Select genomic region:
Overview
1.1
5.1
5.2

### Identified secondary metabolite regions using strictness 'relaxed'

c00001_NZ_CABK.. (original name was: NZ_CABKRN010000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 1,453,916 | 1,474,266 |

c00005_NZ_CABK.. (original name was: NZ_CABKRN010000005.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | arylpolyene | 294,931 | 342,430 | flexirubin | Other | 48%
Region 5.2 | RRE-containing | 711,186 | 731,452 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 1,453,916 | 1,474,266 |
Region 5.1 | arylpolyene | 294,931 | 342,430 | flexirubin | Other | 48%
Region 5.2 | RRE-containing | 711,186 | 731,452 |

No secondary metabolite regions were found in these records:
  c00002_NZ_CABK.. (original name was: NZ_CABKRN010000002.1)
  c00003_NZ_CABK.. (original name was: NZ_CABKRN010000003.1)
  c00004_NZ_CABK.. (original name was: NZ_CABKRN010000004.1)
  c00006_NZ_CABK.. (original name was: NZ_CABKRN010000006.1)
  c00007_NZ_CABK.. (original name was: NZ_CABKRN010000007.1)
  c00008_NZ_CABK.. (original name was: NZ_CABKRN010000008.1)
  c00009_NZ_CABK.. (original name was: NZ_CABKRN010000009.1)
  c00010_NZ_CABK.. (original name was: NZ_CABKRN010000010.1)
  c00011_NZ_CABK.. (original name was: NZ_CABKRN010000011.1)
  c00012_NZ_CABK.. (original name was: NZ_CABKRN010000012.1)
  c00013_NZ_CABK.. (original name was: NZ_CABKRN010000013.1)
  c00014_NZ_CABK.. (original name was: NZ_CABKRN010000014.1)
  c00015_NZ_CABK.. (original name was: NZ_CABKRN010000015.1)

Compact view
c00001_NZ_CABK.. - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,453,916 - 1,474,266 nt. (total: 20,351 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001588.1 |  | 0.17 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001589.1 |  | 0.17 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001120.1 |  | 0.16 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000905.1 |  | 0.14 | Other | heme D1 | Heliobacillus mobilis
BGC0000899.1 |  | 0.13 | Other | desosamine | Streptomyces narbonensis
BGC0000898.1 |  | 0.13 | Saccharide | desosamine | Streptomyces venezuelae
BGC0000906.1 |  | 0.13 | Other | heme D1 | Heliophilum fasciatum
BGC0001838.1 |  | 0.09 | NRP | WLIP | Pseudomonas putida
BGC0000045.1 |  | 0.08 | Polyketide | dehydrocurvularin | Aspergillus terreus
BGC0001657.1 |  | 0.07 | NRP | lysocin | Lysobacter sp. RH2180-5

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001588.1 |  | 0.48 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001589.1 |  | 0.48 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001120.1 |  | 0.47 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000905.1 |  | 0.43 | Other | heme D1 | Heliobacillus mobilis
BGC0000899.1 |  | 0.42 | Other | desosamine | Streptomyces narbonensis
BGC0000898.1 |  | 0.42 | Saccharide | desosamine | Streptomyces venezuelae
BGC0000906.1 |  | 0.41 | Other | heme D1 | Heliophilum fasciatum
BGC0001838.1 |  | 0.34 | NRP | WLIP | Pseudomonas putida
BGC0000045.1 |  | 0.31 | Polyketide | dehydrocurvularin | Aspergillus terreus
BGC0001657.1 |  | 0.30 | NRP | lysocin | Lysobacter sp. RH2180-5

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_CABK.. - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 294,931 - 342,430 nt. (total: 47,500 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.30 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0000231.1 |  | 0.23 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.22 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000838.1 |  | 0.22 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000228.1 |  | 0.21 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000248.1 |  | 0.20 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000194.1 |  | 0.20 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000219.1 |  | 0.20 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus
BGC0000509.1 |  | 0.20 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000261.1 |  | 0.19 | Polyketide | R1128 | Streptomyces sp. R1128

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.63 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0000231.1 |  | 0.56 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.55 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000838.1 |  | 0.55 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000228.1 |  | 0.54 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000248.1 |  | 0.53 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000194.1 |  | 0.53 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000219.1 |  | 0.52 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus
BGC0000509.1 |  | 0.52 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000261.1 |  | 0.52 | Polyketide | R1128 | Streptomyces sp. R1128

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_CABK.. - Region 2 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 711,186 - 731,452 nt. (total: 20,267 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.18 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0001655.1 |  | 0.17 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0000494.1 |  | 0.17 | RiPP | uberolysin | Streptococcus uberis
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000575.1 |  | 0.15 | RiPP | lariatin | Rhodococcus jostii
BGC0001549.1 |  | 0.15 | RiPP | citrulassin B | Streptomyces aurantiacus JA 4570
BGC0001634.1 |  | 0.15 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0001496.1 |  | 0.15 | RiPP | actinokineosin | Actinokineospora spheciospongiae
BGC0001552.1 |  | 0.15 | RiPP | citrulassin F | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000519.1 |  | 0.15 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.50 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0001655.1 |  | 0.48 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0000494.1 |  | 0.48 | RiPP | uberolysin | Streptococcus uberis
BGC0000554.1 |  | 0.46 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000575.1 |  | 0.46 | RiPP | lariatin | Rhodococcus jostii
BGC0001549.1 |  | 0.46 | RiPP | citrulassin B | Streptomyces aurantiacus JA 4570
BGC0001634.1 |  | 0.46 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0001496.1 |  | 0.46 | RiPP | actinokineosin | Actinokineospora spheciospongiae
BGC0001552.1 |  | 0.46 | RiPP | citrulassin F | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000519.1 |  | 0.46 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names