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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_JH594596.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | terpene | 422,152 | 442,991 |
Region 1.2 | lanthipeptide-class-i | 1,194,447 | 1,218,757 |
Region 1.3 | betalactone | 2,640,280 | 2,670,108 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | terpene | 422,152 | 442,991 |
Region 1.2 | lanthipeptide-class-i | 1,194,447 | 1,218,757 |
Region 1.3 | betalactone | 2,640,280 | 2,670,108 |

No secondary metabolite regions were found in these records:
  NZ_JH594597.1
  NZ_JH594598.1
  NZ_JH594599.1
  NZ_JH594600.1
  NZ_JH594601.1
  NZ_JH594602.1
  NZ_JH594603.1
  NZ_JH594604.1

Compact view
NZ_JH594596.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 422,152 - 442,991 nt. (total: 20,840 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.33 | Terpene | carotenoid | Myxococcus xanthus
BGC0000645.1 |  | 0.28 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000650.1 |  | 0.24 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000637.1 |  | 0.23 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000644.1 |  | 0.21 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000634.1 |  | 0.19 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000643.1 |  | 0.19 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0001514.1 |  | 0.19 | Other | aristeromycin | Streptomyces citricolor
BGC0000640.1 |  | 0.19 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000630.1 |  | 0.19 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.66 | Terpene | carotenoid | Myxococcus xanthus
BGC0000645.1 |  | 0.61 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000650.1 |  | 0.57 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000637.1 |  | 0.56 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000644.1 |  | 0.53 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000634.1 |  | 0.52 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000643.1 |  | 0.52 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0001514.1 |  | 0.51 | Other | aristeromycin | Streptomyces citricolor
BGC0000640.1 |  | 0.51 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000630.1 |  | 0.51 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_JH594596.1 - Region 2 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,194,447 - 1,218,757 nt. (total: 24,311 nt) Show pHMM detection rules used
lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-i | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001289.1 |  | 0.27 | RiPP | penisin | Paenibacillus ehimensis
BGC0000560.1 |  | 0.22 | RiPP | subtilomycin | Bacillus subtilis
BGC0000542.1 |  | 0.21 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000541.1 |  | 0.21 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0001727.1 |  | 0.20 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000536.1 |  | 0.19 | RiPP | nisin Q | Lactococcus lactis
BGC0000515.1 |  | 0.19 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0001789.1 |  | 0.19 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.19 | RiPP | nisin U | Streptococcus uberis
BGC0000506.1 |  | 0.18 | RiPP | entianin | Bacillus subtilis subsp. spizizenii

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001289.1 |  | 0.60 | RiPP | penisin | Paenibacillus ehimensis
BGC0000560.1 |  | 0.55 | RiPP | subtilomycin | Bacillus subtilis
BGC0000542.1 |  | 0.54 | RiPP | paenicidin B | Paenibacillus terrae
BGC0000541.1 |  | 0.54 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0001727.1 |  | 0.52 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000536.1 |  | 0.51 | RiPP | nisin Q | Lactococcus lactis
BGC0000515.1 |  | 0.51 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0001789.1 |  | 0.51 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.51 | RiPP | nisin U | Streptococcus uberis
BGC0000506.1 |  | 0.50 | RiPP | entianin | Bacillus subtilis subsp. spizizenii

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.
Lanthipeptides - No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.
NZ_JH594596.1 - Region 3 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,640,280 - 2,670,108 nt. (total: 29,829 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001514.1 |  | 0.18 | Other | aristeromycin | Streptomyces citricolor
BGC0001475.1 |  | 0.16 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0000666.1 |  | 0.15 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000665.1 |  | 0.15 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0001156.1 |  | 0.15 | Terpene | platencin | Streptomyces platensis
BGC0001140.1 |  | 0.15 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0001928.1 |  | 0.15 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001641.1 |  | 0.14 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001664.1 |  | 0.14 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0000805.1 |  | 0.13 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001514.1 |  | 0.50 | Other | aristeromycin | Streptomyces citricolor
BGC0001475.1 |  | 0.47 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0000666.1 |  | 0.45 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000665.1 |  | 0.45 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0001156.1 |  | 0.45 | Terpene | platencin | Streptomyces platensis
BGC0001140.1 |  | 0.45 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0001928.1 |  | 0.45 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001641.1 |  | 0.43 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001664.1 |  | 0.43 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0000805.1 |  | 0.42 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names