LOCUS       NZ_CP050508.1          10624 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP050508.1 Raoultella terrigena strain JH01 chromosome, complete
            genome.
ACCESSION   NZ_CP050508
VERSION     NZ_CP050508.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:44:30
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5533579
            Orig. end    :: 5544203
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10624
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5538579:5539203](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5624)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10624
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10624
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(868..3654)
                     /locus_tag="ctg1_4988"
                     /transl_table=11
                     /translation="MVQIPENPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNM
                     LRSLILQYQPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHTMVKAMGL
                     PLMAVPGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPD
                     EVVTKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEAEKIA
                     GLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELDLSCEELLVLEPAADDLLTLFKK
                     YEFKRWITDVESGKWMQAKGSKPAAKPAQAAVAEEEVVEAAATLSAENYVTILDEETLT
                     AWIEKLKKAPLFSFDTETDSLDNISANMVGLSFAIEPGVAAYVPVAHDYLDAPDQIPRD
                     RVLELLKPLLEDNSLLKVGQNLKYDRGILANYGIELRGIAFDTMLESYILDSVAGRHDM
                     DSLSDRWLQHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPKLQ
                     QHEGPLHVFKNIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAKRLVELEQKAYEIAGE
                     EFNLSSPKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAK
                     LKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFI
                     APQDYLIVSADYSQIELRIMAHLSRDNGLLTAFAEGKDIHRATAAEVFSLPLESVSSEQ
                     RRSAKAINFGLIYGMSAFGLARQLNIPRREAQKYMDLYFERYPGVLDYMERTRAQAKEQ
                     GYVETLDGRRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDEWLLTEK
                     PRVRMIMQVHDELVFEVHKDDLESVAKKVHELMENSTTLAVPLLVEVGSGENWDQAH"
     aSDomain        complement(871..3630)
                     /aSDomain="TIGR00593"
                     /aSTool="tigrfam"
                     /description="pola: DNA polymerase I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4988_0037"
                     /evalue="9.70E-288"
                     /identifier="TIGR00593"
                     /label="ctg1_4988"
                     /locus_tag="ctg1_4988"
                     /protein_end="928"
                     /protein_start="8"
                     /score="955.2"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLILQY
                     QPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHTMVKAMGLPLMAVPGV
                     EADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYGV
                     PPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEAEKIAGLSFRGAK
                     TMAAKLEQNKEVAYLSYQLATIKTDVELDLSCEELLVLEPAADDLLTLFKKYEFKRWIT
                     DVESGKWMQAKGSKPAAKPAQAAVAEEEVVEAAATLSAENYVTILDEETLTAWIEKLKK
                     APLFSFDTETDSLDNISANMVGLSFAIEPGVAAYVPVAHDYLDAPDQIPRDRVLELLKP
                     LLEDNSLLKVGQNLKYDRGILANYGIELRGIAFDTMLESYILDSVAGRHDMDSLSDRWL
                     QHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPKLQQHEGPLHV
                     FKNIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAKRLVELEQKAYEIAGEEFNLSSPK
                     QLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDK
                     LPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPQDYLIV
                     SADYSQIELRIMAHLSRDNGLLTAFAEGKDIHRATAAEVFSLPLESVSSEQRRSAKAIN
                     FGLIYGMSAFGLARQLNIPRREAQKYMDLYFERYPGVLDYMERTRAQAKEQGYVETLDG
                     RRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDEWLLTEKPRVRMIMQ
                     VHDELVFEVHKDDLESVAKKVHELMENSTTLAVPLLVEVGSGENWDQAH"
     PFAM_domain     complement(880..2001)
                     /aSDomain="DNA_pol_A"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00476.22"
                     /description="DNA polymerase family A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4988_0140"
                     /evalue="8.80E-159"
                     /label="ctg1_4988"
                     /locus_tag="ctg1_4988"
                     /protein_end="925"
                     /protein_start="551"
                     /score="528.6"
                     /tool="antismash"
                     /translation="LHAHSQEIAKRLVELEQKAYEIAGEEFNLSSPKQLQTILFEKQGI
                     KPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRV
                     HTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPQDYLIVSADYSQIELRIM
                     AHLSRDNGLLTAFAEGKDIHRATAAEVFSLPLESVSSEQRRSAKAINFGLIYGMSAFGL
                     ARQLNIPRREAQKYMDLYFERYPGVLDYMERTRAQAKEQGYVETLDGRRLYLPDIKSSN
                     GARRAGAERAAINAPMQGTAADIIKRAMIAVDEWLLTEKPRVRMIMQVHDELVFEVHKD
                     DLESVAKKVHELMENSTTLAVPLLVEVGSGENWD"
     PFAM_domain     complement(2104..2667)
                     /aSDomain="DNA_pol_A_exo1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01612.22"
                     /description="3'-5' exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4988_0139"
                     /evalue="6.50E-44"
                     /label="ctg1_4988"
                     /locus_tag="ctg1_4988"
                     /protein_end="517"
                     /protein_start="329"
                     /score="149.9"
                     /tool="antismash"
                     /translation="YVTILDEETLTAWIEKLKKAPLFSFDTETDSLDNISANMVGLSFA
                     IEPGVAAYVPVAHDYLDAPDQIPRDRVLELLKPLLEDNSLLKVGQNLKYDRGILANYGI
                     ELRGIAFDTMLESYILDSVAGRHDMDSLSDRWLQHKTITFEEIAGKGKNQLTFNQIALE
                     EAGRYAAEDADVTLQLHLKMWPKLQ"
     PFAM_domain     complement(2848..3144)
                     /aSDomain="5_3_exonuc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01367.22"
                     /description="5'-3' exonuclease, C-terminal SAM fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4988_0138"
                     /evalue="3.70E-30"
                     /label="ctg1_4988"
                     /locus_tag="ctg1_4988"
                     /protein_end="269"
                     /protein_start="170"
                     /score="104.5"
                     /tool="antismash"
                     /translation="VPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLY
                     AEAEKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELDLSCEELLVLE"
     PFAM_domain     complement(3145..3630)
                     /aSDomain="5_3_exonuc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02739.18"
                     /description="5'-3' exonuclease, N-terminal resolvase-like
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4988_0137"
                     /evalue="1.50E-54"
                     /label="ctg1_4988"
                     /locus_tag="ctg1_4988"
                     /protein_end="170"
                     /protein_start="8"
                     /score="184.3"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLILQY
                     QPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHTMVKAMGLPLMAVPGV
                     EADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYG"
     CDS             4050..4949
                     /locus_tag="ctg1_4989"
                     /transl_table=11
                     /translation="MSRLLAAITLPLSIALTILVTIICSVPIIIAGVIKLLVPIPAVWR
                     AISHFCNFMMYCWCEGLALLLYLNPGLKWDVQGLEGLNKKNWYLLISNHHSWADIVVLC
                     VLFRKHIPMNKYFLKQQLAWVPFIGLACWALDMPFMRRYSRGYLIRHPERRGKDVATTR
                     RSCEKFRAYPTTIVNFVEGSRFTEEKQHQTRSPYSNLLPPKAAGVAMALNVLGSQFDKL
                     LDVTLCYPQNNRRPFYDMLSGRLTRIVVRVNLMPVAEELYGDYVNDKNFKRRFQRWLNE
                     LWQEKDARLTEMLQRQEK"
     PFAM_domain     4272..4736
                     /aSDomain="Acyltransferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01553.23"
                     /description="Acyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4989_0141"
                     /evalue="3.80E-13"
                     /label="ctg1_4989"
                     /locus_tag="ctg1_4989"
                     /protein_end="229"
                     /protein_start="74"
                     /score="49.3"
                     /tool="antismash"
                     /translation="DVQGLEGLNKKNWYLLISNHHSWADIVVLCVLFRKHIPMNKYFLK
                     QQLAWVPFIGLACWALDMPFMRRYSRGYLIRHPERRGKDVATTRRSCEKFRAYPTTIVN
                     FVEGSRFTEEKQHQTRSPYSNLLPPKAAGVAMALNVLGSQFDKLLDVTLCY"
     CDS             complement(5001..5624)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4990"
                     /sec_met_domain="TIGR03651 (E-value: 0.00036, bitscore:
                     19.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIWLALAGMILAFSASAAQITDGKQYITLEKPVAGEPQVLEFF
                     SFYCPHCYQFEEVLHVSDNVKKKLPEGVKMTKYHVEFLGPLGKDLTQAWAVAMALGVED
                     RITVPMFEAVQKTQTVQTVADIRKVFVDAGVKGEDYDAAWNSFVVKSLVAQQEKAAADL
                     QLQGVPAMYVNGKYQLNPQGMDTSNMDAFVAQYADTVKQLVEKK"
     PFAM_domain     complement(5037..5507)
                     /aSDomain="DSBA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01323.22"
                     /description="DSBA-like thioredoxin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4990_0142"
                     /evalue="1.10E-28"
                     /label="ctg1_4990"
                     /locus_tag="ctg1_4990"
                     /protein_end="196"
                     /protein_start="39"
                     /score="100.5"
                     /tool="antismash"
                     /translation="QVLEFFSFYCPHCYQFEEVLHVSDNVKKKLPEGVKMTKYHVEFLG
                     PLGKDLTQAWAVAMALGVEDRITVPMFEAVQKTQTVQTVADIRKVFVDAGVKGEDYDAA
                     WNSFVVKSLVAQQEKAAADLQLQGVPAMYVNGKYQLNPQGMDTSNMDAFVAQY"
     CDS             complement(5652..6638)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4991"
                     /sec_met_domain="APH (E-value: 5.7e-43, bitscore: 145.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDKAFNFQTLHPDTIIDGLFDLGMRVDSGLTPLNSYENRVYQFQ
                     DEDRRRYVVKFYRPERWSAEQILEEHQFTFQLEQDEVPVAAPLLFNDRSLHQHQGFFFA
                     VFPSLGGRQFEADNLDQMEWVGRFLGRLHQTGRKQLFVARPEIGIKEYLLEPRAVFEHS
                     TLIPAGLKKRFLAAADKLIEAVTAKWDGGAKILRLHGDCHAGNILWRDGPLFVDLDDAR
                     NGPAIQDLWMLLNGDKAEQRMQLETIVEAYEEFSPFNTDEIALIEPLRAMRLVYYLAWL
                     LRRWDDPAFPINFPWLTGEDYWRGQTKTFLEQVKVLQEPPLQLTPMY"
     PFAM_domain     complement(5874..6545)
                     /aSDomain="APH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01636.25"
                     /description="Phosphotransferase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4991_0143"
                     /evalue="1.10E-43"
                     /label="ctg1_4991"
                     /locus_tag="ctg1_4991"
                     /protein_end="255"
                     /protein_start="31"
                     /score="150.0"
                     /tool="antismash"
                     /translation="TPLNSYENRVYQFQDEDRRRYVVKFYRPERWSAEQILEEHQFTFQ
                     LEQDEVPVAAPLLFNDRSLHQHQGFFFAVFPSLGGRQFEADNLDQMEWVGRFLGRLHQT
                     GRKQLFVARPEIGIKEYLLEPRAVFEHSTLIPAGLKKRFLAAADKLIEAVTAKWDGGAK
                     ILRLHGDCHAGNILWRDGPLFVDLDDARNGPAIQDLWMLLNGDKAEQRMQLETIVEAYE
                     EF"
     CDS             complement(6714..6983)
                     /locus_tag="ctg1_4992"
                     /transl_table=11
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLIQFLQKLAKEAGYEGELADL
                     SDDILIYHLKMRDSTKEAVIPGIKKDYEEDFKTALLRARGVIKE"
     PFAM_domain     complement(6726..6983)
                     /aSDomain="DUF1040"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06288.15"
                     /description="Protein of unknown function (DUF1040)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4992_0144"
                     /evalue="6.90E-46"
                     /label="ctg1_4992"
                     /locus_tag="ctg1_4992"
                     /protein_end="86"
                     /protein_start="0"
                     /score="154.7"
                     /tool="antismash"
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLIQFLQKLAKEAGYEGELADL
                     SDDILIYHLKMRDSTKEAVIPGIKKDYEEDFKTALLRARGV"
     CDS             7055..7645
                     /locus_tag="ctg1_4993"
                     /transl_table=11
                     /translation="MQGEAITGVVLAGGKATRMGGVDKGLQRLNGQPLWRYVTDALQPQ
                     VTNLAISANRNLQSWQATGYPIYTDSLSDFPGPLAGMLSVMQQIECPWFVFCPCDTPFI
                     PPFLVARLMQQKQASPVVWAHDGERDHPAIALIHRRLIPQLEAYLAAGERRVMVFMRQA
                     GGHSVDFSDVKSAFINVNTLADLQHIHDMQEPL"
     aSDomain        7070..7615
                     /aSDomain="TIGR02665"
                     /aSTool="tigrfam"
                     /description="molyb_mobA: molybdenum cofactor
                     guanylyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4993_0038"
                     /evalue="2.90E-70"
                     /identifier="TIGR02665"
                     /label="ctg1_4993"
                     /locus_tag="ctg1_4993"
                     /protein_end="187"
                     /protein_start="5"
                     /score="234.1"
                     /tool="antismash"
                     /translation="ITGVVLAGGKATRMGGVDKGLQRLNGQPLWRYVTDALQPQVTNLA
                     ISANRNLQSWQATGYPIYTDSLSDFPGPLAGMLSVMQQIECPWFVFCPCDTPFIPPFLV
                     ARLMQQKQASPVVWAHDGERDHPAIALIHRRLIPQLEAYLAAGERRVMVFMRQAGGHSV
                     DFSDVKSAFINVNTLADLQ"
     PFAM_domain     7076..7528
                     /aSDomain="NTP_transf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12804.9"
                     /description="MobA-like NTP transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4993_0145"
                     /evalue="3.00E-32"
                     /label="ctg1_4993"
                     /locus_tag="ctg1_4993"
                     /protein_end="158"
                     /protein_start="7"
                     /score="112.3"
                     /tool="antismash"
                     /translation="GVVLAGGKATRMGGVDKGLQRLNGQPLWRYVTDALQPQVTNLAIS
                     ANRNLQSWQATGYPIYTDSLSDFPGPLAGMLSVMQQIECPWFVFCPCDTPFIPPFLVAR
                     LMQQKQASPVVWAHDGERDHPAIALIHRRLIPQLEAYLAAGERRVMV"
     CDS             7642..8154
                     /locus_tag="ctg1_4994"
                     /transl_table=11
                     /translation="MIPVLAISAWSGTGKTTLLKQLIPALCAEGLRPGLIKHTHHDMDV
                     DKPGKDSYELRKAGAAQTIVASTQRWALMTETPDQEEVDLPWLVSRMDASKLDVVLVEG
                     FKHESVPKIVLFRQNGGHRVEDLVLDKYVIAVASDAPVTTSLPQLDLNDIAQIAAFIVR
                     WLEEQRG"
     PFAM_domain     7651..8058
                     /aSDomain="MobB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03205.16"
                     /description="Molybdopterin guanine dinucleotide synthesis
                     protein B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4994_0146"
                     /evalue="3.00E-48"
                     /label="ctg1_4994"
                     /locus_tag="ctg1_4994"
                     /protein_end="139"
                     /protein_start="3"
                     /score="163.2"
                     /tool="antismash"
                     /translation="VLAISAWSGTGKTTLLKQLIPALCAEGLRPGLIKHTHHDMDVDKP
                     GKDSYELRKAGAAQTIVASTQRWALMTETPDQEEVDLPWLVSRMDASKLDVVLVEGFKH
                     ESVPKIVLFRQNGGHRVEDLVLDKYVIAVASD"
     aSDomain        7651..8133
                     /aSDomain="TIGR00176"
                     /aSTool="tigrfam"
                     /description="mobB: molybdopterin-guanine dinucleotide
                     biosynthesis protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4994_0039"
                     /evalue="6.50E-52"
                     /identifier="TIGR00176"
                     /label="ctg1_4994"
                     /locus_tag="ctg1_4994"
                     /protein_end="164"
                     /protein_start="3"
                     /score="173.6"
                     /tool="antismash"
                     /translation="VLAISAWSGTGKTTLLKQLIPALCAEGLRPGLIKHTHHDMDVDKP
                     GKDSYELRKAGAAQTIVASTQRWALMTETPDQEEVDLPWLVSRMDASKLDVVLVEGFKH
                     ESVPKIVLFRQNGGHRVEDLVLDKYVIAVASDAPVTTSLPQLDLNDIAQIAAFIVRW"
ORIGIN
        1 ctgaatacgc tgactaatca gaaaagcctg gcgcgtacct caaaaacgcc gggacgtacc
       61 cagctgatta acctgttcga agttgccgac ggtaaacgcc tggtcgattt accgggctac
      121 ggctacgctc aggtccccga ggagatgaag atcaaatggc agcgggcgct gggtgaatac
      181 ctcgaaaaac gcctgtgtct gaaagggctg gttattttga tggatattcg ccatccgctg
      241 aaagacctcg accagcagat gatcgaatgg gccgtagaaa gcgatatcca ggtgctggtg
      301 ctgctgacta agtccgataa gctggccagc ggagcccgta aagcgcagct caatatggtg
      361 cgtgaggcgg tactcgcctt taacggtgat gtgcaggttg aggcgttctc ttcgctgaag
      421 aaatcaggcg tcgataagct gcggcagaag ctcgatagct ggtttaacga aatccctcct
      481 caggaagaga tcgaagacgg ggagtaatct ccgccagact ccccggataa cggcgcgcag
      541 cgccttattc gggcgacaaa atcaggccag ctcccaccac tccggtcgct aaaaactttt
      601 ctttcgcgca ataaaaaacg ccccggtcat aaatgaccgg ggcggctaaa atattcagcc
      661 aaatccgatt acgtgaagta aaaggtctga aagatagaac atcttacctc tgtaccctac
      721 gtcattaact ctactcttct ttcagttagg gagaaagcac tttttgtagt tttttttcac
      781 tctttacata gcaaattcga atgatcgtca caaaactcta taagttatgt tgcttactta
      841 cagaaaaacg ctctctccac gaaatactta gtgcgcttga tcccagtttt ctccgctacc
      901 cacttccacc agcagcggaa ccgccagcgt ggtgctgttt tccattaatt catggacctt
      961 tttcgccacg ctctcgaggt catctttatg cacttcaaag accagttcat cgtgcacctg
     1021 catgatcatt cgcacccgcg gcttctcggt cagcagccac tcatcaacgg caatcattgc
     1081 ccgcttaatg atatccgccg ccgtcccctg cattggcgcg ttgattgccg ctcgctcagc
     1141 gcctgcacga cgtgcgccgt tgctggattt gatgtccggg agatagagcc gacgaccgtc
     1201 cagggtttca acatatccct gctctttcgc ctgcgcgcgg gtgcgctcca tataatccag
     1261 cacgcccgga tagcgctcga agtagagatc catatacttt tgcgcttctc tgcgcggaat
     1321 attgagctgg cgcgcgaggc cgaatgcgct catgccgtag atcaaaccaa agttgatcgc
     1381 tttagcgcta cgacgctgct cgctgctgac gctctccagc ggcaggctaa agacctcagc
     1441 cgccgtcgcc cggtggatat ctttcccttc agcaaaagcg gtcagcaggc cattatcacg
     1501 agataaatgg gccatgatgc gcagttcaat ctgcgagtag tcggcagaga cgatgagata
     1561 atcctgcggc gcgataaacg cctgacgaat gcgtcgccct tcctcgttac gcaccggtat
     1621 attttgcagg ttagggtccg ttgaagagag tcgcccggta gcggtaacgg cctgatggta
     1681 tgaggtatgg acccggccgg ttttggggtt aatcatcagc ggcagcttat cggtatacgt
     1741 cgacttcagc ttggctagcc cacggtactc aagaatcacc ttcggcagcg gatagtccag
     1801 cgccagctct tccagcacct cttccgaagt cgatggcgcg ccgcccgggg ttttcttcag
     1861 cggtttaatg ccctgctttt caaacaaaat cgtttgcagc tgcttcggtg aggagagatt
     1921 gaactcttct ccggcgatct cataggcctt ctgctccagc tcaaccaggc gcttagcgat
     1981 ctcctgagaa tgggcgtgca gcaccgccgg atcaatttta accccgttgc gctcaacgcg
     2041 ggatagcacc gggaccagcg gcatctcgat gtttttaaat acgtgcagcg gcccttcgtg
     2101 ctgctgcagc ttcggccaca tcttcaggtg cagctgcaga gtaacgtcgg catcttcagc
     2161 cgcatagcgg cccgcttctt ccaacgcaat ctggttaaac gtaagctgat tctttccttt
     2221 gccggcaatc tcttcaaagg tgatggtttt atgctgaagc cagcgatcgg agaggctgtc
     2281 catgtcatga cgccccgcca cgctatcaag gatgtaggac tccagcatcg tatcgaaggc
     2341 aatgccgcgg agctcaatgc catagttcgc caaaatcccg cggtcgtact tcaggttttg
     2401 cccaacttta aggaggctat tatcttccag cagcggcttg agcagctcaa gcacgcgatc
     2461 gcgcgggatc tgatccggcg catcgagata atcatgcgca accggcacat aggccgcaac
     2521 gccgggttcg atagcgaacg acaggccgac catgttggcc gagatgttat ccaggctgtc
     2581 cgtttccgta tcgaaagaaa acagcggcgc ttttttgagc ttctcaatcc acgccgttaa
     2641 cgtctcttca tcaagaatgg tgacgtagtt ttcggcagac agcgttgccg cagcttcaac
     2701 aacctcttct tcagccaccg ccgcttgcgc cggttttgcc gcaggcttgc tcccttttgc
     2761 ctgcatccat ttgccggact ccacgtcggt tatccagcgc ttgaattcat actttttgaa
     2821 cagcgtcagc agatcgtccg ccgccggttc cagaaccagc agctcttcgc agctcagatc
     2881 cagctccacg tctgttttaa tggtcgccag ctgataggag aggtaggcca cctctttatt
     2941 ctgctcgagc ttcgccgcca ttgttttggc gccacggaag ctcaggccag cgattttttc
     3001 cgcttcggca tacagcgtat caaggccacc caatccctgt agcagggcct gagcggtttt
     3061 ctctccgact cccggaacgc ccggaatgtt atccgaggag tcgcccatca gggcgaggaa
     3121 atcgatgatc agctctggcg gaacgccgta cttcgtcacc acttcatccg ggccgaggat
     3181 cgtattggtc atggtgttaa tcagagtgat acccggagtg accagctggg ccatgtcctt
     3241 atcgccggta ctgatcaata ccgggcgacc cgctttttcg gcctcacgcg ccagggtgcc
     3301 aatcacatcg tcagcctcca cgcccggtac cgccatcagc ggcaggccca tcgctttcac
     3361 catcgtgtgc agcggctcaa tctgcgcgcg cagatcgtcg ggcatcggcg ggcggtggga
     3421 tttgtagtgc tcaaacagtt cgtcacggaa agttttccct ttggcatcaa acaccaccac
     3481 ggcatgggtg ggctggtact gcaggatcag gcttcgcagc atattcagca cgccatacat
     3541 tgcgccagtc ggctcgccag cgctgttggt cagcggcggg aatgcgtgat acgcgcggta
     3601 aaggtaagag gagccgtcaa cgaggatgag agggttttca gggatctgaa ccataatttc
     3661 cgtgcctgtt tatcagatta tggataaagg atgccacaga caggcatgaa aacctgaatt
     3721 tttcccacat ttcgccgaaa agattcatcg atccggtcga tcctgcggca cagctatctg
     3781 tggataagtt tgtgcatagt tttaggccgg tagccatcgt gtatgaaaaa aagcgcgttt
     3841 cattataatt agtttttatt tatcatgtgg ttatatatag attattgatt taaagccgtc
     3901 acgatgactc aatgctccat gtggatataa gatccgcctg tttttctatt ctcgttagac
     3961 ccgtcatttg ctgcgttttc tgataaaatc aggctcttgc gctgtttaat cgcgctcttt
     4021 ctcagcctaa ctttctgaat aaaataacta tgtcgagatt actcgcagcg ataacgcttc
     4081 ctcttagtat cgctcttacc atcctggtca ccattatttg ttccgtaccg attattatcg
     4141 ccggagtgat taaactgctg gtgccgatcc ctgcggtatg gcgcgctatc tctcattttt
     4201 gtaatttcat gatgtactgc tggtgcgaag ggctggcgct gctgctgtac ctcaacccgg
     4261 ggctgaagtg ggacgtgcag ggtcttgaag ggctgaataa aaagaactgg tatctgctca
     4321 ttagcaatca tcacagctgg gcagatatcg tggtgctctg cgtgctgttc cgcaagcata
     4381 taccgatgaa caaatacttc ctcaagcagc agttagcctg ggtgcctttt atcggtcttg
     4441 cctgctgggc gctggatatg ccctttatgc gccgctactc gcgaggctat ctcattcgcc
     4501 atccggagcg ccgcggcaaa gatgtggcaa cgacccgtcg ttcctgcgag aaattccgcg
     4561 cttatccaac gaccatcgtt aactttgtag aagggtcacg tttcaccgag gagaaacagc
     4621 accagactcg ttcgccttat agcaacttat tgccaccaaa ggcggcaggc gttgcgatgg
     4681 ctctgaacgt actgggcagt cagttcgata agctgctgga cgtgacatta tgctatccgc
     4741 agaataaccg gcgccccttt tacgacatgc ttagcggccg cctcacgcga attgtggtcc
     4801 gcgttaatct gatgcccgtc gctgaagagc tgtacggtga ttacgtgaat gataagaact
     4861 ttaaacgtcg ctttcagcgc tggctgaacg agttatggca agaaaaagac gcccggctga
     4921 cggaaatgct acaacggcag gaaaagtaac tttattgagc ccgaaaacaa caacgccggt
     4981 cagtgaccgg cgttattttt ttatttcttc tcaaccagct gcttaacggt atcagcatac
     5041 tgggcgacaa atgcgtccat attgctggta tccatcccct gcgggttcag ctgatactta
     5101 ccattaacat acatcgccgg tacgccctgc agctgcaggt cagccgcggc tttttcctgc
     5161 tgggcaacca gagatttcac cacgaagctg ttccaggccg catcgtaatc ttcacccttc
     5221 acgccagcat caacgaagac tttacgaata tcggcaacgg tctgcacggt ttgtgttttc
     5281 tgcaccgcct caaacatcgg aacggtgatc cgatcttcaa cgcccagcgc catggccacc
     5341 gcccacgcct gagttaaatc tttgcccagc gggccaagga actcaacgtg gtacttcgtc
     5401 attttgacgc cttccggcag ctttttcttc acgttgtcag aaacgtgcag cacttcttca
     5461 aactgatagc agtgcgggca gtagaacgag aagaattcga gcacctgcgg ctcgccggca
     5521 accggcttct cgagggtaat gtactgcttg ccgtcggtta tctgggcagc ggatgcacta
     5581 aaagccagaa tcataccagc cagcgccagc caaatttttt tcatttttaa ctctctcctg
     5641 gaaatatcag attaatacat tggcgttaac tgaagagggg gttcctgtag aaccttcacc
     5701 tgctcaagaa aagttttggt ctgcccgcgc cagtagtctt ccccggtaag ccatgggaag
     5761 ttgataggga aggcaggatc gtcccagcgt cggagcaacc acgcaaggta gtagactaag
     5821 cgcatcgcgc gtaacggttc gatgagggca atttcgtcgg tgttaaacgg gctgaactct
     5881 tcataagctt caacgatcgt ctccagctgc atgcgctgtt cggctttatc accgttcagc
     5941 agcatccaga gatcctgaat agcggggccg ttgcgggcat catccagatc gacaaaaagc
     6001 gggccatcgc gccagaggat atttccggca tggcagtcac cgtgcaggcg caggatctta
     6061 gcgccgccgt cccacttcgc cgtgaccgcc tcgatcagct tatcagccgc agcgagaaaa
     6121 cgcttcttca ggccggccgg tatcagcgtt gagtgctcaa ataccgcgcg cggttcgagt
     6181 aaatattcct taatgccgat ctctggtcgg gcaacaaaga gctgcttgcg cccggtttga
     6241 tgcaggcggc caagaaaacg ccctacccat tccatctgat caaggttatc cgcttcaaac
     6301 tgacgcccgc ccaggcttgg gaaaacggca aagaagaagc cctggtgttg atgaagcgag
     6361 cgatcgttga agagcaacgg cgcggcgacg ggcacctcat cctgctctag ctggaaggta
     6421 aactggtgtt cttcgaggat ctgttcggca gaccaacgct caggacgata gaacttcacc
     6481 acatagcggc ggcgatcttc gtcctgaaac tggtaaacgc ggttttcata gctatttagc
     6541 ggggtgagac ctgagtctac ccgcatcccc agatcaaaca ggccatcgat gatggtatcc
     6601 gggtgaagcg tctgaaaatt gaaagcctta tcgtgcatcc tgacatccga taatcgtacg
     6661 aatagttcag gatatcatct cataactcat tctgtggtcg cacttacaac cttttactct
     6721 ttaatcacgc cgcgagcgcg cagcagcgcc gttttgaaat cttcttcgta gtctttctta
     6781 atccccggaa taacggcttc ttttgtcgag tcacgcatct tcagatggta aataagaata
     6841 tcgtcagaaa gatcggcgag ttccccctca taaccggcct ctttcgccag tttctgcaag
     6901 aattgaatca gattcagttc cggctctttt tgccaggctg gctggaggag ttcaataact
     6961 tcattcagac gtttacattt catgctcatg ctccttactc ttgataggga caagttaaca
     7021 gggtcaatcc cacaatgaaa gaggcgatat ttctatgcaa ggcgaggcaa taaccggcgt
     7081 cgtgctggcc ggcggaaaag ccacgcggat gggcggagtg gataaaggac tgcagcggct
     7141 aaacggacag ccgctatggc gctatgttac ggatgcgctg caaccgcagg tgaccaatct
     7201 ggcgatcagc gccaaccgta atctgcaaag ctggcaagcg acgggttacc caatctatac
     7261 cgatagcctt agcgattttc ccggaccgct ggccggtatg ctgtcggtga tgcagcagat
     7321 agagtgcccc tggtttgtat tttgcccctg tgacacgccg tttattccgc cgttcctggt
     7381 tgcgcgtttg atgcagcaga agcaggcctc accggtggtc tgggcgcacg atggggagcg
     7441 ggatcacccc gctatcgccc tgatacatcg tcggctaata ccacagctgg aggcctatct
     7501 ggcggccggc gaacggcggg tgatggtctt tatgcgccag gcaggcggac atagcgtcga
     7561 ttttagcgac gtaaagtctg cgtttattaa tgtgaatacg cttgctgact tacagcatat
     7621 tcacgatatg caggagccgt tatgatccct gttttagcaa tttctgcctg gagcggaacc
     7681 ggtaaaacaa cgttattaaa gcagctgatc cctgcattgt gcgccgaggg gttgcgcccg
     7741 ggtttgataa agcataccca tcacgatatg gatgtcgata agccagggaa agacagctat
     7801 gagctgcgca aagcaggcgc cgcgcagact attgtcgcca gtacgcagcg ctgggcgctg
     7861 atgactgaaa ctccggatca agaagaagta gacctgccgt ggctggttag ccggatggat
     7921 gcctcaaagc tggacgttgt gctggtagag ggttttaagc atgaatcagt gcctaagatc
     7981 gtgctttttc ggcaaaatgg cggccatcgc gttgaggatc ttgttcttga taagtacgtt
     8041 attgcggtgg ccagcgatgc gccggtgacg acttctttgc cccagctgga tttaaatgat
     8101 attgcgcaga tcgcggcatt tattgtccgc tggttagaag aacaacgcgg gtgatgagag
     8161 gcaagcttag cggctaaagg gtcagggatc gcggtacgcg gcccccgatc cgggcggcgt
     8221 caggtcactt ttcctgaacc gcagacaaca aaaaaacctc atgctttcgc atgaggtttc
     8281 tttgtttatt tgatgcctgg cagttcccta ctctcacatg gggagacccc acactaccat
     8341 cggcgctacg gcgtttcact tctgagttcg gcatggggtc aggtgggacc accgcgctat
     8401 tgccgccagg caaattctgt ttaccaacac gccatcaggc ctgtcagtta atctgtatca
     8461 gctgaaaatc tctcaaattc atcacaccaa acagctttgg cgttgtaagg ttaagcctca
     8521 cggttcatta gtatcggtta gctcaacgta tcgctacgct tacacacccg acctatcaac
     8581 gtcgtagtct tcaacgttcc ttcaggactc tcaaggagtc agggagaact catctcgggg
     8641 caagtttcgt gcttagatgc tttcagcact tatcttttcc gcatttagct accgggcaat
     8701 gccattggca tgacaacccg aacaccagtg atgcgtccac tccggtcctc tcgtactagg
     8761 agcagccccc ctcaattctc cagcgcccac ggcagatagg gaccgaactg tctcacgacg
     8821 ttctaaaccc agctcgcgta ccactttaaa cggcgaacag ccgtaccctt gggacctact
     8881 tcagccccag gatgtgatga gccgacatcg aggtgccaaa caccgccgtc gatatgaact
     8941 cttgggcggt atcagcctgt tatccccgga gtacctttta tccgttgagc gatggccctt
     9001 ccattcagaa ccaccggatc actatgacct gctttcgcac ctgctcgcgc cgtcacgctc
     9061 gcagtcaagc tagcttatgc cattgcacta acctcctgat gtccgaccag gattagctaa
     9121 ccttcgtgct cctccgttac tctttgggag gagaccgccc cagtcaaact acccaccaga
     9181 cactgtccgc aacccggatt acgggtctac gttagaacat caaacattaa agggtggtat
     9241 ttcaaggttg gctccacgca gactggcgtc cacgcttcaa agcctcccac ctatcctaca
     9301 catcaaggct caatgttcag tgtcaagcta tagtaaaggt tcacggggtc tttccgtctt
     9361 gccgcgggta cactgcatct tcacagcgag ttcaatttca ctgagtctcg ggtggagaca
     9421 gcctggccat cattacgcca ttcgtgcagg tcggaactta cccgacaagg aatttcgcta
     9481 ccttaggacc gttatagtta cggccgccgt ttaccggggc ttcgatcaag agcttctcct
     9541 tgcggataac cccatcaatt aaccttccgg caccgggcag gcgtcacacc gtatacgtcc
     9601 actttcgtgt ttgcacagtg ctgtgttttt aataaacagt tgcagccagc tggtatcttc
     9661 gactgatttc agctccgtga gcaagtcact tcacttacca tcagcgtgcc ttctcccgaa
     9721 gttacggcac cattttgcct agttccttca cccgagttct ctcaagcgcc ttggtattct
     9781 ctacctgacc acctgtgtcg gtttggggta cgatttgatg ttacctgatg cttagaggct
     9841 tttcctggaa gcagggcatt tgttacttca gcaccgtagt gcctcgtcat cacacctcag
     9901 cgttaataag agtccggatt tacctaaact ctccgcctac atgcttaaac cgggacaacc
     9961 gtcgcccggc taacatagcc ttctccgtcc ccccttcgca gtaacaccga gtacaggaat
    10021 attaacctgt ttcccatcga ctacgccttt cggcctcgcc ttaggggtcg actcaccctg
    10081 ccccgattaa cgttggacag gaacccttgg tcttccggcg agcgggcttt tcacccgctt
    10141 tatcgttact tatgtcagca ttcgcacttc tgatacctcc agcaaccctc acaggccacc
    10201 ttcaacggct tacagaacgc tcccctaccc aacaacgcct aagcgtcgct gccgcagctt
    10261 cggtgcatgg tttagccccg ttacatcttc cgcgcaggcc gactcgacca gtgagctatt
    10321 acgctttctt taaatgatgg ctgcttctaa gccaacatcc tggctgtctg tgccttccca
    10381 catcgtttcc cacttaacca tgactttggg accttagctg gcggtctggg ttgtttccct
    10441 cttcacgacg gacgttagca cccgccgtgt gtctcccgtg ataacattct tcggtattcg
    10501 tagtttgcat cgggttggta agtcgggatg accccctagc cgaaacagtg ctctaccccc
    10561 gaagatgagt tcacgaggcg ctacctaaat agctttcggg gagaaccagc tatctcccgg
    10621 tttg
//
