471"
                     /protein_start="7"
                     /score="887.6"
                     /tool="antismash"
                     /translation="NKTLYQKLYDAHIVYEAPNETPLLYIDRHLVHEVTSPQAFDGLRA
                     MGRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLYDLNHPFQ
                     GIVHVIGPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAK
                     TMKIEVNGEVGPGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMA
                     IEMGAKAGLVAPDDTTFNYLKGRQFAPTGKQWEQGVAYWRTLKSDADAKFDTVVTLDAA
                     DIAPQVTWGTNPGQVIAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDK
                     VFIGSCTNSRIEDLRAAAAVAQGRKVASGVQAIVVPGSGPVKAQAEAEGLDKIFIEAGF
                     EWRLPGCSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSGHF
                     ADVRDL"
     PFAM_domain     16618..17967
                     /aSDomain="Aconitase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00330.22"
                     /description="Aconitase family (aconitate hydratase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3388_0129"
                     /evalue="3.40E-164"
                     /label="ctg1_3388"
                     /locus_tag="ctg1_3388"
                     /protein_end="463"
                     /protein_start="13"
                     /score="547.3"
                     /tool="antismash"
                     /translation="KLYDAHIVYEAPNETPLLYIDRHLVHEVTSPQAFDGLRAMGRPVR
                     QPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCAEFGVSLYDLNHPFQGIVHVI
                     GPEQGMTLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQGRAKTMKIEV
                     NGEVGPGITAKDIVLAIIGKTGSAGGTGHVVEFCGSAIEALSMEGRMTLCNMAIEMGAK
                     AGLVAPDDTTFNYLKGRQFAPTGKQWEQGVAYWRTLKSDADAKFDTVVTLDAADIAPQV
                     TWGTNPGQVIAVNQIIPAPESFSDPVERASAEKALAYMDLRPGIKLTEVAIDKVFIGSC
                     TNSRIEDLRAAAAVAQGRKVASGVQAIVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPG
                     CSMCLAMNNDRLEPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVSG"
     CDS             18024..18662
                     /locus_tag="ctg1_3389"
                     /transl_table=11
                     /translation="MTKFTQHTGFAQHTGFAQHRGLVAPLDAANVDTDAIIPKQFLQKV
                     TRTGFGQHLFNDWRFLDDAGKVPNPEFVLNQPRYQGATILLARENFGCGSSREHAPWAL
                     TDFGFKVVIAPSFADIFYGNSFNNQLLPVTLSEGDIDTLFQLVKENEGIEFIVDLEHQT
                     VNAGGKSYSFEIDSFRRHCMINGLDSIGLTLQHENNISAYEKQQPEFLR"
     aSDomain        18066..18623
                     /aSDomain="TIGR00171"
                     /aSTool="tigrfam"
                     /description="leuD: 3-isopropylmalate dehydratase, small
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3389_0046"
                     /evalue="8.70E-97"
                     /identifier="TIGR00171"
                     /label="ctg1_3389"
                     /locus_tag="ctg1_3389"
                     /protein_end="200"
                     /protein_start="14"
                     /score="320.4"
                     /tool="antismash"
                     /translation="GFAQHRGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFNDWR
                     FLDDAGKVPNPEFVLNQPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPSFA
                     DIFYGNSFNNQLLPVTLSEGDIDTLFQLVKENEGIEFIVDLEHQTVNAGGKSYSFEIDS
                     FRRHCMINGLDSIGLTLQHENNI"
     PFAM_domain     18069..18434
                     /aSDomain="Aconitase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00694.21"
                     /description="Aconitase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3389_0130"
                     /evalue="8.90E-40"
                     /label="ctg1_3389"
                     /locus_tag="ctg1_3389"
                     /protein_end="137"
                     /protein_start="15"
                     /score="136.1"
                     /tool="antismash"
                     /translation="FAQHRGLVAPLDAANVDTDAIIPKQFLQKVTRTGFGQHLFNDWRF
                     LDDAGKVPNPEFVLNQPRYQGATILLARENFGCGSSREHAPWALTDFGFKVVIAPSFAD
                     IFYGNSFNNQLLPVTLSE"
     CDS             18960..19058
                     /locus_tag="ctg1_3390"
                     /transl_table=11
                     /translation="MTRIALRYQARISGDSRAWFNIDYRLANDFPR"
     aSDomain        18993..19052
                     /aSDomain="TIGR02616"
                     /aSTool="tigrfam"
                     /description="tnaC_leader: tryptophanase leader peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3390_0047"
                     /evalue="2.10E-08"
                     /identifier="TIGR02616"
                     /label="ctg1_3390"
                     /locus_tag="ctg1_3390"
                     /protein_end="31"
                     /protein_start="11"
                     /score="31.9"
                     /tool="antismash"
                     /translation="ISGDSRAWFNIDYRLANDFP"
     CDS             19213..20613
                     /NRPS_PKS="Domain: Beta_elim_lyase (45-431). E-value:
                     2.6e-99. Score: 323.9. Matches aSDomain:
                     nrpspksdomains_ctg1_3391_Beta_elim_lyase.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg1_3391"
                     /transl_table=11
                     /translation="MKRIPEPFRIKMVENIRMTNREAREKALIEAGYNPFLLPSEDVYI
                     DLLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGYPFTIPTHQGRGAEQ
                     ILFPCLIAKKQKAGGAKNPVFISNFHFDTTAAHVEMNGAKAINVVTPKAFDTVAYYDWK
                     GDFDLDQLKATIAEYGADNVVSIITTVTCNSSGGQPISMSNMREVYRIAQQHNIPVVID
                     SARFCENAWFIKQREPGYGDKSIKEIILEMYQYGDMLTMSAKKDPMVNIGGLCCFRTDE
                     DLFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLTYRIGQVEYLGERLRA
                     GGIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNALYLEAGIRSVEIGSLLLGRDP
                     QTGKQKPSPLELLRLTIPRRVYTNDHMDYIADALISLKSRAEEIKGLTFTYEPPVLRHF
                     VARLKPIE"
     aSDomain        19216..20607
                     /aSDomain="TIGR02617"
                     /aSTool="tigrfam"
                     /description="tnaA_trp_ase: tryptophanase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3391_0048"
                     /evalue="3.70E-260"
                     /identifier="TIGR02617"
                     /label="ctg1_3391"
                     /locus_tag="ctg1_3391"
                     /protein_end="465"
                     /protein_start="1"
                     /score="861.6"
                     /tool="antismash"
                     /translation="KRIPEPFRIKMVENIRMTNREAREKALIEAGYNPFLLPSEDVYID
                     LLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGYPFTIPTHQGRGAEQI
                     LFPCLIAKKQKAGGAKNPVFISNFHFDTTAAHVEMNGAKAINVVTPKAFDTVAYYDWKG
                     DFDLDQLKATIAEYGADNVVSIITTVTCNSSGGQPISMSNMREVYRIAQQHNIPVVIDS
                     ARFCENAWFIKQREPGYGDKSIKEIILEMYQYGDMLTMSAKKDPMVNIGGLCCFRTDED
                     LFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLTYRIGQVEYLGERLRAG
                     GIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNALYLEAGIRSVEIGSLLLGRDPQ
                     TGKQKPSPLELLRLTIPRRVYTNDHMDYIADALISLKSRAEEIKGLTFTYEPPVLRHFV
                     ARLKPI"
     aSDomain        19348..20505
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3391_Beta_elim_lyase.1"
                     /evalue="2.60E-99"
                     /label="ctg1_3391_Beta_elim_lyase.1"
                     /locus_tag="ctg1_3391"
                     /protein_end="431"
                     /protein_start="45"
                     /score="323.9"
                     /tool="antismash"
                     /translation="DLLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGY
                     PFTIPTHQGRGAEQILFPCLIAKKQKAGGAKNPVFISNFHFDTTAAHVEMNGAKAINVV
                     TPKAFDTVAYYDWKGDFDLDQLKATIAEYGADNVVSIITTVTCNSSGGQPISMSNMREV
                     YRIAQQHNIPVVIDSARFCENAWFIKQREPGYGDKSIKEIILEMYQYGDMLTMSAKKDP
                     MVNIGGLCCFRTDEDLFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLTY
                     RIGQVEYLGERLRAGGIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNALYLEAGI
                     RSVEIGSLLLGRDPQTGKQKPSPLELLRLTIPRRVYTNDHMDYIAD"
     PFAM_domain     19348..20505
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01212.23"
                     /description="Beta-eliminating lyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3391_0131"
                     /evalue="9.20E-97"
                     /label="ctg1_3391"
                     /locus_tag="ctg1_3391"
                     /protein_end="431"
                     /protein_start="45"
                     /score="323.9"
                     /tool="antismash"
                     /translation="DLLTDSGTGAMSDRQWAGLMMGDEAYAGSRNYYHLCDQVKKLIGY
                     PFTIPTHQGRGAEQILFPCLIAKKQKAGGAKNPVFISNFHFDTTAAHVEMNGAKAINVV
                     TPKAFDTVAYYDWKGDFDLDQLKATIAEYGADNVVSIITTVTCNSSGGQPISMSNMREV
                     YRIAQQHNIPVVIDSARFCENAWFIKQREPGYGDKSIKEIILEMYQYGDMLTMSAKKDP
                     MVNIGGLCCFRTDEDLFNDVRIRCVPMEGFVTYGGLAGRDMEALAIGLEEGMNEDFLTY
                     RIGQVEYLGERLRAGGIPIQYPTGGHAVFVDAKILLPHIPAEQFPAQALNNALYLEAGI
                     RSVEIGSLLLGRDPQTGKQKPSPLELLRLTIPRRVYTNDHMDYIAD"
     CDS             20722..21984
                     /locus_tag="ctg1_3392"
                     /transl_table=11
                     /translation="MAQTTLEDQVTAAKIKNPSLLGGAMIIAGTIVGAGMFSLPVVMSG
                     IWFYWSIAVLVFTWFCMLHSGLMILEANLNYHTGASFDTITKDLLGNGWNVINGLTVAF
                     VLYILTYAYISASGSVIQHTLRGMGIDFPARLGGLFFALFVAFIVWLSTTAVSRMTTIV
                     LGAKILTFFMTFGGLLGHVEPVKLFNLSDANPSYLPYLLMTLPFCLASFGYHGNVPSLM
                     KYYGKNPHRIRNCLLFGTLLALALYIIWLVGTMGNIPRPQFREIASQGGNIDVLVSALG
                     GILKSSSMDLLLTVFSNFAVASSFLGVTLGLFDYLADLFKFNDSRLGRAKTAAITFLPP
                     ILGGLIYPDGFIYAIGYAGLAATVWAAIVPALLARASRKRFGSPLYRVWGGTPMIVLIL
                     LFGAINAIAHILSSLNLLPVY"
     PFAM_domain     20767..21948
                     /aSDomain="Trp_Tyr_perm"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03222.15"
                     /description="Tryptophan/tyrosine permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3392_0132"
                     /evalue="4.20E-151"
                     /label="ctg1_3392"
                     /locus_tag="ctg1_3392"
                     /protein_end="409"
                     /protein_start="15"
                     /score="503.6"
                     /tool="antismash"
                     /translation="KNPSLLGGAMIIAGTIVGAGMFSLPVVMSGIWFYWSIAVLVFTWF
                     CMLHSGLMILEANLNYHTGASFDTITKDLLGNGWNVINGLTVAFVLYILTYAYISASGS
                     VIQHTLRGMGIDFPARLGGLFFALFVAFIVWLSTTAVSRMTTIVLGAKILTFFMTFGGL
                     LGHVEPVKLFNLSDANPSYLPYLLMTLPFCLASFGYHGNVPSLMKYYGKNPHRIRNCLL
                     FGTLLALALYIIWLVGTMGNIPRPQFREIASQGGNIDVLVSALGGILKSSSMDLLLTVF
                     SNFAVASSFLGVTLGLFDYLADLFKFNDSRLGRAKTAAITFLPPILGGLIYPDGFIYAI
                     GYAGLAATVWAAIVPALLARASRKRFGSPLYRVWGGTPMIVLILLFGAINAIAH"
     aSDomain        20785..21927
                     /aSDomain="TIGR00837"
                     /aSTool="tigrfam"
                     /description="araaP: aromatic amino acid transport protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3392_0049"
                     /evalue="5.00E-157"
                     /identifier="TIGR00837"
                     /label="ctg1_3392"
                     /locus_tag="ctg1_3392"
                     /protein_end="402"
                     /protein_start="21"
                     /score="521.0"
                     /tool="antismash"
                     /translation="GGAMIIAGTIVGAGMFSLPVVMSGIWFYWSIAVLVFTWFCMLHSG
                     LMILEANLNYHTGASFDTITKDLLGNGWNVINGLTVAFVLYILTYAYISASGSVIQHTL
                     RGMGIDFPARLGGLFFALFVAFIVWLSTTAVSRMTTIVLGAKILTFFMTFGGLLGHVEP
                     VKLFNLSDANPSYLPYLLMTLPFCLASFGYHGNVPSLMKYYGKNPHRIRNCLLFGTLLA
                     LALYIIWLVGTMGNIPRPQFREIASQGGNIDVLVSALGGILKSSSMDLLLTVFSNFAVA
                     SSFLGVTLGLFDYLADLFKFNDSRLGRAKTAAITFLPPILGGLIYPDGFIYAIGYAGLA
                     ATVWAAIVPALLARASRKRFGSPLYRVWGGTPMIVLILLFG"
     CDS             complement(22011..23192)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 73.5; E-value: 1.9e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3393"
                     /transl_table=11
                     /translation="MKSALTFSRRINPVFLAFFVVAFLSGIAGALQAPTLSLFLSTEVK
                     VRPLWVGLFYTVNAIAGITVSFVLAKRSDARGDRRKLIMVCYLMAVGNCLLFAFNRDYL
                     TLITAGVLLASVANTAMPQIFALAREYADSSAREVVMFSSIMRAQLSLAWVIGPPLSFM
                     LALNYGFTLMFSIAAGIFVLSALVVWFILPSVKRAEPVVDAPVVAQGSLFADKDVLLLF
                     IASMLMWTCNTMYIIDMPLYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGK
                     RKIMLFAVLAGVLFYTGLVLFKFKTALMLLQIFNAIFIGIVAGIGMLYFQDLMPGRAGA
                     ATTLFTNSISTGVILAGVLQGVLTETWGHNSVYVMAMILAILSLIICARVREA"
     aSDomain        complement(22020..23144)
                     /aSDomain="TIGR00899"
                     /aSTool="tigrfam"
                     /description="2A0120: sugar efflux transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3393_0050"
                     /evalue="5.70E-160"
                     /identifier="TIGR00899"
                     /label="ctg1_3393"
                     /locus_tag="ctg1_3393"
                     /protein_end="391"
                     /protein_start="16"
                     /score="530.4"
                     /tool="antismash"
                     /translation="AFFVVAFLSGIAGALQAPTLSLFLSTEVKVRPLWVGLFYTVNAIA
                     GITVSFVLAKRSDARGDRRKLIMVCYLMAVGNCLLFAFNRDYLTLITAGVLLASVANTA
                     MPQIFALAREYADSSAREVVMFSSIMRAQLSLAWVIGPPLSFMLALNYGFTLMFSIAAG
                     IFVLSALVVWFILPSVKRAEPVVDAPVVAQGSLFADKDVLLLFIASMLMWTCNTMYIID
                     MPLYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGKRKIMLFAVLAGVLFYT
                     GLVLFKFKTALMLLQIFNAIFIGIVAGIGMLYFQDLMPGRAGAATTLFTNSISTGVILA
                     GVLQGVLTETWGHNSVYVMAMILAILSLIICARVR"
     PFAM_domain     complement(22128..23138)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3393_0133"
                     /evalue="2.70E-31"
                     /label="ctg1_3393"
                     /locus_tag="ctg1_3393"
                     /protein_end="355"
                     /protein_start="18"
                     /score="108.9"
                     /tool="antismash"
                     /translation="FVVAFLSGIAGALQAPTLSLFLSTEVKVRPLWVGLFYTVNAIAGI
                     TVSFVLAKRSDARGDRRKLIMVCYLMAVGNCLLFAFNRDYLTLITAGVLLASVANTAMP
                     QIFALAREYADSSAREVVMFSSIMRAQLSLAWVIGPPLSFMLALNYGFTLMFSIAAGIF
                     VLSALVVWFILPSVKRAEPVVDAPVVAQGSLFADKDVLLLFIASMLMWTCNTMYIIDMP
                     LYITANLGLPERLAGLLMGTAAGLEIPIMLLAGYSVRRFGKRKIMLFAVLAGVLFYTGL
                     VLFKFKTALMLLQIFNAIFIGIVAGIGMLYFQDLMPGRAGAATTLFTNSISTGVIL"
ORIGIN
        1 tacaatgtaa acgcgccgcc gccagtgctt tttccaatgc atccggtgtg tgggcataat
       61 ccaccactac cgtcggttta cccggtgcat taaatacttc catccgccca cacactggtt
      121 gtagatgagg tgcggcagct aataattgtg ttagtgggta acccagtgaa agcagtgttg
      181 ccagtgccac cagcaagtta ctgacgttga atgcccccat caggcggctt tctaactggc
      241 cttcgcccca gcttgagtca aaagcaatgc tggcaccatt atcgtgatag tgaacctgag
      301 tggcagatag ccatgggcca ttccaaccca caggaatatt gccttccata ctaacggcga
      361 cagcttgcgg caactgccct aaccagcgac gaccgacttc gtcatcagca ttaatgattt
      421 tgtgttcgga ctgatgggtg gagaacaaca gccattttgc tgcttcgtaa ctcgccatat
      481 tgccgtgata atccagatga tcacgactta agttagtgaa cactgcagca gcaaacggca
      541 atgcggctac gcggttctga atcaaaccgt gagaggagac ttccatcgcg gcaaaagtcg
      601 ccccttggtc agccagattg cggagcaaat gctggatatc aaccgctgag ccggtggtgt
      661 tctcagtcgg gataacctgg cctagcagac cattgccaac cgtccccatc actgcactgg
      721 tttcgcccaa catttgagcc cattgcgcca gcaattgagt ggtggtggtt ttaccattgg
      781 ttccggtcac accgaccaaa cgtaatgcgg cacccggctg atggtaaaat tgtcccgcca
      841 gcttggataa gtgctgattc aaattacgca gatatataac aggaacacca tgcatctcga
      901 ccatactggc atccggtgcc acgccatcag cttcagcaac cacggccgcc acaccttgag
      961 cgatggcttg cgggatatag cgacgcccgt ccgtctggtg gccgacaata gcgacaaata
     1021 aatccccggc agcggcaaca cggctgtcta atgtcatttc ccgtagcgca cgctccggga
     1081 cgtctagccc ccaaggagcg agtaagtcgc gcaaattacg atctgccacc tgaaccctct
     1141 tttgtattag tcactaattc gcttttatca ccagtgggta atgcatctgg ctcaatgttc
     1201 atggtgcgca gtacaccgcc catgatggca ccgaacaccg gtgcagaaac cgcaccaccg
     1261 taatatttcc ctgcctgcgg gtcattgatg accacaacca gagcaaatct agggttactc
     1321 gcgggcgcga cgccagcggt gtaagcgaga tatcggtcca tatatttgcc atctgggccg
     1381 actttcttgg cggtaccggt tttaatggca attcggtagc ctttgattgc cgctttggtg
     1441 cccccgccgc caggtaatgc cacgctttcc atcatatgaa ccacggtacg caccagcggt
     1501 tcagggaaga cgcgttcacc ggccacaggc gggtcaactt tagtaatcga cagcgggcga
     1561 taaatcccca tgctgccaat ggttgcatag actcgcgcta gctgtaacgg tgttaccatt
     1621 agcccgtagc cgaaagagaa ggtggccctc tctatgtcag accaccgttg ttttttagga
     1681 tataagccac tgctttctcc gaccaacccc aaattggtcg ctttcccaaa cccaaacttt
     1741 gagtaagttt ctactaaagc tgaggatggc atcgctaacg ccagtttaga aacaccgacg
     1801 ttactcgact tctgcaagat cccggtcacg gatagctcgg cataacgggc cacgtcttta
     1861 atctggtgac cgttaacgaa gtacggcaag gtattcagca cgctgttctc tttcacaacg
     1921 ccatgctgca atgccgtcat cactaccatt ggctttactg tcgagccggg ttcaaaaata
     1981 tcggtaattg cccggttacg cattgcatct ttcggcgtac cggtgaggtt attcgggtta
     2041 taggatgggc tgttcgccat cgccaacact tcgccggtat tcacatccac cagcactgcg
     2101 gtccccgact ctgctttgtt gaatgccact gcattgttca gctcgcggta taccaacgcc
     2161 tgcaagcgct catcaacact caacaccaga ttgtgtgccg cttgactgtc cacggaggaa
     2221 atatcctcga taacgcggcc atagcggtct ttacgtaccg tgcgttcgcc cggctgcccg
     2281 gtaagccagc ggtcaaaact tttttctaca ccttcaatac cttggctatc gatgttagtt
     2341 acaccgatga tatgtgccat cacttgtcca gccggatagt aacggcggga ttcttgacgc
     2401 aaatagattc cgggtaattt cagcttatgg atgtagtcgc caattgccgg attgacctgg
     2461 cgagccagat aaacaaagcg ccctttcggg ttagcgttaa tgcgcgtcgc cagttgatct
     2521 aatgggattt ccaaagcatc agacagggct ttccagcggg tatcgagagt aatgccaccg
     2581 cgttcagtca actctttggg atcggcccaa acagcgttaa caggcacact gaccgccagt
     2641 ggtcggccag agcgatcact tatcatgcca cgcgcagtag ggacttcctg tacccgcaat
     2701 gagcgcatat cgccctcgcg caccagctta tcgggattaa tcacttgcag ataagcagta
     2761 cgcaacatca agccgaccaa tgccagcaaa atacagccgc acagcaacgc aaaacgccag
     2821 cttataaagc tggcttgttc ttcctggcgc tttaacttcc cggggcgcgc tgctttcatg
     2881 cgttaccttg gctactcaga gtcatggtgg cgacaaattc ctttatttat tggaaaaacc
     2941 tattgctgaa ccacaatatt ttcttgcgat ggatcaacat gttgcattct tagcttatcg
     3001 gttgcgatac tttcaacacg gctgtggtca cccaatgcgt tttcttccag aatcaagttg
     3061 cgccattcaa tatccagcgc atcccgttcc agtaccaact gttcgcgctc tgcggtcagc
     3121 aagcgcgtgc ggtgggcggt ggtcacaaca aaaatggcag ataccaacac cgcaatcagt
     3181 aggattaacg ggatcttcgc attgcggagt aaatccccgc cgatgactcc aactaaaccg
     3241 tggcgttcgt tgcctatcac tctttaatcc tctcggcaaa acgtaatacc gagctacgcg
     3301 cccgtgggtt ctcagccact tcagcatctg gcggcatcat tttgccgaca gatttcaagg
     3361 tgcggccacc catgctgcgt aactgtgctt ccgtcaatgg caaacccgct ggaacctgtg
     3421 ggccgcggct atgatgacgg ataaagtttt tcacaatacg gtcttcaagg gagtggaagc
     3481 taatgacaga taaacgacct tctggtgcca aaacttcaag agcaccgtcg agtgcgcgct
     3541 ctatctcttc caattcgctg ttgatataga tgcggatagc ctggaagctg cgcgtcgcag
     3601 gatgtttatg tttttcgcgg aatgggctgg cattggcaat caaatccgcc agctctttgg
     3661 tgcgtgtcat cggttgagtg aggttacgct caacaatggc cttggctaaa cgtttggcaa
     3721 aacgctcttc accgaaggtt ttcagcaccc aagcgatatc gtcagcactg gctttcatta
     3781 accactcggc tgccgatatg ccacgagtag ggtccatgcg catatccaac ggcccatcgc
     3841 gcatgaagga aaagccgcgc tcaggatcat ctaattgggg agaggagacg cccagatcca
     3901 gcaatacacc gttaatacgg ccgactaaat ccaattcccg cacataatgc gctaaatcag
     3961 aaaatgggcc gtgtacgata gaaaaacgtg ggtctgtaat ggatttcgct gcttcaatcg
     4021 cttgtgggtc acgatctatt gctatcaggc gcccttctgg cccaagttgg gacaaaatca
     4081 gacgcgagtg gccaccacgg ccaaaagttc cgtcaatata gatgccgtta tcacggatgt
     4141 tcaggccatt aaccgcctca tccagcaata cgcttgtgtg cttgtagttg ttatctacaa
     4201 tgtgattgtt atctaccatg cttatagcga taagtcctgt agccgctcag atagaggttc
     4261 ctgagtggac tgttctgcgt cgatgtcatc cttgacttgt tgataccagg tctgttcatc
     4321 ccacagttca aacttgttga actgcccaac cagcatcact tctttattca gcccggcgtg
     4381 ctgacgcaat gttcctgcaa tcagtaaacg cccagcgccg tccatctgac attcactggc
     4441 atgacctaac agcaaacgct gaactcggcg ttcagctggg ttcatgctcg acagccggga
     4501 taatttttgt tcaatgactt cccatgcagg gagtgtataa agcaacaggc atggttggtg
     4561 aaggtctatg gtacagacca tctggccttg cgattcctca ttcagcaaat cccggtaacg
     4621 ggtaggtacg gcaagccgcc ctttgctgtc gaggttaacc atcgttgccc cacgaaacat
     4681 gactgagtta ccccttcatg acccaattcg ccactttatc ccacaaatcc ccacattaaa
     4741 gagtttacgg atggtatgaa aaccttgtca agccagagca gatgcgcttt gacaaaattt
     4801 atgggccgtt tttgagatat atctcgtata aggggttatt ttcgcggttg gaatagaaat
     4861 taacatcatg ataaacgggc tatttttccg ccagtaattc cggcaactta aataaataat
     4921 aaattgtcaa ttaattgacg cattatttcc ttctgcaagg aatgtctcat ttttagtata
     4981 aaaattgtac ggtttgaaat tgcacacttt gagtacaaaa cccgcggcgg ctggcgtttc
     5041 ctaagaaaaa gcagtgcaac cagcagcaaa atcgacggta atacaataat acccttgata
     5101 acaacgagtg ttacccggca gacattttac ttcaattaac cgataaggat taatctattt
     5161 tgaaataaat tattagcgcc tatttttagg tattgatgaa atatgaatac cttcagacag
     5221 ataaatctta aattaggaaa agactgtaaa ttaatgttct ctctttcgtt tattttaaat
     5281 tttccgcctg atacacagtg tttctccgcc aaccactaaa attattaacc atatgttttt
     5341 aaacataaaa cacatgtaac accatttaaa aaaccacgaa aagcccaatt cctcgcagta
     5401 cgaagtataa aaaccagaca aatgttaaaa ataaaaattt taagctggtt atattaccag
     5461 caacagcact gtaaactaca caaaaagcaa aataacaata caatcacctg caatttaaat
     5521 aatgagcaat acataaaacc taccattaac ttcagagatg gaggtttcga cagatttttc
     5581 ccccaattag ggagttaatg acaatgtttt caactgggtc ccgtctgcgt agtgccgcag
     5641 ccgatacttt tgcacttgtg gtgtattgtt ttgtcatcgg catgatgatt gaaatagtga
     5701 tctctggaat gacattccag cagtcgctct cttcccgact ggtctcaatt cctgtcaaca
     5761 ttctgattgc ctggccctac ggcgtgtatc gtgatgcgtt cattcgtttt gcacgtcgcc
     5821 atgcaggcga acatatgtgg gcgagaaacc ttgccgactt actggcttat gtcagcttcc
     5881 agtcgccagt ctatgcctta attctgtggt ctgttggtgc agatttagaa cagataacca
     5941 cggcggtcgc gagtaacgcc ttggtctcaa tggctatggg tgtggcttat ggctattttt
     6001 tggagtactg ccgcaagctg tttcgcgtcg cagggtatgt ttgattgtta tgacttgcaa
     6061 tcagggcctc gaatgagccc tgattggcta aagcgtagac tatttgcgac ttaagctacc
     6121 gcggcggaac aaattgcggc gaatacgtgt taaccccggt tttggcttat gcggctcatc
     6181 cagactggct aatactaact ccagcacacg ttcagcgaca tcgcggtgac gttgtgctac
     6241 tgccaatact gggcattcga ggaaatccaa cagctcatta tcgccaaaag tggcaatagt
     6301 aagattactg ggtagacgtc cactttgttt taaagtgaca tccataacgc cctgcaatag
     6361 ctggaatgag gtggtaaaca gcgcttgcgg catgggatgg gtcttcagcc actgcgcaaa
     6421 cagcgtgcca gcagcttcgc gctcataact gttggcatac aggtaatcaa ccttacgcgg
     6481 atcgtctttc cacgcctcac ggaaccccat ctcccgcagg aaactgaccg acagttctgg
     6541 caacgcgccc agatacaata ctgattctgc cgggaatgaa cgcagttctt gtgccaacat
     6601 ctgcgcatct tcttgatctg caccgacaac actaatgaaa tgctcccgat caagcgcacg
     6661 atcgagtgcg attatcggta atggatcatt tgcccagcgc tgataaaaag ggtgctcagg
     6721 tggcagagcg gtagaaacga taatggcgtc aacctggcgc tgtaacaagt gctcgatgca
     6781 gcgcatttca ttatcaggct ggtcctcaga acaagcgatc aggagctgat aaccccgctg
     6841 gcgagcctga cgttccaaat aattcgcgat acgggtatag ctggtattct ccagatccgg
     6901 gataaccaaa ccaattgaac gagttctgcc cgcgcgcaac cctgctgcaa cagcatttgg
     6961 gtgatagtta tgttccctga caaccgccat aactttgtcg actgttttat cgctgacccg
     7021 atactgtttc gctttgccat taatgacata actggccgta gtgcgcgaaa cacctgcaag
     7081 gcgcgcgatt tcatccagtt tcacatagac cccttataaa ccctgtaaag taatattgta
     7141 ggctagacta agaagtctat agacatagtt taaccatgga tatgatctaa cagcagaact
     7201 cactattgag caaccgcttt aaccgccata taacgctatt ccgattaaaa aataagaaaa
     7261 aaaaagccca gcctactggc tgagcctgat aattggagat tagtcagtat taatcaccat
     7321 aattaaatta acgcatgatc ttgtcaccgc gagaaacacc gacaataccg gagcgagcaa
     7381 cttcaacaat ttctgccact tcccgcaccg catttaaaaa tgcgtccaat ttgtcgctgg
     7441 taccagcaag ctgcacggtg tagagcgttg cggtaacatc cacaatctgc cctcggaaga
     7501 tttcagcaca gcgcttcact tcttcacgcc cgtaaccgct agcctgcaat ttcaccagca
     7561 tgatttcgcg ctcaacatgt gagccagaaa ccaactcact cacacgcaac acatcgacca
     7621 atttatgcag ctgtttttca atctgctcca aaaccttggc atcacccact gtttggatgg
     7681 tcattctcga cagagttgga tcatcggtcg gtgcaaccgt caaactttca atgttataac
     7741 cgcgctgaga aaacaggccc accactcttg ataaggcacc tgactcgttt tccagcaaaa
     7801 ctgataaaat ccggcggcgc ataattatgt cctctccgtt ttactaagcc acatttcgtc
     7861 catgccaccg ccgcgaatct gcatcggata aacatgttct gtttcatcga cagttacatc
     7921 cacaaatacc agacgattag tctcggataa ttgtgtcaaa gcatcggcca gtttactttc
     7981 caactcatca ggagtgcgga tagaaacacc aatatgacca tatgcttcgg ccaatttgac
     8041 gaaatcaggt agagaatcca tgtaagactg tgaatgtcga ccagaataga tcatatcctg
     8101 ccactgcttc accatgccaa gataacggtt gttcaggttc aagaccaata ccggcaagtt
     8161 gtattgcaga gcggtagata attcctgaat attcatttgg atactgccat caccggtaac
     8221 acataccaca gtttcatccg gtagagccag tttcacccca agggccgctg gcagaccaaa
     8281 gcccatagta cccaggccac ctgagttgat ccaatggcgt ggtttatcaa atggatagta
     8341 gagtgcggca aacatttggt gctggccgac atcagaggtg acataggcat cacctttggt
     8401 caggcggtgt agtgtttcaa tcaccgcctg cggcttgatt tttccactgt ctttggcgta
     8461 actcaggcaa tcacgggcac gccactgttc aatggattgc caccaatcac gcaaactatc
     8521 aaaatcttgg gcgcaatcaa tttgaggcaa caagtccagc atttgtgtca gaacttgttt
     8581 ggcatcacca acaatcggaa tatcagcttc cacggttttt gatatggacg tcgggtcaat
     8641 atcaatgtgt accacagccg cattcgggca atatttcgcc agattattgg tggtacggtc
     8701 atcaaagcgc acgccaacgg caaaaatcag atccgtattg tgcatcgcca tgttggcctc
     8761 aaacgtcccg tgcatcccca acatacctac actttggcga tgtgtgccag ggaagctccc
     8821 taatcccatc agagagctgg tgaccggcaa attaagcttt tcagccaaag tcagtaactc
     8881 ttcatggcaa gctgagttaa tggccccgcc gccgacatac atgataggtc ttttagccgc
     8941 taaaatagtt tgcagtgcgc gtttaatctg cccgcgatgg ccttgcaccg tcggattata
     9001 agagcgcaaa ctgacttgtt cagggtaggc ataaggcatt ttcaccgctg ggccgacgat
     9061 atcttttggt agatcaataa ctaccgggcc agggcggcct gtcgatgcca gataaaacgc
     9121 ttttttcaat acggttggaa tatcttcagt acgtttaacc aggaagctgt gtttgacgac
     9181 gggccgggag atccccacca tgtcacattc ctggaaagca tcaaagccaa tcaatgagct
     9241 aggtacctgg ccagaaagca ccaccatcgg cactgaatcc atatacgccg ttgcaatgcc
     9301 ggttatggca ttggtcgcac cggggccaga tgtgactagc actaccccga cctcacctgt
     9361 ggcacgcgca taaccatcgg ccatatgaac cgcaccttgt tcgtggcgca ccagcacgtg
     9421 atcaatgcct ccgaccgtgt gcagggcatc gtagatatca agtacggccc cgccgggata
     9481 accgaataca tgcttaacgc cctgatcgat taacgatcgg acaaccatct cggctcctga
     9541 caacatctcc atgggttttg cctccaggct tagtttgctc attggataac gggaaatcat
     9601 ttccacgaaa tccggtagga aaggcacaac gccctgtatt cctatctttg tttgttatag
     9661 ttctaatgtt tattaacata actaacttat taacataacg tcagaatttc tggcaggcaa
     9721 acagcaatta tctgtgttaa aggcaattgt gttggtcaca aactggattt ttcttcatca
     9781 ggaaaataaa acactgcctg agctcccaca aacttgtttt tcgcgccgac ttactcatta
     9841 atcaaagaac taaatcaggc tgagaatttt tgcacatcag gtgcagcaaa atagtcacta
     9901 cgcgcaaaga gagaggagaa gagagacgtg tggtcagaaa gtcagcaacg gccgctatca
     9961 tcagacagat atcggccgtt acagtgaaaa tgatgctgga tcagtcgcgg tacatggagt
    10021 caatttcatt ctgataacgc tgaagaatga ttttacgccg taatttcatg gtcggagtca
    10081 attcaccggt ctccatcgtg aaggcctgcg gcaacagagt aaaacgctta acttgttcaa
    10141 actttgccaa ctctttttgc atatctttca gccgttgctc aaacaaactg acaatatggc
    10201 tatggcgcaa cagttctaat ctgtcatggt atttcaggtt tatcgaatga gcatattctt
    10261 ccagtgattc gaaacacgga acaatcagcg ccgaaacaaa tttgcgggta tcggcaataa
    10321 tagcaatctg ctcgataaat cgatcctggc ccaaggtgcc ttcaatcatc tgcggcgcaa
    10381 tatattttcc accggaagtt ttcatcaaat ctttcagccg ttcagtgatg aataaattcc
    10441 cctgaggatc taatgcgccg gcatcacctg ttttgagcca tccatcttcc gtaaaagact
    10501 ccgccgtctc ttggggttta ttgaaatagc cgcgcatcac aatcggaccg cgcacctgaa
    10561 tttcattttc agcgcccaga cgcacctcga tccccggtaa tggcttaccg atagagccaa
    10621 aacggaaatc tttttcttcc caacaagaaa cggtggcgca ggtctctgtc atgccatagc
    10681 cgtatttgat attgatacca attgcctgga aaaacagaat gatattatca tccagtcgag
    10741 cacctgcggc cggtaaaaag cgaactttcc cacccagaac accgcgcaat ttactcaaga
    10801 ctaaacgatc tgccagctta tacatctgct cagagaacca cgatgaggtt tgcccacttt
    10861 gcaaattttg gaatttgcgc tcgccacatc ctaccgccca gcggaataac atccggcgat
    10921 gccatttcgc cagagcaact ttgtcattaa tggcactaaa cactttctcg tagaaacggg
    10981 gaaccgcaca catgacggtc ggttttactg cctgcatcgc tgcgcgtacc caattagtgt
    11041 cactgatata cacattttgc gcgccagtat gcatgacata aaaactccag gcccgctcaa
    11101 acacatggga cagcggcaag aagctaagag aagtatcgtc agatgtcaga gtcaaacgtt
    11161 ggtcatgtaa gtagagctga gccgccatat ttcggtactc cagcatcaca cctttcggtt
    11221 cccccgtggt acctgaggta tagatcaagg tgaataagtc acttaaatcg caaccgtcta
    11281 tacgcgcgct taatagatgc tgttgtacgg catctggttg ttgttcaaaa tcagccaaat
    11341 gttgagcata ttcgcaacca cgtaaatcaa caccaggatc taatacaaca atatggctaa
    11401 gctgcggaca cagcggcttg agtgtgatcg caacgtcaaa ttgtgcttgt ccaccgacaa
    11461 acaaaatacg cacatcagca tcattcacta cataagccgc ttgagccgtt gtattggtgg
    11521 catacaacgg cacactcacg ccacgaatct gtaaaatagc taaatccgcc aatgaccatg
    11581 ccatgctgtt attagcaaaa atcccaatac gctcttggat ggcagcgccc aaggacaaca
    11641 aagccgcaga gatccgcgtt acgtgcgcat caatctgccg ccaggtcagc tgattttcgc
    11701 cttctggcga ccattcacga aaggcgactt tgtcggttct ctggcttatt tgttggcgca
    11761 aacggcgcac aaggtggtat tgatctaata tttgggtcat aaacgtcgca gctcgctggg
    11821 aaatcattcg ttaaagtgta ccgccacttt ttgcctgtta gctttcagct tacatgcgtt
    11881 cacttttttt cgcgcagtct actcactcta taggctatgg caaataaaat tcggcacaga
    11941 agtgtgagct gaaatcgatt ttgacgaaaa atacagcagt cagagtcatg gagagggaat
    12001 taaagcggat aaaagtattt ggctggatta gatcataatt aaacaccaga aataatgatg
    12061 ttaaaggtaa ctgcggtcct tgcctgccac tgagaataag acaactccag cagcaggact
    12121 taacgataat aattaagaag gaatactaag ctggctgagt agttctttca tccactgatg
    12181 tcctttatct ctatccgttg attcatgcca ggtgaggtaa catgggcgac atgtttcttc
    12241 ccaaggtaag gaaatcagtt tcagattaag cgcttcactg tatgtttgaa ccaaccagcg
    12301 aggagcaatg gcgacaaaac tagtttgaga tacaatattc agcacactgt tcatatcagt
    12361 actttcataa gcaatagttt tagtgctaat agctgattca taataaagtt ggctgaaaga
    12421 acccacttta tccaatgaga caatcgcatg taattcagaa aggagttgtt cttgcgtaat
    12481 tgaattatca atacgtgggt gatttttaga tacagctaaa actaattcat cattggataa
    12541 tgagacatgg tgaaaatcgg aacgttcgaa tttggtataa cctatcacaa actctgtttc
    12601 ttgataacgt aattgatgct caatattctc attaaggtga atcgccacgg ataatctaga
    12661 cacttccgag ccgttgataa tactggtttt catattctgt cggtgacatc tgatnnnnnn
    12721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnncttacc gctcatgggc acctctcttt
    12841 aagccatctt aaatgactct gaggtgtctg ttaaacccat ggcgattcaa aatatctttg
    12901 aacacttatc attaatgata ccaatattct ctttaatacc tcaacgaggt agaatcgagt
    12961 ctcatccttg tataagtgcg aaaacataaa tcacacctaa tgcatttggt gatcagtaaa
    13021 tatccatagg catacatata aacaatgaac acatgcaaaa tattttgcat ggtgaataaa
    13081 actaatctac attatcaata acaagacaac atcttgtcag cattaaaata taaccttgac
    13141 atgatcacat cacaaaatga gaacattaac aactatggca ttaatgaata ataaattctc
    13201 cacttataac ttattaatcc ttaattgatc ttaaaaagac aataatagcg aggagttttg
    13261 acattgatct agttataatt aatataaata gtcataaaat ataagaggca tgaaccaatt
    13321 cagattataa gataaaatat aatacatata aatatcttac ctatataaat aaaaaataag
    13381 atcccctgct gttggattat ttgattatta acttattacg tttaacactt ctctgcgcag
    13441 ctattcctta acgcggtttt taacattcca tagtctgaga gtaaatagcc catccgttca
    13501 taaaatcgta aagagaacaa taatccataa tcttggcgtt ataccaaaca aagtaaaaaa
    13561 aatatcttgg atttttagat gataaaactt aaaagtttaa cttttaggtt ttatatgtcg
    13621 ttataaggaa tttagagtcc gtgtaaccag ttgaacacgc cattttaaac aaatgttgac
    13681 acaaccatag aattcacgta tcaatttatg caacgcaata ttttaactaa tgagaaactg
    13741 aaaaattatg ttctactcaa cccgtctact aagcctacta cttaacgcat ctcccttgcg
    13801 cggtatgttg gtggacggaa atcagaactg attcagtcat caagattaac aagcccgcgc
    13861 aaatgcgcgg gttttttttt acccgctaag cgcaaaagta aacacgacaa ggaataaccc
    13921 atgagccaac aagtcattat tttcgataca accttgcgcg acggtgaaca agcattgcaa
    13981 gccagcctga gtgtaaaaga gaagctgcaa atcgcgttag cactggaaag gatgggtgtt
    14041 gatgtcatgg aagttgggtt cccggtttcc tcacctggcg attttgaatc cgttcgtact
    14101 atcgcgcagc aagtaaaaaa tagccgggtt tgtgctttgg cccgctgtgt agataaagat
    14161 atagatgttg ccgcagaagc tttgcgtatt gccgaggcat tccgtatcca cgtgtttttg
    14221 gcgacctcta ccttacatat tgaatccaag ttaaagcgct cgtttgatga tgtgttggcg
    14281 atggcggtac attcagtgaa acgcgcccgc aactataccg atgacgtaga attctcttgc
    14341 gaagatgcag gccgtacccc aattgacaac ttgtgccgta tcgtagaagc cgcaatcaat
    14401 gccggtgcta ctaccatcaa tattcctgat accgttggct acaccacacc atatcaattc
    14461 ggtggcatca tcactgactt gtatcagcgt gtaccgaata ttgataaagc cattatctcg
    14521 gtccattgcc atgacgattt gggtatgtcg gttgctaact ccattaccgc agtgcaagcc
    14581 ggggcacgtc aggtcgaagg gactattaat ggtttgggtg aacgcgcagg taactgttca
    14641 ctggaagaag tgatcatggc cattaaagtg cgcgaaaaca tgttgggcgt acataccaat
    14701 attaatcatc aagaaattta ccgtaccagc caattggtca gtaaattatg caatatgcca
    14761 atacctgcaa acaaagctat tgtcggtagc aatgcattcg ctcactcctc cggtattcat
    14821 caggatggcg tgctgaaaaa tcgcgaaaac tacgaaatca tgaccccaca atccatcggt
    14881 ttgaaagaag tgcagttaaa cctgacttcc cgctctggtc gtgccgcagt gaagcaccgg
    14941 atggaagaaa tgggttatca ggacaaagat tacaatctgg attccttgta tgacgcgttc
    15001 ctgaagctgg cggataagaa aggccaagtt tttgattacg atttggaagc cctggcattc
    15061 atcaataagc agcaggaaga gccagagcat taccgtttgg actatttcag tgtgcagtct
    15121 ggttcgagtg tgatggcgac cgcatcagtg aaattggttt gtggtgaaga aatcaaatca
    15181 gaagccgcca ccggtaatgg cccggttgac gcagtgtatc aagccatcaa ccgcattacc
    15241 gactacccca ttgaactggt gaaatatcaa ctgtctgcca atggtcaggg taaagacgca
    15301 ttaggtcagg ttgatatcgt ggttgaccat aaaggtcgcc gcttccacgg tgtggggctg
    15361 gccacagata ttgtcgagtc atctgctaag gcgttggttc acgtattaaa taacatctgg
    15421 cgcgctcatc aggtagaaat cgagaagcag cgtctgcaac aaaataatca ggaaatggtg
    15481 tgaacatgac taagacttat catattgccg ttttacccgg agacggtatt ggccctgaag
    15541 taatggctca ggcgaataaa gtattggatg ctgtgcgcca gcgtttcggt atcaagattt
    15601 caaccagcgc ttatgatgtc ggcggcgcag ctatcgaccg tcatggcagc ccgttaccgc
    15661 cagcaacagt gagtggatgc gaacaagctg atgccatctt attcggctca gtgggcggcc
    15721 ctaaatggga acatttacca ccggcggagc aaccggaacg cggtgcactg ttaccgttac
    15781 gcaaacactt taaattattc agtaacttgc gccctgcacg tttgtatcag ggattagaag
    15841 atttctgccc attgcgcagt gatatcgcgg cgaaaggctt cgatattctg tgtgtgcgcg
    15901 aattaaccgg cggcatctat ttcggtcaac ccaaaggtcg tgaaggccag gggatgcatg
    15961 aacgagcctt tgataccgaa gtttatcatc gctttgaaat tgaacgtatt gctcgtattg
    16021 cgtttgaatc cgctcgcaaa cgcggtggca aagttacttc tattgataaa gccaatgtgt
    16081 tgcagagttc catcctgtgg cgtgaagtcg ttaccgccat tgcggcagac tacccggatg
    16141 ttgcgttgtc ccatatgtat attgataacg ccaccatgca gttaattaaa gatccatccc
    16201 agtttgacgt cttgctgtgt tctaacttgt ttggcgacat tttgtcagat gagtgcgcca
    16261 tgattaccgg ctctatgggc atgttgccct cggccagtct gaacgaacaa gggtttggct
    16321 tatacgaacc agctggcggt tctgcaccgg atatcgcggg caaaaacatt gccaacccca
    16381 tcgcgcaaat tctctcttta gccctgttgt tgcgctttag tttaggtaaa gacgatgcgg
    16441 cggcggctat cgaaaacgcc atcaatcagg cattggaaca aggttatcgc actgctgatt
    16501 tagccggtga tggcaaagca atcggcacca acgaaatggg cgatatcatt gctaagttcg
    16561 tggctgaggg ggtttaatat gagcaaaacg ttatatcaaa acaagacctt atatcaaaaa
    16621 ttgtatgatg cacatatcgt ttacgaagcg ccgaatgaaa ccccgctgtt gtatatcgat
    16681 cgccacttag tgcatgaagt cacatcgccg caggcctttg atggcttgcg cgccatgggt
    16741 cgcccggtgc gtcaaccggg taaaaccttt gccaccatgg atcacaacgt ttcgacacaa
    16801 accaaagata tcaatgccag tggtgaaatg gcccgcattc agatgcagga gttgatcaag
    16861 aactgtgctg aattcggcgt gtctttgtat gacttgaatc acccattcca aggcattgtc
    16921 catgttattg gcccagagca aggaatgaca ttgccgggaa tgacgattgt ttgtggtgac
    16981 tcccataccg cgacccacgg tgcatttggc tcattagcat ttggtatcgg tacctcagaa
    17041 gttgaacatg tgttggccac tcagacgctg aaacaaggtc gggccaaaac catgaaaatc
    17101 gaagtcaatg gtgaggtggg cccaggcatt accgccaaag atatcgtgtt agcaattatc
    17161 ggcaaaaccg gcagcgccgg tggtactggt catgtagtgg aattctgtgg cagcgcgatt
    17221 gaagcgctga gcatggaagg ccgcatgaca ttgtgcaata tggcaattga aatgggcgcc
    17281 aaagccggtt tagtcgcacc ggacgacacc acttttaact atctgaaagg ccgtcaattc
    17341 gccccgacgg gtaagcaatg ggaacaaggc gtggcctact ggcgcacctt gaaatctgat
    17401 gctgacgcta aatttgatac tgtggtgacc ttagatgccg ctgatatcgc gccacaagtg
    17461 acctggggta ccaatccggg tcaggtgatt gcggttaatc aaattattcc ggcacccgag
    17521 tcctttagtg atcctgttga gcgcgcttca gccgaaaaag ccttggctta tatggattta
    17581 cgccccggta tcaaattgac cgaagtcgcg attgataaag tctttatcgg ttcttgcact
    17641 aactcgcgta ttgaagattt acgtgccgca gccgcagtgg cgcaagggcg taaagtggcc
    17701 agcggtgtac aggcgattgt ggtgcccggc tccggcccgg tgaaagcaca agccgaagcg
    17761 gaaggtttgg ataaaatctt tatcgaagcc ggttttgagt ggcgtttacc cggctgctcc
    17821 atgtgtttgg cgatgaataa cgaccgtctg gaacccggcg agcgctgtgc atccaccagc
    17881 aaccgtaact ttgaagggcg tcagggccgt gggggtcgca cccatttggt tagcccggca
    17941 atggcagccg ccgctgcggt cagtggtcac tttgctgatg tccgcgactt atcagctgcc
    18001 acccactaat cggagatacc accatgacaa aatttactca acacactggt tttgctcaac
    18061 acactggttt tgctcaacat aggggcctgg tcgctccgtt ggatgcggcg aatgtcgata
    18121 ccgacgcgat tatcccgaaa cagtttttgc aaaaagtaac gcgcactggt tttggtcagc
    18181 acctgtttaa cgactggcgt tttctggacg atgctggcaa agtccctaac ccggaatttg
    18241 tactgaatca acctcgctat cagggtgcga ccattttatt agcgcgcgaa aatttcggct
    18301 gcggttcatc acgtgaacat gcaccttggg cactgacaga tttcggtttt aaagtggtta
    18361 ttgctccgag ctttgctgat attttttacg gcaattcatt taataaccaa ttattaccgg
    18421 taacattaag tgaaggtgat attgatactt tattccagct ggttaaagag aatgaaggta
    18481 tcgagtttat tgtcgattta gaacaccaaa cggtgaatgc cggagggaaa agttattctt
    18541 ttgaaattga tagtttccgt cgtcattgca tgattaacgg tttagacagc attggcctga
    18601 cattgcagca cgaaaacaat atttcagcat acgaaaaaca acagccagaa ttcctgcgtt
    18661 aattattttt agttcatttt gtgagtatat tgttggtgtc aggaagcccc tgacccaaca
    18721 attaaaaatc gataaaaatc ctaatcagaa aaatcattcc ccattcactt cccattgact
    18781 gtaaaaccca aacctcatat caatcatact gttatataac agcactgtaa cccattagat
    18841 tacataaata ttagtgcttc taatatagtt ttaattgatt gtaatttgtg ctgaatatca
    18901 ctttttattt tttaaacaac gctatgctgt tactcactat ccacacctag aggcgcctta
    18961 tgacacgcat tgcattgcgt taccaagcac gcatctccgg cgacagccga gcctggttta
    19021 atattgatta ccgccttgcc aacgatttcc cgcgttaatt cccccattgc ttattcagct
    19081 taggctgaaa aaactcattt ctttattttg ttgccgtcat aggtaatacg gatcgctatt
    19141 tttaatttta gccaatccta ttagccacgg tatatctata tccaaaaaaa atgatatttg
    19201 gagtaataag ccatgaaacg catccctgag cccttccgca ttaaaatggt cgaaaatatt
    19261 cggatgacca atcgggaagc tcgtgagaaa gcactgattg aagcgggcta taatccattc
    19321 ttattaccaa gtgaagatgt atatattgat ttactgactg actccggcac cggggcaatg
    19381 agtgatcgtc agtgggctgg cttaatgatg ggtgatgagg cctacgccgg ttcacgtaac
    19441 tattatcacc tgtgtgatca ggttaaaaaa ctgattggct acccatttac tatcccaaca
    19501 catcagggcc gtggcgctga acaaatccta ttcccttgcc tgattgcgaa aaaacaaaaa
    19561 gccggtggcg ccaagaaccc tgtctttatt tccaacttcc attttgatac caccgccgct
    19621 cacgttgaga tgaatggcgc taaagctatc aacgtcgtca ccccgaaagc ctttgatact
    19681 gtggcttatt atgactggaa aggtgacttc gatttagacc aattgaaagc aacaattgcc
    19741 gaatatggcg ctgacaacgt ggtgtcaatt attaccaccg tcacttgtaa cagctccggt
    19801 gggcagccaa tttcaatgag caatatgcgc gaagtgtatc gaattgctca acagcataat
    19861 attccggtgg tcatcgactc cgcccgcttc tgtgaaaatg cctggtttat caaacaacgc
    19921 gagccaggtt atggcgacaa gtcgatcaaa gagatcattc tggaaatgta tcaatacggc
    19981 gacatgctca ccatgtcagc caaaaaagac ccgatggtga atattggcgg tttgtgctgt
    20041 ttccgcaccg atgaagacct attcaacgat gttcgtatcc gttgcgtgcc gatggaaggt
    20101 tttgtcactt acggtggatt ggctggtcgc gacatggaag cgctggccat tgggctggag
    20161 gaagggatga atgaagactt cctgacatac cgtattgggc aggtagagta tcttggcgag
    20221 cggctgcgtg ctggcggtat tccgattcaa tatcctaccg gcggtcatgc ggtgtttgtc
    20281 gatgccaaaa tcctgctgcc tcatattcca gccgaacaat tcccggcaca ggctctaaat
    20341 aatgcgttgt atctggaagc aggtattcgc agtgtggaaa ttggatcatt gctgctaggc
    20401 cgtgatccac aaaccggtaa acaaaaacca tcgccattgg aactgctgcg cctgaccatc
    20461 ccgcgccgag tctataccaa tgaccatatg gattacattg ccgatgccct gatttcactc
    20521 aaatcacgtg ctgaagaaat caaaggctta accttcacct acgaaccccc tgttctgcgc
    20581 cactttgttg cccgattaaa acctatcgaa taagcggcaa ccaccatacc aagaccacgc
    20641 cccctgctgc tctggcaggg ggaaaacagc tacaaaatcg ctacctctat aagtggtaaa
    20701 accacacgag gacaccctac tatggcccaa actacactag aagatcaggt cacagcagca
    20761 aaaattaaaa acccttccct cctcggcggt gccatgatta ttgcaggcac tatcgtcggc
    20821 gcagggatgt tttcattacc cgttgtcatg tcagggatct ggttttattg gtctattgcg
    20881 gttctggttt ttacctggtt ttgcatgctt cactcaggat taatgatcct cgaagccaat
    20941 ctcaactatc ataccggtgc cagttttgac accatcacca aagacttact gggtaacggc
    21001 tggaatgtga taaatggcct gaccgtcgcc tttgttctct acattctgac ctacgcctat
    21061 atctctgcca gtggctcggt tattcagcat acgctacgcg gaatgggaat agacttccct
    21121 gcccgattgg gcggcctgtt ctttgcttta ttcgtcgctt ttattgtttg gctcagtacc
    21181 actgcggtga gccgaatgac cactatcgtg ctgggtgcca agatactcac gttctttatg
    21241 acattcggcg ggttgttagg ccatgtcgaa ccggtgaaat tgtttaatct gagtgacgcc
    21301 aacccaagct acctgcccta tctgttgatg acactgccat tttgtctggc gtcattcggt
    21361 tatcacggta atgtccccag tttgatgaag tattacggta aaaacccaca ccgtatccgc
    21421 aactgcttgc tatttggcac cttgctggca ctggcgctat atatcatctg gttggtcggt
    21481 actatgggga atattccacg accacaattt cgcgaaatag ccagtcaggg gggcaatatt
    21541 gatgtgctgg tcagtgcgtt aggcgggata ttaaaaagct cgtcaatgga cctgctgctg
    21601 acagtattct caaacttcgc cgtcgccagt tcattcctgg gcgtcacttt gggcttattc
    21661 gattatctag ctgatttatt taaatttaac gacagtcgtt tgggtcgggc aaaaacagct
    21721 gccatcacct tcctgccgcc aatattgggt gggttgattt atcccgatgg tttcatttac
    21781 gccatcggtt atgccggact agccgctacc gtctgggccg ccattgttcc tgcgctgctg
    21841 gcacgggcct cacgcaaacg ctttggtagc ccgctgtatc gcgtctgggg cggtaccccg
    21901 atgattgtat tgattttact attcggggcg attaatgcca tcgcccatat cctgtcgagt
    21961 ctgaacttgc tgcccgtcta ctaaaactcc acacagcgcc ctgcggggcg ctaagcttcc
    22021 ctcactcgcg cacaaataat aagcgataga atggcgagga tcatcgccat gacatacacc
    22081 gaattatggc cccaggtttc agttaatact ccttgcaata cccccgccag aatcacccca
    22141 gttgaaatac tgttggtaaa tagtgtggtg gcagctcccg ctctgcccgg cattaaatcc
    22201 tgaaaataaa gcatcccaat tccggcaaca ataccgatga aaatggcatt aaaaatctgc
    22261 aataacatca atgctgtttt aaatttaaat aacaccagcc cggtataaaa cagcacgcca
    22321 gccagcacgg cgaacagcat aattttacgc ttaccaaaac gcctgaccga ataccccgcc
    22381 agcagcataa taggaatttc cagcccagcc gccgttccca tcaataagcc ggccagccgc
    22441 tccggcagcc ccagattagc agtgatatat aacggcatat caatgatgta catggtgttg
    22501 catgtccaca tcaacattga ggcaataaac agcagcagga catctttatc ggcaaacagg
    22561 ctaccctgcg caaccacagg cgcatccacc accggctcgg ctcgcttcac cgacggcaaa
    22621 ataaaccaca ccaccagcgc actcagcaca aagatacccg cagcaatact gaacatcaga
    22681 gtaaagccat aattcagcgc cagcataaat gataatggcg gcccgataac ccacgccaat
    22741 gaaagctgcg cacgcataat tgagctaaac atcaccactt cgcgggctga gctatcggca
    22801 tattcacgcg ccagagcgaa aatctgtggc atggcggtat tagccaccga ggccaatagc
    22861 acaccggcgg tgatcaaggt gagataatca cgattaaaag caaacagcag gcagttcccc
    22921 accgccatca gatagcaaac cataatcagc ttgcggcgat cccccctagc atccgagcgc
    22981 ttggccaata caaagctgac ggtaatcccc gcgatagcat tcacggtata aaatagccca
    23041 acccacagcg ggcgcacttt cacttcggta cttaaaaata gacttaaggt gggagcctgc
    23101 aaagcgcctg caataccaga gagaaaagcc accacaaaga acgcaagaaa aaccgggttg
    23161 atacgacggg aaaaggttaa tgcagatttc attccaggct ccagcgccag aaacagcgag
    23221 tgaacgctat gctacagaag cgcgcagatt tatatagaga aaaatagata agccgcataa
    23281 atttacctcc agataattga taccgtgaat cttgtttcag caccaaaggc gcaggataaa
    23341 aaaagccagt ggcataaccc actggctggt gaaagacacc attactcaga aattttttgg
    23401 aactcaggac tacagcaaga ctcatcacta aaaaaacaat ttaaaacagt cgattacaaa
    23461 atgtgctctg tgcgggcgat aatatcgtcc tgcgcatccg gtgacagtgc ggtgaagaat
    23521 gccgagtaac ccgccaccct aaccactaag tcgcggtaac gatccggatg ttgcttggcc
    23581 tccaataagg tctcccgcga cacgatgttg tattgcacat gccaccccag atactcttca
    23641 aagaaggtgc gcaacatcat catcaacttt tcacggtcac gcgggttatc taatgtagat
    23701 ggattcaatt tttgattgag caacaccccg ccaagaatag aggcggtcgg taatttcgat
    23761 agcgagttaa acaccgccgt tggccccaga tggtcggtgc cagaagccgg gcttgcacct
    23821 tccgccaatg ggctgtgtgc tttacggcca tccggtgttg ccatggtcgc cgcgccaaag
    23881 ggcacattgg cagaaatgga tgacgtgccc gcataataag taccgccaat cgggccgcga
    23941 ccaaagcgag tattgtgata ttgcttcagc tcatcaatgt aagtctgata agcgcggact
    24001 aacagttgat caacatcatc aacatcattg ccatatttcg gcgctgaatt tatcaggtgc
    24061 tgacgcagtt gctcgccatt caaaccggta aaatcattgg ctaatgctgt agccagctgc
    24121 tgttggctga taagttgttg ttcaaatact aattttctca ccgccgccag actatttccc
    24181 aagttggcaa tcccgacttg caaaccagaa acccagtcat agcgcgcccc gccttgcttg
    24241 atgcttttgc cacgctcaat gcaatcatct accagcgcag aacagacaat atcgtgggcg
    24301 ttctcttcca ataccgtatc cactacacac tctatctcga tagatttgcg ggtgtagtaa
    24361 cgaatctgcg catcccattg cgtcatcact tgagagaaat cgctaaagtt gcccttcgac
    24421 aaaccttgct cttgcggcaa aaatacctgc ccggatgttg catctcggcc ctgctccagc
    24481 gccgccaaca tcactctggc aaagttaatg aaactcatgc cagtgcagcg gtaaccccac
    24541 ttgccgccaa ccgccgtttc aatacaacca attgccgcgt aatcataagc atcctgcggc
    24601 tcgacaccca gtttgataaa ttcgggaata acaatttcgt cattgttaaa cgctggcata
    24661 ccaaaaccgc agcgaataac ttgcacgcag gcatccagaa aatcatcact gataccggca
    24721 tggtaacgaa cactcaagtt tggctgagtg gagcgcaagc gcccgcatga ctccagtacc
    24781 gcataagaaa gtggattcac ggcatcaata gctttgccct gtaccagctt ttgcccaccg
    24841 atagtgacgt tttgataaag tgggctgccc gctgaagctt tggagtgcga tccggagcgg
    24901 attttattca cctccagcaa tttcagccaa cagctatgca gcatttcaat ggcttgttcg
    24961 cggctaaggg tgttttccag ttcaacatcg cggcgatacc aggggtacaa atattgatcc
    25021 agacgaccaa aggaaaccga gtgaccatta gattcaatct gcaaaatcaa ctgaatgaaa
    25081 tagcacaatt gcagcgcttg ccagaaagtc tgcggtggct gatgggcaat caattcacag
    25141 ttttcggcga tagtctgtag ctctatccga cgccattcgc gagtttcatc cagtgccatt
    25201 tgccgtgcca ctgcggcgta gcgctcaata tgttcgctta gagccgccag cgaaatatca
    25261 atcgctttca ggaattgttc tttatgcagg tcactccagt ccgtcagttg cagccgttca
    25321 cggcggctgg ccactttact gcgcaggcca tccagccctt tttccagcaa taacgggaag
    25381 ttaaccgcca aatgcgcatc accggaggtc atattcccct cggcttttat aatgccggtt
    25441 gccagcaagg ctttttgttc gtcggtgaac ataccatagc agc
//
