LOCUS       NZ_CP059567.1           7194 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP059567.1 Neisseria shayeganii strain DSM 22244 chromosome,
            complete genome.
ACCESSION   NZ_CP059567
VERSION     NZ_CP059567.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:53:20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2412550
            Orig. end    :: 2419744
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7194
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2417550:2418423](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..7194
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7194
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="7"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(541..1371)
                     /locus_tag="ctg1_2294"
                     /transl_table=11
                     /translation="MFHTSPLTYEQWLRQSGLPRLEGRLLLQACCGLSHAQLISRGGET
                     VPAAQWADLNALAQRRQNGEPLAYLLGWREFYGRRFRVSPAVLIPRPETEHLLEAALER
                     LPAGGRVWDLGTGSGALAVSVALERPDAAVRASDLSREALAVAQENAKALGARIEFACG
                     SWFEAQPAAAGHFDILLSNPPYIEQDDPHLQQGDLRFEPAAALTDFGDGLAHIRTLAAG
                     AARHLKAGGWLMLEHGWNQGPAVRGILTENRFQDVATLPDLAGLDRVTLGRLPD"
     aSDomain        complement(550..1317)
                     /aSDomain="TIGR00536"
                     /aSTool="tigrfam"
                     /description="hemK_fam: methyltransferase, HemK family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2294_0062"
                     /evalue="2.00E-66"
                     /identifier="TIGR00536"
                     /label="ctg1_2294"
                     /locus_tag="ctg1_2294"
                     /protein_end="274"
                     /protein_start="18"
                     /score="222.0"
                     /tool="antismash"
                     /translation="PRLEGRLLLQACCGLSHAQLISRGGETVPAAQWADLNALAQRRQN
                     GEPLAYLLGWREFYGRRFRVSPAVLIPRPETEHLLEAALERLPAGGRVWDLGTGSGALA
                     VSVALERPDAAVRASDLSREALAVAQENAKALGARIEFACGSWFEAQPAAAGHFDILLS
                     NPPYIEQDDPHLQQGDLRFEPAAALTDFGDGLAHIRTLAAGAARHLKAGGWLMLEHGWN
                     QGPAVRGILTENRFQDVATLPDLAGLDRVTLGRL"
     aSDomain        complement(562..1302)
                     /aSDomain="TIGR03534"
                     /aSTool="tigrfam"
                     /description="RF_mod_PrmC: protein-(glutamine-N5)
                     methyltransferase, release factor-specific"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2294_0061"
                     /evalue="6.00E-83"
                     /identifier="TIGR03534"
                     /label="ctg1_2294"
                     /locus_tag="ctg1_2294"
                     /protein_end="270"
                     /protein_start="23"
                     /score="276.1"
                     /tool="antismash"
                     /translation="RLLLQACCGLSHAQLISRGGETVPAAQWADLNALAQRRQNGEPLA
                     YLLGWREFYGRRFRVSPAVLIPRPETEHLLEAALERLPAGGRVWDLGTGSGALAVSVAL
                     ERPDAAVRASDLSREALAVAQENAKALGARIEFACGSWFEAQPAAAGHFDILLSNPPYI
                     EQDDPHLQQGDLRFEPAAALTDFGDGLAHIRTLAAGAARHLKAGGWLMLEHGWNQGPAV
                     RGILTENRFQDVATLPDLAGLDRVT"
     PFAM_domain     complement(802..1071)
                     /aSDomain="MTS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05175.16"
                     /description="Methyltransferase small domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2294_0219"
                     /evalue="3.80E-14"
                     /label="ctg1_2294"
                     /locus_tag="ctg1_2294"
                     /protein_end="190"
                     /protein_start="100"
                     /score="52.8"
                     /tool="antismash"
                     /translation="ALERLPAGGRVWDLGTGSGALAVSVALERPDAAVRASDLSREALA
                     VAQENAKALGARIEFACGSWFEAQPAAAGHFDILLSNPPYIEQDD"
     PFAM_domain     complement(1156..1344)
                     /aSDomain="PrmC_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17827.3"
                     /description="PrmC N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2294_0218"
                     /evalue="1.10E-12"
                     /label="ctg1_2294"
                     /locus_tag="ctg1_2294"
                     /protein_end="72"
                     /protein_start="9"
                     /score="48.4"
                     /tool="antismash"
                     /translation="EQWLRQSGLPRLEGRLLLQACCGLSHAQLISRGGETVPAAQWADL
                     NALAQRRQNGEPLAYLLG"
     CDS             1462..2607
                     /locus_tag="ctg1_2295"
                     /transl_table=11
                     /translation="MTRTLIHFFRSEPAAGIVLMLAALAGIITANSAYAPQYFGALSSY
                     VAGLSVAHWINDGLMAVFFLFVGLEVKRELLEGELDSHAKRFLPAVAAAGGLLVPALVY
                     LLFNTSGEAAQGWAAPAATDIAFALGVLAILGSRVPASLKIFLTALAIMDDLAVIVIIA
                     LFYTDQIAMLYLGLAALVLAALFVLNRKGVLRSAPYLVLGSLLWFFFLKSGIHATLAGV
                     LLAFTIPLRVLDTVEEAPLLKWEHALDNWVSFLVVPVFGFANAGVSFAGFEWSVLLSPV
                     VLGIAAGLFVGKQLGVFSAVWLAVKLGWAKLPEGASWLQLYGVALLCGIGFTMSLFISL
                     LAFDLPVMQDQAKIGVFVGSGLAAVLGFAVLWAAGRKTAAS"
     PFAM_domain     1480..2574
                     /aSDomain="Na_H_antiport_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06965.14"
                     /description="Na+/H+ antiporter 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2295_0220"
                     /evalue="2.20E-136"
                     /label="ctg1_2295"
                     /locus_tag="ctg1_2295"
                     /protein_end="371"
                     /protein_start="6"
                     /score="454.8"
                     /tool="antismash"
                     /translation="HFFRSEPAAGIVLMLAALAGIITANSAYAPQYFGALSSYVAGLSV
                     AHWINDGLMAVFFLFVGLEVKRELLEGELDSHAKRFLPAVAAAGGLLVPALVYLLFNTS
                     GEAAQGWAAPAATDIAFALGVLAILGSRVPASLKIFLTALAIMDDLAVIVIIALFYTDQ
                     IAMLYLGLAALVLAALFVLNRKGVLRSAPYLVLGSLLWFFFLKSGIHATLAGVLLAFTI
                     PLRVLDTVEEAPLLKWEHALDNWVSFLVVPVFGFANAGVSFAGFEWSVLLSPVVLGIAA
                     GLFVGKQLGVFSAVWLAVKLGWAKLPEGASWLQLYGVALLCGIGFTMSLFISLLAFDLP
                     VMQDQAKIGVFVGSGLAAVLGFAVL"
     aSDomain        1483..2574
                     /aSDomain="TIGR00773"
                     /aSTool="tigrfam"
                     /description="NhaA: Na+/H+ antiporter NhaA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2295_0063"
                     /evalue="4.20E-129"
                     /identifier="TIGR00773"
                     /label="ctg1_2295"
                     /locus_tag="ctg1_2295"
                     /protein_end="371"
                     /protein_start="7"
                     /score="428.7"
                     /tool="antismash"
                     /translation="FFRSEPAAGIVLMLAALAGIITANSAYAPQYFGALSSYVAGLSVA
                     HWINDGLMAVFFLFVGLEVKRELLEGELDSHAKRFLPAVAAAGGLLVPALVYLLFNTSG
                     EAAQGWAAPAATDIAFALGVLAILGSRVPASLKIFLTALAIMDDLAVIVIIALFYTDQI
                     AMLYLGLAALVLAALFVLNRKGVLRSAPYLVLGSLLWFFFLKSGIHATLAGVLLAFTIP
                     LRVLDTVEEAPLLKWEHALDNWVSFLVVPVFGFANAGVSFAGFEWSVLLSPVVLGIAAG
                     LFVGKQLGVFSAVWLAVKLGWAKLPEGASWLQLYGVALLCGIGFTMSLFISLLAFDLPV
                     MQDQAKIGVFVGSGLAAVLGFAVL"
     CDS             2715..3794
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 61.2; E-value: 1.9e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2296"
                     /transl_table=11
                     /translation="MNPETLRAALEAVPLPDSRLSIGSEKALKQLAVDNGTLQIGLQFG
                     LPVAHLAPALEQTVAEAVTAAGWNGPLNIQIGSRIEAHQVQPGMRTLAGVKNIVAVASG
                     KGGVGKSTTSANLAVAMQRMGARVGVLDADLYGPSQPTMLGVAGQTPAQQNGRFLPVRS
                     PEGIQVMSIGFLVDTDQAVVWRGPMVSQALQQLLFQSEWDGVDYLFIDLPPGTGDIQLT
                     LSQKIPVTGAVVVTTPQDIALIDARKAVDMFRKVNIPIFGVLENMSVHICSRCGHQEAL
                     FGQDGGKALAEQLNVPLLGQLPLSLPVREAMDTGQAAALQAAHPAIADVYTAAAWQVAQ
                     AVAAKGRDFSSRFPKIVVE"
     PFAM_domain     2997..3722
                     /aSDomain="ParA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10609.11"
                     /description="NUBPL iron-transfer P-loop NTPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2296_0221"
                     /evalue="1.40E-97"
                     /label="ctg1_2296"
                     /locus_tag="ctg1_2296"
                     /protein_end="336"
                     /protein_start="94"
                     /score="326.0"
                     /tool="antismash"
                     /translation="VKNIVAVASGKGGVGKSTTSANLAVAMQRMGARVGVLDADLYGPS
                     QPTMLGVAGQTPAQQNGRFLPVRSPEGIQVMSIGFLVDTDQAVVWRGPMVSQALQQLLF
                     QSEWDGVDYLFIDLPPGTGDIQLTLSQKIPVTGAVVVTTPQDIALIDARKAVDMFRKVN
                     IPIFGVLENMSVHICSRCGHQEALFGQDGGKALAEQLNVPLLGQLPLSLPVREAMDTGQ
                     AAALQAAHPAIADVYTAAAW"
     CDS             3867..4283
                     /locus_tag="ctg1_2297"
                     /transl_table=11
                     /translation="MSVYDPNNIFAKILRGEIPNHTVYEDEHTLAFMDVMPQARGHVLV
                     IPKTAAVELSDLPLDAARAVMATAQKVMAAQRKVLQRQGIVQMQLNHAQAGQSVFHYHL
                     HLIPSNVHELGRHEGGMADHAELAALAAELRAAL"
     PFAM_domain     3909..4196
                     /aSDomain="HIT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01230.25"
                     /description="HIT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2297_0222"
                     /evalue="3.80E-24"
                     /label="ctg1_2297"
                     /locus_tag="ctg1_2297"
                     /protein_end="110"
                     /protein_start="14"
                     /score="85.3"
                     /tool="antismash"
                     /translation="RGEIPNHTVYEDEHTLAFMDVMPQARGHVLVIPKTAAVELSDLPL
                     DAARAVMATAQKVMAAQRKVLQRQGIVQMQLNHAQAGQSVFHYHLHLIPSN"
     CDS             4460..4825
                     /locus_tag="ctg1_2298"
                     /transl_table=11
                     /translation="MKKNSVLALATALSALTVGAYSVSHAHGHHGHHHPAVEKAQEAAC
                     GAAKAGEAACGAHKAHEAACGAAKSGEAACGAHKASEAACGAAKASEAACGAQNKAGEA
                     ACGAHGKSGEAACGAAR"
     CDS             5001..5873
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2299"
                     /sec_met_domain="DUF692 (E-value: 4.8e-119, bitscore:
                     393.6, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMHAPTPRPLPAARAGLGYRRSFAEELLGLDPQQCPIAFLEIAPE
                     NWARMGGAALRQFDQAAERFPVACHGLSLSLGGRDPLNTALLADIKRLMHRYGMSFFSE
                     HLSYCGHEGQLYDLLPLPFTGEMVRHTAARIRQVQDFLGMQIAVENTSYYVHSDLAEMD
                     EVAFLNAVAAEADCAIHLDINNIFVNQTNHGLLDARDFLDRVDGKRVRYLHIAGHEAEA
                     EDLLIDTHGETVRDQVWDLLDYAYRVLPQVPPTLLERDFNFPPFAELLAEVAHIDALQQ
                     PYRSEYAAA"
     PFAM_domain     5043..5840
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2299_0223"
                     /evalue="6.20E-98"
                     /label="ctg1_2299"
                     /locus_tag="ctg1_2299"
                     /protein_end="280"
                     /protein_start="14"
                     /score="327.3"
                     /tool="antismash"
                     /translation="AGLGYRRSFAEELLGLDPQQCPIAFLEIAPENWARMGGAALRQFD
                     QAAERFPVACHGLSLSLGGRDPLNTALLADIKRLMHRYGMSFFSEHLSYCGHEGQLYDL
                     LPLPFTGEMVRHTAARIRQVQDFLGMQIAVENTSYYVHSDLAEMDEVAFLNAVAAEADC
                     AIHLDINNIFVNQTNHGLLDARDFLDRVDGKRVRYLHIAGHEAEAEDLLIDTHGETVRD
                     QVWDLLDYAYRVLPQVPPTLLERDFNFPPFAELLAEVAHIDALQ"
     CDS             5860..6576
                     /locus_tag="ctg1_2300"
                     /transl_table=11
                     /translation="MPQPDAAAYQAALAEFVRNPEQAAPPGICPERAAVYTRLTRNNVR
                     SLVRRCFTAARPLADAEVWADLENRFLAEAAPASPYFSDIPALFVEYARTDGRLPAPLL
                     ELMDFETVQLAAETAPLFDQAPSSWRHDTPLGFSPAAFIRRYPVDFISSGLQGFADQAA
                     EVLVWRNRQDAVMHRLLDAQLLPLLEHFAGQTDSLNGLLQALAEVLPDAETLRPWLAEQ
                     VDVWVRQGVLLPKEAA"
     PFAM_domain     5884..6135
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2300_0224"
                     /evalue="1.20E-12"
                     /label="ctg1_2300"
                     /locus_tag="ctg1_2300"
                     /protein_end="92"
                     /protein_start="8"
                     /score="48.0"
                     /tool="antismash"
                     /translation="YQAALAEFVRNPEQAAPPGICPERAAVYTRLTRNNVRSLVRRCFT
                     AARPLADAEVWADLENRFLAEAAPASPYFSDIPALFVEY"
     CDS             6573..7154
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 114.5;
                     E-value: 7.1e-35)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2301"
                     /transl_table=11
                     /translation="MTAWSWNDADTAELRQKLLRFAQLQLRDAQWAEDVVQDTLIKAFT
                     KQGQFQAAAQWQTWVFAILKNTILDLLRQHKTRLQWQVSSDDEEFIDAVHEQLFDESGH
                     WTPSGSPQAWAQPESSLQQQDFMRTLHHCLQDLPENTARVFMLREIMGLDVAEICEQTG
                     ISADNCYTILHRARNGLRRCLQSNWFDEQA"
     aSDomain        6594..7148
                     /aSDomain="TIGR02943"
                     /aSTool="tigrfam"
                     /description="Sig70_famx1: RNA polymerase sigma-70 factor,
                     TIGR02943 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2301_0064"
                     /evalue="1.30E-67"
                     /identifier="TIGR02943"
                     /label="ctg1_2301"
                     /locus_tag="ctg1_2301"
                     /protein_end="192"
                     /protein_start="7"
                     /score="225.2"
                     /tool="antismash"
                     /translation="DADTAELRQKLLRFAQLQLRDAQWAEDVVQDTLIKAFTKQGQFQA
                     AAQWQTWVFAILKNTILDLLRQHKTRLQWQVSSDDEEFIDAVHEQLFDESGHWTPSGSP
                     QAWAQPESSLQQQDFMRTLHHCLQDLPENTARVFMLREIMGLDVAEICEQTGISADNCY
                     TILHRARNGLRRCLQSNWFDEQ"
     PFAM_domain     6612..6800
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2301_0225"
                     /evalue="2.70E-09"
                     /label="ctg1_2301"
                     /locus_tag="ctg1_2301"
                     /protein_end="76"
                     /protein_start="13"
                     /score="36.8"
                     /tool="antismash"
                     /translation="LRQKLLRFAQLQLRDAQWAEDVVQDTLIKAFTKQGQFQAAAQWQT
                     WVFAILKNTILDLLRQHK"
     aSDomain        6615..7124
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2301_0065"
                     /evalue="2.00E-26"
                     /identifier="TIGR02937"
                     /label="ctg1_2301"
                     /locus_tag="ctg1_2301"
                     /protein_end="184"
                     /protein_start="14"
                     /score="90.5"
                     /tool="antismash"
                     /translation="RQKLLRFAQLQLRDAQWAEDVVQDTLIKAFTKQGQFQAAAQWQTW
                     VFAILKNTILDLLRQHKTRLQWQVSSDDEEFIDAVHEQLFDESGHWTPSGSPQAWAQPE
                     SSLQQQDFMRTLHHCLQDLPENTARVFMLREIMGLDVAEICEQTGISADNCYTILHRAR
                     NGLRRCL"
     PFAM_domain     6957..7103
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2301_0226"
                     /evalue="4.20E-11"
                     /label="ctg1_2301"
                     /locus_tag="ctg1_2301"
                     /protein_end="177"
                     /protein_start="128"
                     /score="42.4"
                     /tool="antismash"
                     /translation="TLHHCLQDLPENTARVFMLREIMGLDVAEICEQTGISADNCYTIL
                     HRAR"
ORIGIN
        1 aacacacggc cgcacctgcc gtttccagtc gccgccagga agcccctgtc cctgctgagg
       61 ccgaattcga cggtttccgc atcggccaaa acgtgcgcca cgccaaattc ggcaccggtg
      121 tcatcatcga cggcgtgcag aaaagcggca gcgcccgcct caccatcaac ttcggcaagc
      181 agggcatcaa agagctggac acccagtttg ccaaattgga agtgctgtcg gcttaaacag
      241 ccgcctagtt ctcagagcaa gattcaaggc tacctgaaag cgtttcaggt agcctttgtc
      301 gttacggcat gaaagtgcag ttatggcttt ttaatgaaga ggctgagacc tttgcaaaac
      361 cccctgatgt ggatgcagtt caaggcgtag cagcgcagcg agcgtgaacg tcaggaatcc
      421 ctgtgggaca gacatatcat acagataggc aagtgagcga gcagtaccca tagggcataa
      481 acgcacaacg cagaaatgcg ccgcagatgg gggttttgaa aaagtctcag cctgagtgct
      541 tcaatccggc aggcggccta aagtgacgcg gtccagtccc gccaaatcgg gcagggtggc
      601 cacgtcttga aaccgatttt ccgtcagaat gccgcgcacg gccgggcctt ggttccagcc
      661 gtgttccagc atcagccagc cgccggcttt gaggtggcgg gcggcgccgg cggccagggt
      721 gcggatgtgg gcgaggccgt cgccgaaatc ggtgagcgcg gcggcaggct cgaagcgtag
      781 gtcgccctgt tgcaaatgcg ggtcgtcctg ctcgatatag ggtgggttgg agagcagaat
      841 atcgaagtgt ccggcggcgg ccggctgtgc ctcaaaccag gagccgcagg caaattcgat
      901 acgggcgccg agcgccttgg cattttcctg cgccaccgcc agggcttcgc ggctgaggtc
      961 ggaggcgcgc acggcggcat cgggccgttc cagcgccacg ctcaccgcca gcgcgccgct
     1021 gccggtgccc aaatcccaca cgcggccgcc ggccggcagg cgttcaagcg cggcttccag
     1081 caggtgttcg gtttcggggc ggggaatcag caccgcgggc gagacgcgga aacggcggcc
     1141 gtaaaattcg cgccagccga gcagataggc cagcggttcg ccgttttgcc gccgctgcgc
     1201 cagcgcgttc aaatcggccc attgcgccgc cggcacggtt tcgccaccgc ggctgatgag
     1261 ctgggcatgg ctgaggccgc agcaggcttg cagcagcaag cggccttcca aacgcggcag
     1321 gccgctttgg cgcagccatt gttcgtaagt gaggggggaa gtgtggaaca tgatgtttcg
     1381 ctgggtgttt caggtagcct gctgcggcga cgtgaaagaa ttatgctata atcacggatt
     1441 aattgataga ttaggtaaat aatgacccgt acacttatcc actttttccg ttccgagccg
     1501 gctgccggca ttgtgttgat gttggccgcg ctggccggaa ttataacggc caactccgcc
     1561 tatgcgccgc aatatttcgg cgccttgtcg tcttatgtgg ccggcctgag cgtggcgcac
     1621 tggatcaacg acggcctgat ggcggtgttt tttctgtttg ttggcttgga agtgaaacgc
     1681 gagctgttgg aaggcgagct cgacagccac gccaaacgct ttctgccggc cgtagcggcg
     1741 gccggcggcc tgctggtgcc ggccttggtg tatctgctgt tcaacacttc gggcgaggca
     1801 gcccaaggct gggcggcgcc ggcggccacc gatattgcgt ttgccttggg cgtgctggcg
     1861 attctcggca gccgtgtgcc ggcttcgctg aaaatcttcc tcacggcttt ggcgattatg
     1921 gacgacttgg cggtgattgt gatcatcgcg ctgttttaca ccgatcaaat cgccatgctg
     1981 tatttgggtt tggcggcgct ggtgttggcg gccttgtttg tgctcaaccg caaaggtgtg
     2041 ttgcgcagtg cgccgtattt ggtattgggc agcctgctgt ggtttttctt cctcaaatcg
     2101 ggcatccacg ccacgctggc cggcgtgctg ttggccttca ccattccgct gcgtgtattg
     2161 gatacggtgg aagaagcgcc gctgctgaaa tgggaacacg ctttggacaa ctgggtgtcg
     2221 tttttggtgg tgcccgtatt cggttttgcc aatgccgggg tgtcgtttgc cggcttcgaa
     2281 tggtcggtgc tgctctcgcc tgtggtattg ggcattgccg ccggcttgtt tgtgggcaag
     2341 caattgggcg tgttcagcgc ggtgtggctg gcggtgaagc tgggctgggc caaactgccg
     2401 gaaggcgctt cttggctgca gctttacggc gtggcgctgc tgtgcggcat cggttttacc
     2461 atgagtttgt tcatcagcct gctggcgttt gatctgcccg tcatgcagga tcaggccaaa
     2521 atcggcgttt tcgtcggttc cggtttggct gcggtattgg gtttcgccgt actctgggcc
     2581 gccggccgca aaactgctgc aagctgatga cggcagaata ggatacaggc tacctgaaag
     2641 cgtttcaggt agcctttctg ctaaaatgca ggttcacaac cagcacacac attcatctga
     2701 cacaaggaat ccccatgaat ccggaaactt tgcgcgccgc tttagaagcg gtgccgctgc
     2761 ccgacagccg cctgagcatc ggcagcgaaa aagcgctcaa acagctggcg gtggacaacg
     2821 gcacgctgca aatcggcctg cagttcggcc tgccggtggc ccaccttgca ccggctttag
     2881 agcaaacggt ggccgaagcc gtgaccgcag ccggttggaa cggcccgcta aacatccaaa
     2941 ttggcagccg gattgaggcc catcaggtgc agccgggcat gcgcaccttg gccggtgtga
     3001 aaaatatagt cgccgtggct tcgggcaaag gcggcgtggg caaatccacc acctcggcca
     3061 atctggcggt ggccatgcag cgcatgggcg cgcgcgtggg cgtgctggat gccgacctct
     3121 acggccccag ccagccgacc atgctcggtg tggcgggaca aacccccgcc cagcaaaacg
     3181 gccgtttcct gcccgtgcgc tcgccggaag gcatccaagt gatgtcgatc ggctttctgg
     3241 tcgacaccga ccaggccgtg gtatggcgtg ggccgatggt cagccaggcg ctgcaacagc
     3301 tgctttttca aagcgagtgg gacggggtgg actatctgtt tatcgacctg ccgcctggca
     3361 ccggcgacat ccagctgacc ttgtcgcaga aaattccggt gaccggcgcg gtggtggtga
     3421 ccaccccgca agacatcgcc ctgattgacg cccgcaaggc ggtggacatg ttccgcaagg
     3481 tgaatattcc gattttcggc gtgctggaaa atatgtcggt gcacatctgc agccgctgcg
     3541 gccatcagga agccctgttc ggccaagacg gcggcaaggc gttggcagaa cagctcaacg
     3601 tgccgctgct gggccagctg cccttgagcc tgccggtgcg cgaagccatg gatacaggcc
     3661 aagccgccgc gctgcaggcc gcccaccccg cgattgccga tgtttacacc gccgccgcct
     3721 ggcaggtggc gcaggccgtg gccgccaaag ggcgcgattt cagcagccgc ttccccaaaa
     3781 tcgtggtgga atagcccgcc ccgccggcaa caaactttgt tatacaatag cgctcccgtt
     3841 ttccagtcaa accgcggagc gcttttatgt ctgtctacga tccgaacaat atcttcgcca
     3901 aaatcctgcg cggcgaaatc cccaaccaca ccgtttacga agacgagcac acgctggcct
     3961 ttatggacgt gatgccgcag gcgcgcggcc atgtgctggt gattccgaaa accgccgctg
     4021 tcgagctttc cgacctgccg ctggacgccg cccgcgccgt gatggccacc gcccagaaag
     4081 tgatggcggc gcagcgtaaa gtgctgcagc ggcagggcat cgtgcagatg cagctcaacc
     4141 acgcccaagc cggccaaagc gtgttccact accacctgca cctgattccc tccaatgtgc
     4201 acgaactggg ccgccacgaa ggcggcatgg ccgatcacgc cgaactggcc gcgctggcgg
     4261 ccgagctgcg cgccgcgctc taaaccccgc cgtcactaat ttggagatta aatttatagt
     4321 taaatcaatt ctctaattca gaatccccgc tccgccgtca gaaaaaacgg tagggcggcg
     4381 tccaagctgg caaaccggta tgccatggcg agccggcttg gtttttactc cctctccaat
     4441 ctacgaaagg aatttcacga tgaaaaaaaa ctccgttttg gccctggcca ctgccctgtc
     4501 tgccctgacc gtgggtgcgt actctgtcag ccatgcgcac ggccatcatg gccaccacca
     4561 cccggccgtt gaaaaagcac aagaagcggc ctgtggtgcc gccaaagccg gcgaagccgc
     4621 ttgcggtgca cacaaagccc acgaagcggc ctgtggcgcg gccaaatccg gtgaagccgc
     4681 ttgcggcgcc cataaagcca gcgaagcggc ctgcggtgcg gccaaagcga gcgaagccgc
     4741 ttgcggcgct caaaacaaag ccggtgaagc ggcttgcggt gcgcacggca aatccggcga
     4801 agccgcctgc ggcgctgccc gctaaacggt tttcaggcta cctgaaaccg tttcaggtag
     4861 cctgagtttt tggcaaaacc cttcctccgg ccaaacatgt caaacaggga tgtttttgcc
     4921 aaaacctcgt ttccgcccgg ctccggccag cggctctgtc gcaccgtttc acttccatgc
     4981 cccgccttcg gacacccttg atgatgcacg cccctactcc gcgccccctg cccgccgccc
     5041 gcgccggctt gggctaccgc cgctcctttg cagaagaact gctcggcctc gatccgcagc
     5101 aatgccccat cgcctttcta gaaatcgcgc ccgaaaactg ggcccgcatg ggcggcgcgg
     5161 ccctgcgcca atttgaccaa gcggccgaac gcttccccgt ggcctgccac ggcctctccc
     5221 tctccttggg cggccgtgat ccgctcaaca ccgccctctt ggccgacatc aaacggctga
     5281 tgcaccgcta cggcatgagc tttttctccg agcacctgag ctattgcggt cacgaaggcc
     5341 agttatacga tttgctgccg ctgccgttta ccggcgagat ggtgcggcac actgccgcac
     5401 gcatccgcca ggtgcaggac ttcctcggca tgcagattgc agtggaaaac acgtcttact
     5461 atgtgcacag cgatttggcc gaaatggacg aagtggcctt tttgaatgcg gtggcggccg
     5521 aagccgactg cgccatccat ctggacatca acaacatctt cgtcaaccaa accaaccatg
     5581 gcctgctcga cgcccgcgac tttctcgacc gggtggacgg caaacgggtg cgctatctgc
     5641 acatcgccgg ccacgaagcg gaagcggagg acttgctgat cgacacccat ggcgaaaccg
     5701 tgcgcgatca ggtatgggat ttgctcgact acgcctaccg cgtgttgccc caagtgccgc
     5761 cgaccctgct cgagcgcgac ttcaacttcc ccccgtttgc cgaactgttg gccgaagtcg
     5821 cacacatcga tgctttgcaa caaccctacc ggagtgaata tgccgcagcc tgatgcggcc
     5881 gcctaccagg cggcactggc cgaatttgtc cgcaaccccg aacaggctgc gccgcccggt
     5941 atttgccccg aacgggccgc cgtctatacc cgcctgaccc gcaacaatgt gcgcagtctc
     6001 gtgcgccgct gcttcacggc cgcccgccct ttggccgacg ccgaagtgtg ggccgacttg
     6061 gaaaaccgct ttctggccga agccgccccc gccagccctt atttcagcga catccccgcc
     6121 ctgtttgtcg aatacgcccg caccgacgga cggctgcccg ccccgctgct tgagctgatg
     6181 gatttcgaaa ccgtacagct ggccgccgaa accgccccgc tgtttgacca ggccccgtca
     6241 agctggcggc acgacacccc gctgggcttc tccccggccg cctttatccg ccgctatccg
     6301 gtggatttca tcagcagcgg cctgcaaggc tttgccgacc aagcggcaga ggtgctggtg
     6361 tggcgcaacc gccaagatgc cgtgatgcac cgcctgctcg atgcccaact gctgccgctg
     6421 ctcgaacact tcgccgggca gaccgactcc ctaaacggct tgctgcaggc gctggccgaa
     6481 gtgctgcccg atgcggaaac cctccgccct tggttggccg aacaagtcga tgtctgggtg
     6541 cggcaaggcg tcttgctgcc gaaggaggcc gcatgaccgc ctggagctgg aacgatgccg
     6601 acaccgccga gctgcgccag aaactgctgc gcttcgccca actgcagctg cgcgatgcgc
     6661 aatgggccga agacgtggtg caggacaccc tgatcaaagc ttttaccaag caagggcagt
     6721 tccaggccgc cgcccaatgg caaacctggg tgttcgccat tttgaaaaac accattctcg
     6781 acctgctgcg ccagcacaaa acccgcctgc aatggcaggt gagcagcgat gacgaagaat
     6841 ttatcgacgc cgtgcacgag cagctgttcg acgaaagcgg ccactggacg cccagtggca
     6901 gcccgcaggc ttgggcccag cccgaaagca gtctgcagca gcaagacttc atgcgcaccc
     6961 tgcaccactg cctgcaggac ctgcccgaaa acaccgcccg cgtgtttatg ctgcgcgaga
     7021 tcatgggttt ggacgtggcc gaaatctgcg aacaaaccgg catcagcgcc gacaactgtt
     7081 acactatcct gcatcgcgcc cgcaacggcc tgcgccgctg cctgcaaagc aactggttcg
     7141 acgaacaggc ctgatgcttt ttgatttgcc cgccgccttt cgcccataaa aaca
//
