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Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
1.8

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_NJFR02000001 (original name was: NZ_NJFR02000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | thiopeptide | 679,944 | 706,378 |
Region 1.2 | terpene | 1,361,714 | 1,382,805 |
Region 1.3 | redox-cofactor | 1,392,825 | 1,414,990 | lankacidin C | NRP + Polyketide | 13%
Region 1.4 | NRPS | 2,451,922 | 2,495,866 | turnerbactin | NRP | 38%
Region 1.5 | hserlactone | 4,102,818 | 4,121,067 |
Region 1.6 | hserlactone | 4,122,457 | 4,142,999 |
Region 1.7 | betalactone | 4,732,746 | 4,758,406 |
Region 1.8 | arylpolyene,siderophore | 4,888,590 | 4,937,020 | APE Ec | Other | 84%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | thiopeptide | 679,944 | 706,378 |
Region 1.2 | terpene | 1,361,714 | 1,382,805 |
Region 1.3 | redox-cofactor | 1,392,825 | 1,414,990 | lankacidin C | NRP + Polyketide | 13%
Region 1.4 | NRPS | 2,451,922 | 2,495,866 | turnerbactin | NRP | 38%
Region 1.5 | hserlactone | 4,102,818 | 4,121,067 |
Region 1.6 | hserlactone | 4,122,457 | 4,142,999 |
Region 1.7 | betalactone | 4,732,746 | 4,758,406 |
Region 1.8 | arylpolyene,siderophore | 4,888,590 | 4,937,020 | APE Ec | Other | 84%

No secondary metabolite regions were found in these records:
  NZ_NJFR02000002 (original name was: NZ_NJFR02000002.1)
  NZ_NJFR02000003 (original name was: NZ_NJFR02000003.1)
  NZ_NJFR02000004 (original name was: NZ_NJFR02000004.1)
  NZ_NJFR02000005 (original name was: NZ_NJFR02000005.1)
  NZ_NJFR02000006 (original name was: NZ_NJFR02000006.1)

Compact view
c00001_NZ_NJFR.. - Region 1 - thiopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 679,944 - 706,378 nt. (total: 26,435 nt) Show pHMM detection rules used
thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Thiopeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | thiopeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001285.1 |  | 0.12 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001441.1 |  | 0.09 | Other | belactosin A, belactosin C | Streptomyces sp.

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001285.1 |  | 0.39 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001441.1 |  | 0.33 | Other | belactosin A, belactosin C | Streptomyces sp.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Thiopeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash. Predicted tail sequences are also shown.
No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Thiopeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
c00001_NZ_NJFR.. - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,361,714 - 1,382,805 nt. (total: 21,092 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.26 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.26 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.26 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.25 | Other | ectoine | Methylomicrobium kenyense
BGC0000852.1 |  | 0.25 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  | 0.25 | Other | ectoine | Methylobacter marinus
BGC0000853.1 |  | 0.25 | Other | ectoine | Streptomyces anulatus
BGC0000856.1 |  | 0.25 | Other | ectoine | Methylophaga thalassica
BGC0000860.1 |  | 0.25 | Other | ectoine | Methylarcula marina
BGC0000664.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.59 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.59 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.59 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.59 | Other | ectoine | Methylomicrobium kenyense
BGC0000852.1 |  | 0.59 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  | 0.59 | Other | ectoine | Methylobacter marinus
BGC0000853.1 |  | 0.59 | Other | ectoine | Streptomyces anulatus
BGC0000856.1 |  | 0.58 | Other | ectoine | Methylophaga thalassica
BGC0000860.1 |  | 0.58 | Other | ectoine | Methylarcula marina
BGC0000664.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_NJFR.. - Region 3 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,392,825 - 1,414,990 nt. (total: 22,166 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000905.1 |  | 0.13 | Other | heme D1 | Heliobacillus mobilis
BGC0000320.1 |  | 0.12 | NRP | cereulide | Bacillus cereus
BGC0000297.1 |  | 0.11 | NRP, Polyketide, Saccharide | aeruginoside 126B, aeruginoside 126A | Planktothrix agardhii NIVA-CYA 126
BGC0001365.1 |  | 0.09 | NRP | clapurines | Claviceps purpurea 20.1
BGC0000321.1 |  | 0.09 | NRP | chaetocin | Collariella virescens
BGC0001100.1 |  | 0.09 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001212.1 |  | 0.08 | NRP, Polyketide | nannocystin a | Nannocystis sp. MB1016
BGC0000292.1 |  | 0.08 | NRP | acetylaranotin | Aspergillus terreus NIH2624
BGC0001656.1 |  | 0.08 | Polyketide | luminaolide | Planktothrix paucivesiculata PCC 9631
BGC0000361.1 |  | 0.08 | NRP | gliotoxin, bisdethiobis(methylthio)gliotoxin | Aspergillus fumigatus Af293

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000905.1 |  | 0.41 | Other | heme D1 | Heliobacillus mobilis
BGC0000320.1 |  | 0.39 | NRP | cereulide | Bacillus cereus
BGC0000297.1 |  | 0.38 | NRP, Polyketide, Saccharide | aeruginoside 126B, aeruginoside 126A | Planktothrix agardhii NIVA-CYA 126
BGC0001365.1 |  | 0.34 | NRP | clapurines | Claviceps purpurea 20.1
BGC0000321.1 |  | 0.33 | NRP | chaetocin | Collariella virescens
BGC0001100.1 |  | 0.33 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001212.1 |  | 0.32 | NRP, Polyketide | nannocystin a | Nannocystis sp. MB1016
BGC0000292.1 |  | 0.32 | NRP | acetylaranotin | Aspergillus terreus NIH2624
BGC0001656.1 |  | 0.30 | Polyketide | luminaolide | Planktothrix paucivesiculata PCC 9631
BGC0000361.1 |  | 0.30 | NRP | gliotoxin, bisdethiobis(methylthio)gliotoxin | Aspergillus fumigatus Af293

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_NJFR.. - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,451,922 - 2,495,866 nt. (total: 43,945 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001185.1 |  | 0.34 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0001615.1 |  | 0.32 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000401.1 |  | 0.29 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001132.1 |  | 0.25 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001302.1 |  | 0.25 | Other | lomofungin | Streptomyces lomondensis
BGC0000454.1 |  | 0.25 | NRP | vanchrobactin | Vibrio anguillarum RV22
BGC0001833.1 |  | 0.25 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.24 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.24 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001844.1 |  | 0.24 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001185.1 |  | 0.67 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0001615.1 |  | 0.66 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000401.1 |  | 0.62 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001132.1 |  | 0.58 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001302.1 |  | 0.58 | Other | lomofungin | Streptomyces lomondensis
BGC0000454.1 |  | 0.58 | NRP | vanchrobactin | Vibrio anguillarum RV22
BGC0001833.1 |  | 0.58 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.58 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.58 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001844.1 |  | 0.57 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 2451921 - 2495866:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2338: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (33..438): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PMPAQGVVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      100% (strong)
ctg1_2345: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (475..877): ser
  NRPSPredictor2: ser
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFSLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)

c00001_NZ_NJFR.. - Region 5 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,102,818 - 4,121,067 nt. (total: 18,250 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.18 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001475.1 |  | 0.17 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0001387.1 |  | 0.16 | Other | nucleocidin | Streptomyces calvus
BGC0001928.1 |  | 0.15 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000294.1 |  | 0.15 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000243.1 |  | 0.14 | Polyketide | macrotetrolide | Streptomyces griseus subsp. griseus
BGC0001289.1 |  | 0.14 | RiPP | penisin | Paenibacillus ehimensis
BGC0001221.1 |  | 0.13 | Other (Phenazine) | marinophenazine A, phenaziterpene A | Streptomyces sp. CNQ-509
BGC0001047.1 |  | 0.08 | NRP, Polyketide | syringolin A | Pseudomonas syringae
BGC0000145.1 |  | 0.08 | Polyketide | salinosporamide A | Salinispora tropica

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.49 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001475.1 |  | 0.47 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0001387.1 |  | 0.47 | Other | nucleocidin | Streptomyces calvus
BGC0001928.1 |  | 0.45 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000294.1 |  | 0.45 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000243.1 |  | 0.44 | Polyketide | macrotetrolide | Streptomyces griseus subsp. griseus
BGC0001289.1 |  | 0.43 | RiPP | penisin | Paenibacillus ehimensis
BGC0001221.1 |  | 0.42 | Other (Phenazine) | marinophenazine A, phenaziterpene A | Streptomyces sp. CNQ-509
BGC0001047.1 |  | 0.31 | NRP, Polyketide | syringolin A | Pseudomonas syringae
BGC0000145.1 |  | 0.30 | Polyketide | salinosporamide A | Salinispora tropica

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_NJFR.. - Region 6 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,122,457 - 4,142,999 nt. (total: 20,543 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002007.1 |  | 0.09 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0001469.1 |  | 0.08 | NRP | marthiapeptide A | Brevibacillus sp. Leaf182
BGC0001437.1 |  | 0.07 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.07 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001480.1 |  | 0.06 | Other | tundrenone | Methylobacter tundripaludum 21/22
BGC0000080.1 |  | 0.04 | Polyketide | jerangolid A, jerangolid D | Sorangium cellulosum
BGC0000014.1 |  | 0.04 | Polyketide | ambruticin | Sorangium cellulosum
BGC0000182.1 |  | 0.03 | Polyketide | pseudomonic acid A | Pseudomonas fluorescens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002007.1 |  | 0.33 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0001469.1 |  | 0.30 | NRP | marthiapeptide A | Brevibacillus sp. Leaf182
BGC0001437.1 |  | 0.28 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.28 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001480.1 |  | 0.26 | Other | tundrenone | Methylobacter tundripaludum 21/22
BGC0000080.1 |  | 0.20 | Polyketide | jerangolid A, jerangolid D | Sorangium cellulosum
BGC0000014.1 |  | 0.18 | Polyketide | ambruticin | Sorangium cellulosum
BGC0000182.1 |  | 0.17 | Polyketide | pseudomonic acid A | Pseudomonas fluorescens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_NJFR.. - Region 7 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,732,746 - 4,758,406 nt. (total: 25,661 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.20 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.16 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001441.1 |  | 0.14 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001758.1 |  | 0.14 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.14 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0000597.1 |  | 0.13 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0000207.1 |  | 0.13 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0000595.1 |  | 0.13 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  | 0.13 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000805.1 |  | 0.13 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.52 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.46 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001441.1 |  | 0.44 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001758.1 |  | 0.43 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.43 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0000597.1 |  | 0.41 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0000207.1 |  | 0.41 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0000595.1 |  | 0.41 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  | 0.41 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000805.1 |  | 0.41 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_NJFR.. - Region 8 - arylpolyene,siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,888,590 - 4,937,020 nt. (total: 48,431 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001499.1 |  |  | 1.05 | Other | aerobactin | Pantoea ananatis
BGC0001498.1 |  |  | 0.75 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0001478.1 |  |  | 0.65 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0001572.1 |  |  | 0.58 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001713.1 |  |  | 0.57 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000939.1 |  |  | 0.54 | Other | aerobactin | Grimontia hollisae
BGC0001555.1 |  |  | 0.47 | RiPP | colicin V | Escherichia coli chi7122
BGC0000940.1 |  |  | 0.45 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0002008.1 |  |  | 0.45 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000941.1 |  |  | 0.41 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001499.1 |  | 0.82 | Other | aerobactin | Pantoea ananatis
BGC0002008.1 |  | 0.75 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0001498.1 |  | 0.73 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0000836.1 |  | 0.70 | Other | APE Ec | Escherichia coli CFT073
BGC0001478.1 |  | 0.66 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000837.1 |  | 0.65 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0001572.1 |  | 0.63 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001713.1 |  | 0.62 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000939.1 |  | 0.59 | Other | aerobactin | Grimontia hollisae
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names