LOCUS       c00029_NZ_JAGZ..        8303 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAGZTV010000017.1 MAG: Klebsiella sp. isolate
            L2_037_016G1_dasL2_037_016G1_concoct_2 L2_037_016G1_scaffold_32,
            whole genome shotgun sequence.
ACCESSION   c00029_NZ_JAGZ..
VERSION     c00029_NZ_JAGZ..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:11:16
            Original ID  :: NZ_JAGZTV010000017.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8303
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8303
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2679:3303](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2680..3303
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..8303
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8303
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(153..671)
                     /locus_tag="ctg29_1"
                     /transl_table=11
                     /translation="MIPLLAIAAWSGTGKTTLLKSLIPALRAEGLRPGLIKHTHHDMDV
                     DKPGKDSYELRKAGAAQTIVASSQRWALMTETPEEPPLDLAWLVSRMDASTLDLVLVEG
                     FKHEAVPKILLFRQNSGHSIEELVYDDDVIAIASDTSVETSLPLLDLNDVPQITAFIMQ
                     WLKGFNEDR"
     aSDomain        complement(180..659)
                     /aSDomain="TIGR00176"
                     /aSTool="tigrfam"
                     /description="mobB: molybdopterin-guanine dinucleotide
                     biosynthesis protein B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg29_1_0001"
                     /evalue="1.60E-51"
                     /identifier="TIGR00176"
                     /label="ctg29_1"
                     /locus_tag="ctg29_1"
                     /protein_end="164"
                     /protein_start="4"
                     /score="172.4"
                     /tool="antismash"
                     /translation="LAIAAWSGTGKTTLLKSLIPALRAEGLRPGLIKHTHHDMDVDKPG
                     KDSYELRKAGAAQTIVASSQRWALMTETPEEPPLDLAWLVSRMDASTLDLVLVEGFKHE
                     AVPKILLFRQNSGHSIEELVYDDDVIAIASDTSVETSLPLLDLNDVPQITAFIMQW"
     PFAM_domain     complement(255..659)
                     /aSDomain="MobB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03205.16"
                     /description="Molybdopterin guanine dinucleotide synthesis
                     protein B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_1_0001"
                     /evalue="6.30E-48"
                     /label="ctg29_1"
                     /locus_tag="ctg29_1"
                     /protein_end="139"
                     /protein_start="4"
                     /score="162.1"
                     /tool="antismash"
                     /translation="LAIAAWSGTGKTTLLKSLIPALRAEGLRPGLIKHTHHDMDVDKPG
                     KDSYELRKAGAAQTIVASSQRWALMTETPEEPPLDLAWLVSRMDASTLDLVLVEGFKHE
                     AVPKILLFRQNSGHSIEELVYDDDVIAIASD"
     CDS             complement(668..1249)
                     /locus_tag="ctg29_2"
                     /transl_table=11
                     /translation="MQGKVITGVVLAGGRGSRMGGIDKGLQLLKGKALWRHVADALQPQ
                     VTKLVISANRNLDCWRSSGYPIITDSLNDFPGPLAGMLSVMHQVKGEWFLFCPCDTPFI
                     PSFLVMRLIQQRKSSPAVWVHDGERDHPAIALVHREAIGELETYLAAGERRVMVFLRKI
                     GGHSVDFSDVKSAFINVNTLDDLQRMQVPS"
     aSDomain        complement(689..1234)
                     /aSDomain="TIGR02665"
                     /aSTool="tigrfam"
                     /description="molyb_mobA: molybdenum cofactor
                     guanylyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg29_2_0002"
                     /evalue="2.30E-66"
                     /identifier="TIGR02665"
                     /label="ctg29_2"
                     /locus_tag="ctg29_2"
                     /protein_end="187"
                     /protein_start="5"
                     /score="221.3"
                     /tool="antismash"
                     /translation="ITGVVLAGGRGSRMGGIDKGLQLLKGKALWRHVADALQPQVTKLV
                     ISANRNLDCWRSSGYPIITDSLNDFPGPLAGMLSVMHQVKGEWFLFCPCDTPFIPSFLV
                     MRLIQQRKSSPAVWVHDGERDHPAIALVHREAIGELETYLAAGERRVMVFLRKIGGHSV
                     DFSDVKSAFINVNTLDDLQ"
     PFAM_domain     complement(776..1228)
                     /aSDomain="NTP_transf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12804.9"
                     /description="MobA-like NTP transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_2_0002"
                     /evalue="1.60E-31"
                     /label="ctg29_2"
                     /locus_tag="ctg29_2"
                     /protein_end="158"
                     /protein_start="7"
                     /score="109.9"
                     /tool="antismash"
                     /translation="GVVLAGGRGSRMGGIDKGLQLLKGKALWRHVADALQPQVTKLVIS
                     ANRNLDCWRSSGYPIITDSLNDFPGPLAGMLSVMHQVKGEWFLFCPCDTPFIPSFLVMR
                     LIQQRKSSPAVWVHDGERDHPAIALVHREAIGELETYLAAGERRVMV"
     PFAM_domain     1321..1578
                     /aSDomain="DUF1040"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06288.15"
                     /description="Protein of unknown function (DUF1040)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_3_0003"
                     /evalue="8.60E-46"
                     /label="ctg29_3"
                     /locus_tag="ctg29_3"
                     /protein_end="86"
                     /protein_start="0"
                     /score="154.3"
                     /tool="antismash"
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLMQFLQKLAKEAGYTGELNDL
                     SDDILIYHLKMRDSAKEAVIPGIQKDYEEDFKTALLRARGV"
     CDS             1321..1590
                     /locus_tag="ctg29_3"
                     /transl_table=11
                     /translation="MKCKRLNEVIELLQPAWQKEPELNLMQFLQKLAKEAGYTGELNDL
                     SDDILIYHLKMRDSAKEAVIPGIQKDYEEDFKTALLRARGVIKE"
     CDS             1666..2652
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_4"
                     /sec_met_domain="APH (E-value: 1e-43, bitscore: 142.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDKAFTFQTLHPDTIIDGLFDLGMRVDSGLTPLNSYENRVYQFQ
                     DEDRRRYVVKFYRPERWSAQQILEEHQFSLQLVQDEVPVAAPLSFNDSTLHQHQGFFFA
                     VFPSLGGRQFEADNLDQMEWVGRYLGRLHQTGRKQRFIARPEIGTNEYLLEPRQVFELS
                     PLIPAGLKEAFLSATDKLIDAVMAQWHGRANILRLHGDCHAGNILWRDGPLFVDLDDSR
                     NGPAIQDLWMLLNGDKAEQRMQLEMIIEAYEEFSAFNTDEIALIEPLRAMRLVYYLAWL
                     LRRWEDPAFPKNFPWLTGEDYWRGQTTTFLEQVKVLQEPPLQLTPMY"
     PFAM_domain     1759..2433
                     /aSDomain="APH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01636.25"
                     /description="Phosphotransferase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_4_0004"
                     /evalue="2.20E-42"
                     /label="ctg29_4"
                     /locus_tag="ctg29_4"
                     /protein_end="256"
                     /protein_start="31"
                     /score="145.7"
                     /tool="antismash"
                     /translation="TPLNSYENRVYQFQDEDRRRYVVKFYRPERWSAQQILEEHQFSLQ
                     LVQDEVPVAAPLSFNDSTLHQHQGFFFAVFPSLGGRQFEADNLDQMEWVGRYLGRLHQT
                     GRKQRFIARPEIGTNEYLLEPRQVFELSPLIPAGLKEAFLSATDKLIDAVMAQWHGRAN
                     ILRLHGDCHAGNILWRDGPLFVDLDDSRNGPAIQDLWMLLNGDKAEQRMQLEMIIEAYE
                     EFS"
     CDS             2680..3303
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03651"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_5"
                     /sec_met_domain="TIGR03651 (E-value: 8.8e-06, bitscore:
                     18.9, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIWLALAGMILAFSASAAQITDGKQYITLDKPVAGEPQVLEFF
                     SFYCPHCYQFEEVLHVSDNVKKKLPEGVKMTKYHVEFLGPLGKDLTQAWAVAMALGVED
                     KITVPMFEAVQKNQTVQTVADIRKVFVDAGVKGEDYDAAWNSFVVKSLVAQQEKAAADF
                     QLQGVPAMYVNGKYQLNPQGMDTSNMDAFVAQYADTVKQLVEKK"
     PFAM_domain     2797..3267
                     /aSDomain="DSBA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01323.22"
                     /description="DSBA-like thioredoxin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_5_0005"
                     /evalue="1.40E-28"
                     /label="ctg29_5"
                     /locus_tag="ctg29_5"
                     /protein_end="196"
                     /protein_start="39"
                     /score="100.1"
                     /tool="antismash"
                     /translation="QVLEFFSFYCPHCYQFEEVLHVSDNVKKKLPEGVKMTKYHVEFLG
                     PLGKDLTQAWAVAMALGVEDKITVPMFEAVQKNQTVQTVADIRKVFVDAGVKGEDYDAA
                     WNSFVVKSLVAQQEKAAADFQLQGVPAMYVNGKYQLNPQGMDTSNMDAFVAQY"
     CDS             complement(3353..4090)
                     /locus_tag="ctg29_6"
                     /transl_table=11
                     /translation="MYCWCEGLALLLRLNPWLKWDVQGLDSLNKKNWYLLISNHHSWAD
                     IVVLCVLFRKHIPMNKYFLKQQLAWVPFIGLACWALDMPFMRRYSRGYLLRHPERRGKD
                     VETTRRSCEKFRAHPTTIVNFVEGSRFTEEKQQQTRSPYQNLLAPKAAGIAMALNVLGS
                     QFDKLLNVTLCYPENNQKPFYDMLSGRLTRVVVRVSLETVTEELHGDYVNDKNFKRRFQ
                     RWLNRLWEEKDRQLTEIMQQAEK"
     PFAM_domain     complement(3641..4030)
                     /aSDomain="Acyltransferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01553.23"
                     /description="Acyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_6_0006"
                     /evalue="1.20E-12"
                     /label="ctg29_6"
                     /locus_tag="ctg29_6"
                     /protein_end="150"
                     /protein_start="20"
                     /score="47.7"
                     /tool="antismash"
                     /translation="DVQGLDSLNKKNWYLLISNHHSWADIVVLCVLFRKHIPMNKYFLK
                     QQLAWVPFIGLACWALDMPFMRRYSRGYLLRHPERRGKDVETTRRSCEKFRAHPTTIVN
                     FVEGSRFTEEKQQQTRSPYQNLLAPK"
     CDS             4092..4280
                     /locus_tag="ctg29_7"
                     /transl_table=11
                     /translation="MKLQKTDIERQTAGIGTRSLINPATMIGTEQIMVTMIVMAILSGS
                     VIAASNLDIVNLFRKLG"
     CDS             4649..7438
                     /locus_tag="ctg29_8"
                     /transl_table=11
                     /translation="MVQIPENPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNM
                     LRSLILQYQPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGL
                     PLMAVPGVEADDVIGTLAREAEKVGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPD
                     EVVTKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIA
                     GLAFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELGCEDLMVAQPIADELLTLFKK
                     YEFKRWITDVESGKWMQVKGVKPAAKAVVAVADVADAEEKTATALSSENYVTILDEETL
                     LTWVESLKKAPLFAFDTETDSLDNVSANMVGLSIAIEPGVAAYVPVAHDYLDAPDQIPR
                     DRVLELLKPLLEDDKVLKVGQNLKYDRGILANYGIELRGIAFDTMLESYILDSVAGRHD
                     MDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPEL
                     QQNEGPLNVFKNIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAKRLIELEKKAYDIAG
                     EEFNLSSPKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLA
                     KLKSTYTDKLPLMISPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAF
                     IAPEDYLIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLESVSSE
                     QRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLEYMERTRTQAKE
                     QGYVETLDGRRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDSWLLSE
                     KPRVRMIMQVHDELVFEVHKDDLEAVAKKIHELMESSTTLAVPLLVEVGSGENWDQAH"
     PFAM_domain     4673..5158
                     /aSDomain="5_3_exonuc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02739.18"
                     /description="5'-3' exonuclease, N-terminal resolvase-like
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_8_0007"
                     /evalue="2.40E-54"
                     /label="ctg29_8"
                     /locus_tag="ctg29_8"
                     /protein_end="170"
                     /protein_start="8"
                     /score="183.6"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLILQY
                     QPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLMAVPGV
                     EADDVIGTLAREAEKVGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYG"
     aSDomain        4673..7435
                     /aSDomain="TIGR00593"
                     /aSTool="tigrfam"
                     /description="pola: DNA polymerase I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg29_8_0003"
                     /evalue="6.60E-287"
                     /identifier="TIGR00593"
                     /label="ctg29_8"
                     /locus_tag="ctg29_8"
                     /protein_end="929"
                     /protein_start="8"
                     /score="952.5"
                     /tool="antismash"
                     /translation="LILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLILQY
                     QPTHAVVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLMAVPGV
                     EADDVIGTLAREAEKVGRPVLISTGDKDMAQLVTPGITLINTMTNTILGPDEVVTKYGV
                     PPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLAFRGAK
                     TMAAKLEQNKEVAYLSYQLATIKTDVELELGCEDLMVAQPIADELLTLFKKYEFKRWIT
                     DVESGKWMQVKGVKPAAKAVVAVADVADAEEKTATALSSENYVTILDEETLLTWVESLK
                     KAPLFAFDTETDSLDNVSANMVGLSIAIEPGVAAYVPVAHDYLDAPDQIPRDRVLELLK
                     PLLEDDKVLKVGQNLKYDRGILANYGIELRGIAFDTMLESYILDSVAGRHDMDSLSDRW
                     LKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPELQQNEGPLN
                     VFKNIEMPLVPVLSRVERNGVKIDPAVLHAHSQEIAKRLIELEKKAYDIAGEEFNLSSP
                     KQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTD
                     KLPLMISPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYLI
                     VSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLESVSSEQRRSAKAI
                     NFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLEYMERTRTQAKEQGYVETLD
                     GRRLYLPDIKSSNGARRAGAERAAINAPMQGTAADIIKRAMIAVDSWLLSEKPRVRMIM
                     QVHDELVFEVHKDDLEAVAKKIHELMESSTTLAVPLLVEVGSGENWDQAH"
     PFAM_domain     5159..5458
                     /aSDomain="5_3_exonuc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01367.22"
                     /description="5'-3' exonuclease, C-terminal SAM fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_8_0008"
                     /evalue="1.50E-29"
                     /label="ctg29_8"
                     /locus_tag="ctg29_8"
                     /protein_end="270"
                     /protein_start="170"
                     /score="102.5"
                     /tool="antismash"
                     /translation="VPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLY
                     AEPEKIAGLAFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELGCEDLMVAQP"
     PFAM_domain     5639..6202
                     /aSDomain="DNA_pol_A_exo1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01612.22"
                     /description="3'-5' exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_8_0009"
                     /evalue="1.90E-43"
                     /label="ctg29_8"
                     /locus_tag="ctg29_8"
                     /protein_end="518"
                     /protein_start="330"
                     /score="148.3"
                     /tool="antismash"
                     /translation="YVTILDEETLLTWVESLKKAPLFAFDTETDSLDNVSANMVGLSIA
                     IEPGVAAYVPVAHDYLDAPDQIPRDRVLELLKPLLEDDKVLKVGQNLKYDRGILANYGI
                     ELRGIAFDTMLESYILDSVAGRHDMDSLSDRWLKHKTITFEEIAGKGKNQLTFNQIALE
                     EAGRYAAEDADVTLQLHLKMWPELQ"
     PFAM_domain     6305..7426
                     /aSDomain="DNA_pol_A"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00476.22"
                     /description="DNA polymerase family A"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg29_8_0010"
                     /evalue="2.00E-158"
                     /label="ctg29_8"
                     /locus_tag="ctg29_8"
                     /protein_end="926"
                     /protein_start="552"
                     /score="527.5"
                     /tool="antismash"
                     /translation="LHAHSQEIAKRLIELEKKAYDIAGEEFNLSSPKQLQTILFEKQGI
                     KPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMISPKTGRV
                     HTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYLIVSADYSQIELRIM
                     AHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLESVSSEQRRSAKAINFGLIYGMSAFGL
                     ARQLNIPRKEAQKYMDLYFERYPGVLEYMERTRTQAKEQGYVETLDGRRLYLPDIKSSN
                     GARRAGAERAAINAPMQGTAADIIKRAMIAVDSWLLSEKPRVRMIMQVHDELVFEVHKD
                     DLEAVAKKIHELMESSTTLAVPLLVEVGSGENWD"
ORIGIN
        1 gtgtggggtc tccccatgtg agagtaggga actgccaggc atcaaacaag tgaagagccc
       61 atcctgacgg atgggctttt tgcgtttttg tcgcctgaaa atatcagcag atgccttcag
      121 aaggcgcgat catggctata tctctgctat aactatcggt cctcgttaaa cccctttaac
      181 cactgcataa taaaagcggt tatttgcggg acatcattta aatctaacaa tggaagagac
      241 gtctcgaccg acgtatcgct ggctatggca atcacgtcat cgtcataaac taattcttca
      301 atactatgtc cgctgttttg ccgaaaaagc aggattttag gcacagcttc atgcttaaaa
      361 ccctcaacaa ggactaaatc taatgttgat gcatccattc ggctaaccag ccatgccaga
      421 tccagcggag gctcttcggg ggtttccgtc attaatgccc aacgctggga gctggcgaca
      481 atcgtctgag ccgctccggc tttacgcagt tcatagctgt ctttaccggg cttatccacg
      541 tccatatcgt gatgagtatg tttaattagc cctggtcgta agccttccgc gcgcagtgcc
      601 ggaatcagcg acttcagtag ggtggtttta cctgtaccgc tccaggctgc gatggctaaa
      661 agcgggatca tgatggcacc tgcatacgtt gcaaatcgtc gagagtattg acgttaataa
      721 atgctgattt tacatcacta aaatcgacgc tatgaccgcc aattttgcgc agaaatacca
      781 ttacccgtct ttctcctgcg gccagatacg tttccagttc gccgatcgcc tcgcgatgca
      841 ccagagcaat ggccggatgg tcacgttcac catcgtgtac ccaaacggct ggagaagatt
      901 ttctctgctg tattaagcgc atcaccagaa atgatgggat aaatggcgta tcacagggac
      961 aaaacagaaa ccactccccc ttaacctgat gcattacgga aagcatgccg gccaacggcc
     1021 cgggaaagtc gttcagagag tcggtaataa tcgggtaacc gctgcttcgc cagcaatcaa
     1081 gattgcggtt agcgctaatc accagctttg taacctgcgg ctgcagcgca tcggcgacat
     1141 gacgccacag ggctttacct tttagcagct gtaatccttt atctattcct cccatgcgtg
     1201 agcctcttcc tcccgccagc acgacgccgg ttatgacctt gccctgcata ttaatatcgc
     1261 ctctttcatt gtgggattgt ccctgctaac gtattcctat caagagtaag gagcattgct
     1321 atgaaatgta aacgtctgaa tgaagtcatt gaactcctcc agccagcctg gcagaaagaa
     1381 cccgagctga atttaatgca atttttgcaa aaattggcga aagaggccgg atacaccggt
     1441 gagttgaacg atctctccga cgatattctg atttatcatc tgaagatgcg cgactcggca
     1501 aaagaagccg ttattcccgg gattcagaaa gattatgaag aagattttaa aaccgcgctg
     1561 ctacgcgctc gcggcgtgat taaagagtaa aaggttgtaa gcgctgccgc ggaatcgaca
     1621 atgagatgat atcctgtatc attcgtacga ttatcggatg tcaggatgca cgataaggct
     1681 ttcacttttc agacgcttca cccagatacc atcattgatg gcttatttga tctgggaatg
     1741 cgggtggact ccggtctcac tccgcttaat agctatgaga accgggttta ccagtttcag
     1801 gacgaagatc gtcgccgcta tgtggtgaag ttctatcgtc ctgagcgttg gtcagcccaa
     1861 cagatcctcg aagaacatca gttttccctc cagctcgtgc aggatgaagt ccctgtagcg
     1921 gcgccgttgt cgtttaacga cagtaccctt catcagcatc agggattctt tttcgccgta
     1981 ttcccaagcc tgggtggacg tcagtttgag gcggataacc tcgatcagat ggaatgggtt
     2041 ggacgctacc ttggccgtct gcatcaaact ggacgcaaac agcgttttat cgcacgtccg
     2101 gagataggga cgaatgagta tcttcttgag ccacgccagg tctttgagct ttccccgctg
     2161 ataccagcag gtctgaaaga ggcttttctc agcgctaccg ataagctgat tgatgcggta
     2221 atggcgcaat ggcacggacg cgccaatatt ttacggttac acggtgattg ccatgcggga
     2281 aacatcctct ggcgcgatgg gcccctgttt gttgatttag atgattcacg taatggacct
     2341 gctatccagg atctgtggat gttgttgaat ggcgataaag ccgagcaacg gatgcagctt
     2401 gagatgatca ttgaagcgta tgaagagttc agcgctttca ataccgatga aattgccctt
     2461 atcgaacctt tacgtgcaat gcggttagtt tattatctgg cgtggttatt aaggcgctgg
     2521 gaagatcccg cttttcctaa aaacttcccg tggttaaccg gggaagatta ctggcgcggg
     2581 cagacaacaa cttttcttga gcaggtaaag gttctgcagg aaccgcctct tcagttaacg
     2641 ccaatgtatt aatgtgatat atccaggaga gaattaatca tgaaaaaaat ttggctggcg
     2701 ctggctggta tgattctggc tttcagtgca tccgctgccc agatcaccga cggtaagcag
     2761 tatattaccc tcgataagcc cgttgccggt gagccgcagg tgctcgagtt tttctcgttc
     2821 tactgcccgc attgctatca gtttgaagaa gttcttcatg tgtcagataa cgtgaagaaa
     2881 aagctgcctg aaggcgtcaa aatgacgaaa taccacgttg agttcctggg accgttaggc
     2941 aaggatctga ctcaggcgtg ggccgttgcg atggcgctgg gcgtggaaga taaaatcacc
     3001 gtgccgatgt ttgaagcggt acagaaaaac cagaccgtcc agaccgtggc cgatattcgt
     3061 aaggtcttcg ttgacgccgg cgttaaaggt gaagattacg atgcagcctg gaacagcttt
     3121 gtggtgaaat ccctggtggc tcagcaagag aaagccgccg ctgatttcca gctgcagggc
     3181 gtgccggcta tgtacgttaa cggtaaatac cagcttaacc cgcagggtat ggataccagc
     3241 aacatggacg catttgttgc ccagtatgcc gataccgtta agcagctcgt tgagaagaaa
     3301 taaaaaataa acgccggtta ctgaccggcg tttttctttt ctgcatccac aattatttct
     3361 ccgcctgctg cattatttcc gttagctgcc gatctttctc ttcccaaagc ctgtttagcc
     3421 agcgctgaaa gcgtcgctta aagtttttgt catttacata atcgccgtgc agctcttccg
     3481 tcacagtctc aaggctgact cgcaccacaa cccgcgttaa tcggccgctc agcatgtcat
     3541 aaaacggctt ttggttgttt tccggatagc ataacgtgac gttcaaaagc ttatcaaact
     3601 gcgagccgag cacgtttaat gccatggcaa tacccgcagc ctttggcgct aacagattct
     3661 ggtatggtga acgggtctgc tgttgctttt cttccgtgaa acgagagcct tcgacaaagt
     3721 taacaatcgt tgttggatgc gcgcggaatt tctcgcagga gcggcgagtg gtttcaacat
     3781 ctttgccccg gcgctctgga tggcggagta aataacctcg ggaatagcgg cgcataaaag
     3841 gcatatccag cgcccagcag gccaacccaa taaacggcac ccaggcgagc tgttgcttga
     3901 ggaaatattt attcatcggg atatgtttgc gaaacagcac gcaaagcacc acgatatctg
     3961 cccagctatg gtggttgctg atgagcagat accagttttt cttattcagg ctatccaggc
     4021 cctgtacatc ccatttaagc cagggattaa gacgcagcag cagggccagc ccttcacacc
     4081 agcagtacat catgaaattg caaaaaacgg atatcgagcg ccagaccgca ggaataggca
     4141 caagaagttt aatcaacccg gcgacgatga ttggcaccga gcagattatg gtgactatga
     4201 tagtcatggc gatactcagc gggagcgtta tcgcggcgag taatctcgac atagttaatt
     4261 tattcagaaa gttaggctga aaaagaacgc ggttaaacgg cgcaagaggc tgattttacc
     4321 agaaaatagc gtaaataacg ggttttacca gaacagaaaa attttcggat cttatatcca
     4381 catggaacat tgagtcgcca tggtgttatt aaagcaaatt gtgaatgtat aacaaaatga
     4441 taaataagga ataatttgtt gatagatgat ttaattaacg attgtttggc tgtccttata
     4501 aaaatattca caaagttatc cacaggatgg cccataacgc gatcgaaagg atcgcagaat
     4561 cttttcgacg aaatgcggga aaaattcagg atttaatgcc cgtctgtggc atcctttacc
     4621 gataatctga taaacaggca cggaaattat ggttcagatc ccagaaaacc ctctcatcct
     4681 cgttgacggc tcctcttacc tttatcgggc atatcacgcg ttccccccgc tgacgaatag
     4741 cgctggtgaa ccgacaggcg caatgtatgg cgtgctgaat atgctgcgaa gcctgatcct
     4801 gcagtatcaa ccgacccatg ctgtcgtcgt gtttgatgcc aaggggaaga ctttccgtga
     4861 tgaactgttt gagcactata aatctcatcg cccgccgatg ccggacgatt tgcgtgcgca
     4921 gatcgagccg ctgcatgcca tggtaaaagc gatgggcctg ccgctaatgg ctgttcctgg
     4981 cgtagaagcc gatgatgtca tcggtaccct ggcgcgtgaa gctgaaaagg tcgggcgtcc
     5041 ggtactgatt agcaccggcg ataaagatat ggcccagctg gttacgccgg gtattacgct
     5101 gattaacacc atgaccaaca ctatccttgg ccctgatgaa gtggtgacga aatacggcgt
     5161 accaccggag ctgatcatcg attttctggc cctgatggga gattcatcgg acaatattcc
     5221 cggcgtacct ggcgtgggag aaaagacagc gcaggcgtta ctgcaggggc tggggggtct
     5281 tgatacgtta tacgctgagc ctgaaaaaat cgccgggctg gccttccgcg gcgcaaaaac
     5341 gatggccgca aagctggaac agaataaaga ggtggcttac ctctcctatc agctagcgac
     5401 gatcaaaacg gacgttgagc tggagctggg ctgtgaagat ttgatggttg cgcaacccat
     5461 cgctgatgaa ctgctcacgc tgtttaaaaa atatgaattc aaacgctgga tcaccgatgt
     5521 ggagtccggc aagtggatgc aggtaaaagg cgttaagcct gcggcgaagg cggttgtagc
     5581 ggtggctgac gtggctgatg cggaggagaa aaccgcgacg gcgctctctt ctgaaaatta
     5641 tgtcacgatc cttgatgaag aaaccttgtt aacctgggtt gagagcctga agaaagcgcc
     5701 gctttttgcc tttgataccg aaactgacag cctcgataac gtatccgcca atatggtcgg
     5761 tttatccatc gccattgagc ctggcgtagc ggcctatgta ccggttgccc atgattatct
     5821 ggatgcaccg gatcagatcc cgcgcgaccg tgtccttgaa ctgctgaaac cgctactgga
     5881 agatgacaag gttctgaagg ttggacaaaa cctcaaatat gaccgcggta tcctggctaa
     5941 ctacggcatt gaactgcgcg gtattgcctt tgataccatg ctggaatcct acattcttga
     6001 cagcgtggct ggccgccatg atatggatag cctctccgat cgctggctga agcacaaaac
     6061 cattaccttt gaagagattg cgggtaaagg taaaaaccag ctcaccttca atcagatcgc
     6121 gctggaagaa gcgggccgct acgcggcgga agatgccgat gtcacgctgc agctgcacct
     6181 caaaatgtgg cctgaacttc agcaaaatga aggcccgctg aacgtcttta aaaatattga
     6241 aatgccgctg gtgccggtgc tatcccgcgt ggagcgtaac ggggtgaaga ttgatccggc
     6301 cgtgctgcat gcgcattctc aggagatagc caaacgcctg attgaactgg agaagaaggc
     6361 gtatgatatc gcgggtgagg agtttaacct ctcttcgccg aagcagctgc aaaccatcct
     6421 gtttgaaaaa caaggtatta agccgctgaa gaaaaccccg ggcggcgcgc cgtctacctc
     6481 ggaagaggtg ctggaagagc tggcgctgga ctatccgctg ccgaaagtca tcctcgagta
     6541 tcgtggtctg gcaaaactca aatccaccta taccgataag ctgccgctga tgatcagccc
     6601 gaaaacgggc cgggttcaca cctcttatca ccaggcggtt acggcaacgg gacgtttgtc
     6661 gtctacagac ccgaacctgc agaacattcc ggtgcgcaac gaagaagggc ggcgtatccg
     6721 tcaggcgttt attgctccgg aagattatct cattgtctct gccgactact cgcaaattga
     6781 actgcgcatc atggcgcatc tttcccgtga taagggcctg ctgaccgcgt ttgcggaagg
     6841 gaaggatatc caccgcgcga cggcggcaga ggtctttggt ttgccgctgg agagcgtcag
     6901 cagcgaacag cgccgcagcg cgaaggcgat caacttcggc ctgatttacg gcatgagcgc
     6961 attcggcctt gcgcgtcagc tcaatattcc acgcaaagaa gcgcaaaagt atatggatct
     7021 ctactttgag cgctatccgg gcgtgctgga gtatatggag cgcacccgca cccaggccaa
     7081 agagcagggg tatgttgaaa cgcttgatgg ccgtcgtctc tacctgccgg acatcaaatc
     7141 cagcaacggc gcgcgccgcg ccggtgccga gcgtgcggcg attaatgcgc cgatgcaggg
     7201 aaccgctgcc gacattatta agcgcgcgat gatcgctgta gatagctggt tattaagcga
     7261 aaaaccgcgc gtgcggatga tcatgcaggt acacgatgaa ctggtctttg aagtgcataa
     7321 agacgacctt gaggcggttg cgaaaaagat ccacgaactg atggaaagca gcacgacgct
     7381 ggcggttccg ctgctggtgg aagtggggag tggagaaaac tgggatcaag cgcactaagt
     7441 attcggtaag gaaggtcatt tcttgtaagt gagtaacata acttatcgca ttttgtgatg
     7501 atcatttgaa tttgctatgt aaagagtgaa aaaaaactac aaaaaatgct ttatccgtaa
     7561 ccgaaagaag agtagagtta aagacgtagg gtacagaggt aagatgttct atctttcaga
     7621 ccttttactt cacgtaatcg gatttggctg aatattttag ccgcccatgc tgatgaggcg
     7681 ggctacccgg atagagcctc acgcgccgct atccggagaa gttagcgaga ttattcgccg
     7741 tcttcagagg cttcctgagg agggatatcg ttataccagc tatccagctt ctgccgtagt
     7801 ttatccacgc cctgcttctt cagggaagaa aacgcttcga cctgcacatc tccgttaaag
     7861 gcggtgaccg cttcacgaac catggcgatc tgcgcttttc gcgcgccgct ggccagttta
     7921 tcggctttag ttagcagtac cagtaccggg atatcgcttt ccaccgccca ttggatcatc
     7981 tgctgatcga gatctttaag cggatgacga atatccatca acacaaccag ccctttcaga
     8041 cagaggcgtt tctccagata ttcacccagc gcgcgctgcc acttgatttt catctcttcc
     8101 ggaacctggg catacccata gcccggcagg tcgaccaggc gcttaccttc agcgacttca
     8161 aacaggttaa taagctgcgt acggcctggc gtcttcgaag tacgcgcgag gcttttctgg
     8221 ttagtcagcg tgttcagcgc gctggatttc ccggcgttag agcggccagc aaaggccact
     8281 tcaataccgg tatcggcagg aag
//
