Select genomic region:
Overview
1.1
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1.5
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1.10

### Identified secondary metabolite regions using strictness 'relaxed'

NC_010506.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | siderophore | 822,471 | 833,110 |
Region 2 | PUFA,hglE-KS | 1,764,247 | 1,820,624 | eicosapentaenoic acid | Other | 66%
Region 3 | RiPP-like | 2,207,732 | 2,213,294 |
Region 4 | redox-cofactor | 2,751,670 | 2,773,793 | lankacidin C | NRP + Polyketide | 13%
Region 5 | siderophore | 3,247,671 | 3,259,389 |
Region 6 | hserlactone | 3,664,215 | 3,684,892 |
Region 7 | betalactone | 3,938,048 | 3,967,486 | lipopolysaccharide | Saccharide:Lipopolysaccharide | 11%
Region 8 | resorcinol,RiPP-like | 4,900,676 | 4,941,782 |
Region 9 | arylpolyene | 5,561,613 | 5,605,282 | APE Vf | Other | 45%
Region 10 | RiPP-like | 5,759,607 | 5,770,479 |

NC_010506.1 - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 822,471 - 833,110 nt. (total: 10,640 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001572.1 |  | 0.32 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000940.1 |  | 0.28 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001453.1 |  | 0.28 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000941.1 |  | 0.28 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001478.1 |  | 0.27 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0001531.1 |  | 0.17 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0001499.1 |  | 0.17 | Other | aerobactin | Pantoea ananatis
BGC0000942.1 |  | 0.16 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001985.1 |  | 0.15 | Other | pyrazomycin | Streptomyces candidus
BGC0001498.1 |  | 0.15 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001572.1 |  | 0.66 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000940.1 |  | 0.62 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001453.1 |  | 0.62 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000941.1 |  | 0.62 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001478.1 |  | 0.61 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0001531.1 |  | 0.49 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0001499.1 |  | 0.48 | Other | aerobactin | Pantoea ananatis
BGC0000942.1 |  | 0.47 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001985.1 |  | 0.45 | Other | pyrazomycin | Streptomyces candidus
BGC0001498.1 |  | 0.44 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010506.1 - Region 2 - PUFA,hglE-KS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,764,247 - 1,820,624 nt. (total: 56,378 nt) Show pHMM detection rules used
PUFA: PUFA_KS
hglE-KS: (hglE or hglD)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | PUFA | hglE-KS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000861.1 |  |  | 0.87 | Other | eicosapentaenoic acid | Shewanella sp. BR-2
BGC0000862.1 |  |  | 0.77 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0000863.1 |  |  | 0.63 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0000284.1 |  |  | 0.48 | Polyketide | phenolic lipids | Azotobacter vinelandii DJ
BGC0000869.1 |  |  | 0.44 | Other | heterocyst glycolipids | Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0001872.1 |  |  | 0.41 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0000865.1 |  |  | 0.41 | Other | eicoseicosapentaenoic acid | Photobacterium profundum SS9
BGC0000864.1 |  |  | 0.39 | Other | eicosapentaenoic acid-like compound | Moritella marina ATCC 15381
BGC0001338.1 |  |  | 0.36 | Polyketide | citrinin | Monascus ruber
BGC0000044.1 |  |  | 0.33 | Polyketide | dawenol | Stigmatella aurantiaca DW4/3-1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000861.1 |  | 0.74 | Other | eicosapentaenoic acid | Shewanella sp. BR-2
BGC0000862.1 |  | 0.71 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0000863.1 |  | 0.65 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0000284.1 |  | 0.57 | Polyketide | phenolic lipids | Azotobacter vinelandii DJ
BGC0000869.1 |  | 0.56 | Other | heterocyst glycolipids | Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0001872.1 |  | 0.54 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0000865.1 |  | 0.54 | Other | eicoseicosapentaenoic acid | Photobacterium profundum SS9
BGC0001591.1 |  | 0.53 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.53 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000864.1 |  | 0.52 | Other | eicosapentaenoic acid-like compound | Moritella marina ATCC 15381

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 1764246 - 1820624:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (mal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 1772371 - 1820624:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (mal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1449: mmal
  PKS_AT (434..676): mmal
  ATSignature: (unknown)
  No matches above 50%
  minowa: Methylmalonyl-CoA
  Prediction, score:
    Methylmalonyl-CoA: 9.3
    trans-1,2-CPDA: 0.0
    inactive: 0.0
    fatty_acid: 0.0
    Propionyl-CoA: 0.0
    Methoxymalonyl-CoA: 0.0
    Malonyl-CoA: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0
ctg1_1450: mal
  PKS_AT (620..928): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 79.2%
    inactive: 70.8%
    2-Rhyd-Malonyl-CoA: 54.2%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 76.3
    inactive: 31.6
    Methoxymalonyl-CoA: 30.7
    Methylmalonyl-CoA: 28.6
    CHC-CoA: 20.7
    Propionyl-CoA: 15.1
    fatty_acid: 15.0
    Isobutyryl-CoA: 13.9
    Ethylmalonyl-CoA: 8.5
    trans-1,2-CPDA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0

NC_010506.1 - Region 3 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,207,732 - 2,213,294 nt. (total: 5,563 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.18 | Other | nucleocidin | Streptomyces calvus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.50 | Other | nucleocidin | Streptomyces calvus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010506.1 - Region 4 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,751,670 - 2,773,793 nt. (total: 22,124 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.15 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001925.1 |  | 0.14 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0000874.1 |  | 0.11 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001057.1 |  | 0.10 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0001100.1 |  | 0.09 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001108.1 |  | 0.08 | Polyketide | pederin, pseudopederin, pederone | Uncultured bacterium
BGC0001102.1 |  | 0.08 | NRP, Polyketide | malleilactone | Burkholderia thailandensis E264
BGC0001865.1 |  | 0.08 | Polyketide | elsinochrome C | Parastagonospora nodorum SN15
BGC0001739.1 |  | 0.08 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001338.1 |  | 0.07 | Polyketide | citrinin | Monascus ruber

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.45 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001925.1 |  | 0.44 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0000874.1 |  | 0.39 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001057.1 |  | 0.36 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0001100.1 |  | 0.33 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001108.1 |  | 0.32 | Polyketide | pederin, pseudopederin, pederone | Uncultured bacterium
BGC0001102.1 |  | 0.32 | NRP, Polyketide | malleilactone | Burkholderia thailandensis E264
BGC0001865.1 |  | 0.32 | Polyketide | elsinochrome C | Parastagonospora nodorum SN15
BGC0001739.1 |  | 0.31 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001338.1 |  | 0.29 | Polyketide | citrinin | Monascus ruber

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010506.1 - Region 5 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,247,671 - 3,259,389 nt. (total: 11,719 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001453.1 |  | 0.19 | Other | desferrioxamine | Streptomyces argillaceus
BGC0001499.1 |  | 0.13 | Other | aerobactin | Pantoea ananatis
BGC0001713.1 |  | 0.12 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001498.1 |  | 0.12 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0000939.1 |  | 0.11 | Other | aerobactin | Grimontia hollisae
BGC0001555.1 |  | 0.10 | RiPP | colicin V | Escherichia coli chi7122
BGC0001870.1 |  | 0.10 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001453.1 |  | 0.50 | Other | desferrioxamine | Streptomyces argillaceus
BGC0001499.1 |  | 0.41 | Other | aerobactin | Pantoea ananatis
BGC0001713.1 |  | 0.39 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001498.1 |  | 0.39 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0000939.1 |  | 0.38 | Other | aerobactin | Grimontia hollisae
BGC0001555.1 |  | 0.36 | RiPP | colicin V | Escherichia coli chi7122
BGC0001870.1 |  | 0.36 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
NC_010506.1 - Region 6 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,664,215 - 3,684,892 nt. (total: 20,678 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001928.1 |  | 0.15 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000329.1 |  | 0.06 | NRP | corpeptin A, corpeptin B | Pseudomonas corrugata
BGC0001157.1 |  | 0.05 | RiPP | bottromycin A2 | Streptomyces scabiei 87.22
BGC0000468.1 |  | 0.05 | RiPP | bottromycin A2 | Streptomyces bottropensis
BGC0000469.1 |  | 0.05 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0000693.1 |  | 0.04 | Saccharide | butirosin A, butirosin B | Bacillus circulans
BGC0000961.1 |  | 0.04 | NRP, Polyketide | bactobolin | Burkholderia thailandensis E264
BGC0000700.1 |  | 0.04 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000695.1 |  | 0.04 | Saccharide | fortimicin | Micromonospora olivasterospora

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001928.1 |  | 0.45 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000329.1 |  | 0.25 | NRP | corpeptin A, corpeptin B | Pseudomonas corrugata
BGC0001157.1 |  | 0.24 | RiPP | bottromycin A2 | Streptomyces scabiei 87.22
BGC0000468.1 |  | 0.23 | RiPP | bottromycin A2 | Streptomyces bottropensis
BGC0000469.1 |  | 0.23 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0000693.1 |  | 0.19 | Saccharide | butirosin A, butirosin B | Bacillus circulans
BGC0000961.1 |  | 0.19 | NRP, Polyketide | bactobolin | Burkholderia thailandensis E264
BGC0000700.1 |  | 0.18 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000695.1 |  | 0.17 | Saccharide | fortimicin | Micromonospora olivasterospora

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010506.1 - Region 7 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,938,048 - 3,967,486 nt. (total: 29,439 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001778.1 |  | 0.27 | Other | showdomycin | Streptomyces showdoensis
BGC0000234.1 |  | 0.25 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000783.1 |  | 0.25 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0001983.1 |  | 0.21 | Other | triacsins | Kitasatospora aureofaciens
BGC0000258.1 |  | 0.21 | Polyketide | prodigiosin | Serratia sp.
BGC0000259.1 |  | 0.20 | Polyketide | prodigiosin | Serratia marcescens
BGC0000890.1 |  | 0.20 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0001465.1 |  | 0.20 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0000891.1 |  | 0.19 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000261.1 |  | 0.19 | Polyketide | R1128 | Streptomyces sp. R1128

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001778.1 |  | 0.60 | Other | showdomycin | Streptomyces showdoensis
BGC0000234.1 |  | 0.58 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000783.1 |  | 0.58 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0001983.1 |  | 0.53 | Other | triacsins | Kitasatospora aureofaciens
BGC0000258.1 |  | 0.53 | Polyketide | prodigiosin | Serratia sp.
BGC0000259.1 |  | 0.52 | Polyketide | prodigiosin | Serratia marcescens
BGC0000890.1 |  | 0.52 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0001465.1 |  | 0.52 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0000891.1 |  | 0.52 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000261.1 |  | 0.50 | Polyketide | R1128 | Streptomyces sp. R1128

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010506.1 - Region 8 - RiPP-like,resorcinol
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 4,900,676 - 4,941,782 nt. (total: 41,107 nt) Show pHMM detection rules used
resorcinol: DarB
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | resorcinol | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001526.1 |  |  | 0.23 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001525.1 |  |  | 0.21 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0001897.1 |  |  | 0.20 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001831.1 |  |  | 0.19 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001495.1 |  |  | 0.16 | Polyketide | actinoallolide A | Actinoallomurus fulvus
BGC0001241.1 |  |  | 0.16 | Terpene | ergotamine | Claviceps fusiformis
BGC0001267.1 |  |  | 0.16 | Terpene | lysergic acid, elymoclavine | Claviceps fusiformis
BGC0001739.1 |  |  | 0.16 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001865.1 |  |  | 0.16 | Polyketide | elsinochrome C | Parastagonospora nodorum SN15
BGC0001458.1 |  |  | 0.15 | Other (Aminocoumarin) | salinipostin G | Salinispora tropica CNB-440

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001526.1 |  | 0.56 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001525.1 |  | 0.54 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0001897.1 |  | 0.53 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001831.1 |  | 0.51 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001241.1 |  | 0.47 | Terpene | ergotamine | Claviceps fusiformis
BGC0001267.1 |  | 0.47 | Terpene | lysergic acid, elymoclavine | Claviceps fusiformis
BGC0001458.1 |  | 0.45 | Other (Aminocoumarin) | salinipostin G | Salinispora tropica CNB-440
BGC0000511.1 |  | 0.45 | RiPP | ericin S | Bacillus subtilis
BGC0001588.1 |  | 0.45 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001589.1 |  | 0.45 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
NC_010506.1 - Region 9 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 5,561,613 - 5,605,282 nt. (total: 43,670 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.31 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.28 | Other | APE Ec | Escherichia coli CFT073
BGC0000889.1 |  | 0.23 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0000228.1 |  | 0.22 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002000.1 |  | 0.22 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000886.1 |  | 0.22 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0002029.1 |  | 0.21 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.21 | Other | ferroverdin | Streptomyces lunaelactis
BGC0001104.1 |  | 0.21 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.64 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.62 | Other | APE Ec | Escherichia coli CFT073
BGC0000889.1 |  | 0.56 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0000228.1 |  | 0.56 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002000.1 |  | 0.55 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000886.1 |  | 0.54 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000248.1 |  | 0.54 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0002029.1 |  | 0.54 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.54 | Other | ferroverdin | Streptomyces lunaelactis
BGC0001104.1 |  | 0.54 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010506.1 - Region 10 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 5,759,607 - 5,770,479 nt. (total: 10,873 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000585.1 |  | 0.20 | RiPP | microcin C7 | Escherichia coli
BGC0000925.1 |  | 0.17 | Other | quinolobactin | Pseudomonas fluorescens
BGC0000812.1 |  | 0.15 | Alkaloid | huperzine A | Shiraia sp. slf14

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000585.1 |  | 0.53 | RiPP | microcin C7 | Escherichia coli
BGC0000925.1 |  | 0.48 | Other | quinolobactin | Pseudomonas fluorescens
BGC0000812.1 |  | 0.46 | Alkaloid | huperzine A | Shiraia sp. slf14

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names